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Limb preservation

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https://www.readbyqxmd.com/read/28549441/dynamic-arm-study-quantitative-description-of-upper-extremity-function-and-activity-of-boys-and-men-with-duchenne-muscular-dystrophy
#1
Mariska M H P Janssen, Jaap Harlaar, Bart Koopman, Imelda J M de Groot
BACKGROUND: Therapeutic management of upper extremity (UE) function of boys and men with Duchenne Muscular Dystrophy (DMD) requires sensitive and objective assessment. Therefore, we aimed to measure physiologic UE function of healthy subjects and DMD patients in different disease stages, and to evaluate the relation between these physiologic measures and functional UE scales. METHODS: Twenty-three DMD patients and twenty healthy controls (7-23 years) participated in this explorative case-control study...
May 26, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/28540806/laparoscopic-hyperthermic-isolated-limb-perfusion-a-new-minimally-invasive-approach-for-hilp
#2
N Solari, F Sucameli, M Gipponi, F De Cian, F Cafiero
BACKGROUND: Hyperthermic isolated limb perfusion (HILP) represents a limb-sparing treatment for unresectable soft tissue sarcoma (STS) of the extremities with substantial complete response rates. HILP often provides good functional limb preservation, hence a significant improvement also in terms of quality of life of the patient. Notwithstanding these clear advantages, the traditional technique is still hindered by relatively high post-operative morbidity. METHOD: We treated a 78-year-old female with unresectable angiosarcoma of the left leg using a new surgical approach: an entirely laparoscopic HILP...
April 24, 2017: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/28539669/sensorimotor-adaptation-as-a-behavioural-biomarker-of-early-spinocerebellar-ataxia-type-6
#3
Muriel T N Panouillères, Raed A Joundi, Sonia Benitez-Riveiro, Binith Cheeran, Christopher R Butler, Andrea H Németh, R Chris Miall, Ned Jenkinson
Early detection of the behavioural deficits of neurodegenerative diseases may help to describe the pathogenesis of such diseases and establish important biomarkers of disease progression. The aim of this study was to identify how sensorimotor adaptation of the upper limb, a cerebellar-dependent process restoring movement accuracy after introduction of a perturbation, is affected at the pre-clinical and clinical stages of spinocerebellar ataxia type 6 (SCA6), an inherited neurodegenerative disease. We demonstrate that initial adaptation to the perturbation was significantly impaired in the eighteen individuals with clinical motor symptoms but mostly preserved in the five pre-clinical individuals...
May 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28527156/the-effect-of-aerobic-or-aerobic-strength-exercise-on-body-composition-and-functional-capacity-in-patients-with-bmi-%C3%A2-35-after-bariatric-surgery-a-randomized-control-trial
#4
Alireza Hassannejad, Alireza Khalaj, Mohammad Ali Mansournia, Mastaneh Rajabian Tabesh, Zahra Alizadeh
BACKGROUND: Although previous studies suggested that bariatric surgery is the most effective and sustainable treatment method for morbid obesity in long term, but without changing in lifestyle, maintaining optimal weight loss is almost impossible. METHODS: Sixty morbid obese patients (BMI ≥ 35) were evaluated before and after 12 weeks of bariatric surgery in order to compare the impact of two different exercise programs on body composition and functional capacity outcomes...
May 19, 2017: Obesity Surgery
https://www.readbyqxmd.com/read/28508770/romuald-w%C3%A4-g%C3%A5-owski-1876-1935-orthopaedic-surgeon-forgotten-pioneer-of-limb-saving-tumour-surgery
#5
Marek Durakiewicz, Mirosław Jabłoński, Aneta Zarębska
On May 16, 1914, The Lancet Journal published a paper by Romuald Węgłowski, a Polish-born professor of Moscow University, entitled "Malignant tumours of bones: a new method in conservative operative treatment." The idea of biological resection presented in the paper consisted in thermocoagulation of the apparently cancerous part of a bone with a jet of steam. According to the author, dead bone rid of live malignant cells reconstructed itself quickly, which helped to preserve the functionality of the organ without considerable limitations...
