keyword
MENU ▼
Read by QxMD icon Read
search

Ccr

keyword
https://www.readbyqxmd.com/read/29780776/preoperative-serum-levels-of-cancer-antigen-125-and-carcinoembryonic-antigen-ratio-can-improve-differentiation-between-mucinous-ovarian-carcinoma-and-other-epithelial-ovarian-carcinomas
#1
Ji Hui Choi, Geum Seon Sohn, Doo Byung Chay, Han Byoul Cho, Jae-Hoon Kim
Objective: The main aim of this study was to evaluate cancer antigen 125 (CA125)/carcinoembryonic antigen (CEA) ratio (CCR), as a reliable marker to differentiate ovarian mucinous carcinoma from other epithelial ovarian carcinomas (EOCs), namely serous, clear cell, and endometrioid carcinomas. Methods: Female patients suffering from different kinds of EOCs whom were subjected to elective surgery at the Gangnam Severance Hospital between January 2008 and December 2016, were included in this study...
May 2018: Obstetrics & Gynecology Science
https://www.readbyqxmd.com/read/29779023/parathyroid-hormone-fibroblast-growth-factor-23-and-parameters-of-phosphate-reabsorption
#2
Kenneth R Phelps, Darius L Mason
BACKGROUND: The serum phosphorus concentration ([P]s) is the sum of EP/Ccr and TRP/Ccr, where Ccr is creatinine clearance and EP and TRP are rates of excretion and reabsorption of phosphate. In chronic kidney disease (CKD), parathyroid hormone (PTH) and fibroblast growth factor 23 (FGF23) mediate reduction of TRP/Ccr, and [PTH] and [FGF23] are linear functions of EP/Ccr. If controls and patients with CKD are considered together, TRP/Ccr is a hyperbolic function of EP/Ccr. Given these observations, we hypothesized that hyperbolas would describe relationships of phosphate reabsorption to [PTH] and [FGF23]...
May 18, 2018: American Journal of Nephrology
https://www.readbyqxmd.com/read/29755773/early-experience-with-cytoreduction-and-hyperthermic-intraperitoneal-chemotherapy-at-a-newly-developed-center-for-peritoneal-malignancy
#3
Whitney L Guerrero, Gitonga Munene, Paxton V Dickson, Dina Darby, Andrew M Davidoff, Michael G Martin, Evan S Glazer, David Shibata, Jeremiah L Deneve
Background: Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS/HIPEC) has improved outcomes for patients with peritoneal carcinomatosis (PC). We present our experience from a newly developed peritoneal surface malignancy program. Methods: An IRB approved retrospective review was performed for the first 50 patients treated with CRS/HIPEC with clinicopathologic data described. Results: Patients treated with CRS/HIPEC were Caucasian (64%), female (66%) with a median age of 53 years (range, 11-73 years)...
April 2018: Journal of Gastrointestinal Oncology
https://www.readbyqxmd.com/read/29754505/1-formula-see-text-2-formula-see-text-3-formula-see-text-4-formula-see-text-6-penta-o-galloyl-%C3%AE-d-glucose-from-galla-rhois-ameliorates-renal-tubular-injury-and-microvascular-inflammation-in-acute-kidney-injury-rats
#4
Ji Hun Park, Min Chol Kho, Hyun Cheol Oh, Youn Chul Kim, Jung Joo Yoon, Yun Jung Lee, Dae Gill Kang, Ho Sub Lee
Renal ischemia-reperfusion injury (IRI), an important cause of acute kidney injury (AKI), causes increased renal tubular injury and microvascular inflammation. 1,[Formula: see text]2,[Formula: see text]3,[Formula: see text]4,[Formula: see text]6-penta-O-galloyl-[Formula: see text]-D-glucose (PGG) from Galla rhois has anticancer, anti-oxidation and angiogenesis effects. We examined protective effects of PGG on IRI-induced acute AKI. Clamping both renal arteries for 45[Formula: see text]min induced isechemia and then reperfusion...
