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https://www.readbyqxmd.com/read/28441303/surgical-techniques-for-closure-of-a-scalp-defect-after-resection-of-skin-malignancy
#1
Maciej Rysz, Dariusz Grzelecki, Maciej Mazurek, Stanisław Starościak, Romuald Krajewski
BACKGROUND: Surgery for scalp malignancies is aimed at the complete resection and a good aesthetic outcome. The goal was to develop an algorithm for scalp reconstruction based on the authors' surgical experience. METHODS: This is a retrospective analysis of 123 procedures of scalp malignancies in 105 patients. Twenty eight procedures were for resection of squamous cell carcinoma, 54 for basal cell carcinoma, and 41 for suspected melanomas. RESULTS: Primary closure (27 procedures), local flap (LF; 19), split-thickness skin graft (SG; 64), rotated LF and SG (9), and free vascularized flaps (4) were used...
May 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28440741/standardized-rat-model-testing-effects-of-inflammation-and-grafting-on-extraction-healing
#2
Emily S Willett, Jingpeng Liu, Molly Berke, Peter J Giannini, Marian Schmid, Zhenshan Jia, Xiaobei Wang, Xiaoyan Wang, Kaeli Samson, Fang Yu, Dong Wang, Ali Nawshad, Richard A Reinhardt
BACKGROUND: Loss of the alveolar ridge width and height following tooth extraction is well-documented, but models to evaluate ridge preservation are neither standardized nor cost-effective. This rat model characterizes the pattern of bone turnover and inflammation after extraction and bone grafting with or without local simvastatin (SIM). METHODS: Fifty retired-breeder rats underwent extraction of the right maxillary first molar and standard surgical defect creation under inhalation/local anesthesia...
April 25, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28439635/high-incidence-of-partially-anatomic-tunnel-placement-in-primary-single-bundle-acl-reconstruction
#3
Andrea Achtnich, Francesco Ranuccio, Lukas Willinger, Jonas Pogorzelski, Andreas B Imhoff, Sepp Braun, Elmar Herbst
PURPOSE: The purpose of this study was to evaluate tunnel position and width in failed primary single-bundle (SB) anterior cruciate ligament (ACL) reconstructions. It was hypothesized that both femoral and tibial bone tunnels are frequently malplaced in terms of a partially anatomic position in the setting of failed SB ACL reconstruction. METHODS: Patients with recurrent instability following isolated SB ACL reconstruction using hamstring tendon autografts, undergoing revision ACL surgery, were retrospectively included...
April 24, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28439305/costal-cartilage-transplantation-for-treatment-of-growth-plate-injury-in-a-rabbit-model
#4
D Otsuki, K Yoshida, M Kobayashi, D Hamano, C Higuchi, H Yoshikawa
OBJECTIVES: The purpose of this study is to evaluate the effects of allogenic costal cartilage transplantation on preventing bony bridge formation and angular deformities for the treatment of partial growth plate injury using a rabbit model. METHODS: An experimental model of partial growth injury was created by resecting the medial part of the proximal tibial growth plate in male six-week-old New Zealand White rabbits. The rabbits were divided into four groups: no surgery; no transplantation; bone wax transplantation; and allogenic costal cartilage transplantation...
2017: Journal of Children's Orthopaedics
https://www.readbyqxmd.com/read/28439172/management-of-chronic-recurrent-dislocation-of-temporomandibular-joint-using-u-shaped-graft-a-new-restrictive-technique
#5
Kiran Gadre, Divya Singh, Pushkar Gadre, Rajshekhar Halli
BACKGROUND: Numerous procedures have been described for the treatment of chronic recurrent dislocation of the temporo-mandibular joint (TMJ), either in the form of enhancement or restriction of the condylar movement, with their obvious merits and demerits. MATERIALS AND METHOD: We present a new technique of using U shaped iliac bone graft to restrict the condylar movement and its advantages over the conventional techniques.We have used this technique successfully in 8 cases where Dautrey's procedure had failed with follow up period of 2 years...
