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https://www.readbyqxmd.com/read/29341456/iron-pill-aspiration-cytologic-and-histologic-findings-of-a-potential-life-threatening-airway-injury-a-case-report-and-literature-review
#1
Vanessa Henriques, Diogo Costa Santos, Graça Lérias, Lucília Cáceres Monteiro
Iron pill-induced injury of bronchial mucosa is a complication following accidental aspiration of an iron tablet. Oral iron supplementation is a common therapy, particularly among advanced-age patients, who are more prone to aspiration. However, iron pill aspiration has been rarely reported in the literature, usually under the format of short case reports, with only 32 cases published in the literature. The cytologic features suspicious for this rare but potentially lethal entity have been seldom described...
January 16, 2018: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/29337625/molecular-characterization-of-qx-like-and-variant-infectious-bronchitis-virus-strains-in-malaysia-based-on-partial-genomic-sequences-comprising-the-s-3a-3b-e-m-intergenic-region-5a-5b-n-gene-order
#2
N P Khanh, S W Tan, S K Yeap, D A Satharasinghe, M Hair-Bejo, T N Bich, A R Omar
Infectious bronchitis virus (IBV) is one of the major poultry pathogens of global importance. However, the prevalence of IBV strains in Malaysia is poorly characterized. The partial genomic sequences (6.8 kb) comprising the S-3a/3b-E-M-intergenic region-5a/5b-N gene order of 11 Malaysian IBVs isolated in 2014 and 2015 were sequenced using next-generation sequencing technology. Phylogenetic and pairwise sequence comparison analysis showed that the isolated IBVs are divided into two groups. Group 1 (IBS124/2015, IBS125/2015, IBS126/2015, IBS130/2015, IBS131/2015, IBS138/2015, and IBS142/2015) shared 90%-95% nucleotide and deduced amino acid similarities to the QX-like strain...
December 2017: Avian Diseases
https://www.readbyqxmd.com/read/29337615/efficacy-of-massachusetts-and-793b-vaccines-against-infectious-bronchitis-moroccan-italy-02-virus-in-specific-pathogen-free-chickens-and-commercial-broilers
#3
Sakhia F Z Belkasmi, Siham Fellahi, Sajid Umar, Mattias Delpont, Maxence Delverdier, Marie-Noëlle Lucas, Céline Bleuart, Faouzi Kichou, Saâdia Nassik, Jean-Luc Guerin, Ouafaa Fassi Fihri, Mariette F Ducatez, Mohammed El Houadfi
The ability of commercial vaccines H120 and 4/91 to protect against Moroccan-Italy 02 infectious bronchitis virus (Mor-It02) was investigated in specific-pathogen-free (SPF) chickens and commercial broiler chickens. Commercial broiler chicks (Experiment 1) were vaccinated at the hatchery with H120 vaccine at Day 1, and challenged at Day 21 with 104 50% egg-infective dose (EID50) of Mor-It02. All chicks were observed daily for clinical signs attributable to Mor-It02 infection during the 10 days postchallenge (pc)...
December 2017: Avian Diseases
https://www.readbyqxmd.com/read/29333034/antinociceptive-and-anti-inflammatory-effects-of-triterpenes-from-pluchea-quitoc-dc-aerial-parts
#4
Francisco Alcione Nobre da Silva, Sônia Maria de Farias Freire, Marilene Oliveira da Rocha Borges, Francisco Erivaldo Vidal Barros, Maria da de Sousa, Maria Nilce de Sousa Ribeiro, Giselle Maria Skelding Pinheiro Guilhon, Adolfo Henrique Müller, Antonio Carlos Romão Borges
Background: Pluchea quitoc DC. (Asteraceae), a medicinal plant known as "quitoco," "caculucage," "tabacarana" and "madre-cravo," is indicated for inflammatory conditions such as bronchitis, arthritis, and inflammation in the uterus and digestive system. Objective: This study evaluated the analgesic and anti-inflammatory activities of the triterpenes compounds obtained from P. quitoc aerial parts. Materials and Methods: The triterpenes compounds β-amyrin, taraxasterol and pseudo-taraxasterol in a mixture (T); β-amyrin, taraxasterol and pseudo-taraxasterol acetates in a mixture (Ta); β-amyrin, taraxasterol, pseudo-taraxasterol acetates in a mixture with β-amyrin, taraxasterol and pseudo-taraxasterol myristates (Tafe) were analyzed in the models of nociception and inflammation...
