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https://www.readbyqxmd.com/read/28719512/a-pediatric-case-of-persistent-thrombocytopenia-in-a-patient-who-developed-all
#1
Haroon Shaukat, Jessica O'Mara, Michelle Neier
Inherited thrombocytopenia is a topic that was expanded greatly over the last decade and many new genes are being identified. However, inheritance patterns are not always easy to identify because sporadic cases from de novo mutations may in fact be more common. Few studies have assessed the relationship between thrombocytopenia and malignancies, specifically acute lymphoblastic leukemia (ALL). Here we present a pediatric case of persistent thrombocytopenia associated with T-cell ALL. Our patient was initially diagnosed with immune thrombocytopenic purpura with no evidence of malignancy on bone marrow biopsy but presented shortly after with ALL...
July 17, 2017: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/28714340/statement-of-redundant-publication
#2
(no author information available yet)
For Prathanee B, Thinkhamrop B, Dechongkit S. Factors Associated With Specific Language Impairment and Later Language Development During Early Life: A Literature Review. Clin Pediatr. 2007;46:22-29. This statement has been added based on determining significant overlap with the following article, published earlier, with an authorship including one of the co-authors, Bandit Thinkhamrop: Chaimay B, Thinkhamrop B, Thinkhamrop J. Risk Factors Associated with Language Development Problems in Childhood - A Literature Review...
July 1, 2017: Clinical Pediatrics
https://www.readbyqxmd.com/read/28713146/-being-persistent-without-being-pushy-student-reflections-on-vaccine-hesitancy
#3
Amy E Caruso Brown, Manika Suryadevara, Thomas R Welch, Ann S Botash
Our goal as pediatric educators is to graduate physicians who have witnessed effective approaches and have grasped the nuances of communication strategies between vaccine-hesitant families and health care providers. We identified vaccine hesitancy as a recurring topic in 19 of 304 medical student reflective narratives addressing an issue in professionalism or systems-based practice. We conducted content analysis on the narratives in order to gain a better understanding of student perceptions of visits in which they observed a provider discussing vaccine hesitancy with a parent...
2017: Narrative Inquiry in Bioethics
https://www.readbyqxmd.com/read/28710506/obese-versus-normal-weight-late-adolescent-females-have-inferior-trabecular-bone-microarchitecture-a-pilot-case-control-study
#4
Joseph M Kindler, Norman K Pollock, Hannah L Ross, Christopher M Modlesky, Harshvardhan Singh, Emma M Laing, Richard D Lewis
Though still a topic of debate, the position that skeletal health is compromised with obesity has received support in the pediatric and adult literature. The limited data relating specifically to trabecular bone microarchitecture, however, have been relatively inconsistent. The aim of this pilot cross-sectional case-control study was to compare trabecular bone microarchitecture between obese (OB) and normal-weight (NW) late-adolescent females. A secondary aim was to compare diaphyseal cortical bone outcomes between these two groups...
July 14, 2017: Calcified Tissue International
https://www.readbyqxmd.com/read/28708428/reliability-and-correlation-of-static-and-dynamic-foot-arch-measurement-in-a-healthy-pediatric-population
#5
Karsten Hollander, Timo Scholz, Astrid Zech, Karl Wegscheider, Susanne Lezius, Klaus-Michael Braumann, Susanne Sehner
BACKGROUND: The measurement of the medial longitudinal foot arch in children is a controversial topic, as there are many different methods without a definite gold-standard. The purpose of this study was to 1) investigate intra-day- and inter-rater-reliability regarding dynamic arch index and static arch height, 2) to explore the correlation between both arch indices and 3) to examine the variation of the medial longitudinal arch at two different times of the day. METHODS: Eighty-six children (age 8...
July 14, 2017: Journal of the American Podiatric Medical Association
https://www.readbyqxmd.com/read/28707590/combining-drug-and-psychological-treatments-for-obsessive-compulsive-disorder-what-is-the-evidence-when-and-for-whom
#6
Umberto Albert, Gabriele Di Salvo, Francesca Solia, Gianluca Rosso, Giuseppe Maina
BACKGROUND: serotonin reuptake inhibitors (SRIs) and cognitive-behavioral psychotherapy (CBT) are first-line treatments for obsessive-compulsive disorder (OCD). Since response is often inadequate, in recent years researchers investigated whether combining CBT and SRIs, either ab initio or sequentially, results in a greater reduction of obsessive-compulsive symptoms. OBJECTIVE: the aims of the present paper are to assess if combination treatment seems adding benefits as compared to either monotherapy alone and if sequential strategies may be effective in converting partial or non responders to a first-line treatment into responders...
