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Eshaghali Saberi, Shahram Shahraki Zahedani, Sediqe Ebrahimipour
AIMS AND OBJECTIVES: Instrumentation techniques may cause extrusion of microorganisms and their products into the periapical region resulting inflammation and treatment failure. The aim of this ex vivo study was comparing the apical bacterial extrusion in canals prepared with single file versus multiple file rotary systems. MATERIALS AND METHODS: Ninety-two human single-rooted mandibular first premolars were used. Endodontic access cavities were prepared, and root canals were contaminated with an Enterococcus faecalis (E...
September 2017: Journal of International Society of Preventive & Community Dentistry
Naser Kalantari, Nastaran Keshavarz Mohammadi, Shahram Rafieifar, Hassan Eini-Zinab, Atefeh Aminifard, Hanieh Malmir, Narjes Ashoori, Sheyda Abdi, Maryam Gholamalizadeh, Saeid Doaei
BACKGROUND: Obesity in adolescence is the strongest risk factor for obesity in adulthood. This study aimed to evaluate the effects of a comprehensive lifestyle intervention on different anthropometric indices in 12-16-year-old boy adolescents after 12 Weeks of Intervention. METHODS: A total of 96 male adolescents from two schools participated in this study. The schools were randomly assigned to intervention (53 students) and control school (43 students). Height and weight of students were measured and their body mass index (BMI) was calculated...
2017: International Journal of Preventive Medicine
Bahram Nikmanesh, Hossein Mirhendi, Shahram Mahmoudi, Mohammad Bagher Rokni
Echinococcus granulosus is now considered a complex consisting of at least four species and ten genotypes. Different molecular targets have been described for molecular characterization of E. granulosus; however, in almost all studies only one or two of the targets have been used, and only limited data is available on the utilization of multiple loci. Therefore, we investigated the genetic diversity among 64 strains isolated from 138 cyst specimens of human and animal isolates, using a set of nuclear and mitochondrial genes; i...
October 9, 2017: Experimental Parasitology
Shahram Bolandparvaz, Mahnaz Yadollahi, Hamid Reza Abbasi, Mehrdad Anvar
Administrative data from trauma referral centers are useful sources while studying epidemiologic aspects of injuries. We aimed to provide a hospital-based view of injuries in Shiraz considering victims' age and gender, using administrative data from trauma research center.A cross-sectional registry-based study of adult trauma patients (age ≥15 years) sustaining injury through traffic accidents, violence, and unintentional incidents was conducted. Information was retrieved from 3 hospital administrative databases...
October 2017: Medicine (Baltimore)
Noor M Yassine, Jasmine T Shahram, Simon C Body
Bicuspid aortic valve (BAV) is the most common congenital valvular defect and is associated with ascending aortic dilation (AAD) in a quarter of patients. AAD has been ascribed both to the hemodynamic consequences of normally functioning and abnormal BAV morphology, and to the effect of rare and common genetic variation upon function of the ascending aortic media. AAD manifests in two overall and sometimes overlapping phenotypes: that of aortic root aneurysm, similar to the AAD of Marfan syndrome; and that of tubular AAD, similar to the AAD seen with tricuspid aortic valves (TAVs)...
2017: Frontiers in Physiology
Daryoush Shahbazi-Gahrouei, Mohsen Saeb, Shahram Monadi, Iraj Jabbari
BACKGROUND: Performing audits play an important role in quality assurance program in radiation oncology. Among different algorithms, TiGRT is one of the common application software for dose calculation. This study aimed to clinical implications of TiGRT algorithm to measure dose and compared to calculated dose delivered to the patients for a variety of cases, with and without the presence of inhomogeneities and beam modifiers. MATERIALS AND METHODS: Nonhomogeneous phantom as quality dose verification phantom, Farmer ionization chambers, and PC-electrometer (Sun Nuclear, USA) as a reference class electrometer was employed throughout the audit in linear accelerators 6 and 18 MV energies (Siemens ONCOR Impression Plus, Germany)...
2017: Advanced Biomedical Research
Hamid Solgi, Christian G Giske, Farzad Badmasti, Shadi Aghamohammad, Seyed Asghar Havaei, Shahram Sabeti, Kamyar Mostafavizadeh, Fereshteh Shahcheraghi
The emergence of carbapenem resistance among Escherichia coli is a serious threat to public health. The objective of this study was to investigate resistance genes and clonality of carbapenem resistant E. coli in Iran. Between February 2015 and July 2016, a total of 32 non-duplicate E. coli isolates that were ertapenem resistant or intermediate (R/I-ETP) were collected from patient clinical or surveillance cultures (rectal swabs) at two university hospitals. Resistance genes were identified by PCR and sequencing...
