keyword
MENU ▼
Read by QxMD icon Read
search

new psychoactive substances (NPS)

keyword
https://www.readbyqxmd.com/read/28088088/prevalence-of-new-psychoactive-substances-in-northeast-asia-from-2007-to-2015
#1
Junhui Lee, Songhee Yang, Yujin Kang, Eunyoung Han, Ling-Yi Feng, Jih-Heng Li, Heesun Chung
The proliferation of new psychoactive substances (NPS) has been a global trend in drug abuse and its regulation has been a worldwide concern. There is no doubt that it is necessary to share information related to these emerging substances between countries and continents for the effective regulation of NPS. With efforts for the efficient regulation of NPS, many studies and information have been published for the prevalence of NPS in the United States and other countries in Europe and Oceania. However, there is lack of information available for the prevalence of NPS in Asian and African countries...
October 20, 2016: Forensic Science International
https://www.readbyqxmd.com/read/28088044/dried-haematic-microsamples-and-lc-ms-ms-for-the-analysis-of-natural-and-synthetic-cannabinoids
#2
Michele Protti, James Rudge, Angelo Eliseo Sberna, Gilberto Gerra, Laura Mercolini
Synthetic cannabinoids are new psychoactive substances (NPS) with similar effects when compared to natural ones found in Cannabis derivatives. They have rapidly integrated into the illicit market, often sold as alternatives under international control. The need to identify and quantify an unprecedented and growing number of new compounds represents a unique challenge for toxicological, forensic and anti-doping analysis. Dried blood spots have been used within the bioanalytical framework in place of plasma or serum, in order to reduce invasiveness, lower sample size, simplify handling, storage and shipping of samples and to facilitate home-based and on-field applications...
December 30, 2016: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28076838/identification-of-mdmb-fubinaca-in-commercially-available-e-liquid-formulations-sold-for-use-in-electronic-cigarettes
#3
Michelle R Peace, Rose I Krakowiak, Carl E Wolf, Alphonse Poklis, Justin L Poklis
MDMB-FUBINACA (aka MDMB(N)-Bz-F), chemical name Methyl (S)-2-(1-(4-fluorobenzyl)-1H-indazole-3-carboxamido)-3,3-dimethylbutanoate, a designer drug or a new psychoactive substance (NPS), was identified in three commercially available e-liquids formulated for electronic cigarette use. The e-liquids were evaluated using direct analysis in real time ion source attached to a time of flight mass spectrometer (DART-MS) and gas chromatograph mass spectrometer (GC-MS) to identify active ingredients/drugs, flavorants, and other possible constituents...
December 27, 2016: Forensic Science International
https://www.readbyqxmd.com/read/28057371/3-meo-pcp-intoxication-in-two-young-men-first-in-vivo-detection-in-italy
#4
Elisabetta Bertol, Jennifer Pascali, Diego Palumbo, Valeria Catalani, Maria Grazia Di Milia, Alessia Fioravanti, Francesco Mari, Fabio Vaiano
3-MeO-PCP or 3-methoxyphencyclidine is a derivative of phencyclidine. It acts as a dissociative anesthetic and it has allegedly hallucinogenic and sedative effects. There are almost no documented intoxication cases and references about its pharmacology and toxicity in literature. This study presents two concomitant intoxication cases due to consumption of 3-MeO-PCP and alcohol. A 19 (A) and a 21 years old (B) men were brought to Santa Maria Nuova Hospital in a comatose state (Glasgow score 3). They showed respiratory acidosis, right anisocoria with mydriatic pupils and hypothermia...
December 26, 2016: Forensic Science International
https://www.readbyqxmd.com/read/28035764/alpha-pvp-as-an-active-component-of-herbal-highs-in-poland-between-2013-2015
#5
Bogumiła Byrska, Roman Stanaszek, Dariusz Zuba
Alpha-PVP (alpha-pyrrolidinovalerophenone, α-PVP) is a synthetic derivative of cathinone. It has been one of the most frequently detected new psychoactive substances (NPS) available on the drug market in recent years in Poland. The usual routes of administration of the drug include oral, insufflation, injection. Unexpectedly, we dealt with a great number of herbal samples that turned out to contain α-PVP. A total number of 352 herbal samples from 19 cases, in which we detected synthetic cathinones, were investigated in the Institute of Forensic Research (IFR) from 2013 to 2015...
