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https://www.readbyqxmd.com/read/27912150/calea-uniflora-less-attenuates-the-inflammatory-response-to-carrageenan-induced-pleurisy-in-mice
#1
Julia Salvan da Rosa, Silvana Virginia Gagliotti Vigil de Mello, Geison Vicente, Yeo Jim K Moon, Felipe Perozzo Daltoé, Tamires Cardoso Lima, Rafaela de Jesus Souza, Maique Weber Biavatti, Tânia Silvia Fröde
Calea uniflora Less. (family Asteraceae), also named "arnica" and "erva-de-lagarto", is a native plant to the South and Southeast of Brazil. This species was used to treat rheumatism, respiratory diseases, and digestive problems in Brazilian folk medicine. In vitro studies have shown the important biological effects of C. uniflora. However no studies have focused on the mechanism of action of anti-inflammatory activity of C. uniflora. The aim of this study was to evaluate the anti-inflammatory effects of the crude extract, its fractions, and isolated compounds obtained from of C...
November 29, 2016: International Immunopharmacology
https://www.readbyqxmd.com/read/27902616/diagnostic-accuracy-of-tumor-necrosis-factor-alpha-assay-for-tuberculous-pleurisy-a-prisma-compliant-meta-analysis
#2
Min Li, Zhuang Luo, Wenye Zhu, Rana Sami Ullah Khan, Saeed Ummai Ummair, Shaoqing Shi
BACKGROUND: The diagnosis of tuberculous pleurisy is difficult and traditional methods are not always helpful. Many studies have focused on the tumor necrosis factor-alpha (TNF-α) assay in pleural effusion for the diagnosis of tuberculous pleurisy, but the results remain controversial. This meta-analysis was conducted to determine the overall diagnostic accuracy of TNF-α. METHODS: Relevant studies were searched from PubMed, Embase, Web of Science, Chinese National Knowledge Infrastructure (CNKI), Wangfang, and Weipu...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27899783/-a-case-of-recurrent-breast-cancer-with-carcinomatous-pleurisy-successfully-treated-with-biweekly-paclitaxel-and-bevacizumab
#3
Takashi Yoshida, Yoshinari Goto, Kana Sakiyama, Morihiko Kimura
A 72-year-old woman underwent mastectomy with axillary lymph node dissection for left breast cancer at the age of 43 years, and was diagnosed with breast cancer metastasis to the pleura at the age of 68 years. She had been sequentially treated with hormonal therapies, but complained of a cough and dyspnea after 4 years. Chest radiography showed right pleural effusion, and cytological examination of the pleural effusion revealed adenocarcinoma cells. Biweekly paclitaxel and bevacizumab therapy was administered...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/27878909/role-of-mcp-1-in-pleural-effusion-development-in-a-carrageenan-induced-murine-model-of-pleurisy
#4
Sally M Lansley, Hui Min Cheah, Y C Gary Lee
BACKGROUND AND OBJECTIVE: Exudative pleural effusions affect over 1500 patients per million population each year. The pathobiology of pleural exudate formation remains unclear. Our recent study revealed monocyte chemotactic protein-1 (MCP-1) as a key driver of fibrinolytic-induced exudate effusion while another study found a role for MCP-1 in malignant effusion formation. In the present study, we further evaluated the role of MCP-1 in the development of pleural effusion in a mouse model of acute pleural inflammation...
November 22, 2016: Respirology: Official Journal of the Asian Pacific Society of Respirology
https://www.readbyqxmd.com/read/27796107/prevalence-of-lung-lesions-in-slaughtered-cattle-in-the-eastern-cape-province-south-africa
#5
Ishmael F Jaja, Borden Mushonga, Ezekiel Green, Voster Muchenje
Information obtained from abattoirs on the causes of lung condemnation is important in preventing the spread of zoonotic diseases and for promoting food security. In this study, we assessed the causes of lung condemnation in cattle at three abattoirs represented as ANA, QTA and EBA to evaluate the financial losses associated with lung condemnation. A retrospective study (n = 51 302) involving the use of abattoir slaughter records of 2010-2012 and an active abattoir survey (n = 1374) was conducted from July to December 2013...