June 2017: Journal of Maxillofacial and Oral Surgery
https://www.readbyqxmd.com/read/28437545/union-knee-alignment-and-clinical-outcomes-of-patients-treated-with-autologous-bone-grafting-for-medial-tibial-defects-in-primary-total-knee-arthroplasty
#6
Kunihiro Hosaka, Shu Saito, Teruyasu Oyama, Hirohisa Fujimaki, Eiji Cho, Kanki Ishigaki, Yasuaki Tokuhashi
Autologous bone grafting is an established method to overcome bone deficiencies in primary total knee arthroplasty (TKA). However, recently, metal augments have been used by many surgeons. Although autologous bone grafting is a common technique, few large studies have described its success in achieving bone union in primary TKA. The goal of this study was to evaluate primary TKA with autologous bone grafting for tibial defects. A total of 68 knees that had undergone arthroplasty with autologous bone grafting with more than 1 year of follow-up were evaluated...
April 24, 2017: Orthopedics
https://www.readbyqxmd.com/read/28437496/novel-solution-for-massive-glenoid-defects-in-shoulder-arthroplasty-a-patient-specific-glenoid-vault-reconstruction-system
#7
David M Dines, Lawrence Gulotta, Edward V Craig, Joshua S Dines
Complex glenoid deformities present the most difficult challenges in shoulder arthroplasty. These deformities may be caused by severe degenerative or congenital deformity, posttraumatic anatomy, tumor, or, in most cases, bone loss after glenoid failure in anatomical total shoulder arthroplasty. Methods of treating severe bone loss have included inlay and onlay bone-graft options with augmented fixation and, in severe cases, salvage hemiarthroplasty with limited goal expectations. Unfortunately, none of these methods has provided consistently satisfactory reproducible results...
March 2017: American Journal of Orthopedics
https://www.readbyqxmd.com/read/28437334/a-new-fixation-technique-for-french-door-cervical-laminoplasty-surgical-results-with-a-minimum-follow-up-of-6-years
#8
Nanjundappa S Harshavardhana, Harshad V Dabke, Hossein Mehdian
DESIGN: A case series of 5 patients with multilevel cervical myelopathy treated by French-door cervical laminoplasty (FDCL) and use of unicortical iliac crest graft as spacer fixed with titanium miniplates and screws is described. OBJECTIVE: To report a minimum of 6-year follow-up results of our new plate-screw fixation technique for FDCL. SUMMARY OF BACKGROUND DATA: Hardware-assisted laminoplasty has the potential advantage of preventing restenosis by holding the laminar door "open" while healing progresses and also prevents spacer dislodgement...
May 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28435918/cost-analysis-of-adolescent-idiopathic-scoliosis-surgery-early-discharge-decreases-hospital-costs-much-less-than-intraoperative-variables-under-the-control-of-the-surgeon
#9
Brandon L Raudenbush, David P Gurd, Ryan C Goodwin, Thomas E Kuivila, R Tracy Ballock
BACKGROUND: Spinal fusion surgery for the treatment of adolescent idiopathic scoliosis (AIS) is increasing. Health systems and surgeons are decreasing hospital length of stay (LOS) to decrease costs. The purpose of this study was to review the contribution of an accelerated discharge protocol on the total cost of a single episode of care related to the surgical treatment of AIS at a single institution. METHODS: A retrospective cost analysis was performed over an 18-month period, from January 2014 through June 2015, before and after the institution of an accelerated discharge program...
March 2017: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/28435697/calcium-phosphates-and-silicon-exploring-methods-of-incorporation
#10
Ana I Rodrigues, Rui L Reis, Clemens A van Blitterswijk, Isabel B Leonor, Pamela Habibović
BACKGROUND: Bioinorganics have been explored as additives to ceramic bone graft substitutes with the aim to improve their performance in repair and regeneration of large bone defects. Silicon (Si), an essential trace element involved in the processes related to bone formation and remodeling, was shown not only to enhance osteoblasts proliferation but also to stimulate the differentiation of mesenchymal stem cells (MSCs) and preosteoblasts into the osteogenic lineage. In this study, the added value of Si to calcium phosphate (CaP) coatings was evaluated...
