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Loss in spine height

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https://www.readbyqxmd.com/read/29112101/thoracolumbar-intervertebral-disc-area-morphometry-in-elderly-chinese-men-and-women-radiographic-quantifications-at-baseline-and-changes-at-year-4-follow-up
#1
Jùn-Qīng Wáng, Zoltán Káplár, Min Deng, James F Griffith, Jason C S Leung, Anthony Wl Kwok, Timothy Kwok, Ping Chung Leung, Yì Xiáng J Wáng
STUDY DESIGN: A population-based radiographic study with longitudinal follow-up. OBJECTIVE: To develop a quantitative index for lumbar disc space narrowing (DSN) evaluation in elderly subjects; to determine how DSN in the elderly is influenced by osteoporosis and gender. SUMMARY OF BACKGROUND DATA: There is paucity of research on quantitative classification of lumbar DSN based on disc areal morphometry. METHODS: With the database of Osteoporotic Fractures in Men (Hong Kong) and Osteoporotic Fractures in Women (Hong Kong) Studies and those who attended the year-4 follow-up (n = 1519 for men and n = 1546 for women), data of 491 women and 592 men were randomly selected...
November 3, 2017: Spine
https://www.readbyqxmd.com/read/29063365/intervertebral-disc-degeneration-an-experimental-and-numerical-study-using-a-rabbit-model
#2
Andrea Calvo-Echenique, José Cegoñino, Laura Correa-Martín, Luciano Bances, Amaya Pérez-Del Palomar
Animal models have been extensively used for the study of degenerative diseases and evaluation of new therapies to stop or even reverse the disease progression. The aim of this study is to reproduce lumbar intervertebral disc degeneration in a rabbit model by performing a percutaneous annular puncture at L4L5 level. The effect of this damage on the spine behaviour was analysed combining three different techniques: imaging processing, mechanical testing and computational modelling. Twenty New Zealand white rabbits were divided into control and experimental groups and followed up during 6 months...
October 23, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/29057346/corpectomy-and-expandable-cage-replacement-versus-third-generation-percutaneous-augmentation-system-in-case-of-vertebra-plana-rationale-and-recommendations
#3
Daniele Vanni, Andrea Pantalone, Vincenzo Magliani, Vincenzo Salini, Pedro Berjano
BACKGROUND: To evaluate the role of third generation percutaneous vertebral augmentation systems (Spine Jack(®)) as alternative to the corpectomies and expandable cages replacement (X-Core(®) Adjustable VBR System) in the treatment of vertebra plana (VP) as complication of the osteoporosis vertebral fracture (OVF). METHODS: Spine Jack(®) is a new device for mechanical kyphoplasty (MK). It is a titanium implant designed to restore the height of the vertebral body in OVF, primary or secondary bone tumors, or traumatic fractures...
September 2017: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/29019717/adding-vfa-to-dxa-identifies-fracture-risk-in-a-way-not-duplicated-by-other-measures
#4
Jay P Ginther, Ann W Ginther, Lisa D Brodersen
OBJECTIVE: Published studies have demonstrated that adding Vertebral Fracture Assessment (VFA) to Dual-energy X-ray Absorptiometry (DXA) identifies more patients with increased fracture risk than DXA alone. But who needs VFA? This study attempts to determine if some test, other than VFA, could duplicate the additional information obtained by performing VFA on ALL first-time patients. This study looked at FRAX, Height Loss, Age, documented back pain, and Non-vertebral Fragility Fractures (FFs)...
October 11, 2017: Endocrine Practice
https://www.readbyqxmd.com/read/28984540/evolution-of-the-postoperative-sagittal-spinal-profile-in-early-onset-scoliosis-is-there-a-difference-between-rib-based-and-spine-based-growth-friendly-instrumentation
#5
Zhonghui Chen, Song Li, Yong Qiu, Zezhang Zhu, Xi Chen, Liang Xu, Xu Sun
OBJECTIVE Although the vertical expandable prosthetic titanium rib (VEPTR) and growing rod instrumentation (GRI) encourage spinal growth via regular lengthening, they can create different results because of their different fixation patterns and mechanisms in correcting scoliosis. Previous studies have focused comparisons on coronal plane deformity with minimal attention to the sagittal profile. In this retrospective study, the authors aimed to compare the evolution of the sagittal spinal profile in early-onset scoliosis (EOS) treated with VEPTR versus GRI...
