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https://www.readbyqxmd.com/read/29317942/carcinoids-and-capsules-a-case-series-highlighting-the-utility-of-capsule-endoscopy-in-patients-with-small-bowel-carcinoids
#1
Michael G Noujaim, Jonathan Green, May Min, Christopher R Schlieve, Krunal Patel, Mitchell Cahan, David Cave
Background: Neuroendocine tumors (NETs) or carcinoids arise at many different sites of the gastrointestinal tract. The small intestine is the most common site for NETs. Diagnosing small bowel carcinoids remains challenging given their non-specific presentations and the overall low incidence of small bowel tumors. Video capsule endoscopy (VCE) has significanly improved our ability to detect small bowel malignancies. We explore the value of VCE in the initial workup and management of a series of small bowel carcinoid patients...
December 2017: Gastroenterology Research
https://www.readbyqxmd.com/read/29278576/electrical-stimulation-of-the-antagonist-muscle-during-cycling-exercise-interval-training-improves-oxygen-uptake-and-muscle-strength
#2
Ryuki Hashida, Yoshio Takano, Hiroo Matsuse, Mei Kudo, Masafumi Bekki, Masayuki Omoto, Takeshi Nago, Takumi Kawaguchi, Takuji Torimura, Naoto Shiba
A hybrid training system (HTS) is a resistance exercise method that combines voluntary concentric muscle contractions and electrically stimulated eccentric muscle contractions. We devised an exercise technique using HTS on cycle ergometer (HCE). The purpose of this study was to compare cardiorespiratory function and muscle strength when cycling exercise is combined with electrical stimulation over an extended period.Twenty-nine healthy young men were divided into an HCE group (n=14) and a VCE group (volitional cycle ergometer alone) (n=15)...
December 20, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29238592/predictors-and-characteristics-of-angioectasias-in-patients-with-obscure-gastrointestinal-bleeding-identified-by-video-capsule-endoscopy
#3
Simon Nennstiel, Annkathrin Machanek, Stefan von Delius, Bruno Neu, Bernhard Haller, Mohamed Abdelhafez, Roland M Schmid, Christoph Schlag
Background: In obscure gastrointestinal bleeding, angioectasias are common findings in video capsule endoscopy (VCE). Objective: The objective of this study was to identify predictors and characteristics of small bowel angioectasias. Methods: Video capsule examinations between 1 July 2001 and 31 July 2011 were retrospectively reviewed. Patients with obscure gastrointestinal bleeding were identified, and those with small bowel angioectasia were compared with patients without a definite bleeding source...
December 2017: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/29222714/domperidone-prolongs-oral-to-duodenal-transit-time-in-video-capsule-endoscopy
#4
Michael Mcfarlane, B Liu, C Nwokolo
PURPOSE: Domperidone is thought to accelerate gastric emptying via D2 receptor antagonism at the gastro-oesophageal and gastro-duodenal junctions. Listed in the BNF as a prokinetic anti-emetic, it has been used in video capsule endoscopy (VCE) to accelerate capsule delivery to the small intestine. We audited VCEs performed at UHCW from 2011, when as standard practice, domperidone was given pre-VCE, to 2012, after its discontinuation due to doubts about its effectiveness. METHODS: Thirty-one patients received oral domperidone 20 mg pre-VCE...
December 8, 2017: European Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29134964/a-randomized-trial-comparing-high-definition-colonoscopy-alone-with-high-definition-dye-spraying-and-electronic-virtual-chromoendoscopy-for-detection-of-colonic-neoplastic-lesions-during-ibd-surveillance-colonoscopy
#5
Marietta Iacucci, Gilaad G Kaplan, Remo Panaccione, Oluseyi Akinola, Brendan Cord Lethebe, Mark Lowerison, Yvette Leung, Kerri L Novak, Cynthia H Seow, Stefan Urbanski, Parham Minoo, Xianyong Gui, Subrata Ghosh
OBJECTIVES: Dye spraying chromoendoscopy (DCE) is recommended for the detection of colonic neoplastic lesions in inflammatory bowel disease (IBD). The majority of neoplastic lesions are visible endoscopically and therefore targeted biopsies are appropriate for surveillance colonoscopy. To compare three different techniques for surveillance colonoscopy to detect colonic neoplastic lesions in IBD patients: high definition (HD), (DCE), or virtual chromoendoscopy (VCE) using iSCAN image enhanced colonoscopy...
