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https://www.readbyqxmd.com/read/28598060/spontaneous-pneumothorax-in-h1n1-infection
#1
Ashutosh Chaturvedi, Arun Kumar
Spontaneous pneumothorax is a very rare entity in H1N1 infection unless it is co-existent with other respiratory conditions especially COPD. The other factors are old age, children below 5 years and patients with ILD. The mortality rate goes high with pulmonary illness complicated by H1N1 infection in smokers and in pregnant women. This is the first reported case of H1N1 infection with Spontaneous Pneumothorax in India.
May 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/28497210/genetic-characterization-of-influenza-a-h1n1-pandemic-2009-virus-isolates-from-mumbai
#2
Devanshi Gohil, Sweta Kothari, Pramod Shinde, Rhuta Meharunkar, Rajas Warke, Abhay Chowdhary, Ranjana Deshmukh
Pandemic influenza A (H1N1) 2009 virus was first detected in India in May 2009 which subsequently became endemic in many parts of the country. Influenza A viruses have the ability to evade the immune response through its ability of antigenic variations. The study aims to characterize influenza A (H1N1) pdm 09 viruses circulating in Mumbai during the pandemic and post-pandemic period. Nasopharyngeal swabs positive for influenza A (H1N1) pdm 09 viruses were inoculated on Madin-Darby canine kidney cell line for virus isolation...
May 11, 2017: Current Microbiology
https://www.readbyqxmd.com/read/28474629/epidemiological-clinical-profile-of-influenza-a-h1n1-2009-virus-infections-during-2015-epidemic-in-rajasthan
#3
Bharti Malhotra, Ruchi Singh, Pratibha Sharma, Deepa Meena, Jyoti Gupta, Aditya Atreya, B R Meena
BACKGROUND & OBJECTIVES: Pandemic influenza A (H1N1) 2009 virus emerged in 2009 and caused pandemic with high morbidity and mortality in India and worldwide. The number of H1N1-positive cases varied in different years in Rajasthan. The objective of the study was to present the epidemiological profile of pandemic influenza A (H1N1) 2009 virus cases in Rajasthan from January to March 2015. METHODS: A retrospective descriptive, record-based analysis of suspected and confirmed cases of pandemic influenza A (H1N1) 2009 virus infection in Rajasthan, India, from January to March 2015 was performed...
December 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/28474624/viruses-causing-severe-acute-respiratory-infections-sari-in-children-%C3%A2-5-years-of-age-at-a-tertiary-care-hospital-in-rajasthan-india
#4
Bharti Malhotra, M Anjaneya Swamy, P V Janardhan Reddy, M L Gupta
BACKGROUND & OBJECTIVES: Severe acute respiratory infection (SARI) is one of the leading causes of death among children worldwide. As different respiratory viruses exhibit similar symptoms, simultaneous detection of these viruses in a single reaction mixture can save time and cost. The present study was done in a tertiary care children's hospital for rapid identification of viruses causing SARI among children less than or equal to five years of age using multiplex real-time reverse transcription polymerase chain reaction (RT-PCR) kit...
December 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/28466053/analyzing-the-clinical-profile-of-swine-flu-influenza-a-h1n1-infection-in-central-india-a-retrospective-study
#5
Sameer Arbat, Mitesh Dave, Vinit Niranjane, Irfan Rahman, Ashok Arbat
Recently, India reported an increase in swine flu (influenza A H1N1) activity. There are limited studies on epidemiology of swine flu in Indian context. This study aims to analyze clinical and epidemiological profile of suspected swine flu cases in central India. 171 cases were included in a hospital based, observational, descriptive study conducted from December 2014 to April 2015. Demographics, clinical presentation and outcome of positive and negative cases were compared. Data was analyzed using STATA software...
