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https://www.readbyqxmd.com/read/29772945/the-efficiency-of-the-uterocervical-angle-in-the-prediction-of-second-trimester-pregnancy-terminations-in-multiparous-women
#1
Berna Aslan Cetin, Begum Aydogan Mathyk, Nadiye Koroglu, Gozde Demirezen, Gokce Turan, Gokhan Demirayak, Gokhan Yildirim
AIM: To show how uterocervical angles are used for the prediction of second-trimester pregnancy terminations in multiparous women. MATERIAL AND METHODS: A total of 148 multiparous singleton women in their second trimesters were enrolled in this prospective study. The intracervical Foley catheter was used for the induction of delivery. The cervical length (CL) and the uterocervical angle (UCA) were measured before the beginning of induction. The study population was subdivided into four groups; successful and failed terminations at the end of 24 and 48 h time frames...
May 17, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29759671/yield-and-pitfalls-of-ajmaline-testing-in-the-evaluation-of-unexplained-cardiac-arrest-and-sudden-unexplained-death-single-center-experience-with-482-families
#2
Rafik Tadros, Eline A Nannenberg, Krystien V Lieve, Doris Škorić-Milosavljević, Najim Lahrouchi, Ronald H Lekanne Deprez, Jeroen Vendrik, Yolan J Reckman, Pieter G Postema, Ahmad S Amin, Connie R Bezzina, Arthur A M Wilde, Hanno L Tan
OBJECTIVES: This study evaluated the yield of ajmaline testing and assessed the occurrence of confounding responses in a large cohort of families with unexplained cardiac arrest (UCA) or sudden unexplained death (SUD). BACKGROUND: Ajmaline testing to diagnose Brugada syndrome (BrS) is routinely used in the evaluation of SUD and UCA, but its yield, limitations, and appropriate dosing have not been studied in a large cohort. METHODS: We assessed ajmaline test response and genetic testing results in 637 individuals from 482 families who underwent ajmaline testing for SUD or UCA...
December 11, 2017: JACC. Clinical Electrophysiology
https://www.readbyqxmd.com/read/29734713/mixed-incoherent-far-field-and-near-field-source-localization-under-uniform-circular-array
#3
Xiaolong Su, Zhen Liu, Xin Chen, Xiang Li
A high-accuracy algorithm is presented for the localization of mixed incoherent near-field and far-field narrow-band sources under uniform circular array (UCA). Herein, considering that it is difficult to classify the mixed sources, we first decouple mixed sources’ angles and ranges by calculating centro-symmetric sensors’ phase differences. Then, as the phase differences including only sources’ angles can be transformed as indefinite equations, each source’s azimuth angle and elevation angle are obtained by performing the least squares method...
May 4, 2018: Sensors
https://www.readbyqxmd.com/read/29690571/nonlinear-blind-compensation-for-array-signal-processing-application
#4
Jialu Huang, Hong Ma, Jiang Jin, Hua Zhang
Recently, nonlinear blind compensation technique has attracted growing attention in array signal processing application. However, due to the nonlinear distortion stemming from array receiver which consists of multi-channel radio frequency (RF) front-ends, it is too difficult to estimate the parameters of array signal accurately. A novel nonlinear blind compensation algorithm aims at the nonlinearity mitigation of array receiver and its spurious-free dynamic range (SFDR) improvement, which will be more precise to estimate the parameters of target signals such as their two-dimensional directions of arrival (2-D DOAs)...
April 22, 2018: Sensors
https://www.readbyqxmd.com/read/29681613/lipid-rich-variant-of-urothelial-carcinoma-presenting-as-the-dominant-morphology-in-a-recurrent-tumor-after-local-therapy
#5
Archi Patel, Rowena E Velilla, Muhammad Salah Shurbaji
BACKGROUND The lipid-rich variant is a rare and aggressive type of urothelial carcinoma (UCa), with less than 40 cases reported in the literature. This variant usually presents as an advanced-stage primary tumor. CASE REPORT We report the case of a 61-year-old man with previous history of T1 high-grade conventional urothelial carcinoma treated with local therapy. The patient later presented with a new 6.5-cm exophytic bladder mass. Histopathological examination revealed a T2 urothelial carcinoma of the lipid-rich variant...
