keyword
MENU ▼
Read by QxMD icon Read
search

case-cohort

keyword
https://www.readbyqxmd.com/read/28814398/plasma-lipidomic-profiles-and-cardiovascular-events-in-a-randomized-intervention-trial-with-the-mediterranean-diet
#1
Estefanía Toledo, Dong D Wang, Miguel Ruiz-Canela López, Clary B Clish, Cristina Razquin, Yan Zheng, Marta Guasch-Ferré, Adela Hruby, Dolores Corella, Enrique Gómez-Gracia, Miquel Fiol, Ramón Estruch, Emilio Ros, José Lapetra, Montserrat Fito, Fernando Aros, Luis Serra-Majem, Liming Liang, Jordi Salas-Salvadó, Frank B Hu, Miguel A Martínez-González
Background: Lipid metabolites may partially explain the inverse association between the Mediterranean diet (MedDiet) and cardiovascular disease (CVD).Objective: We evaluated the associations between 1) lipid species and the risk of CVD (myocardial infarction, stroke, or cardiovascular death); 2) a MedDiet intervention [supplemented with extra virgin olive oil (EVOO) or nuts] and 1-y changes in these molecules; and 3) 1-y changes in lipid species and subsequent CVD.Design: With the use of a case-cohort design, we profiled 202 lipid species at baseline and after 1 y of intervention in the PREDIMED (PREvención con DIeta MEDiterránea) trial in 983 participants [230 cases and a random subcohort of 790 participants (37 overlapping cases)]...
August 16, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28803571/a-national-register-based-study-of-paediatric-varicella-hospitalizations-in-denmark-2010-2016
#2
I G Helmuth, A Poulsen, K Mølbak
Varicella, usually a mild disease of childhood, can also cause complications and hospitalization. Universal varicella immunization is implemented in several countries worldwide, but not in Denmark. Taking advantage of unique national registers, we aimed to estimate the incidence of paediatric varicella hospitalizations and assess determinants for hospitalization. For this purpose, we designed a nationwide, retrospective register study of paediatric varicella hospitalizations and applied a case-cohort design and logistic regression analysis comparing hospitalized varicella patients to a sample of the entire paediatric population in Denmark...
August 14, 2017: Epidemiology and Infection
https://www.readbyqxmd.com/read/28801372/multi-variant-genetic-panel-for-genetic-risk-of-opioid-addiction
#3
Keri Donaldson, Laurence Demers, Kirk Taylor, Joe Lopez, Sherman Chang
Over 116 million people worldwide have chronic pain and prescription dependence. In the US, opioids account for the majority of overdose deaths, and in 2014, almost 2 million Americans abused or were dependent on prescription opioids. Genetic factors may play a key role in opioid prescription addiction. Herein, we describe genetic variations between opioid addicted and non-addicted populations and derive a predictive model determining risk of opioid addiction. This case cohort study compares the frequency of 16 single nucleotide polymorphisms involved in the brain reward pathways in patients with and without opioid addiction...
August 2017: Annals of Clinical and Laboratory Science
https://www.readbyqxmd.com/read/28770538/night-shift-work-and-risk-of-breast-cancer
#4
REVIEW
Johnni Hansen
PURPOSE OF REVIEW: Night work is increasingly common and a necessity in certain sectors of the modern 24-h society. The embedded exposure to light-at-night, which suppresses the nocturnal hormone melatonin with oncostatic properties and circadian disruption, i.e., misalignment between internal and external night and between cells and organs, are suggested as main mechanisms involved in carcinogenesis. In 2007, the International Agency for Research on Cancer (IARC) classified shift work that involves circadian disruption as probably carcinogenic to humans based on limited evidence from eight epidemiologic studies on breast cancer, in addition to sufficient evidence from animal experiments...
August 2, 2017: Current Environmental Health Reports
https://www.readbyqxmd.com/read/28762893/overlapping-microrna-expression-in-saliva-and-cerebrospinal-fluid-accurately-identifies-pediatric-traumatic-brain-injury
#5
Steven Daniel Hicks, Jeremiah Johnson, Molly C Carney, Harry Bramley, Robert P Olympia, Andrea C Loeffert, Neal J Thomas
Objectives To assess the accuracy and physiologic relevance of circulating microRNA (miRNA) as a biomarker of pediatric concussion, we compared changes in salivary miRNA and cerebrospinal fluid (CSF) miRNA following childhood traumatic brain injury (TBI). Study Design A case-cohort design was used to compare longitudinal miRNA concentrations in CSF of seven children with severe TBI against three controls without TBI. The miRNAs "altered" in CSF were interrogated in saliva of 60 children with mild TBI and compared with 18 age- and gender- matched controls...
