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https://www.readbyqxmd.com/read/29923501/optimization-of-gelatin-alginate-composite-bioink-printability-using-rheological-parameters-a-systematic-approach
#1
Teng Gao, Gregory James Gillispie, Joshua S Copus, Anil Kumar Pallickaveedu Rajan Asari, Young-Joon Seol, Anthony Atala, James J Yoo, Sang Jin Jin Lee
Three-dimensional (3D) bioprinting has emerged as a promising technique in tissue engineering applications through the precise deposition of cells and biomaterials in a layer-by-layer fashion. However, the limited availability of hydrogel bioinks is frequently cited as a major issue for the advancement of cell-based extrusion bioprinting technologies. It is well known that highly viscous materials maintain their structure better, but also have decreased cell viability due to the higher forces which are required for extrusion...
June 20, 2018: Biofabrication
https://www.readbyqxmd.com/read/29922532/the-barrow-biomimetic-spine-comparative-testing-of-a-3d-printed-l4-l5-schwab-grade-2-osteotomy-model-to-a-cadaveric-model
#2
Michael A Bohl, Michael A Mooney, Garrett J Repp, Claudio Cavallo, Peter Nakaji, Steve W Chang, Jay D Turner, U Kumar Kakarla
Introduction The Barrow Biomimetic Spine project is an ongoing effort to develop a three-dimensional (3D)-printed synthetic spine model with high anatomical and biomechanical fidelity to human tissue. The purpose of this study was to evaluate the biomechanical performance of an L4-L5 3D-printed synthetic spine model in a lordotic correction test after Schwab grade 2 osteotomies as compared to human cadaveric spines that have undergone the same osteotomies and lordotic correction. Methods Ten different L4-L5 synthetic spine models were 3D printed...
April 17, 2018: Curēus
https://www.readbyqxmd.com/read/29922020/three-dimensional-printing-in-surgical-planning-a-case-of-aortopulmonary-window-with-interrupted-aortic-arch
#3
Ryan A Moore, William Jack Wallen, Kyle W Riggs, David Ls Morales
Better anatomical understanding and conceptualization of complex congenital heart defects using three-dimensional (3D) printing may improve surgical planning, especially in rare defects. In this report, we utilized 3D printing to delineate the exact cardiac anatomy of a neonate with an aortopulmonary window associated with interrupted aortic arch to devise a novel approach to the repair.
May 2018: Annals of Pediatric Cardiology
https://www.readbyqxmd.com/read/29920790/recent-progress-in-biomimetic-additive-manufacturing-technology-from-materials-to-functional-structures
#4
REVIEW
Yang Yang, Xuan Song, Xiangjia Li, Zeyu Chen, Chi Zhou, Qifa Zhou, Yong Chen
Nature has developed high-performance materials and structures over millions of years of evolution and provides valuable sources of inspiration for the design of next-generation structural materials, given the variety of excellent mechanical, hydrodynamic, optical, and electrical properties. Biomimicry, by learning from nature's concepts and design principles, is driving a paradigm shift in modern materials science and technology. However, the complicated structural architectures in nature far exceed the capability of traditional design and fabrication technologies, which hinders the progress of biomimetic study and its usage in engineering systems...
June 19, 2018: Advanced Materials
https://www.readbyqxmd.com/read/29912877/low-cost-three-dimensional-printed-phantom-for-neuraxial-anesthesia-training-development-and-comparison-to-a-commercial-model
#5
Azad Mashari, Mario Montealegre-Gallegos, Jelliffe Jeganathan, Lu Yeh, Joshua Qua Hiansen, Massimiliano Meineri, Feroze Mahmood, Robina Matyal
METHODS: Anonymized CT DICOM data was segmented to create a 3D model of the lumbar spine. The 3D model was modified, placed inside a digitally designed housing unit and fabricated on a desktop 3D printer using polylactic acid (PLA) filament. The model was filled with an echogenic solution of gelatin with psyllium fiber. Twenty-two staff anesthesiologists performed a spinal and epidural on the 3D printed simulator and a commercially available Simulab phantom. Participants evaluated the tactile and ultrasound imaging fidelity of both phantoms via Likert-scale questionnaire...
