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https://www.readbyqxmd.com/read/27898351/a-case-report-of-small-bowel-obstruction-secondary-to-congenital-peritoneal-band-in-adult
#1
Yahmadi Abdelwahed, Rebii Saber, Ben Ismail Imen, Zenaidi Hakim, Zoghlami Ayoub
INTRODUCTION: Small bowel obstruction (SBO) is common in adult surgical procedures, mainly due to postoperative adhesions. Acute SBO in adults without history of abdominal surgery, trauma or clinical hernia is less common and has various etiologies. Congenital band is an extremely rare cause. PRESENTATION OF CASE: A 56-year-old man was admitted to our hospital with a two-day history of abdominal pain and bilious vomiting. He had no history of abdominal surgery or any other medical problems...
November 18, 2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27897243/diagnostic-performance-of-contrast-enhanced-ct-in-pyrrolizidine-alkaloids-induced-hepatic-sinusoidal-obstructive-syndrome
#2
Xuefeng Kan, Jin Ye, Xinxin Rong, Zhiwen Lu, Xin Li, Yong Wang, Ling Yang, Keshu Xu, Yuhu Song, Xiaohua Hou
Hepatic sinusoidal obstruction syndrome (HSOS) can be caused by pyrrolizidine alkaloids(PAs)-containing herbals. Since PAs exposure is obscure and clinical presentation of HSOS is unspecific, it is challenge to establish the diagnosis of PAs-induced HSOS. Gynura segetum is one of the most wide-use herbals containing PAs. The aim of our study is to describe the features of contrast-enhanced computed tomography (CT) in gynura segetum-induced HSOS, and then determine diagnostic performance of radiological signs...
November 29, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27878471/cerebrospinal-fluid-anti-epstein-barr-virus-specific-oligoclonal-igm-and-igg-bands-in-patients-with-clinically-isolated-and-guillain-barr%C3%A3-syndrome
#3
Diana Ferraro, Veronica Galli, Anna Maria Simone, Roberta Bedin, Francesca Vitetta, Elisa Merelli, Paolo Frigio Nichelli, Patrizia Sola
Epstein-Barr virus (EBV) has been implicated in multiple sclerosis (MS) pathogenesis. We aimed to assess the frequency of EBV-specific IgG and IgM oligoclonal bands (OCB) in cerebrospinal fluid (CSF) of 50 patients with clinically isolated syndrome (CIS) and in 27 controls with Guillain-Barré syndrome (GBS). Furthermore, we assessed correlations between the presence of OCB and CIS patients' CSF, MRI, and clinical variables. There was no difference in the proportion of CIS and GB patients with positivity for anti-EBV-specific IgG/IgM OCB...
November 22, 2016: Journal of Neurovirology
https://www.readbyqxmd.com/read/27849649/a-multicenter-phase-ii-study-of-gemcitabine-capecitabine-and-bevacizumab-for-locally-advanced-or-metastatic-biliary-tract-cancer
#4
Renuka V Iyer, Venkata K Pokuri, Adrienne Groman, Wen W Ma, Usha Malhotra, Dan M Iancu, Catherine Grande, Tanios B Saab
OBJECTIVES: Vascular endothelial growth factor overexpression, seen in 42% to 76% of biliary tract cancers (BTCs), correlates with poor survival. We explored the safety/efficacy and potential biomarkers for bevacizumab in combination with gemcitabine-capecitabine in advanced BTCs. PATIENTS AND METHODS: Inoperable stage III/IV BTC patients in our prospective study were given 1000 mg/m of gemcitabine (on days 1, 8), 650 mg/m of capecitabine (on days 1 to 14), and 15 mg/kg of bevacizumab (on day 1) in 21-day cycles...
November 15, 2016: American Journal of Clinical Oncology
https://www.readbyqxmd.com/read/27843969/gemcitabine-and-cisplatin-induced-posterior-reversible-encephalopathy-syndrome-a-case-report-with-review-of-literature
#5
Rohit Santosh Kabre, Krishna Marotirao Kamble
Posterior reversible encephalopathy syndrome (PRES) is a recently described, scarcely documented clinical entity. PRES is caused by various factors, the most common being hypertension, followed by nonhypertensive causes such as renal diseases and immunosuppressive therapy. Recently, some cases have been reported about the association of increased use of cytotoxic and immunosuppressive agents in cancer patients, and relevant reports have increased with advances in radiological examinations. Here, we report a case of gallbladder cancer with liver metastasis undergoing gemcitabine- and cisplatin-based chemotherapy who presented with complaints of seizures, headache, and bilateral lower limb weakness...
