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https://www.readbyqxmd.com/read/29165810/insecticide-susceptibility-status-in-mexican-populations-of-stegomyia-aegypti-%C3%A2-aedes-aegypti-a-nationwide-assessment
#1
P A Kuri-Morales, F Correa-Morales, C González-Acosta, M Moreno-Garcia, R Santos-Luna, S Román-Pérez, F Salazar-Penagos, M Lombera-González, G Sánchez-Tejeda, J F González-Roldán
In Mexico, mosquito vector-borne diseases are of public health concern as a result of their impact on human morbidity and mortality. The use of insecticides against adult mosquitoes is one of the most common ways of controlling mosquito population densities. However, the use of these compounds has resulted in the development of insecticide resistance. The aim of this study was to estimate susceptibility to six pyrethroids, two carbamates and two organophosphates in Mexican populations of Stegomyia aegypti (Linnaeus, 1762) (= Aedes aegypti) (Diptera: Culicidae) mosquitoes...
November 22, 2017: Medical and Veterinary Entomology
https://www.readbyqxmd.com/read/29163079/neural-correlates-of-rewarded-response-inhibition-in-youth-at-risk-for-problematic-alcohol-use
#2
Brenden Tervo-Clemmens, Alina Quach, Beatriz Luna, William Foran, Tammy Chung, Michael D De Bellis, Duncan B Clark
Risk for substance use disorder (SUD) is associated with poor response inhibition and heightened reward sensitivity. During adolescence, incentives improve performance on response inhibition tasks and increase recruitment of cortical control areas (Geier et al., 2010) associated with SUD (Chung et al., 2011). However, it is unknown whether incentives moderate the relationship between response inhibition and trait-level psychopathology and personality features of substance use risk. We examined these associations in the current project using a rewarded antisaccade (AS) task (Geier et al...
2017: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/29162980/functional-studies-of-ccaat-enhancer-binding-protein-site-located-downstream-of-the-transcriptional-start-site
#3
Yujie Liu, Michael R Nonnemacher, Aikaterini Alexaki, Vanessa Pirrone, Anupam Banerjee, Luna Li, Evelyn Kilareski, Brian Wigdahl
Previous studies have identified a CCAAT/enhancer binding protein (C/EBP) site located downstream of the transcriptional start site (DS3). The role of the DS3 element with respect to HIV-1 transactivation by Tat and viral replication has not been characterized. We have demonstrated that DS3 was a functional C/EBPβ binding site and mutation of this site to the C/EBP knockout DS3-9C variant showed lower HIV-1 long terminal repeat (LTR) transactivation by C/EBPβ. However, it was able to exhibit similar or even higher transcription levels by Tat compared to the parental LTR...
2017: Clinical Medicine Insights. Pathology
https://www.readbyqxmd.com/read/29161488/identifying-trypanosoma-cruzi-discreet-typing-units-in-triatomines-collected-in-different-natural-regions-of-per%C3%A3%C2%BA
#4
Carlos P Padilla, Uriel Alvarado, Gladis Ventura, Deysi Luna-Caipo, Marcial Suárez, José R Tuñoque, Nancy Ruelas-Llerena, Luis A Fachín, Alina Huiza, Lizandro Gonzáles, Julio César Carranza, Gustavo Adolfo Vallejo, Gustavo Adolfo Vallejo, Abraham G Cáceres, Abraham G Cáceres
INTRODUCTION: Trypanosoma cruzi has been divided by international consensus into six discrete typing units (DTU): TcI, TcII, TcIII, TcIV, TcV y TcVI. The factors determining the dynamics of T. cruzi genotypes vector transmission of Chagas' disease in the different geographical regions of Perú are still unknown. OBJECTIVE: To detect and type T. cruzi DTUs from the faeces of seven species of triatomines (Panstrongylus chinai, P. geniculatus, P. herreri, Rhodnius robustus, R...
