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https://www.readbyqxmd.com/read/27920760/prevalence-of-the-antibiotic-resistance-genes-in-coagulase-positive-and-negative-staphylococcus-in-chicken-meat-retailed-to-consumers
#1
Kamelia Osman, Jihan Badr, Khalid S Al-Maary, Ihab M I Moussa, Ashgan M Hessain, Zeinab M S Amin Girah, Usama H Abo-Shama, Ahmed Orabi, Aalaa Saad
The use of antibiotics in farm management (growing crops and raising animals) has become a major area of concern. Its implications is the consequent emergence of antibiotic resistant bacteria (ARB) and accordingly their access into the human food chain with passage of antibiotic resistance genes (ARG) to the normal human intestinal microbiota and hence to other pathogenic bacteria causative human disease. Therefore, we pursued in this study to unravel the frequency and the quinolone resistance determining region, mecA and cfr genes of methicillin-susceptible Staphylococcus aureus (MSSA), methicillin-resistant S...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27899322/a-randomized-controlled-trial-of-prophylactic-antibiotics-in-the-prevention-of-electrocoagulation-syndrome-after-colorectal-endoscopic-submucosal-dissection
#2
Sang Pyo Lee, In-Kyung Sung, Jeong Hwan Kim, Sun-Young Lee, Hyung Seok Park, Chan Sup Shim, Hyun Kyun Ki
BACKGROUND AND AIMS: Endoscopic submucosal dissection (ESD) is currently commonly performed, but colorectal ESD has a substantial risk of adverse events, including post-ESD electrocoagulation syndrome (PEECS). We investigated whether the use of prophylactic antibiotics can reduce the occurrence of PEECS. METHODS: Patients who underwent colorectal ESD were randomly assigned to 1 of 2 treatment regimens. Ampicillin/sulbactam mixed with normal saline solution was administered 1 hour before ESD in group I, and then additionally injected every 8 hours twice more...
November 26, 2016: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/27895902/effect-of-%C3%AE-lactamase-inhibitors-on-in-vitro-activity-of-%C3%AE-lactam-antibiotics-against-burkholderia-cepacia-complex-species
#3
Annelien Everaert, Tom Coenye
BACKGROUND: Bacteria belonging to the Burkholderia cepacia complex (Bcc) are an important cause of chronic respiratory tract infections in cystic fibrosis patients. Intrinsic resistance to a wide range of antimicrobial agents, including a variety of β-lactam antibiotics, is frequently observed in Bcc strains. Resistance to β-lactams is most commonly mediated by efflux pumps, alterations in penicillin-binding proteins or the expression of β-lactamases. β-lactamase inhibitors are able to restore the in vitro activity of β-lactam molecules against a variety of Gram-negative species, but the effect of these inhibitors on the activity of β-lactam treatment against Bcc species is still poorly investigated...
2016: Antimicrobial Resistance and Infection Control
https://www.readbyqxmd.com/read/27891373/retrospective-comparison-of-clinical-characteristics-and-in-hospital-outcomes-among-diabetic-and-non-diabetic-adults-with-acute-pyelonephritis
#4
Shailesh C Trivedi, Sanjeev R Phatak, Renu S Trivedi
INTRODUCTION: Acute Pyelonephritis (APN) is a common infection in community. Diabetes Mellitus (DM) may have different effect on clinical characteristics and outcomes of APN compared to non-diabetic individuals. AIM: To compare clinical characteristics and assess outcomes of APN patients with and without DM. MATERIALS AND METHODS: A retrospective analysis of 122 patients with DM (n=61) and without DM (n=61) was conducted at a single, private, urban set-up from Gujarat, India...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27881972/multilocus-sequence-typing-analysis-of-carbapenem-resistant-acinetobacter-baumannii-in-a-chinese-burns-institute
#5
Guangtao Huang, Supeng Yin, Yali Gong, Xia Zhao, Lingyun Zou, Bei Jiang, Zhiwei Dong, Yu Chen, Jing Chen, Shouguang Jin, Zhiqiang Yuan, Yizhi Peng
Acinetobacter baumannii is a leading pathogen responsible for nosocomial infections. The emergence of carbapenem-resistant A. baumannii (CRAB) has left few effective antibiotics for clinicians to use. To investigate the temporal evolutionary relationships among CRAB strains, we collected 248 CRAB isolates from a Chinese burns institute over 3 years. The prevalence of the OXA-23 gene was detected by polymerase chain reaction. Multilocus sequence typing was used to type the CRAB strains and eBURST was used to analyze their evolutionary relationships...