October 4, 2017: Infection, Genetics and Evolution
Mir-Shahram Safari, Javad Mirnajafi-Zadeh, Hiroyuki Hioki, Tadaharu Tsumoto
Neural circuits in the cerebral cortex consist primarily of excitatory pyramidal (Pyr) cells and inhibitory interneurons. Interneurons are divided into several subtypes, in which the two major groups are those expressing parvalbumin (PV) or somatostatin (SOM). These subtypes of interneurons are reported to play distinct roles in tuning and/or gain of visual response of pyramidal cells in the visual cortex. It remains unclear whether there is any quantitative and functional difference between the PV → Pyr and SOM → Pyr connections...
October 6, 2017: Scientific Reports
Shahram Yazdani, Mohammad Hosseinzadeh, Fakhrolsadat Hosseini
INTRODUCTION: Diagnosis lies at the heart of general practice. Every day general practitioners (GPs) visit patients with a wide variety of complaints and concerns, with often minor but sometimes serious symptoms. General practice has many features which differentiate it from specialty care setting, but during the last four decades little attention was paid to clinical reasoning in general practice. Therefore, we aimed to critically review the clinical reasoning models with a focus on the clinical reasoning in general practice or clinical reasoning of general practitioners to find out to what extent the existing models explain the clinical reasoning specially in primary care and also identity the gaps of the model for use in primary care settings...
October 2017: Journal of Advances in Medical Education & Professionalism
Mohammadbagher Rahmati, Fateme Safdarian, Mohadese Zakeri, Shahram Zare
BACKGROUND: Zinc deficiency is an important problem in children, especially in developing countries. Zinc supplements have beneficial effects on multiple factors, including treatment of growth retardation and hypogonadism, and they can be used as therapeutic and prophylactic agents against infection in children. OBJECTIVE: To determine the prevalence of zinc deficiency in 6-month to 12-year-old children in Bandar Abbas. METHODS: This study was done in Bandar Abbas in 2013...
August 2017: Electronic Physician
Shahram Tofighi, Ehsan Teymourzadeh, Majid Heydari
BACKGROUND: In order to achieve success in future goals and activities, health research centers are required to identify their key success factors. OBJECTIVE: This study aimed to extract and rank the factors affecting the success of research centers at one of the medical universities in Iran. METHODS: This study is a mixed method (qualitative-quantitative) study, which was conducted between May to October in 2016. The study setting was 22 health research centers...
August 2017: Electronic Physician
Reza Rezaei, Khosrow Hazrati Tappeh, Shahram Seyyedi, Peyman Mikaili
BACKGROUND: Leishmaniasis is a parasitic disease that appears with a range of symptoms including cutaneous, mucocutaneous, and visceral leishmaniasis. The present study sought to determine the antileishmanial effect of the extract of Artemisia dracunculus (Tarragon) compared to control treatment with pentavalent antimony (meglumine). METHODS: This experimental study was performed in 2014-2015. A. dracunculus were collected from West Azerbaijan Province, Iran and dried; then the ethanolic extract of the plant was prepared...
July 2017: Iranian Journal of Parasitology
Shahram Bamdad, Mina Bamdad, Mahsa Khanlari, Yahya Daneshbod, Behzad Khademi
In this research study, to investigate teratogenic effect of intravitreal injection of bevacizumab in pregnant rat model, twenty seven female Wistar rats were inseminated. Pregnant rats were divided into 6 groups (three groups as case and three as control groups). Each case and control groups were divided according to the day of intravitreal injections (day 2, 10 and 18). Rats in the case groups received 4 µL intravitreal injection of bevacizumab and the control groups received the same volume of distilled water...
2017: Iranian Journal of Pharmaceutical Research: IJPR
Edris Valadbeigi, Shahram Ghodsi
A series of N-[2-(8-metoxy-2H-chromen-2-one)ethyl] piperazinyl quinolones containing a carbonyl related functional groups (oxo or oxyimino) on the ethyl spacer of coumarin and piperazin rings was synthesized and studied for their antibacterial and antifungal activities . The synthesis of compounds (6a-6l) was achieved through the versatile and efficient synthetic route that involved reaction of quinolones with appropriately α- bromo ketone or α- bromo oxime derivatives (2, 2a-c). The structures of the new compounds were confirmed by IR, Mass, (1)H-NMR and (13)C-NMR spectra...