October 2016: Journal of Research in Pharmacy Practice
https://www.readbyqxmd.com/read/27829276/biliary-carcinomas-pathology-and-the-role-of-dna-mismatch-repair-deficiency
#6
Vitor Werneck Krauss Silva, Gokce Askan, Tanisha D Daniel, Maeve Lowery, David S Klimstra, Ghassan K Abou-Alfa, Jinru Shia
The pathology of biliary carcinomas is diverse with different gross and histological features in tumors arising in the different segments of the biliary system. Various epidemiological risk factors, varied genetic makeup, and tissue microenvironment are contributory factors. As biliary tumors have been shown to be a part of the Lynch syndrome tumor spectrum, it is plausible to speculate that DNA mismatch repair (MMR) deficiency plays a role in biliary tumors. Literature data suggest that DNA MMR deficiency indeed occurs in these tumors, albeit infrequently with the reported frequencies (weighted for sample size) of high level microsatellite instability (MSI) being 5% each for gallbladder carcinoma and carcinoma of extra-hepatic bile ducts, and 10% each for intrahepatic cholangiocarcinoma and ampullary carcinoma...
October 2016: Chinese Clinical Oncology
https://www.readbyqxmd.com/read/27816913/laser-acupuncture-treatment-improves-pain-and-functional-status-in-patients-with-subacromial-impingement-syndrome-a-randomized-double-blind-sham-controlled-study
#7
Sibel Kibar, Hatice Ecem Konak, Deniz Evcik, Saime Ay
OBJECTIVE:  The present study aims to determine the effect of laser acupuncture in patients with subacromial impingement syndrome (SAIS). DESIGN:  Randomized, double-blind, sham-controlled study. SETTING:  Physical medicine and rehabilitation outpatient clinic. SUBJECTS:  A total 73 patients with SAIS were randomly assigned into a treatment group (n = 36) and a control group (n = 37). METHODS : The treatment group received laser acupuncture, and the control group received sham laser acupuncture...
November 5, 2016: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/27808112/fish-gut-liver-immunity-during-homeostasis-or-inflammation-revealed-by-integrative-transcriptome-and-proteome-studies
#8
Nan Wu, Yu-Long Song, Bei Wang, Xiang-Yang Zhang, Xu-Jie Zhang, Ya-Li Wang, Ying-Yin Cheng, Dan-Dan Chen, Xiao-Qin Xia, Yi-Shan Lu, Yong-An Zhang
The gut-associated lymphoid tissue, connected with liver via bile and blood, constructs a local immune environment of both defense and tolerance. The gut-liver immunity has been well-studied in mammals, yet in fish remains largely unknown, even though enteritis as well as liver and gallbladder syndrome emerged as a limitation in aquaculture. In this study, we performed integrative bioinformatic analysis for both transcriptomic (gut and liver) and proteomic (intestinal mucus and bile) data, in both healthy and infected tilapias...
November 3, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27746447/so-called-acute-acalculous-cholecystitis-in-macrophage-activation-syndrome
#9
Yukimi Otsuka, Yasushi Inoue
Acute acalculous cholecystitis (AAC) is a severe disease seen in critically ill patients, including those with autoimmune diseases. We herein report the case of a 41-year-old female who developed macrophage activation syndrome (MAS) accompanied by a recurrence of Kikuchi disease. Abdominal imaging revealed marked thickening of the gallbladder wall and pericholecystic fluid, typically found in AAC. Treatment with intravenous pulse methylprednisolone induced in a significant improvement in the gallbladder wall, resulting in no need for surgical intervention...
2016: Internal Medicine
https://www.readbyqxmd.com/read/27728427/scrub-typhus-presenting-as-capillary-leak-syndrome
#10
Viswanath Mv, Chaitanya Gb
No abstract text is available yet for this article.
January 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27728117/relationship-of-prediabetes-with-acute-coronary-syndrome
#11
Chaitanya Gb
No abstract text is available yet for this article.
