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Limb preservation

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https://www.readbyqxmd.com/read/27925241/vertebral-subluxation-repair-in-a-pet-goat
#1
Sara Nannarone, Enrico Bellezza, Yves P Moens, Paula Larenza Menzies
OBJECTIVES: To describe the perioperative management, including surgery, anesthesia, metabolic derangements, and physiotherapy, in a goat referred for paraparesis secondary to a road traffic accident. STUDY DESIGN: Case report. ANIMALS: 2-year-old mixed breed dwarf 44 kg female pet goat. METHODS: Clinical examination showed symptoms of early compensatory stages of shock, paraparesis with hyperextension of the thoracic limbs, pain on palpation of the thoracolumbar spine, increased patellar reflexes of both pelvic limbs without superficial sensitivity, but preserved deep pain sensation...
December 7, 2016: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/27919994/clinical-outcome-of-reconstruction-using-frozen-autograft-for-a-humeral-bone-tumor
#2
Hiroaki Kimura, Norio Yamamoto, Toshiharu Shirai, Hideji Nishida, Katsuhiro Hayashi, Yoshikazu Tanzawa, Akihiko Takeuchi, Shinji Miwa, Hiroyuki Tsuchiya
BACKGROUND: We developed a frozen autograft technique in which a tumor-bearing bone was treated with liquid nitrogen for reconstruction. The purpose of this study was to evaluate the functional outcomes of this technique after resection of humeral bone tumors. PATIENTS AND METHODS: Eight patients were included in the study. The freezing range was classified into 2 groups, depending on whether the joint surface of the humeral head was frozen. RESULTS: In the joint freezing group, the mean active shoulder abduction and flexion were 43...
December 2016: Anticancer Research
https://www.readbyqxmd.com/read/27909643/source-control-and-graft-preservation-using-negative-pressure-wound-therapy-with-antibiotic-instillation-a-case-report
#3
Victoria Gilbert, Timothy Kelly, Robert Grossi
Negative pressure wound therapy (NPWT) is widely used to treat many types of complex wounds, and the advent of the instillation and dwell time (NPWTi-d) technique has enhanced this system with the addition of automated treatment with topical solutions. In the field of vascular surgery, NPWT is utilized to help close wounds over underlying grafts; however keeping these wounds free of infection and avoiding large reoperation when infection occurs remains a challenge. In this case report we present a patient who required acute intervention for limb ischemia, with a large wound created in the groin for anastomosis of a prosthetic graft bypass...
October 31, 2016: Curēus
https://www.readbyqxmd.com/read/27870693/limb-salvage-with-intrepid-dynamic-exoskeletal-orthosis-versus-transtibial-amputation-a-comparison-of-functional-gait-outcomes
#4
Katharine I Mangan, Trevor D Kingsbury, Brittney N Mazzone, Marilynn P Wyatt, Kevin M Kuhn
OBJECTIVES: To determine if there is a difference in functional gait outcomes between patients with limb injuries treated with either transtibial amputation or limb preservation with the Intrepid Dynamic Exoskeletal Orthosis. DESIGN: Retrospective prognostic study. SETTING: Tertiary referral military hospital. PATIENTS: This study included 10 transtibial amputees and 10 limb preservation patients using the Intrepid Dynamic Exoskeletal Orthosis who were matched by body mass index after excluding for nontraumatic, proximal ipsilateral, contralateral, spine, or traumatic brain injuries...
December 2016: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/27870605/age-related-differences-in-locomotor-strategies-during-adaptive-walking
#5
Kristin A Lowry, Katherine Sebastian, Subashan Perera, Jessie Van Swearingen, Ann L Smiley-Oyen
Simultaneous control of lower limb stepping movements and trunk motion is important for skilled walking; adapting gait to environmental constraints requires frequent alternations in stepping and trunk motion. These alterations provide a window into the locomotor strategies adopted by the walker. The authors examined gait strategies in young and healthy older adults when manipulating step width. Anteroposterior (AP) and mediolateral (ML) smoothness (quantified by harmonic ratios) and stepping consistency (quantified by gait variability) were analyzed during narrow and wide walking while controlling cadence to preferred pace...