March 29, 2017: Biomédica: Revista del Instituto Nacional de Salud
https://www.readbyqxmd.com/read/29160848/application-of-enzymatic-extracts-from-a-calb-standard-strain-as-biocatalyst-within-the-context-of-conventional-biodiesel-production-optimization
#5
Carlos Luna, Diego Luna, Felipa M Bautista, Rafael Estevez, Juan Calero, Alejandro Posadillo, Antonio A Romero, Enrique D Sancho
The application of biocatalysts in the transesterification process of triglycerides (TG) allows integrating the glycerol in the form of monoglyceride (MG), sharply increasing the yield and the environmental sustainability of the conventional biodiesel production process. This is known as Ecodiesel. To overcome the inconvenient of the high cost of the currently employed highly purified commercial enzymes, the use of scarcely purified extracts obtained from standard strains of the same species of commercial lipases currently applied in this process is being investigated...
November 21, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29160722/do-infection-patterns-of-human-papillomavirus-affect-the-cytologic-detection-of-high-grade-cervical-lesions-on-papanicolaou-tests
#6
Siavash Azadmanesh Samimi, Roxanne R Mody, Steven Goodman, Eric Luna, Donna Armylagos, Mary R Schwartz, Dina R Mody, Yimin Ge
CONTEXT: - Persistent infection with high-risk human papillomavirus (hrHPV) is the major cause of cervical cancer. The effect of HPV infection patterns on cytologic detection of cervical lesions is unknown. OBJECTIVE: - To determine the effect of HPV infection patterns on the sensitivity of cytologic detection of high-grade cervical lesions. DESIGN: - Papanicolaou tests from 257 women with biopsy-confirmed, high-grade squamous intraepithelial lesions were analyzed with respect to HPV infection patterns...
November 21, 2017: Archives of Pathology & Laboratory Medicine
https://www.readbyqxmd.com/read/29160487/educational-practices-of-nursing-in-the-puerperium-social-representations-of-puerperal-mothers
#7
Hilana Dayana Dodou, Tamires Daianny Araújo de Oliveira, Mônica Oliveira Batista Oriá, Dafne Paiva Rodrigues, Patrícia Neyva da Costa Pinheiro, Izaildo Tavares Luna
OBJECTIVE: To understand the social representations of puerperal women regarding the contents of the educational practices carried out by nursing in the puerperium. METHOD: Descriptive and qualitative study, carried out from June to September 2014, in Fortaleza, Ceará State, Brazil. Nineteen puerperal women were administered a semi-structured interview. The Theory of Social Representations was used as a theoretical reference. Lexical analysis was performed with ALCESTE (version 2012) software...
November 2017: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/29157632/appendicular-deciduosis-as-a-cause-of-acute-abdomen
#8
Alexis Luna Aufroy, Ruth Orellana Fernández, Mariona Novell Grau, Joan Carles Ferreres Piñas, Salvador Navarro Soto
No abstract text is available yet for this article.
November 17, 2017: Cirugía Española
https://www.readbyqxmd.com/read/29153568/maternal-obesity-and-cardiac-development-in-the-offspring-study-in-human-neonates-and-minipigs
#9
Maria Angela Guzzardi, Tiziana Liistro, Luna Gargani, Lamia Ait Ali, Gennaro D'Angelo, Silvia Rocchiccioli, Federica La Rosa, Alessandra Kemeny, Elena Sanguinetti, Nadia Ucciferri, Mariarosaria De Simone, Antonietta Bartoli, Pierluigi Festa, Piero A Salvadori, Silvia Burchielli, Rosa Sicari, Patricia Iozzo
OBJECTIVES: The aim of this study was to investigate the consequences of maternal overweight on cardiac development in offspring in infants (short term) and minipigs (short and longer term). BACKGROUND: The epidemic of overweight involves pregnant women. The uterine environment affects organ development, modulating disease susceptibility. Offspring of obese mothers have higher rates of cardiovascular events and mortality. METHODS: Echocardiography was performed in infants born to lean and overweight mothers at birth and at 3, 6, and 12 months of age...