March 2017: Virusdisease
https://www.readbyqxmd.com/read/28403799/descriptive-analysis-of-mortality-predictors-in-h1n1-influenza-in-south-indian-patients
#6
Kanav Khera, Ajit Singh, Girish Thunga, Jatin Agarwal, Shivanshu Awasthi, Jewel Maria Francis, Rama Bhat
BACKGROUND: H1N1 (hemagglutinin-H-neuroaminidase-N) influenza infection is associated with high morbidity and mortality because of associated complications and related factors. Predictors of mortality in H1N1 patients are studied with very few without seasonal/pandemic declaration. This study was carried out to describe the clinical features, complications and different risk factors that affect the outcome in the patients with confirmed H1N1influenza infection. METHODS: A retrospective study was done in Kasturba Medical College Hospital, Manipal, India by analyzing the medical records of 141 patients admitted from January, 2011 to June, 2015...
April 7, 2017: Infectious Disorders Drug Targets
https://www.readbyqxmd.com/read/28367767/influenza-a-h1n1-pdm09-outbreak-detected-in-inter-seasonal-months-during-the-surveillance-of-influenza-like-illness-in-pune-india-2012-2015
#7
Y K Gurav, M S Chadha, B V Tandale, V A Potdar, S D Pawar, P Shil, A R Deoshatwar, R Aarthy, A Bhushan
An outbreak of influenza A(H1N1)pdm09 was detected during the ongoing community-based surveillance of influenza-like illness (ILI). Among reported 119 influenza A(H1N1)pdm09 cases (59 cases in the year 2012 and 60 cases in 2015) in summer months, common clinical features were fever (100%), cough (90·7%), sore throat (85·7%), nasal discharge (48·7%), headache (55·5%), fatigue (18·5%), breathlessness (3·4%), and ear discharge (1·7%). Rise in ILI cases were negatively correlated with the seasonal factors such as relative humidity (Karl Pearson's correlation coefficient, i...
April 3, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28218156/risk-factors-for-death-during-a-resurgence-of-influenza-a-h1n1-pdm09-in-punjab-state-in-2013
#8
Tripurari Kumar, Deepak Bhatia, Pinnaka Venkata Maha Lakshmi, Kayla F Laserson, Jai Prakash Narain, Rajesh Kumar
BACKGROUND: In 2013, high mortality from influenza-A (H1N1) pdm09 (pH1N1) was observed in Punjab, India. OBJECTIVES: To describe cases and deaths of 2013 pH1N1 positives, to evaluate the high case fatality ratio and risk factors for pH1N1-associated mortality among the hospitalized cases in Punjab for 2013. METHODS: A case-control study was conducted and compared those who died from confirmed pH1N1 with those who survived in the hospital between January 1, 2013, and April 30, 2013...
January 2017: Indian Journal of Public Health
https://www.readbyqxmd.com/read/28198028/proinflammatory-chemokines-are-major-mediators-of-exuberant-immune-response-associated-with-influenza-a-h1n1-pdm09-virus-infection
#9
Maria Thomas, Reeta Subramaniam Mani, Mariamma Philip, Ranjeeta Adhikary, Sangeeta Joshi, Srigiri S Revadi, Shashidhar Buggi, Anita Desai, Ravi Vasanthapuram
In India, the case fatality ratio of the pandemic A (H1N1) pdm09 influenza was relatively higher when compared to seasonal Influenza A infection. Hypercytokinemia or "cytokine storm" has been previously implicated in the pathogenesis of other influenza viruses. The present study was undertaken to compare the cytokine profiles of A (H1N1) pdm09 influenza and seasonal H3 infection in Indian population and to correlate the findings with disease severity. Plasma levels of 18 cytokines/chemokines were measured by flow-cytometry using a bead based assay in patients infected with A (H1N1) pdm09 virus (n = 96) and Influenza A seasonal H3 virus (n = 30) categorised into mild, moderate, and severe groups along with healthy controls (n = 36)...
August 2017: Journal of Medical Virology
https://www.readbyqxmd.com/read/28144059/epidemiological-profile-of-acute-respiratory-distress-syndrome-patients-a-tertiary-care-experience
#10
Rahul Magazine, Shobitha Rao, Bharti Chogtu, Ramkumar Venkateswaran, Hameed Aboobackar Shahul, Umesh Goneppanavar
BACKGROUND: Acute respiratory distress syndrome (ARDS) is seen in critically ill patients. Its etiological spectrum in India is expected to be different from that seen in western countries due to the high prevalence of tropical infections. AIM: To study the epidemiological profile of ARDS patients. SETTING: A tertiary care hospital in Karnataka, India. MATERIALS AND METHODS: Retrospective analysis of 150 out of the 169 ARDS patients diagnosed during 2010-2012...
