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https://www.readbyqxmd.com/read/27930661/chronic-diseases-health-behaviors-and-demographic-characteristics-as-predictors-of-ill-health-retirement-findings-from-the-korea-health-panel-survey-2008-2012
#1
Young Joong Kang, Mo-Yeol Kang
PURPOSE: The research aim was to identify demographic characteristics, chronic diseases, and unhealthy behaviors predicting ill health retirement in South Korea. METHODS: Data were collected from 15,407 individuals enrolled in the first through the fifth phases of the Korea Health Panel Survey (2008-2012) using structured questionnaires examining retirement, morbidities, and health-related behaviors. The Cox proportional hazard model was used to examine demographic and clinical characteristics' effects on ill health retirement...
2016: PloS One
https://www.readbyqxmd.com/read/27922168/update-of-the-swiss-guidelines-on-post-treatment-lyme-disease-syndrome
#2
Johannes Nemeth, Enos Bernasconi, Ulrich Heininger, Mohamed Abbas, David Nadal, Carol Strahm, Stefan Erb, Stefan Zimmerli, Hansjakob Furrer, Julie Delaloye, Thierry Kuntzer, Ekkehard Altpeter, Mathias Sturzenegger, Rainer Weber, For The Swiss Society For Infectious Diseases And The Swiss Society For Neurology
Lyme borreliosis is caused by Borrelia burgdorferi sensu lato infection, which responds well to antibiotic therapy in the overwhelming majority of cases. However, despite adequate antibiotic treatment some patients report persisting symptoms which are commonly summarised as post-treatment Lyme disease syndrome (PTLDS). In 2005, the Swiss Society of Infectious Diseases published a case definition for PTLDS. We aimed to review the scientific literature with a special emphasis on the last 10 years, questioning whether the definitions from 2005 are still valid in the light of current knowledge...
2016: Swiss Medical Weekly
https://www.readbyqxmd.com/read/27856235/infection-and-inflammation-in-schizophrenia-and-bipolar-disorder
#3
Teppei Tanaka, Taro Matsuda, Lindsay N Hayes, Shuojia Yang, Katrina Rodriguez, Emily G Severance, Robert H Yolken, Akira Sawa, William Eaton
The present study investigated the relationship between exposure to infectious agents and inflammation markers in individuals with schizophrenia (SZ), bipolar disorder (BP), and controls without a psychiatric disorder. We measured plasma levels of antibodies and innate immune markers and correlated them with clinical symptoms and cognitive function. In both SZ and BP, we found an increase in soluble CD14, and in BP an increase in C-reactive protein, IgM class antibodies against cytomegalovirus (CMV), and IgG class antibodies against herpes simplex virus 2...
November 14, 2016: Neuroscience Research
https://www.readbyqxmd.com/read/27852256/health-conditions-of-inmates-in-italy
#4
Fabio Voller, Caterina Silvestri, Gianrocco Martino, Eleonora Fanti, Giorgio Bazzerla, Fabio Ferrari, Marco Grignani, Sandro Libianchi, Antonio Maria Pagano, Franco Scarpa, Cristina Stasi, Teresa Di Fiandra
BACKGROUND: Several studies have shown that prison is characterized by a higher prevalence of chronic diseases than unconfined settings. The aim of this study was to describe the characteristics and health of inmates, focusing on internal diseases. METHODS: We designed a specific clinical record using the Python programming language. We considered all of the diagnoses according to the ICD-9-CM. RESULTS: Of a total of 17,086 inmates, 15,751 were enrolled in our study (M = 14,835; F = 869), corresponding to 92...
November 16, 2016: BMC Public Health
https://www.readbyqxmd.com/read/27828693/a-register-based-case-control-study-of-prescription-medication-utilization-in-binge-eating-disorder
#5
Hunna J Watson, Andreas Jangmo, Melissa A Munn-Chernoff, Laura M Thornton, Elisabeth Welch, Camilla Wiklund, Yvonne von Hausswolff-Juhlin, Claes Norring, Barry K Herman, Henrik Larsson, Cynthia M Bulik
OBJECTIVE: Individuals with binge-eating disorder (BED) experience psychiatric and somatic comorbidities and obesity, but the nature and magnitude of prescription medication utilization is unclear. We investigated utilization using Swedish registry data and a case-control design. METHODS: Cases were identified from Riksät and Stepwise longitudinal registers and were individuals diagnosed with BED per DSM-IV-TR criteria between July 1, 2006, and December 31, 2009, at eating disorder clinics (n = 238, 96% female, mean age = 22...
