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Small bowel capsule

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https://www.readbyqxmd.com/read/29767393/small-bowel-capsule-endoscopy-in-clinical-practice-has-anything-changed-over-13-years
#1
Marco Soncini, Carlo Maria Girelli, Roberto de Franchis, Emanuele Rondonotti
BACKGROUND: In Lombardia, one of the 20 Italian administrative Regions, small-bowel capsule endoscopy (SBCE) was introduced in 2001. In January 2011, the Regional Health Authorities established a reimbursement for outpatient SBCE. AIM: To prospectively record data on SBCE between 2011-2013 and compare them to similar data retrospectively collected from the same geographical area (covering the period 2001-2008) and published in 2008. METHODS: Consecutive SBCEs performed between January 2011 and December 2013 in Lombardia were prospectively collected...
May 16, 2018: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/29756020/multicenter-prospective-evaluation-of-the-express-view-reading-mode-for-small-bowel-capsule-endoscopy-studies
#2
Jean-Christophe Saurin, Philippe Jacob, Laurent Heyries, Christian Pesanti, Franck Cholet, Isaac Fassler, James Boulant, Slim Bramli, Antoin De Leusse, Gabriel Rahmi
Background:  Reducing the reading time of capsule endoscopy films is of high priority for gastroenterologists. We report a prospective multicenter evaluation of an "express view" reading mode (Intromedic capsule system). Methods:  Eighty-three patients with obscure gastrointestinal bleeding were prospectively included in 10 centers. All patients underwent small-bowel capsule endoscopy (Intromedic, Seoul, Republic of Korea). Films were read in standard mode, then a second reading was performed in express view mode at a second center...
May 2018: Endoscopy International Open
https://www.readbyqxmd.com/read/29754836/misoprostol-for-small-bowel-ulcers-in-patients-with-obscure-bleeding-taking-aspirin-and-non-steroidal-anti-inflammatory-drugs-masters-a-randomised-double-blind-placebo-controlled-phase-3-trial
#3
Ali S Taha, Caroline McCloskey, Paula McSkimming, Alex McConnachie
BACKGROUND: The incidence of obscure gastrointestinal bleeding, which originates from the small bowel and is mainly associated with the use of aspirin and non-steroidal anti-inflammatory drugs (NSAIDs), is rising. We assessed the efficacy and safety of misoprostol for the treatment of small bowel ulcers and erosions in patients taking low-dose aspirin or NSAIDs with obscure gastrointestinal bleeding. METHODS: In this randomised, double-blind, placebo-controlled, phase 3 trial, we recruited patients (aged ≥18 years) with small bowel ulcers who were taking low-dose aspirin, NSAIDs, or both for a minimum of 4 weeks, at University Hospital Crosshouse (Kilmarnock, UK)...
May 10, 2018: Lancet. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29754035/the-elusive-small-bowel-adenocarcinoma-in-the-terminal-ileum-a-case-report
#4
Joyce Lok Gee Ma, Paul Norman Strauss
INTRODUCTION: Small bowel malignancies are rare and often present with non-specific symptoms. Because of this, diagnosis of small bowel malignancies is often missed. PRESENTATION OF CASE: 71-year-old male presented with a four-week history of right iliac fossa pain and loss of weight. Laboratory tests showed a raised C-reactive protein, but all other pathology results and tumour-associated antigens were normal. Computed tomography (CT) of the abdomen demonstrated an inflammatory mass extending laterally into the pelvic wall...
April 27, 2018: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/29732361/nonsteroidal-anti-inflammatory-drugs-induced-diaphragm-disease-a-report-of-3-cases-and-literature-review
#5
Chun-Seok Yang, Ji Y Park, Hye Ryeon Choi, Daedong Kim
Multiple strictures of small bowel induced by nonsteroidal anti-inflammatory drugs (NSAIDs), were known as diaphragm disease. The purpose of these case reports is to present 3 cases of diaphragm disease of small bowel and summarize the clinical features of this disease entity. A 34-year-old man, a 63-year-old man, and a 66-year-old woman were admitted to Daegu Catholic University Medical Center because of recurrent intestinal obstructions. Two of these patients had taken heavy NSAIDs use. Capsule endoscopy was performed in all cases and the all capsules were retained by circumferential strictures of the ileum...