April 23, 2018: American Journal of Case Reports
https://www.readbyqxmd.com/read/29659307/recent-advances-in-ultrasound-triggered-therapy
#6
Chaopin Yang, Yue Li, Meng Du, Zhiyi Chen
As a non-invasive and real-time diagnostic technique, ultrasound has provided a novel strategy for targeted treatment. With the rapid development of ultrasonic technique and ultrasound contrast agents (UCAs), spatiotemporally controllable application of ultrasound with or without UCAs makes it possible for site-specific delivery of therapeutic agents and targeted modulation with minimal side effects, which indicated a promising therapy in clinical use. This review will describe the main mechanism of targeted therapy induced by ultrasound briefly, then focus on the current application of ultrasound mediated targeted therapy in various fields including tumor, cardiovascular disease, central nervous system, skeletal muscle system diseases and stem cells therapy...
April 16, 2018: Journal of Drug Targeting
https://www.readbyqxmd.com/read/29626655/complications-and-cost-of-single-stage-vs-two-stage-bilateral-unicompartmental-knee-arthroplasty-a-case-control-study
#7
C Siedlecki, P Beaufils, B Lemaire, N Pujol
BACKGROUND: Single-stage bilateral knee arthroplasty, even when unicompartmental, remains controversial, chiefly due to the risk of peri-operative complications. The primary objective of this study was to compare the short-term complication rate and cost of single- vs. two-stage bilateral unicompartmental knee arthroplasty (UCA). The secondary objective was to compare total hospital stay lengths and motion-range recovery. HYPOTHESIS: Single-stage bilateral UCA is a cost-saving alternative that is not associated with higher complication rates compared to two-stage bilateral UCA...
April 4, 2018: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/29606871/ultrasound-molecular-imaging-of-breast-cancer-in-mcf-7-orthotopic-mice-using-gold-nanoshelled-poly-lactic-co-glycolic-acid-nanocapsules-a-novel-dual-targeted-ultrasound-contrast-agent
#8
Li Xu, Jing Du, Caifeng Wan, Yu Zhang, Shaowei Xie, Hongli Li, Hong Yang, Fenghua Li
Background: The development of nanoscale molecularly targeted ultrasound contrast agents (UCAs) with high affinity and specificity is critical for ultrasound molecular imaging in the early detection of breast cancer. Purpose: To prospectively evaluate ultrasound molecular imaging with dual-targeted gold nanoshelled poly(lactide-co-glycolic acid) nanocapsules carrying vascular endothelial growth factor receptor type 2 (VEGFR2) and p53 antibodies (DNCs) in MCF-7 orthotopic mice model...
2018: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/29594851/endocavitary-contrast-enhanced-ultrasound-ceus-a-novel-problem-solving-technique
#9
REVIEW
G T Yusuf, C Fang, D Y Huang, M E Sellars, A Deganello, P S Sidhu
Contrast-enhanced ultrasound (CEUS) is a technique that has developed as an adjunct to conventional ultrasound. CEUS offers a number of benefits over conventional axial imaging with computerised tomography and magnetic resonance imaging, primarily as a "beside" test, without ionising radiation or the safety concerns associated with iodinated/gadolinium-based contrast agents. Intravascular use of ultrasound contrast agents (UCAs) is widespread with extensive evidence for effective use. Despite this, the potential utility of UCAs in physiological and non-physiological cavities has not been fully explored...
March 28, 2018: Insights Into Imaging
https://www.readbyqxmd.com/read/29582136/unexplained-cardiac-arrest-a-tale-of-conflicting-interpretations-of-kcnq1-genetic-test-results
#10
Han Chow Chua, Helge Servatius, Babken Asatryan, André Schaller, Claudine Rieubland, Fabian Noti, Jens Seiler, Laurent Roten, Samuel H Baldinger, Hildegard Tanner, Juerg Fuhrer, Andreas Haeberlin, Anna Lam, Stephan A Pless, Argelia Medeiros-Domingo
OBJECTIVE: Unexplained cardiac arrest (UCA) is often the first manifestation of an inherited arrhythmogenic disease. Genetic testing in UCA is challenging due to the complexities of variant interpretation in the absence of supporting cardiac phenotype. We aimed to investigate if a KCNQ1 variant [p.(Pro64_Pro70del)], previously reported as pathogenic, contributes to the long-QT syndrome phenotype, co-segregates with disease or affects KCNQ1 function in vitro. METHODS: DNA was extracted from peripheral blood of a 22-year-old male after resuscitation from UCA...