July 7, 2016: Primary Care Companion to CNS Disorders
https://www.readbyqxmd.com/read/27704388/primary-care-screening-methods-and-outcomes-for-asylum-seekers-in-new-york-city
#6
Nathan S Bertelsen, Elizabeth Selden, Polina Krass, Eva S Keatley, Allen Keller
Effective screening in primary care among asylum-seekers in the US is critical as this population grows. This study aimed to evaluate disease prevalence and screening methods in this high-risk group. Two hundred ten new clients from 51 countries, plus Tibet, who were accepted into a program for asylum seekers from 2012 to 2014 were included. Screening rates and outcomes for infectious, non-communicable, and mental illnesses were evaluated. Screening rates were highest for PTSD, depression, hepatitis B, and latent tuberculosis...
October 4, 2016: Journal of Immigrant and Minority Health
https://www.readbyqxmd.com/read/27652003/long-term-poor-rapport-lack-of-spontaneity-and-passive-social-withdrawal-related-to-acute-post-infectious-encephalitis-a-case-report
#7
Atsurou Yamada, Nobuhiro Miyachi, Toshiyasu Miura, Masako Suzuki, Norio Watanabe, Tatsuo Akechi
INTRODUCTION: Post-infectious encephalitis/encephalopathy is a neurological syndrome that sometimes develops following common viral or bacterial infections. The most common form is acute disseminated encephalomyelitis (ADEM). ADEM is a demyelinating disease of the central nervous system that typically presents as a monophasic disorder associated with multifocal neurologic symptoms and encephalitis. Anti-N-methyl-d-aspartate receptor (anti-NMDAR) encephalitis is another type of severe autoimmune disorder, characterized by seizures, movement disorders and psychiatric symptoms...
2016: SpringerPlus
https://www.readbyqxmd.com/read/27648506/pyrotherapy-for-the-treatment-of-psychosis-in-the-21st-century-a-case-report-and-literature-review
#8
Zachary D Zuschlag, Callie J Lalich, Edward B Short, Mark Hamner, David A Kahn
The concept that fevers can improve the condition of patients with certain medical and psychiatric diseases dates back to Hippocrates. Over the centuries, it has been observed that fevers and infectious agents have been beneficial for a broad spectrum of diseases, including neurologic conditions such as epilepsy and psychiatric illnesses including melancholy and psychosis. Interest in the concept of fever as a treatment for disease, termed pyrotherapy or pyretotherapy, peaked in the late 1800s and early 1900s thanks to the Nobel Prize winning work of Julius Wagner-Jauregg for his studies with malaria therapy for general paralysis of the insane, now more commonly referred to as neurosyphilis...
September 2016: Journal of Psychiatric Practice
https://www.readbyqxmd.com/read/27621774/rationale-and-design-of-the-cardiorespiratory-fitness-and-hospitalization-events-in-armed-forces-study-in-eastern-taiwan
#9
Gen-Min Lin, Yi-Hwei Li, Chung-Jen Lee, Jeng-Chuan Shiang, Ko-Huan Lin, Kai-Wen Chen, Yu-Jung Chen, Ching-Fen Wu, Been-Sheng Lin, Yun-Shun Yu, Felicia Lin, Fung-Ying Su, Chih-Hung Wang
AIM: To investigate the association between cardiorespiratory fitness and hospitalization events in a cohort of large voluntary arm forces in Taiwan. METHODS: The cardiorespiratory fitness and hospitalization events in armed forces (CHIEF) is a retrospective cohort consisting of more than 4000 professional military members aged 18-50 years in Eastern Taiwan. All participants received history taking, physical examination, chest radiography, 12-lead electrocardiography, blood tests for cell counts and fasting glucose, lipid profiles, uric acid, renal function and liver function in the Hualien Armed Forces General Hospital during 2014...
August 26, 2016: World Journal of Cardiology
https://www.readbyqxmd.com/read/27609631/trends-in-hospital-admissions-re-admissions-and-in-hospital-mortality-among-hiv-infected-patients-between-1993-and-2013-impact-of-hepatitis-c-co-infection
#10
Héctor Meijide, Álvaro Mena, Iria Rodríguez-Osorio, Sonia Pértega, Ángeles Castro-Iglesias, Guillermo Rodríguez-Martínez, José Pedreira, Eva Poveda
BACKGROUND: New patterns in epidemiological characteristics of people living with HIV infection (PLWH) and the introduction of Highly Active Antiretroviral Therapy (HAART) have changed the profile of hospital admissions in this population. The aim of this study was to evaluate trends in hospital admissions, re-admissions, and mortality rates in HIV patients and to analyze the role of HCV co-infection. METHODS: A retrospective cohort study conducted on all hospital admissions of HIV patients between 1993 and 2013...
