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https://www.readbyqxmd.com/read/28076021/radiologic-assessment-of-native-renal-vasculature-a-multimodality-review
#1
Sayf Al-Katib, Monisha Shetty, Syed Mohammad A Jafri, Syed Zafar H Jafri
A wide range of clinically important anatomic variants and pathologic conditions may affect the renal vasculature, and radiologists have a pivotal role in the diagnosis and management of these processes. Because many of these entities may not be suspected clinically, renal artery and vein assessment is an essential application of all imaging modalities. An understanding of the normal vascular anatomy is essential for recognizing clinically important anatomic variants. An understanding of the protocols used to optimize imaging modalities also is necessary...
January 2017: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/28074298/effect-of-intraoperative-radiotherapy-in-the-treatment-of-retroperitoneal-sarcoma
#2
Liz B Wang, David McAneny, Gerard Doherty, Teviah Sachs
BACKGROUND: Current National Comprehensive Cancer Network guidelines for the treatment of retroperitoneal sarcomas (RPS) endorse surgical resection, but the role of radiotherapy (RT) is less clear. We investigate the utilization and benefits of intraoperative RT (IORT) in the treatment of RPS. METHODS: We queried the Surveillance, Epidemiology and End Results (SEER) database (1988-2013) for the utilization of IORT and perioperative external beam RT (EBRT) in patients who underwent surgical resection of RPS...
January 10, 2017: International Journal of Clinical Oncology
https://www.readbyqxmd.com/read/28066666/ct-guided-percutaneous-microwave-ablation-of-pulmonary-malignant-tumors
#3
Wei-Chun Ko, Yee-Fan Lee, Yi-Chang Chen, Ning Chien, Yu-Sen Huang, Yao-Hui Tseng, Jang-Ming Lee, Hsao-Hsun Hsu, Jin-Shing Chen, Yeun-Chung Chang
BACKGROUND: Microwave ablation (MWA) of lung tumors is a new approach for local tumor control. The purpose of this retrospective study was to evaluate the preliminary results of safety and efficacy of MWA with a dynamic frequency range (902-928 MHz) and power (10-32 W) for local tumor control of thoracic malignancies. METHODS: From December 1, 2013 to February 1, 2016, there were total 32 lung tumors among 15 patients (7 men, 8 women, age range 43-82 years, mean 57...
October 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28065534/laparoscopically-assisted-resection-of-a-primary-hepatic-leiomyosarcoma-a-safe-approach-in-a-rare-malignancy
#4
Víctor López-López, Ricardo Robles, Belén Ferri, Roberto Brusadin, Pascual Parrilla
No abstract text is available yet for this article.
January 5, 2017: Cirugía Española
https://www.readbyqxmd.com/read/28064296/the-follow-up-of-post-mastectomy-patients-should-the-ipsilateral-side-be-assessed-with-both-mammogram-and-ultrasound
#5
S Radhika, B Hartini, A Norlia, M P Suria-Hayati, M A Zulfiqar
AIM: This study aimed to determine findings of axillary view mammogram (MMG) and ultrasound (USG) of the ipsilateral side in post-mastectomy patients and to document difficulty level in performing the axillary view and patients' pain level during the procedure. METHODS: Post-mastectomy patients who had MMG and USG on follow-up during an 18-months period were included. The MMG and USG findings of 183 patients were reviewed and histology results were recorded when available...
October 2016: Medical Journal of Malaysia
https://www.readbyqxmd.com/read/28058942/chronic-paroxysmal-headache-secondary-to-an-orbital-metastatic-leiomyosarcoma-a-case-report
#6
Hyun Ah Choi, Mi Ji Lee, Chin-Sang Chung
Background Intraorbital lesions associated with symptomatic trigeminal autonomic cephalalgias (TACs) are rarely reported. We present a case of orbital metastatic leiomyosarcoma, presenting with chronic paroxysmal hemicrania-like headache. Case report A 43-year-old man presented with a severe paroxysmal headache in his left periocular and frontal area for a year. The attacks occurred 10-12 times per day, lasting 10-15 minutes with ipsilateral lacrimation and conjunctival injection. Neurological examination and brain MRI without contrast were unremarkable...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/28057392/primary-retroperitoneal-soft-tissue-sarcoma-imaging-appearances-pitfalls-and-diagnostic-algorithm
#7
REVIEW
C Messiou, E Moskovic, D Vanel, C Morosi, R Benchimol, D Strauss, A Miah, H Douis, W van Houdt, S Bonvalot
Although retroperitoneal sarcomas are rare tumours, they can be encountered by a wide variety of clinicians as they can be incidental findings on imaging or present with non specific symptoms and signs. Surgical resection can offer hope of cure and patient outcomes are improved when patients are managed in high-volume specialist centers. Failure to recognize retroperitoneal sarcomas on imaging can lead to inappropriate management in inexperienced centers. Therefore it is critical that a diagnosis of retroperitoneal sarcoma should be considered in the differential diagnosis of a retroperitoneal mass with prompt referral to a soft tissue sarcoma unit...