May 2018: Annals of Surgical Treatment and Research
https://www.readbyqxmd.com/read/29722829/fecal-calprotectin-as-a-selection-tool-for-small-bowel-capsule-endoscopy-in-suspected-crohn-s-disease
#6
Sara Monteiro, Mara Barbosa, Tiago Cúrdia Gonçalves, Pedro Boal Carvalho, Maria João Moreira, Bruno Rosa, José Cotter
Background: Small bowel capsule endoscopy (SBCE) is a firstline examination in patients with suspected Crohn's disease (CD) after negative ileocolonoscopy. Fecal calprotectin (FC) is a noninvasive marker of intestinal inflammation. The aim of this study was to evaluate the predictive value of FC in inflammatory activity detected by SBCE in patients with suspected CD. Methods: This is a retrospective study including patients who underwent SBCE for suspected CD between March 2015 and October 2016...
May 2, 2018: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29718225/clinical-use-of-patency-capsule-a-comprehensive-review-of-the-literature
#7
Ioannis V Mitselos, Konstantinos Katsanos, Epameinondas V Tsianos, Rami Eliakim, Dimitrios Christodoulou
The patency capsule is a radiopaque, dissolvable diagnostic tool, similar in shape and size to small bowel capsule endoscopes. It was developed to offer a simple, safe, efficient, and accurate evaluation of small bowel functional patency. Although unable to provide direct visual information regarding the presence and location of strictures, masses, or luminal narrowing of the small bowel, a successful patency test minimizes the risk of retention and allows the safe administration of a capsule endoscope. However, its use entails a low risk of potentially harmful adverse events, which in their majority are indolent and resolve spontaneously...
April 28, 2018: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/29707077/suspected-blood-indicator-to-identify-active-gastrointestinal-bleeding-a-prospective-validation
#8
Samuel Han, Julien Fahed, David R Cave
Background: The suspected blood indicator (SBI) function in the RAPID Reader v8.3 program was designed to quickly identify the presence of blood in video capsule endoscopy. While previous retrospective studies have shown that the SBI function was accurate in detecting the presence of active bleeding in the small bowel, its specificity and sensitivity were poor. Methods: An initial retrospective review (phase 1) compared 115 patients with active gastrointestinal bleeding seen on video capsule endoscopy (VCE) to 115 patients with no active bleeding seen on VCE to produce a highly accurate algorithm...
April 2018: Gastroenterology Research
https://www.readbyqxmd.com/read/29698967/motorized-spiral-enteroscopy-for-occult-bleeding
#9
Laura Mans, Marianna Arvanitakis, Horst Neuhaus, Jacques Devière
Small-bowel disorders remain a diagnostic and therapeutic challenge due to intestinal length. Their management was revolutionized by the emergence of deep enteroscopy. In comparison with video capsule endoscopy, deep enteroscopy allows diagnostic and therapeutic interventions. Spiral enteroscopy (Spirus Medical Endo-Ease Overtube) achieves progression by gentle push and manual clockwise rotation inducing pleating of the small bowel on the endoscope. It has the advantage of shorter examination time and more stability during withdrawal but requires two operators...
April 26, 2018: Digestive Diseases
https://www.readbyqxmd.com/read/29698945/comparison-of-small-bowel-lesions-using-capsule-endoscopy-in-ulcerative-colitis-and-crohn-s-disease-a-single-center-retrospective-analysis
#10
Kazeo Ninomiya, Takashi Hisabe, Yuki Okado, Yasumichi Takada, Rino Yamaoka, Yuho Sato, Masahiro Kishi, Noritaka Takatsu, Toshiyuki Matsui, Toshiharu Ueki, Kenshi Yao, Fumihito Hirai
BACKGROUND: Capsule endoscopy (CE) has allowed the characterization of small bowel lesions. However, small bowel lesions in ulcerative colitis (UC) have not been elucidated and no studies have compared between UC and Crohn's disease (CD). AIM: The objective of this study was to investigate the small bowel lesions in UC, and to characterize UC lesions by comparison with CD. METHODS: Subjects comprised 54 UC patients and 39 CD patients who underwent CE...
