keyword
MENU ▼
Read by QxMD icon Read
search

Bronchitis

keyword
https://www.readbyqxmd.com/read/28937583/infectious-bronchitis-virus-variants-molecular-analysis-and-pathogenicity-investigation
#1
REVIEW
Shu-Yi Lin, Hui-Wen Chen
Infectious bronchitis virus (IBV) variants constantly emerge and pose economic threats to poultry farms worldwide. Numerous studies on the molecular and pathogenic characterization of IBV variants have been performed between 2007 and 2017, which we have reviewed herein. We noted that viral genetic mutations and recombination events commonly gave rise to distinct IBV genotypes, serotypes and pathotypes. In addition to characterizing the S1 genes, full viral genomic sequencing, comprehensive antigenicity, and pathogenicity studies on emerging variants have advanced our understanding of IBV infections, which is valuable for developing countermeasures against IBV field outbreaks...
September 22, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28934727/in-utero-exposure-to-select-phenols-and-phthalates-and-respiratory-health-in-five-year-old-boys-a-prospective-study
#2
Céline Vernet, Isabelle Pin, Lise Giorgis-Allemand, Claire Philippat, Meriem Benmerad, Joane Quentin, Antonia M Calafat, Xiaoyun Ye, Isabella Annesi-Maesano, Valérie Siroux, Rémy Slama
BACKGROUND: Phenols and phthalates may have immunomodulatory and proinflammatory effects and thereby adversely affect respiratory health. OBJECTIVE: We estimated the associations between gestational exposure to select phthalates and phenols and respiratory health in boys. METHODS: Among 587 pregnant women from the EDEN (Etude des Déterminants pré et post natals du développement et de la santé de l'Enfant) cohort who delivered a boy, 9 phenols and 11 phthalates metabolites were quantified in spot pregnancy urine samples...
September 8, 2017: Environmental Health Perspectives
https://www.readbyqxmd.com/read/28934249/variability-in-objective-and-subjective-measures-affects-baseline-values-in-studies-of-patients-with-copd
#3
Wayne H Anderson, Jae Wook Ha, David J Couper, Wanda K O'Neal, R Graham Barr, Eugene R Bleecker, Elizabeth E Carretta, Christopher B Cooper, Claire M Doerschuk, M Bradley Drummond, MeiLan K Han, Nadia N Hansel, Victor Kim, Eric C Kleerup, Fernando J Martinez, Stephen I Rennard, Donald Tashkin, Prescott G Woodruff, Robert Paine, Jeffrey L Curtis, Richard E Kanner
RATIONALE: Understanding the reliability and repeatability of clinical measurements used in the diagnosis, treatment and monitoring of disease progression is of critical importance across all disciplines of clinical practice and in clinical trials to assess therapeutic efficacy and safety. OBJECTIVES: Our goal is to understand normal variability for assessing true changes in health status and to more accurately utilize this data to differentiate disease characteristics and outcomes...
2017: PloS One
https://www.readbyqxmd.com/read/28933760/infectious-bronchitis-virus-infection-induces-apoptosis-during-replication-in-chicken-macrophage-hd11-cells
#4
Xiaoxiao Han, Yiming Tian, Ru Guan, Wenqian Gao, Xin Yang, Long Zhou, Hongning Wang
Avian infectious bronchitis has caused huge economic losses in the poultry industry. Previous studies have reported that infectious bronchitis virus (IBV) infection can produce cytopathic effects (CPE) and apoptosis in some mammalian cells and primary cells. However, there is little research on IBV-induced immune cell apoptosis. In this study, chicken macrophage HD11 cells were established as a cellular model that is permissive to IBV infection. Then, IBV-induced apoptosis was observed through a cell viability assay, morphological changes, and flow cytometry...
July 26, 2017: Viruses
https://www.readbyqxmd.com/read/28931794/health-effects-of-air-pollution-a-historical-review-and-present-status
#5
Masayuki Shima
During the 1960s, the concentrations of air pollutants, particularly that of sulfur dioxide (SO2), were extremely high in many industrial cities in Japan, and the prevalence of bronchial asthma and chronic bronchitis increased among residents living in the cities. To evaluate the effects of air pollution on respiratory diseases, many epidemiological studies were conducted, and the findings played an important role in the regulatory control of air pollution. After 1970, the concentration of SO2 has decreased markedly, and its adverse health effects have been minimized...
