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https://www.readbyqxmd.com/read/28317818/erratum-evaluation-of-different-laboratory-methods-for-rapid-diagnosis-of-tuberculous-pleurisy
#1
(no author information available yet)
[This corrects the article DOI: 10.1016/j.ijmyco.2016.07.001.].
January 2017: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/28304239/immunoglobulin-g4-related-epidural-inflammatory-pseudotumor-presenting-with-pulmonary-complications-and-spinal-cord-compression-case-report
#2
Kavelin Rumalla, Kyle A Smith, Paul M Arnold
Immunoglobulin G4-related disease (IgG4-RD) is a recently defined condition characterized by inflammatory tumefactive lesions in various organ systems. IgG4-RD is a clinical and radiological diagnosis of exclusion and requires the presence of specific histopathological criteria for diagnosis. A 50-year-old man presented to an outside hospital with a 3-month history of progressively worsening back pain and symptoms of pleurisy, nasal crusting, and hematochezia. Radiological workup revealed an epidural-paraspinal mass with displacement of the spinal cord, destruction of the T5-6 vertebrae, and extension into the right lung...
March 17, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28290161/corticosteroids-for-tuberculous-pleurisy
#3
REVIEW
Hannah Ryan, Jinho Yoo, Padmapriya Darsini
BACKGROUND: Corticosteroids used in addition to antituberculous therapy have been reported to benefit people with tuberculous pleurisy. However, research findings are inconsistent and raise doubt as to whether such treatment is worthwhile. There is also concern regarding the potential adverse effects of corticosteroids, especially in HIV-positive people. OBJECTIVES: To evaluate the effects of adding corticosteroids to drug regimens for tuberculous pleural effusion...
March 14, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28284315/long-term-outcome-of-patients-with-nonspecific-pleurisy-at-medical-thoracoscopy
#4
Yuan Yang, Yan-Bing Wu, Zhen Wang, Xiao-Juan Wang, Li-Li Xu, Zhao-Hui Tong, Huan-Zhong Shi
BACKGROUND: Medical thoracoscopy is an effective and safe procedure for diagnosing pleural effusions of undetermined causes. But there are still a part of patients with pleural effusions were diagnosed as nonspecific pleurisy when no specific biopsy results were found after undergoing thoracoscopic biopsy. The long-term outcome of these patients is unclear, and anxieties about undiagnosed malignancy persist. METHODS: Between July 2005 and June 2014, medical thoracoscopy using the semi-rigid instrument was performed and pleural biopsy was taken in 833 patients with pleural effusions...
March 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28282613/design-synthesis-and-evaluation-of-novel-feruloyl-donepezil-hybrids-as-potential-multitarget-drugs-for-the-treatment-of-alzheimer-s-disease
#5
Kris Simone T Dias, Cynthia T de Paula, Thiago Dos Santos, Isis N O Souza, Marina S Boni, Marcos J R Guimarães, Fernanda M R da Silva, Newton G Castro, Gilda A Neves, Clarice C Veloso, Márcio M Coelho, Ivo Souza F de Melo, Fabiana C V Giusti, Alexandre Giusti-Paiva, Marcelo L da Silva, Laurent E Dardenne, Isabella A Guedes, Letizia Pruccoli, Fabiana Morroni, Andrea Tarozzi, Claudio Viegas
A novel series of feruloyl-donepezil hybrid compounds were designed, synthesized and evaluated as multitarget drug candidates for the treatment of Alzheimer's Disease (AD). In vitro results revealed potent acetylcholinesterase (AChE) inhibitory activity for some of these compounds and all of them showed moderate antioxidant properties. Compounds 12a, 12b and 12c were the most potent AChE inhibitors, highlighting 12a with IC50 = 0.46 μM. In addition, these three most promising compounds exhibited significant in vivo anti-inflammatory activity in the mice paw edema, pleurisy and formalin-induced hyperalgesy models, in vitro metal chelator activity for Cu(2+) and Fe(2+), and neuroprotection of human neuronal cells against oxidative damage...