2017: Biomaterials Research
https://www.readbyqxmd.com/read/28435567/role-of-antibiotic-cement-coated-nailing-in-infected-nonunion-of-tibia
#11
C Bhatia, A K Tiwari, S B Sharma, S Thalanki, A Rai
INTRODUCTION: Infected nonunion of long bones is a chronic and debilitating disorder. It is more difficult to deal with when the implant used for internal fixation itself becomes a potential media for infection because of bacterial adhesion and biofilm formation. Traditionally, it is managed by two-stage procedure for controlling the infection first and then treating the nonunion. This study has been undertaken to explore antibiotic cement coated nailing as single stage treatment modality for treating infection and achieving stability at the same time...
March 2017: Malaysian Orthopaedic Journal
https://www.readbyqxmd.com/read/28435558/nonunion-of-fractures-of-the-ulna-and-radius-diaphyses-clinical-and-radiological-results-of-surgical-treatment
#12
H Boussakri, A Elibrahimi, M Bachiri, M Elidrissi, M Shimi, A Elmrini
Aseptic nonunion of the radius and ulna is a major complication of forearm fractures, accounting for 2% to 10% of all forearm fractures. The aim of our study is to evaluate the functional and radiological results of surgical treatment of diaphyseal aseptic nonunion of the radius and ulna, with autologous bone grafting, decortication and internal plate fixation. A series of 21 patients (26 nonunions) was retrospectively reviewed, the average age was 35 years with a mean of 31,58 years (range 12-44 years). The fractures included isolated radius (n=6) and ulna (n=10), and both radius and ulna (n=5)...
July 2016: Malaysian Orthopaedic Journal
https://www.readbyqxmd.com/read/28435449/zero-order-controlled-release-of-bmp2-derived-peptide-p24-from-the-chitosan-scaffold-by-chemical-grafting-modification-technique-for-promotion-of-osteogenesis-in-vitro-and-enhancement-of-bone-repair-in-vivo
#13
Yan Chen, Xujie Liu, Rui Liu, Yong Gong, Mingbo Wang, Qianli Huang, Qingling Feng, Bo Yu
Combination of tissue-engineered bone scaffolds with cell-adhesive, osteoconductive, or osteoinductive biomolecules is a critical strategy to improve their properties that significantly influence cellular behaviors, such as adhesion, proliferation, and differentiation, which is beneficial for critical-sized bone defects repairing. However, the traditional surface modification techniques, such as physical adsorption, coating, and plasma treatment, et al, have great limitations for immobilization of bioactive molecules due to undesirable controlled delivery performance or overly complex multistep procedures...
2017: Theranostics
https://www.readbyqxmd.com/read/28435060/the-multiple-therapeutic-applications-of-mirnas-for-bone-regenerative-medicine
#14
REVIEW
J C Scimeca, Elise Verron
With the aging of the general population, there is an increasing need for bone defect repair, prompting the development of reliable alternatives to autologous bone grafting, without the usually associated major drawbacks (i.e., limited volume and severe postoperative pain). Given the crucial role that miRNAs appear to have in bone tissue physiopathology, exploring their potential has recently garnered increased interest. In this review, we first describe the involvement of miRNAs in bone metabolism, and then focus on their potential therapeutic applications (as bone biomarkers and molecular targets)...