May 13, 2018: American Journal of Chinese Medicine
https://www.readbyqxmd.com/read/29754119/a-pilot-study-and-brief-overview-of-rehabilitation-via-virtual-environment-in-patients-suffering-from-dementia
#5
Th Fasilis, P Patrikelis, A Siatouni, A Alexoudi, A Veretzioti, L Zachou, S-St Gatzonis
Dementia is one of the increasing problems of modern societies. The immediate cure is not a possible solution, at least at the moment, but science has found a number of new ways to retard and under specific conditions to halt its development. A potential, and constantly evolving scientific field is the use of Computerized Cognitive Rehabilitation (CCR) and Virtual Environments (Vr.E). According to the existing literature, subjecting patients to various neuro-rehabilitative conditions within 3D virtual environments, allows them to obtain significant therapeutic benefits in which both transferability and durations over time are observed, in relation to the training period of the intervention...
January 2018: Psychiatrikē, Psychiatriki
https://www.readbyqxmd.com/read/29746338/oncological-and-survival-outcomes-in-watch-and-wait-patients-with-a-clinical-complete-response-after-neoadjuvant-chemoradiotherapy-for-rectal-cancer-a-systematic-review-and-pooled-analysis
#6
Mit Dattani, Richard J Heald, Ghaleb Goussous, Jack Broadhurst, Guilherme P São Julião, Angelita Habr-Gama, Rodrigo Oliva Perez, Brendan J Moran
OBJECTIVE: The aim of this study was to evaluate the oncological and survival outcomes of a Watch and Wait policy in rectal cancer after a clinical complete response (cCR) following neoadjuvant chemoradiotherapy. BACKGROUND: The detection of a cCR after neoadjuvant treatment may facilitate a nonoperative approach in selected patients. However, the long-term safety of this strategy remains to be validated. METHOD: This is a systematic review of the literature to determine the oncological outcomes in Watch and Wait patients...
May 9, 2018: Annals of Surgery
https://www.readbyqxmd.com/read/29746336/resection-of-the-primary-gastrointestinal-neuroendocrine-tumor-improves-survival-with-or-without-liver-treatment
#7
Aaron Lewis, Mustafa Raoof, Philip H G Ituarte, John Williams, Laleh Melstrom, Daneng Li, Byrne Lee, Gagandeep Singh
OBJECTIVE: The aim of this study was to determine outcomes of primary tumor resection in metastatic neuroendocrine tumors across all primary tumor sites. BACKGROUND: Primary tumor resection (PTR) may offer a survival benefit in metastatic gastrointestinal neuroendocrine tumors (GI-NETs); however, few studies have examined the effect of primary site and grade on resection and survival. METHODS: This is a retrospective study of patients with metastatic GI-NETs at presentation between 2005 and 2011 using the California Cancer Registry (CCR) dataset merged with California Office of Statewide Health Planning and Development (OSHPD) inpatient longitudinal database...
May 9, 2018: Annals of Surgery
https://www.readbyqxmd.com/read/29745479/predictors-of-one-and-two-year-mortality-in-patients-with-rectal-cancer
#8
José M Quintana, Nerea González, Santiago Lázaro, Marisa Baré, Nerea Fernandez de Larrea, Maximino Redondo, Eduardo Briones, Antonio Escobar, Cristina Sarasqueta, Susana García-Gutierrez, Ane Antón-Ladislao
AIM: Tools are needed to aid in the assessment of prognosis of patients with rectal cancer regarding the risk of medium-term mortality. The aim of this study was to develop and validate clinical prediction rules for 1- and 2-year mortality in patients undergoing surgery for rectal cancer. METHOD: A prospective cohort study of patients diagnosed with rectal cancer who underwent surgery was carried out. The main outcomes were mortality at 1 and 2 years after surgery...