October 6, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28964824/spine-kinematics-exhibited-during-the-stop-jump-by-physically-active-individuals-with-adolescent-idiopathic-scoliosis-and-spinal-fusion
#6
Rumit Singh Kakar, Yumeng Li, Cathleen N Brown, Seock-Ho Kim, Timothy S Oswald, Kathy J Simpson
BACKGROUND CONTEXT: Individuals with adolescent idiopathic scoliosis post spinal fusion often return to exercise and sport. However, the movements that individuals with spinal fusion for adolescent idiopathic scoliosis (SF-AIS) use to compensate for the loss of spinal flexibility during high-effort tasks are not known. PURPOSE: The objective of this study was to compare the spinal kinematics of the trunk segments displayed during the stop-jump, a maximal effort task, between SF-AIS and healthy control groups...
September 28, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28960820/minimally-invasive-transforaminal-lumbar-interbody-fusion-and-unilateral-fixation-for-degenerative-lumbar-disease
#7
Hui-Wang Wang, Yong-Cheng Hu, Zhan-Yong Wu, Hua-Rong Wu, Chun-Fu Wu, Lian-Suo Zhang, Wei-Kun Xu, Hui-Long Fan, Jin-Sheng Cai, Jian-Qing Ma
OBJECTIVE: To evaluate the clinical effect of the minimally invasive transforaminal lumbar interbody fusion combined with posterolateral fusion and unilateral fixation using a tubular retractor in the management of degenerative lumbar disease. METHODS: A retrospective analysis was conducted to analyze the clinical outcome of 58 degenerative lumbar disease patients who were treated with minimally invasive transforaminal lumbar interbody fusion combined with posterolateral fusion and unilateral fixation during December 2012 to January 2015...
August 2017: Orthopaedic Surgery
https://www.readbyqxmd.com/read/28892125/novel-spondyloepimetaphyseal-dysplasia-due-to-ufsp2-gene-mutation
#8
M Di Rocco, M Rusmini, F Caroli, A Madeo, M Bertamino, G Marre-Brunenghi, I Ceccherini
Beukes Hip Dysplasia is an autosomal dominant disease which has to date been described only in a large South African family of Dutch origin. The patients presented with progressive epiphyseal dysplasia limited to femoral capital epiphysis and their height was not significantly reduced. A unique variant of the ubiquitin-fold modifier 1 (Ufm1)-specific peptidase 2 (UFSP2) gene (c.868T>C) has been reported in all individuals from Beukes family with clinical and radiological diagnosis of Beukes Hip Dysplasia...
September 11, 2017: Clinical Genetics
https://www.readbyqxmd.com/read/28822738/a-study-of-the-damage-behaviour-of-porcine-intervertebral-discs-in-a-bioreactor-environment
#9
M Azarnoosh, M Stoffel, B Markert
The intervertebral discs are cartilaginous, articulating structures that lie between vertebral bodies, allowing flexibility, transmission, modification, and also distribution of the forces to the spinal column. Disc degeneration is characterised by progressive loss of disc height and exaggerated radial bulging. Therefore, the spine becomes shorter, stiffer, and less mobile. In the last several decades, there is a strong need for a tissue engineering strategy that alleviates pain and restores spine function by directly addressing the underlying biological causes of disc degeneration...
August 9, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28816975/incidence-and-risk-factors-of-posterior-cage-migration-following-decompression-and-instrumented-fusion-for-degenerative-lumbar-disorders
#10
Hua Li, Hui Wang, Yanbo Zhu, Wenyuan Ding, Qian Wang
The aim of this study was to explore the incidence and risk factors for posterior cage migration (PCM) following decompression and instrumented fusion for degenerative lumbar disorders, and hope to provide references in decision making and surgical planning for spine surgeons.By retrieving the medical records from January 2011 to December 2015, 286 patients were retrospectively reviewed. According to the occurrence of PCM, patients were divided into 2 groups: PCM group and non-PCM (N-PCM). To investigate risk values for PCM, 3 categorized factors were analyzed statistically: patient characteristics: age, sex, body mass index, bone mineral density, duration of disease, diagnosis, comorbidity, smoke; surgical variables: surgery time, blood loss, surgical strategy, cage morphology, cage size, surgical segment, fusion number, source of bone graft, surgeon experience; radiographic parameters: preoperative lumbar lordosis, correction of lumbar lordosis, preoperative lumbar mobility, preoperative intervertebral height, change of intervertebral height, Modic changes, paraspinal muscle degeneration...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28781229/height-loss-was-associated-with-osteoporosis-in-korean-elderly-men-not-in-women-the-korea-national-health-and-nutrition-examination-survey-2008-2010
#11
Kyung-Sik Ahn, Chang Ho Kang, Sung Bum Cho, Kyung-Hwan Cho, Kyung-Do Han, Yong-Gyu Park, Yang-Hyun Kim
The degree of height loss varies among individuals, and excessive height loss can be a vertebral fracture or bone loss manifestation. The objective of this study was to examine the relationships between height loss and bone mineral density (BMD) and to assess the prevalence of osteoporosis according to the height loss quartiles. Data from the Korea National Health and Nutrition Examination Survey were analyzed. A total of 2799 participants more than 60 years old were included and subdivided into quartiles according to height loss (Q1-Q4)...
