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Hooper Index

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https://www.readbyqxmd.com/read/29188863/cross-sectional-associations-of-total-plasma-homocysteine-with-cortical-%C3%AE-amyloid-independently-and-as-a-function-of-omega-3-polyunsaturated-fatty-acid-status-in-older-adults-at-risk-of-dementia
#1
C Hooper, P De Souto Barreto, N Coley, E Caussé, P Payoux, A S Salabert, M Cesari, S Andrieu, G-L Bowman, M Weiner, B Vellas
OBJECTIVES: Elevated total plasma homocysteine is a risk factor for Alzheimer's disease (AD) and there is some evidence that omega-3 polyunsaturated fatty acids (n-3 PUFAs) can modulate the effects of homocysteine-lowering B vitamins on AD related pathologies. Hence we investigated the relationship between total plasma homocysteine and cortical β-amyloid (Aβ) in older adults at risk of dementia. The role of erythrocyte membrane n-3 PUFAs (omega 3 index) on this relationship was also explored...
2017: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/29083439/cognitive-changes-with-omega-3-polyunsaturated-fatty-acids-in-non-demented-older-adults-with-low-omega-3-index
#2
C Hooper, P De Souto Barreto, N Coley, C Cantet, M Cesari, S Andrieu, B Vellas
OBJECTIVES: To investigate the changes in specific domains of cognitive function in older adults reporting subjective memory complaints with a low omega-3 index receiving omega 3 polyunsaturated fatty acid (n-3 PUFA) supplementation or placebo. DESIGN: This is a secondary exploratory analysis of the Multidomain Alzheimer Preventive Trial (MAPT) using subjects randomized to the n-3 PUFA supplementation or placebo group. SETTING: French community dwellers aged 70 or over reporting subjective memory complaints, but free from clinical dementia...
2017: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/29064366/spot-protein-creatinine-ratio-and-spot-albumin-creatinine-ratio-in-the-assessment-of-pre-eclampsia-a-diagnostic-accuracy-study-with-decision-analytic-model-based-economic-evaluation-and-acceptability-analysis
#3
Jason Waugh, Richard Hooper, Edmund Lamb, Stephen Robson, Andrew Shennan, Fiona Milne, Christopher Price, Shakila Thangaratinam, Vladislav Berdunov, Jenn Bingham
BACKGROUND: The National Institute for Health and Care Excellence (NICE) guidelines highlighted the need for 'large, high-quality prospective studies comparing the various methods of measuring proteinuria in women with new-onset hypertensive disorders during pregnancy'. OBJECTIVES: The primary objective was to evaluate quantitative assessments of spot protein-creatinine ratio (SPCR) and spot albumin-creatinine ratio (SACR) in predicting severe pre-eclampsia (PE) compared with 24-hour urine protein measurement...
October 2017: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/28986128/vitamin-d-supplementation-to-prevent-asthma-exacerbations-a-systematic-review-and-meta-analysis-of-individual-participant-data
#4
David A Jolliffe, Lauren Greenberg, Richard L Hooper, Christopher J Griffiths, Carlos A Camargo, Conor P Kerley, Megan E Jensen, David Mauger, Iwona Stelmach, Mitsuyoshi Urashima, Adrian R Martineau
BACKGROUND: A previous aggregate data meta-analysis of randomised controlled trials showed that vitamin D supplementation reduces the rate of asthma exacerbations requiring treatment with systemic corticosteroids. Whether this effect is restricted to patients with low baseline vitamin D status is unknown. METHODS: For this systematic review and one-step and two-step meta-analysis of individual participant data, we searched MEDLINE, Embase, the Cochrane Central Register of Controlled Trials, and Web of Science for double-blind, placebo-controlled, randomised controlled trials of vitamin D3 or vitamin D2 supplementation in people with asthma that reported incidence of asthma exacerbation, published between database inception and Oct 26, 2016...
November 2017: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/28856179/gene-expression-profile-data-for-mouse-facial-development
#5
Sonia M Leach, Weiguo Feng, Trevor Williams
This article contains data related to the research articles "Spatial and Temporal Analysis of Gene Expression during Growth and Fusion of the Mouse Facial Prominences" (Feng et al., 2009) [1] and "Systems Biology of facial development: contributions of ectoderm and mesenchyme" (Hooper et al., 2017 In press) [2]. Embryonic mammalian craniofacial development is a complex process involving the growth, morphogenesis, and fusion of distinct facial prominences into a functional whole. Aberrant gene regulation during this process can lead to severe craniofacial birth defects, including orofacial clefting...