January 2017: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/27997573/genetic-characterization-of-circulating-2015-a-h1n1-pdm09-influenza-viruses-from-eastern-india
#11
Anupam Mukherjee, Mukti Kant Nayak, Shanta Dutta, Samiran Panda, Biswa Ranjan Satpathi, Mamta Chawla-Sarkar
In 2015, the swine derived A(H1N1)pdm09 pandemic strain outbreak became widespread throughout the different states of India. The reported cases and deaths in 2015 surpassed the previous years with more than 39000 laboratory confirmed cases and a death toll of more than 2500 people. There are relatively limited complete genetic sequences available for this virus from Asian countries. In this study, we describe the full genome analysis of influenza 2015 A(H1N1)pdm09 viruses isolated from West Bengal between January through December 2015...
2016: PloS One
https://www.readbyqxmd.com/read/27790597/knowledge-and-awareness-regarding-swine-influenza-a-h1n1-virus-infection-among-dental-professionals-in-india-a-systematic-review
#12
REVIEW
Ramandeep Singh Gambhir, Prabh Roohan Pannu, Tarun Nanda, Gagandeep Arora, Amanpreet Kaur
INTRODUCTION: Swine flu or Influenza A (H1N1) flu is the most recent of the pandemic disease that has affected the world's population. We, as health care providers should feel responsible for reducing the transmission of influenza. AIM: To conduct a systematic review of observational studies and to assess dental professionals' knowledge and awareness regarding swine flu. MATERIALS AND METHODS: Relevant cross-sectional observational studies were included in the systematic review to assess the level of knowledge and awareness regarding swine flu among dental professionals...
September 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27759342/a-study-of-outbreak-of-swine-flu-h1n1-in-north-west-zone-of-rajasthan-current-status-2015
#13
Surendra Kumar
BACKROUND: The outbreak of H1N1 virus had previously reported in India during 2009 flu pandemic. In 2015, the outbreak became widespread throughout India. The states of Gujarat and Rajasthan are severely elected. We studied an outbreak of H1N1 Virus in north-west zone of Rajasthan 2015. OBJECTIVE: To demonstrate the current epidemiological scenario of swine flu (H1N1) in north-west zone of Rajasthan with different demographic factors. METHODS: We screened total 6390 patients...
July 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27728444/clinical-profile-of-h1n1-influenza-it-s-awareness-experience-at-a-tertiary-care-centre-in-south-india
#14
Harikrishna A, Chandrashekar V, Gururaj N, Srilatha
No abstract text is available yet for this article.
January 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27380821/genetic-analysis-of-neuraminidase-gene-of-influenza-a-h1n1-pdm09-virus-circulating-in-southwest-india-from-2009-to-2012
#15
Anitha Jagadesh, Abdul Ajees Abdul Salam, Vahid Rajabali Zadeh, Govindakarnavar Arunkumar
Genetic analysis of neuraminidase gene sequences in 23 archived isolates of influenza A(H1N1)pdm09 virus, isolated during the 2009-2012 influenza seasons, was carried out to determine the genetic variability. Amino acid substitutions were observed at the rates of 0.3-0.7% per year. The catalytic site consisting of 8 functional and 11 framework residues were found conserved in 20 isolates and mutated in three (E228G, E278G, and N295T) isolates. To the best of our knowledge the three catalytic site mutants observed in our study have not been reported elsewhere to date...