2017: Nihon Eiseigaku Zasshi. Japanese Journal of Hygiene
https://www.readbyqxmd.com/read/28930224/aromatic-medicinal-plants-of-the-lamiaceae-family-from-uzbekistan-ethnopharmacology-essential-oils-composition-and-biological-activities
#6
REVIEW
Nilufar Z Mamadalieva, Davlat Kh Akramov, Elisa Ovidi, Antonio Tiezzi, Lutfun Nahar, Shahnoz S Azimova, Satyajit D Sarker
Plants of the Lamiaceae family are important ornamental, medicinal, and aromatic plants, many of which produce essential oils that are used in traditional and modern medicine, and in the food, cosmetics, and pharmaceutical industry. Various species of the genera Hyssopus, Leonurus, Mentha, Nepeta, Origanum, Perovskia, Phlomis, Salvia, Scutellaria, and Ziziphora are widespread throughout the world, are the most popular plants in Uzbek traditional remedies, and are often used for the treatment of wounds, gastritis, infections, dermatitis, bronchitis, and inflammation...
February 10, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/28929588/bioactive-compounds-of-shuang-huang-lian-prescription-and-an-insight-into-its-binding-mechanism-by-%C3%AE-2-adrenoceptor-chromatography-coupled-with-site-directed-molecular-docking
#7
Jing Wang, Fengwu Li, Kaizhu Zeng, Qian Li, Xinfeng Zhao, Xiaohui Zheng
Owing to the promising clinical efficacy and relatively simple composition, Shuang-Huang-Lian prescription is widely prescribed for the treatment of acute upper respiratory tract infection and acute bronchitis in practice. This necessitates the understanding of the bioactive compounds of the prescription and their binding mechanism to β2-adrenoceptor, which mediates the aforementioned ailments. In this work, a column containing immobilized β2-adrenoceptor was prepared using a diazonium salt reaction. The bioactive compound collected from the β2-adrenoceptor column was identified as chlorogenic acid by using high-performance liquid chromatography coupled with ion trap mass spectrometry...
September 20, 2017: Journal of Separation Science
https://www.readbyqxmd.com/read/28929236/-criteria-for-treating-mrsa-in-sputum
#8
REVIEW
J Lorenz, M Unnewehr, B Schaaf, S Gatermann
Methicillin-resistant strains of Staphylococcus aureus (MRSA) are of particular significance for the management of patients with airway infections, since the disease course is often complicated and treatment rendered difficult by multiple resistance. Their prevalence is now slowly declining, but still alarmingly high. Hospital-acquired infections are predominant, but hospital-associated and community-acquired infections do occur, as do rare infections with livestock-acquired strains. Non-nosocomial strains are characterized by different pathogenic factors and a different spectrum of antibacterial resistance; they often have a threatening disease course...
September 19, 2017: Der Internist
https://www.readbyqxmd.com/read/28926203/qualitative-and-quantitative-analysis-of-chemical-constituents-in-ardisiae-japonicae-herba
#9
Ke-Yun Yu, Wen Gao, Shang-Zhen Li, Wei Wu, Pei Li, Li-Li Dou, Yuan-Zhong Wang, E-Hu Liu
Ardisiae Japonicae Herba is a well-known traditional Chinese medicine for the treatment of bronchitis conjunctivitis, pneumonia and trauma. In this work, a high-performance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry method was firstly established for the separation and structural identification of the chemical constituents in Ardisiae Japonicae Herba. A total of 15 compounds including coumarins, flavonoid glycosides, and catechins were identified or tentatively characterized based on their chromatographic behaviors and mass spectral fragmentation and by comparisons with the reference standards...
September 19, 2017: Journal of Separation Science
https://www.readbyqxmd.com/read/28923510/first-characterization-of-a-middle-east-gi-23-lineage-var2-like-of-infectious-bronchitis-virus-in-europe
#10
Anna Lisowska, Joanna Sajewicz-Krukowska, Alice Fusaro, Anna Pikula, Katarzyna Domanska-Blicharz
Variants assigned to GI-23 lineage of infectious bronchitis virus (IBV), formerly called Var2, have circulated for nearly 20 years only in countries of the Middle East. Strains of this lineage were first identified in Israel in 1998. More severe form of the virus appeared in 2006, when the second wave of Var2 epidemic has spread over the Middle East region. The present study describes the detection and detailed genetic characterization of the GI-23 viruses in Poland. The full-length genome of gammaCoV/Ck/Poland/G052/2016 strain consists of 27596 nucleotides and has typical organization for IBV (UTR5'-POl-S-3a-3b-E-M-5a-5b-N-UTR3')...