August 2017: Data in Brief
https://www.readbyqxmd.com/read/28822870/maternal-obesity-and-attention-related-symptoms-in-the-preterm-offspring
#6
Jelske W van der Burg, Elizabeth T Jensen, Margot van de Bor, Robert M Joseph, T Michael O'Shea, Karl Kuban, Elizabeth N Allred, Megan Scott, Scott Hunter, Stephen R Hooper, Olaf Dammann, Alan Leviton
BACKGROUND: Maternal pre-pregnancy obesity, in term-born children, is associated with an increased risk of attention problems, however this relationship has not been explored among children born extremely preterm. AIM: To estimate the risk of attention problems at age 10years in children born very preterm to overweight (i.e., body mass index (BMI) 25-29kg/m(2)) and obese (i.e., BMI≥30kg/m(2)) women relative to the risk among children born to women who were neither overweight nor obese (i...
August 17, 2017: Early Human Development
https://www.readbyqxmd.com/read/28704288/the-effectiveness-of-medical-simulation-in-teaching-medical-students-critical-care-medicine-a-systematic-review-and-meta-analysis
#7
Matthew David Beal, John Kinnear, Caroline Rachael Anderson, Thomas David Martin, Rachel Wamboldt, Lee Hooper
We aimed to assess effectiveness of simulation for teaching medical students critical care medicine and to assess which simulation methods were most useful. We searched AMED, EMBASE, MEDLINE, Education Resources Information Centre, British Education Index, Australian Education Index, and bibliographies and citations, in July 2013. Randomized controlled trials comparing effectiveness of simulation with another educational intervention, or no teaching, for teaching medical students critical care medicine were included...
April 2017: Simulation in Healthcare: Journal of the Society for Simulation in Healthcare
https://www.readbyqxmd.com/read/28668619/internal-training-load-and-its-longitudinal-relationship-with-seasonal-player-wellness-in-elite-professional-soccer
#8
Filipe Manuel Clemente, Bruno Mendes, Pantelis Theodoros Nikolaidis, Francisco Calvete, Sandro Carriço, Adam Lee Owen
Monitoring internal training load has been extensively used and described within team sport environments, however when compared to internal physiological measures such as heart rate (HR) and rating of perceived exertion (RPE), the literature is sparse. The primary aim of this investigation study was to assess differences of playing position on ITL, session-RPE and wellness across two different training microcycles (1 vs. 2 competitive games), in addition with examining the relationship between ITL and Hooper's Index across an entire season...
June 28, 2017: Physiology & Behavior
https://www.readbyqxmd.com/read/28437619/management-of-posterior-cruciate-ligament-tibial-avulsion-injuries-a-systematic-review
#9
Perry O Hooper, Chris Silko, Tennison L Malcolm, Lutul D Farrow
BACKGROUND: Tibial-sided avulsion injuries of the posterior cruciate ligament (PCL) generally require surgical intervention. No consensus exists concerning the optimal surgical treatment approach for these injuries. PURPOSE: To perform a systematic review investigating the open and arthroscopic surgical treatment modalities, outcomes, and complications of PCL tibial-sided bony avulsions. STUDY DESIGN: Systematic review; Level of evidence, 4...
April 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28390202/clinical-study-to-determine-the-stain-removal-effectiveness-of-a-new-dentifrice-formulation
#10
A Buelo, A Ghassemi, L Vorwerk, W Hooper, S Nathoo
OBJECTIVES: This randomized, prospective clinical trial was conducted to determine the safety and effectiveness of a new whitening dentifrice formulation in comparison to that of both a negative and a positive control dentifrice. METHODS: Seventy-nine qualifying subjects were randomly assigned to either the new whitening dentifrice (Arm & Hammer® Truly Radiant™ Clean & Fresh Toothpaste), a positive control whitening dentifrice (Crest® 3-D White® Radiant Mint Toothpaste), or a negative control regular dentifrice (Colgate® Cavity Protection Toothpaste)...
September 2016: Journal of Clinical Dentistry
https://www.readbyqxmd.com/read/28390201/comparative-plaque-removal-efficacy-of-a-new-powered-toothbrush-and-a-manual-toothbrush
#11
L Vorwerk, A Ghassemi, W Hooper, V Patel, J Milleman, K Milleman
OBJECTIVES: The purpose of this study was to determine the plaque removal effectiveness of a new powered toothbrush and compare it to that of a manual brush. METHODS: This examiner-blind, randomized study used a cross-over design. Sixty-two (62) qualifying subjects were randomly assigned either to the powered brush (Arm & Hammer Spinbrush™ Truly Radiant™ Clean & Fresh Battery-Powered Toothbrush), or a standard manual toothbrush (ADA Standard Manual Toothbrush) and instructed to brush at home with a standard fluoride toothpaste twice daily for two minutes during a one-week familiarization period...
