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Obstructive salivary gland disease

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https://www.readbyqxmd.com/read/28177330/outcomes-of-interventional-sialendoscopy-for-obstructive-salivary-gland-disorders-an-italian-multicentre-study
#1
A Gallo, P Capaccio, M Benazzo, L De Campora, M De Vincentiis, P Farneti, M Fusconi, M Gaffuri, F Lo Russo, S Martellucci, F Ottaviani, G Pagliuca, G Paludetti, E Pasquini, L Pignataro, R Puxeddu, M Rigante, E Scarano, S Sionis, R Speciale, P Canzi
Interventional sialendoscopy has become the predominant therapeutic procedure for the management of obstructive salivary disorders, but only a few multicentre studies of large series of patients with a long-term follow-up have been published. This Italian multicentre study involved 1152 patients (553 females; mean age 50 years) who, after at least a clinical and ultrasonographic evaluation, underwent a total of 1342 diagnostic and interventional sialendoscopies, 44.6% of which involved the parotid gland. 12% (n = 138) of patients underwent multiple treatments...
December 2016: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/28091932/current-concept-of-igg4-related-disease
#2
Kazuichi Okazaki, Hisanori Umehara
IgG4-related disease (IgG4-RD) is a fibroinflammatory disease of unknown etiology, which is characterized by a tendency to form tumefactive lesions, increased serum levels of IgG4, and massive infiltration of IgG4-positive plasma cells with storiform fibrosis and/or obliterative phlebitis. Patients with IgG4-RD have frequently multiorgan involvements such as the pancreas, biliary tree, salivary glands, periorbital tissues, kidneys, lungs, lymph nodes, and retroperitoneum. IgG4-RD mainly affects middle-aged to elderly men except for involvement in lachrymal and salivary glands, so-called Mikulicz's disease...
December 28, 2016: Current Topics in Microbiology and Immunology
https://www.readbyqxmd.com/read/27987516/-non-hodgkin-s-lymphoma-mimicking-mikulicz-disease-a-case-report
#3
A C Liu, Y Chen, J S Jia, S Y Gao, Y Y Liu
IgG4-related disease is a systemic disorder involving a spectrum of multiple indications, and various histopathological features are shared among different IgG4-related disease subtypes, which challenge diagnosis, although certain syndromes have organ-specific involvement. Among them, Mikulicz's disease affecting the salivary and lacrimal glands, distinguished by often elevated levels of serum IgG4, infiltration of IgG4(+) plasma cells into target tissues, and diffuse swelling, mass formation, or fibrosis of affected organs...
December 18, 2016: Beijing da Xue Xue Bao. Yi Xue Ban, Journal of Peking University. Health Sciences
https://www.readbyqxmd.com/read/27866757/differential-diagnosis-of-igg4-related-sialadenitis-primary-sj%C3%A3-gren-syndrome-and-chronic-obstructive-submandibular-sialadenitis
#4
X Hong, W Li, X-Y Xie, Z-Y Zhang, Y Chen, Y Gao, X Peng, J-Z Su, Y-Y Zhang, Z Wang, Z-G Cai, L Zhang, Y-Y Liu, J He, L-M Ren, Z-G Li, G-Y Yu
Our aim was to differentiate IgG4-related sialadenitis, primary Sjögren syndrome, and chronic obstructive submandibular sialadenitis by analysing clinical, radiographic, and pathological features. Fifty-five patients, 50, and 50 were enrolled, respectively and their baseline characteristics and serological, sialographic, and pathological findings compared. The male:female ratio for IgG4-related sialadenitis was 1:1.2 for primary Sjögren syndrome 1:15.7, and for chronic obstructive submandibular sialadenitis1:0...
February 2017: British Journal of Oral & Maxillofacial Surgery
https://www.readbyqxmd.com/read/27790453/primary-salivary-gland-malignancy-of-trachea-a-clinical-masquerader
#5
Monika Singh, Megha Sharma, Minakshi Bhardwaj, Prajwala Gupta, Arvind Ahuja
Primary tracheal malignancies are rare and present with non specific symptoms hence delaying the diagnosis. A 41-year-old male presented with repeated paroxysmal episodes of breathlessness for which he was being treated with bronchodilators and steroids. Computed Tomography (CT) chest was done revealing a small polypoidal mass lesion arising from lower trachea/carina. On fibre optic bronchoscopy an infiltrative growth was seen at the lower end of trachea following which biopsy was obtained. On histopathologic examination a diagnosis of primary adenoid cystic carcinoma was made...
