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Prostate cancer radium 223 start time

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https://www.readbyqxmd.com/read/27004570/chemotherapy-following-radium-223-dichloride-treatment-in-alsympca
#1
Oliver Sartor, Peter Hoskin, Robert E Coleman, Sten Nilsson, Nicholas J Vogelzang, Oana Petrenciuc, Karin Staudacher, Marcus Thuresson, Christopher Parker
BACKGROUND: Radium-223 prolongs overall survival in patients with castration-resistant prostate cancer (CRPC) and symptomatic bone metastases, regardless of prior docetaxel. Whether or not chemotherapy can be safely administered following radium-223 treatment is of clinical importance. An exploratory analysis of prospectively collected data, from the ALSYMPCA (ALpharadin in SYMptomatic Prostate CAncer) patient subgroup who received chemotherapy after radium-223 or placebo treatment, was conducted to evaluate the safety and efficacy of chemotherapy following radium-223...
July 2016: Prostate
https://www.readbyqxmd.com/read/26831188/austrian-recommendations-on-targeted-hormone-therapy-for-metastatic-castration-resistant-prostate-cancer
#2
Anton Ponholzer, Wolfgang Loidl, Jasmin Bektic, Karl Dorfinger, Stephan Hruby, Klaus Jeschke, Gero Kramer, Steffen Krause, Georg Ludvik, Mesut Remzi, Michael Roider, Franz Stoiber
In recent years, new therapeutic options have brought improvements in the treatment of metastatic, castration-resistant prostate cancer. Targeted Hormone Therapy (THT) represents a novel therapeutic component for which recent studies have shown a maximum benefit in the time between failure of androgen deprivation therapy (patient is metastatic and still pain-free) and prior to chemotherapy. Prostate cancer experts of the Austrian Society of Urology and Andrology (ÖGU), the Working Group for Urologic Oncology as part of the ÖGU, and the Professional Association of Austrian Urologists (BvU) have developed recommendations for the treatment of patients with asymptomatic or mildly symptomatic metastatic, castration-resistant prostate cancer...
February 2016: Wiener Klinische Wochenschrift
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