November 21, 2016: Journal of Motor Behavior
https://www.readbyqxmd.com/read/27863500/simultaneous-reconstruction-of-the-bone-and-vessels-for-complex-femoral-defect
#6
Shimpei Miyamoto, Masahide Fujiki, Nokitaka Setsu, Akira Kawai
BACKGROUND: Several methods have been reported for intercalary reconstruction of femoral defects. Of these, free vascularized fibula grafts (FVFG) are preferred because of their durability, bone-healing potential, and tolerance to infection. If the bone tumor invades the femoral vessels, simultaneous vascular reconstruction also becomes necessary and significant technical hurdles make limb salvage difficult. CASE PRESENTATION: We present a 10-year-old girl who underwent limb-sparing surgery for a distal femur osteosarcoma...
November 18, 2016: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27833453/benign-acute-childhood-myositis-complicating-influenza-b-infection-in-a-boy-with-idiopathic-nephrotic-syndrome
#7
Piotr Skrzypczyk, Joanna Przychodzień, Małgorzata Pańczyk-Tomaszewska
INTRODUCTION: Benign acute childhood myositis (BACM) is an acute complication of an infection characterized by calf pain, limitation of lower limb mobility, an increase in serum creatine kinase, and a self-limiting course. No reports of BACM in children with idiopathic nephrotic syndrome (INS) can be found in the literature. CASE REPORT: A 5-year-old boy with steroid-sensitive INS presented with fever, leg pain, and problems with walking. Physical examination showed pharyngeal erythema, preserved movements in all joints, and weakness of leg muscles...
2016: Central-European Journal of Immunology
https://www.readbyqxmd.com/read/27831542/a-late-cretaceous-diversification-of-asian-oviraptorid-dinosaurs-evidence-from-a-new-species-preserved-in-an-unusual-posture
#8
Junchang Lü, Rongjun Chen, Stephen L Brusatte, Yangxiao Zhu, Caizhi Shen
Oviraptorosaurs are a bizarre group of bird-like theropod dinosaurs, the derived forms of which have shortened, toothless skulls, and which diverged from close relatives by developing peculiar feeding adaptations. Although once among the most mysterious of dinosaurs, oviraptorosaurs are becoming better understood with the discovery of many new fossils in Asia and North America. The Ganzhou area of southern China is emerging as a hotspot of oviraptorosaur discoveries, as over the past half decade five new monotypic genera have been found in the latest Cretaceous (Maastrichtian) deposits of this region...
November 10, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27827819/prmt5-is-essential-for-the-maintenance-of-chondrogenic-progenitor-cells-in-the-limb-bud
#9
Jacqueline L Norrie, Qiang Li, Swanie Co, Bau-Lin Huang, Ding Ding, Jann C Uy, Zhicheng Ji, Susan Mackem, Mark T Bedford, Antonella Galli, Hongkai Ji, Steven A Vokes
During embryonic development, undifferentiated progenitor cells balance the generation of additional progenitor cells with differentiation. Within the developing limb, cartilage cells differentiate from mesodermal progenitors in an ordered process that results in the specification of the correct number of appropriately sized skeletal elements. The internal process by which these cells maintain an undifferentiated state while preserving their capacity to differentiate is unknown. Here, we report that the arginine methyltransferase PRMT5 has a critical role in maintaining progenitor cells...
November 8, 2016: Development
https://www.readbyqxmd.com/read/27821999/early-results-of-the-lps%C3%A2-limb-preservation-system-in-the-management-of-periprosthetic-femoral-fractures
#10
M Curtin, C Bryan, E Murphy, C G Murphy, W Curtin
INTRODUCTION: Achieving skeletal fixation in the presence of progressive bone loss is a surgical challenge, especially in cases of periprosthetic fracture (PPF). Unpredictable fracture patterns and preexisting bone loss frequently combine in this patient group. Megaprosthetic arthroplasty allows for immediate mobilisation and shorter periods of rehabilitation. We describe the clinical outcomes of a cohort of LPS™ megaprostheses performed for PPF by a single surgeon at our institution...