September 15, 2017: Virus Research
https://www.readbyqxmd.com/read/28923049/roflumilast-reverses-cftr-mediated-ion-transport-dysfunction-in-cigarette-smoke-exposed-mice
#11
S Vamsee Raju, Lawrence Rasmussen, Peter A Sloane, Li Ping Tang, Emily Falk Libby, Steven M Rowe
BACKGROUND: Dysfunction in cystic fibrosis transmembrane conductance regulator (CFTR) can be elicited by cigarette smoke and is observed in patients with chronic bronchitis. We have previously demonstrated in human airway epithelial cell monolayers that roflumilast, a clinically approved phosphodiesterase 4 inhibitor that reduces the risk of exacerbations in chronic obstructive pulmonary disease patients with chronic bronchitis and a history of exacerbations, activates CFTR-dependent chloride secretion via a cAMP-mediated pathway, partially restores the detrimental effects of cigarette smoke on CFTR-mediated ion transport, and increases CFTR-dependent gastrointestinal fluid secretion in isolated murine intestine segments...
September 18, 2017: Respiratory Research
https://www.readbyqxmd.com/read/28922566/streptococcus-pneumoniae-and-chronic-endobronchial-infections-in-childhood
#12
Kim M Hare, Amanda J Leach, Heidi C Smith-Vaughan, Anne B Chang, Keith Grimwood
Streptococcus pneumoniae (pneumococcus) is the main cause of bacterial pneumonia worldwide and has been studied extensively in this context. However, its role in chronic endobronchial infections and accompanying lower airway neutrophilic infiltration has received little attention. Severe and recurrent pneumonia are risk factors for chronic suppurative lung disease (CSLD) and bronchiectasis; the latter causes considerable morbidity and, in some populations, premature death in children and adults. Protracted bacterial bronchitis (PBB) is another chronic endobronchial infection associated with substantial morbidity...
September 18, 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/28914860/-new-opportunities-for-inhaled-therapy-for-inflammatory-diseases-of-the-respiratory-system
#13
G L Ignatova, V N Antonov
The paper considers current approaches to mucoregulatory therapy for various inflammatory diseases of the respiratory system. It gives the advantages and disadvantages of common drugs used in their treatment. Emphasis is laid on the use of inhaled hypertonic saline of NaCl in combination with hyaluronic acid (Hyaneb). Clinical examples of its use in chronic obstructive pulmonary disease, acute and chronic bronchitis, and severe asthma are considered.
2017: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/28911045/azole-resistant-aspergillosis-epidemiology-molecular-mechanisms-and-treatment
#14
REVIEW
Anuradha Chowdhary, Cheshta Sharma, Jacques F Meis
Aspergillus fumigatus remains the most common species in all pulmonary syndromes, followed by Aspergillus flavus which is a common cause of allergic rhinosinusitis, postoperative aspergillosis and fungal keratitis. The manifestations of Aspergillus infections include invasive aspergillosis, chronic pulmonary aspergillosis and bronchitis. Allergic manifestations of inhaled Aspergillus include allergic bronchopulmonary aspergillosis and severe asthma with fungal sensitization. Triazoles are the mainstay of therapy against Aspergillus infections for treatment and prophylaxis...
August 15, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28901223/the-lymphatic-system-the-achilles-heel-of-the-fontan-kreutzer-circulation
#15
Christian Kreutzer, Guillermo Kreutzer
In spite of excellent long term survival the Fontan Kreutzer procedure commonly presents late failure due to end-organ damage. Several advances have been described to refine single ventricle management and surgical techniques. However, very little research has been dedicated to the lymphatic circulation in the precarious Fontan hemodynamic state. The lymphatic circulation is clearly affected since there is increased lymph production, which requires to be drained at a similar or higher pressure than it is produced, commonly resulting in chronic lymphedema...