December 2017: Pharmacognosy Research
https://www.readbyqxmd.com/read/29332648/prevalence-of-chronic-respiratory-diseases-from-a-rural-area-in-kerala-southern-india
#5
Krishnaveni Viswanathan, P S Rakesh, Shibu Balakrishnan, A Shanavas, Varun Dharman
BACKGROUND: Chronic lung diseases are one of the leading causes of morbidity in developing countries. A community based survey was undertaken with an objective to estimate the prevalence of chronic respiratory diseases and to describe the profile of people with CRDs in the rural area Nilamel health block in Kollam district, Kerala, southern India. METHODS: A household information sheet and a translated respiratory symptom questionnaire based on International Union against Tuberculosis and Lung Disease (IUATLD) bronchial symptoms questionnaire was administered to 12,556 people above 15 years, selected randomly from Nilamel health block...
January 2018: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/29330815/supplementing-dietary-rosemary-rosmarinus-officinalis-l-powder-and-vitamin-e-in-broiler-chickens-evaluation-of-humoral-immune-response-lymphoid-organs-and-blood-proteins
#6
Hossein Rostami, Alireza Seidavi, Mohammad Dadashbeiki, Yadollah Asadpour, João Simões, Assar Ali Shah, Vito Laudadio, Caterina Losacco, Antonella Perillo, Vincenzo Tufarelli
The aim of the present study was to evaluate the effect rosemary (Rosmarinus officinalis L.) powder (RP) and vitamin E (VE) at different levels on humoral immunity of broilers during a 42-day production cycle. A total of 270 1-day-old male chicks were assigned to nine groups with three replicates of ten birds each, and diets were supplemented with 0, 0.5, or 1.0% RP and 0, 100, or 200 mg/kg VE, respectively. Commercial-inactivated vaccines against avian influenza (AI) and Newcastle disease (ND) viruses, and living infectious bronchitis virus (IBV) vaccine were administered by spray method...
January 12, 2018: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29330060/induction-of-innate-immune-response-following-introduction-of-infectious-bronchitis-virus-ibv-in-the-trachea-and-renal-tissues-of-chickens
#7
Xin Yang, Jianan Li, Hui Liu, Peng Zhang, Danyu Chen, Shuai Men, Xiaocheng Li, Hongning Wang
Infectious bronchitis (IB) is a highly contagious respiratory disease of chickens, which is caused by the infectious bronchitis virus (IBV). The innate immune response is crucial for antiviral infections and revealing the pathogenic mechanisms of IBV. In this study, we presents an evaluation of interferon (I, II and III IFNs) in renal and tracheal samples from chickens experimentally infected previously vaccinated or not. The results suggest differential expression of chicken interferon, among them type I IFN elaborate a major role in fighting off virus...
January 9, 2018: Microbial Pathogenesis
https://www.readbyqxmd.com/read/29327786/differential-effects-of-experimental-hyperthyroidism-on-declined-immunity-of-broiler-chicken
#8
M S Khilji, M A Sandhu, M S Yousaf, A A Saeed, H U Rehman, H Zaneb, M A Rashid
Thyroid hormones (THs) are involved in the development of lymphoid organs and regulation of immune function in birds. However, their role as an immune-modulator in the hyperthyroid state is still debatable. To explore the interrelationship of thyroxine (T4 ) and the immune system, chicks were divided into three groups. Group I was comprised of control birds, who received the basal diet while group II and III were given diets supplemented with 5 μg and 10 μg thyroxine/kg feed, respectively, from 15 to 28 days of age...
January 12, 2018: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/29324762/obesogenic-diets-alter-metabolism-in-mice
#9
Megan R Showalter, Eric B Nonnecke, A L Linderholm, Tomas Cajka, Michael R Sa, Bo Lönnerdal, Nicholas J Kenyon, Oliver Fiehn
Obesity and accompanying metabolic disease is negatively correlated with lung health yet the exact mechanisms by which obesity affects the lung are not well characterized. Since obesity is associated with lung diseases as chronic bronchitis and asthma, we designed a series of experiments to measure changes in lung metabolism in mice fed obesogenic diets. Mice were fed either control or high fat/sugar diet (45%kcal fat/17%kcal sucrose), or very high fat diet (60%kcal fat/7% sucrose) for 150 days. We performed untargeted metabolomics by GC-TOFMS and HILIC-QTOFMS and lipidomics by RPLC-QTOFMS to reveal global changes in lung metabolism resulting from obesity and diet composition...
2018: PloS One
https://www.readbyqxmd.com/read/29322720/invasive-aspergillus-pseudomembranous-and-obstructive-tracheo-bronchitis-in-an-immuno-competent-patient
#10
Ramesh S Pal, Sonam Spalgais, Amit Kumar Murar, Umesh Chandra Ojha
A 19 year female, presented with life threatening haemoptysis and cough with minimum expectoration for 3 months. Bronchoscopy showed multiple nodules in airway. The direct microscopy and culture of sputum revealed fungal elements and Aspergillus flavus respectively. Serum Galactomannan was positive. Thus diagnosis of invasive aspergillus tracheo-bronchitis made. She responded to voriconazole. Aspergillus tracheo-bronchitis is a rare form of invasive pulmonary aspergillosis in immuno-competent host. Aspergillus spp in respiratory samples should not be routinely discarded as colonization...