November 10, 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29146808/extended-gamma-ray-sources-around-pulsars-constrain-the-origin-of-the-positron-flux-at-earth
#10
A U Abeysekara, A Albert, R Alfaro, C Alvarez, J D Álvarez, R Arceo, J C Arteaga-Velázquez, D Avila Rojas, H A Ayala Solares, A S Barber, N Bautista-Elivar, A Becerril, E Belmont-Moreno, S Y BenZvi, D Berley, A Bernal, J Braun, C Brisbois, K S Caballero-Mora, T Capistrán, A Carramiñana, S Casanova, M Castillo, U Cotti, J Cotzomi, S Coutiño de León, C De León, E De la Fuente, B L Dingus, M A DuVernois, J C Díaz-Vélez, R W Ellsworth, K Engel, O Enríquez-Rivera, D W Fiorino, N Fraija, J A García-González, F Garfias, M Gerhardt, A González Muñoz, M M González, J A Goodman, Z Hampel-Arias, J P Harding, S Hernández, A Hernández-Almada, J Hinton, B Hona, C M Hui, P Hüntemeyer, A Iriarte, A Jardin-Blicq, V Joshi, S Kaufmann, D Kieda, A Lara, R J Lauer, W H Lee, D Lennarz, H León Vargas, J T Linnemann, A L Longinotti, G Luis Raya, R Luna-García, R López-Coto, K Malone, S S Marinelli, O Martinez, I Martinez-Castellanos, J Martínez-Castro, H Martínez-Huerta, J A Matthews, P Miranda-Romagnoli, E Moreno, M Mostafá, L Nellen, M Newbold, M U Nisa, R Noriega-Papaqui, R Pelayo, J Pretz, E G Pérez-Pérez, Z Ren, C D Rho, C Rivière, D Rosa-González, M Rosenberg, E Ruiz-Velasco, H Salazar, F Salesa Greus, A Sandoval, M Schneider, H Schoorlemmer, G Sinnis, A J Smith, R W Springer, P Surajbali, I Taboada, O Tibolla, K Tollefson, I Torres, T N Ukwatta, G Vianello, T Weisgarber, S Westerhoff, I G Wisher, J Wood, T Yapici, G Yodh, P W Younk, A Zepeda, H Zhou, F Guo, J Hahn, H Li, H Zhang
The unexpectedly high flux of cosmic-ray positrons detected at Earth may originate from nearby astrophysical sources, dark matter, or unknown processes of cosmic-ray secondary production. We report the detection, using the High-Altitude Water Cherenkov Observatory (HAWC), of extended tera-electron volt gamma-ray emission coincident with the locations of two nearby middle-aged pulsars (Geminga and PSR B0656+14). The HAWC observations demonstrate that these pulsars are indeed local sources of accelerated leptons, but the measured tera-electron volt emission profile constrains the diffusion of particles away from these sources to be much slower than previously assumed...
November 17, 2017: Science
https://www.readbyqxmd.com/read/29145754/cortical-and-subcortical-brain-morphometry-differences-between-patients-with-autism-spectrum-disorder-and-healthy-individuals-across-the-lifespan-results-from-the-enigma-asd-working-group
#11
Daan van Rooij, Evdokia Anagnostou, Celso Arango, Guillaume Auzias, Marlene Behrmann, Geraldo F Busatto, Sara Calderoni, Eileen Daly, Christine Deruelle, Adriana Di Martino, Ilan Dinstein, Fabio Luis Souza Duran, Sarah Durston, Christine Ecker, Damien Fair, Jennifer Fedor, Jackie Fitzgerald, Christine M Freitag, Louise Gallagher, Ilaria Gori, Shlomi Haar, Liesbeth Hoekstra, Neda Jahanshad, Maria Jalbrzikowski, Joost Janssen, Jason Lerch, Beatriz Luna, Mauricio Moller Martinho, Jane McGrath, Filippo Muratori, Clodagh M Murphy, Declan G M Murphy, Kirsten O'Hearn, Bob Oranje, Mara Parellada, Alessandra Retico, Pedro Rossa, Katya Rubia, Devon Shook, Margot Taylor, Paul M Thompson, Michela Tosetti, Gregory L Wallace, Fengfeng Zhou, Jan K Buitelaar
OBJECTIVE: Neuroimaging studies show structural differences in both cortical and subcortical brain regions in children and adults with autism spectrum disorder (ASD) compared with healthy subjects. Findings are inconsistent, however, and it is unclear how differences develop across the lifespan. The authors investigated brain morphometry differences between individuals with ASD and healthy subjects, cross-sectionally across the lifespan, in a large multinational sample from the Enhancing Neuroimaging Genetics Through Meta-Analysis (ENIGMA) ASD working group...