April 21, 2017: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/28275073/rapid-detection-of-cell-free-mycobacterium-tuberculosis-dna-in-tuberculous-pleural-effusion
#6
Nanying Che, Xinting Yang, Zichen Liu, Kun Li, Xiaoyou Chen
Tuberculous pleurisy is one of the most common extra-pulmonary tuberculosis, but its diagnosis remains to be difficult. In this study, we for the first time report detection of cell-free Mycobacterium tuberculosis DNA in pleural effusion and evaluation of this newly developed molecular assay. A total of 78 patients with pleural effusion, 60 patients with tuberculous pleurisy and 18 patients with alternative diseases, were included in this study. Mycobacterial culture, Xpert MTB/RIF assay, adenosine deaminase assay, T-SPOT...
March 8, 2017: Journal of Clinical Microbiology
https://www.readbyqxmd.com/read/28242648/identification-of-novel-chondroprotective-mediators-in-resolving-inflammatory-exudates
#7
Magdalena K Kaneva, Karin V Greco, Sarah E Headland, Trinidad Montero-Melendez, Prashant Mori, Kevin Greenslade, Costantino Pitzalis, Adrian Moore, Mauro Perretti
We hypothesized that exudates collected at the beginning of the resolution phase of inflammation might be enriched for tissue protective molecules; thus an integrated cellular and molecular approach was applied to identify novel chondroprotective bioactions. Exudates were collected 6 h (inflammatory) and 24 h (resolving) following carrageenan-induced pleurisy in rats. The resolving exudate was subjected to gel filtration chromatography followed by proteomics, identifying 61 proteins. Fractions were added to C28/I2 chondrocytes, grown in micromasses, ions with or without IL-1β or osteoarthritic synovial fluids for 48 h...
February 27, 2017: Journal of Immunology: Official Journal of the American Association of Immunologists
https://www.readbyqxmd.com/read/28222179/seed-and-peel-essential-oils-obtained-from-campomanesia-adamantium-fruit-inhibit-inflammatory-and-pain-parameters-in-rodents
#8
Danieli Zuntini Viscardi, Jucicléia da Silva Arrigo, Camila de Azevedo Chaves Correia, Cândida Aparecida Leite Kassuya, Claudia Andrea Lima Cardoso, Iriani Rodrigues Maldonade, Eliana Janet Sanjinez Argandoña
Campomanesia adamantium (Myrtaceae) is popularly known as "gabiroba" and has been used in folk medicine as antirheumatic, antidiarrheal, hypocholesterolemic and anti-inflammatory. This study evaluated the anti-inflammatory and antinociceptive activities and toxicology of essential oils from peel (EOP) and seed (EOS) of C. adamantium fruits in animal models. Different groups were treated with doses of 100 and 300 mg/kg and the inflammatory parameters were evaluated in carrageenan induced paw oedema and leukocyte migration in pleurisy model, while antinociceptive activity was evaluated using formalin method in rodents...
2017: PloS One
https://www.readbyqxmd.com/read/28214065/-contribution-of-the-xpert-mtb-rif-to-the-etiological-diagnosis-of-tuberculous-pleurisy
#9
N O Touré, M Wayzani, K Thiam, M F Cissé, F B Mbaye
INTRODUCTION: Performance of the Xpert MTB/RIF for the detection of Mycobacterium tuberculosis in pleural liquid is poorly described. The aim of this study was to determine its usefulness for the etiological diagnosis of a tuberculous pleurisy. PATIENTS AND METHOD: We performed a descriptive cross-sectional study, with analytical design, including all the patients having a unilateral serofibrinous pleurisy, exudative, lymphocytic, and sterile. The diagnosis of pleural tuberculosis was considered based on epidemiological, clinical, paraclinical and therapeutic arguments...
February 14, 2017: Revue des Maladies Respiratoires
https://www.readbyqxmd.com/read/28190533/the-roles-of-a-ribosomal-protein-s19-polymer-in-a-mouse-model-of-carrageenan-induced-acute-pleurisy
#10
Koji Yamanegi, Toru Kawakami, Naoko Yamada, Shunsuke Kumanishi, Hiroyuki Futani, Keiji Nakasho, Hiroshi Nishiura
C5-deficient mice usually present moderate neutrophil activation during the initiation phase of acute inflammation. Conversely, C5a receptor (C5aR)-deficient mice show unusually excessive activation of neutrophils. We identified the ribosomal protein S19 (RP S19) polymer, which is cross-linked at Lys122 and Gln137 by transglutaminases in apoptotic neutrophils, as a second C5aR ligand during the resolution phase of acute inflammation. The RP S19 polymer promotes apoptosis via the neutrophil C5aR and phagocytosis via the macrophage C5aR...