April 20, 2017: Drug Discovery Today
https://www.readbyqxmd.com/read/28434964/reconstruction-of-cranial-vault-defect-with-polyetheretherketone-peek-implants
#15
Pierre Brandicourt, Franck Delanoé, Franck-Emmanuel Roux, Florian Jalbert, David Brauge, Frédéric Lauwers
OBJECT: Reconstruction of a cranial vault defect is a frequent challenge in neurosurgery. Polyetheretherketone (PEEK) is used in many types of prostheses and has been employed for 10 years in our institution (University Hospital of Toulouse - France). The objectives of this study are to describe the benefits and drawbacks of reconstructing the cranial vault defect with a PEEK prosthesis. METHODS: Clinical data of the 37 patients who received a reconstruction with a custom-made PEEK prosthesis from 2007 to 2015 were retrospectively analysed...
April 18, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28434830/bone-formation-of-demineralized-human-dentin-block-graft-with-different-demineralization-time-in%C3%A2-vitro-and-in%C3%A2-vivo-study
#16
So-Min Park, David-Hyungjin Kim, Eun-Kyoung Pang
OBJECTIVE: To evaluate structural and physicochemical characteristics of demineralized human dentin block with increasing demineralization time and to assess new bone formation when onlay grafted at different demineralization times in rat calvaria. STUDY DESIGN: Extracted human permanent teeth were pretreated and demineralized for 10-90 min. Scanning electron microscopy, X-ray diffraction analysis, inductively coupled plasma spectrometry, and energy dispersive X-ray analysis were performed...
March 21, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28434577/50-years-ago-in-the-journal-of-pediatrics-thymic-dysplasia-swiss-agammaglobulinemia-i-graft-versus-host-reaction-following-bone-marrow-transfusion
#17
Emily Heikamp, Caridad Martinez
No abstract text is available yet for this article.
May 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28434011/management-of-coxa-vara-septica-and-pseudoarthrosis-of-the-femoral-neck-a-case-report
#18
Hasime Qorraj Bytyqi, Cen Bytyqi
BACKGROUND Coxa vara and pseudoarthrosis of the femoral neck after septic hip arthritis is a very rare disease. The aim of this study was to present a case with pseudoarthrosis of the femoral neck, with coxa vara after neonatal septic arthritis of the right hip, and treatment of the pseudarthrosis with proximal femoral valgus osteotomy. CASE REPORT A 12-month-old female, who had suffered neonatal septic arthritis with a five-day history of fever and painful right hip now demonstrated painless limping to the right hip, pelvic obliquity, Trendelenburg-Duchenne gait, limitation of hip abduction, lower-extremity length discrepancy with 3...
April 23, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28433848/instrumented-circumferential-fusion-in-two-stages-for-instable-lumbar-fracture-long-term-results-of-a-series-of-74-patients-on-sagittal-balance-and-functional-outcomes
#19
Mourad Ould-Slimane, Camille Damade, Guillaume Lonjon, André Gilibert, Jérôme Cochereau, Rémi Gauthé, Nicolas Lonjon
AIM: To report the radiological and functional results of a multicentre, prospective case series of patients with comminuted lumbar fractures treated with two-stage circumferential arthrodesis. METHODS: A multicentre, prospective case series of 74 patients with comminuted lumbar fractures was analyzed. The strategy entailed initial posterior osteosynthesis then physical replacement with an expandable titanium cage filled with autologous bone, via retroperitoneal lumbotomy...
April 19, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28433516/intravenous-mesenchymal-stromal-cell-therapy-for-inflammatory-bowel-disease-lessons-from-the-acute-graft-versus-host-disease-experience
#20
REVIEW
Laurie S Conklin, Patrick J Hanley, Jacques Galipeau, John Barrett, Cather M Bollard
Bone marrow-derived mesenchymal stromal cells (BMSCs) are primitive, supportive cells of the bone marrow with tri-lineage potential to differentiate into bone, cartilage, fat and muscle. These cells possess both in vitro and in vivo immunomodulatory and wound-healing properties. Several studies have demonstrated efficacy of intravenously administered BMSCs in treating acute graft-versus-host disease (GvHD). Use of intravenous (IV) BMSCs in inflammatory bowel diseases (IBD) in humans has been limited to small studies in adults, but results have been promising...
April 19, 2017: Cytotherapy
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