2018: PloS One
https://www.readbyqxmd.com/read/29911990/3d-bioprinting-of-scaffolds-with-living-schwann-cells-for-potential-nerve-tissue-engineering-applications
#6
Liqun Ning, Haoying Sun, Tiphanie Lelong, Romain Guilloteau, Ning Zhu, David J Schreyer, Daniel Xiongbiao Chen
Three-dimensional (3D) bioprinting of biomaterials shows great potential for producing cell-encapsulated scaffolds to repair nerves after injury or disease. For this, preparation of biomaterials and bioprinting itself are critical to create scaffolds with both biological and mechanical properties appropriate for nerve regeneration, yet remain unachievable. This paper presents our study on bioprinting Schwann cell-encapsulated scaffolds using composite hydrogels of alginate, fibrin, hyaluronic acid, and/or RGD peptide, for nerve tissue engineering applications...
June 18, 2018: Biofabrication
https://www.readbyqxmd.com/read/29911158/3-d-bioprinting-technologies-in-tissue-engineering-and-regenerative-medicine-current-and-future-trends
#7
Elliot S Bishop, Sami Mostafa, Mikhail Pakvasa, Hue H Luu, Michael J Lee, Jennifer Moriatis Wolf, Guillermo A Ameer, Tong-Chuan He, Russell R Reid
Advances in three-dimensional (3D) printing have increased feasibility towards the synthesis of living tissues. Known as 3D bioprinting, this technology involves the precise layering of cells, biologic scaffolds, and growth factors with the goal of creating bioidentical tissue for a variety of uses. Early successes have demonstrated distinct advantages over conventional tissue engineering strategies. Not surprisingly, there are current challenges to address before 3D bioprinting becomes clinically relevant...
December 2017: Genes & Diseases
https://www.readbyqxmd.com/read/29911125/potential-health-and-environmental-risks-of-three-dimensional-engineered-polymers
#8
Marcia de Almeida Monteiro Melo Ferraz, Heiko H W Henning, Pedro Ferreira da Costa, Jos Malda, Séverine Le Gac, Fabrice Bray, Majorie B M van Duursen, Jos F Brouwers, Chris H A van de Lest, Ingeborg Bertijn, Lisa Kraneburg, Peter L A M Vos, Tom A E Stout, Barend M Gadella
Polymer engineering, such as in three-dimensional (3D) printing, is rapidly gaining popularity, not only in the scientific and medical fields but also in the community in general. However, little is known about the toxicity of engineered materials. Therefore, we assessed the toxicity of 3D-printed and molded parts from five different polymers commonly used for prototyping, fabrication of organ-on-a-chip platforms, and medical devices. Toxic effects of PIC100, E-Shell200, E-Shell300, polydimethylsiloxane, and polystyrene (PS) on early bovine embryo development, on the transactivation of estrogen receptors were assessed, and possible polymer-leached components were identified by mass spectrometry...
February 13, 2018: Environmental Science & Technology Letters
https://www.readbyqxmd.com/read/29906220/three-dimensional-printing-of-personalized-nasal-stents-for-patients-with-cleft-lip
#9
Dongyuan Luo, Ting Li, Hongtao Wang, Yiyang Chen
OBJECTIVE: This report describes the design and printing of personalized nasal stents for cleft lip using 3-dimensional (3D) technology. MATERIALS AND METHODS: We used silicone rubber to make the impressions, a 3D laser scanner to obtain 3D data, and Dental SG resin cartridges as printing material. We printed the personalized nasal stents using a photosensitive resin printer. RESULTS: We placed the stents in patients after cleft lip surgery...
January 1, 2018: Cleft Palate-craniofacial Journal
https://www.readbyqxmd.com/read/29905512/cranioplasty-with-a-low-cost-customized-polymethylmethacrylate-implant-using-a-desktop-3d-printer
#10
Jesús A Morales-Gómez, Everardo Garcia-Estrada, Jorge E Leos-Bortoni, Miriam Delgado-Brito, Luis E Flores-Huerta, Adriana A De La Cruz-Arriaga, Luis J Torres-Díaz, Ángel R Martínez-Ponce de León
OBJECTIVE Cranioplasty implants should be widely available, low in cost, and customized or easy to mold during surgery. Although autologous bone remains the first choice for repair, it cannot always be used due to infection, fragmentation, bone resorption, or other causes, which led to use of synthetic alternatives. The most frequently used allogenic material for cranial reconstructions with long-term results is polymethylmethacrylate (PMMA). Three-dimensional printing technology has allowed the production of increasingly popular customized, prefabricated implants...
