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https://www.readbyqxmd.com/read/28940749/effect-of-laparoscopic-assisted-gastropexy-on-gastrointestinal-transit-time-in-dogs
#1
I M Balsa, W T N Culp, K J Drobatz, E G Johnson, P D Mayhew, S L Marks
BACKGROUND: Prophylactic gastropexy has been promoted as a means of preventing gastric volvulus during gastric dilatation and volvulus (GDV) syndrome. Little is known about the impact of gastropexy on gastrointestinal transit time. HYPOTHESIS: Laparoscopic-assisted gastropexy (LAG) will not alter gastrointestinal transit times when comparing gastric (GET), small and large bowel (SLBTT), and whole gut transit times (TTT) before and after surgery. ANIMALS: 10 healthy client-owned large-breed dogs...
September 20, 2017: Journal of Veterinary Internal Medicine
https://www.readbyqxmd.com/read/28940740/obesity-increases-the-risk-of-small-intestinal-bacterial-overgrowth-sibo
#2
B C Roland, D Lee, L S Miller, A Vegesna, R Yolken, E Severance, E Prandovszky, X E Zheng, G E Mullin
BACKGROUND: Small intestinal bacterial overgrowth (SIBO) has been associated with anatomical and motility-related abnormalities. Specifically, obesity has been postulated to alter small bowel motility, leading to SIBO. AIMS: (i) Assess the prevalence of SIBO in obesity; (ii) determine the relationship of obesity and SIBO, using small bowel transit time (SBTT) and pH; (iii) profile the gut microbiome in obese and non-obese patients with SIBO. METHODS: Thirty consecutive participants referred for SIBO underwent lactulose breath tests (LBTs) and wireless motility capsule (WMC) studies...
September 21, 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/28935445/-usefulness-of-small-bowel-capsule-endoscopy-in-gastrointestinal-bleeding
#3
Chloé Leandri, Benoit Bordacahar, Sophie Ribiere, Ammar Oudjit, Marie-Anne Guillaumot, Bertrand Brieau, Frédéric Prat, Vered Abitbol, Stanislas Chaussade, Romain Coriat
In France, upper gastrointestinal haemorrhages have an estimated annual incidence of 143 cases per 100,000 inhabitants. Classically, two types of digestive hemorrhage are described: acute and chronic digestive hemorrhages. Upper endoscopy is carried out in case of hematemesis or melena. It requires that the patient has been fasting for at least 6hours for solids and 3hours for liquids. The main etiologies of hemorrhagic hemorrhage of the origin are the vascular abnormalities, inflammatory or drug-induced ulcerations, intestinal tumors, Meckel's diverticulum, and Dieulafoy ulcer...
September 18, 2017: La Presse Médicale
https://www.readbyqxmd.com/read/28932274/the-impact-of-panenteric-capsule-endoscopy-on-the-management-of-crohn-s-disease
#4
REVIEW
Rami Eliakim
Crohn's disease (CD) is a chronic inflammatory disease, in most patients involving the small and large bowel. In recent years, with the use of small bowel video capsule endoscopy (SBCE), it has become clear that in 50% or more of adults with established CD there is not only distal but also proximal small bowel involvement that suggests poor prognosis. A great deal of effort has been put into early diagnosis and stratification of patients into low versus high risk, thus directing treatment from step-up, or accelerated step-up, to top-down therapies...
September 2017: Therapeutic Advances in Gastroenterology
https://www.readbyqxmd.com/read/28924590/physical-activity-during-video-capsule-endoscopy-correlates-with-shorter-bowel-transit-time
#5
Peter P Stanich, Joshua Peck, Christopher Murphy, Kyle M Porter, Marty M Meyer
BACKGROUND AND STUDY AIM:  Video capsule endoscopy (VCE) is limited by reliance on bowel motility for propulsion, and lack of physical activity has been proposed as a cause of incomplete studies. Our aim was to prospectively investigate the association between physical activity and VCE bowel transit. PATIENTS AND METHODS:  Ambulatory outpatients receiving VCE were eligible for the study. A pedometer was attached at the time of VCE ingestion and step count was recorded at the end of the procedure...