January 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27679736/novel-insights-into-the-polycythemia-paraganglioma-somatostatinoma-syndrome
#12
Roland Därr, Joan Nambuba, Jaydira Del Rivero, Ingo Janssen, Maria Merino, Milena Todorovic, Bela Balint, Ivana Jochmanova, Josef T Prchal, Ronald M Lechan, Arthur S Tischler, Vera Popovic, Dragana Miljic, Karen T Adams, F Ryan Prall, Alexander Ling, Meredith R Golomb, Michael Ferguson, Naris Nilubol, Clara C Chen, Emily Chew, David Taïeb, Constantine A Stratakis, Tito Fojo, Chunzhang Yang, Electron Kebebew, Zhengping Zhuang, Karel Pacak
Worldwide, the syndromes of paraganglioma (PGL), somatostatinoma (SOM) and early childhood polycythemia are described in only a few patients with somatic mutations in the hypoxia-inducible factor 2 alpha (HIF2A). This study provides detailed information about the clinical aspects and course of 7 patients with this syndrome and brings into perspective these experiences with the pertinent literature. Six females and one male presented at a median age of 28 years (range 11-46). Two were found to have HIF2A somatic mosaicism...
December 2016: Endocrine-related Cancer
https://www.readbyqxmd.com/read/27679466/spontaneous-biliary-peritonitis-with-common-bile-duct-stones-report-of-a-case
#13
Ryoga Hamura, Koichiro Haruki, Jun Tsutsumi, Sumio Takayama, Hiroaki Shiba, Katsuhiko Yanaga
Spontaneous biliary peritonitis is rare in adults. We herein report a case of spontaneous biliary peritonitis. An 84-year-old man was admitted to our hospital for abdominal pain for 5 days. He developed fever, jaundice, and abdominal rigidity. Computed tomography (CT) revealed massive ascites in the omental bursa and around the liver. The ascites obtained by diagnostic paracentesis was dark yellow-green in color, which implied bile leakage. With a diagnosis of bile peritonitis, the patient underwent emergency exploratory laparotomy...
December 2016: Surgical Case Reports
https://www.readbyqxmd.com/read/27677937/novel-treatment-options-for-bouveret-s-syndrome-a-comprehensive-review-of-61-cases-of-successful-endoscopic-treatment
#14
Jean-Marc Dumonceau, Jacques Devière
In Bouveret's syndrome, a biliary stone obstructs the duodenum. Surgical treatment is plagued by high morbidity and mortality. Therefore, endoscopic treatment has become a first-line approach. Areas covered: A literature search of Medline and Google Scholar databases was performed using the terms endoscopic treatment, non-operative treatment, Bouveret's syndrome, and gallstone ileus. Sixty-one cases of successful endoscopic treatment were found over the period 1978-2016 and are summarized herein. Therapeutic modalities used in 52 patients with complete success included mechanical lithotripsy (40% of cases), electrohydraulic lithotripsy (21% of cases), extraction of the intact stone and laser lithotripsy (15% of cases each), extracorporeal shockwave lithotripsy and duodenal stenting (4% of cases each)...
October 5, 2016: Expert Review of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/27614983/early-bilateral-gonadoblastoma-in-a-young-child-with-mosaicism-for-turner-syndrome-and-trisomy-18-with-y-chromosome
#15
Jayne M MacMahon, Maureen J O'Sullivan, Michael McDermott, Feargal Quinn, Thomas Morris, Andrew J Green, David R Betts, Susan M O'Connell
Mosaic Turner syndrome (TSM) commonly occurs in the form of 45,X/46,XX and 45,X/46,X,i(X)(q10). Mosaicism for a Y chromosome, 45,X/46,XY, has been well documented and is associated with increased risk of gonadoblastoma (GB). To date, there are only six reported cases of TSM with a trisomy 18 karyotype, and only two of these were phenotypically female with 45,X/47,XY,+18 karyotype. We present the case of a phenotypically female infant born with dysmorphic features. G-banded karyotype and interphase FISH of blood showed 45,X in 95% and 47,XY,+18 (trisomy 18) in 5% of cells analysed...
September 10, 2016: Hormone Research in Pædiatrics
https://www.readbyqxmd.com/read/27593864/prevalence-and-risk-factors-of-gallbladder-polypoid-lesions-in-a-healthy-population
#16
Yoo Shin Choi, Jae Hyuk Do, Suk Won Seo, Seung Eun Lee, Hyoung Chul Oh, Yun Joo Min, Hyun Kang
PURPOSE: To determine the prevalence of and investigate the risk factors for gallbladder (GB) polypoid lesions in a healthy population. MATERIALS AND METHODS: A total of 23827 subjects who underwent abdominal ultrasonography in conjunction with health screening examinations were retrospectively analyzed. The prevalence of risk factors for GB polypoid lesions were evaluated. In addition, risk factors according to the number of polypoid lesions and the presence of stones with polypoid lesions were investigated...