November 14, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/29118868/efficacy-of-video-capsule-endoscopy-in-the-management-of-suspected-small-bowel-bleeding-in-patients-with-continuous-flow-left-ventricular-assist-devices
#6
Thomas A Zikos, Jennifer Pan, Berkeley Limketkai, Dipanjan Banerjee, Nielsen Fernandez-Becker
Background: Continuous flow left ventricular assist device (CF-LVAD) patients have a high prevalence of gastrointestinal bleeding from the small bowel. Video capsule endoscopy (VCE) is often used for diagnosis in these patients, but efficacy has yet to be determined. In this study, we evaluated the efficacy of VCE in the management of CF-LVAD patients with suspected small bowel bleeding by comparing to a non-VCE CF-LVAD control group. Methods: We retrospectively reviewed the charts of all patients with CF-LVADs implanted at Stanford Hospital from January 2010 to October 2015...
October 2017: Gastroenterology Research
https://www.readbyqxmd.com/read/29017076/determination-of-the-phytochemical-composition-of-jingning-fang-and-the-in-vivo-pharmacokinetics-of-its-metabolites-in-rat-plasma-by-uplc-ms-ms
#7
Chunjing Yang, XingBin Yin, Xiaoxv Dong, Xin Zhang, Longtai You, Wenping Wang, Junhong Wang, Qinghe Chen, Jian Ni
Jingning fang (JNF) is an effective Traditional Chinese Medicine (TCM) which is used for the treatment of Attention Deficit Hyperactivity Disorder (ADHD). To clarify the bioactive constituents of JNF, a Thermo Q Exactive™ Plus Orbitrap™ mass spectrometer was used in this study. More than 127 chemical compounds were isolated and identified tentatively in the JNF extract, while 42 prototype constituents with 4 potential metabolites were identified tentatively in rat plasma. A method for simultaneous determination of polygalaxanthone III (PAIII), sibiricose A5 (A5), sibiricose A6 (A6), 3, 6'-disinapoyl sucrose (3,6'-DISS), tenuifoliside C (TEC), tenuifolin B (TNB), verbascoside (VCE), heterophyllin B (HEB) and schisandrin (SCH) in rat was developed and validated using polydatin (PLN) and psoralen (PSN) as internal standards...
November 1, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28924590/physical-activity-during-video-capsule-endoscopy-correlates-with-shorter-bowel-transit-time
#8
Peter P Stanich, Joshua Peck, Christopher Murphy, Kyle M Porter, Marty M Meyer
BACKGROUND AND STUDY AIM:  Video capsule endoscopy (VCE) is limited by reliance on bowel motility for propulsion, and lack of physical activity has been proposed as a cause of incomplete studies. Our aim was to prospectively investigate the association between physical activity and VCE bowel transit. PATIENTS AND METHODS:  Ambulatory outpatients receiving VCE were eligible for the study. A pedometer was attached at the time of VCE ingestion and step count was recorded at the end of the procedure...
September 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28815031/capsule-retention-related-to-small-bowel-capsule-endoscopy-a-large-european-single-center-10-year-clinical-experience
#9
Artur Nemeth, Gabriele Wurm Johansson, Jörgen Nielsen, Henrik Thorlacius, Ervin Toth
BACKGROUND: The most concerning complication of video capsule endoscopy (VCE) is capsule retention (CR) in the gastrointestinal (GI) tract although clinical outcome and management of patients with CR are still uncertain in a large single center material. OBJECTIVES: The aim of this retrospective study was to investigate incidence, causes, risk factors, management and clinical outcomes of CR in a large single center between 2001 and 2011. RESULTS: 2401 consecutive small-bowel (SB) VCEs were performed...
August 2017: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/28745776/aryepiglottic-fold-augmentation-as-treatment-for-late-onset-dysphagia-following-surgical-treatment-of-recurrent-laryngeal-neuropathy
#10
Aleksandar Vidovic, Uta Delling
OBJECTIVE: Coughing and dysphagia have been described following prosthetic laryngoplasty (LP) with or without ventriculectomy/ventriculocordectomy (VE/VCE) for the treatment of recurrent laryngeal neuropathy. All previous case descriptions include patients with acute onset of clinical signs after surgery that persisted. The authors observed a late-onset of dysphagia and coughing months to years after LP ± VE/VCE. The condition was always associated with an abnormality of the aryepiglottic fold (AEF)...
