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esthesioneuroblastoma

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https://www.readbyqxmd.com/read/27882120/lutetium-177-dota-tate-therapy-for-esthesioneuroblastoma-a-case-report
#1
Juliano Guerra Sabongi, Mônica Carboni Pereira Gonçalves, Cira Danielle Casado Alves, João Alves, Cristovam Scapulatempo-Neto, Sonia Marta Moriguchi
Esthesioneuroblastoma (ENB), also known as olfactory neuroblastoma, is a rare malignant tumor that accounts for 3% of all tumors of the nasal cavity. The incidence of ENB is 0.4 cases per million in the general population, and the most common symptoms are nasal obstruction and epistaxis. Previous studies have indicated the presence of somatostatin receptors in this tumor type. Common treatment strategies for ENB include resection and adjuvant radiotherapy and/or chemotherapy (combined treatment); however, the rate of recurrence is high...
November 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/27715372/aggressive-esthesioneuroblastoma-with-divergent-differentiation-a-taxonomic-dilemma
#2
Norman C Charles, Carisa K Petris, Eleanore T Kim
The authors describe an esthesioneuroblastoma (olfactory neuroblastoma) that occurred within the nasal cavity and brain in a 31-year-old man. Following excision, the tumor recurred in the left orbit and in mediastinal lymph nodes. Treatment included orbital excision and systemic chemotherapy. Histopathology showed a high-grade neuroepithelial tumor with positive immunohistochemical markers for neuroendocrine and epithelial components, an unusual combination raising issues concerning taxonomy.
August 12, 2016: Orbit
https://www.readbyqxmd.com/read/27674510/definitive-radiation-in-the-treatment-of-locally-advanced-esthesioneuroblastoma-an-analysis-of-the-national-cancer-data-base
#3
N Konuthula, A M Iloreta, R M Rhome, M Posner, K Misiukiewicz, V Gupta, R L Bakst
No abstract text is available yet for this article.
October 1, 2016: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/27630897/esthesioneuroblastomas-reservations-and-recommendations
#4
Rajesh Nair, Bhavna Nayal, Vinod Kumar, Padmapriya Jaiprakash
Neuroectodermal tumour has a wide range of biological activity that ranges from an indolent course to local recurrence and rapid widespread metastasis. We describe, herewith, 2 patients with Esthesioneuroblastomas (ENB) who had varied atypical clinical presentation. The first case presented with Intracranial Pressure (ICP) headache and acute visual deterioration with radiology revealing an extra axial lesion with extension into the nasal cavity while the second case presented with nasal congestion and progressive headache of long duration...
July 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27601839/maxillofacial-esthesioneuroblastoma-a-diagnostic-complexity
#5
G Shyam Raj, Guttikonda Venkateswara Rao, Manchikatla Praveen Kumar, Kondamari Sudheerkanth
Esthesioneuroblastoma is a rare malignant tumor of the sinonasal tract. Oral and maxillofacial pathologists rarely encounter this tumor in their daily practice. Because of their complex anatomic location, non-specific symptoms, varied histomorphology and unfamiliarity, most of the times, the tumor is diagnosed as benign tumor and thereby conservative treatment results in multiple recurrences. A recurrent case of esthesioneuroblastoma in a 24-year-old female patient describing the clinical, histopathological and immunohistochemical features along with differential diagnosis is discussed...
May 2016: Journal of Oral and Maxillofacial Pathology: JOMFP
https://www.readbyqxmd.com/read/27552033/esthesioneuroblastoma-located-in-the-thoracic-extradural-space-case-report
#6
Mehmet Hüseyin Akgul, Ferruh Gezen, Ali Kemal Uzunlar
OBJECTIVE: Esthesioneuroblastoma accounted for only 6% of the malignant nasal cavity neoplasms (ENB) is a rare tumor which originates from the olfactory epithelium. ENB's are locally agresive and can metastasize by lymphatic and hematogenous routes. A patient with the mass on the nasal dorsum was reported in this article. CASE HISTORY: A 52-year-old-man admitted to the hospital with a 3 months history of progressive nasal obstruction, epistaxis and mass on the nasal dorsum...