December 9, 2016: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28050004/interstitial-lung-disease-induced-by-pazopanib-treatment
#8
Shotaro Ide, Noriho Sakamoto, Shintaro Hara, Atsuko Hara, Tomoyuki Kakugawa, Yoichi Nakamura, Yoji Futsuki, Koichi Izumikawa, Yuji Ishimatsu, Katsunori Yanagihara, Hiroshi Mukae
Although pneumothorax has been reported to be a major pulmonary adverse event in patients treated with pazopanib, a multikinase inhibitor, drug-induced interstitial lung disease (DILD) has not been reported. A 74-year-old Japanese man who received pazopanib for the treatment of femoral leiomyosarcoma and lung metastasis presented with dyspnea and fatigue. He had mild interstitial pneumonia when pazopanib treatment was initiated. Chest computed tomography revealed progressive bilateral ground-glass opacity (GGO) and traction bronchiectasis...
2017: Internal Medicine
https://www.readbyqxmd.com/read/28048896/su-f-t-03-radiobiological-evaluation-of-a-directional-brachytherapy-device-surgically-implanted-following-ebrt
#9
M J Rivard, J G Emrich, J Poli
PURPOSE: Preceding surgical implantation following external-beam radiotherapy (EBRT) delivery, a radiobiological evaluation was performed for a new LDR Pd-103 directional brachytherapy device (CivaSheet). As this was the first case with the device used in combination with EBRT, there was concern to determine the appropriate prescription dose. METHODS: The radiobiological model of Dale (1985, 1989) was used for a permanent LDR implant including radioactive decay...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28032292/leiomyosarcoma-involving-the-pancreas-diagnosed-by-endoscopic-ultrasound-fine-needle-aspiration
#10
Mohamed Abdelfatah, Eric M Gochanour
No abstract text is available yet for this article.
December 29, 2016: Journal of Gastrointestinal Cancer
https://www.readbyqxmd.com/read/28027201/incidence-and-clinical-features-of-rare-cutaneous-malignancies-in-olmsted-county-minnesota-2000-to-2010
#11
Stanislav N Tolkachjov, Adam R Schmitt, John G Muzic, Amy L Weaver, Christian L Baum
BACKGROUND: The incidence of rare cutaneous malignancies is unknown. Current estimates of rare cutaneous malignancy incidences are based on broad epidemiologic data or single institution experiences, not population-based data. OBJECTIVE: To determine the incidence of several rare nonmelanoma skin cancers. MATERIALS AND METHODS: The authors conducted a retrospective chart review of a population-based cohort between the years 2000 and 2010. Residents of Olmsted County, Minnesota, who were diagnosed with a biopsy-proven nonmelanoma skin cancer-excluding basal cell carcinoma and squamous cell carcinoma-were included in this study...
January 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28018091/primary-leiomyosarcoma-of-femur
#12
Nishit Bhatnagar, Purushotham Lingaiah, Anurag Tiwari, Nidhi Mahajan, Sumit Arora, Anil Dhal
Primary leiomyosarcoma of the bone is exceedingly rare. In this case, we describe a middle-aged female with a primary leiomyosarcoma of the distal femur. The patient was treated by hip disarticulation. The patient continues to be disease-free at one-year follow-up.
October 2016: Journal of Clinical Orthopaedics and Trauma
https://www.readbyqxmd.com/read/28011357/prognostic-differences-epstein-barr-virus-associated-primary-leiomyosarcoma-of-the-spine-versus-spinal-leiomyosarcoma-metastases
#13
REVIEW
Nitin Agarwal, David R Hansberry, Ami Kavi, Prateek Agarwal, Ada Baisre, Ira M Goldstein
The authors present six cases of osseous leiomyosarcoma of the spine. Two of these cases are of immunocompromised human immunodeficiency virus (HIV) positive patients with Epstein-Barr virus (EBV) associated primary vertebral leiomyosarcomas. The remaining four cases are of patients with leiomyosarcoma metastases to the spine. Each patient underwent surgical resection of their vertebral mass; however, the patients with the EBV associated tumors had the best postoperative prognosis. The HIV-positive patients have had no further local recurrence, while the other four patients had rapid local recurrences requiring multiple surgical interventions...
December 21, 2016: World Neurosurgery
https://www.readbyqxmd.com/read/28009608/fosb-is-a-useful-diagnostic-marker-for-pseudomyogenic-hemangioendothelioma
#14
Yin P Hung, Christopher D M Fletcher, Jason L Hornick
Pseudomyogenic (epithelioid sarcoma-like) hemangioendothelioma is a distinctive vascular neoplasm of intermediate biological potential with a predilection for young adults and frequent multifocal presentation. Pseudomyogenic hemangioendothelioma is characterized by loose fascicles of plump spindled and epithelioid cells with abundant eosinophilic cytoplasm and coexpression of keratins and endothelial markers. Recently, a SERPINE1-FOSB fusion has been identified as a consistent genetic alteration in pseudomyogenic hemangioendothelioma...