May 10, 2018: Colorectal Disease: the Official Journal of the Association of Coloproctology of Great Britain and Ireland
https://www.readbyqxmd.com/read/29744672/efficacy-and-safety-of-neoadjuvant-treatment-with-bevacizumab-liposomal-doxorubicin-cyclophosphamide-and-paclitaxel-combination-in-locally-regionally-advanced-her2-negative-grade-iii-at-premenopausal-status-breast-cancer-a-phase-ii-study
#9
Ekaterini C Tampaki, Athanasios Tampakis, Constantinos E Alifieris, Dimitrios Krikelis, Anastasia Pazaiti, Michalis Kontos, Dimitrios T Trafalis
BACKGROUND: In the era of personalized therapy, targeted treatment in specific patient populations is mandated. OBJECTIVE: We evaluated the efficacy and safety of neoadjuvant treatment on locally advanced breast cancer (LABC) with a monoclonal agent against vascular endothelial growth factor (VEGF), bevacizumab plus chemotherapy combination of liposomal doxorubicin, cyclophosphamide and paclitaxel (PLAC-B). METHODS: Patients enrolled were at premenopausal status and characterized by human epidermal growth factor receptor 2 (HER2)-negative, hormone-receptor positive (estrogen receptor/progesterone receptor-positive [ER/PR+]) or triple-negative (TNBC), LABC (T > 3 cm), with high-grade ductal carcinoma...
May 9, 2018: Clinical Drug Investigation
https://www.readbyqxmd.com/read/29740597/unique-genetic-cassettes-in-a-thermoanaerobacterium-contribute-to-simultaneous-conversion-of-cellulose-and-monosugars-into-butanol
#10
Tinggang Li, Chen Zhang, Kun-Lin Yang, Jianzhong He
The demand for cellulosic biofuels is on the rise because of the anticipation for sustainable energy and less greenhouse gas emissions in the future. However, production of cellulosic biofuels, especially cellulosic butanol, has been hampered by the lack of potent microbes that are capable of converting cellulosic biomass into biofuels. We report a wild-type Thermoanaerobacterium thermosaccharolyticum strain TG57, which is capable of using microcrystalline cellulose directly to produce butanol (1.93 g/liter) as the only final product (without any acetone or ethanol produced), comparable to that of engineered microbes thus far...
March 2018: Science Advances
https://www.readbyqxmd.com/read/29734571/spirometry-and-oxidative-stress-after-rebreather-diving-in-warm-water
#11
Gerardo Bosco, Alex Rizzato, Silvia Quartesan, Enrico Camporesi, Simona Mrakic-Sposta, Sarah Moretti, Costantino Balestra, Alessandro Rubini
Introduction: Hyperbaric oxygen (HBO₂) therapy and use of enriched air can result in oxidative injury affecting the brain, lungs and eyes. HBO₂ exposure during diving can lead to a decrease in respiratory parameters. However, the possible effects of acute exposure to oxygen-enriched diving on subsequent spirometric performance and oxidative state in humans have not been recently described recently. We aim to investigate possible effects of acute (i) hyperbaric and (ii) hyperbaric hyperoxic exposure using scuba or closed-circuit rebreather (CCR) on subsequent spirometry and to assess the role of oxidative state after hyperoxic diving...
March 2018: Undersea & Hyperbaric Medicine: Journal of the Undersea and Hyperbaric Medical Society, Inc
https://www.readbyqxmd.com/read/29733805/il-17a-mcp-1-ccr-2-and-abca1-polymorphisms-in-children-with-non-alcoholic-fatty-liver-disease
#12
Ulas Emre Akbulut, Hamdi Cihan Emeksiz, Senol Citli, Hamdi Cihan Emeksiz, Hatice Ayca Ata Korkmaz, Gaye Baki
OBJECTIVE: The prevalence of non-alcoholic fatty liver disease in children has risen significantly, owing to the worldwide childhood obesity epidemic in the last two decades. Non-alcoholic fatty liver disease is closely linked to sedentary lifestyle, increased body mass index, and visceral adiposity. In addition, individual genetic variations also have a role in the development and progression of non-alcoholic fatty liver disease. The aim of this study was to investigate the gene polymorphisms of MCP-1 (-2518 A/G) (rs1024611), CCR-2 (190 G/A) (rs1799864), ABCA1 (883 G/A) (rs4149313), and IL-17A (-197 G/A) (rs2275913) in obese Turkish children with non-alcoholic fatty liver disease...