July 12, 2017: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/28704168/integrating-agricultural-injury-prevention-with-rural-pediatrics-a-pilot-assessment
#7
Julie Kaprelian, Richard L Berg, Kathrine Lynn Barnes, Barbara Marlenga
BACKGROUND: Childhood agricultural injuries are an important public health problem. Pediatricians are a trusted source of expertise in children's health and safety and could serve as a sphere of influence to augment child agricultural injury prevention efforts. The purpose of this pilot study was to begin to explore the perspectives of pediatricians in a large rural health clinic about addressing child agricultural injury prevention within their practice. METHODS: Structured interviews were conducted with nine pediatricians who maintain a clinical practice of at least 2 days a week and care for newborns through adolescents...
July 13, 2017: Journal of Agromedicine
https://www.readbyqxmd.com/read/28704068/breaking-down-barriers-in-pediatric-mental-health-consultations-understanding-patients-use-of-i-don-t-know
#8
Ashley M Hesson, Heike Pichler
Barriers to effective provider-patient communication take many forms that can be difficult to recognize and appropriately address. This paper offers probabilistic indicators for one such form, patient-produced "I don't know" (IDK), distinguishing its use as a cognitive claim and its use as a strategy for resisting discussion of sensitive topics. A total of 95 audio-recorded psychiatrist-child interactions are drawn from a US-wide corpus of physician-patient consultations. From these, 376 patient-produced IDKs are extracted and coded for linguistic/social factors, including form, function, prosody, age, gender, and primary diagnosis...
July 13, 2017: Health Communication
https://www.readbyqxmd.com/read/28699152/-characteristics-of-structural-injuries-in-pediatric-patients-with-focal-epilepsy-in-a-honduran-hospital
#9
A Ramirez-Izcoa, D Varela-Gonzalez, M I Fonseca
INTRODUCTION: Epilepsy is the most commonly occurring neurological disorder in the world. The study of structural brain lesions is important to understand the secondary complications. In Honduras there is little information on this topic. AIM: To determine the characteristics and proportion of structural brain lesions in paediatric patients with focal epilepsy at the Hospital Escuela Universitario. PATIENTS AND METHODS: A descriptive, cross-sectional, retrospective-prospective study...
August 1, 2017: Revista de Neurologia
https://www.readbyqxmd.com/read/28697264/early-adversity-toxic-stress-and-resilience-pediatrics-for-today
#10
M Denise Dowd
Never before in the history of science have we had better insight into the factors that determine the health and well-being of a person from infancy to adulthood. An expanding body of knowledge is converging from numerous disciplines including neuroscience, education, behavioral science, public health, the social sciences, and medicine. Awareness of the impact of early childhood adversity and toxic stress is growing rapidly among both professionals and the lay public. This calls for a reevaluation of how and what we, as child health care providers, should deliver to maximize our impact on individual health and well-being across the lifespan...
July 1, 2017: Pediatric Annals
https://www.readbyqxmd.com/read/28697215/update-on-the-systemic-risks-of-superpotent-topical-steroids
#11
Mio Nakamura, Michael Abrouk, Henry Zhu, Benjamin Farahnik, John Koo, Tina Bhutani
<p>INTRODUCTION: The potential for systemic effects due to percutaneous absorption of superpotent topical steroids has been a longstanding concern. The Food and Drug Administration currently recommends limiting the use of superpotent topical steroids to 50g per week for 2 or 4 consecutive weeks depending on the formulation, which is mostly based on the exact duration with which phase 3 clinical trials were allowed to be conducted per the FDA. This article reviews all published clinical incidence of adrenal adverse effects in the medical literature, specifically Cushing's syndrome (CS) and pathologic adrenal suppression (PAAS), to try to ascertain a more realistic limit for the safe use of superpotent topical steroids as it pertains to its potential systemic effects...
July 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28696955/pediatric-blepharokeratoconjunctivitis-is-there-a-right-treatment
#12
Sepideh T Rousta
PURPOSE OF REVIEW: This article highlights the importance of recognizing blepharokeratoconjunctivitis (BKC) in children and reviews the clinical characteristics and current therapeutic modalities. RECENT FINDINGS: The mainstay of BKC treatment remains controlling the meibomian gland inflammation and treating cobormid conditions. BKC can occur in the setting of ocular rosacea and Demodex infestation. Small studies have shown treatment benefits of topical cyclosporine A as well as oral azithromycin in pediatric BKC...
July 10, 2017: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/28696526/highlights-from-the-2016-north-american-cystic-fibrosis-conference
#13
REVIEW
Edith T Zemanick, Cori L Daines, Elisabeth P Dellon, Charles R Esther, BreAnna Kinghorn, Thida Ong, Marianne S Muhlebach
The 30th annual North American Cystic Fibrosis Conference (NACFC) was held in Orlando, FL, on October 27-29, 2016. Abstracts were published in a supplement to Pediatric Pulmonology. This review summarizes several major topic areas addressed at the conference: the pathophysiology of cystic fibrosis (CF) lung disease, clinical trials, clinical management issues, and quality improvement. We sought to provide an overview of emerging concepts in several areas of CF research and care, rather than a comprehensive review of the conference...