August 1, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28762157/risk-markers-for-fatal-and-non-fatal-prescription-drug-overdose-a-meta-analysis
#6
REVIEW
Joanne E Brady, Rebecca Giglio, Katherine M Keyes, Charles DiMaggio, Guohua Li
BACKGROUND: Drug overdose is a public health crisis in the United States, due in part to the unintended consequences of increases in prescribing of opioid analgesics. Many clinicians evaluate risk markers for opioid-related harms when prescribing opioids for chronic pain; however, more data on predictive risk markers are needed. Risk markers are attributes (modifiable and non-modifiable) that are associated with increased probability of an outcome. This review aims to identify risk markers associated with fatal and non-fatal prescription drug overdose by synthesizing findings in the existing peer-reviewed and grey literature...
December 2017: Injury Epidemiology
https://www.readbyqxmd.com/read/28755021/a-regularized-variable-selection-procedure-in-additive-hazards-model-with-stratified-case-cohort-design
#7
Ai Ni, Jianwen Cai
Case-cohort designs are commonly used in large epidemiological studies to reduce the cost associated with covariate measurement. In many such studies the number of covariates is very large. An efficient variable selection method is needed for case-cohort studies where the covariates are only observed in a subset of the sample. Current literature on this topic has been focused on the proportional hazards model. However, in many studies the additive hazards model is preferred over the proportional hazards model either because the proportional hazards assumption is violated or the additive hazards model provides more relevent information to the research question...
July 28, 2017: Lifetime Data Analysis
https://www.readbyqxmd.com/read/28738185/mother-and-child-characteristics-at-birth-and-early-age-leukemia-a-case-cohort-population-based-study-in-brazil
#8
Rejane de Souza Reis, Neimar de Paula Silva, Marceli de Oliveira Santos, Julio Fernando Pinto Oliveira, Luiz Claudio Santos Thuler, Beatriz de Camargo, Maria S Pombo-de-Oliveira
OBJECTIVE: The population-based cancer registries (PBCR) and the Information System on Live Births in Brazil (Sistema de Informações sobre Nascidos Vivos [SINASC]) have information that enables the test for risk factors associated with leukemia at an early age. The aim of this study was to identify maternal and birth characteristics associated with early-age acute leukemia (EAL) in Brazil. METHODS: A case-cohort study was performed using secondary dataset information of PBCR and SINASC...
July 21, 2017: Jornal de Pediatria
https://www.readbyqxmd.com/read/28738015/observational-study-to-estimate-the-changes-in-the-effectiveness-of-bacillus-calmette-gu%C3%A3-rin-bcg-vaccination-with-time-since-vaccination-for-preventing-tuberculosis-in-the-uk
#9
Punam Mangtani, Patrick Nguipdop-Djomo, Ruth H Keogh, Lucy Trinder, Peter G Smith, Paul Em Fine, Jonathan Sterne, Ibrahim Abubakar, Emilia Vynnycky, John Watson, David Elliman, Marc Lipman, Laura C Rodrigues
BACKGROUND: Until recently, evidence that protection from the bacillus Calmette-Guérin (BCG) vaccination lasted beyond 10 years was limited. In the past few years, studies in Brazil and the USA (in Native Americans) have suggested that protection from BCG vaccination against tuberculosis (TB) in childhood can last for several decades. The UK's universal school-age BCG vaccination programme was stopped in 2005 and the programme of selective vaccination of high-risk (usually ethnic minority) infants was enhanced...
July 2017: Health Technology Assessment: HTA
https://www.readbyqxmd.com/read/28728064/ldl-subfractions-are-associated-with-incident-cardiovascular-disease-in-the-malm%C3%A3-prevention-project-study
#10
Dov Shiffman, Judy Z Louie, Michael P Caulfield, Peter M Nilsson, James J Devlin, Olle Melander
BACKGROUND AND AIMS: After assessing the risk for cardiovascular disease (CVD) based on traditional risk factors, decisions concerning lipid lowering therapy might remain uncertain. To investigate whether lipoprotein subfraction levels could aid these decisions, we assessed the association between lipoprotein subfractions and CVD, after adjustment for traditional risk factors including standard lipids. METHODS: Using a case-cohort design, participants were randomly drawn from the Malmö Prevention Project (MPP), a population-based prospective study of 18,240 participants, and supplemented with additional incident CVD events (5764 participants, 1784 CVD events)...