February 2017: Journal of Medical Virology
https://www.readbyqxmd.com/read/27366763/the-emergence-and-consistency-of-influenza-strains-causing-influenza-like-illness-in-himachal-pradesh-india
#16
Arti Bharmoria, Vipin Behari Vaish, Ashish Chaurasia, A K Tahlan
The present study offers the status of ongoing surveillance influenza at National Influenza Surveillance Centre (NISC), Central Research Institute (CRI), Kasauli for the emergence and consistency of influenza strains for current as well as over a period of three decades in Solan, Himachal Pradesh. From 1980 to 2015, various clinical centers of Himachal reported counts of influenza-like illness (fever including cough or sore throat). During these years, the respiratory specimens of 6581 patients showing influenza-like illness were collected...
June 2016: Virusdisease
https://www.readbyqxmd.com/read/27036721/treatment-and-prevention-of-pandemic-h1n1-influenza
#17
REVIEW
Suresh Rewar, Dashrath Mirdha, Prahlad Rewar
BACKGROUND: Swine influenza is a respiratory infection common to pigs worldwide caused by type A influenza viruses, principally subtypes H1N1, H1N2, H2N1, H3N1, H3N2, and H2N3. Swine influenza viruses also can cause moderate to severe illness in humans and affect persons of all age groups. People in close contact with swine are at especially high risk. Until recently, epidemiological study of influenza was limited to resource-rich countries. The World Health Organization declared an H1N1 pandemic on June 11, 2009, after more than 70 countries reported 30,000 cases of H1N1 infection...
September 2015: Annals of Global Health
https://www.readbyqxmd.com/read/26960638/influenza-a-h1n1-pdm09-cases-in-sub-himalayan-region-2014-2015-india
#18
Pooja Sharma, Swati Gupta, Digvijay Singh, Santwana Verma, Anil Kanga
Current influenza A(H1N1)pdm09 strain severely involved many parts of the country. The study was conducted to analyze the clinicoepidemiological trend of influenza A(H1N1)pdm09 cases from October 2014 to March 2015. Samples processing was done as per the Center for Disease Control guidelines. A total of 333 specimens were processed out of which influenza A(H1N1)pdm09 constituted 24% (81) of total, 5% (18) cases were seasonal influenza A virus strains. Mean age group involved was 49 years with case fatality rate of 20%...
January 2016: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/26917878/clinico-epidemiological-profile-pandemic-influenza-a-h1n1-2009-and-seasonal-influenza-august-2009-march-2013-himachal-pradesh-india
#19
Vinod Kumar Mehta, Pooja Sharma, Ramesh Chand Guleria, Sunite A Ganju, Digvijay Singh, Anil Kanga
BACKGROUND: Novel influenza A (H1N1) virus emerged in April, 2009, spread rapidly to become pandemic by June, 2009. OBJECTIVE: To study the clinco-epidemiological profile of pH1N1and seasonal influenza (SI) from 2009 to 2013. MATERIALS AND METHODS: Retrospective, hospital-based study was done by reviewing medical records for collecting demographic and clinical profile of the study samples. RESULT: Out of 969 samples, positivity and case fatality for pH1N1 and SI was 9...
January 2016: Indian Journal of Community Medicine
https://www.readbyqxmd.com/read/26876980/emergence-of-influenza-a-h1n1-pdm09-genogroup-6b-and-drug-resistant-virus-india-january-to-may-2015
#20
Manmohan Parida, Paban Kumar Dash, Jyoti S Kumar, Gaurav Joshi, Kundan Tandel, Shashi Sharma, Ambuj Srivastava, Ankita Agarwal, Amrita Saha, Shweta Saraswat, Divyanshi Karothia, Vatsala Malviya
To investigate the aetiology of the 2015 A(H1N1)pdm09 influenza outbreak in India, 1,083 nasopharyngeal swabs from suspect patients were screened for influenza A(H1N1)pdm09 in the state of Madhya Pradesh. Of 412 positive specimens, six were further characterised by phylogenetic analysis of haemagglutinin (HA) sequences revealing that they belonged to genogroup 6B. A new mutation (E164G) was observed in HA2 of two sequences. Neuraminidase genes in two of 12 isolates from fatal cases on prior oseltamivir treatment harboured the H275Y mutation...
2016: Euro Surveillance: Bulletin Européen sur les Maladies Transmissibles, European Communicable Disease Bulletin
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