2016: Frontiers in Microbiology
https://www.readbyqxmd.com/read/27867083/trends-in-antimicrobial-resistance-among-bacteroides-species-and-parabacteroides-species-in-the-united-states-from-2010-2012-with-comparison-to-2008-2009
#6
REVIEW
D R Snydman, N V Jacobus, L A McDermott, E J C Goldstein, L Harrell, S G Jenkins, D Newton, R Patel, D W Hecht
The susceptibility trends for Bacteroides fragilis and related species against various antibiotics were determined using data from 3 years of surveillance (2010-2012) on 779 isolates referred by 7 medical centers. The antibiotic test panel included imipenem, ertapenem, meropenem, ampicillin-sulbactam, piperacillin-tazobactam, cefoxitin, clindamycin, moxifloxacin, tigecycline, linezolid, chloramphenicol and . MICs were determined using the agar dilution CLSI reference method. Carbapenem resistance remained low (range 1...
November 17, 2016: Anaerobe
https://www.readbyqxmd.com/read/27830081/inhibitory-effect-of-lactobacillus-plantarum-and-lb-fermentum-isolated-from-the-faeces-of-healthy-infants-against-nonfermentative-bacteria-causing-nosocomial-infections
#7
M M Soltan Dallal, A Davoodabadi, M Abdi, M Hajiabdolbaghi, M K Sharifi Yazdi, M Douraghi, S M Tabatabaei Bafghi
Nosocomial infection constitutes a major public health problem worldwide. Increasing antibiotic resistance of pathogens associated with nosocomial infections has also become a major therapeutic challenge for physicians. Thus, development of alternative treatment protocols, such as the use of probiotics, matters. The aim of this research was to determine the antagonistic properties of Lactobacillus plantarum and Lb. fermentum isolated from the faeces of healthy infants against nonfermentative bacteria causing nosocomial infections...
January 2017: New Microbes and New Infections
https://www.readbyqxmd.com/read/27825282/relationship-between-maternal-c-reactive-protein-level-and-neonatal-outcome-in-patients-with-preterm-premature-rupture-of-membranes-treated-with-ampicillin-and-azithromycin
#8
Mehmet Serdar Kutuk, Osman Bastug, Ahmet Ozdemir, Mehmet Adnan Ozturk, Mahmut Tuncay Ozgun, Mustafa Basbug, Tamer Gunes, Selim Kurtoglu
This historical cohort study aimed to assess the relationship between antenatal maternal C-reactive protein (CRP) level and neonatal outcome preterm premature rupture of membranes (PPROM). We reviewed the records of 70 singleton pregnancies with PPROM between 24 and 34 weeks. Maternal CRP levels of neonates with respiratory distress syndrome, neonatal sepsis, grade 3-4 intraventricular haemorrhage and stage 2-3 necrotizing enterocolitis, perinatal mortality were compared with those without these complications...
August 2016: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/27822762/clinical-practice-audit-concerning-antimicrobial-prophylaxis-in-paediatric-neurosurgery-results-from-a-german-paediatric-oncology-unit
#9
Katja Weiss, Arne Simon, Norbert Graf, Jakob Schöpe, Joachim Oertel, Stefan Linsler
BACKGROUND: Perioperative antimicrobial prophylaxis (PAP) has been identified as an important target for internal audits, concerning the judicious use of antibiotics. Paediatric oncology patients with brain tumours face an increased risk of surgical site infection (SSI) after neurosurgery and receive routine PAP in this setting. PATIENTS AND METHODS: All patients younger than 18 years admitted to the paediatric oncology centre (POC) with a neurosurgical intervention...
November 7, 2016: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/27821452/ctx-m-190-a-novel-%C3%AE-lactamase-resistant-to-tazobactam-and-sulbactam-identified-in-an-escherichia-coli-clinical-isolate
#10
Zhen Shen, Baixing Ding, Yingmin Bi, Shi Wu, Su Xu, Xiaogang Xu, Qinglan Guo, Minggui Wang
A novel β-lactamase CTX-M-190, derived from CTX-M-55 by a single substitution Ser133Thr, was identified in a natural Escherichia coli clinical isolate. CTX-M-190 exhibited potent hydrolytic activity against cefotaxime with kcat/Km 14.5 μM(-1) s(-1) and was resistant to inhibition by β-lactamase inhibitors tazobactam and sulbactam with the 50% inhibitory concentrations 77- and 55-fold higher than those of CTX-M-55, respectively. blaCTX-M-190 was located within the genetic platform, ISEcp1-blaCTX-M-orf477, which was harbored by a 70kb IncI1 plasmid...