June 15, 2018: Journal of Neurosurgery
https://www.readbyqxmd.com/read/29904650/data-related-to-the-experimental-design-for-powder-bed-binder-jetting-additive-manufacturing-of-silicone
#11
Farzad Liravi, Mihaela Vlasea
The data included in this article provides additional supporting information on our recent publication (Liravi et al., 2018 [1]) on a novel hybrid additive manufacturing (AM) method for fabrication of three-dimensional (3D) structures from silicone powder. A design of experiments (DoE) study has been carried out to optimize the geometrical fidelity of AM-made parts. This manuscript includes the details of a multi-level factorial DOE and the response optimization results. The variation in the temperature of powder-bed when exposed to heat is plotted as well...
June 2018: Data in Brief
https://www.readbyqxmd.com/read/29903557/3d-volume-rendering-and-3d-printing-additive-manufacturing
#12
REVIEW
Rujuta A Katkar, Robert M Taft, Gerald T Grant
Three-dimensional (3D) volume-rendered images allow 3D insight into the anatomy, facilitating surgical treatment planning and teaching. 3D printing, additive manufacturing, and rapid prototyping techniques are being used with satisfactory accuracy, mostly for diagnosis and surgical planning, followed by direct manufacture of implantable devices. The major limitation is the time and money spent generating 3D objects. Printer type, material, and build thickness are known to influence the accuracy of printed models...
July 2018: Dental Clinics of North America
https://www.readbyqxmd.com/read/29899654/implantation-of-customized-preshaped-implant-for-orbital-fractures-with-the-aid-of-three-dimensional-printing
#13
Sirous Nekooei, Mahsa Sardabi, Mohammad Etezad Razavi, Amirhossein Nekooei, Mohammad Yaser Kiarudi
Orbital floor fractures alone or in conjunction with other facial skeletal fractures are the most commonly encountered midfacial fractures. The technological advances in 3-dimensional (3D) printing allow the physical prototyping of 3D models, so creates an accurate representation of the patient's specific anatomy. A 56-year-old Caucasian man with severe hypoglobus and enophthalmos with an extensive blowout fracture was scheduled for reconstruction. First, 3D physical models were created based on the computed tomography scan datasets from patient...
January 2018: Middle East African Journal of Ophthalmology
https://www.readbyqxmd.com/read/29899476/printing-ferromagnetic-domains-for-untethered-fast-transforming-soft-materials
#14
Yoonho Kim, Hyunwoo Yuk, Ruike Zhao, Shawn A Chester, Xuanhe Zhao
Soft materials capable of transforming between three-dimensional (3D) shapes in response to stimuli such as light, heat, solvent, electric and magnetic fields have applications in diverse areas such as flexible electronics1,2 , soft robotics3,4 and biomedicine5-7 . In particular, magnetic fields offer a safe and effective manipulation method for biomedical applications, which typically require remote actuation in enclosed and confined spaces8-10 . With advances in magnetic field control 11 , magnetically responsive soft materials have also evolved from embedding discrete magnets 12 or incorporating magnetic particles 13 into soft compounds to generating nonuniform magnetization profiles in polymeric sheets14,15 ...
June 2018: Nature
https://www.readbyqxmd.com/read/29899352/optimisation-of-substrate-angles-for-multi-material-and-multi-functional-inkjet-printing
#15
Jayasheelan Vaithilingam, Ehab Saleh, Ricky D Wildman, Richard J M Hague, Christopher J Tuck
Three dimensional inkjet printing of multiple materials for electronics applications are challenging due to the limited material availability, inconsistencies in layer thickness between dissimilar materials and the need to expose the printed tracks of metal nanoparticles to temperature above 100 °C for sintering. It is envisaged that instead of printing a dielectric and a conductive material on the same plane, by printing conductive tracks on an angled dielectric surface, the required number of silver layers and consequently, the exposure of the polymer to high temperature and the build time of the component can be significantly reduced...