July 11, 2017: Pediatric Pulmonology
https://www.readbyqxmd.com/read/28691236/response-to-vogelstein-how-the-2012-aap-task-force-on-circumcision-went-wrong
#14
Robert S Van Howe
Vogelstein cautions medical organizations against jumping into the fray of controversial issues, yet proffers the 2012 American Academy of Pediatrics' Task Force policy position on infant male circumcision as 'an appropriate use of position-statements.' Only a scratch below the surface of this policy statement uncovers the Task Force's failure to consider Vogelstein's many caveats. The Task Force supported the cultural practice by putting undeserved emphasis on questionable scientific data, while ignoring or underplaying the importance of valid contrary scientific data...
July 9, 2017: Bioethics
https://www.readbyqxmd.com/read/28688664/a-novel-flight-surgeon-training-model-at-a-joint-military-and-civilian-surgical-residency-program
#15
Erik S DeSoucy, Scott A Zakaluzny, Joseph M Galante
BACKGROUND: Graduating military preliminary interns are often required to fill flight surgeon billets. General surgery preliminary interns get experience evaluating surgical and trauma patients, but receive very little training in primary care and flight medicine. At a joint military and civilian training program, we developed a supplemental curriculum to help transition our interns into flight medicine. METHODS: From 2013 to 2016, we developed a lecture series focused on aerospace medicine, primary care, and specialty topics including dermatology, ophthalmology, orthopedics, pediatrics, psychiatry, and women's health...
July 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28688548/eeg-activity-as-an-objective-measure-of-cognitive-load-during-effortful-listening-a-study-on-pediatric-subjects-with-bilateral-asymmetric-sensorineural-hearing-loss
#16
Pasquale Marsella, Alessandro Scorpecci, Giulia Cartocci, Sara Giannantonio, Anton Giulio Maglione, Isotta Venuti, Ambra Brizi, Fabio Babiloni
OBJECTIVES: Deaf subjects with hearing aids or cochlear implants generally find it challenging to understand speech in noisy environments where a great deal of listening effort and cognitive load are invested. In prelingually deaf children, such difficulties may have detrimental consequences on the learning process and, later in life, on academic performance. Despite the importance of such a topic, currently, there is no validated test for the assessment of cognitive load during audiological tasks...
August 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28679656/staphylococcus-aureus-and-staphylococcus-epidermidis-strain-diversity-underlying-pediatric-atopic-dermatitis
#17
Allyson L Byrd, Clay Deming, Sara K B Cassidy, Oliver J Harrison, Weng-Ian Ng, Sean Conlan, Yasmine Belkaid, Julia A Segre, Heidi H Kong
The heterogeneous course, severity, and treatment responses among patients with atopic dermatitis (AD; eczema) highlight the complexity of this multifactorial disease. Prior studies have used traditional typing methods on cultivated isolates or sequenced a bacterial marker gene to study the skin microbial communities of AD patients. Shotgun metagenomic sequence analysis provides much greater resolution, elucidating multiple levels of microbial community assembly ranging from kingdom to species and strain-level diversification...
July 5, 2017: Science Translational Medicine
https://www.readbyqxmd.com/read/28670641/tick-infestation-a-200-patients-series
#18
Oya Guven, Dilay Satilmis, Feruza Turan Sonmez, Bilgehan Demir, Özgür Erdogan
BACKGROUND: A great number of zoonotic diseases with high mortality rate are transmitted by ticks. We performed this study in order to investigate patients admitted to emergency department following a tick bite. We examined the patients and get knowledge about the infestation and we followed up them for possible tick-conducted disease symptoms and laboratory findings both clinically and serologically. MATERIALS AND METHODS: The study presented was hold for one year, between 01...
2017: African Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28666297/-adolescents-and-young-adults-what-would-a-perfect-therapy-look-like
#19
Petra Warschburger
Principal objective Obesity is a major indication for pediatric and adolescent-rehabilitation. Age-specific therapies for "emerging adults" are lacking. The aim was to examine the patients' preferences with respect to the contents and methods of the "perfect therapy" within an inpatient setting. Method In the context of the YOUTH study 147 obese male and female adolescents (aged 15-21 years) filled in standardized questionnaires. Results Overall little age- and gender-specific differences were observed. The participants expressed a preference for interdisciplinary coordinated and coeducational group approaches with involvement of the parents...
June 30, 2017: Die Rehabilitation
https://www.readbyqxmd.com/read/28663606/conscious-sedation-emerging-trends-in-pediatric-dentistry
#20
REVIEW
Joginder Pal Attri, Radhe Sharan, Vega Makkar, Kewal Krishan Gupta, Ranjana Khetarpal, Amar Parkash Kataria
Dental fear and anxiety is a common problem in pediatric patients. There is considerable variation in techniques used to manage them. Various sedation techniques using many different anesthetic agents have gained considerable popularity over the past few years. Children are not little adults; they differ physically, psychologically, and emotionally. The purpose of this review is to survey recent trends and concerning issues in the rapidly changing field of pediatric sedation. We will study the topic from the perspective of an anesthesiologist...
April 2017: Anesthesia, Essays and Researches
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