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"Cluster headache"

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https://www.readbyqxmd.com/read/28906127/cluster-headache-clinical-pattern-and-a-new-severity-scale-in-a-swedish-cohort
#1
Anna Steinberg, Carmen Fourier, Caroline Ran, Elisabet Waldenlind, Christina Sjöstrand, Andrea Carmine Belin
Background The aim of this study was to investigate clinical features of a cluster headache cohort in Sweden and to construct and test a new scale for grading severity. Methods Subjects were identified by screening medical records for the ICD 10 code G44.0, that is, cluster headache. Five hundred participating research subjects filled in a questionnaire including personal, demographic and medical aspects. We constructed a novel scale for grading cluster headache in this cohort: The Cluster Headache Severity Scale, which included number of attacks per day, attack and period duration...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/28901169/predictors-of-response-to-occipital-nerve-stimulation-in-refractory-chronic-headache
#2
Sarah Miller, Laurence Watkins, Manjit Matharu
Background Occipital nerve stimulation is a promising treatment for refractory chronic headache disorders, but is invasive and costly. Identifying predictors of response would be useful in selecting patients. We present the results of an open-label prospective cohort study of 100 patients (35 chronic migraine, 33 chronic cluster headache, 20 short-lasting unilateral neuralgiform headache attacks and 12 hemicrania continua) undergoing occipital nerve stimulation, using a multivariate binary regression analysis to identify predictors of response...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/28899205/non-invasive-vagus-nerve-stimulation-for-the-management-of-refractory-primary-chronic-headaches-a-real-world-experience
#3
Michele Trimboli, Adnan Al-Kaisy, Anna P Andreou, Madeleine Murphy, Giorgio Lambru
Background Non-invasive vagus nerve stimulation has initial evidence of efficacy in migraine and cluster headache. However, little is known about its role in the management of refractory chronic headaches. Methods We evaluated the preventive and abortive effects of non-invasive vagus nerve stimulation in 41 consecutive patients with refractory primary chronic headaches in an open-label prospective clinical audit. Headache diaries were used to collect clinical information. Those who obtained at least 30% reduction in headache days/episodes after three months of treatment were considered responders and were offered treatment continuation...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/28894434/tinnitus-patients-with-comorbid-headaches-the-influence-of-headache-type-and-laterality-on-tinnitus-characteristics
#4
Berthold Langguth, Verena Hund, Michael Landgrebe, Martin Schecklmann
BACKGROUND: Both clinical experience and clinical studies suggest a relationship between tinnitus and headache. Here, we aimed to investigate the influence of comorbid headache type and headache laterality on tinnitus characteristics. METHOD: The Tinnitus Research Initiative database was screened for patients of the Tinnitus Center of the University Regensburg who reported comorbid headaches. These patients were contacted to complete additional validated questionnaires...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/28886860/primary-headache-disorders-part-i-migraine-and-the-trigeminal-autonomic-cephalalgias
#5
Gary W Jay, Robert L Barkin
In Primary Headache Disorders, Part 1, we discuss three of the primary headache disorders using the headache definitions from ICHD-III (Beta): Migraine, with and without aura; its pathophysiology and treatment are discussed. We then discuss the Trigeminal Autonomic Cephalalgias (TACs), including Cluster Headache and Hemicrania Continua, two more primary headache disorders, as well as the other TAC Headaches. We discuss pathophysiology as well as diagnosis, treatment, and pharmacotherapeutic management of these headache diatheses...
September 5, 2017: Disease-a-month: DM
https://www.readbyqxmd.com/read/28883259/naratriptan-may-become-an-alternative-prophylactic-option-for-patients-with-cluster-headache
#6
Shoji Kikui, Takao Takeshima
No abstract text is available yet for this article.
September 6, 2017: Internal Medicine
https://www.readbyqxmd.com/read/28883254/naratriptan-in-the-prophylactic-treatment-of-cluster-headache
#7
Yasuo Ito, Takashi Mitsufuji, Yoshio Asano, Tomokazu Shimazu, Yuji Kato, Norio Tanahashi, Yuichi Maruki, Fumihiko Sakai, Toshimasa Yamamoto, Nobuo Araki
Objective Naratriptan has been reported to reduce the frequency of cluster headache. The purpose of this study was to determine whether naratriptan is effective as a prophylactic treatment for cluster headache in Japan. Methods We retrospectively reviewed all 43 patients with cluster headache who received preventive treatment with naratriptan from April 2009 to April 2015. The International Classification of Headache Disorders, 3rd Edition (beta version) (ICHD-3 beta) was used to diagnose cluster headache. This study was conducted at 3 centers (Department of Neurology, Saitama Medical University; Saitama Neuropsychiatric Institute; Saitama Medical University International Medical Center)...