November 17, 2017: American Journal of Psychiatry
https://www.readbyqxmd.com/read/29145024/direct-analysis-of-ethylene-glycol-in-human-serum-on-the-basis-of-analyte-adduct-formation-and-liquid-chromatography-tandem-mass-spectrometry
#12
Marek Dziadosz
The aim of this work was to develop a fast, cost-effective and time-saving liquid chromatography-tandem mass spectrometry (LC-MS/MS) analytical method for the analysis of ethylene glycol (EG) in human serum. For these purposes, the formation/fragmentation of an EG adduct ion with sodium and sodium acetate was applied in the positive electrospray mode for signal detection. Adduct identification was performed with appropriate infusion experiments based on analyte solutions prepared in different concentrations...
November 12, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/29143238/yeasts-and-bacterial-biosurfactants-as-demulsifiers-for-petroleum-derivative-in-seawater-emulsions
#13
Fernanda Cristina P Rocha E Silva, Bruno Augusto C Roque, Nathalia Maria P Rocha E Silva, Raquel D Rufino, Juliana M Luna, Valdemir A Santos, Ibrahim M Banat, Leonie A Sarubbo
Oil sludge or waste generated in transport, storage or refining forms highly stable mixtures due to the presence and additives with surfactant properties and water forming complex emulsions. Thus, demulsification is necessary to separate this residual oil from the aqueous phase for oil processing and water treatment/disposal. Most used chemical demulsifiers, although effective, are environmental contaminants and do not meet the desired levels of biodegradation. We investigated the application of microbial biosurfactants as potential natural demulsifiers of petroleum derivatives in water emulsions...
November 15, 2017: AMB Express
https://www.readbyqxmd.com/read/29137828/differentiating-between-clinical-and-behavioral-phenotypes-in-first-episode-psychosis-during-maintenance-of-visuospatial-working-memory
#14
Maria Jalbrzikowski, Vishnu P Murty, Patricia L Stan, Jusmita Saifullan, Daniel Simmonds, William Foran, Beatriz Luna
INTRODUCTION: We probed the neural basis of working memory in individuals with first episode of psychosis (FEP) and assessed how these neural abnormalities are associated with behavioral performance and/or core to psychosis pathophysiology. METHODS: FEP (N=35) and matched controls (N=25) performed a visuospatial working memory task during fMRI acquisition. We isolated neural activity during the maintenance period and examined neural activity within regions typically engaged during a working memory task...
November 11, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/29133888/neuronal-hyperactivity-due-to-loss-of-inhibitory-tone-in-apoe4-mice-lacking-alzheimer-s-disease-like-pathology
#15
Tal Nuriel, Sergio L Angulo, Usman Khan, Archana Ashok, Qiuying Chen, Helen Y Figueroa, Sheina Emrani, Li Liu, Mathieu Herman, Geoffrey Barrett, Valerie Savage, Luna Buitrago, Efrain Cepeda-Prado, Christine Fung, Eliana Goldberg, Steven S Gross, S Abid Hussaini, Herman Moreno, Scott A Small, Karen E Duff
The ε4 allele of apolipoprotein E (APOE) is the dominant genetic risk factor for late-onset Alzheimer's disease (AD). However, the reason APOE4 is associated with increased AD risk remains a source of debate. Neuronal hyperactivity is an early phenotype in both AD mouse models and in human AD, which may play a direct role in the pathogenesis of the disease. Here, we have identified an APOE4-associated hyperactivity phenotype in the brains of aged APOE mice using four complimentary techniques-fMRI, in vitro electrophysiology, in vivo electrophysiology, and metabolomics-with the most prominent hyperactivity occurring in the entorhinal cortex...
November 13, 2017: Nature Communications
https://www.readbyqxmd.com/read/29133194/effect-of-native-and-minimally-modified-low-density-lipoprotein-on-the-activation-of-monocyte-subsets
#16
Francisco Blanco-Favela, José Esteban Espinosa-Luna, Adriana Karina Chávez-Rueda, Alejandra Madrid-Miller, Luis Chávez-Sánchez
BACKGROUND: In atherosclerosis, monocytes are essential and secrete pro-inflammatory cytokines in response to modified low-density lipoprotein (LDL). Human CD14(++)CD16(-), CD14(++)CD16(+) and CD14(+)CD16(++) monocytes produce different cytokines. The objective of this research was to determine the number of monocyte subsets positives to cytokines in response to native (nLDL) and minimally modified LDL (mmLDL). METHODS: Human monocytes from healthy individuals were purified by negative selection and were stimulated with nLDL, mmLDL or LPS...