July 5, 2017: Atherosclerosis
https://www.readbyqxmd.com/read/28711626/influence-of-metabolic-risk-factors-on-risk-of-hepatocellular-carcinoma-and-liver-related-death-in-men-with-chronic-hepatitis-b-a-large-cohort-study
#11
Ming-Whei Yu, Chih-Lin Lin, Chun-Jen Liu, Shu-Han Yang, Yu-Lin Tseng, Chih-Feng Wu
BACKGROUND & AIMS: Little is known about the absolute risk of hepatocellular carcinoma (HCC) and liver-disease related death, in association with metabolic risk factors, for patients with hepatitis B virus (HBV) infection. METHODS: We collected data from 5373 male Taiwanese civil servants who visited Taiwan's Government Employees' Central Clinics and received routine free physical examinations from 1989 through 1992. We obtained information on liver-related morbidity and mortality in HBV carriers, 40-65 years old (n=1690), with different metabolic risk factors...
July 12, 2017: Gastroenterology
https://www.readbyqxmd.com/read/28710542/a-possible-dual-effect-of-cigarette-smoking-on-the-risk-of-postmenopausal-breast-cancer
#12
Piet A van den Brandt
Smoking seems modestly associated with breast cancer, but the potential dual effect of smoking (with opposing properties: carcinogenic vs anti-estrogenic) is understudied. The relationship between smoking before and after menopause and risk of postmenopausal breast cancer was investigated in the Netherlands Cohort Study (NLCS). In the NLCS, 62,573 women aged 55-69 years provided information on smoking, dietary and other lifestyle habits in 1986. Follow-up for cancer incidence until 2007 (20.3 years) consisted of record linkages with the Netherlands Cancer Registry and the Dutch Pathology Registry PALGA...
July 14, 2017: European Journal of Epidemiology
https://www.readbyqxmd.com/read/28706140/positive-helicobacter-pylori-status-is-associated-with-better-overall-survival-for-gastric-cancer-patients-evidence-from-case-cohort-studies
#13
Xuqian Fang, Kun Liu, Jialin Cai, Fangxiu Luo, Fei Yuan, Peizhan Chen
Helicobacter pylori (H. pylori) infection increases the gastric cancer risk; however, the influences of H. pylori infection status on the outcomes for gastric cancer patients have not yet clearly defined. Herein, we systematically assessed the epidemiological studies regarding the associations between the H.pylori infection status at diagnosis and the prognosis for gastric cancer patients with the meta-analysis methods. Thirty-three eligibility studies with 8,199 participants that had determined the H.pylori infection status and the outcomes for gastric cancer patients were identified through searching the PubMed and MEDLINE databases updated to March 1st, 2017...
June 28, 2017: Oncotarget
https://www.readbyqxmd.com/read/28698186/serum-insulin-glucose-indices-of-insulin-resistance-and-risk-of-lung-cancer
#14
Ilona Argirion, Stephanie J Weinstein, Satu Männistö, Demetrius Albanes, Alison M Mondul
BACKGROUND: Although insulin may increase risk of some cancers, few studies have examined fasting serum insulin and lung cancer risk. METHODS: We examined serum insulin, glucose, and indices of insulin resistance (insulin:glucose molar ratio and homeostasis model assessment of insulin resistance [HOMA-IR]) and lung cancer risk using a case-cohort study within the Alpha-Tocopherol, Beta-Carotene Cancer Prevention Studyof Finnish men. 196 cases and 395 subcohort members were included...
July 11, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28692192/aromatic-hydrocarbons-and-risk-of-skin-cancer-by-anatomical-site-in-25%C3%A2-000-male-offshore-petroleum-workers
#15
Jo Steinson Stenehjem, Trude Eid Robsahm, Magne Bråtveit, Sven Ove Samuelsen, Jorunn Kirkeleit, Tom Kristian Grimsrud
BACKGROUND: We prospectively examined skin cancer risk according to occupational exposure to aromatic hydrocarbons with adjustment for ultraviolet radiation exposure, in a cohort of 24 917 male offshore petroleum workers. METHODS: Hazard ratios (HRs) and 95% confidence intervals were estimated with Cox regression adapted to a stratified case-cohort design. RESULTS: During 13.5 years of follow-up, 112 cutaneous melanomas (CMs) and 70 non-melanoma skin cancers were identified...
