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https://www.readbyqxmd.com/read/29302150/the-forgotten-plague-psychiatric-manifestations-of-ebola-zika-and-emerging-infectious-diseases
#1
REVIEW
Veronica Tucci, Nidal Moukaddam, Jonathan Meadows, Suhal Shah, Sagar C Galwankar, G Bobby Kapur
The media and public health generally focus on the biological and physical ramifications of epidemics. Mental health issues that coincide with emerging diseases and epidemics are rarely examined and sometimes, even eschewed due to cultural considerations. Psychiatric manifestations of various infectious diseases, especially with a focus on Ebola Virus disease (EVD) and Zika Virus, are discussed in this commentary to illustrate the continued need of care after the resolution of the actual illness. Various infectious diseases have associations with mental illness, such as an increased risk of obsessive-compulsive disorders and Tourette syndrome in children with Group B streptococcal infection...
October 2017: Journal of Global Infectious Diseases
https://www.readbyqxmd.com/read/29297112/relationship-among-hiv-related-stigma-mental-health-and-quality-of-life-for-hiv-positive-patients-in-tehran
#2
Mehrnaz Rasoolinajad, Nasrin Abedinia, Ahmad Ali Noorbala, Minoo Mohraz, Banafsheh Moradmand Badie, Abdulqader Hamad, Leyla Sahebi
People living with HIV/AIDS (PLHA) face several challenges in terms of the medical management of their disease. Alongside this are stigma, discrimination and psychosocial issues associated with HIV infection. In this study, the relationships associated with HIV-related stigma, mental health and quality of life for HIV-positive patients were investigated. This cross-sectional study examined a sample of 450 HIV positive patients from the Infectious Diseases and Behavioral Health Clinic of Imam Khomeini Hospital in the city of Tehran, Iran...
January 2, 2018: AIDS and Behavior
https://www.readbyqxmd.com/read/29230208/ramadan-fasting-exerts-immunomodulatory-effects-insights-from-a-systematic-review
#3
Mohammad Adawi, Abdulla Watad, Stav Brown, Khadija Aazza, Hicham Aazza, Mohamed Zouhir, Kassem Sharif, Khaled Ghanayem, Raymond Farah, Hussein Mahagna, Stefano Fiordoro, Samir Giuseppe Sukkar, Nicola Luigi Bragazzi, Naim Mahroum
Ramadan is the ninth month of the Islamic lunar calendar and is observed by Muslims as a month of fasting. All Muslim adults are expected to fast; nevertheless certain subgroups, including sick, frail subjects, and pregnant women, among others, are exempted. Ramadan fasting has been shown to impact on body systems in different manners. The influence of Ramadan fasting on immune system regulation remains elusive; however, immune system changes, such as the modulation of body response to various infectious, stressful, and other harmful events, are of great interest during fasting...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/29230022/trained-innate-immunity-a-salient-factor-in-the-pathogenesis-of-neuroimmune-psychiatric-disorders
#4
A P Salam, A Borsini, P A Zunszain
Historically, only cells of the adaptive immune system have been considered capable of retaining memory for infectious challenges. Recently, however, cells of the innate immune system have been shown to be capable of displaying long-term functional memory following a single immunostimulatory challenge, leading to enhanced production of proinflammatory molecules upon other subsequent, and temporally distant, immunostimulatory challenges. This effect has been termed 'trained innate immunity', and is underwritten by stable epigenetic changes in immune and metabolic pathways...
December 12, 2017: Molecular Psychiatry
https://www.readbyqxmd.com/read/29214003/no-molecular-evidence-of-borna-disease-virus-among-schizophrenia-and-bipolar-disorder-patients-in-iran
#5
Somayeh Shatizadeh-Malekshahi, Hamid Reza Ahmadkhaniha, Seyed Jalal Kiani, Ahmad Nejati, Leila Janani, Jila Yavarian
Background and Objectives: Viruses have been suggested as one of the risk factors for psychiatric disorders. Among infectious agents Borna disease virus (BDV) has been known as a neurotropic virus which is able to cause neurological disorders in different animals. Recently there were controversial findings about BDV association with pathogenesis of human psychotic disorders. Materials and Methods: Here we performed a nested reverse transcription polymerase chain reaction for detection of BDV P40 RNA in peripheral blood mononuclear cell samples of schizophrenia (SC), bipolar disorder (BD) patients and healthy controls (HCs)...