October 26, 2016: Journal of the South African Veterinary Association
https://www.readbyqxmd.com/read/27773800/in-vitro-and-in-vivo-antimycobacterial-hepatoprotective-and-immunomodulatory-activity-of-euclea-natalensis-and-its-mode-of-action
#6
Namrita Lall, Vivek Kumar, Debra Meyer, Nomasomi Gasa, Chris Hamilton, Motlalepula Matsabisa, Carel Oosthuizen
ETHNOPHARMACOLOGICAL RELEVANCE: The Natal gwarri or Natal ebony (Euclea natalensis A.DC.) is a deciduous tree found widespread throughout southern Africa, especially in Kwazulu-Natal and the southern cost. It has been widely used by indigenous communities such as the Zulus, Tsongas and Vendas for symptoms related to tuberculosis (TB). The decoctions made from the plant parts are administered for chest diseases to treat complications such as chest pains, bronchitis, pleurisy and asthma...
October 20, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27765609/anti-inflammatory-effect-of-volatile-oil-from-schizonepeta-tenuifolia-on-carrageenin-induced-pleurisy-in-rats-and-its-application-to-study-of-appropriate-harvesting-time-coupled-with-multi-attribute-comprehensive-index-method
#7
Ming-Qiu Shan, Yan Qian, Sheng Yu, Shu-Chen Guo, Li Zhang, An-Wei Ding, Qi-Nan Wu
ETHNOPHARMACOLOGICAL RELEVANCE: Schizonepeta tenuifolia Briq. (ST) herbs have been used as a Traditional Chinese Medicine (TCM) for treating colds for thousands of years. The volatile oil is considered as the main material basis responsible for the efficacy of ST and has attracted lots of attention on its anti-inflammatory effect recently. AIM OF STUDY: This paper investigated the anti-inflammatory effects of the distilled volatile oils from Schizonepeta tenuifolia (STVO) that were collected at different harvesting times on carrageenin-induced pleurisy in rats...
October 17, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27765171/concomitant-interstitial-lung-disease-is%C3%A2-a%C3%A2-risk-factor-for-pleural-invasion-in-lung%C3%A2-cancer
#8
Atsushi Hata, Hidemi Suzuki, Takahiro Nakajima, Kazuhisa Tanaka, Taiki Fujiwara, Hironobu Wada, Takekazu Iwata, Shigetoshi Yoshida, Ichiro Yoshino
BACKGROUND: Lung carcinoma is often associated with interstitial lung disease (ILD), and the prognosis of lung cancer accompanied by ILD is unfavorable. In this study, cases of patients with primary lung cancer with or without ILD were reviewed to analyze surgical outcome, with special interest in the conformity of clinical and pathologic stages, pathologic findings of pleural invasion, malignant pleurisy first detected at the time of thoracotomy, and survival. METHODS: Retrospective chart review was performed for 1,264 primary lung cancer patients who underwent surgery from 2004 to 2015...
October 17, 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27759851/role-of-the-neutrophil-lymphocyte-ratio-in-the-differential-diagnosis-of-exudative-pleural-effusion
#9
Ulku Aka Akturk, Dilek Ernam, Makbule Ozlem Akbay, Nagihan Durmus Koçak, Erhan Ogur, Ilim Irmak
OBJECTIVES: Pleural effusion is a common diagnostic and clinical problem. The differential diagnosis of pleural effusion may be difficult and may require several procedures, including invasive ones. Certain studies have investigated biochemical parameters to facilitate the diagnosis of exudative pleural effusion; however, it remains a challenging problem in clinical practice. We aimed to investigate the potential role of the neutrophil-lymphocyte ratio, which can be easily obtained by determining the cell count of the pleural fluid, in the differential diagnosis of exudative pleural effusion...
October 1, 2016: Clinics
https://www.readbyqxmd.com/read/27696791/defining-low-disease-activity-in-systemic-lupus-erythematosus
#10
Ari Polachek, Dafna D Gladman, Jiandong Su, Murray B Urowitz
OBJECTIVES: To define and identify a group of SLE patients with low disease activity (LDA) and to examine whether it is similar to patients in remission and different from a high disease activity group (HDA) in short term outcomes. METHODS: LDA group was defined as Systemic Lupus Erythematosus Disease Activity Index (SLEDAI-2K) <3 including only 1 clinical manifestation of: rash, alopecia, mucosal ulcers, pleurisy, pericarditis, fever, thrombocytopenia or leukopenia...