November 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/29317659/clinical-outcome-of-eosinophilic-airway-inflammation-in-chronic-airway-diseases-including-nonasthmatic-eosinophilic-bronchitis
#11
Jaeyoung Cho, Sun Mi Choi, Jinwoo Lee, Young Sik Park, Sang-Min Lee, Chul-Gyu Yoo, Young Whan Kim, Sung Koo Han, Chang-Hoon Lee
We enrolled patients with confirmed sputum eosinophilia who had visited our tertiary referral hospital between 2012 and 2015. We evaluated the incidence and predictors of exacerbations in patients with nonasthmatic eosinophilic bronchitis (NAEB), and investigated predictors of improvement in eosinophilic inflammation in chronic airway diseases with or without persistent airflow limitation. In total, 398 patients with sputum eosinophilia were enrolled. Of these, 152 (38.2%) had NAEB. The incidence rate of exacerbations requiring treatment with antibiotics, systemic corticosteroids, or hospital admission was 0...
January 9, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29316764/-an-investigation-to-an-accident-of-occupational-trichloroethylene-explosion
#12
L J Yu, X D Jian, W J Wang, Y Z Wu, K Wang, J E Jia, Z C Zhang
Objective: To investigation to an accident of occupational trichloroethylene explosion and analyze the clinical datas. Methods: An investigation was carried out on the explosion of trichloroethylene in a place in shandong province in June 2016, and the clinical data of 4 patients with trichloroethylene poisoning were analyzed. Results: The incident is caused by irregularities in workers, 4 patients were characterized by different levels of the respiratory system, nervous system, liver, and skin lesions. Among them, respiratory system damage was more prominent, mainly manifested as chemical bronchitis and pneumonia, after positive rescue and treatment all recovered and discharged...
November 20, 2017: Chinese Journal of Industrial Hygiene and Occupational Diseases
https://www.readbyqxmd.com/read/29313707/sputum-eosinophilia-and-mri-ventilation-heterogeneity-in-severe-asthma
#13
Sarah Svenningsen, Rachel L Eddy, Hui Fang Lim, P Gerard Cox, Parameswaran Nair, Grace Parraga
RATIONALE: Inflammation and smooth muscle dysfunction are integral components of severe asthma that contribute to luminal obstruction causing airflow limitation, ventilation heterogeneity and symptoms. This is important for guiding treatment decisions directed at inflammatory (eg. anti-Th2 monoclonal antibodies) and non-inflammatory, smooth muscle-mediated (eg. bronchial thermoplasty) components of severe asthma. OBJECTIVE: To investigate the contribution of eosinophilic-bronchitis and smooth muscle dysfunction to magnetic-resonance-imaging (MRI) ventilation heterogeneity in severe asthmatics...
January 9, 2018: American Journal of Respiratory and Critical Care Medicine
https://www.readbyqxmd.com/read/29312734/posterior-uniportal-video-assisted-thoracoscopic-surgery-for-anatomical-lung-resections
#14
Davor Stamenovic, Korkut Bostanci, Antje Messerschmidt
Background: The acceptance of uniportal video-assisted thoracoscopic surgery (uVATS) for anatomical lung resections has been growing in recent years. This study presents the first case-series in the literature with posterior uVATS (puVATS) technique for specific anatomical lung resections. Methods: The first 20 consecutive patients who underwent an anatomical lung resection by a single surgeon, by means of puVATS technique were evaluated in terms of pre-, peri- and post-operative results...
December 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29312718/chronic-bronchitis-is-associated-with-severe-exacerbation-and-prolonged-recovery-period-in-chinese-patients-with-copd-a-multicenter-cross-sectional-study
#15
Ying Liang, Yahong Chen, Rui Wu, Ming Lu, Wanzhen Yao, Jian Kang, Baiqiang Cai, Xin Zhou, Zheng Liu, Ping Chen, Dejun Sun, Jingping Zheng, Guoyang Wang, Yulin Feng, Yongjian Xu
Background: Chronic bronchitis (CB) is closely associated with the frequency and severity of chronic obstructive pulmonary disease (COPD) exacerbation. However, little is known about the impact of CB on COPD exacerbations, severe and non-severe, and on recovery from an exacerbation. Methods: We conducted a nation-wide multicenter cross-sectional survey in China between September 2007 and December 2008. Eleven hospitals participated in this study. Patients' demographic information, presence of CB, overall numbers of COPD exacerbation and severe exacerbation leading to emergency visit, hospitalization and intensive care unit (ICU) stay in the past year, recovery period following the last exacerbation, and well- or poor-recovery were recorded...