November 7, 2016: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/27821441/beta-lactamase-inhibitors-enhance-the-synergy-between-beta-lactam-antibiotics-and-daptomycin-against-methicillin-resistant-staphylococcus-aureus
#11
Karl Evans R Henson, Juwon Yim, Jordan R Smith, George Sakoulas, Michael J Rybak
The evidence for using combination therapy for the treatment of serious methicillin-resistant Staphylococcus aureus (MRSA) infections is growing. In this study, we investigate the synergistic effect of daptomycin combined with piperacillin+tazobactam and ampicillin+sulbactam against MRSA using time-kill experiments. Six of 8 strains demonstrated synergy between DAP and the β-lactam/β-lactamase inhibitor (BLI) combination. In 5/8 strains, the synergy occurred only in the presence of the BLI, highlighting a role for BLIs in peptide-beta-lactam synergy...
November 7, 2016: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/27800254/canaliculitis-awareness
#12
Melike Balıkoğlu Yılmaz, Emine Şen, Ebru Evren, Ufuk Elgin, Pelin Yılmazbaş
OBJECTIVES: To evaluate the demographic characteristics, treatment, and results of patients with canaliculitis. MATERIALS AND METHODS: Medical records including the demographic characteristics, clinical findings, and treatment outcomes of patients diagnosed and treated for canaliculitis between September 2009 and March 2014 were analyzed retrospectively. RESULTS: The median age of the 7 canaliculitis patients consisting of 4 women and 3 men was 49 (range 8-58) years...
January 2016: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/27769572/susceptibility-to-penicillin-derivatives-among-third-generation-cephalosporin-resistant-enterobacteriaceae-recovered-on-hospital-admission
#13
Alexander Mischnik, Philipp Baumert, Axel Hamprecht, Anna Rohde, Silke Peter, Susanne Feihl, Johannes Knobloch, Hanna Gölz, Axel Kola, Birgit Obermann, Christiane Querbach, Matthias Willmann, Friedemann Gebhardt, Evelina Tacconelli, Petra Gastmeier, Harald Seifert, Winfried V Kern
As part of the multicenter Antibiotic Therapy Optimisation Study-the largest study on the prevalence of third-generation cephalosporin-resistant Enterobacteriaceae carriage upon hospital admission-minimum inhibitory concentration values were generated for ampicillin/sulbactam, amoxicillin/clavulanic acid, piperacillin/tazobactam, mecillinam, mecillinam/clavulanic acid, and temocillin against third-generation cephalosporin-resistant Escherichia coli, Klebsiella species and Enterobacter species.
September 23, 2016: Diagnostic Microbiology and Infectious Disease
https://www.readbyqxmd.com/read/27766023/lower-body-mass-index-is-a-risk-factor-for-in-hospital-mortality-of-elderly-japanese-patients-treated-with-ampicillin-sulbactam
#14
Makoto Miura, Akiko Kuwahara, Akinori Tomozawa, Naoki Omae, Motohiro Yamamori, Kaori Kadoyama, Toshiyuki Sakaeda
Objectives: A retrospective examination was conducted to identify risk factors for in-hospital mortality of elderly patients (65 years or older) treated with the beta-lactam/beta-lactamase inhibitor combination antibiotic, ampicillin/sulbactam (ABPC/SBT). Methods: Clinical data from 96 patients who were hospitalized with infectious diseases and treated with ABPC/SBT (9 g/day or 12 g/day) were analyzed. Risk factors examined included demographic and clinical laboratory parameters. Parameter values prior to treatment and changes after treatment were compared between survivors and non-survivors...
2016: International Journal of Medical Sciences
https://www.readbyqxmd.com/read/27751220/-effect-of-%C3%AE-lactamase-detection-on-reducing-the-incidence-of-antibiotic-associated-diarrhea-in-children-with-severe-bacterial-pneumonia
#15
Yun Xiang, Zai-Hua Wang, Ping Cai, Zhen Zhang
OBJECTIVE: To study the effect of β-lactamase (BLs) detection and β-lactam/β-lactamase inhibitor (BL/BLI) on the incidence of antibiotic-associated diarrhea (AAD) in children with severe bacterial pneumonia. METHODS: The clinical data of the children with bacterial severe pneumonia were retrospectively studied. Of all the patients, 248 using amoxicillin/clavulanate but without BLs detection and 323 using amoxicillin (BLs negative) or amoxicillin/clavulanate (BLs positive) were used as the amoxicillin group; 208 patients using piperacillin/tazobactam but without BLs detection and 291 patients using piperacillin (BLs negative) or piperacillin/tazobactam (BLs positive) were used as the piperacillin group; and 191 patients using cefoperazone/sulbactam but without BLs detection and 341 patients using cefoperazone (BLs negative) or cefoperazone/sulbactam (BLs positive) were used as the cefoperazone group...