December 22, 2016: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28007271/biatrial-high-grade-leiomyosarcoma-with-nine-year-post-surgical-survival
#15
Lakshmi Muthukumar, M Fuad Jan, Robert Taylor, John Crouch, Gary Neitzel, A Jamil Tajik
Primary cardiac leiomyosarcoma is a rare tumor with poor prognosis. We present a 53-year-old female patient with biatrial leiomyosarcoma with inferior vena cava and coronary sinus involvement who underwent aggressive surgical resection with reconstruction of her left and right atrium and coronary sinus with bovine pericardium followed by adjuvant radiation therapy. She is living well with no recurrence 9 years after diagnosis.
January 2017: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/28004137/abdominal-wall-endometriosis-differentiation-from-other-masses-using-ct-features
#16
Gail Yarmish, Evis Sala, Debra A Goldman, Yulia Lakhman, Robert A Soslow, Hedvig Hricak, Ginger J Gardner, H Alberto Vargas
PURPOSE: To assess the utility of morphologic and quantitative CT features in differentiating abdominal wall endometriosis (AWE) from other masses of the abdominal wall. METHODS: Retrospective IRB-approved study of 105 consecutive women from two institutions who underwent CT and biopsy/resection of abdominal wall masses. CTs were independently reviewed by two radiologists blinded to final histopathologic diagnoses. Associations between CT features and pathology were tested using Fisher's Exact Test...
December 21, 2016: Abdominal Radiology
https://www.readbyqxmd.com/read/28004108/potential-role-of-bcl2-in-the-recurrence-of-uterine-smooth-muscle-tumors-of-uncertain-malignant-potential
#17
Donatella Conconi, Valentina Chiappa, Patrizia Perego, Serena Redaelli, Giorgio Bovo, Marialuisa Lavitrano, Rodolfo Milani, Leda Dalprà, Andrea Alberto Lissoni
Uterine smooth muscle tumors are the most common female genital tract neoplasms. While leiomyosarcoma has been studied at length, smooth muscle tumors of uncertain malignant potential (STUMPs) still have ambiguous and unresolved issues, with a risk of relapse and evolution largely undefined. We performed an array comparative genomic hybridization analysis on a primitive STUMP and its local recurrence, histologically diagnosed as undifferentiated sarcoma. To the best of our knowledge, our report is the first genomic study on primitive STUMPs and the different relapsed tumors...
January 2017: Oncology Reports
https://www.readbyqxmd.com/read/28002802/dual-inhibition-of-the-pi3k-akt-mtor-pathway-suppresses-the-growth-of-leiomyosarcomas-but-leads-to-erk-activation-through-mtorc2-biological-and-clinical-implications
#18
Benjamin Fourneaux, Vanessa Chaire, Carlo Lucchesi, Marie Karanian, Raphael Pineau, Audrey Laroche-Clary, Antoine Italiano
The PI3K/AKT/mTOR pathway plays a crucial role in the development of leiomyosarcomas (LMSs). In this study, we tested the efficacy of dual PI3K/mTOR (BEZ235), PI3K (BKM120) and mTOR (everolimus) inhibitors in three human LMS cell lines. In vitro and in vivo studies using LMS cell lines showed that BEZ235 has a significantly higher anti-tumor effect than either BKM120 or everolimus, resulting in a greater reduction in tumor growth and more pronounced inhibitory effects on mitotic activity and PI3K/AKT/mTOR signaling...
December 16, 2016: Oncotarget
https://www.readbyqxmd.com/read/28002210/european-society-of-gynecological-oncology-statement-on-fibroid-and-uterine-morcellation
#19
Michael J Halaska, Dimitrios Haidopoulos, Frédéric Guyon, Philippe Morice, Ignacio Zapardiel, Vesna Kesic
Recently, there has been an intense discussion about the issue of fibroid and uterine morcellation in relation to the risk of unrecognized uterine sarcoma spread. Morcellation can negatively influence the prognosis of patients, and transecting the specimen into pieces prevents the pathologist from performing proper disease staging. Many societies have published their statements regarding this issue. The European Society for Gynecological Oncology has established a working group of clinicians involved in diagnostics and treatment of oncogynecological patients to provide a statement from the oncological point of view...
January 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/27997438/diffusion-weighted-imaging-for-differentiating-uterine-leiomyosarcoma-from-degenerated-leiomyoma
#20
Hai Ming Li, Jia Liu, Jin Wei Qiang, Hao Zhang, Guo Fu Zhang, FengHua Ma
PURPOSE: The study aimed to investigate magnetic resonance diffusion-weighted imaging (DWI) in the differentiation of uterine leiomyosarcoma (ULMS) from degenerated leiomyoma (DLM). METHODS: Sixteen patients with ULMSs and 26 patients with DLMs confirmed by surgery and pathology underwent conventional magnetic resonance imaging and DWI. The mean apparent diffusion coefficient (ADC) values of the 2 groups' tumors were measured and compared using an independent-sample t test (b = 0...
December 15, 2016: Journal of Computer Assisted Tomography
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