September 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27764856/-surgery-in-salivary-gland-diseases
#6
K Möller, N Kohles, D Eßer
Salivary gland surgery is a common procedure in otorhinolaryngology. Parotidectomy and submandibulectomy represent the treatment of choice in benign and malignant tumors of the salivary glands. However, as to this point there are no guidelines are concerning diagnostic and therapeutic approaches of benign and malignant tumors of the salivary gland. Since the introduction of sialendoscopy there are new diagnostic and therapeutic procedures available in treating obstructive sialadenitis. The present article provides an overview of anatomical principles, diagnostic approaches and the most important salivary gland surgeries for future otorhinolaryngologists under specialist training...
October 2016: Laryngo- Rhino- Otologie
https://www.readbyqxmd.com/read/27714410/role-of-cftr-in-epithelial-physiology
#7
REVIEW
Vinciane Saint-Criq, Michael A Gray
Salt and fluid absorption and secretion are two processes that are fundamental to epithelial function and whole body fluid homeostasis, and as such are tightly regulated in epithelial tissues. The CFTR anion channel plays a major role in regulating both secretion and absorption in a diverse range of epithelial tissues, including the airways, the GI and reproductive tracts, sweat and salivary glands. It is not surprising then that defects in CFTR function are linked to disease, including life-threatening secretory diarrhoeas, such as cholera, as well as the inherited disease, cystic fibrosis (CF), one of the most common life-limiting genetic diseases in Caucasian populations...
January 2017: Cellular and Molecular Life Sciences: CMLS
https://www.readbyqxmd.com/read/27701754/sialadenitis-without-sialolithiasis-prospective-outcomes-after-sialendoscopy-assisted-salivary-duct-surgery
#8
Elise A Delagnes, Annick Aubin-Pouliot, Melissa Zheng, Jolie L Chang, William R Ryan
OBJECTIVES: To prospectively assess symptoms before and after sialendoscopy-assisted salivary duct surgery (SASDS) in patients with symptomatic sialadenitis without sialolithiasis. STUDY DESIGN: Prospective cohort study. METHODS: Patients with chronic obstructive sialadenitis without sialolithiasis (COSWS) completed the Chronic Obstructive Sialadenitis Symptoms (COSS) questionnaire prior to SASDS and 3 months postoperatively. RESULTS: Of 80 consecutive patients in a 20-month period, 20 surveyed patients underwent SASDS for COSWS in 37 symptomatic glands...
October 4, 2016: Laryngoscope
https://www.readbyqxmd.com/read/27320298/case-of-suspected-sialodochitis-fibrinosa-kussmaul-s-disease
#9
Kamichika Hayashi, Takeshi Onda, Hitoshi Ohata, Nobuo Takano, Takahiko Shibahara
Here we report a case of Kussmaul's disease, or sialodochitis fibrinosa. This rare disease is characterized by recurrent swelling of the salivary glands, which then discharge clots of fibrin into the oral cavity. An 80-year-old man with a history of allergic rhinitis visited our department with the chief complaint of pain in the bilateral parotid gland area on eating. An initial examination revealed mild swelling and tenderness in this region, and indurations could be felt around the bilateral parotid papillae...
2016: Bulletin of Tokyo Dental College
https://www.readbyqxmd.com/read/27240495/mucocele-of-the-hard-palate-in-children
#10
Mosaad Abdel-Aziz, Badawy Khalifa, Ahmed Nassar, Ahmed Kamel, Nader Naguib, Abdel-Rahman El-Tahan
OBJECTIVE: Mucus retention cyst of the hard palate may result from obstruction of the ducts of the minor salivary glands, and it was defined as a mucocele. Although, the disease is not common in the hard palate, it was previously reported by many authors in the soft palate. The aim of our study was to present pediatric patients who were diagnosed to have mucocele of the hard palate, and to evaluate the outcome of the surgical excision of this lesion. METHODS: This is a case series study included 8 pediatric patients who presented with cystic lesions on the hard palate which were removed surgically, and were diagnosed as mucoceles...