February 7, 2017: Immunobiology
https://www.readbyqxmd.com/read/28185999/ct-findings-of-pulmonary-tuberculosis-and-tuberculous-pleurisy-in-diabetes-mellitus-patients
#11
Jihyun Kim, In Jae Lee, Joo Hee Kim
PURPOSE: We aimed to assess computed tomography (CT) findings of pulmonary tuberculosis (TB) and TB pleurisy in diabetes mellitus (DM) patients and to evaluate the effect of duration of DM on radiologic findings of pulmonary TB and TB pleurisy. METHODS: Ninety-three consecutive patients diagnosed as active pulmonary TB with underlying DM were enrolled in our study. As a control group, 100 pulmonary TB patients without DM were randomly selected. TB patients with DM were subdivided into two subgroups depending on diabetes duration of ≥10 years or <10 years...
March 2017: Diagnostic and Interventional Radiology: Official Journal of the Turkish Society of Radiology
https://www.readbyqxmd.com/read/28178706/coexistent-sarcoidosis-and-tuberculosis-a-case-report
#12
Cristiano Carbonelli, Ernesto Giuffreda, Antonio Palmiotti, Domenico Loizzi, Filippo Lococo, Elisiana Carpagnano, Donato Lacedonia, Francesco Sollitto, Maria Pia Foschino
Necrotizing granulomatous diseases of the lungs are usually dependent on a narrow range of differential diagnoses. Tuberculosis (TB) is responsible for the largest number of cases, while necrotizing sarcoidosis is generally considered a rare and easily distinguishable disease substantially based on histological features. However, this entity has become a viable diagnosis in the absence of mycobacteria isolation or when a remarkable clinical improvement cannot be achieved with the combination of anti-TB drugs at full dosage...
February 9, 2017: Respiration; International Review of Thoracic Diseases
https://www.readbyqxmd.com/read/28133268/-long-term-survival-after-reoperation-for-lung-metastasis-of-resected-pancreatic-adenocarcinoma-a-case-report
#13
Hirosuke Ishikawa, Kabuto Takano, Takuya Ando, Daiki Soma, Kizuki Yuza, Yuki Hirose, Tomohiro Katada, Kohei Miura, Taku Ohashi, Kazuyasu Takizawa, Masayuki Nagahashi, Jun Sakata, Hitoshi Kameyama, Takashi Kobayashi, Toshifumi Wakai
A 66-year-old woman with pancreatic cancer underwent resection of the pancreatic body and tail. Thirty-seven months after the initial surgery, a tumor was found in S4 of the right lung, for which resection of the middle lobe of the lung was performed. A diagnosis of lung metastasis originating from pancreatic cancer was confirmed based on histological and immunohistopathological assessments. Sixty-seven months after the initial surgery, despite the gemcitabine-based adjuvant chemotherapy, a tumor was detected in S3 of the left lung, for which partial lung resection was performed...
November 2016: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28121949/reactive-oxygen-species-modulator-1-romo1-as-a-novel-diagnostic-marker-for-lung-cancer-related-malignant-effusion
#14
Seung Hyeun Lee, Myung Jae Park, Sue In Choi, Eun Joo Lee, Sang Yeub Lee, Kwang Ho In
Reactive oxygen species modulator 1 (Romo1) is a novel protein that plays an important role in intracellular reactive oxygen species generation. Recently, Romo1 has been suggested to have diagnostic and prognostic potential in lung cancer. However, there is no data on the diagnostic value of Romo1 level in malignant pleural effusion. We evaluated the clinical usefulness of Romo1 in pleural fluid for the diagnosis of malignant effusion in lung cancer patients. Pleural fluid Romo1 level was measured using enzyme-linked immunosorbent assay and compared between lung cancer-associated malignant effusion (n = 53; 29 adenocarcinomas and 24 squamous cell carcinomas) and benign pleural effusions (n = 91; 31 tuberculous pleurisy, 30 parapneumonic effusion, and 30 transudate)...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28119752/progression-of-tuberculous-pleurisy-from-a-lymphocyte-predominant-free-flowing-effusion-to-a-neutrophil-predominant-loculated-effusion
#15
EDITORIAL
Won-Jung Koh
No abstract text is available yet for this article.