August 3, 2017: Journal of Clinical Densitometry
https://www.readbyqxmd.com/read/28778055/the-effect-of-the-ketogenic-diet-on-the-developing-skeleton
#12
Peter J Simm, Jillian Bicknell-Royle, Jock Lawrie, Judy Nation, Kellie Draffin, Karen G Stewart, Fergus J Cameron, Ingrid E Scheffer, Mark T Mackay
The ketogenic diet (KD) is a medically supervised, high fat, low carbohydrate and restricted protein diet which has been used successfully in patients with refractory epilepsy. Only one published report has explored its effect on the skeleton. We postulated that the KD impairs skeletal health parameters in patients on the KD. Patients commenced on the KD were enrolled in a prospective, longitudinal study, with monitoring of Dual-energy X-ray absorptiometry (DXA) derived bone parameters including bone mineral content and density (BMD)...
October 2017: Epilepsy Research
https://www.readbyqxmd.com/read/28719551/annulus-fibrosus-repair-using-high-density-collagen-gel-an-in-vivo-ovine-model
#13
Brenton Pennicooke, Ibrahim Hussain, Connor Berlin, Stephen R Sloan, Brandon Borde, Yu Moriguchi, Gernot Lang, Rodrigo Navarro-Ramirez, Jonathan Cheetham, Lawrence J Bonassar, Roger Härtl
STUDY DESIGN: Ovine in vivo study. OBJECTIVE: To perform lateral approach lumbar surgery in an ovine model to administer an injectable riboflavin (RF) cross-linked high-density collagen (HDC) gel and to assess its ability to mitigate intervertebral disc (IVD) degeneration after induced annulus fibrosus (AF) injury. SUMMARY OF BACKGROUND DATA: Biological-based injectable gels have shown efficacy in restoring biomechanical, radiographic, and histological parameters in IVD-injured animal models...
July 17, 2017: Spine
https://www.readbyqxmd.com/read/28719143/osteoporotic-vertebral-fracture-prevalence-varies-widely-between-qualitative-and-quantitative-radiological-assessment-methods-the-rotterdam-study
#14
Ling Oei, Fjorda Koromani, Stephan J Breda, John T Schousboe, Emma M Clark, Joyce Bj van Meurs, M Arfan Ikram, Jan H Waarsing, Frank Ja van Rooij, Maria C Zillikens, Gabriel P Krestin, Edwin Hg Oei, Fernando Rivadeneira
Accurate diagnosis of vertebral osteoporotic fractures is crucial for the identification of individuals at high risk of future fractures. Different methods for radiological assessment of vertebral fractures exist, but a gold standard is lacking. The aim of our study was to estimate statistical measures of agreement and prevalence of osteoporotic vertebral fractures in the population-based Rotterdam Study, across two assessment methods. The quantitative morphometry assisted by SpineAnalyzer® (QM SA) method evaluates vertebral height loss that affects vertebral shape whereas the algorithm-based qualitative (ABQ) method judges endplate integrity and includes guidelines for the differentiation of vertebral fracture and nonfracture deformities...
July 18, 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/28694597/management-of-cervical-monoradiculopathy-due-to-prolapsed-intervertebral-disc-an-institutional-experience
#15
Amresh S Bhaganagare, S A Nagesh, B G Shrihari, Vikas Naik, M N Nagarjun, Balaji S Pai
BACKGROUND: Cervical radiculopathy is the common clinical entity, often caused by "wear and tear" changes that occur in the spine. In the younger population, cervical radiculopathy is a result of a disc herniation or an acute injury causing foraminal impingement of an exiting nerve, whereas in the older individuals, it is due to foraminal narrowing from osteophyte formation, decreased disc height, and degenerative changes of the uncovertebral joints anteriorly and of the facet joints posteriorly...