December 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29308548/management-of-recurrent-preschool-doctor-diagnosed-wheeze
#16
REVIEW
Ka-Ka Siu, Shuk-Yu Leung, Sum-Yi Kong, Daniel Kwok-Keung Ng
Preschool wheeze occurs in half of the children before they reach 6 y of age and recurrence is also common. Recurrent preschool wheeze is classified as either typical or atypical. For typical recurrent preschool wheeze, the diagnoses are either asthma or bronchiolitis/bronchitis. Responsiveness to a properly administered bronchodilator confirms asthma, atopic or otherwise. All atypical preschool wheeze should be referred to pediatric respirologist for assessment. Lung function test by impulse oscillometry (IOS) before and after bronchodilator is helpful to confirm airway hyperresponsiveness, an essential feature of asthma...
January 8, 2018: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29307719/tandem-mass-tags-labeled-quantitative-proteomics-to-study-the-effect-of-tobacco-smoke-exposure-on-the-rat-lung
#17
Shuangshuang Ma, Chunguo Wang, Baosheng Zhao, Xiaolei Ren, Simin Tian, Juan Wang, Chi Zhang, Yuanyang Shao, Minyi Qiu, Xueyong Wang
BACKGROUND: The causal link between tobacco smoke exposure (TSE) and numerous severe respiratory system diseases (RSD), including chronic bronchitis, chronic obstructive pulmonary disease, and lung cancer, is well established. However, the pathogenesis of TSE-induced RSD remains incompletely understood. This research aims to detect the pathogenetic mechanisms and potential therapeutic targets of TSE-induced RSD. METHODS: this study employed TSE model which rats were exposed to a concentration of 60% tobacco smoke in a toxicant exposure system for four weeks...
January 4, 2018: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/29304074/absolute-lung-size-and-the-sex-difference-in-breathlessness-in-the-general-population
#18
Magnus Ekström, Josefin Sundh, Linus Schiöler, Eva Lindberg, Annika Rosengren, Göran Bergström, Oskar Angerås, Jan Hedner, John Brandberg, Björn Bake, Kjell Torén
BACKGROUND: Breathlessness is associated with major adverse health outcomes and is twice as common in women as men in the general population. We evaluated whether this is related to their lower absolute lung volumes. METHODS: Cross-sectional analysis of the population-based Swedish CardioPulmonarybioImage Study (SCAPIS) Pilot, including static spirometry and diffusing capacity (n = 1,013; 49% women). Breathlessness was measured using the modified Medical Research Council (mMRC) scale and analyzed using ordinal logistic regression adjusting for age, pack-years of smoking, body mass index, chronic airway limitation, asthma, chronic bronchitis, depression and anxiety in all models...
2018: PloS One
https://www.readbyqxmd.com/read/29302792/mitochondrial-bioenergy-alterations-in-avian-hd11-macrophages-infected-with-infectious-bronchitis-virus
#19
Sergio E L da Silva, Helena L Ferreira, Andrea F Garcia, Felipe E S Silva, Roberto Gameiro, Carolina U F Fabri, Dielson S Vieira, Tereza C Cardoso
To establish an association between mitochondrial dysfunction and apoptosis following infectious bronchitis virus (IBV) infection, HD11 avian macrophage cells were infected with the Massachusetts 41 (M41) strain. Our results show that the M41 strain of IBV induced cytopathic effects followed by the release of new viral particles. Elevated numbers of apoptotic cells were observed at 24, 48 and 72 h post-infection (p.i.). Viral infection was associated with mitochondrial membrane depolarization and reactive oxygen species (ROS) production at all of the examined timepoints p...
January 4, 2018: Archives of Virology
https://www.readbyqxmd.com/read/29302540/a-chart-review-of-morbidity-patterns-among-adult-patients-attending-primary-care-setting-in-urban-odisha-india-an-international-classification-of-primary-care-experience
#20
Subhashisa Swain, Sandipana Pati, Sanghamitra Pati
Introduction: Disease burden estimations based on sound epidemiological research provide the foundation for designing health services. Patients visiting a primary care often present with symptoms and signs. Understanding the burden is crucial for developing countries including India. The project aimed to record the reasons for encounter (RFE) at primary care settings for estimating the burden at the health-care facility. Methodology: This cross-sectional study was undertaken at four urban health dispensaries of Bhubaneswar, Odisha, with the aim to explore the prevailing patterns of diseases among patients attending these facilities...
April 2017: Journal of Family Medicine and Primary Care
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