March 2017: Journal of Orthopaedics
https://www.readbyqxmd.com/read/27818979/functional-assessment-of-endoprosthesis-in-the-treatment-of-bone-tumors
#11
Denis Kiyoshi Fukumothi, Hiran Pupo, Luciano Augusto Reganin, Silvia Raquel Fricke Matte, Bruno Spagnuolo de Lima, Carlos Augusto de Mattos
OBJECTIVES: Evaluate the functional grade of these patients and to identify the types of complications found that influenced the average life span of endoprostheses the functions of the operated limb. METHODS: We analyzed 14 post-operative cases of endoprosthesis, patients with malignant bone tumors and aggressive benign bone tumors submitted to surgery between 2004 and 2014. The evaluation system used was proposed by Enneking, recommended by the Musculoskeletal Tumor Society (MSTS), in addition to the radiologic evaluation...
September 2016: Revista Brasileira de Ortopedia
https://www.readbyqxmd.com/read/27816483/sarcopenia-and-endothelial-function-in-patients-with-chronic-heart-failure-results-from-the-studies-investigating-comorbidities-aggravating-hf-sica-hf
#12
Marcelo R Dos Santos, Masakazu Saitoh, Nicole Ebner, Miroslava Valentova, Masaaki Konishi, Junichi Ishida, Amir Emami, Jochen Springer, Anja Sandek, Wolfram Doehner, Stefan D Anker, Stephan von Haehling
OBJECTIVES: Skeletal muscle wasting, also known as sarcopenia, has recently been identified as a serious comorbidity in patients with heart failure (HF). We aimed to assess the impact of sarcopenia on endothelial dysfunction in patients with HF with reduced ejection fraction (HFrEF) and with preserved ejection fraction (HFpEF). DESIGN: Cross-sectional study. SETTING: Ambulatory patients with HF were recruited at Charité Medical School, Campus Virchow-Klinikum, Berlin, Germany...
November 2, 2016: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/27808030/-a-free-musculocutaneous-flap-and-an-intramedullary-nail-made-the-use-of-a-prosthesis-possible-in-a-high-traumatic-femoral-amputation
#13
Jakob Felbo Paulsen, Finn Edgar Warburg, Knud Stenild Christensen, Rikke Holmgaard
The length of the stump and the quality of the soft tissue coverage are important for prosthesis fitting and mobility. In a high traumatic femoral amputation soft tissue reconstruction with a free musculocutaneous latissimus dorsi (LD) flap was performed to preserve bone length and provide proper tissue coverage. The extremely short stump was later on lengthened using a motorized intramedullary nail (Fitbone), and the achieved bone-lengthening was 14 cm. With the combined modalities of an LD-flap and Fitbone lengthening of the stump, the patient now has a useful limb function...
October 24, 2016: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/27795845/epigenetics-of-ancient-dna
#14
S V Zhenilo, A S Sokolov, E B Prokhortchouk
Initially, the study of DNA isolated from ancient specimens had been based on the analysis of the primary nucleotide sequence. This approach has allowed researchers to study the evolutionary changes that occur in different populations and determine the influence of the environment on genetic selection. However, the improvement of methodological approaches to genome-wide analysis has opened up new possibilities in the search for the epigenetic mechanisms involved in the regulation of gene expression. It was discovered recently that the methylation status of the regulatory elements of the HOXD cluster and MEIS1 gene changed during human evolution...
July 2016: Acta Naturae
https://www.readbyqxmd.com/read/27778451/management-of-extremely-hard-to-heal-extremity-wounds-with-severe-life-threatening-complications
#15
Aijia Cai, Anja M Boos, Andreas Arkudas, Raymund E Horch
The introduction of neoadjuvant radiotherapy has allowed limb-preserving surgical treatment in patients with extremity soft tissue sarcoma, and the overall prognosis of this approach is similar to that of limb amputation. The benefits of this treatment, however, are often accompanied with a higher risk of major complications and blood vessel damage because of radiation-induced inflammation and necrosis of the vessel wall. In particular, it is associated with the rupture of large vessels like the femoral artery and more severe complications of wounds located in the proximal lower extremity...