June 2016: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/27185233/sialendoscopy-and-sialendoscopically-assisted-operations-in-the-treatment-of-lithiasis-of-the-submandibular-and-parotid-glands-our-experience-of-239-cases
#11
Tomasz Kopeć, Małgorzata Wierzbicka, Jarosław Kałużny, Anna Młodkowska, Witold Szyfter
We present the results of treatment of sialolithiasis of the submandibular and parotid glands using sialendoscopy and sialendoscopy-assisted surgery. Between 2009-2013, 397 consecutive patients (mean (range) age 48 (18-76) years) were treated for obstructive diseases of the major salivary glands (sialolithiasis n=239, 175 submandibular and 64 parotid). In a total of 175 patients with 191 stones in the submandibular gland treated by endoscopic retrieval or surgical release, 149 patients (85%) were rendered free of stones (by sialendoscopy alone n=82, and sialendoscopy with operation n=67) Twenty patients (11%) had residual stones and 6 patients (4%) required excisionof the gland...
September 2016: British Journal of Oral & Maxillofacial Surgery
https://www.readbyqxmd.com/read/27160691/-swelling-of-the-submandibular-and-parotid-glands-a%C3%A2-description-of-possible-differential-diagnoses
#12
B Hofauer, A Chaker, T Strenger, M Bas, N Mansour, A Knopf
Swelling of single or multiple major salivary glands can be caused by various local or systemic diseases. In differential diagnosis, congenital cystic or vascular malformations should be considered, as well as infectious or tumorous alterations. Salivary duct obstructions due to sialolithiasis or stenosis can cause salivary gland enlargement. Multiple systemic diseases can have manifestations in the parotid or submandibular glands. As therapy varies from cause to cause, knowledge of the different potential diagnoses is crucial...
May 2016: HNO
https://www.readbyqxmd.com/read/27092950/surgery-for-malignant-sublingual-and-minor-salivary-gland-neoplasms
#13
REVIEW
Patrick J Bradley, Robert L Ferris
Malignant sublingual gland neoplasms are rare, early-stage neoplasms presenting as painless non-ulcerated masses in the antero-lateral floor of the mouth. The majority of patients present with advanced disease, with symptoms of pain or anaesthesia of the tongue. Malignant minor salivary gland neoplasms are more common, the majority (>80%) of which present in the oral cavity, most frequently in the palatal area, as painless masses or as obstructive symptoms in the head and neck region. The most frequent pathologies are adenoid cystic carcinoma and mucoepidermoid carcinoma (>85%), with the majority presenting at an advanced stage (III/IV)...
2016: Advances in Oto-rhino-laryngology
https://www.readbyqxmd.com/read/26972293/sialendoscopy-assisted-surgery-and-the-chronic-obstructive-sialadenitis-symptoms-questionnaire-a-prospective-study
#14
Annick Aubin-Pouliot, Elise A Delagnes, Jolie L Chang, William R Ryan
OBJECTIVES/HYPOTHESIS: To prospectively assess symptoms of obstructive sialadenitis before and after sialendoscopy-assisted salivary duct surgery (SASDS) using the chronic obstructive sialadenitis symptoms (COSS) questionnaire to determine and predict impact of interventions. STUDY DESIGN: Prospective cohort study. METHODS: Adult patients with chronic obstructive sialadenitis who underwent SASDS were asked to complete the COSS questionnaire and the Short-Form-8 (SF-8) quality-of-life (QOL) survey prior to surgery and 3 months postoperatively...
June 2016: Laryngoscope
https://www.readbyqxmd.com/read/26889264/recurrent-sialoliths-after-excision-of-the-bilateral-submandibular-glands-for-sialolithiasis-treatment-a-case-report
#15
Xiaoxia Ying, Jianan Kang, Fuyin Zhang, Hui Dong
Sialolithiasis is a common disease that is characterized by the obstruction of the salivary gland. Sialolithiasis mainly affects the submandibular glands and the Wharton's duct. However, bilateral sialolithiasis is a rare condition. In addition, recurrence of sialoliths subsequent to surgical excision of the submandibular gland for the treatment of sialolithiasis has been rarely reported. The present study reported a case presenting with recurrent sialoliths with sialadenitis in the residual Wharton's duct following the excision of bilateral submandibular glands...