May 4, 2018: Jornal de Pediatria
https://www.readbyqxmd.com/read/29727956/green-remediation-of-contaminated-sediment-by-stabilization-solidification-with-industrial-by-products-and-co-2-utilization
#13
Lei Wang, Liang Chen, Daniel C W Tsang, Jiang-Shan Li, Tiffany L Y Yeung, Shiming Ding, Chi Sun Poon
Navigational dredging is an excavation of marine/freshwater sediment to maintain channels of sufficient depth for shipping safety. Due to historical inputs of anthropogenic contaminants, sediments are often contaminated by metals/metalloids, polycyclic aromatic hydrocarbons, polychlorinated biphenyls, and other contaminants. Its disposal can present significant environmental and financial burdens. This study developed a novel and green remediation method for contaminated sediment using stabilization/solidification with calcium-rich/low-calcium industrial by-products and CO2 utilization...
August 1, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29725826/pediatric-extraspinal-sacrococcygeal-ependymoma-ese-an-italian-aieop-experience-of-six-cases-and-literature-review
#14
Elisabetta Schiavello, Veronica Biassoni, Manila Antonelli, Piergiorgio Modena, Simone Cesaro, Paolo Pierani, Lorenza Gandola
BACKGROUND: Primary pediatric extraspinal sacrococcygeal ependymoma (ESE) is a very rare disease, poorly described in literature, whose diagnostic, therapeutic, and follow-up approach is still controversial. METHODS: We describe six cases of pediatric ESE treated at Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP) centers in Italy since 1983, with a review of the literature. RESULTS: All six patients had primary sacrococcygeal disease (two presacral and four subcutaneous) with median age of 10 years...
May 3, 2018: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/29725410/low-neutrophil-lymphocyte-ratio-correlates-with-extended-survival-in-patients-with-metastatic-breast-cancer-who-achieved-clinically-complete-response-following-multidisciplinary-therapy-a-retrospective-study
#15
Haruko Takuwa, Wakako Tsuji, Yoshihiro Yamamoto, Masayuki Shintaku, Fumiaki Yotsumoto
The prognosis of patients with metastatic or recurrent breast cancer (MBC) is improving as novel treatments are developed. The present study compared the clinical characteristics of patients with MBC with or without a complete clinical response (cCR) and identified the survival-associated factors. This was a retrospective study, which included 171 patients treated for MBC between 2011 and 2017 at the Shiga Medical Center for Adults. Neutrophil to lymphocytes ratios (NLRs) were determined in blood samples. The median follow-up period following diagnosis of MBC was 44 months (range, 0-217 months)...
May 2018: Oncology Letters
https://www.readbyqxmd.com/read/29718716/complex-chromosomal-aberrations-in-a-fetus-originating-from-oocytes-with-smooth-endoplasmic-reticulum-ser-aggregates
#16
Ioannis A Sfontouris, George T Lainas, Tryfon G Lainas, Efthimios Faros, Maria Banti, Katerina Kardara, Katerina Anagnostopoulou, Harris Kontos, George K Petsas, Efstratios M Kolibianakis
The presence of smooth endoplasmic reticulum aggregates (SERa) in the ooplasm is considered as the most severe oocyte dysmorphism due to its serious and potentially lethal outcomes in offspring. In the present case report, a couple underwent their first intracytoplasmic sperm injection (ICSI) cycle using a gonadotrophin releasing hormone (GnRH) antagonist protocol, followed by fetal ultrasound scanning and amniocentesis. SERa were observed in all oocytes retrieved. A singleton pregnancy was established. The second trimester fetal ultrasound scan revealed a female fetus with overlapping fingers in both hands, and amniocentesis was performed for the detection of chromosomal abnormalities...
