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https://www.readbyqxmd.com/read/29139647/is-increased-facial-asymmetry-associated-with-the-use-of-hormonal-contraceptive-among-polish-young-women-in-wroclaw
#1
Slawomir Koziel, Raja Chakraborty, Dariusz Danel, Krzysztof Borysławski
Fluctuating asymmetry (FA) is the small random deviations from a perfect bilateral symmetry in a morphological trait. It is considered as an indicator of biological quality and developmental stability of individual. Adverse environmental conditions and high levels of sex steroids may increase FA. Symmetry in women was found to be related with phases of the menstrual cycles (MC). This cross sectional study aimed to compare facial symmetry between women using and not using hormonal contraceptives with reference to the phases of their fertile and non-fertile phases of MC...
March 2017: Collegium Antropologicum
https://www.readbyqxmd.com/read/29139352/-contraception-for-young-women-with-focus-on-long-acting-reversible-contraceptives
#2
EDITORIAL
Pernille Ravn, Kresten Rubeck Petersen
Long-acting, reversible contraceptives are about 20 times more effective in terms of contraceptive efficacy than oral hormonal contraceptives, patch or vaginal ring are. Long-acting, reversible contraceptives are not associated with serious adverse events but induce changes in menstrual bleeding pattern in about 75% of the users. The progestogen intrauterine device is effective in the treatment of menor-rhagia and dysmenorrhoea. Increased use of long-acting reversible contraceptives is expected to reduce unplanned pregnancies and legal abortions in all ages...
November 13, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/29139115/risk-of-stroke-associated-with-use-of-estrogen-containing-contraceptives-in-women-with-migraine-a-systematic-review
#3
REVIEW
Huma U Sheikh, Jelena Pavlovic, Elizabeth Loder, Rebecca Burch
OBJECTIVE: Migraine with aura has been associated with increased risk of ischemic and hemorrhagic stroke. Prior studies have shown a further increase in risk in women using combined hormonal contraceptives (CHCs). This has led to guidelines recommending against use of CHCs in this population. We sought to assess whether the risk of stroke is associated with the dose of estrogen and whether there is evidence of synergism between migraine and CHCs. We also sought to assess whether an interaction effect exists between migraine and CHCs...
November 15, 2017: Headache
https://www.readbyqxmd.com/read/29135292/-male-hormonal-contraception-past-present-future
#4
Norbert Pásztor, Borbála Eszter Hegyi, Attila Badó, Gábor Németh
In certain regions of the world the enormous rate of population growth raises economic and public health concerns and widely accessible contraceptive methods would be desired. In contrast, in other countries the use of effective contraception is a question of individual preferences. Today, most of the reliable contraceptive methods are applied by women, while the options for male methods are quite limited. It is well known that significant portion of pregnancies are still unplanned and several data revealed men's willingness to take part in family planning...
November 2017: Orvosi Hetilap
https://www.readbyqxmd.com/read/29133111/effect-of-oral-contraception-on-anemia-in-12-low-and-middle-income-countries
#5
S Bellizzi, M M Ali
CONTEXT: In low and middle-income countries anaemia is a major public health issue in women of reproductive age for a series of factors including iron deficiency. OBJECTIVE: To estimate prevalence of anemia and to assess the association of low level of haemoglobin versus duration of use of oral contraceptives (OC). METHODS: Demographic and health survey (DHS) of 12 countries, conducted between 2005 and 2012, were analyzed. The status of anemia was separately evaluated for non-pregnant women using OC for at least six months, one year, and two years, and for women using no method of contraception and/or using non-hormonal contraception...
November 10, 2017: Contraception
https://www.readbyqxmd.com/read/29133081/-medical-treatment-of-endometriosis-hormonal-treatment-of-pain-impact-on-evolution-and-future-perspectives
#6
Sophie Geoffron, Guillaume Legendre, Emile Daraï, Nathalie Chabbert-Buffet
CONTEXT: Endometriosis is a chronic painful disease, for which hormone therapy is usually offered as a first line option to women not willing to conceive. OBJECTIVES: To analyse and synthesize the literature, from 2006 onwards, on pain control, and disease evolution in oemn using combined hormonal contraceptives, progestins and GnRH analogs. Data on other current and future treatment perspectives is included as well. SOURCES: Medline (Pubmed), the Cochrane Library, and endometriosis treatment recommendations published by European Society of Human Reproduction and Embryology (ESHRE), National Institute for health and Care Excellence (NICE), American College of Obstetricians and Gynecologists (ACOG), Royal College of Obstetricians and Gynaecologists (RCOG) and Société des Obstétriciens et Gynécologues du Canada (SOGC)...