October 1, 2016: Arthritis Care & Research
https://www.readbyqxmd.com/read/27684274/utility-of-macrophage-activated-marker-cd163-for-diagnosis-and-prognosis-in-pulmonary-tuberculosis
#11
Yuzo Suzuki, Masahiro Shirai, Kazuhiro Asada, Seiichi Miwa, Masato Karayama, Yutaro Nakamura, Naoki Inui, Toshihiro Shirai, Hiroshi Hayakawa, Satoshi Baba, Takafumi Suda
RATIONALE: Tuberculosis (TB) is a leading cause of death among infectious diseases worldwide. Accumulated knowledge has revealed that macrophages are deeply involved in the progression and pathogenesis of TB. We hypothesized that the evaluation of a macrophage activation marker may be useful in the diagnosis and assessment of pulmonary TB. OBJECTIVES: To examine the utility of the macrophage-activation marker sCD163 as a diagnostic tool and measure of disease severity for pulmonary TB and tuberculous pleurisy...
September 29, 2016: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/27666898/peripheral-neuropathy-in-systemic-lupus-erythematosus-clinical-and-electrophysiological-properties-and-their-association-with-disease-activity-parameters
#12
Renu Saigal, Rajat Bhargav, Laxmikant Goyal, Abhishek Agrawal, Pradeep Mital, Dileep Wadhwani
AIM: To study clinical and electrophysiological properties of peripheral neuropathy (PN) in systemic lupus erythematosus (SLE) and their association with disease activity parameters. METHODS: A hospital-based observational study done among 50 SLE patients after informed consent. History and clinical examination including a detailed neurological examination was carried out. Blood and urine investigation were done and modified SLE disease activity index (SLEDAI)-2000 score was calculated...
December 2015: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27665733/pd-1-t-cells-inhibit-effector-t-cells-at-the-pathologic-site-of-miliary-tuberculosis
#13
Amar Singh, Anant Mohan, Aprajit B Dey, Dipendra K Mitra
BACKGROUND: Optimal T cell activation is vital for the successful resolution of microbial infections. Programmed death-1 (PD-1) is key immune checkpoint receptor expressed by activated T cells. Aberrant/excessive inhibition mediated by PD-1 may impair host immunity to M. tuberculosis infection, leading to disseminated disease like miliary tuberculosis (MTB). PD-1 mediated inhibition of T cells in pulmonary tuberculosis and TB pleurisy is reported. However, their role in MTB, particularly at the pathologic sites remains to be addressed...
September 26, 2016: Clinical and Experimental Immunology
https://www.readbyqxmd.com/read/27642440/atypical-imaging-of-spinal-tuberculosis-a-case-report-and-review-of-literature
#14
Huijun Zhang, Zenghui Lu
This is a case report of spinal tuberculosis combined with sacroiliac joint tuberculosis, pulmonary tuberculosis, chest wall tuberculosis and tuberculous pleurisy and the image of the patient is rare, special and not typical and it looks like a halo sign. It has an important reference value for the diagnosis of spine tuberculosis although it is a rare imaging manifestation and diagnosis was confirmed by pathology after the surgery. Therefore atypical imaging is often appeared in clinical practice and it is meaningful and necessary for the diagnosis of atypical spinal tuberculosis combined with multiple organ tuberculosis...
2016: Pan African Medical Journal
https://www.readbyqxmd.com/read/27621864/characteristics-of-patients-with-pseudochylothorax-a-systematic-review
#15
Adriana Lama, Lucía Ferreiro, María E Toubes, Antonio Golpe, Francisco Gude, José M Álvarez-Dobaño, Francisco J González-Barcala, Esther San José, Nuria Rodríguez-Núñez, Carlos Rábade, Carlota Rodríguez-García, Luis Valdés
BACKGROUND: Pseudochylothorax (PCT) (cholesterol pleurisy or chyliform effusion) is a cholesterol-rich pleural effusion (PE) that is commonly associated with chronic inflammatory disorders. Nevertheless, the characteristics of patients with PCT are poorly defined. METHODS: A systematic review was performed across two electronic databases searching for studies reporting clinical findings, PE characteristics, and the most effective treatment of PCT. Case descriptions and retrospective studies were included...
