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boundary violations regulation

Takahiro Kohsokabe, Kunihiko Kaneko
Search for possible relationships between phylogeny and ontogeny is important in evolutionary-developmental biology. Here we uncover such relationships by numerical evolution and unveil their origin in terms of dynamical systems theory. By representing developmental dynamics of spatially located cells with gene expression dynamics with cell-to-cell interaction under external morphogen gradient, gene regulation networks are evolved under mutation and selection with the fitness to approach a prescribed spatial pattern of expressed genes...
January 2016: Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution
Emma Lough, Mary Hanley, Jacqui Rodgers, Mikle South, Hannah Kirk, Daniel P Kennedy, Deborah M Riby
Interpersonal distance regulation is crucial for successful social interactions. We investigated personal space awareness in Williams syndrome (WS) and autism spectrum disorder (ASD) compared to typical development. Parents reported that individuals with WS and ASD were significantly more likely than those developing typically to invade the personal space of others. WS individuals were reported to have the least awareness of the personal space boundaries of others. Despite the suggested opposing social profiles of WS and ASD, some similarities are present in the ability, or indeed inability, to regulate interpersonal distance during social interactions...
December 2015: Journal of Autism and Developmental Disorders
Joseph C d'Oronzio
No abstract text is available yet for this article.
May 2015: AMA Journal of Ethics
Dirk De Vos, Kris Vissenberg, Jan Broeckhove, Gerrit T S Beemster
In recent years there has been a strong development of computational approaches to mechanistically understand organ growth regulation in plants. In this study, simulation methods were used to explore which regulatory mechanisms can lead to realistic output at the cell and whole organ scale and which other possibilities must be discarded as they result in cellular patterns and kinematic characteristics that are not consistent with experimental observations for the Arabidopsis thaliana primary root. To aid in this analysis, a 'Uniform Longitudinal Strain Rule' (ULSR) was formulated as a necessary condition for stable, unidirectional, symplastic growth...
October 2014: PLoS Computational Biology
Anita Catlin
This article considers the ethics of boundaries and nursing practice. The nurse's role as a "carer" is reflected in the context of boundary setting, boundary crossing, and boundary violation. This issue is redeveloped within the new perspective of the nurse's use of social media and boundary crossing. National and international regulations are discussed and individual cases assessed. The Nurses Code of Ethics is used as a framework. The American Nurses Association material on social media is reviewed.
October 2013: Advances in Neonatal Care: Official Journal of the National Association of Neonatal Nurses
F Stuart Kinsinger, Wendy Sutton
Health practitioners work under fiduciary constraint, and are obligated to favour patient needs over all others and in particular their own. The principles of professionalism demand that professionals take great care to ensure that boundaries are maintained safely to provide an optimal setting in facilitating patient care. Boundary violations cause serious harm to the patient. Any romantic or sexual activity between parties is the most serious form of boundary violation. The chiropractic profession is included in the list of disciplines which are at an increased risk for boundary violations...
March 2012: Journal of the Canadian Chiropractic Association
Gonzalo Herranz Rodríguez
The phenomenon of ethically deficient publication in the field of bioethics is practically unknown. In contrast to the numerous articles and regulations on the ethics of biomedical publications, there is a practical absence of articles devoted to consider the nature, types and prevalence of ethically defective publications in the bioethical literature. No regulatory framework for misbehavior in this field has been proposed until now. Certainly, this is a difficult subject. On one side, it is not easy to draw the ethical limits of the freedoms of thought and expression in bioethics, a discipline that flourishes in the open debate of principles, norms, cases, and imaginary scenarios, where the boundaries between rhetoric and misrepresentation are frequently blurred...
May 2011: Cuadernos de Bioética: Revista Oficial de la Asociación Española de Bioética y Ética Médica
Kyoko Tossell, Laura C Andreae, Chloe Cudmore, Emily Lang, Uma Muthukrishnan, Andrew Lumsden, Jonathan D Gilthorpe, Carol Irving
The midbrain-hindbrain boundary (MHB) acts as an organiser/signalling centre to pattern tectal and cerebellar compartments. Cells in adjacent compartments must be distinct from each other for boundary formation to occur at the interface. Here we have identified the leucine-rich repeat (LRR) neuronal 1 (Lrrn1) protein as a key regulator of this process in chick. The Lrrn family is orthologous to the Drosophila tartan/capricious (trn/caps) family. Differential expression of trn/caps promotes an affinity difference and boundary formation between adjacent compartments in a number of contexts; for example, in the wing, leg and eye imaginal discs...
April 15, 2011: Developmental Biology
Tamara Hew-Butler
The ability of the human body to regulate plasma osmolality (POsm) within a very narrow and well defined physiological range underscores the vital importance of preserving water and sodium balance at rest and during exercise. The principle endocrine regulator of whole body fluid homeostasis is the posterior pituitary hormone, arginine vasopressin (AVP). Inappropriate AVP secretion may perpetuate either slow or rapid violation of these biological boundaries, thereby promoting pathophysiology, morbidity and occasional mortality...
June 1, 2010: Sports Medicine
Andrew Crowden
The moral status of professional boundaries and the ethical nature of dual and multiple overlapping human relationships in contemporary clinical practice remain enduring problems in all health care disciplines. In this paper I explore the ethics of dual or multiple overlapping relationship and apply a virtue ethics framework to the case of psychotherapy. After clarifying the context and meaning of commonly used terminology, and considering what some of the key Australian codes of ethics relevant to psychotherapy advise about dual relationships, I identify some commonly occurring situations where overlapping relationships are unavoidable...