April 2017: Iranian Journal of Microbiology
https://www.readbyqxmd.com/read/29165223/health-status-of-asylum-seekers-spain
#6
Núria Serre-Delcor, Carlos Ascaso, Antoni Soriano-Arandes, Francisco Collazos Sanchez, Begoña Treviño Maruri, Elena Sulleiro, Diana Pou Ciruelo, Cristina Bocanegra Garcia, Israel Molina Romero
The rising rate of conflicts and the unsafe situation caused by reasons of ethnicity, religion, gender, sexual orientation, political opinion, or nationality entail an increase in the number of migratory movements. The goal of this article is to describe the health status of asylum seekers visited in an international health center. We conducted a retrospective study of the asylum seekers visited between July 2013 and June 2016. A total of 303 cases were included. The median age was 28.0 years (interquartile range [IQR]: 21-35), and 203 (67...
November 20, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29128324/overlooked-fatal-infectious-diseases-after-long-term-antipsychotic-use-in-patients-with-psychiatric-illness
#7
Liliang Li, Xing Ye, Ziqin Zhao, Pan Gao, Yan Jiang
No abstract text is available yet for this article.
November 8, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/29115723/patterns-of-paediatric-emergency-presentations-to-a-tertiary-referral-centre-in-the-northern-territory
#8
Davina Buntsma, Anna Lithgow, Evan O'Neill, Didier Palmer, Peter Morris, Jason Acworth, Franz E Babl
OBJECTIVE: To describe epidemiological data concerning paediatric attendances at the ED of Royal Darwin Hospital (RDH). METHODS: We conducted a retrospective cohort study of paediatric emergency presentations to the RDH ED during 2004 and 2013. Epidemiological data, including demographics, admission rates and diagnostic grouping, were analysed using descriptive and comparative statistical methods. We compared data with findings from a baseline epidemiological study by the Paediatric Research in Emergency Departments International Collaborative (PREDICT) conducted in 2004...
November 8, 2017: Emergency Medicine Australasia: EMA
https://www.readbyqxmd.com/read/29115073/assessment-of-competence-in-emergency-medicine-among-healthcare-professionals-in-cameroon
#9
Sang Chul Kim, Young Sun Ro, Sang Do Shin, Dae Han Wi, Joongsik Jeong, Ju Ok Park, Kyong Min Sun, Kwangsoo Bae
Development of a competence-based curriculum is important. This study aimed to develop competence assessment tools in emergency medicine and use it to assess competence of Cameroonian healthcare professionals. This was a cross-sectional, descriptive study. Through literature review, expert survey, and discrimination tests, we developed a self-survey questionnaire and a scenario-based competence assessment tool for assessing clinical knowledge and self-confidence to perform clinical practices or procedures. The self-survey consisted of 23 domains and 94 questionnaires on a 5-point Likert scale...
December 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29102489/cause-specific-mortality-in-adults-with-atopic-dermatitis
#10
Jacob P Thyssen, Lone Skov, Alexander Egeberg
BACKGROUND: Adult atopic dermatitis (AD) has been associated with several co-morbidities, but cause-specific mortality risk is unknown. OBJECTIVES: To examine cause-specific death rates and risk in adults with AD. METHODS: We performed cross-linkage of nationwide health care and cause of death registers. Adult patients with AD were matched with 10 controls per study subject. We calculated incidence rates per 1,000 person-years and hazard ratios (HRs) of cause-specific death with 95% confidence intervals (95% CIs) using Cox proportional hazards models...