April 12, 2017: Ortopedia, Traumatologia, Rehabilitacja
https://www.readbyqxmd.com/read/28503351/subtrochanteric-and-distal-femur-fractures-in-a-patient-with-femoral-shaft-fracture-malunion-and-knee-disarticulation-a-rare-and-challenging-case-report
#6
R E Pires, E O Santana, P J Labronici, I A Almeida Filho
This study aims to describe a rare and challenging case of a patient who presented ipsilateral subtrochanteric and distal femur fractures due to low-energy trauma. The peculiarity of this case is the presence of femoral shaft fracture malunion and knee disarticulation in the same limb resulting from an accident suffered 30 years ago. The patient underwent femoral diaphyseal osteotomy and fixation of the subtrochanteric and distal femur fractures with a long cephalomedullary nail and distal femur locking plate, respectively...
September 2016: Annals of Medical and Health Sciences Research
https://www.readbyqxmd.com/read/28502552/bifurcated-bifurcated-aneurysm-repair-is-a-novel-technique-to-repair-infrarenal-aortic-aneurysms-in-the-setting-of-iliac-aneurysms
#7
Susanna Hewon Shin, Benjamin Ware Starnes
BACKGROUND: Up to 40% of abdominal aortic aneurysms (AAAs) have coexistent iliac artery aneurysms (IAAs). In the past, successful endovascular repair required internal iliac artery (IIA) embolization, which can lead to pelvic or buttock ischemia. This study describes a technique that uses a readily available solution with a minimally altered off-the-shelf bifurcated graft in the IAA to maintain IIA perfusion. METHODS: From August 2009 to May 2015, 14 patients with AAAs and coexisting IAAs underwent repair with a bifurcated-bifurcated approach...
May 11, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28502548/lifelong-limb-preservation-a-patient-centered-description-of-lower-extremity-arterial-reconstruction-outcomes
#8
Katie E Shean, Peter A Soden, Marc L Schermerhorn, Sara L Zettervall, Sarah E Deery, Jeremy D Darling, Allen Hamdan, Frank W LoGerfo
BACKGROUND: Life expectancy is short for patients with critical limb ischemia (CLI), many of whom may fear amputation more than death. In light of the reduced life expectancy of these patients, the traditional 5-year freedom from amputation (FFA) statistic may not accurately address their concern. We developed a more relevant patient-centered calculation of major amputation risk during a patient's remaining lifetime to better answer the question, Will I ever lose my leg? METHODS: We identified all limbs undergoing first-time intervention for CLI in a large institutional database from 2005 to 2013...
May 11, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28502545/durability-of-iliac-artery-preservation-associated-with-endovascular-repair-of-infrarenal-aortoiliac-aneurysms
#9
Behzad S Farivar, Mohammad N Abbasi, Agenor P Dias, Yuki Kuramochi, Corey S Brier, F Ezequiel Parodi, Matthew J Eagleton
OBJECTIVE: This study evaluated and compared the long-term clinical outcomes of endovascular repair of infrarenal aortoiliac aneurysms (EVAR) vs EVAR with preservation of antegrade internal iliac artery (IIA) perfusion using iliac branched devices (EVAR-IBDs). METHODS: From October 1998 to August 2015, patients with infrarenal aortoiliac aneurysmal (AIA) disease at high risk for conventional open surgery were enrolled in a prospective physician-sponsored investigational device exemption trial...
May 11, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28495506/use-of-bipedicled-dorsal-penile-flap-with-z-release-incision-a-new-option-in-redo-hypospadias-surgery
#10
Hazem Elmoghazy
OBJECTIVES: To solve the challenge in redo hypospadias surgery; we tried the use of bipedicled dorsal penile flap with Z release incision in failed hypospadias cases and reported the outcome. MATERIAL AND METHODS: Thirty male children with 3 or 4 previous unsuccessful hypospadias surgeries were included in our study. Our technique was done after at least 6 month from the last surgery. A flap of the dorsal penile skin is preserved and the skin lateral is dissected on each side...