September 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28913777/diabetes-and-the-small-intestine
#6
REVIEW
Jonathan Gotfried, Stephen Priest, Ron Schey
Diabetes mellitus (DM) and its associated complications are becoming increasingly prevalent. Gastrointestinal symptoms associated with diabetes is known as diabetic enteropathy (DE) and may manifest as either diarrhea, fecal incontinence, constipation, dyspepsia, nausea, and vomiting or a combination of symptoms. The long-held belief that vagal autonomic neuropathy is the primary cause of DE has recently been challenged by newer theories of disease development. Specifically, hyperglycemia and the resulting oxidative stress on neural networks, including the nitrergic neurons and interstitial cells of Cajal (ICC), are now believed to play a central role in the development of DE...
September 15, 2017: Current Treatment Options in Gastroenterology
https://www.readbyqxmd.com/read/28872760/relating-gastric-scintigraphy-and-symptoms-to-motility-capsule-transit-and-pressure-findings-in-suspected-gastroparesis
#7
W L Hasler, K P May, L A Wilson, M Van Natta, H P Parkman, P J Pasricha, K L Koch, T L Abell, R W McCallum, L A Nguyen, W J Snape, I Sarosiek, J O Clarke, G Farrugia, J Calles-Escandon, M Grover, J Tonascia, L A Lee, L Miriel, F A Hamilton
BACKGROUND: Wireless motility capsule (WMC) findings are incompletely defined in suspected gastroparesis. We aimed to characterize regional WMC transit and contractility in relation to scintigraphy, etiology, and symptoms in patients undergoing gastric emptying testing. METHODS: A total of 209 patients with gastroparesis symptoms at NIDDK Gastroparesis Consortium centers underwent gastric scintigraphy and WMCs on separate days to measure regional transit and contractility...
September 5, 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/28871499/a-prospective-evaluation-of-ileocecal-valve-dysfunction-and-intestinal-motility-derangements-in-small-intestinal-bacterial-overgrowth
#8
Bani Chander Roland, Gerard E Mullin, Monica Passi, Xi Zheng, Ahmed Salem, Robert Yolken, Pankaj Jay Pasricha
BACKGROUND: Small intestinal bacterial overgrowth (SIBO) is an increasingly recognized clinical syndrome; however, its etiophathogenesis is poorly understood. We hypothesized that loss of gastric acid, a delayed intestinal transit, and ileocecal valve dysfunction may contribute to the genesis of this syndrome. AIMS: Our primary aim was to assess these parameters using wireless motility capsule (WMC) testing and to correlate them with the presence or absence of SIBO...
September 4, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28868494/small-bowel-obstruction-seven-years-after-video-capsule-retention
#9
Cátia Leitão, Ana Caldeira, António Banhudo
No abstract text is available yet for this article.
November 2016: GE Port J Gastroenterol
https://www.readbyqxmd.com/read/28868182/assessment-of-serum-angiogenic-factors-as-a-diagnostic-aid-for-small-bowel-angiodysplasia-in-patients-with-obscure-gastrointestinal-bleeding-and-anaemia
#10
Grainne Holleran, Mary Hussey, Sinead Smith, Deirdre McNamara
AIM: To assess the use of serum levels of angiopoietin-1 (Ang1), Ang2 and tumor necrosis factor-α (TNFα) as predictive factors for small bowel angiodysplasia (SBA). METHODS: Serum samples were collected from patients undergoing capsule endoscopy for any cause of obscure gastrointestinal bleeding (OGIB) or anaemia. Based on small bowel findings patients were divided into 3 groups: (1) SBA; (2) other bleeding causes; and (3) normal, according to diagnosis. Using ELISA technique we measured serum levels of Ang1, Ang2 and TNFα and compared mean and median levels between the groups based on small bowel diagnosis...