July 26, 2017: Tierärztliche Praxis. Ausgabe G, Grosstiere/Nutztiere
https://www.readbyqxmd.com/read/28695793/genetic-relationship-between-weaning-weight-and-milk-yield-in-nguni-cattle
#11
L T Nesengani, K A Nephawe, J Sebei, D Norris, A Maiwashe
A study was conducted to estimate the genetic relationship between weaning weight and milk yield in Nguni cattle. Milk yield data (n=125) were collected from 116 Nguni cows from Mara Research Station located in Limpopo Province and Loskop South Farm located in Mpumalanga Province using the weigh-suckle-weigh technique. Weaning weight data (n=19 065) were obtained from stud Nguni cattle from 146 herds distributed throughout South Africa. Estimates of (co)variance components for milk yield and weaning weight were calculated using PEST and VCE softwares...
July 11, 2017: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/28691043/incidence-of-small-bowel-neoplasia-in-lynch-syndrome-assessed-by-video-capsule-endoscopy
#12
Jasmijn F Haanstra, Abdul Al-Toma, Evelien Dekker, Steven A L W Vanhoutvin, Fokko M Nagengast, Elisabeth M Mathus-Vliegen, Monique E van Leerdam, Wouter H de Vos Tot Nederveen Cappel, Roeland A Veenendaal, Annemieke Cats, Silvia Sanduleanu, Hans F A Vasen, Jan H Kleibeuker, Jan J Koornstra
BACKGROUND AND STUDY AIMS : Lynch syndrome (LS) patients have an increased risk of small bowel cancer. The question is whether surveillance will lead to early detection of (pre)malignant lesions. We recently reported on prevalence of small bowel neoplasia (SBN) in LS patients as assessed by video capsule endoscopy (VCE). The aim of this prospective study was to determine the incidence of SBN. PATIENTS AND METHODS : Asymptomatic LS patients who underwent a VCE were invited to undergo a second VCE procedure 2 years later...
July 2017: Endoscopy International Open
https://www.readbyqxmd.com/read/28671642/acoustic-sensing-and-ultrasonic-drug-delivery-in-multimodal-theranostic-capsule-endoscopy
#13
Fraser R Stewart, Yongqiang Qiu, Holly S Lay, Ian P Newton, Benjamin F Cox, Mohammed A Al-Rawhani, James Beeley, Yangminghao Liu, Zhihong Huang, David R S Cumming, Inke Näthke, Sandy Cochran
Video capsule endoscopy (VCE) is now a clinically accepted diagnostic modality in which miniaturized technology, an on-board power supply and wireless telemetry stand as technological foundations for other capsule endoscopy (CE) devices. However, VCE does not provide therapeutic functionality, and research towards therapeutic CE (TCE) has been limited. In this paper, a route towards viable TCE is proposed, based on multiple CE devices including important acoustic sensing and drug delivery components. In this approach, an initial multimodal diagnostic device with high-frequency quantitative microultrasound that complements video imaging allows surface and subsurface visualization and computer-assisted diagnosis...
July 3, 2017: Sensors
https://www.readbyqxmd.com/read/28670889/heuristic-classifier-for-observe-accuracy-of-cancer-polyp-using-video-capsule-endoscopy
#14
Geetha K, Rajan C
Methods: Colonoscopy is a technique for examine colon cancer, polyps. In endoscopy, video capsule is universally used mechanism for finding gastrointestinal stages. But both the mechanisms are used to find the colon cancer or colorectal polyp. The Automatic Polyp Detection sub-challenge conducted as part of the Endoscopic Vision Challenge (http://endovis.grand-challenge.org). Method: Colonoscopy may be primary way of improve the ability of colon cancer detection especially flat lesions. Which otherwise may be difficult to detect...
June 25, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28649001/a-european-randomised-controlled-trial-of-the-addition-of-etoposide-to-standard-vincristine-and-carboplatin-induction-as-part-of-an-18-month-treatment-programme-for-childhood-%C3%A2-16%C3%A2-years-low-grade-glioma%C3%A2-a-final-report
#15
RANDOMIZED CONTROLLED TRIAL
Astrid K Gnekow, David A Walker, Daniela Kandels, Susan Picton, Giorgio Perilongo, Jacques Grill, Tore Stokland, Per Eric Sandstrom, Monika Warmuth-Metz, Torsten Pietsch, Felice Giangaspero, René Schmidt, Andreas Faldum, Denise Kilmartin, Angela De Paoli, Gian Luca De Salvo
BACKGROUND: The use of chemotherapy to manage newly diagnosed low grade glioma (LGG) was first introduced in the 1980s. One randomised trial has studied two- versus four-drug regimens with a duration of 12 months of treatment after resection. METHODS: Within the European comprehensive treatment strategy for childhood LGG, the International Society of Paediatric Oncology-Low Grade Glioma (SIOP LGG) Committee launched a randomised trial involving 118 institutions and 11 countries to investigate the addition of etoposide (100 mg/m(2), days 1, 2 & 3) to a four-course induction of vincristine (1...