September 2016: Journal of Clinical Dentistry
https://www.readbyqxmd.com/read/28390200/comparative-plaque-removal-efficacy-of-three-manual-toothbrushes
#12
A Ghassemi, L Vorwerk, W Hooper, M Kwang, M Naji, C R Goyal, J Qaqish
OBJECTIVES: The purpose of this study was to determine the safety and plaque-reducing effectiveness of a newly designed manual toothbrush compared to that of a leading marketed toothbrush and a reference standard manual toothbrush control. METHODS: This examiner-blind, randomized, single-use study used a cross-over design. Sixty-eight qualifying male and female subjects were randomly assigned either an Arm & Hammer™ Truly Radiant™ Deep Clean manual toothbrush (TR), a Colgate® Extra Clean manual toothbrush (C), or an ADA reference standard manual toothbrush (SM) according to one of three computer-generated sequences...
September 2016: Journal of Clinical Dentistry
https://www.readbyqxmd.com/read/28295745/does-alcohol-outlet-density-differ-by-area-level-disadvantage-in-metropolitan-perth
#13
Sarah Foster, Paula Hooper, Matthew Knuiman, Georgina Trapp, Lisa Wood
INTRODUCTION AND AIMS: Research suggests that there are area-level disparities in alcohol outlets, with greater density in disadvantaged areas. In part, this might be explained by the inequitable distribution of retail, attracted by lower rents to disadvantaged neighbourhoods. This ecological study examines the distribution of liquor licences in Perth, Australia, and whether discrepancies in the distribution of retail land-uses could account for a socio-economic gradient. DESIGN AND METHODS: Area disadvantage was determined for each Statistical Area 1 (SA1) using the Australian Bureau of Statistics Index of Relative Socio-economic Disadvantage, and licence locations were mapped in GIS...
March 13, 2017: Drug and Alcohol Review
https://www.readbyqxmd.com/read/28161533/prevalence-determinants-and-clinical-correlates-of-vitamin-d-deficiency-in-patients-with-chronic-obstructive-pulmonary-disease-in-london-uk
#14
David A Jolliffe, Wai Yee James, Richard L Hooper, Neil C Barnes, Claire L Greiller, Kamrul Islam, Angshu Bhowmik, Peter M Timms, Raj K Rajakulasingam, Aklak B Choudhury, David E Simcock, Elina Hyppönen, Robert T Walton, Christopher J Corrigan, Christopher J Griffiths, Adrian R Martineau
Vitamin D deficiency is common in patients with chronic obstructive pulmonary disease (COPD), yet a comprehensive analysis of environmental and genetic determinants of serum 25-hydroxyvitamin D (25[OH]D) concentration in patients with this condition is lacking. We conducted a multi-centre cross-sectional study in 278 COPD patients aged 41-92 years in London, UK. Details of potential environmental determinants of vitamin D status and COPD symptom control and severity were collected by questionnaire, and blood samples were taken for analysis of serum 25(OH)D concentration and DNA extraction...
February 1, 2017: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/28122658/randomised-controlled-trial-and-economic-analysis-of-an-internet-based-weight-management-programme-power-positive-online-weight-reduction
#15
Paul Little, Beth Stuart, Fd Richard Hobbs, Jo Kelly, Emily R Smith, Katherine J Bradbury, Stephanie Hughes, Peter Wf Smith, Michael V Moore, Mike Ej Lean, Barrie M Margetts, Christopher D Byrne, Simon Griffin, Mina Davoudianfar, Julie Hooper, Guiqing Yao, Shihua Zhu, James Raftery, Lucy Yardley
BACKGROUND: Behavioural counselling with intensive follow-up for obesity is effective, but in resource-constrained primary care settings briefer approaches are needed. OBJECTIVES: To estimate the clinical effectiveness and cost-effectiveness of an internet-based behavioural intervention with regular face-to-face or remote support in primary care, compared with brief advice. DESIGN: Individually randomised three-arm parallel trial with health economic evaluation and nested qualitative interviews...
January 2017: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/27920586/the-relation-between-sleep-and-weight-in-a-suburban-sleep-center-observations-and-speculations-on-apnea-and-weight
#16
Robert G Hooper
STUDY OBJECTIVES: The relationship between obstructive sleep apnea (OSA) and body weight is not clearly established. In order to describe the relationship of weight and OSA severity seen in a suburban sleep center, an observational review was performed of initial diagnostic polysomnograms (PSGs) ordered on patients with American Academy of Sleep Medicine (AASM) symptomatic indications. METHODOLOGY/PRINCIPLE FINDINGS: Initial, full-night diagnostic or initial split-night (diagnostic portion) PSGs performed for any indication on patients >18 years old were retrospectively reviewed for a two year period...