September 6, 2017: Internal Medicine
https://www.readbyqxmd.com/read/28870224/psychoactive-substances-as-a-last-resort-a-qualitative-study-of-self-treatment-of-migraine-and-cluster-headaches
#8
Martin Andersson, Mari Persson, Anette Kjellgren
BACKGROUND: Treatment resistant cluster headache and migraine patients are exploring alternative treatments online. The aim of this study was to improve comprehension regarding the use of non-established or alternative pharmacological treatments used by sufferers of cluster headaches and migraines. METHODS: A qualitative thematic analysis of the users' own accounts presented in online forum discussions were conducted. The forum boards https://shroomery.org/ , http://bluelight...
September 5, 2017: Harm Reduction Journal
https://www.readbyqxmd.com/read/28857642/cerebral-hemodynamics-in-the-different-phases-of-migraine-and-cluster-headache
#9
Jakob M Hansen, Christoph J Schankin
Headache is one of the most common ailments; migraine is one of the most prevalent and disabling neurological disorders and cluster headache presents as one of the most excruciating pain disorders. Both are complex disorder characterized by recurrent episodes of headache. A key feature is that various triggers can set off an attack providing the opportunity to explore disease mechanisms by experimentally inducing attacks. This review summarizes neuroimaging and hemodynamic studies in human in provoked and spontaneous attacks of migraine and cluster headache...
January 1, 2017: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/28857152/prescribing-oxygen-for-cluster-headache-a-guide-for-the-provider
#10
Stewart J Tepper, Jessica Duplin, Barbara Nye, Deborah E Tepper
BACKGROUND: Oxygen is the standard of care for acute treatment of cluster headache. CMS, the US Centers for Medicaid and Medicare Services, has made the indefensible decision to not cover oxygen for cluster headache for patients with Medicaid and Medicare insurance, despite the evidence and professional guidelines. Commercial insurance generally covers oxygen for cluster headache. OBJECTIVE: This is a "how-to" guide for successfully prescribing oxygen in the US...
August 30, 2017: Headache
https://www.readbyqxmd.com/read/28856479/calcitonin-gene-related-peptide-antagonism-and-cluster-headache-an-emerging-new-treatment
#11
REVIEW
Håkan Ashina, Lawrence Newman, Sait Ashina
Calcitonin gene-related peptide (CGRP) is a key signaling molecule involved in migraine pathophysiology. Efficacy of CGRP monoclonal antibodies and antagonists in migraine treatment has fueled an increasing interest in the prospect of treating cluster headache (CH) with CGRP antagonism. The exact role of CGRP and its mechanism of action in CH have not been fully clarified. A search for original studies and randomized controlled trials (RCTs) published in English was performed in PubMed and in ClinicalTrials...
August 30, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28844048/traumatic-brain-injury-dry-eye-and-comorbid-pain-diagnoses-in-us-veterans
#12
Charity J Lee, Elizabeth R Felix, Roy C Levitt, Christopher Eddy, Elizabeth A Vanner, William J Feuer, Constantine D Sarantopoulos, Anat Galor
AIMS: The purpose of the study is to evaluate the relationship between dry eye (DE) and pain diagnoses in US veterans with and without traumatic brain injury (TBI). METHODS: Retrospective cohort study of veterans who were seen in the Veterans Administration Hospital (VA) between 1 January 2010 and 31 December 2014. Veterans were separated into two groups by the presence or absence of an International Classification of Diseases, Ninth Revision diagnosis of TBI and assessed for DE and other comorbidities...
August 26, 2017: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/28842974/economics-of-inhaled-oxygen-use-as-an-acute-therapy-for-cluster-headache-in-the-united-states-of-america
#13
Megan O'Brien, Janet H Ford, Sheena K Aurora, Sriram Govindan, Deborah E Tepper, Stewart J Tepper
BACKGROUND: Cluster headache (CH) is a primary headache disorder associated with low levels of diagnosis and high unmet medical need. The pain attacks, associated anxiety, and fear in anticipation of the attacks are extremely debilitating to a patient with CH. For acute therapy, treatment guidelines recommend inhalation of high flow oxygen during the period of an attack. However, the use of oxygen for treatment of CH remains largely underutilized. OBJECTIVES: The objectives of the study, which covered each of the US states, were to map the current market landscape of medical grade oxygen for use in CH and to develop a cost simulator based on a patient's needs and geography...
August 26, 2017: Headache
https://www.readbyqxmd.com/read/28831700/screening-of-genetic-variants-in-adcyap1r1-mme-and-14q21-in-a-swedish-cluster-headache-cohort
#14
Caroline Ran, Carmen Fourier, Julia M Michalska, Anna Steinberg, Christina Sjöstrand, Elisabet Waldenlind, Andrea Carmine Belin
BACKGROUND: We have genotyped a Swedish cluster headache case-control population for three genetic variants representing the most significant markers identified in a recently published genome wide association study on cluster headache. The genetic variants were two common polymorphisms; rs12668955 in ADCYAP1R1 (adenylate cyclase activating polypeptide 1 receptor type 1), rs1006417, an intergenic variant on chromosome 14q21 and one rare mutation, rs147564881, in MME (membrane metalloendopeptidase)...