2017: Iranian Journal of Pharmaceutical Research: IJPR
Priscilla Lai, Zhongli Cai, Jean-Philippe Pignol, Eli Lechtman, Shahram Mashouf, Yijie Lu, Mitchell A Winnik, David A Jaffray, Raymond M Reilly
Permanent seed implantation (PSI) brachytherapy is a highly conformal form of radiation therapy but is challenged with dose inhomogeneity due to its utilization of low energy radiation sources. Gold nanoparticles (AuNP) conjugated with electron emitting radionuclides have recently been developed as a novel form of brachytherapy and can aid in homogenizing dose through physical distribution of radiolabeled AuNP when injected intratumorally (i.t.) in suspension. However, the distribution is unpredictable and precise placement of many injections would be difficult...
October 4, 2017: Physics in Medicine and Biology
Shahram Gooran, Mohammad Reza Khajavi, Amir Javid, Sanaz Dehghani, Elnaz Kheiri, Ali Mohammad Fakhr Yaseri, Gholamreza Pourmand
OBJECTIVE: Our objective was to investigate vein blood gas levels in the transplanted kidney during surgery as a predictive factor for delayed graft function after renal transplant. MATERIALS AND METHODS: Sixty patients with renal transplant were enrolled in our study from January 2015 to January 2016. After vessels were declamped posttransplant, blood samples from the transplanted kidney veins were taken and acidosis and oxygenation in these samples were measured...
September 30, 2017: Experimental and Clinical Transplantation
Vahid Nourani, Shahram Mousavi, Fahreddin Sadikoglu, Vijay P Singh
This study developed a new hybrid artificial intelligence (AI)-meshless approach for modeling contaminant transport in porous media. The key innovation of the proposed approach is that both black box and physically-based models are combined for modeling contaminant transport. The effectiveness of the approach was evaluated using experimental and real world data. Artificial neural network (ANN) and adaptive neuro-fuzzy inference system (ANFIS) were calibrated to predict temporal contaminant concentrations (CCs), and the effect of noisy and de-noised data on the model performance was evaluated...
September 21, 2017: Journal of Contaminant Hydrology
Ladan Dastgheib, Narjes Pishva, Nasrin Saki, Soghra Khabnadideh, Bahareh Kardeh, Fatemeh Torabi, Shahram Arabnia, Alireza Heiran
Diaper dermatitis is a common disorder. Coriandrum sativum is a herbal remedy with anti-inflammatory, analgesic, anti-microbial and anti-oxidant activities effects. In this non randomised clinical trial which was performed on 58 infants with diaper dermatitis referred to Faghihi Hospital, Shiraz University of Medical Sciences, the efficacy and safety of topical Coriandrum extract cream is compared with hydrocortisone ointment. Coriandrum sativum extract cream was administered for 37 (intervention group) and hydrocortisone 1% ointment for 21 (control group) patients...
August 2017: Malaysian Journal of Medical Sciences: MJMS
Amiran Dzutsev, Alison Hogg, Yongjun Sui, Shahram Solaymani-Mohammadi, Huifeng Yu, Blake Frey, Yichuan Wang, Jay A Berzofsky
Mechanisms that imprint T cell homing to the small intestine have been well studied; however, those for homing to the colon are poorly understood. Recently, we found that these are distinct subcompartments of the gut mucosal immune system, which implies differential homing. Here, we show that colonic CD11c(+) APCs imprint CD8(+) T cell preferential homing to the colon, in contrast to those from the small intestine that imprint CD8(+) T cell homing to the small intestine, and that the differences are related to the variable ability of APCs to induce α4β7-integrin and CCR9 expression on T cells...
September 26, 2017: Journal of Leukocyte Biology
Ali Fadaie Kermani, Reza Derakhshani, Shahram Shafiei Bafti
Morphotectonic indices by representing the longer period of time than recorded earthquake data, are useful in evaluating the tectonic activity of a region. Dashtkhak area is located in Kerman province of Iran, where one of the most active faults, Kouhbanan strike slip fault, passes through. This data article provides a precise level data on mountain fronts and valleys of Dashtkhak region that is fundamental for morphotectonic investigations of the relationship among geomorphology and tectonic activity. This data is valuable in the field of geology and geography...
October 2017: Data in Brief
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