November 1, 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/29099544/catatonia-update
#11
Kanwarjeet Brar, Sachin S Kaushik, Steven Lippmann
Catatonia is a neuropsychiatric condition characterized by physical presentations ranging from profound immobility to excessive motor activity. Emotional aspects of catatonia vary clinically between psychomotor retardation and extreme excitability. In the past, catatonia was considered to be a variant of schizophrenia. However, the disorder actually occurs as a clinical expression of many different psychiatric, neurologic, or medical diagnoses. A prompt diagnostic evaluation should identify any underlying diseases with consideration of somatic pathologies, especially those affecting central nervous system function...
October 26, 2017: Primary Care Companion to CNS Disorders
https://www.readbyqxmd.com/read/29084290/exploring-differences-in-healthcare-utilization-of-prisoners-in-the-canton-of-vaud-switzerland
#12
Karine Moschetti, Véra Zabrodina, Pierre Stadelmann, Tenzin Wangmo, Alberto Holly, Jean-Blaise Wasserfallen, Bernice S Elger, Bruno Gravier
Prison healthcare is an important public health concern given the increasing healthcare needs of a growing and aging prison population, which accumulates vulnerability factors and suffers from higher disease prevalence than the general population. This study identifies the key factors associated with outpatient general practitioner (GP), nursing or psychiatric healthcare utilization (HCU) within prisons. Cross-sectional data systematically collected by the prison medical staff were obtained for a sample of 1664 adult prisoners of the Canton of Vaud, Switzerland, for the year 2011...
2017: PloS One
https://www.readbyqxmd.com/read/29083100/mefloquine-for-preventing-malaria-during-travel-to-endemic-areas
#13
REVIEW
Maya Tickell-Painter, Nicola Maayan, Rachel Saunders, Cheryl Pace, David Sinclair
BACKGROUND: Mefloquine is one of four antimalarial agents commonly recommended for preventing malaria in travellers to malaria-endemic areas. Despite its high efficacy, there is controversy about its psychological side effects. OBJECTIVES: To summarize the efficacy and safety of mefloquine used as prophylaxis for malaria in travellers. SEARCH METHODS: We searched the Cochrane Infectious Diseases Group Specialized Register; the Cochrane Central Register of Controlled Trials (CENTRAL), published on the Cochrane Library; MEDLINE; Embase (OVID); TOXLINE (https://toxnet...
October 30, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29068607/relationship-between-toxoplasmosis-and-schizophrenia-a-review
#14
REVIEW
Aleksander J Fuglewicz, Patryk Piotrowski, Anna Stodolak
A growing body of evidence suggests a correlation between schizophrenia and exposure to infectious agents. The majority of studied cases concerns the infection caused by T. gondii, an obligatory intracellular parasite that infects about 1/3 of the entire human population, according to the available data. The acute stage of the disease, predominantly short-lived and transient, transforms into the latent and chronic phase in which the parasite localizes within tissue cysts, mainly in the central nervous system...
September 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/29065368/bbox1-is-down-regulated-in-maternal-immune-activated-mice-and-implicated-in-genetic-susceptibility-to-human-schizophrenia
#15
Hwayoung Lee, Hyung-Ki Kim, Jun-Tack Kwon, Shohyun Park, Hae Jeong Park, Su Kang Kim, Jin Kyung Park, Won Sub Kang, Young Jong Kim, Joo-Ho Chung, Jong Woo Kim, Hak-Jae Kim
Prenatal exposure to infectious or inflammatory insults can increase the risk of developing neuropsychiatric disorders such as bipolar disorder, autism, and schizophrenia in later life. Gamma-butyrobetaine hydroxylase (BBOX 1) is an enzyme responsible for the biosynthesis of l-carnitine, a key molecule in fatty acid metabolism. This cytosolic dimeric protein belongs to the dioxygenase family. In this study, we investigated whether BBOX 1 expression was related to psychiatric disorder in an animal model. We also conducted a case-control study using 284 schizophrenia patients and 409 controls with single-nucleotide polymorphisms (SNPs) in the 5'-near region of BBOX 1...