November 10, 2017: La Presse Médicale
https://www.readbyqxmd.com/read/29132172/can-screening-and-confirmatory-testing-in-the-management-of-patients-with-primary-aldosteronism-be-improved
#7
Michael Stowasser, Ashraf Ahmed, Zeng Guo, Martin Wolley, Jacobus Ungerer, Brett McWhinney, Marko Poglitsch, Richard Gordon
Widespread application of the plasma aldosterone/renin ratio (ARR) as a screening test has led to the recognition that primary aldosteronism (PA) is the most common specifically treatable and potentially curable form of hypertension, accounting for 5-10% of patients. Maximal detection requires accurate diagnostic approaches and awareness and control of factors that confound results, including most antihypertensives, posture, time of day, dietary salt, and plasma potassium. Recent studies have revealed potential for false positives in patients on beta-adrenoceptor blockers, and, when direct renin concentration (but not plasma renin activity) is used to measure renin, in women during the luteal phase of the menstrual cycle or receiving estrogen-containing contraceptives or hormonal replacement therapy...
November 13, 2017: Hormone and Metabolic Research, Hormon- und Stoffwechselforschung, Hormones et Métabolisme
https://www.readbyqxmd.com/read/29130574/drug-interactions-between-rifamycin-antibiotics-and-hormonal-contraception-a-systematic-review
#8
Katharine B Simmons, Lisa B Haddad, Kavita Nanda, Kathryn M Curtis
BACKGROUND: Rifamycin antibiotics are commonly used for treatment of tuberculosis, but may reduce effectiveness of hormonal contraception (HC). OBJECTIVES: To determine whether interactions between rifamycins and HC result in decreased effectiveness or increased toxicity of either therapy. SEARCH STRATEGY: We searched MEDLINE, Embase, Cochrane and clinicaltrials. gov through May, 2017. SELECTION CRITERIA: We included trials, cohort, and case-control studies addressing pregnancy rates, pharmacodynamics, or pharmacokinetic (PK) outcomes when HC and rifamycins were administered together versus apart...
November 12, 2017: BJOG: An International Journal of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/29127865/which-information-on-women-s-issues-in-epilepsy-does-a-community-pharmacist-need-to-know-a-delphi-consensus-study
#9
Ramzi Shawahna
OBJECTIVE: The aim of this study was to develop and achieve consensus on a core list of important knowledge items that community pharmacists should know on women's issues in epilepsy. METHODS: This was a consensual study using a modified Delphi technique. Knowledge items were collected from the literature and from nine key contacts who were interviewed on their views on what information community pharmacists should have on women's issues in epilepsy. More knowledge items were suggested by five researchers with interest in women's issues who were contacted to rate and comment on the knowledge items collected...
November 8, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29111911/trends-in-long-acting-reversible-contraceptive-larc-use-larc-use-predictors-and-dual-method-use-among-a-national-sample-of-college-women
#10
Eric R Walsh-Buhi, Hannah L Helmy
OBJECTIVE: Assess long-acting reversible contraceptive (LARC) and other contraceptive use trends, identify LARC use predictors, and examine dual method use. PARTICIPANTS: Females in the American College Health Association-National College Health Assessment (ACHA-NCHA) II, aged 18-24 years, who reported having vaginal sex (N = 37,899). METHODS: Secondary analyses of Fall 2011-2014 ACHA-NCHA II data. RESULTS: Statistically significant increases in LARC usage and, specifically, implant usage, were found...
