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Dissociative personality disorder

J Gelauff, J Stone
The prognosis of functional (psychogenic) neurologic disorders is important in being able to help answer patients' and carers' questions, determine whether treatment is worthwhile, and to find out which factors predict outcome. We reviewed data on prognosis of functional neurologic disorders from two systematic reviews on functional motor disorders and dissociative (nonepileptic) seizures as well as additional studies on functional visual and sensory symptoms. Methodologic problems include heterogeneity in studied samples and outcome measures, diagnostic suspicion and referral bias, small size and retrospective design of available studies, possible treatments during follow-up, and literature review bias...
2017: Handbook of Clinical Neurology
Dorina Winter
Interactions between attention and processing of emotional stimuli shed light on both sensitivity to emotional stimuli as well as emotion dysregulation. Both of the latter processes have been proposed as central characteristics of altered emotion processing in those with borderline personality disorder (BPD). This review first summarizes the conflicting behavioural, psychophysiological and neuroimaging evidence for the hypothesis that emotional dysregulation should be reflected by higher distractibility through emotional stimuli in those with BPD...
2016: Borderline Personality Disorder and Emotion Dysregulation
Vedat Sar, Firdevs Alioğlu, Gamze Akyuz
Depersonalization (DEP) and derealization (DER) were examined among college students with and without borderline personality disorder (BPD) and/or dissociative disorders (DDs) by self-report and clinician assessment. The Steinberg Depersonalization and Derealization Questionnaires (SDEPQ and SDERQ), the Childhood Trauma Questionnaire, and the screening tool of the BPD section of the Structured Clinical Interview for DSM-IV (SCID-BPD) were administered to 1301 students. Those with BPD (n = 80) according to the SCID-BPD and 111 non-BPD controls were evaluated using the Structured Clinical Interview for DSM-IV Dissociative Disorders (SCID-D) by a psychiatrist blind to the diagnosis...
September 28, 2016: Journal of Trauma & Dissociation
Andrea Scalabrini, Marco Cavicchioli, Andrea Fossati, Cesare Maffei
Several authors studied dissociation within the Borderline Personality Disorder (BPD) population and postulated three dissociative subgroups. Conversely, other authors suggest how dissociation may play a central role in the development of trauma related disorders and specifically in BPD. Nevertheless, the role of dissociation in BPD seems to be controversial. Our aim is to propose a meta-analytic review of literature to evaluate the extent of dissociation in BPD compared to other psychopathological disorders to clarify its role in this specific condition...
September 28, 2016: Journal of Trauma & Dissociation
Andrew A Nicholson, Daniela Rabellino, Maria Densmore, Paul A Frewen, Christian Paret, Rosemarie Kluetsch, Christian Schmahl, Jean Théberge, Richard W J Neufeld, Margaret C McKinnon, Jim Reiss, Rakesh Jetly, Ruth A Lanius
Amygdala dysregulation has been shown to be central to the pathophysiology of posttraumatic stress disorder (PTSD) representing a critical treatment target. Here, amygdala downregulation was targeted using real-time fMRI neurofeedback (rt-fMRI-nf) in patients with PTSD, allowing us to examine further the regulation of emotional states during symptom provocation. Patients (n = 10) completed three sessions of rt-fMRI-nf with the instruction to downregulate activation in the amygdala, while viewing personalized trauma words...
September 20, 2016: Human Brain Mapping
Matthias Knefel, Ulrich S Tran, Brigitte Lueger-Schuster
BACKGROUND: Posttraumatic Stress Disorder (PTSD), Complex PTSD, and Borderline Personality Disorder (BPD) share etiological risk factors and an overlapping set of associated symptoms. Since the ICD-11 proposal for trauma-related disorders, the relationship of these disorders has to be clarified. A novel approach to psychopathology, network analysis, allows for a detailed analysis of comorbidity on symptom level. METHODS: Symptoms were assessed in adult survivors of childhood abuse (N=219) using the newly developed ICD-11 Trauma-Questionnaire and the SCID-II...
October 2016: Journal of Anxiety Disorders
Ales Grambal, Jan Prasko, Dana Kamaradova, Klara Latalova, Michaela Holubova, Zuzana Sedláčková, Radovan Hruby
INTRODUCTION: Borderline personality disorder (BPD) significantly reduces the quality of life (QoL) in mental, social, and work domains. Patients with BPD often suffer from depressive anxiety symptoms. The purpose of this cross-sectional study was to compare the QoL and demographic and clinical factors of inpatients diagnosed with BPD and comorbid anxiety spectrum disorders, and healthy controls. METHODS: Ninety-two hospitalized patients treated in the psychotherapeutic department and 40 healthy controls were included...