June 13, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29899162/scaling-in-biomechanical-experimentation-a-finite-similitude-approach
#16
Raul Ochoa-Cabrero, Teresa Alonso-Rasgado, Keith Davey
Biological experimentation has many obstacles: resource limitations, unavailability of materials, manufacturing complexities and ethical compliance issues; any approach that resolves all or some of these is of some interest. The aim of this study is applying the recently discovered concept of finite similitude as a novel approach for the design of scaled biomechanical experiments supported with analysis using a commercial finite-element package and validated by means of image correlation software. The study of isotropic scaling of synthetic bones leads to the selection of three-dimensional (3D) printed materials for the trial-space materials...
June 2018: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/29898016/early-assessment-of-right-ventricular-function-in-systemic-lupus-erythematosus-patients-using-strain-and-strain-rate-imaging
#17
Runlan Luo, Hongyan Cui, Dongmei Huang, Lihua Sun, Shengda Song, Mengyao Sun, Guangsen Li
BACKGROUND: Right ventricular function is a crucial factor of the prognosis of systemic lupus erythematosus (SLE). OBJECTIVES: To evaluate the right ventricular function in SLE patients with different degrees of pulmonary hypertension (PH) by strain and strain rate imaging. METHODS: A total of 102 SLE patients and 30 healthy volunteers were studied between October 2015 and May 2016. Patients were divided into three groups according to pulmonary artery systolic pressure (PASP) estimated by echocardiography: group control (A); PASP ≤ 30 mmHg (group B, n = 37); PASP 30-50 mmHg (mild PH; group C, n = 34); and PASP ≥ 50 mmHg (moderate-to-severe PH; group D, n = 31)...
June 11, 2018: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/29897667/transcatheter-closure-of-a-sinus-venosus-atrial-septal-defect-using-3d-printing-and-image-fusion-guidance
#18
Akanksha N Thakkar, Ponraj Chinnadurai, John P Breinholt, C Huie Lin
A 63-year-old man with cirrhosis, hepatocellular carcinoma, and coagulopathy was diagnosed with a sinus venosus atrial septal defect (ASD) and partial anomalous pulmonary venous return (PAPVR) of the right upper pulmonary vein (RUPV). Transcatheter repair by positioning a stent graft in the superior vena cava was planned. Based on three-dimensional (3D) reconstruction of gated cardiac CTA, a 28 mm × 7 cm Endurant II® aortic extension stent graft (Medtronic, MN) was chosen. A 3D model printed from the CTA was used to simulate device deployment, demonstrating successful exclusion of the sinus venosus ASD with return of the RUPV to the left atrium (LA)...
June 13, 2018: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29897358/additive-manufacturing-of-three-dimensional-3d-microfluidic-based-microelectromechanical-systems-mems-for-acoustofluidic-applications
#19
Ellen Cesewski, Alexander P Haring, Yuxin Tong, Manjot Singh, Rajan Thakur, Sahil Laheri, Kaitlin A Read, Michael D Powell, Kenneth J Oestreich, Blake N Johnson
Three-dimensional (3D) printing now enables the fabrication of 3D structural electronics and microfluidics. Further, conventional subtractive manufacturing processes for microelectromechanical systems (MEMS) relatively limit device structure to two dimensions and require post-processing steps for interface with microfluidics. Thus, the objective of this work is to create an additive manufacturing approach for fabrication of 3D microfluidic-based MEMS devices that enables 3D configurations of electromechanical systems and simultaneous integration of microfluidics...
June 13, 2018: Lab on a Chip
https://www.readbyqxmd.com/read/29895208/a-novel-microplate-3d-bioprinting-platform-for-the-engineering-of-muscle-and-tendon-tissues
#20
Sandra Laternser, Hansjoerg Keller, Olivier Leupin, Martin Rausch, Ursula Graf-Hausner, Markus Rimann
Two-dimensional (2D) cell cultures do not reflect the in vivo situation, and thus it is important to develop predictive three-dimensional (3D) in vitro models with enhanced reliability and robustness for drug screening applications. Treatments against muscle-related diseases are becoming more prominent due to the growth of the aging population worldwide. In this study, we describe a novel drug screening platform with automated production of 3D musculoskeletal-tendon-like tissues. With 3D bioprinting, alternating layers of photo-polymerized gelatin-methacryloyl-based bioink and cell suspension tissue models were produced in a dumbbell shape onto novel postholder cell culture inserts in 24-well plates...
June 1, 2018: SLAS Technology
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