April 2017: Journal of Craniovertebral Junction and Spine
https://www.readbyqxmd.com/read/28678108/the-role-of-minimally-invasive-vertebral-body-stent-on-reduction-of-the-deflation-effect-after-kyphoplasty-a-biomechanical-study
#16
Dalin Wang, Shengnai Zheng, An Liu, Jie Xu, Xiaotao Du, Yijin Wang, Liming Wang
STUDY DESIGN: Biomechanical investigation using cadaver spines. OBJECTIVE: The aim of the current study was to assess the magnitude of the deflation effect after balloon kyphoplasty (BKP) or use of minimal invasive vertebral body stent (MIVBS) in in vitro biomechanical condition. SUMMARY OF BACKGROUND DATA: Balloon kyphoplasty (BKP) is a well-established minimally invasive treatment option for osteoporotic vertebral compression fractures. However, this technique can lead to a secondary height loss-known as the "deflation effect" -causing intrasegmental kyphosis and an overall alignment failure...
July 3, 2017: Spine
https://www.readbyqxmd.com/read/28648000/-study-on-feasibility-of-enhanced-recovery-after-surgery-combined-with-mobile-microendoscopic-discectomy-transforaminal-lumbar-interbody-fusion-in-the-treatment-of-lumbar-spondylolisthesis
#17
C H Zhang, B S Yan, B S Xu, X L Ma, Q Yang, Y Liu, G M Song, R M Hu, P Li
Objective: To explore the feasibility of enhanced recovery after surgery (ERAS) combined with mobile microendoscopic discectomy-transforaminal lumbar interbody fusion (MMED-TLIF) in the treatment of lumbar spondylolisthesis and its influence on postoperative rehabilitation. Methods: From October 1 2014 to July 1 2016 , a cohort of 52 patients with lumbar spondylolisthesis who received the program of ERAS-MMED-TLIF were retrospectively reviewed in Department of Minimally Invasive Spine Surgery, Tianjin Hospital...
June 20, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28645289/degenerative-changes-of-the-canine-cervical-spine-after-discectomy-procedures-an-in-vivo-study
#18
Peter Grunert, Yu Moriguchi, Brian P Grossbard, Rodolfo J Ricart Arbona, Lawrence J Bonassar, Roger Härtl
BACKGROUND: Discectomies are a common surgical treatment for disc herniations in the canine spine. However, the effect of these procedures on intervertebral disc tissue is not fully understood. The objective of this study was to assess degenerative changes of cervical spinal segments undergoing discectomy procedures, in vivo. RESULTS: Discectomies led to a 60% drop in disc height and 24% drop in foraminal height. Segments did not fuse but showed osteophyte formation as well as endplate sclerosis...
June 23, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28589417/bone-loss-with-antiepileptic-drug-therapy-a-twin-and-sibling-study
#19
B Shiek Ahmad, S J Petty, A Gorelik, T J O'Brien, K D Hill, J J Christie, P N Sambrook, J D Wark
Changes in areal bone mineral density (aBMD) and other predictors of bone loss were evaluated in 48 same-sex twin/age-matched sibling pairs discordant for antiepileptic drug (AED) use. AED users had reduced BMD at the hip regions. Prolonged AED users had greater aBMD loss, predicting a higher risk of bone fragility. INTRODUCTION: To investigate the longitudinal associations of bone mineral measures with antiepileptic drug (AED) use, including enzyme-inducing (EIAED) and non-enzyme-inducing (NEIAED) types, and other predictors of bone loss in a study of 48 same-sex twin/age-matched sibling pairs (40 female, 8 male) discordant for AED use...
June 6, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28571219/bi-pedicle-fixation-of-affected-vertebra-in-thoracolumbar-burst-fracture
#20
Pravin Padalkar, Varshil Mehta
INTRODUCTION: Burst fractures of the spine account for 14% of all spinal injuries and more than 50% of all thoracolumbar trauma. However, there is ambiguity while choosing the right treatment plan. Short Segment Pedicle screw Fixation (SSPF) has become an increasingly popular method of treatment of thoracolumbar burst fractures, providing the advantage of incorporating fewer motion segments in the fixation. Various biomechanical studies showed that the use of pedicle screws could achieve stable construct within short-segment fixation...
April 2017: Journal of Clinical and Diagnostic Research: JCDR
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