2016: Patient Preference and Adherence
Christian Paret, Steffen Hoesterey, Nikolaus Kleindienst, Christian Schmahl
Those with borderline personality disorder (BPD) display altered evaluations regarding reward and punishment compared to others. The processing of rewards is basal for operant conditioning. However, studies addressing operant conditioning in BPD patients are rare. In the current study, an operant conditioning task combining learning acquisition and reversal was used. BPD patients and matched healthy controls (HCs) were exposed to aversive and neutral stimuli to assess the influence of emotion on learning. Picture content, dissociation, aversive tension and symptom severity were rated...
October 30, 2016: Psychiatry Research
Paul Brown
No abstract text is available yet for this article.
August 2016: Australasian Psychiatry: Bulletin of Royal Australian and New Zealand College of Psychiatrists
Moji Aghajani, Olivier F Colins, Eduard T Klapwijk, Ilya M Veer, Henrik Andershed, Arne Popma, Nic J van der Wee, Robert R J M Vermeiren
Psychopathy is a serious psychiatric phenomenon characterized by a pathological constellation of affective (e.g., callous, unemotional), interpersonal (e.g., manipulative, egocentric), and behavioral (e.g., impulsive, irresponsible) personality traits. Though amygdala subregional defects are suggested in psychopathy, the functionality and connectivity of different amygdala subnuclei is typically disregarded in neurocircuit-level analyses of psychopathic personality. Hence, little is known of how amygdala subregional networks may contribute to psychopathy and its underlying trait assemblies in severely antisocial people...
November 2016: Human Brain Mapping
Marie Ociskova, Jan Prasko, Klara Latalova, Dana Kamaradova, Ales Grambal
BACKGROUND: Anxiety disorders are a group of various mental syndromes that have been related with generally poor treatment response. Several psychological factors may improve or hinder treatment effectiveness. Hope has a direct impact on the effectiveness of psychotherapy. Also, dissociation is a significant factor influencing treatment efficiency in this group of disorders. Development of self-stigma could decrease treatment effectiveness, as well as several temperamental and character traits...
2016: Neuropsychiatric Disease and Treatment
Carolin Steuwe, Nina Rullkötter, Verena Ertl, Michaela Berg, Frank Neuner, Thomas Beblo, Martin Driessen
BACKGROUND: This pilot study focused on the feasibility and potential effectiveness of a protocol based on Narrative Exposure Therapy (NET) that was integrated into a standard inpatient program to treat patients with comorbid Borderline Personality Disorder (BPD) and Posttraumatic Stress Disorder (PTSD). METHODS: Eleven patients (1 male, 10 female) without previous stabilization periods or the absence of intentional self-injury received NET during a ten-week inpatient program...
2016: BMC Psychiatry
Robin Bekrater-Bodmann, Boo Young Chung, Jens Foell, Dorothee Maria Gescher, Martin Bohus, Herta Flor
INTRODUCTION: Patients with borderline personality disorder (BPD) often report an unstable sense of self, which is further enhanced in dissociative states. As one consequence, BPD patients show a labile body percept, which might result in a higher degree of body plasticity. However, experimental data on body plasticity in BPD are not yet available. MATERIALS AND METHODS: The rubber hand illusion (RHI) probes the plasticity of one's body by inducing the feeling of ownership for an artificial limb...
August 2016: Comprehensive Psychiatry
Slawomira J Diener, Frauke Nees, Michèle Wessa, Gustav Wirtz, Ulrich Frommberger, Tina Penga, Michaela Ruttorf, Matthias Ruf, Christian Schmahl, Herta Flor
Exaggerated conditioned fear responses and impaired extinction along with amygdala overactivation have been observed in posttraumatic stress disorder (PTSD). These fear responses might be triggered by cues related to the trauma through higher-order conditioning, where reminders of the trauma may serve as unconditioned stimuli (US) and could maintain the fear response. We compared arousal, valence, and US expectancy ratings and BOLD brain responses using fMRI in 14 traumatized persons with PTSD and 14 without PTSD (NPTSD) and 13 matched healthy controls (HC) in a differential aversive conditioning paradigm...