December 30, 2016: Drug Testing and Analysis
https://www.readbyqxmd.com/read/28027812/new-psychoactive-substances-nps-on-cryptomarket-fora-an-exploratory-study-of-characteristics-of-forum-activity-between-nps-buyers-and-vendors
#6
Marie Claire Van Hout, Evelyn Hearne
BACKGROUND: The continual diversification of new psychoactive substances (NPS) circumventing legislation creates a public health and law enforcement challenge, and one particularly challenged by availability on Hidden Web cryptomarkets. METHODS: This is the first study of its kind which aimed to explore and characterise cryptomarket forum members' views and perspectives on NPS vendors and products within the context of Hidden Web community dynamics. An internal site search was conducted on two cryptomarkets popular with NPS vendors and hosting fora; Alphabay and Valhalla, using the search terms of 40 popular NPS in the seven categories of stimulant/cathinone; GABA activating; hallucinogen, dissociative, cannabinoid, opioid and other/unspecified/uncategorised NPS...
December 24, 2016: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28025810/application-of-a-combined-approach-to-identify-new-psychoactive-street-drugs-and-decipher-their-mechanisms-at-monoamine-transporters
#7
Felix P Mayer, Anton Luf, Constanze Nagy, Marion Holy, Rainer Schmid, Michael Freissmuth, Harald H Sitte
Psychoactive compounds can cause acute and long-term health problems and lead to addiction. In addition to well-studied and legally controlled compounds like cocaine, new psychoactive substances (NPS) are appearing in street drug markets as replacement strategies and legal alternatives. NPS are effectively marketed as "designer drugs" or "research chemicals" without any knowledge of their underlying pharmacological mode of action and their potential toxicological effects and obviously devoid of any registration process...
December 27, 2016: Current Topics in Behavioral Neurosciences
https://www.readbyqxmd.com/read/28024169/evaluation-of-kims-immunoassays-on-a-cobas-c-501-analyzer-for-drugs-of-abuse-and-ethyl-glucuronide-testing-in-urine-for-forensic-abstinence-control
#8
Merja A Neukamm, Arsham Bahrami, Volker Auwärter, Felix M P Mehne, Eva Höss
For the medico-psychological assessment (MPA) during driving license re-granting in Germany, abstinence control including urine samples is required. In these programs, even small amounts of markers for drug or alcohol abuse have to be detected. Thus, the concentrations of the target compounds are very low, and, in consequence, the sensitivity of the applied screening method has to be much higher than for clinical use. Modified drugs of abuse and ethyl glucuronide immunoassays on a Roche cobas c 501 analyzer were evaluated for precision, accuracy, onboard calibration stability, cross reactivity, sensitivity and specificity using authentic urine samples...
December 26, 2016: Drug Testing and Analysis
https://www.readbyqxmd.com/read/28012094/clinical-pharmacology-of-the-synthetic-cathinone-mephedrone
#9
Esther Papaseit, José Moltó, Robert Muga, Marta Torrens, Rafael de la Torre, Magí Farré
4-Methyl-N-methylcathinone (mephedrone) is a popular new psychoactive substance (NPS) that is structurally related to the parent compound cathinone, the β-keto analogue of amphetamine. Mephedrone appeared on the street drug market as a substitute for 3,4-methylenedioxy-N-methylamphetamine (MDMA, ecstasy) and was subsequently banned due to the potential health risks associated with its use. Nevertheless, mephedrone continues to be widely consumed among specific populations, with unique patterns of misuse. To date, most information about the biological effects of mephedrone comes from user experiences, epidemiological data, clinical cases, toxicological findings, and animal studies, whilst there are very few data regarding its human pharmacodynamics and pharmacokinetics...