January 2018: Psychiatry Research
https://www.readbyqxmd.com/read/28961664/cns-drug-development-lessons-learned-part-3-psychiatric-and-central-nervous-system-drugs-developed-over-the-last-decade-implications-for-the-field
#16
Sheldon H Preskorn
This column reviews the divergence between the approach to drug development in infectious disease, oncology, and immunology versus psychiatry. Between 2009 and 2016, 254 new drugs were approved. Of those, only 9 were for a psychiatric indication; another 5 were labeled to treat central nervous system disorders that are not considered psychiatric per se but are frequently found in individuals with psychiatric illnesses (eg, substantial weight gain). There were 2 additional new products for psychiatric indications that involved either a combination product (Contrave) or a prodrug for the production of aripiprazole (Aristada)...
September 2017: Journal of Psychiatric Practice
https://www.readbyqxmd.com/read/28912822/a-rare-case-of-cavitary-lesion-of-the-lung-caused-by-mycoplasma-pneumoniae-in-an-immunocompetent-patient
#17
Muhammad Kashif, Rizwan Ahmed Dudekula, Misbahuddin Khaja
Mycoplasma pneumoniae is an atypical bacterium that most commonly causes upper respiratory tract infections, but it can also cause pneumonia, referred to as "walking pneumonia." Although cavitary lesions are present in a wide variety of infectious and noninfectious processes, those attributable to M. pneumoniae are extremely uncommon; thus, to date, epidemiological studies are lacking. Here, we present a rare case of a 20-year-old male, referred to us from a psychiatric facility for evaluation of a cough, who was found to have a cavitary lesion in the right upper lobe...
2017: Case Reports in Medicine
https://www.readbyqxmd.com/read/28899580/the-interplay-between-cytokines-and-the-kynurenine-pathway-in-inflammation-and-atherosclerosis
#18
Roland Baumgartner, Maria J Forteza, Daniel F J Ketelhuth
The kynurenine pathway (KP) is the major metabolic route of tryptophan (Trp) metabolism. Indoleamine 2,3-dioxygenase (IDO1), the enzyme responsible for the first and rate-limiting step in the pathway, as well as other enzymes in the pathway, have been shown to be highly regulated by cytokines. Hence, the KP has been implicated in several pathologic conditions, including infectious diseases, psychiatric disorders, malignancies, and autoimmune and chronic inflammatory diseases. Additionally, recent studies have linked the KP with atherosclerosis, suggesting that Trp metabolism could play an essential role in the maintenance of immune homeostasis in the vascular wall...
September 9, 2017: Cytokine
https://www.readbyqxmd.com/read/28852251/cyclical-vomiting-syndrome-psychiatrist-s-view-point
#19
D Vijaya Raghavan, V Vimal Doshi, Shanthi Nambi
Cyclical vomiting syndrome (CVS) is an idiopathic functional disorder characterized by recurrent episodes of nausea and vomiting separated by symptom-free intervals. Even though initially described in children, it is seen in all age groups. Exact etiology is not known. Various physical, infectious, and psychosocial stressors have been implicated for CVS. High incidence of psychiatric comorbidities such as panic attacks, anxiety disorder, and depression is seen in CVS. Most children outgrow CVS with time though some may transition to migraine or continue to have CVS as adults...
July 2017: Indian Journal of Psychological Medicine
https://www.readbyqxmd.com/read/28826513/slicing-the-cortex-to-study-mental-illness-alois-alzheimer-s-pictures-of-equivalence
#20
Lara Keuck
Alois Alzheimer (1864-1915) was a German physician who specialized in psychiatry, and who is today known for the first description of a-in his own words-peculiar ailment (eigenartige Erkrankung), which was named after him. In his time, however, he was foremost recognized for his work in refining histopathological techniques and thereby contributing to the methodological arsenal for differential diagnosis in clinical psychiatry. In his laboratory that was based at the renowned Munich Psychiatric University Clinic led by Emil Kraepelin (1856-1926), Alzheimer, his assistants, and students conserved, prepared, and studied slices of deceased patients' brains under the microscope...
2017: Progress in Brain Research
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