2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27532530/extracranial-head-and-neck-neurogenic-tumors-report-of-47-cases
#7
Olfa Ben Gamra, Nadia Romdhane, Khaled Khamassi, Inès Nacef, Wafa Abid, Chiraz Chammakhi, Ines Hariga, Chiraz Mbarek
UNLABELLED: Extracranial head and neck neurogenic tumors are rare and usually revealed by histological examination. The aim of this study was to review the clinical, radiological and therapeutic particularities of these tumors. METHODS: This retrospective study concerns 47 patients with neurogenic tumors of the head and neck, operated on between 1989 and 2011 (22 years period). All patients had complete physical examination and ultrasonography was performed when a cervical extension was found...
February 2016: La Tunisie Médicale
https://www.readbyqxmd.com/read/27526015/poorly-differentiated-sinonasal-tract-malignancies-a-review-focusing-on-recently-described-entities
#8
Abbas Agaimy
Sinonasal tract malignancies are uncommon, representing no more than 5% of all head and neck neoplasms. However, in contrast to other head and neck sites, a significant proportion of sinonasal neoplasms tend to display a poorly/ undifferentiated significantly overlapping morphology and a highly aggressive clinical course, despite being of diverse histogenetic and molecular pathogenesis. The wide spectrum of poorly differentiated sinonasal epithelial neoplasms with small "basaloid" blue cell morphology includes basaloid squamous cell carcinoma (both HPV+ and HPV-unrelated), nasopharyngeal-type lymphoepithelial carcinoma (EBV+), small/large cell neuroendocrine carcinoma, esthesioneuroblastoma, poorly differentiated carcinoma of salivary type (myoepithelial carcinoma and solid adenoid cystic carcinoma), NUT midline carcinoma, the recently described SMARCB1-deficient sinonasal carcinoma, sinonasal teratocarcinosarcoma and, as a diagnosis of exclusion, sinonasal undifferentiated carcinoma (SNUC)...
2016: Ceskoslovenská Patologie
https://www.readbyqxmd.com/read/27466841/differential-diagnosis-of-chronic-rhinosinusitis-with-nasal-polyps
#9
Nyall R London, Douglas D Reh
Nasal polyps are semi-translucent mucosal outgrowths of the paranasal sinuses which typically arise in the setting of chronic rhinosinusitis (CRS). Nasal polyps are also associated with asthma, aspirin sensitivity, cystic fibrosis and allergic fungal rhinosinusitis (AFS). The majority of nasal polyps are bilateral and characterized by tissue edema and eosinophil infiltration. Patients with nasal polyps often present with complaints including nasal obstruction, congestion, rhinorrhea or altered sense of smell...
2016: Advances in Oto-rhino-laryngology
https://www.readbyqxmd.com/read/27449859/-esthesioneuroblastoma-a-single-institution-s-experience-and-general-literature-review
#10
A Lapierre, I Selmaji, H Samlali, T Brahmi, S Yossi
PURPOSE: Olfactory neuroblastoma or esthesioneuroblastoma is a rare entity among head and neck neoplasms. In this paper, we report the experience of our institution and compare it with a comprehensive review of the literature. PATIENTS AND METHODS: We retrospectively analysed clinical and treatment data of patients referred to the Lyon Sud University Hospital (France) for histologically proven olfactive esthesioneuroblastoma. RESULTS: Ten patients treated between 1993 and 2015 have been analysed...