October 25, 2016: International Wound Journal
https://www.readbyqxmd.com/read/27765483/endovascular-treatment-of-transatlantic-inter-society-consensus-d-aortoiliac-occlusive-disease-using-unibody-bifurcated-endografts
#16
Robert M Van Haren, Lee J Goldstein, Omaida C Velazquez, Jagajan Karmacharya, Arash Bornak
OBJECTIVE: Aortobifemoral bypass has been the gold standard treatment for extensive aortoiliac occlusive disease. Endovascular therapy and stenting of aortic and iliac occlusive lesions has proven to be efficacious, especially when dealing with short segment lesions. Endovascular treatment of TransAtlantic Inter-Society Consensus II (TASC) D aortoiliac occlusive lesions remains a challenge, but a valuable treatment option in poor surgical candidates. We present our operative technique and midterm results in treating TASC D aortoiliac occlusive disease using unibody bifurcated endografts...
October 17, 2016: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/27763301/determinants-of-midterm-functional-outcomes-and-wound-healing-in-a-hospital-based-limb-preservation-program
#17
Bala Ramanan, Ayman Ahmed, Bian Wu, Marlin W Causey, Warren J Gasper, Shant M Vartanian, Jade S Hiramoto, Michael S Conte
No abstract text is available yet for this article.
August 2016: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/27760806/short-term-results-of-isolated-phlebectomy-with-preservation-of-incompetent-great-saphenous-vein-asval-procedure-in-primary-varicose-veins-disease
#18
Igor A Zolotukhin, Evgeny I Seliverstov, Elena A Zakharova, Alexander I Kirienko
OBJECTIVE: To establish an effect of isolated phlebectomy in patients with incompetent great saphenous vein (Ambulatory Selective Varices Ablation under Local anesthesia (ASVAL) procedure) on the reflux and diameter of the trunk and to assess recurrence rate of varicose veins at one year. MATERIAL AND METHODS: We conducted a prospective study on patients with primary varicose veins and with C2 or C2,3 or C2,3,4 or C2,4 classes of chronic venous disease and great saphenous vein incompetence...
October 19, 2016: Phlebology
https://www.readbyqxmd.com/read/27751708/effect-of-limb-preservation-status-and-body-mass-index-on-the-survival-of-patients-with-limb-threatening-diabetic-foot-ulcers
#19
Cheng-Wei Lin, Brend Ray-Sea Hsu, Jir-Shiong Tsai, Hui-Mei Yang, Jr-Rung Lin, Chia-Hung Lin, Chung-Huei Huang, Shih-Yuan Hung, Yu-Yao Huang
AIMS: To evaluate the effect of limb preservation status and body mass index (BMI) on the survival of patients with diabetic foot ulcers (DFUs). METHODS: A total of 1346 patients treated for limb-threatening DFUs at a major diabetic foot center in Taiwan from 2002 to 2009 were tracked until December 2012. The patients were classified into three groups: limb-preserved (n=858), minor lower-extremity amputation (LEA) (n=249), and major LEA (n=239). Clinical data during treatment were used for survival analysis...
September 30, 2016: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/27748302/the-making-of-indigenous-vascular-prosthesis
#20
Madathipat Unnikrishnan, Sidharth Viswanathan, K Balasubramaniam, C V Muraleedharan, Arthur Vijayan Lal, P V Mohanan, Meera Mohanty, Tirur Raman Kapilamoorthy
BACKGROUND & OBJECTIVES: Vascular illnesses are on the rise in India, due to increase in lifestyle diseases and demographic transition, requiring intervention to save life, organ or limbs using vascular prosthesis. The aim of this study was to develop indigenous large diameter vascular graft for treatment of patients with vascular pathologies. METHODS: The South India Textile Research Association, at Coimbatore, Tamil Nadu, India, developed seamless woven polyester (Polyethylene terephthalate) graft at its research wing...
June 2016: Indian Journal of Medical Research
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