April 26, 2018: Digestion
https://www.readbyqxmd.com/read/29697457/association-of-clinical-and-inflammatory-markers-with-small-bowel-capsule-endoscopy-findings-in-crohn-s-disease
#11
Ioannis V Mitselos, Konstantinos H Katsanos, Athina Tatsioni, Alexandros Skamnelos, Rami Eliakim, Epameinondas V Tsianos, Dimitrios K Christodoulou
BACKGROUND: Mucosal healing is an established treatment endpoint in Crohn's disease (CD). Still, clinical indices and inflammatory markers are used widely in CD surveillance. AIM: The aim of this study was to investigate the diagnostic performance as well as the relationship of C-reactive protein (CRP) and Crohn's Disease Activity Index (CDAI) with small bowel capsule endoscopy's (SBCE) inflammation scoring index, the Lewis Score (LS). PATIENTS AND METHODS: CDAI, CRP, and SBCE findings of 30 CD patients with isolated small bowel disease were retrieved from our academic institution patient records and were analyzed statistically...
April 24, 2018: European Journal of Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29695395/aspiration-of-a-small-bowel-video-capsule-a-rare-complication
#12
Thomas Skouras, David Sawbridge, Alan Steel, Paul Collins
No abstract text is available yet for this article.
April 25, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29686230/nomogram-based-prediction-of-rebleeding-in-small-bowel-bleeding-patients-the-prsbb-score
#13
Genta Uchida, Yoshiki Hirooka, Masanao Nakamura, Osamu Watanabe, Takeshi Yamamura, Masanobu Matsushita, Hiroki Suhara, Takuya Ishikawa, Kazuhiro Furukawa, Kohei Funasaka, Eizaburo Ohno, Hiroki Kawashima, Ryoji Miyahara, Hidemi Goto
Small bowel capsule endoscopy (SBCE) and balloon-assisted endoscopy (BAE) have revolutionized the diagnosis and treatment of small bowel bleeding (SBB), allowing access to the small bowel and identification of specific bleeding lesions. However, some patients experience rebleeding after small bowel investigation, and there are no definitive algorithms for determining the most appropriate follow-up strategy in SBB patients. We developed and validated a nomogram that can predict rebleeding risk and be used to develop a risk-stratified follow-up strategy in SBB patients...
April 23, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29662538/the-accuracy-of-intestinal-ultrasound-compared-with-small-bowel-capsule-endoscopy-in-assessment-of-suspected-crohn-s-disease-in-patients-with-negative-ileocolonoscopy
#14
Dan Carter, Lior H Katz, Eytan Bardan, Eti Salomon, Shulamit Goldstein, Shomron Ben Horin, Uri Kopylov, Rami Eliakim
Background: Small bowel involvement in Crohn's disease (CD) is frequently proximal to the ileocecal valve and inaccessible by conventional ileocolonoscopy (IC). Small bowel capsule endoscopy (SBCE) is among the prime modalities for assessment of small bowel disease in these patients. Intestinal ultrasound (IUS) is an accurate bedside fast and low-cost diagnostic modality utilized in CD for both diagnosis and monitoring. The aim of this study was to examine the accuracy of IUS in patients with suspected CD after a negative IC, and to evaluate the correlation of IUS with SBCE, inflammatory biomarkers and other cross-sectional imaging techniques...
2018: Therapeutic Advances in Gastroenterology
https://www.readbyqxmd.com/read/29622900/unsuspected-small-bowel-crohn-s-disease-in-elderly-patients-diagnosed-by-video-capsule-endoscopy
#15
Che-Yung Chao, Carl Frederic Duchatellier, Ernest G Seidman
Background: Video capsule endoscopy (VCE) is increasingly performed among the elderly for obscure bleeding. Our aim was to report on the utility of VCE to uncover unsuspected Crohn's disease (CD) in elderly patients. Methods: Retrospective review of VCE performed in elderly patients (≥70 y) at a tertiary hospital (2010-2015). All underwent prior negative bidirectional endoscopies. CD diagnosis was based on consistent endoscopic findings, exclusion of other causes, and a Lewis endoscopic score (LS) > 790 (moderate-to-severe inflammation)...