2016: Nature and Science of Sleep
https://www.readbyqxmd.com/read/27919349/familial-combined-hyperlipidemia-and-hyperlipoprotein-a-as-phenotypic-mimics-of-familial-hypercholesterolemia-frequencies-associations-and-predictions
#17
Katrina L Ellis, Jing Pang, Dick C Chan, Amanda J Hooper, Damon A Bell, John R Burnett, Gerald F Watts
BACKGROUND: A significant proportion of index cases presenting with phenotypic familial hypercholesterolemia (FH) are not found to have a pathogenic mutation and may have other inherited conditions. OBJECTIVES: Familial combined hyperlipidemia (FCHL) and elevated lipoprotein(a) [Lp(a)] may mimic FH, but the frequency and correlates of these disorders among mutation-negative FH patients have yet to be established. METHODS: The frequency of FCHL and elevated Lp(a) was investigated in 206 FH mutation-negative index cases attending a specialist lipid clinic...
November 2016: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/27900165/evaluation-of-cardiovascular-risk-lowering-health-benefits-accruing-from-laboratory-based-community-based-and-exercise-referral-exercise-programmes
#18
R Webb, J E S Thompson, J-S Ruffino, N A Davies, L Watkeys, S Hooper, P M Jones, G Walters, D Clayton, A W Thomas, K Morris, D H Llewellyn, M Ward, J Wyatt-Williams, B J McDonnell
BACKGROUND: To evaluate the ability of community-based exercise programmes to facilitate public participation in exercise and hence improved cardiovascular health, we assessed the respective impacts of: a continuously monitored exercise programme based within our university (study 1); a Valleys Regional Park-facilitated community-based outdoor exercise programme (study 2); a Wales National Exercise Referral Scheme-delivered exercise-referral programme (study 3). METHODS: Biomolecular (monocytic PPARγ target gene expression), vascular haemodynamic (central/peripheral blood pressure, arterial stiffness), clinical (insulin sensitivity, blood lipids) and anthropometric (body mass index, waist circumference, heart rate) parameters were investigated using RT-PCR, applanation tonometry, chemical analysis and standard anthropometric techniques...
2016: BMJ Open Sport & Exercise Medicine
https://www.readbyqxmd.com/read/27825992/prevalence-determinants-and-clinical-correlates-of-vitamin-d-deficiency-in-adults-with-inhaled-corticosteroid-treated-asthma-in-london-uk
#19
David A Jolliffe, Kate Kilpin, Beverley D MacLaughlin, Claire L Greiller, Richard L Hooper, Neil C Barnes, Peter M Timms, Raj K Rajakulasingam, Angshu Bhowmik, Aklak B Choudhury, David E Simcock, Elina Hyppönen, Christopher J Corrigan, Robert T Walton, Christopher J Griffiths, Adrian R Martineau
Vitamin D deficiency is common in children with asthma, and it associates with poor asthma control, reduced forced expiratory volume in one second (FEV1) and increased requirement for inhaled corticosteroids (ICS). Cross-sectional studies investigating the prevalence, determinants and clinical correlates of vitamin D deficiency in adults with asthma are lacking. We conducted a multi-centre cross-sectional study in 297 adults with a medical record diagnosis of ICS-treated asthma living in London, UK. Details of potential environmental determinants of vitamin D status, asthma control and medication use were collected by questionnaire; blood samples were taken for analysis of serum 25(OH)D concentration and DNA extraction, and participants underwent measurement of weight, height and fractional exhaled nitric oxide concentration (FeNO), spirometry and sputum induction for determination of lower airway eosinophil counts (n=35 sub-group)...
November 5, 2016: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/27514941/adolescent-femoroacetabular-impingement-gender-differences-in-hip-morphology
#20
Perry Hooper, Sameer R Oak, T Sean Lynch, Gehan Ibrahim, Ryan Goodwin, James Rosneck
PURPOSE: To compare the hip morphology of adolescent male patients and female patients who underwent hip arthroscopy for femoroacetabular impingement (FAI) and determine if gender differences exist. METHODS: We retrospectively reviewed the records of 177 adolescents, aged 13 to 18 years, who were treated for FAI with hip arthroscopy. We examined and analyzed preoperative magnetic resonance imaging (MRI) scans and plain radiographs, measuring the lateral center-edge angle, Tönnis angle, and alpha angle...
December 2016: Arthroscopy: the Journal of Arthroscopic & related Surgery
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