September 5, 2016: Enfermedades Infecciosas y Microbiología Clínica
https://www.readbyqxmd.com/read/27469058/reduced-locomotor-activity-and-exploratory-behavior-in-cc-chemokine-receptor-4-deficient-mice
#11
Oliver Ambrée, Irene Klassen, Irmgard Förster, Volker Arolt, Stefanie Scheu, Judith Alferink
Chemokines and their receptors are key regulators of immune cell trafficking and activation. Recent findings suggest that they may also play pathophysiological roles in psychiatric diseases like depression and anxiety disorders. The CC chemokine receptor 4 (CCR4) and its two ligands, CCL17 and CCL22, are functionally involved in neuroinflammation as well as anti-infectious and autoimmune responses. However, their influence on behavior remains unknown. Here we characterized the functional role of the CCR4-CCL17 chemokine-receptor axis in the modulation of anxiety-related behavior, locomotor activity, and object exploration and recognition...
November 1, 2016: Behavioural Brain Research
https://www.readbyqxmd.com/read/27457803/serum-and-glucocorticoid-inducible-kinases-in-microglia
#12
Koichi Inoue, Eisuke Sakuma, Hiroyuki Morimoto, Hayato Asai, Yoshinori Koide, Tiandong Leng, Ikuo Wada, Zhi-Gang Xiong, Takatoshi Ueki
Microglia are derived from myelogenous cells and contribute to immunological and inflammatory responses in central nervous system. They play important roles not only in infectious diseases and inflammation after stroke, but also in psychiatric diseases such as schizophrenia. While recent studies suggest the significances of serum- and glucocorticoid-inducible kinases (SGKs) in other immune cells such as macrophages, T cells and dendritic cells, their role in microglia remains unknown. Here we, for the first time, report that SGK1 and SGK3 are expressed in multiple microglial cell lines...
September 9, 2016: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/27437286/herpes-simplex-encephalitis-an-uncommon-presentation
#13
Nidhi Kaeley, Sunil Bansal, Rohan Bhatia, Sohaib Ahmad
Herpes Simplex Virus (HSV) encephalitis is an uncommon illness, with about 2 cases per 250,000 per year. Most are caused by HSV-1, with 10% having HSV-2 as the aetiologic factor. We present a case of Herpes simplex type1encephalitis in a 70 year old male with an uncommon presentation. The patient was a known case of endogenous depression with no medical records and on no treatment for the same, reported with acute changes in mental state for the past five days. He was talking irrelevantly, had hallucinations and was unduly aggressive and violent...
May 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27429689/perception-of-the-risks-of-ebola-enterovirus-e68-and-influenza-among-emergency-department-patients
#14
Lauren K Whiteside, Rosemarie Fernandez, Justin Bammer, Graham Nichol
INTRODUCTION: Emerging infectious diseases often create concern and fear among the public. Ebola virus disease (EVD) and enterovirus (EV-68) are uncommon viral illnesses compared to influenza. The objective of this study was to determine risk for these viral diseases and then determine how public perception of influenza severity and risk of infection relate to more publicized but less common emerging infectious diseases such as EVD and EV-68 among a sample of adults seeking care at an emergency department (ED) in the United States...
July 2016: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/27418382/long-term-mortality-and-causes-of-death-associated-with-staphylococcus-aureus-bacteremia-a-matched-cohort-study
#15
N Gotland, M L Uhre, N Mejer, R Skov, A Petersen, A R Larsen, T Benfield
OBJECTIVES: Data describing long-term mortality in patients with Staphylococcus aureus bacteremia (SAB) is scarce. This study investigated risk factors, causes of death and temporal trends in long-term mortality associated with SAB. METHODS: Nationwide population-based matched cohort study. Mortality rates and ratios for 25,855 cases and 258,547 controls were analyzed by Poisson regression. Hazard ratio of death was computed by Cox proportional hazards regression analysis...