May 2, 2018: Systems Biology in Reproductive Medicine
https://www.readbyqxmd.com/read/29713499/safety-data-from-the-phase-iii-japanese-achieve-trial-part-of-an-international-prospective-planned-pooled-analysis-of-six-phase-iii-trials-comparing-3-versus-6-months-of-oxaliplatin-based-adjuvant-chemotherapy-for-stage-iii-colon-cancer
#17
Masahito Kotaka, Takeharu Yamanaka, Takayuki Yoshino, Dai Manaka, Tetsuya Eto, Junichi Hasegawa, Akinori Takagane, Masato Nakamura, Takeshi Kato, Yoshinori Munemoto, Fumitaka Nakamura, Hiroyuki Bando, Hiroki Taniguchi, Makio Gamoh, Manabu Shiozawa, Shigetoyo Saji, Yoshihiko Maehara, Tsunekazu Mizushima, Atsushi Ohtsu, Masaki Mori
Background: The International Duration Evaluation of Adjuvant chemotherapy project investigated whether a shorter duration of oxaliplatin-based adjuvant chemotherapy was as effective as 6 months of identical chemotherapy for resected stage III colon cancer. As part of this project, we report safety data from the Japanese ACHIEVE study (JFMC47-1202-C3). Patients and methods: ACHIEVE was an open-label, multicentre trial randomising patients with stage III colon cancer to receive 3 m or 6 m of mFOLFOX6/CAPOX after surgery...
2018: ESMO Open
https://www.readbyqxmd.com/read/29712874/arginine-and-citrulline-catabolic-pathways-encoded-by-the-arc-gene-cluster-of-lactobacillus-brevis-atcc367
#18
Maria Majsnerowska, Elke E E Noens, Juke S Lolkema
High concentrations of L-arginine or L-citrulline in the growth medium provided the wine bacterium Lactobacillus brevis with a significant growth advantage. The arginine deiminase pathway (ADI) arc gene cluster of Lb. brevis contains three genes, arcD, arcE1 and arcE2, encoding putative L-arginine/L-ornithine exchangers. Uptake experiments with Lactococcus lactis cells expressing the genes showed that all three transported L-ornithine with affinities in the μM range. Similarly, ArcD and ArcE2 transported L-arginine, while ArcE1 transported L-citrulline, an intermediate of the ADI pathway...
April 30, 2018: Journal of Bacteriology
https://www.readbyqxmd.com/read/29710381/semantic-segmentation-of-mfish-images-using-convolutional-networks
#19
Esteban Pardo, José Mário T Morgado, Norberto Malpica
Multicolor in situ hybridization (mFISH) is a karyotyping technique used to detect major chromosomal alterations using fluorescent probes and imaging techniques. Manual interpretation of mFISH images is a time consuming step that can be automated using machine learning; in previous works, pixel or patch wise classification was employed, overlooking spatial information which can help identify chromosomes. In this work, we propose a fully convolutional semantic segmentation network for the interpretation of mFISH images, which uses both spatial and spectral information to classify each pixel in an end-to-end fashion...
April 30, 2018: Cytometry. Part A: the Journal of the International Society for Analytical Cytology
https://www.readbyqxmd.com/read/29705552/mudern-multi-category-classification-of-breast-histopathological-image-using-deep-residual-networks
#20
Ziba Gandomkar, Patrick C Brennan, Claudia Mello-Thoms
MOTIVATION: Identifying carcinoma subtype can help to select appropriate treatment options and determining the subtype of benign lesions can be beneficial to estimate the patients' risk of developing cancer in the future. Pathologists' assessment of lesion subtypes is considered as the gold standard, however, sometimes strong disagreements among pathologists for distinction among lesion subtypes have been previously reported in the literature. OBJECTIVE: To propose a framework for classifying hematoxylin-eosin stained breast digital slides either as benign or cancer, and then categorizing cancer and benign cases into four different subtypes each...
April 25, 2018: Artificial Intelligence in Medicine
keyword
keyword
76400
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"