November 7, 2017: Journal of American College Health: J of ACH
https://www.readbyqxmd.com/read/29111902/the-effect-of-cranberry-juice-consumption-on-the-recurrence-of-urinary-tract-infection-relationship-to-baseline-risk-factors
#11
Kevin C Maki, Kristin M Nieman, Arianne L Schild, Kerrie L Kaspar, Christina Khoo
OBJECTIVE: The objective of this study was to assess relationships between clinical predictors of urinary tract infection (UTI) and effects of cranberry juice consumption on recurrence in a post hoc analysis of a 24-week, randomized, double-blind, placebo-controlled, multicenter clinical trial in women with a recent history of UTI. METHODS: Participants consumed a cranberry (n = 185) or placebo (n = 188) beverage (240 mL) daily. Odds ratios (OR) from 20 candidate predictor variables were evaluated in univariate analyses to assess clinical UTI incidence relationships in the placebo group...
November 7, 2017: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/29111860/identification-of-the-gender-specific-health-needs-of-women-following-lung-transplantation
#12
Emily E Robertson, Robin J Bell, Penelope J Robinson, Greg Snell, Bronwyn Levvey, Helen M Whitford, Jane Harris, Susan R Davis
BACKGROUND: Little is known of the prevalence and severity of menstrual dysfunction, climacteric symptoms, pelvic floor disorders, sexual problems, and psychological wellbeing after lung transplantation in women. MATERIALS AND METHODS: Adult female lung transplant recipients, attending the Alfred Hospital Lung Transplant Service in Melbourne, Australia participated in a women's health, cross-sectional questionnaire-based study. RESULTS: The 123 of 149 potential participants were recruited between September 2014 and July 2015...
November 7, 2017: Journal of Women's Health
https://www.readbyqxmd.com/read/29111146/medical-contraindications-to-estrogen-and-contraceptive-use-among-women-veterans
#13
Colleen P Judge, Xinhua Zhao, Florentina E Sileanu, Maria K Mor, Sonya Borrero
BACKGROUND: Women veterans have high rates of medical comorbidities and may be particularly vulnerable to adverse health outcomes associated with unintended pregnancy. OBJECTIVES: The objective of the study was to estimate the prevalence of medical contraindications to estrogen-containing combined hormonal contraception among women veterans of reproductive age and to evaluate the relationship between contraindications and contraceptive use. STUDY DESIGN: This was a secondary analysis of data from a cross-sectional, telephone-based survey with a national sample of 2302 female veterans, aged 18-45 years, who use the Veterans Administration Healthcare System for primary care...
October 27, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29105931/medroxyprogesterone-acetate-treated-human-primary-endometrial-epithelial-cells-reveal-unique-gene-expression-signature-linked-to-innate-immunity-and-hiv-1-susceptibility
#14
Matthew W Woods, Muhammad Atif Zahoor, Sara Dizzell, Chris P Verschoor, Charu Kaushic
PROBLEM: Medroxyprogesterone acetate (MPA), a progestin-based hormonal contraceptive designed to mimic progesterone, has been linked to increased human immunodeficiency virus (HIV-1) susceptibility. Genital epithelial cells (GECs) form the mucosal lining of the female genital tract (FGT) and provide the first line of protection against HIV-1. The impact of endogenous sex hormones or MPA on the gene expression profile of GECs has not been comprehensively documented. METHOD OF STUDY: Using microarray analysis, we characterized the transcriptional profile of primary endometrial epithelial cells grown in physiological levels of E2, P4, and MPA...
November 6, 2017: American Journal of Reproductive Immunology: AJRI
https://www.readbyqxmd.com/read/29097362/elevated-plasma-factor-ixa-activity-in-premenopausal-women-on-hormonal-contraception
#15
Pansakorn Tanratana, Paul Ellery, Pamela Westmark, Alan E Mast, John P Sheehan
OBJECTIVE: Combined oral contraceptives induce a reversible hypercoagulable state with an enhanced risk of venous thromboembolism, but the underlying mechanism(s) remain unclear. Subjects on combined oral contraceptives also demonstrate a characteristic resistance to APC (activated protein C) in the thrombin generation assay. Here, we report the potential role of plasma factor IXa (FIXa) as a mechanism for hormone-induced systemic hypercoagulability. APPROACH AND RESULTS: A novel assay was used to determine FIXa activity in plasma samples from volunteer blood donors...