August 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28629608/laparotomy-and-intraoperative-enteroscopy-for-obscure-gastrointestinal-bleeding-before-and-after-the-era-of-video-capsule-endoscopy-and-deep-enteroscopy-a-tertiary-center-experience
#16
Wuttiporn Manatsathit, Usah Khrucharoen, Dennis M Jensen, O Joe Hines, Thomas Kovacs, Gordon Ohning, Rome Jutabha, Kevin Ghassemi, Gareth S Dulai, Gustavo Machicado
BACKGROUND: To evaluate roles of intraoperative endoscopy (IOE) in management of severe obscure GI bleeding (OGIB) before vs. after introduction of video capsule endoscopy (VCE) and deep enteroscopy (DE). METHODS: We retrospectively reviewed prospectively collected data of patients undergoing IOE for severe OGIB in a tertiary referral center. RESULTS: 52 patients had laparotomy/IOE for OGIB, 11 pre and 41 post VCE/DE eras. In the pre VCE/DE era, 36...
June 16, 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/28611528/preoperative-detection-and-localization-of-small-bowel-hemangioma-two-case-reports
#17
Nobuhisa Takase, Keisuke Fukui, Takafumi Tani, Tohru Nishimura, Tomohiro Tanaka, Naoki Harada, Kimihiko Ueno, Manabu Takamatsu, Akihiko Nishizawa, Akiharu Okamura, Kunihiko Kaneda
Among the various diagnostic modalities for small bowel hemangioma, video capsule endoscopy (VCE) and double-balloon enteroscopy (DBE) can be recommended as part of the work-up in patients with obscure gastrointestinal bleeding (OGIB). DBE is superior to VCE in the accuracy of diagnosis and therapeutic potential, while in most cases total enteroscopy cannot be achieved through only the antegrade or retrograde DBE procedures. As treatment for small bowel bleeding, especially spout bleeding, localization of the lesion for the decision of DBE insertion facilitates early treatment, such as endoscopic hemostatic clipping, allowing patients to avoid useless transfusion and the worsening of their disease into life-threatening status...
May 28, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28567381/ultrasound-capsule-endoscopy-sounding-out-the-future
#18
Benjamin F Cox, Fraser Stewart, Holly Lay, Gerard Cummins, Ian P Newton, Marc P Y Desmulliez, Robert J C Steele, Inke Näthke, Sandy Cochran
Video capsule endoscopy (VCE) has been of immense benefit in the diagnosis and management of gastrointestinal (GI) disorders since its introduction in 2001. However, it suffers from a number of well recognized deficiencies. Amongst these is the limited capability of white light imaging, which is restricted to analysis of the mucosal surface. Current capsule endoscopes are dependent on visual manifestation of disease and limited in regards to transmural imaging and detection of deeper pathology. Ultrasound capsule endoscopy (USCE) has the potential to overcome surface only imaging and provide transmural scans of the GI tract...
May 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/28567379/colonic-obstruction-caused-by-video-capsule-entrapment-in-a-metal-stent
#19
Ervin Toth, Lars Marthinsen, Maria Bergström, Per-Ola Park, Peter Månsson, Artur Nemeth, Gabriele Wurm Johansson, Henrik Thorlacius
Video capsule endoscopy (VCE) has become the method of choice for visualizing the small bowel mucosa and is generally considered to be a safe method. Although uncommon, the most feared complication of VCE is capsule retention that can potentially lead to life-threatening bowel obstruction. Herein, we present for the first time a case of capsule retention in a colonic stent. The patient had known Crohn's disease with colonic involvement and underwent an uneventful but incomplete small bowel VCE for assessment of disease activity and extension for optimizing medical treatment...
May 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/28567377/coeliac-disease-and-the-videocapsule-what-have-we-learned-till-now
#20
REVIEW
Edward J Ciaccio, Suzanne K Lewis, Govind Bhagat, Peter H Green
Celiac disease is diagnosed in part by finding areas of pathology in the small bowel (SB) mucosa. This can often be difficult because the pathologic alterations, including atrophy of the small intestinal villi, can often be sparse and subtle. Some of the quantitative methods for detecting and measuring the presence of villous atrophy from videocapsule endoscopy (VCE) images are presented and discussed. These methods consist of static features of measurement including texture, gray level, and presence and abundance of fissures contained within each acquired image...
May 2017: Annals of Translational Medicine
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