May 8, 2017: Urology
https://www.readbyqxmd.com/read/28493074/corrective-osteotomies-of-the-lower-limb-show-a-low-intra-and-perioperative-complication-rate-an-analysis-of-1003-patients
#11
Maximilian Schenke, Jörg Dickschas, Michael Simon, Wolf Strecker
PURPOSE: The purpose of corrective osteotomies in posttraumatic and congenital deformities is anatomic limb reconstruction and joint preservation. The aim of the present study was to analyse intra- and perioperative complications of osteotomies in the lower limb. METHODS: One thousand and three unselected and prospectively registered osteotomies of the long bones of the lower limb, performed between 1995 and 2013, were analysed. In 435 women and 568 men (mean age 39...
May 10, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28489541/the-effect-of-prosthesis-use-on-hand-mental-rotation-after-unilateral-upper-limb-amputation
#12
Xiaoli Guo, Zixuan Lin, Yuanyuan Lyu, Robin Bekrater-Bodmann, Herta Flor, Shanbao Tong
Amputation of a limb induces changes in the so-called body schema, which might be influenced by the use of prosthetic devices. Changes in the body representation associated with prosthesis use could be investigated using a hand mental rotation task. However, direct neurophysiologic evidence for the effect of prosthesis use on hand mental rotation is still lacking. In this study, we recruited two groups of unilateral upper-limb amputees, i.e., amputees using a prosthesis or with a history of prosthesis use (Pro group) and amputees without a prosthesis (non-Pro group), as well as a sample of matched healthy controls...
May 8, 2017: IEEE Transactions on Neural Systems and Rehabilitation Engineering
https://www.readbyqxmd.com/read/28483625/parallel-stenting-technique-in-a-sandwich-configuration-for-hypogastric-preservation-during-evar-an-in-vitro-study
#13
Xavier Yugueros, Gaspar Mestres, Savino Pasquadibisceglie, Xavier Alomar, Ana Apodaka, Vincent Riambau
PURPOSE: to identify the best conditions in iliac sandwich procedure for hypogastric preservation during EVAR; testing different devices, different oversizing degrees as well as different methods of measure it. METHODS: Four external iliac devices (16mm Endurant and 12mm Aorfix limb extensions; 11 and 13mm Viabahn endografts) were tested with two distinct internal iliac stentgrafts (8mm Advanta/V12 and 8mm Viabahn) inside different proximal silicon iliac limbs models (10, 12, 14, 16 and 18mm), simulating an iliac sandwich procedure for hypogastric preservation...
May 5, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28480286/the-association-between-geographic-density-of-infectious-disease-physicians-and-limb-preservation-in-patients-with-diabetic-foot-ulcers
#14
Meghan B Brennan, Glenn O Allen, Patrick D Ferguson, Joseph A McBride, Christopher J Crnich, Maureen A Smith
BACKGROUND: Avoiding major (above-ankle) amputation in patients with diabetic foot ulcers is best accomplished by multidisciplinary care teams with access to infectious disease specialists. However, access to infectious disease physicians is partially influenced by geography. We assessed the effect of living in a hospital referral region with a high geographic density of infectious disease physicians on major amputation for patients with diabetic foot ulcers. We studied geographic density, rather than infectious disease consultation, to capture both the direct and indirect (eg, informal consultation) effects of access to these providers on major amputation...
2017: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/28479466/perioperative-and-late-outcomes-after-endovascular-treatment-for-isolated-iliac-artery-aneurysms
#15
Claudio Bianchini Massoni, Antonio Freyrie, Mauro Gargiulo, Tiziano Tecchio, Chiara Mascoli, Enrico Gallitto, Gianluca Faggioli, Rodolfo Pini, Matteo Azzarone, Paolo Perini, Andrea Stella
AIM: The aim of the study was to report early and follow-up outcomes of the endovascular treatment with iliac endografts for isolated iliac artery aneurysms (IIAA). METHODS: Records of patients who underwent elective endovascular repair for isolated iliac artery aneurysms (both primary and para-anastomotic) from 2005 to 2015 in two Italian centres were retrospectively examined. Demographics data, preoperative patient comorbidities, iliac aneurysm characteristics, contralateral iliac axis involvement, patency of hypogastric arteries and inferior mesenteric artery (IMA) and data of endovascular treatment were obtained for analysis...