December 24, 2016: Current Topics in Behavioral Neurosciences
https://www.readbyqxmd.com/read/28010181/-someone-else-s-problem-new-psychoactive-substances-in-the-online-hungarian-media
#10
Szilvia Kassai, József Rácz, Alexandra Nagy, Tamás Bíbók, Éva Galambvári, Csillag Kilián, V Anna Gyarmathy
Media monitoring is an important method to inform public health and prevention services about emerging health issues, such as new psychoactive substances (NPS). This study assessed the portrayal of NPS in online Hungarian media in 2015 using qualitative content analysis. Hungarian online media considers the dealer to be the main cause of drug use, which is portrayed as a problem for youth, poor people, minorities, and rural populations. The point of view of the articles is externalized, and so is the solution offered by them...
December 23, 2016: Journal of Psychoactive Drugs
https://www.readbyqxmd.com/read/28005158/development-of-a-gc-apci-qtofms-library-for-new-psychoactive-substances-and-comparison-to-a-commercial-esi-library
#11
Samuel Mesihää, Raimo A Ketola, Anna Pelander, Ilpo Rasanen, Ilkka Ojanperä
Gas chromatography coupled to atmospheric pressure chemical ionization quadrupole time-of-flight mass spectrometry (GC-APCI-QTOFMS) was evaluated for the identification of new psychoactive substances (NPS). An in-house high mass resolution GC-APCI-QTOFMS test library was developed for 29 nitrogen-containing drugs belonging mostly to synthetic stimulants. The library was based on 12 intra-day measurements of each compound at three different collision energies, 10, 20 and 40 eV. The in-house library mass spectra were compared to mass spectra from a commercial library constructed by liquid chromatography-electrospray ionization (LC-ESI) QTOFMS...
December 22, 2016: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28000553/new-psychoactive-substances-nps-a-new-global-issue-neuropharmacological-chemical-and-toxicological-aspects
#12
Simona Pichini, Francesco P Busardo, Roberta Pacifici, Pascal Kintz
No abstract text is available yet for this article.
December 20, 2016: Current Neuropharmacology
https://www.readbyqxmd.com/read/27984762/hcv-prevalence-and-risk-behaviours-among-injectors-of-new-psychoactive-substances-in-a-risk-environment-in-hungary-an-expanding-public-health-burden
#13
Anna Tarján, Mária Dudás, Lucas Wiessing, Gergely Horváth, Erzsébet Rusvai, Bálint Tresó, Ágnes Csohán
BACKGROUND: In Hungary a large increase in injecting new psychoactive substances (NPS) coincided with decreasing harm reduction efforts and rising HCV infection. We describe these, and assess changes in HCV prevalence and risk behaviours, 2011-2014, among NPS injectors, using 2011-2015 syringe exchange programme (SEP) data as a key contextual ('risk environment') variable. METHODS: We conducted repeated national sero-behavioural surveys in people who inject drugs (PWID) injecting in the last month and attending SEPs or drug treatment centres (n=399, 2011; 384, 2014), using face-to-face interviews and dried blood-spot samples...
December 13, 2016: International Journal on Drug Policy
https://www.readbyqxmd.com/read/27976363/acute-skin-and-hair-symptoms-followed-by-severe-delayed-eye-complications-in-subjects-using-the-synthetic-opioid-mt-45
#14
A Helander, M Bradley, A Hasselblad, L Norlén, I Vassilaki, M Bäckberg, J Lapins
BACKGROUND: The introduction of unclassified new psychoactive substances (NPS) on the recreational drugs market through open online sale ('legal highs' or 'Internet drugs') continues unabated and represents a growing health hazard. The use of NPS has resulted in numerous, severe, adverse events and fatalities, due to unintended overdose or unknown toxic side-effects. OBJECTIVES: To try to find a possible common underlying cause for the skin-hair-eye symptoms complex observed in three men...
December 14, 2016: British Journal of Dermatology
https://www.readbyqxmd.com/read/27956185/assessing-the-added-value-of-european-policy-on-new-psychoactive-substances
#15
Caroline Chatwin
BACKGROUND: New psychoactive substances (NPS) are reported to be on the rise throughout Europe, and are often presented as the latest challenge facing drug-policy makers. At the European level, legislation on NPS has existed since 1998. Several evaluations, however, have suggested that this legislation is not effective and the European Commission has submitted a new proposal on NPS seeking to extend its powers in this area. METHODS: This article critically evaluates the new proposal against its predecessor's three main criticisms: (i) being unable to tackle the large number of NPS because of lengthy European legislative approaches, (ii) being reactive rather than proactive, and (iii) lacking options for regulatory and control measures...