November 2, 2017: Arteriosclerosis, Thrombosis, and Vascular Biology
https://www.readbyqxmd.com/read/29097225/effects-of-concurrent-vaginal-miconazole-treatment-on-the-absorption-and-exposure-of-nestorone%C3%A2-segesterone-acetate-and-ethinyl-estradiol-delivered-from-a-contraceptive-vaginal-ring-a-randomized-crossover-drug-drug-interaction-study
#16
Katharine B Simmons, Narender Kumar, Marlena Plagianos, Kevin Roberts, Elena Hoskin, Leo Han, Mohcine Alami, George Creasy, Bruce Variano, Ruth Merkatz
OBJECTIVES: To evaluate the effects of concurrent administration of three vaginal miconazole nitrate formulations on the absorption and exposure of Nestorone® (segesterone acetate) and ethinyl estradiol from a novel contraceptive vaginal ring (NES/EE CVR). STUDY DESIGN: This was an open-label, randomized, crossover, drug-drug interaction study conducted over three menstrual cycles in healthy women with regular menses. We compared systemic exposure to NES and EE by determining area under the curve (AUC8-21d) with CVR-only and CVR with each miconazole treatment...
October 30, 2017: Contraception
https://www.readbyqxmd.com/read/29096570/pharmacist-intentions-to-prescribe-hormonal-contraception-following-new-legislative-authority-in-california
#17
Kevin Vu, Sally Rafie, Kate Grindlay, Hialy Gutierrez, Daniel Grossman
OBJECTIVE: Following a California law expanding pharmacists' scope of practice to include directly providing self-administered hormonal contraception to patients pursuant to a statewide protocol, this study aimed to assess California pharmacists' intentions to provide this new service prior to the protocol development and implementation. DESIGN: Descriptive, nonexperimental, cross-sectional study. SETTING: California between August and September 2014...
January 1, 2017: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/29092828/how-we-treat-heavy-menstrual-bleeding-associated-with-anticoagulants
#18
Kochawan Boonyawat, Sarah H O'Brien, Shannon M Bates
Anticoagulant-associated heavy menstrual bleeding (HMB) is an underrecognized but not uncommon problem in clinical practice. Premenopausal women should be advised of the potential effect of anticoagulant therapy on menstrual bleeding at the time of treatment initiation. Consequences of HMB should be assessed and treated on an ongoing basis. In the acute setting, the decision to withhold anticoagulants is based on an individual patient's risk of thrombosis and the severity of the bleeding. For women who require long-term anticoagulation, the use of levonorgestrel intrauterine system, tranexamic acid (during menstrual flow), high dose progestin-only therapy, and combined hormonal contraceptives are effective for controlling HMB; the risk of thrombosis during anticoagulant therapy with these treatments is not well studied, but is likely to be low...
November 1, 2017: Blood
https://www.readbyqxmd.com/read/29091478/contraception-and-breastfeeding-at-4-months-postpartum-among-women-intending-to-breastfeed
#19
Alison N Goulding, Kathryn Wouk, Alison M Stuebe
OBJECTIVE: To estimate the association between postpartum contraception and breastfeeding among women intending to breastfeed. METHODS: We analyzed data from the Infant Feeding Practices Study II, a prospective cohort study of U.S. mothers (2005-2007). Among 1,349 women with prenatal intention to breastfeed at least 4 months who reported contraception use 3 months postpartum, we used multivariable logistic regression to estimate odds and predicted probabilities of breastfeeding by contraceptive category...
November 1, 2017: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/29082726/-differential-diagnosis-and-management-of-abnormal-uterine-bleeding-in-adolescence
#20
Tiziano Motta, Antonio S Laganà, Gaetano Valenti, Valentina L LA Rosa, Marco Noventa, Amerigo Vitagliano, Benito Chiofalo, Agnese M Rapisarda, Diego Rossetti, Salvatore G Vitale
Abnormal uterine bleeding (AUB) is defined as any atypical genital bleeding originating from the uterine cavity, without the characteristics of normal menstrual period. AUB is an important symptom both for adolescents and their parents, and it usually leads to a state of anxiety. Although about 95% of AUB could be considered as a dysfunctional disorder, AUB requires well-defined diagnostic procedures in order to detect a physical cause, ruling out complex or systemic diseases, including oncological ones. Diagnostic procedures require the acquisition of a full and detailed history, and it is also crucial to obtain as much compliance from the patient as possible...
December 2017: Minerva Ginecologica
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