August 22, 2017: Journal of Headache and Pain
https://www.readbyqxmd.com/read/28816505/pre-attack-signs-and-symptoms-in-cluster-headache-characteristics-and-time-profile
#15
Agneta Snoer, Nunu Lund, Rasmus Beske, Rigmor Jensen, Mads Barloese
Introduction In contrast to the premonitory phase of migraine, little is known about the pre-attack (prodromal) phase of a cluster headache. We aimed to describe the nature, prevalence, and duration of pre-attack symptoms in cluster headache. Methods Eighty patients with episodic cluster headache or chronic cluster headache, according to ICHD-3 beta criteria, were invited to participate. In this observational study, patients underwent a semi-structured interview where they were asked about the presence of 31 symptoms/signs in relation to a typical cluster headache attack...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/28815720/pharmacological-evidence-of-involvement-of-nitric-oxide-pathway-in-anti-pruritic-effects-of-sumatriptan-in-chloroquine-induced-scratching-in-mice
#16
Nazgol-Sadat Haddadi, Sattar Ostadhadi, Saeed Shakiba, Khashayar Afshari, Nastaran Rahimi, Arash Foroutan, Ahmad-Reza Dehpour
Chloroquine (CQ) induces histamine-independent itch in human and mice. We recently reported the role of intradermal nitric oxide (NO)/ cyclic guanosine monophosphate (cGMP) pathway in CQ-evoked scratching in mice. Chloroquine stimulates neuronal nitric oxide synthase (nNOS) activity to over-producing NO in the skin. Sumatriptan, a 5-hydroxytryptamine 1b/1d receptors (5-HTR1b/1d) agonist, is involved in pain and used to treat migraine and cluster headaches. According to previous studies, sumatriptan inhibits NOS activity...
August 16, 2017: Fundamental & Clinical Pharmacology
https://www.readbyqxmd.com/read/28765481/carotid-dissection-presenting-as-a-prolonged-cluster-like-headache-in-a-patient-with-episodic-cluster-headache
#17
Ahmed Mohamed Elhfnawy, László Solymosi, Claudia Sommer
We present a patient with known episodic cluster headache, who presented with cluster-like headache in the course of internal carotid artery dissection (ICAD) and discuss possible pathophysiological links between the two diseases. It is well known that cluster-like headache could be the presenting symptom of ICAD. However, ICAD occurring in a patient with a known episodic cluster headache was only once previously described. In the end of the manuscript, we propose red flags to help clinicians differentiate between primary cluster headache and cluster-like attacks masking underlying ICAD...
July 31, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28741257/the-comorbidity-burden-of-patients-with-cluster-headache-a-population-based-study
#18
Shivang Joshi, Paul Rizzoli, Elizabeth Loder
BACKGROUND: Evidence is limited regarding the comorbidity burden of patients with cluster headache (CH). We aimed to characterize comorbid conditions in a cohort of CH patients diagnosed by headache experts, using electronic health record information from the Partners Research Patient Data Registry (RPDR). METHODS: We identified and reviewed the charts of unique patients diagnosed by headache specialists over an 11-year period, and a set of matched controls. Patients were categorized as having Definite, Unconfirmed or no CH...
December 2017: Journal of Headache and Pain
https://www.readbyqxmd.com/read/28739219/systematic-review-of-hardware-related-complications-of-deep-brain-stimulation-do-new-indications-pose-an-increased-risk
#19
Onanong Jitkritsadakul, Roongroj Bhidayasiri, Suneil K Kalia, Mojgan Hodaie, Andres M Lozano, Alfonso Fasano
INTRODUCTION: Deep Brain Stimulation (DBS) is an effective treatment extended broadly to many neurological and psychiatric disorders. Nevertheless, complications may arise during DBS procedures or following implantation due to implanted hardware. This may result in both minor and major adverse events that may necessitate hardware removal and/or compromise maximal therapeutic benefit for the patient. OBJECTIVES AND METHODS: To identify relevant literature on hardware-related complications from DBS procedures by performing a systematic review, and propose how to identify at-risk group and possible preventive approaches...
July 13, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28734941/sleep-chronic-pain-and-opioid-risk-for-apnea
#20
REVIEW
Serguei Marshansky, Pierre Mayer, Dorrie Rizzo, Marc Baltzan, Ronald Denis, Gilles J Lavigne
Pain is an unwelcome sleep partner. Pain tends to erode sleep quality and alter the sleep restorative process in vulnerable patients. It can contribute to next-day sleepiness and fatigue, affecting cognitive function. Chronic pain and the use of opioid medications can also complicate the management of sleep disorders such as insomnia (difficulty falling and/or staying asleep) and sleep-disordered breathing (sleep apnea). Sleep problems can be related to various types of pain, including sleep headache (hypnic headache, cluster headache, migraine) and morning headache (transient tension type secondary to sleep apnea or to sleep bruxism or tooth grinding) as well as periodic limb movements (leg and arm dysesthesia with pain)...
July 19, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
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