December 9, 2016: International Journal on Drug Policy
https://www.readbyqxmd.com/read/27956184/new-psychoactive-substances-current-health-related-practices-and-challenges-in-responding-to-use-and-harms-in-europe
#16
Alessandro Pirona, Alessandra Bo, Dagmar Hedrich, Marica Ferri, Nadine van Gelder, Isabelle Giraudon, Linda Montanari, Roland Simon, Jane Mounteney
BACKGROUND: The availability of new psychoactive substances (NPS) in Europe has rapidly increased over the last decade. Although prevalence levels of NPS use remain low in the general European population, there are serious concerns associated with more problematic forms of use and harms in particular populations and settings. It has thus become a priority to formulate and implement effective public health responses. However, considerable knowledge gaps remain on current practices as well as on the challenges and needs of European health professionals who are responding to use and harms caused by these substances...
December 9, 2016: International Journal on Drug Policy
https://www.readbyqxmd.com/read/27955961/adding-spice-to-the-porridge-the-development-of-a-synthetic-cannabinoid-market-in-an-english-prison
#17
Rob Ralphs, Lisa Williams, Rebecca Askew, Anna Norton
BACKGROUND: In 2014, the annual report of the Her Majesty's Chief Inspector of Prisons (HMIP) for England and Wales raised concerns regarding New Psychoactive Substance (NPS) use in custody, specifically the consumption of synthetic cannabinoids. To date, however, the use of these substances in prison populations, and the markets that have emerged to facilitate it, have been under-researched. METHODS: Our research was conducted in an English adult male prison using multi-method techniques...
December 7, 2016: International Journal on Drug Policy
https://www.readbyqxmd.com/read/27939599/i-like-the-old-stuff-better-than-the-new-stuff-subjective-experiences-of-new-psychoactive-substances
#18
Allison Matthews, Rachel Sutherland, Amy Peacock, Joe Van Buskirk, Elizabeth Whittaker, Lucinda Burns, Raimondo Bruno
BACKGROUND: Over the past decade, monitoring systems have identified the rapid emergence of new psychoactive substances (NPS). While the use of many NPS is minimal and transitory, little is known about which products have potential for capturing the attention of significant proportions of the drug consuming market. The aim of this study was to explore self-reported experiences of three commonly used NPS classes within the Australian context (synthetic cathinones, hallucinogenic phenethylamines and hallucinogenic tryptamines) relative to traditional illicit drug counterparts...
December 8, 2016: International Journal on Drug Policy
https://www.readbyqxmd.com/read/27939297/health-and-social-care-workers-perceptions-of-nps-use-in-northern-ireland
#19
Anne Campbell, Nina O Neill, Kathryn Higgins
BACKGROUND: The EU Early Warning System currently monitors more than 560 new psychoactive substances, far outweighing the total number of illicit drugs under international control. Due to the recent emergence of NPS and rapidly changing nature of the market, evidence about the way in which the emerging drugs are managed in health and social care settings is limited. METHODS: The study adopted a mixed methods design, utilising a cross sectional survey and telephone interviews to capture data from staff working in drug and alcohol related services in statutory and voluntary sectors, across the five Health and Social Care (HSC) Trust areas in Northern Ireland...
December 6, 2016: International Journal on Drug Policy
https://www.readbyqxmd.com/read/27936283/purity-adulteration-and-price-of-drugs-bought-online-versus-offline-in-the-netherlands
#20
Daan van der Gouwe, Tibor M Brunt, Margriet van Laar, Peggy van der Pol
BACKGROUND AND AIMS: Online drug markets flourish and consumers have high expectations of online quality and drug value. The aim of this study was to i) describe online drug purchases, and ii) compare online with offline purchased drugs regarding purity, adulteration and price. DESIGN: Comparison of lab analyses of 32,663 drug consumer samples (stimulants and hallucinogens) purchased between January 2013 and January 2016, of which 928 were bought online. SETTING: The Netherlands...
December 9, 2016: Addiction
keyword
keyword
76326
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"