October 2016: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/27748464/spontaneous-pneumomediastinum-following-pneumonia-in-a-23-year-old-male-patient
#16
Yusuf Kayar, Nüket Bayram Kayar, Tuncay Şahutoğlu, Venkatanarayana Gangarapu
Spontaneous pneumomediastinum (SPM) is defined as the presence of interstitial air in the mediastinum without any apparent precipitating factor. We present a case of 23 year old male patient, who has been referred to our outpatient clinic with the complaints of sudden chest pain, dyspnea followed by pneumonia and was diagnosed as SPM. The patient was treated with ampicillin sulbactam (4 gr/day) and methylprednisolon (20 mg/day) for 4 days. and oral intake was stopped during treatment. Post treatment, it was observed that the crepitations were disappeared thoroughly and vesicular sounds were heard by oscultation...
October 14, 2016: Monaldi Archives for Chest Disease, Archivio Monaldi Per le Malattie del Torace
https://www.readbyqxmd.com/read/27747682/cefoperazone-sulbactam-induced-abdominal-wall-hematoma-and-upper-gastrointestinal-bleeding-a-case-report-and-review-of-the-literature
#17
ZhuYing Cai, Wei Yang, YingYing He, Qingge Chen, ShiQiang Wang, Xuming Luo, Xiongbiao Wang
An 87-year-old woman developed abdominal wall hematoma and upper gastrointestinal bleeding during treatment with cefoperazone/sulbactam for pneumonia. The woman received cefoperazone/sulbactam at 4.5 g twice daily for intravenous infusion. After 7 days, she developed sudden onset of left lower abdominal pain, associated with subcutaneous mass, and vomited a coffee-colored liquid. Investigations revealed a coagulation index abnormality and activated partial thromboplastin time and prothrombin time increased obviously...
December 2016: Drug Safety—Case Reports
https://www.readbyqxmd.com/read/27745799/bacteria-in-the-apical-root-canals-of-teeth-with-apical-periodontitis
#18
Li-Wan Lee, Ya-Ling Lee, Sheng-Huang Hsiao, Hung-Pin Lin
BACKGROUND/PURPOSE: Bacteria in the tooth root canal may cause apical periodontitis. This study examined the bacterial species present in the apical root canal of teeth with apical periodontitis. Antibiotic sensitivity tests were performed to evaluate whether these identified bacterial species were susceptible to specific kinds of antibiotics. METHODS: Selective media plating and biochemical tests were used first to detect the bacterial species in samples taken from the apical portion of root canals of 62 teeth with apical periodontitis...
October 10, 2016: Journal of the Formosan Medical Association, Taiwan Yi Zhi
https://www.readbyqxmd.com/read/27738486/bacterial-pneumonia-caused-by-streptococcus-pyogenes-infection-a-case-report-and-review-of-the-literature
#19
Nobuhiro Akuzawa, Masahiko Kurabayashi
A 78-year-old Japanese man was admitted to our hospital because of fever lasting for 4 days. His white blood cell count and C-reactive protein level were elevated and computed tomography of the chest showed bronchopneumonia in the right upper lobe of the lung. Streptococcus pyogenes was detected from sputum and blood culture samples on admission and administration of ampicillin/sulbactam was effective. Although our patient's clinical course was good, S. pyogenes pneumonia commonly shows a high rate of fatality and septicemia, and may affect a previously healthy population...
November 2016: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/27735805/the-first-case-of-raoultella-terrigena-infection-in-an-infant
#20
Tayfur Demiray, Mehmet Köroğlu, Ahmet Özbek, Taner Hafizoğlu, Mustafa Altındiş
Raoultella terrigena, formerly known as Klebsiella terrigena is Gram-negative, non-motile, facultative anaerobic, encapsulated bacilli and is a very rare cause of infections in humans. Until now, only two cases of actual clinical infection caused by R. terrigena were reported in adults. This report is the first case of neonatal infection with this microorganism, which was isolated from the urinary tract of a premature newborn followed in Neonatal Intensive Care Unit. Vitek 2® automated system had identified the bacteria as R...
November 2015: Turkish Journal of Pediatrics
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