November 10, 2017: Archives of Medical Research
https://www.readbyqxmd.com/read/29128927/toll-like-receptors-participate-in-naegleria-fowleri-recognition
#17
Moisés Martínez-Castillo, Leopoldo Santos-Argumedo, José Manuel Galván-Moroyoqui, Jesús Serrano-Luna, Mineko Shibayama
Naegleria fowleri is a protozoan that invades the central nervous system and causes primary amoebic meningoencephalitis. It has been reported that N. fowleri induces an important inflammatory response during the infection. In the present study, we evaluated the roles of Toll-like receptors in the recognition of N. fowleri trophozoites by human mucoepithelial cells, analyzing the expression and production of innate immune response mediators. After amoebic interactions with NCI-H292 cells, the expression and production levels of IL-8, TNF-α, IL-1β, and human beta defensin-2 were evaluated by RT-PCR, ELISA, immunofluorescence, and dot blot assays, respectively...
November 11, 2017: Parasitology Research
https://www.readbyqxmd.com/read/29128914/simultaneous-determination-of-tolterodine-and-its-two-metabolites-5-hydroxymethyltolterodine-and-n-dealkyltolterodine-in-human-plasma-using-lc-ms-ms-and-its-application-to-a-pharmacokinetic-study
#18
Young-Hoon Kim, Ji-Yeong Byeon, Se-Hyung Kim, Choong-Min Lee, Eui Hyun Jung, Won Ki Chae, Choon-Gon Jang, Seok-Yong Lee, Yun Jeong Lee
Tolterodine is a nonselective muscarinic antagonist that is indicated for the overactive urinary bladder and other urinary difficulties. We developed and validated a simple, rapid and sensitive high-performance liquid chromatography analytical method utilizing tandem mass spectrometry (LC-MS/MS) for the quantitation of tolterodine and its major metabolites, 5-hydroxymethyltolterodine (5-HMT) and N-dealkyltolterodine (NDT), in human plasma. After liquid-liquid extraction with methyl t-butyl ether, chromatographic separation of the three analytes was achieved using a reversed-phase Luna Phenyl-hexyl column (100 × 2...
November 11, 2017: Archives of Pharmacal Research
https://www.readbyqxmd.com/read/29125988/quantification-of-nitrogenous-bases-dna-and-collagen-type-i-for-the-estimation-of-the-postmortem-interval-in-bone-remains
#19
Cristina Pérez-Martínez, María D Pérez-Cárceles, Isabel Legaz, Gemma Prieto-Bonete, Aurelio Luna
Estimating the postmortem interval (PMI) is an important goal in forensic medicine and continues to be one of the most difficult tasks of the forensic investigator. Few accurate methods exist to determine the time since death of skeletonized human remains due to the great number of intrinsic and external factors that may alter the normal course of postmortem change. The purpose of this research was to assess the usefulness of various biochemical parameters, such as nitrogenous bases (adenine, guanine, purines, cytosine, thymine, pyrimidines, hypoxanthine and xanthine), DNA and Collagen Type I peptides to estimate PMI...
November 4, 2017: Forensic Science International
https://www.readbyqxmd.com/read/29120808/alternative-oil-extraction-methods-from-echium-plantagineum-l-seeds-using-advanced-techniques-and-green-solvents
#20
Natalia Castejón, Pilar Luna, Francisco J Señoráns
The edible oil processing industry involves large losses of organic solvent into the atmosphere and long extraction times. In this work, fast and environmentally friendly alternatives for the production of echium oil using green solvents are proposed. Advanced extraction techniques such as Pressurized Liquid Extraction (PLE), Microwave Assisted Extraction (MAE) and Ultrasound Assisted Extraction (UAE) were evaluated to efficiently extract omega-3 rich oil from Echium plantagineum seeds. Extractions were performed with ethyl acetate, ethanol, water and ethanol:water to develop a hexane-free processing method...
April 1, 2018: Food Chemistry
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