August 2016: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/27612433/anti-inflammatory-antioxidant-and-anti-mycobacterium-tuberculosis-activity-of-viridiflorol-the-major-constituent-of-allophylus-edulis-a-st-hil-a-juss-cambess-radlk
#16
Lucas Noboru Fatori Trevizan, Kamilla Felipe do Nascimento, Joyce Alencar Santos, Candida Aparecida Leite Kassuya, Claudia Andrea Lima Cardoso, Maria do Carmo Vieira, Flora Martinez Figueira Moreira, Julio Croda, Anelise Samara Nazari Formagio
ETHNOPHARMACOLOGICAL RELEVANCE: The leaves of Allophylus edulis (A. St.-Hil., A. Juss. & Cambess.) Radlk. (Sapindaceae) are traditionally used as a natural anti-inflammatory agent; however, there are no scientific studies demonstrating its activity essential oil. The content of essential oil in A. edulis may be the chemical basis to explain its ethnobotanical uses, since infusions of this plant are used to treat inflammation in the traditional medicine in Brazil. AIM OF THE STUDY: This study evaluated the anti-inflammatory, antioxidant and anti-mycobacterial activities of the essential oil (EOAE) and viridiflorol, its main compound...
November 4, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27604674/intrapericardial-development-of-a-bronchogenic-cyst-case-report
#17
C Grozavu, A Fera, M Iliaş, D Pantile
INTRODUCTION: Bronchogenic cysts, commonly located in the mediastinum or lung parenchyma, arise from abnormal budding of the tracheobronchial tree. Since an unknown percentage of asymptomatic adult patients with bronchogenic cysts remain undiagnosed, the true natural history ofthese cysts in adults is uncertain and the available series reflect a significant selection bias in favor of the symptomatic individual. CASE REPORT: We present the case of a 42-year-old female who presented with adull central chest pain, which gradually worsened overseveral weeks...
July 2016: Chirurgia
https://www.readbyqxmd.com/read/27599565/malignant-mesothelioma-of-the-pleura-with-desmoplastic-histology-a-case-series-and-literature-review
#18
Kana Hashimoto, Yusuke Okuma, Yukio Hosomi, Tsunekazu Hishima
BACKGROUND: Desmoplastic malignant pleural mesothelioma (DMM) is rare histological subtype of diffuse malignant pleural mesothelioma (MPM), accounting for 5-10 % of cases. It has a poor prognosis, with direct invasion of the chest wall or lungs and distant metastases. Its pathological characteristics include dense collagen fibers in a storiform pattern. Its pretreatment pathological diagnosis is difficult, with fibrous pleuritis and reactive mesothelial hyperplasia as potential differential diagnoses...
2016: BMC Cancer
https://www.readbyqxmd.com/read/27590355/design-synthesis-and-pharmacological-evaluation-of-new-anti-inflammatory-compounds
#19
Amanda F Cidade, Patrícia A Vasconcelos, Daiany P B Silva, Iziara F Florentino, Géssica A Vasconcelos, Boniek G Vaz, Elson A Costa, Luciano M Lião, Ricardo Menegatti
Inflammatory diseases and pain are among the main problems that significantly influence the lifestyle of millions of people and existing therapies are not always effective and can cause several adverse effects. In this context, the molecular modifications or synthesis of compounds continue being the best strategies for the identification of new compounds for the treatment of pain and inflammation. The aim of this study was to evaluate the analgesic and anti-inflammatory activities of new analogues of pyrazole compounds containing subunits N-phenyl-1-H-pirazoles and 1,3,4-oxadiazole-2(3H)-thione, LQFM-146, LQFM-147 and LQFM-148...
August 30, 2016: European Journal of Pharmacology
https://www.readbyqxmd.com/read/27537907/tpgs-stabilized-curcumin-nanoparticles-exhibit-superior-effect-on-carrageenan-induced-inflammation-in-wistar-rat
#20
Heni Rachmawati, Dewi Safitri, Aditya Trias Pradana, I Ketut Adnyana
Curcumin, a hydrophobic polyphenol compound derived from the rhizome of the Curcuma genus, has a wide spectrum of biological and pharmacological applications. Previously, curcumin nanoparticles with different stabilizers had been produced successfully in order to enhance solubility and per oral absorption. In the present study, we tested the anti-inflammatory effect of d-α-Tocopheryl polyethylene glycol 1000 succinate (TPGS)-stabilized curcumin nanoparticles in vivo. Lambda-carrageenan (λ-carrageenan) was used to induce inflammation in rats; it was given by an intraplantar route and intrapelurally through surgery in the pleurisy test...
August 16, 2016: Pharmaceutics
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