May 4, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28479423/treating-peripheral-artery-disease-in-the-wake-of-rising-costs-and-protracted-length-of-stay
#16
Grace J Wang, Benjamin M Jackson, Paul J Foley, Scott M Damrauer, Venkat Kalapatapu, Michael A Golden, Ronald M Fairman
OBJECTIVE: There has been growing scrutiny in the treatment of patients with peripheral artery disease (PAD) due to the utilization of resources to manage this complex patient population. The purpose of this study was to determine the factors associated with prolonged length of stay (LOS>7 days) following lower extremity bypass using data from the Vascular Quality Initiative (VQI) as well as to define the additional costs incurred due to prolonged LOS in our health system. METHODS: Summary statistics were performed of patients undergoing lower extremity bypass from 2010-2015...
May 4, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28470333/extracorporeal-perfusion-of-isolated-organs-of-large-animals-bridging-the-gap-between-in-vitro-and-in-vivo-studies
#17
Carola R Daniel, Raphael Labens, David Argyle, Theresia F Licka
Since the early 20th century extracorporeal perfusion of large animal organs has been used to investigate a broad variety of research questions, thereby overcoming common draw backs of in vitro studies without suffering from ethical concerns associated with live animal research. The technique is in accordance with the 3R principles and represents an excellent opportunity to investigate in detail the physiology of organs under standardised conditions. It is also suitable for the translation of basic pre-clinical research into a more relevant arena prior to or avoiding altogether live animal research...
May 3, 2017: ALTEX
https://www.readbyqxmd.com/read/28463613/against-the-odds-what-to-expect-in-rehabilitation-of-chronic-spinal-cord-injury-with-a-neurologically-controlled-hybrid-assistive-limb-exoskeleton-a-subgroup-analysis-of-55-patients-according-to-age-and-lesion-level
#18
Dennis Grasmücke, Amrei Zieriacks, Oliver Jansen, Christian Fisahn, Matthias Sczesny-Kaiser, Martin Wessling, Renate C Meindl, Thomas A Schildhauer, Mirko Aach
Objective Age and lesion level are believed to represent outcome predictors in rehabilitation of patients with chronic spinal cord injury (SCI). The Hybrid Assistive Limb (HAL) exoskeleton enables patients to perform a voluntary controlled gait pattern via an electromyography-triggered neuromuscular feedback system, and has been introduced as a temporary gait training tool in patients with SCI. The aim of this prospective pre- and postintervention study was to examine functional outcomes as a function of age and lesion level in patients with chronic incomplete SCI (iSCI) or chronic complete SCI (cSCI) with zones of partial preservation (ZPP) by using the HAL as a temporary training tool...
May 2017: Neurosurgical Focus
https://www.readbyqxmd.com/read/28458962/team-approach-helps-patient-survive-high-voltage-electric-burn
#19
Noha Saied, Ahmed Harfoush, Tamer Ayed, Alaa Moustafa, Rania Hassan, Ezz Eldolify, Hany Abdelaziz
A 20-year-old man was subjected to high-voltage electric burn, which was occupational. The patient was admitted to AlGalaa Military Medical Complex almost 2 weeks after the accident had happened. According to Lund and Browder's chart, the patient had a 40% total body surface area burn involving the upper limbs, anterior and posterior trunks, and the left thigh (third- and fourth-degree burns). The aim of this study was to stabilize the patient by conducting lifesaving operations in multiple scheduled sessions, bilateral below-elbow amputations, escharotomies, and excision of affected ribs and cartilages...
March 2017: Plastic and Reconstructive Surgery. Global Open
https://www.readbyqxmd.com/read/28458768/early-diagnosis-in-familial-glucocorticoid-deficiency
#20
Fatima Al Jneibi, Tawfiq Hen, Jaishen Rajah, Rajendran Nair
Familial glucocorticoid deficiency (FGD) is a rare autosomal recessive condition, characterized by marked atrophy of zona fasiculata and reticalaris with preservation of zona glomerulosa. Out of more than 50 published cases, 18 patients died as a result of glucocorticoid insufficiency. The main objective of this report is to emphasize the early diagnosis and treatment in our 17 month-old patient. Her presenting features following an upper respiratory tract infection were hypoglycemia, seizures as well as deep hyperpigmentation of the limbs and lips...
2017: Dermato-endocrinology
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