October 2016: Journal of Infection
https://www.readbyqxmd.com/read/27416536/psychiatric-comorbidities-in-opioid-dependent-patients-undergoing-a-replacement-therapy-programme-in-spain-the-proteus-study
#16
Carlos Roncero, Carmen Barral, Laia Rodríguez-Cintas, Jesús Pérez-Pazos, Nieves Martinez-Luna, Miguel Casas, Marta Torrens, Lara Grau-López
Opioid-dependent patients show a high rate of psychiatric comorbidities. The prevalence and characteristics of patients with dual diagnosis have not been well established in Spanish opioid agonist treatment (OAT) programmes. Thus, 621 opioid-dependent patients enrolled in OAT programmes were assessed, using the EuropASI questionnaire, for psychiatric comorbidities, which were detected in 67% of patients (anxiety 53%, mood disorders 48%, sleep disorders 41%, substance-related disorders 36%). In addition, compared with patients without a dual diagnosis, patients with dual pathology were significantly older, used benzodiazepines and cannabis in significantly greater percentages, and showed significantly more frequent infectious and non-infectious comorbidities, worse overall working status, a lower proportion of drivers and higher levels of severity regarding medical, employment, alcohol, legal, family and psychological issues...
September 30, 2016: Psychiatry Research
https://www.readbyqxmd.com/read/27336058/candida-albicans-exposures-sex-specificity-and-cognitive-deficits-in-schizophrenia-and-bipolar-disorder
#17
Emily G Severance, Kristin L Gressitt, Catherine R Stallings, Emily Katsafanas, Lucy A Schweinfurth, Christina L Savage, Maria B Adamos, Kevin M Sweeney, Andrea E Origoni, Sunil Khushalani, F Markus Leweke, Faith B Dickerson, Robert H Yolken
Immune aberrations in schizophrenia and bipolar disorder have led to the hypotheses that infectious agents or corresponding immune responses might contribute to psychiatric etiopathogeneses. We investigated case-control differences in exposure to the opportunistic fungal pathogen, Candida albicans, and examined associations with cognition, medication, lifestyle, and somatic conditions. We quantified C. albicans IgG antibodies in two cohorts totaling 947 individuals and evaluated odds ratios (OR) of exposure with psychiatric disorder using multivariate regressions...
2016: NPJ Schizophrenia
https://www.readbyqxmd.com/read/27303726/drug-repurposing-screening-identifies-novel-compounds-that-effectively-inhibit-toxoplasma-gondii-growth
#18
Ashley J Dittmar, Allison A Drozda, Ira J Blader
The urgent need to develop new antimicrobial therapies has spawned the development of repurposing screens in which well-studied drugs and other types of compounds are tested for potential off-label uses. As a proof-of-principle screen to identify compounds effective against Toxoplasma gondii, we screened a collection of 1,120 compounds for the ability to significantly reduce Toxoplasma replication. A total of 94 compounds blocked parasite replication with 50% inhibitory concentrations of <5 µM. A significant number of these compounds are established inhibitors of dopamine or estrogen signaling...
March 2016: MSphere
https://www.readbyqxmd.com/read/27254088/epidemiology-of-injection-drug-use-new-trends-and-prominent-issues
#19
Élise Roy, Nelson Arruda, Julie Bruneau, Didier Jutras-Aswad
After more than 30 years of research, numerous studies have shown that injection drug use is associated with a wide range of adverse health outcomes such as drug overdoses, drug-related suicidal behaviours, comorbid psychiatric disorders, bloodborne pathogens and other infectious diseases, and traumas. This review explores new trends and prominent issues associated with injection drug use. The dynamic nature of injection drug use is underlined by examining its recent trends and changing patterns in Canada and other "high-income countries...
March 2016: Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie
https://www.readbyqxmd.com/read/27246269/model-based-testing-for-space-time-interaction-using-point-processes-an-application-to-psychiatric-hospital-admissions-in-an-urban-area
#20
Sebastian Meyer, Ingeborg Warnke, Wulf Rössler, Leonhard Held
Spatio-temporal interaction is inherent to cases of infectious diseases and occurrences of earthquakes, whereas the spread of other events, such as cancer or crime, is less evident. Statistical significance tests of space-time clustering usually assess the correlation between the spatial and temporal (transformed) distances of the events. Although appealing through simplicity, these classical tests do not adjust for the underlying population nor can they account for a distance decay of interaction. We propose to use the framework of an endemic-epidemic point process model to jointly estimate a background event rate explained by seasonal and areal characteristics, as well as a superposed epidemic component representing the hypothesis of interest...
May 2016: Spatial and Spatio-temporal Epidemiology
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