September 2017: World Journal for Pediatric & Congenital Heart Surgery
https://www.readbyqxmd.com/read/28899630/protection-against-infectious-bronchitis-virus-by-spike-ectodomain-subunit-vaccine
#16
Fatma Eldemery, Kellye S Joiner, Haroldo Toro, Vicky L van Santen
The avian coronavirus infectious bronchitis virus (IBV) S1 subunit of the spike (S) glycoprotein mediates viral attachment to host cells and the S2 subunit is responsible for membrane fusion. Using IBV Arkansas-type (Ark) S protein histochemistry, we show that extension of S1 with the S2 ectodomain improves binding to chicken tissues. Although the S1 subunit is the major inducer of neutralizing antibodies, vaccination with S1 protein has been shown to confer inadequate protection against challenge. The demonstrated contribution of S2 ectodomain to binding to chicken tissues suggests that vaccination with the ectodomain might improve protection compared to vaccination with S1 alone...
September 9, 2017: Vaccine
https://www.readbyqxmd.com/read/28895517/assessment-of-molecular-and-genetic-evolution-antigenicity-and-virulence-properties-during-the-persistence-of-the-infectious-bronchitis-virus-in-broiler-breeders
#17
Filipe Santos Fernando, Thaiane Coelho Kasmanas, Priscila Diniz Lopes, Maria de Fátima da Silva Montassier, Marcos Antônio Zanella Mores, Viviane Casagrande Mariguela, Caren Pavani, Romeu Moreira Dos Santos, Mário Sérgio Assayag, Helio José Montassier
The infectious bronchitis virus (IBV) causes a highly contagious disease [infectious bronchitis (IB)] that results in substantial economic losses to the poultry industry worldwide. We conducted a molecular and phylogenetic analysis of the S1 gene of Brazilian (BR) IBV isolates from a routinely vaccinated commercial flock of broiler breeders, obtained from clinical IB episodes that occurred in 24-, 46- and 62-week-old chickens. We also characterized the antigenicity, pathogenesis, tissue tropism and spreading of three IBV isolates by experimental infection of specific pathogen-free (SPF) chickens and contact sentinel birds...
September 12, 2017: Journal of General Virology
https://www.readbyqxmd.com/read/28891268/pediatric-respiratory-tract-diseases-chronological-trends-and-perspectives
#18
Houda Ben Ayed, Sourour Yaïch, Maïssa Ben Jmaa, Jihene Jedidi, Mariem Ben Hmida, Maroua Trigui, Mondher Kassis, Raouf Karray, Yosra Mejdoub, Habib Feki, Jamel Damak
BACKGROUND: We aimed to draw the epidemiological profile of respiratory tract diseases (RTD) among children in the region of Sfax and to evaluate their current trends over a 13-year period. METHODS: We conducted a retrospective study including all children hospitalized with RTD aged under 14 years. We collected data from the regional morbidity register of the university hospital of Sfax from 2003 to 2015. RESULTS: We included 10797 cases with RTD among 49880 pediatric hospitalizations (21...
September 10, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28887201/reactive-oxygen-therapy-a-novel-antimicrobial
#19
REVIEW
Matthew Dryden
The main solution to the global antibiotic resistance crisis is reducing the volume of antibiotic use in medicine, agriculture and the environment. However there is also a pressing need for novel antimicrobials. Despite much rhetoric, there are few entirely novel agents in development. One such therapy to reach clinical use is an agent using Reactive Oxygen Species (ROS), oxygen radicals, as an antimicrobial mechanism. ROS can be delivered to the site of infection in various formats. ROS is highly antimicrobial against Gram positive and negative bacteria, viruses and fungi...
September 5, 2017: International Journal of Antimicrobial Agents
https://www.readbyqxmd.com/read/28885339/role-of-chemotherapy-and-thrombolysis-in-treatment-of-choriocarcinoma-accompanied-with-pulmonary-embolism-a-case-report-with-literature-review
#20
Mei Yang, Li Peng
RATIONALE: Choriocarcinoma accompanied with pulmonary embolism (PE) is rare and difficult to diagnose and treat. There are about 25 cases reported in literature, which presented variable clinical characteristics and prognosis. PATIENT CONCERNS: We reported a case of choriocarcinoma presenting PE as the first manifestation in a 26-year-old Chinese female. DIAGNOSES: Four months before her admission to our hospital, she presented to a local hospital with respiratory manifestations, and was first diagnosed as bronchitis and treated with antibiotics without improvement, and subsequently suspected of having pulmonary tuberculosis and receive anti-tuberculosis therapy, with no response...
September 2017: Medicine (Baltimore)
keyword
keyword
7636
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"