2018: Diagnostic and Therapeutic Endoscopy
https://www.readbyqxmd.com/read/29622808/expert-consensus-document-advances-in-the-diagnosis-and-classification-of-gastric-and-intestinal-motility-disorders
#16
REVIEW
Jutta Keller, Gabrio Bassotti, John Clarke, Phil Dinning, Mark Fox, Madhusudan Grover, Per M Hellström, Meiyun Ke, Peter Layer, Carolina Malagelada, Henry P Parkman, S Mark Scott, Jan Tack, Magnus Simren, Hans Törnblom, Michael Camilleri
Disturbances of gastric, intestinal and colonic motor and sensory functions affect a large proportion of the population worldwide, impair quality of life and cause considerable health-care costs. Assessment of gastrointestinal motility in these patients can serve to establish diagnosis and to guide therapy. Major advances in diagnostic techniques during the past 5-10 years have led to this update about indications for and selection and performance of currently available tests. As symptoms have poor concordance with gastrointestinal motor dysfunction, clinical motility testing is indicated in patients in whom there is no evidence of causative mucosal or structural diseases such as inflammatory or malignant disease...
April 6, 2018: Nature Reviews. Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/29620627/small-bowel-capsule-endoscopy-indications-results-and-clinical-benefit-in-a-university-environment
#17
Juliane Flemming, Silke Cameron
Capsule endoscopy (CE) opened a new method for visualization of the small intestine. We here further explore its clinical implications.We retrospectively analyzed the clinical benefit of CE in view of medical history, diagnostics, and therapy. Our patient collective consisted of 203 patients. CE was investigated in the context of bleeding, anemia, abdominal pain, diarrhea, Crohn's disease, and suspected tumors.The study collective consisted of 118 male and 85 female patients with a mean age of 58 years (range 8-90 years)...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29616238/development-and-validation-of-an-automated-algorithm-to-evaluate-the-abundance-of-bubbles-in-small-bowel-capsule-endoscopy
#18
Olivia Pietri, Gada Rezgui, Aymeric Histace, Marine Camus, Isabelle Nion-Larmurier, Cynthia Li, Aymeric Becq, Einas Abou Ali, Olivier Romain, Ulriikka Chaput, Philippe Marteau, Christian Florent, Xavier Dray
Background and study aims : Bubbles can impair visualization of the small bowel (SB) mucosa during capsule endoscopy (CE). We aimed to develop and validate a computed algorithm that would allow evaluation of the abundance of bubbles in SB-CE still frames. Patients and methods : Two sets of 200 SB-CE normal still frames were created. Two experienced SB-CE readers analyzed both sets of images twice, in a random order. Each still frame was categorized as presenting with < 10 % or ≥ 10 % of bubbles...
April 2018: Endoscopy International Open
https://www.readbyqxmd.com/read/29610089/design-and-simulation-of-a-ring-shaped-linear-array-for-microultrasound-capsule-endoscopy
#19
Holly S Lay, Benjamin F Cox, Vipin Seetohul, Christine E M Demore, Sandy Cochran
Video capsule endoscopy (VCE) has significantly advanced visualization of the gastrointestinal tract since its introduction in the last 20 years. Work is now under way to combine VCE with microultrasound imaging. However, small maximum capsule dimensions, coupled with the electronics required to integrate ultrasound imaging capabilities, pose significant design challenges. This paper describes a simulation process for testing transducer geometries and imaging methodologies to achieve satisfactory imaging performance within the physical limitations of the capsule size and outlines many of the tradeoffs needed in the design of this new class of ultrasound capsule endoscopy (USCE) device...
April 2018: IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
https://www.readbyqxmd.com/read/29600441/efficacy-and-safety-of-the-newer-multiple-sclerosis-drugs-approved-since-2010
#20
REVIEW
Simon Faissner, Ralf Gold
Multiple sclerosis treatment faces tremendous changes as a result of the approval of new medications. The new medications have differing safety considerations and risks after long-term treatment, which are important for treating physicians to optimize and individualize multiple sclerosis care. Since the approval of the first multiple sclerosis capsule, fingolimod, the armamentarium of multiple sclerosis therapy has grown with the orally available medications dimethyl fumarate and teriflunomide. Fingolimod is mainly associated with cardiac side effects, dimethyl fumarate with bowel symptoms...
March 2018: CNS Drugs
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