December 2016: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
https://www.readbyqxmd.com/read/27441163/an-algorithm-for-surgical-approach-to-the-anterior-skull-base
#11
Matthew R Naunheim, Neerav Goyal, Matthew M Dedmon, Kyle J Chambers, Ahmad R Sedaghat, Benjamin S Bleier, Eric H Holbrook, William T Curry, Stacey T Gray, Derrick T Lin
OBJECTIVE: To characterize our experience with the surgical management of anterior skull base malignancy, and to propose an algorithm for surgical approach to anterior skull base malignancies. DESIGN: Retrospective review. SETTING: Academic cranial base center. PARTICIPANTS: Sixty-seven patients who underwent resection of paranasal sinus or anterior skull base malignancy with an endoscopic, cranioendoscopic, or traditional anterior craniofacial approach...
August 2016: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/27431053/smell-preservation-following-endoscopic-unilateral-resection-of-esthesioneuroblastoma-a-multi-institutional-experience
#12
Bobby A Tajudeen, Nithin D Adappa, Edward C Kuan, Joseph S Schwartz, Jeffrey D Suh, Marilene B Wang, James N Palmer
BACKGROUND: The gold standard of treatment for esthesioneuroblastoma consists of en bloc craniofacial resection with postoperative therapy dictated by histology and tumor extent. Numerous studies have shown fully endoscopic approaches to provide comparable survival and recurrence rates with decreased patient morbidity. Here we report the first multi-institutional series assessing smell outcomes of patients who underwent unilateral endoscopic resection of esthesioneuroblastoma with preservation of the contralateral olfactory bulb...
October 2016: International Forum of Allergy & Rhinology
https://www.readbyqxmd.com/read/27385200/magnetic-resonance-imaging-features-of-esthesioneuroblastoma-in-three-dogs-and-one-cat
#13
Charlotte Söffler, Antje Hartmann, Daniela Gorgas, Eberhard Ludewig, Kerstin von Pückler, Martin Kramer, Martin J Schmidt
OBJECTIVE: Esthesioneuroblastoma is a rare malignant intranasal tumor that originates from the olfactory neuroepithelium of the upper nasal cavity, and can destroy the cribriform plate and expand into the neurocranium. Descriptions of the magnetic resonance features of esthesioneuroblastomas in animals are scarce. The objectives of this study were to report the magnetic resonance imaging features of esthesioneuroblastomas in order to determine distinct imaging characteristics that may help distinguish it from other intracranial tumor types...
July 7, 2016: Tierärztliche Praxis. Ausgabe K, Kleintiere/Heimtiere
https://www.readbyqxmd.com/read/27366272/esthesioneuroblastoma-with-intracranial-extension-a-non-surgical-approach
#14
Sarah Boby Thomas, Deepak Balasubramaniam, K R Hiran, M Dinesh, K Pavithran
Esthesioneuroblastoma is a rare tumor arising from the olfactory mucosa of upper respiratory tract. The primary modality of treatment has been surgery with craniofacial resection followed by post-operative radiotherapy. There are only a few reported cases of non-surgical approaches. We report a case of esthesioneuroblastoma with intracranial extension treated with Vincristine, Adriamycin, Cyclophosphamide, Ifosfamide, Etoposide protocol followed by radiation with 5 years of follow-up. This is the first reported case using this chemotherapy schedule...
July 2016: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/27342593/-grading-of-head-and-neck-neoplasms
#15
A Agaimy, W Weichert
Tumors of the head and neck form a heterogeneous group of benign and malignant neoplasms with significant differences in biological behavior and therapeutic strategies. Squamous cell carcinomas (SCC) of the larynx, pharynx and oral cavity represent the most frequent and, thus, clinically most important malignant neoplasms in this anatomical region. Similar to other neoplasms, grading of head and neck malignancies is based on evaluation of the tumor histology usually including both architectural and cytological features; however, the current consensus grading for head and neck SCC is of limited prognostic and therapeutic value and the reproducibility is low...