August 15, 2017: World Journal of Gastrointestinal Pathophysiology
https://www.readbyqxmd.com/read/28839900/small-bowel-endoluminal-imaging-capsule-and-enteroscopy
#11
Alberto Murino, Edward J Despott
Over the last 16 years, the disruptive technologies of small bowel capsule endoscopy and device-assisted enteroscopy have revolutionised endoluminal imaging and minimally invasive therapy of the small bowel. Further technological developments continue to expand their indications and use. This brief review highlights the state-of-the-art in this arena and aims to summarise the current and potential future role of these technologies in clinical practice.
April 2017: Frontline Gastroenterology
https://www.readbyqxmd.com/read/28835773/clinical-factors-related-to-false-positive-rates-of-patency-capsule-examination
#12
Tsunaki Sawada, Masanao Nakamura, Osamu Watanabe, Takeshi Yamamura, Takuya Ishikawa, Kazuhiro Furukawa, Kohei Funasaka, Eizaburo Ohno, Hiroki Kawashima, Ryoji Miyahara, Hidemi Goto, Yoshiki Hirooka
BACKGROUND: Retention is the most common complication of capsule endoscopy (CE), and is reported to occur in 0-13% of cases. To avoid retention, a PillCam patency capsule (PC) is used in patients with suspected intestinal stenosis. However, a relatively low positive predictive value of the PC examination has been reported previously. The aims of this study were to clarify the accuracy of PC examination and to evaluate clinical factors related to cases of false-positive detection. METHODS: We performed a retrospective single-center study of 282 consecutive patients referred for PC examination...
August 2017: Therapeutic Advances in Gastroenterology
https://www.readbyqxmd.com/read/28833703/nsaids-increase-the-risk-of-mucosal-injuries-but-not-of-overt-small-bowel-bleeding
#13
EDITORIAL
Gian Eugenio Tontini, Helmut Neumann
Since 2001, small bowel capsule endoscopy (SBCE) has been widely implemented into clinical practice as a minimal-invasive diagnostic approach for diagnosing small bowel diseases. Currently, SBCE is moreover recognized as the first-line procedure for the diagnostic work-up of obscure gastrointestinal bleeding (OGIB) and for a variety of SB disorders including Crohn's disease, inherited polyposis syndromes, suspected small bowel tumors or refractory celiac disease [1,2]. In addition, capsule endoscopy is used to guide the decision whether device assisted enteroscopy (i...
August 20, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/28816962/relationships-of-capsule-endoscopy-lewis-score-with-clinical-disease-activity-indices-c-reactive-protein-and-small-bowel-transit-time-in-pediatric-and-adult-patients-with-small-bowel-crohn-s-disease
#14
Chengcheng He, Jie Zhang, Zhenyu Chen, Xicheng Feng, Zibin Luo, Tianmo Wan, Aimin Li, Side Liu, Yuexin Ren
Relationships between the capsule endoscopy Lewis score (LS) and clinical disease activity indices and C-reactive protein (CRP) are controversial in adult patients with Crohn's disease (CD). Also, data on pediatric patients are relatively less. However, correlation between LS and small bowel transit time (SBTT) remains investigational. The aim of the present study was to explore the correlations between LS and clinical disease activity indices, CRP, SBTT in pediatric, and adult patients with small bowel CD...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28815031/capsule-retention-related-to-small-bowel-capsule-endoscopy-a-large-european-single-center-10-year-clinical-experience
#15
Artur Nemeth, Gabriele Wurm Johansson, Jörgen Nielsen, Henrik Thorlacius, Ervin Toth
BACKGROUND: The most concerning complication of video capsule endoscopy (VCE) is capsule retention (CR) in the gastrointestinal (GI) tract although clinical outcome and management of patients with CR are still uncertain in a large single center material. OBJECTIVES: The aim of this retrospective study was to investigate incidence, causes, risk factors, management and clinical outcomes of CR in a large single center between 2001 and 2011. RESULTS: 2401 consecutive small-bowel (SB) VCEs were performed...