March 26, 2018: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/29552516/first-international-symposium-uniportal-vats-international-course-uniportal-vats-buenos-aires-argentina
#11
Gustavo J Bondulich
This is a report of the first three days Uniportal VATS International Meeting. The conference included oral presentations at the Universidad Catolica Argentina (UCA), on the first day. Live Surgery from Shanghai Pulmonary Hospital, Tongji University, China, and Clinica San Camilo. Bs As, Argentina on the second day and a Wet lab in Fundación Triada Mininvasiva, Fatima Pilar on the final day.
2018: Journal of Visualized Surgery
https://www.readbyqxmd.com/read/29522835/annexin-v-conjugated-nanobubbles-a-novel-ultrasound-contrast-agent-for-in-vivo-assessment-of-the-apoptotic-response-in-cancer-therapy
#12
Tian Zhou, Wenbin Cai, Hengli Yang, Huizhong Zhang, Minghua Hao, Lijun Yuan, Jie Liu, Li Zhang, Yilin Yang, Xi Liu, Jianling Deng, Ping Zhao, Guodong Yang, Yunyou Duan
In vivo assessment of apoptotic response to cancer therapy is believed to be very important for optimizing management of treatment. However, few noninvasive strategies are currently available to monitor the therapeutic response in vivo. Ultrasonography has been used to detect apoptotic cell death in vivo, but a high-frequency transducer is needed. Fortunately, the capability of ultrasound contrast agents (UCAs) to exit the leaky vasculature of tumors enables ultrasound-targeted imaging of molecular events in response to cancer therapy...
April 28, 2018: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/29508011/imaging-with-ultrasound-contrast-agents-current-status-and-future
#13
REVIEW
Wui K Chong, Virginie Papadopoulou, Paul A Dayton
Microbubble ultrasound contrast agents (UCAs) were recently approved by the Food and Drug administration for non-cardiac imaging. The physical principles of UCAs, methods of administration, dosage, adverse effects, and imaging techniques both current and future are described. UCAs consist of microbubbles in suspension which strongly interact with the ultrasound beam and are readily detectable by ultrasound imaging systems. They are confined to the blood pool when administered intravenously, unlike iodinated and gadolinium contrast agents...
April 2018: Abdominal Radiology
https://www.readbyqxmd.com/read/29497045/preparation-and-imaging-investigation-of-dual-targeted-c-3-f-8-filled-plga-nanobubbles-as-a-novel-ultrasound-contrast-agent-for-breast-cancer
#14
Jing Du, Xiao-Yu Li, He Hu, Li Xu, Shi-Ping Yang, Feng-Hua Li
Molecularly-targeted contrast enhanced ultrasound (US) imaging is a promising imaging strategy with large potential for improving diagnostic accuracy of conventional US imaging in breast cancer detection. Therefore, we constructed a novel dual-targeted nanosized US contrast agent (UCA) directed at both vascular endothelial growth factor receptor 2 (VEGFR2) and human epidermal growth factor receptor 2 (HER2) based on perfluoropropane (C3 F8 )-filled poly(lactic-co-glycolic acid) (PLGA) (NBs) for breast cancer detection...
March 1, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29464533/photo-induced-toxicity-in-early-life-stage-fiddler-crab-uca-longisignalis-following-exposure-to-deepwater-horizon-oil
#15
Leigh M Damare, Kristin N Bridges, Matthew M Alloy, Thomas E Curran, Brianne K Soulen, Heather P Forth, Claire R Lay, Jeffrey M Morris, James A Stoeckel, Aaron P Roberts
The 2010 explosion of the Deepwater Horizon (DWH) oil rig led to the release of millions of barrels of oil in the Gulf of Mexico. Oil in aquatic ecosystems exerts toxicity through multiple mechanisms, including photo-induced toxicity following co-exposure with UV radiation. The timing and location of the spill coincided with both fiddler crab reproduction and peak yearly UV intensities, putting early life stage fiddler crabs at risk of injury due to photo-induced toxicity. The present study assessed sensitivity of fiddler crab larvae to photo-induced toxicity during co-exposure to a range of environmentally relevant dilutions of high-energy water accommodated fractions of DWH oil, and either <10, 50, or 100% ambient sunlight, achieved with filters that allowed for variable UV penetration...
May 2018: Ecotoxicology
https://www.readbyqxmd.com/read/29462468/the-impact-of-vitamin-d-status-and-parameters-of-calcium-metabolism-in-patients-with-primary-hyperparathyroidism
#16
L Tripto-Shkolnik, A Jaffe, Y Liel
Background: There is ample evidence associating vitamin D deficiency in primary hyperparathyroidism (PHP) patients with more severe disease manifestations and increased risk of postoperative hypocalcemia. Yet, there is limited data regarding the safety of vitamin D repletion in these patients. Aim: To assess the safety of vitamin D repletion in PHP patients in a real-world setting. Design: We included patients with asymptomatic PHP and few symptomatic patients who declined surgery, followed in our clinic, and treated on a routine basis with 2000 IU/day of vitamin D3...