July 2016: Der Pathologe
https://www.readbyqxmd.com/read/27330418/surgical-management-of-skull-base-tumors
#16
Leonardo Rangel-Castilla, Jonathan J Russin, Robert F Spetzler
AIM: To present a review of the contemporary surgical management of skull base tumors. BACKGROUND: Over the last two decades, the treatment of skull base tumors has evolved from observation, to partial resection combined with other therapy modalities, to gross total resection and no adjuvant treatment with good surgical results and excellent clinical outcomes. MATERIALS AND METHODS: The literature review of current surgical strategies and management of skull base tumors was performed and complemented with the experience of Barrow Neurological Institute...
July 2016: Reports of Practical Oncology and Radiotherapy
https://www.readbyqxmd.com/read/27256979/genetic-and-molecular-alterations-in-olfactory-neuroblastoma-implications-for-pathogenesis-prognosis-and-treatment
#17
Piotr Czapiewski, Michał Kunc, Johannes Haybaeck
Olfactory neuroblastoma (ONB, Esthesioneuroblastoma) is an infrequent neoplasm of the head and neck area derived from olfactory neuroepithelium. Despite relatively good prognosis a subset of patients shows recurrence, progression and/or metastatic disease, which requires additional treatment. However, neither prognostic nor predictive factors are well specified. Thus, we performed a literature search for the currently available data on disturbances in molecular pathways, cytogenetic changes and results gained by next generation sequencing (NGS) approaches in ONB in order to gain an overview of genetic alterations which might be useful for treating patients with ONB...
May 31, 2016: Oncotarget
https://www.readbyqxmd.com/read/27214830/septal-flip-flap-for-anterior-skull-base-reconstruction-after-endoscopic-resection-of-sinonasal-cancers-preliminary-outcomes
#18
P Battaglia, M Turri-Zanoni, F De Bernardi, P Dehgani Mobaraki, A Karligkiotis, F Leone, P Castelnuovo
Over the past decade surgery for sinonasal malignancies encroaching into the anterior skull base (ASB) has evolved from open craniofacial resection to the use of minimally invasive transnasal endoscopic approaches. Using these techniques, ASB reconstruction is most often performed in a multilayer fashion with autologous free grafts (fascia lata or iliotibial tract) which leads to the production of abundant nasal crusting in the postoperative months and discomfort for patients. In carefully selected cases, we propose harvesting a flap from the contralateral nasal septum based on the septal branches of the anterior and posterior ethmoidal arteries (Septal Flip Flap, SFF), which can be rotated to resurface the ASB defect...
June 2016: Acta Otorhinolaryngologica Italica
https://www.readbyqxmd.com/read/27165676/endoscopic-resection-of-sinonasal-malignancy-a-systematic-review-and-meta-analysis
#19
REVIEW
Rounak B Rawal, Zainab Farzal, Jerome J Federspiel, Satyan B Sreenath, Brian D Thorp, Adam M Zanation
OBJECTIVES: The use of endoscopic approaches for sinonasal malignancy resection has increased, but survival data are limited secondary to disease rarity and new surgical technique. Here we present a systematic review and meta-analysis of endoscopic endonasal resection of sinonasal malignancy. DATA SOURCES: MEDLINE, PubMed Central, NCBI Bookshelf, Cochrane Library, clinicaltrials.gov, National Guideline Clearinghouse. REVIEW METHODS: PRISMA/MOOSE guidelines were followed...
September 2016: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/27097989/bilateral-synchronous-ectopic-ethmoid-sinus-olfactory-neuroblastoma-a-case-report
#20
Elena Leon-Soriano, Carolina Alfonso, Laura Yebenes, Julio Garcia-Polo, Luis Lassaletta, Javier Gavilan
BACKGROUND: Olfactory neuroblastoma (ONB), also known as esthesioneuroblastoma, is a rare malignant head and neck cancer thought to originate from the olfactory epithelium. It typically invades contiguous structures at presentation. We report a very rare case of multifocal and ectopic ONB. CASE REPORT: A 41-year-old man presented with left nasal obstruction and occasional left epistaxis associated with headache. Endoscopic examination of the nasal cavities and computed tomography suggested bilateral polypoid masses...
April 21, 2016: American Journal of Case Reports
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