October 2016: Psychophysiology
Stefanie Schelinski, Claudia Roswandowitz, Katharina von Kriegstein
People with autism spectrum disorder (ASD) have difficulties in identifying another person by face and voice. This might contribute considerably to the development of social cognition and interaction difficulties. The characteristics of the voice recognition deficit in ASD are unknown. Here, we used a comprehensive behavioral test battery to systematically investigate voice processing in high-functioning ASD (n = 16) and typically developed pair-wise matched controls (n = 16). The ASD group had particular difficulties with discriminating, learning, and recognizing unfamiliar voices, while recognizing famous voices was relatively intact...
July 12, 2016: Autism Research: Official Journal of the International Society for Autism Research
Nikolaus Kleindienst, Kathlen Priebe, Nora Görg, Anne Dyer, Regina Steil, Lisa Lyssenko, Dorina Winter, Christian Schmahl, Martin Bohus
BACKGROUND: Patients with posttraumatic stress disorder (PTSD) are prone to dissociation, which in theory should interfere with successful treatment. However, most empirical studies do not substantiate this assumption. OBJECTIVE: The primary objective was to test whether state dissociation predicts the success of an adaptation of dialectical behavior therapy designed for the treatment of patients with PTSD after childhood sexual abuse (CSA) (DBT-PTSD). We further explored whether the operationalization of dissociation as state versus trait dissociation made a difference with respect to prediction of improvement...
2016: European Journal of Psychotraumatology
Masafumi Sanefuji, Michael Craig, Valeria Parlatini, Mitul A Mehta, Declan G Murphy, Marco Catani, Leonardo Cerliani, Michel Thiebaut de Schotten
Two core symptoms characterize Attention Deficit Hyperactivity Disorder (ADHD) subtypes: inattentiveness and hyperactivity-impulsivity. While previous brain imaging research investigated ADHD as if it was a homogenous condition, its two core symptoms may originate from different brain mechanisms. We, therefore, hypothesized that the functional connectivity of cortico-striatal and attentional networks would be different between ADHD subtypes. We studied 165 children (mean age 10.93 years; age range, 7-17 year old) diagnosed as having ADHD based on their revised Conner's rating scale score and 170 typical developing individuals (mean age 11...
June 16, 2016: Cortex; a Journal Devoted to the Study of the Nervous System and Behavior
Bethany L Brand, Vedat Sar, Pam Stavropoulos, Christa Krüger, Marilyn Korzekwa, Alfonso Martínez-Taboas, Warwick Middleton
Dissociative identity disorder (DID) is a complex, posttraumatic, developmental disorder for which we now, after four decades of research, have an authoritative research base, but a number of misconceptualizations and myths about the disorder remain, compromising both patient care and research. This article examines the empirical literature pertaining to recurrently expressed beliefs regarding DID: (1) belief that DID is a fad, (2) belief that DID is primarily diagnosed in North America by DID experts who overdiagnose the disorder, (3) belief that DID is rare, (4) belief that DID is an iatrogenic, rather than trauma-based, disorder, (5) belief that DID is the same entity as borderline personality disorder, and (6) belief that DID treatment is harmful to patients...
July 2016: Harvard Review of Psychiatry
Jean-Luc Houeto, Robin Magnard, Jeffrey W Dalley, David Belin, Sebastien Carnicella
Apathy and impulsivity are two major comorbid syndromes of Parkinson's disease (PD) that may represent two extremes of a behavioral spectrum modulated by dopamine-dependent processes. PD is characterized by a progressive loss of dopaminergic neurons in the substantia nigra pars compacta to which are attributed the cardinal motor symptoms of the disorder. Dopamine replacement therapy (DRT), used widely to treat these motor symptoms, is often associated with deficits in hedonic processing and motivation, including apathy and depression, as well as impulse control disorders (ICDs)...
2016: Frontiers in Psychiatry
Carolyn M Pearson, Emily M Pisetsky, Andrea B Goldschmidt, Jason M Lavender, Stephen A Wonderlich, Ross D Crosby, Scott G Engel, James E Mitchell, Scott J Crow, Carol B Peterson
OBJECTIVE: Individuals with bulimia nervosa (BN) frequently endorse risky behaviors such as self-harm and substance use. However, no studies of BN to date have examined factors associated with engaging in individual or co-occurring risky behaviors. Given that individuals with BN often have personality psychopathology, which has been linked to symptoms and course of illness, this study sought to examine how personality may differentiate engagement in risky behaviors among BN individuals...
July 2016: International Journal of Eating Disorders
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