November 2016: Yonsei Medical Journal
https://www.readbyqxmd.com/read/27585469/complicated-gallstone-disease-diagnosis-and-management-of-mirizzi-syndrome
#17
Sujit S Kulkarni, Mayo Hotta, Linda Sher, Robert R Selby, Dilipkumar Parekh, James Buxbaum, Maria Stapfer
BACKGROUND: Mirizzi syndrome (MS) is characterized by an obstruction of the proximal bile duct due to extrinsic compression by either an impacted stone in the gallbladder neck or local inflammatory changes. Although this is a rare syndrome in developed countries (0.7-1.4 %), preoperative diagnosis and careful surgical management are essential to avoid bilio-vascular injuries and misdiagnosed malignancy. METHODS: The purpose of this study was to review our experience in the diagnosis and management of MS, assess the role of laparoscopy and the risk of concomitant gallbladder carcinoma...
September 1, 2016: Surgical Endoscopy
https://www.readbyqxmd.com/read/27561267/evaluation-of-the-pharmacokinetics-of-glibenclamide-tablet-given-off-label-orally-to-children-suffering-from-neonatal-syndromic-hyperglycemia
#18
Naïm Bouazza, Zoubir Djerada, Claire Gozalo, Kanetee Busiah, Jacques Beltrand, Marianne Berdugo, Saik Urien, Jean-Marc Treluyer, Michel Polak
PURPOSE: Glibenclamide (Gb) is used in type II diabetes mellitus but also in the last 10 years, off label, in patients with neonatal syndromic hyperglycemia carrying a mutation of Kir6.2 or SUR1. No studies have reported Gb pharmacokinetics in children. In this study, oral Gb pharmacokinetics was investigated in children in order to describe the concentration time courses, the influence of covariates, and the relationships between drug concentrations and efficacy. METHODS: Gb concentrations were measured in 18 children after the switch from subcutaneous insulin to oral tablets of Gb (crushed tablets for 33 % of patients)...
November 2016: European Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/27554920/successful-treatment-of-limy-bile-syndrome-extending-to-the-common-bile-duct-by-laparoscopic-cholecystectomy-and-common-bile-duct-exploration-a-case-report-and-literature-review
#19
Yuka Masuda, Yoshiaki Mizuguchi, Tomohiro Kanda, Hiroyasu Furuki, Yasuhiro Mamada, Nobuhiko Taniai, Yoshiharu Nakamura, Masato Yoshioka, Akira Matsushita, Yoichi Kawano, Tetsuya Shimizu, Eiji Uchida
Limy bile syndrome extending to the common bile duct (CBD) is a rare condition that lacks a standardized treatment. Laparoscopic cholecystectomy with laparoscopic choledocholithotomy by CBD exploration is preferred because it preserves the function of the sphincter of the Vater's papilla and allows treatment of both lesions. A 37-year-old man who was receiving entecavir for chronic hepatitis B developed right upper quadrant pain. Abdominal ultrasonography revealed a calcified shadow in the gallbladder and CBD...
August 24, 2016: Asian Journal of Endoscopic Surgery
https://www.readbyqxmd.com/read/27553925/the-porta-hepatis-microcyst-an-additional-sonographic-sign-for-the-diagnosis-of-biliary-atresia
#20
Mériam Koob, Danièle Pariente, Dalila Habes, Béatrice Ducot, Catherine Adamsbaum, Stéphanie Franchi-Abella
OBJECTIVES: To describe and evaluate an additional sonographic sign in the diagnosis of biliary atresia (BA), the microcyst of the porta hepatis, in comparison with previously described signs. METHODS: Ultrasound performed in 321 infants (mean age 55 days) with cholestasis were retrospectively analyzed. BA was surgically confirmed in 193 patients and excluded in 128. US evaluated gallbladder type (1: normal; 2: consistent with BA; 3: suspicious), triangular cord sign (TCS), microcyst and macrocyst, polysplenia syndrome, portal hypertension, and bile duct dilatation...
August 23, 2016: European Radiology
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