January 2017: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/28109914/anti-inflammatory-and-toxicological-evaluation-of-essential-oil-from-piper-glabratum-leaves
#16
Lidiane Schultz Branquinho, Joyce Alencar Santos, Claudia Andrea Lima Cardoso, Jonas da Silva Mota, Ubirajara Lanza Junior, Cândida Aparecida Leite Kassuya, Arielle Cristina Arena
ETHNOPHARMACOLOGICAL RELEVANCE: Although some of the species of the genus Piper exhibit interesting biological properties, studies on Piper glabratum Kunth are very limited. AIM OF THE STUDY: This study investigated the anti-inflammatory activity and the toxicological profile of the essential oil from P. glabratum leaves (OEPG) in mice. MATERIALS AND METHODS: The acute toxicity of OEPG was evaluated by oral administration to female mice as single doses of 500, 1000, 2000 or 5000mg/kg/body weight...
January 18, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28057604/biological-markers-in-the-diagnosis-of-tuberculous-pleural-effusion
#17
REVIEW
Bastien Mollo, Stéphane Jouveshomme, François Philippart, Benoît Pilmis
Tuberculosis is one of the main etiologies to evoke in the context of lymphocyte pleurisy. However, diagnosis is difficult and is based on mycobacteriology that is not enough sensitive and time-consuming, or on histology that requires invasive biopsy gesture. This literature review, carried out from Medline, summarizes the main meta-analyzes, reviews, and originator publications in English on biomarkers, classic and more innovative, studied for the diagnosis of tuberculous pleurisy. Among the immuno-biochemical markers, interferon-γ (IFN-γ), isoenzyme of adenosine deaminase 2 (ADA2) and total adenosine deaminase (ADA) seem the most relevant with respective sensitivities of 89% (87-91), 97...
February 1, 2017: Annales de Biologie Clinique
https://www.readbyqxmd.com/read/27986981/-pulmonary-causes-of-chest-pain
#18
B Jany
Chest pain represents one of the most frequent symptoms of pulmonary diseases, in addition to dyspnea and cough. The broad differential diagnostics include the intensely painful but prognostically benign acute pleurisy as well as potentially life-threatening events, such as acute pulmonary embolism or malignant chest diseases. Primary spontaneous pneumothorax is characterized by acute chest pain. Pain associated with a respiratory infection, such as pneumonia rarely poses a difficult diagnostic problem. Painful diseases of the lungs can be differentiated in an initial approach by asking the patient if the pain is related to breathing, which is characteristic of pleuritic chest diseases...
January 2017: Der Internist
https://www.readbyqxmd.com/read/27976470/esi-ms-2-and-anti-inflammatory-studies-of-cyclopropanic-triterpenes-uplc-esi-ms-and-ms-2-search-of-related-metabolites-from-donella-ubanguiensis
#19
Louis P Sandjo, Marcus V P Dos Santos Nascimento, Layzon A L da Silva, Antonio C M Munhoz, Luiz A E Pollo, Maique W Biavatti, Bonaventure T Ngadjui, Till Opatz, Tania S Fröde
INTRODUCTION: Triterpenes are one of the largest secondary metabolites groups spread in the plant kingdom with various skeletons. These metabolites have showed various bioactivities including anti-inflammatory activity. OBJECTIVE: The study aims to explore the mass spectrometry fragmentation of donellanic acids A-C (DA A-C), three compounds identified from Donella ubanguiensis; in addition, the fragmentation behaviour of these metabolites will serve as a fingerprint to search and characterise triterpenes congeners in fruits, bark and wood crude extracts of D...
January 2017: Phytochemical Analysis: PCA
https://www.readbyqxmd.com/read/27931685/evaluation-of-different-laboratory-methods-for-rapid-diagnosis-of-tuberculous-pleurisy
#20
Safaa Amer, Azza El Hefnawy, Nashwa Abdel Wahab, Hadir Okasha, Amira Baz
BACKGROUND/OBJECTIVE: Tuberculous pleurisy is a diagnostic challenge due to its nonspecific clinical presentation, paucibacillary nature of the effusion together with the inefficiency of conventional laboratory methods motivating the evaluation of variable diagnostic strategies. METHODS: Using thoracoscopy, the pleural cavity of 50 patients with undiagnosed exudative pleural effusion were fully examined and biopsy specimens of affected parietal pleura were taken under direct vision...
December 2016: International Journal of Mycobacteriology
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