October 2008: Monash Bioethics Review
Geoff Neimark
Regulation of the interstate practice of medicine represents a challenge to state medical boards. Although laws prohibiting the unlicensed practice of medicine were originally enacted to protect the public from unqualified practitioners, they could be invoked in a whole host of common clinical situations such as calling in prescriptions to a patient in another state, giving expert testimony in another jurisdiction, or reviewing radiology films on the internet, with potentially serious criminal ramifications...
2009: Journal of the American Academy of Psychiatry and the Law
Holly R Fischer, Betsy J Houchen, Lisa Ferguson-Ramos
This article provides case studies in professional boundaries violations from a state regulatory perspective. All cases discussed are actual cases that occurred in the state of Ohio, based on complaints investigated by the Ohio Board of Nursing. The studies set forth basic factual information related to the boundary violation, relevant law and administrative regulations, and disciplinary outcomes. One can conclude that boundaries violations that result in licensure board disciplinary sanctions typically involve gross or egregious conduct rather than subtle or transitional zone conduct...
October 2008: Nursing Administration Quarterly
Vinod Goel, Raymond J Dolan
The element of surprise, a necessary condition for the experience of humor, often derives from the fact that the alternative interpretation/resolution offered by the punch line of a joke is physically or socially forbidden. Children's humor typifies violation of physical norms, whereas adult humor typically pushes the boundaries of social norms. Excess norm violation, to the point of offending, can attenuate the experience of humor/mirth. To examine the neural basis of regulation of affective experience of humor by social norms, we scanned 16 normal subjects while they viewed a series of cartoons that varied in funniness and social acceptability...
September 2007: Journal of Cognitive Neuroscience
Rene Geanellos
A large volume of literature exists on childhood sexual abuse (CSA) and nursing literature on this topic continues to develop. However, discussion of boundaries in relation to intrafamilial childhood sexual abuse (ICSA) and to its significance in terms of personal space boundary (PSB) violation, is lacking. This is important, as PSB violation creates difficulties for adult survivors of ICSA and for nurses who care for these people as clients. As all experiences of CSA cannot be addressed, discussion focuses on women who are clients of mental health services and who have experienced ICSA...
September 2003: International Journal of Mental Health Nursing
David M Braun, Yi Ma, Noriko Inada, Michael G Muszynski, R Frank Baker
Acquisition of cell identity requires communication among neighboring cells. To dissect the genetic pathways regulating cell signaling in later leaf development, a screen was performed to identify mutants with chloroplast pigmentation sectors that violate cell lineage boundaries in maize (Zea mays) leaves. We have characterized a recessive mutant, tie-dyed1 (tdy1), which develops stable, nonclonal variegated yellow and green leaf sectors. Sector formation requires high light, occurs during a limited developmental time, and is restricted to leaf blade tissue...
December 2006: Plant Physiology
Harry W Schroeder
Over the past twenty years diverse groups in Northeast Asia, Western Europe, and North America have competed to map, sequence, and characterize the immunoglobulin loci of mouse and man. Now that this work is near completion, it has become evident that the human and mouse germline repertoires share broad similarities in gene composition, organization, and other general principles. In spite of these similarities, the repertoires expressed by adult mice and humans are distinct and differ from each other in detail...
2006: Developmental and Comparative Immunology
Lee H Beecher, Steven I Altchuler
Health services professionals agree that sexual relations between treating clinicians and their patients are harmful and should not be tolerated. Minnesota law and regulations encourage identification of offending clinicians in order to protect the public. Regulatory agencies such as the Minnesota Board of Medical Practice seek to stop licensed professionals from engaging in sexual behavior with patients and also, when feasible, to restore medical professionals to competent practice. The authors recommend individualized psychiatric assessment and therapy for physicians who violate professional standards...
June 2005: Minnesota Medicine
A M Neliudova, A I Brichkina, M P Rukhlova, N D Aksenov, T V Pospelova
E1A + c-Ha-ras-transformants overexpressing bcl-2 oncogene are able to be arrested at the G1/S boundary of the cell cycle after DNA damage and upon serum starvation, this cell cycle blockage being accompanied by a decrease in the activity of cyclin E--Cdk2 complexes. Roscovitine-induced inhibition of cyclin-dependent kinases (Cdks) activity does not result in the G1/S arrest of E1A + c-Ha-ras + bcl-2-transformants. Roscovitine treatment causes an accumulation of G2/M cells, mainly at the expense of mitotic cells...
2004: Tsitologiia
Mark Eddison, Leah Toole, Esther Bell, Richard J T Wingate
BACKGROUND: Cerebellar granule cell precursors are specifically generated within the hindbrain segment, rhombomere 1, which is bounded rostrally by the midbrain/hindbrain isthmus and caudally by the boundary of the Hoxa2 expression domain. While graded signals from the isthmus have a demonstrable patterning role within this region, the significance of segmental identity for neuronal specification within rhombomere 1 is unexplored. We examined the response of granule cell precursors to the overexpression of Hoxa2, which normally determines patterns of development specific to the hindbrain...
2004: BMC Biology
A E Shamoo
NIH data indicate that annually seven million human subjects are enrolled in research sponsored by NIH alone. In addition, there are sixteen federal agencies and numerous departments outside NIH conducting experiments with human subjects. Moreover, the pharmaceutical industry spends $26 billion on research (compared to $16 billion for NIH), thus, the total number of human subjects enrolled in research for both the public and private sectors can be estimated as high as nineteen million. I present data on the potential magnitude of adverse events in the United States among human subjects enrolled in research that appear to be unreported and unaccounted for...
2001: Accountability in Research
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