August 2017: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/28771618/proton-pump-inhibitor-therapy-did-not-increase-the-prevalence-of-small-bowel-injury-a-propensity-matched-analysis
#16
Atsuo Yamada, Ryota Niikura, Koutarou Maki, Masanao Nakamura, Hirotsugu Watabe, Mitsuhiro Fujishiro, Shiro Oka, Shunji Fujimori, Atsushi Nakajima, Naoki Ohmiya, Takayuki Matsumoto, Shinji Tanaka, Kazuhiko Koike, Choitsu Sakamoto
BACKGROUND: Previous studies have reported that the suppression of acid secretion by using proton pump inhibitors (PPIs) results in dysbiosis of the small-bowel microbiota, leading to exacerbated small-bowel injuries, including erosions and ulcers. This study was designed to assess the association between PPI therapy and small-bowel lesions after adjustment for the differences in baseline characteristics between users and non-users of PPIs. METHODS: We retrospectively studied patients suspected to be suffering from small-bowel diseases, who underwent capsule endoscopy between 2010 and 2013...
2017: PloS One
https://www.readbyqxmd.com/read/28758120/corrigendum-to-safety-and-efficacy-of-small-bowel-examination-by-capsule-endoscopy-for-patients-before-liver-transplantation
#17
Seiji Kawano, Akinobu Takaki, Masaya Iwamuro, Tetsuya Yasunaka, Yoshiyasu Kono, Kou Miura, Toshihiro Inokuchi, Yoshiro Kawahara, Yuzo Umeda, Takahito Yagi, Hiroyuki Okada
[This corrects the article DOI: 10.1155/2017/8193821.].
2017: BioMed Research International
https://www.readbyqxmd.com/read/28747052/diagnostic-and-therapeutic-features-of-small-bowel-involvement-in-portal-hypertension
#18
Juan Egea Valenzuela, Tania Fernández Llamas, Ana Victoria García Marín, Fernando Alberca de Las Parras, Fernando Carballo Álvarez
Enteropathy is a lesser known complication of portal hypertension and consists of different changes in the mucosal layer of the small bowel which lead to the appearance of vascular and inflammatory lesions. It can be an important co-factor in the development of anemia in the cirrhotic population, and nowadays an easy and non-invasive diagnosis can be made thanks to capsule endoscopy. However, it is rarely considered in the management of patients with portal hypertension. Some aspects such as pathogenesis or incidence remain unclear and no specific recommendations are included in the guidelines regarding diagnosis or treatment...
July 27, 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28737951/monitoring-of-small-bowel-crohn-s-disease
#19
Uri Kopylov, Anastasios Koulaouzidis, Eyal Klang, Dan Carter, Shomron Ben-Horin, Rami Eliakim
In recent years, the therapeutic paradigm in Crohn's disease has shifted from a mere symptom-oriented approach, to aiming to healing of the underlying inflammation and prevention of long-term structural complications. Such "treat-to-target" approach may allow for a more stable disease course with less hospitalizations, lower requirement for surgery and improved quality of life. In Crohn's disease, the small bowel is affected in the majority of patients; frequently, Crohn's involves only the small bowel, which remains inaccessible to conventional ileocolonoscopic techniques...
July 24, 2017: Expert Review of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/28737439/systematic-review-and-meta-analysis-is-bowel-preparation-still-necessary-in-small-bowel-capsule-endoscopy
#20
Diana E Yung, Emanuele Rondonotti, Catherine Sykes, Marco Pennazio, John N Plevris, Anastastios Koulaouzidis
INTRODUCTION: Optimal bowel preparation for small bowel capsule endoscopy(SBCE) is controversial. This meta-analysis aimed to investigate the effects of laxatives in SBCE. METHODS: A comprehensive literature search was conducted for studies investigating the use of laxatives in SBCE. The primary outcome was diagnostic yield(DY) for SB findings; secondary outcomes SB visualization quality(SBVQ) and completion rate(CR). Pooled odds ratios(ORs) with 95% confidence intervals(CIs) and number needed to treat(NNT) were calculated...
August 1, 2017: Expert Review of Gastroenterology & Hepatology
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