August 2017: American Journal of Industrial Medicine
https://www.readbyqxmd.com/read/28692106/haemostasis-biomarkers-and-risk-of-intracerebral-haemorrhage-in-the-reasons-for-geographic-and-racial-differences-in-stroke-study
#16
Neil Zakai, Nels C Olson, Suzanne E Judd, Dawn O Kleindorfer, Brett M Kissela, George Howard, Mary Cushman
Pathologic alterations in haemostasis cause bleeding disorders, but it is unknown if variation within the normal range relates to intracerebral haemorrhage (ICH) risk. It was our objective to assess the prospective associations of haemostasis biomarkers with ICH risk. The REasons for Geographic and Racial Differences in Stroke study (REGARDS) recruited 30,239 U. S. individuals aged ≥45 years. ICH was ascertained through biannual telephone contact and review of deaths followed by medical record evaluation...
July 6, 2017: Thrombosis and Haemostasis
https://www.readbyqxmd.com/read/28686654/a-retrospective-case-cohort-study-comparing-treatment-outcomes-in-abacavir-versus-stavudine-containing-first-line-antiretroviral-treatment-regimens-in-children-3yrs-old-at-a-paediatric-programme-based-in-soweto-south-africa
#17
Haseena Cassim, Kennedy Otwombe, Erica Lazarus, Afaaf Liberty, Glenda E Gray, Oppel B W Greeff, Avy Violari
INTRODUCTION: The current World Health Organization guideline for first line antiretroviral therapy (ART) in HIV-infected children recommends the use of abacavir and lamivudine as nucleoside backbones and no longer includes stavudine. We compared treatment outcomes with abacavir (ABC) versus stavudine (d4T) in a cohort of HIV-1 infected children 6 and 12 months after antiretroviral therapy was initiated. METHODS: This was a retrospective case-cohort study, using programmatic data from children enrolled in the Paediatric Wellness Programme at the Perinatal HIV Research Unit in Soweto, South Africa between 2005 and 2013...
2017: PloS One
https://www.readbyqxmd.com/read/28684396/cardiac-stress-and-inflammatory-markers-as-predictors-of-heart-failure-in-patients-with-type-2-diabetes-the-advance-trial
#18
Toshiaki Ohkuma, Min Jun, Mark Woodward, Sophia Zoungas, Mark E Cooper, Diederick E Grobbee, Pavel Hamet, Giuseppe Mancia, Bryan Williams, Paul Welsh, Naveed Sattar, Jonathan E Shaw, Kazem Rahimi, John Chalmers
OBJECTIVE: This study examined the individual and combined effect of N-terminal pro-B-type natriuretic peptide (NT-proBNP), high-sensitivity cardiac troponin T (hs-cTnT), interleukin-6 (IL-6), and hs-CRP on the prediction of heart failure incidence or progression in patients with type 2 diabetes. RESEARCH DESIGN AND METHODS: A nested case-cohort study was conducted in 3,098 participants with type 2 diabetes in the Action in Diabetes and Vascular Disease: Preterax and Diamicron Modified Release Controlled Evaluation (ADVANCE) trial...
July 6, 2017: Diabetes Care
https://www.readbyqxmd.com/read/28664992/the-outcome-of-ulcerative-colitis-patients-undergoing-pouch-surgery-is-determined-by-pre-surgical-factors
#19
H Yanai, S Ben-Shachar, L Mlynarsky, L Godny, M Leshno, H Tulchinsky, I Dotan
BACKGROUND: Pouch surgery, a common intervention for ulcerative colitis (UC) complications, is often associated with the development of pouchitis. AIM: To identify predictors of pouch outcome in a cohort of patients with UC. METHODS: We conducted a retrospective unmatched case-cohort study in a tertiary IBD referral centre. Adult patients with UC were classified into the worst phenotype throughout follow-up: normal pouch, a form of chronic pouchitis (either chronic pouchitis or Crohn's like disease of pouch [CLDP]), or episodic recurrent acute pouchitis (RAP)...
June 30, 2017: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/28631079/development-of-pancreatic-cancer-is-predictable-well-in-advance-using-contrast-enhanced-ct-a-case-cohort-study
#20
Wataru Gonoi, Takana Yamakawa Hayashi, Hidemi Okuma, Masaaki Akahane, Yousuke Nakai, Suguru Mizuno, Ryosuke Tateishi, Hiroyuki Isayama, Kazuhiko Koike, Kuni Ohtomo
OBJECTIVES: To investigate the radiological findings prognostic for the development of pancreatic adenocarcinoma in a cohort of patients with hepatocellular carcinoma, using multiphasic computed tomography (CT). METHODS: A case-cohort study performed in a single university hospital. A database of patients who received hepatocellular carcinoma (HCC) treatment and trimonthly follow-up with four-phase dynamic CT was used (n = 1848). The cohort group was randomly extracted from the database (n = 103)...
June 19, 2017: European Radiology
keyword
keyword
76378
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"