January 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/26847635/surgical-treatment-of-mucoepidermoid-carcinoma-of-the-lung-20-years-experience
#16
Takayoshi Yamamoto, Takahiro Nakajima, Hidemi Suzuki, Tetsuzo Tagawa, Takekazu Iwata, Teruaki Mizobuchi, Shigetoshi Yoshida, Yukio Nakatani, Ichiro Yoshino
BACKGROUND: Pulmonary mucoepidermoid carcinoma is a rare salivary gland-type neoplasm. We aimed to elucidate the optimal management of this rare condition by reviewing the treatment outcomes of patients at our institution with mucoepidermoid carcinoma of the lung. METHODS: We performed a retrospective review of all patients with pulmonary mucoepidermoid carcinoma who underwent surgical treatment between January 1993 and December 2012. We reviewed the patients' clinical characteristics and the therapeutic interventions undertaken...
March 2016: Asian Cardiovascular & Thoracic Annals
https://www.readbyqxmd.com/read/26824914/learning-curve-in-diagnostic-and-interventional-sialendoscopy-for-obstructive-salivary-diseases
#17
REVIEW
P Farneti, G Macrì, G Gramellini, M Ghirelli, F Tesei, E Pasquini
Sialendoscopy is a new diagnostic and surgical tool for management of salivary gland diseases that offers the opportunity to treat selected pathologies less invasively and with better results compared to previous techniques. As with any new technique, an adequate training programme involving a gradual learning curve is mandatory to quickly obtain results similar to those reported in the literature. This includes an appropriate diagnostic programme, correct patient selection and knowledge of possible pitfalls...
October 2015: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/26805187/-pulmonary-mucoepidermoid-carcinoma-a-case-report
#18
Hideoki Yokouchi, Masaki Miyazaki, Takeaki Miyamoto, Takafumi Minami, Fumio Tsuji, Kohei Murata, Kazuhito Ohishi
Mucoepidermoid carcinoma (MEC) of the lungs is a rare type of lung cancer, mainly arising from the submucosal salivary type mucous glands of the large bronchi. MEC is classified into low- and high-grade subtypes based on its cytological and histological features, and this classification correlates well with prognosis. We report the case of a 36-year-old man diagnosed after an initial episode of obstructive pneumonia. CT and bronchoscopy revealed an endobronchial mass in the right S3 bronchus and distal atelectasis...
November 2015: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/26788478/deep-neck-space-infections-a-study-of-76-cases
#19
Gaurav Kataria, Aditi Saxena, Sanjeev Bhagat, Baldev Singh, Manpreet Kaur, Gurpreet Kaur
INTRODUCTION: Deep neck space infections (DNSI) are serious diseases that involve several spaces in the neck. The common primary sources of DNSI are dental infections, tonsillar and salivary gland infections, malignancies, and foreign bodies. With widespread use of antibiotics, the prevalence of DNSI has been reduced. Common complications of DNSI include airway obstruction, jugular vein thrombosis, and sepsis. Treatment principally comprises airway management, antibiotic therapy, and surgical intervention...
July 2015: Iranian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/26604966/giant-sialoliths-of-wharton-duct-report-of-two-rare-cases-and-review-of-literature
#20
Hossein Shahoon, Sareh Farhadi, Roya Hamedi
Sialolithiasis is a common disease of the major salivary glands, characterized by the obstruction of a salivary gland or its excretory duct due to the formation of calcareous concretions. Sialoliths usually measure from 1 mm to <10 mm. They rarely measure more than 15 mm, and infrequently giant salivary gland calculi >15 mm have been reported in the literature. The submandibular gland and its duct appear to be the most susceptible sites for this disease. In this article, we report two unique cases, including a giant bilateral case, measuring 50 mm in length and 5 mm in width on the right side and one, 30 mm in length, and 5 mm in width on the left side; and another case, measuring 83 mm in length...
September 2015: Dental Research Journal
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