February 1, 2018: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/29444782/are-efforts-to-attract-graduate-applicants-to-uk-medical-schools-effective-in-increasing-the-participation-of-under-represented-socioeconomic-groups-a-national-cohort-study
#17
Ben Kumwenda, Jennifer Cleland, Rachel Greatrix, Rhoda Katharine MacKenzie, Gordon Prescott
INTRODUCTION: Attracting graduates was recommended as a means of diversifying the UK medical student population. Graduates now make up nearly a quarter of the total medical student population. Research to date has focused on comparing the sociodemographic characteristics of applicants to and/or students on traditional and graduate entry programmes (GEMs), yet GEMs account for only 40% of the graduate medical student population. Thus, we aimed to compare the sociodemographic characteristic and outcomes of graduates and non-graduate applicants across a range of programmes...
February 14, 2018: BMJ Open
https://www.readbyqxmd.com/read/29439495/active-electro-location-of-objects-in-the-underwater-environment-based-on-the-mixed-polarization-multiple-signal-classification-algorithm
#18
Yidong Xu, Wenjing Shang, Lili Guo, Junwei Qi, Yingsong Li, Wei Xue
This article proposes a novel active localization method based on the mixed polarization multiple signal classification (MP-MUSIC) algorithm for positioning a metal target or an insulator target in the underwater environment by using a uniform circular antenna (UCA). The boundary element method (BEM) is introduced to analyze the boundary of the target by use of a matrix equation. In this method, an electric dipole source as a part of the locating system is set perpendicularly to the plane of the UCA. As a result, the UCA can only receive the induction field of the target...
February 11, 2018: Sensors
https://www.readbyqxmd.com/read/29423461/how-to-perform-contrast-enhanced-ultrasound-ceus
#19
REVIEW
Christoph F Dietrich, Michalakis Averkiou, Michael Bachmann Nielsen, Richard G Barr, Peter N Burns, Fabrizio Calliada, Vito Cantisani, Byung Choi, Maria C Chammas, Dirk-André Clevert, Michel Claudon, Jean-Michel Correas, Xin-Wu Cui, David Cosgrove, Mirko D'Onofrio, Yi Dong, JohnR Eisenbrey, Teresa Fontanilla, Odd Helge Gilja, Andre Ignee, Christian Jenssen, Yuko Kono, Masatoshi Kudo, Nathalie Lassau, Andrej Lyshchik, Maria Franca Meloni, Fuminori Moriyasu, Christian Nolsøe, Fabio Piscaglia, Maija Radzina, Adrian Saftoiu, Paul S Sidhu, Ioan Sporea, Dagmar Schreiber-Dietrich, Claude B Sirlin, Maria Stanczak, Hans-Peter Weskott, Stephanie R Wilson, Juergen Karl Willmann, Tae Kyoung Kim, Hyun-Jung Jang, Alexandar Vezeridis, Sue Westerway
"How to perform contrast-enhanced ultrasound (CEUS)" provides general advice on the use of ultrasound contrast agents (UCAs) for clinical decision-making and reviews technical parameters for optimal CEUS performance. CEUS techniques vary between centers, therefore, experts from EFSUMB, WFUMB and from the CEUS LI-RADS working group created a discussion forum to standardize the CEUS examination technique according to published evidence and best personal experience. The goal is to standardise the use and administration of UCAs to facilitate correct diagnoses and ultimately to improve the management and outcomes of patients...
January 2018: Ultrasound International Open
https://www.readbyqxmd.com/read/29415488/analytic-and-unambiguous-phase-based-algorithm-for-3-d-localization-of-a-single-source-with-uniform-circular-array
#20
Le Zuo, Jin Pan, Boyuan Ma
This paper presents an analytic algorithm for estimating three-dimensional (3-D) localization of a single source with uniform circular array (UCA) interferometers. Fourier transforms are exploited to expand the phase distribution of a single source and the localization problem is reformulated as an equivalent spectrum manipulation problem. The 3-D parameters are decoupled to different spectrums in the Fourier domain. Algebraic relations are established between the 3-D localization parameters and the Fourier spectrums...
February 6, 2018: Sensors
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