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https://www.readbyqxmd.com/read/28734263/study-of-the-influencing-factors-of-the-blood-levels-of-toxic-elements-in-africans-from-16-countries
#1
Luis Alberto Henríquez-Hernández, Octavio P Luzardo, Luis D Boada, Cristina Carranza, José Luis Pérez Arellano, Ana González-Antuña, Maira Almeida-González, Carlos Barry-Rodríguez, Manuel Zumbado, María Camacho
Africa's economy is growing faster than any other continent and it has been estimated that the middle class in Africa now exceeds 350 million people. This has meant a parallel increase in the importation of consumer goods and in the implementation of communication and information technologies (ICT), but also in the generation of large quantities of e-waste. However, inadequate infrastructure development remains a major constraint to the continent's economic growth and these highly toxic residues are not always adequately managed...
July 19, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28733811/pharmacological-evidence-that-5-ht2c-receptor-blockade-selectively-improves-decision-making-when-rewards-are-paired-with-audiovisual-cues-in-a-rat-gambling-task
#2
Wendy K Adams, Chris Barkus, Jacqueline-Marie N Ferland, Trevor Sharp, Catharine A Winstanley
RATIONALE: Adding reward-concurrent cues to a rat gambling task (rGT) increases risky choice. This cued version of the task may reflect an "addiction-like" cognitive process, more similar to human gambling than the uncued task. Serotonergic drugs that target 5-HT2 receptors alter mechanisms linked to impulse control. However, relatively little is known regarding the impact of such agents on either risky decision making, or the ability of conditioned stimuli to bias the choice process, despite potential relevance to addiction development and treatment...
July 21, 2017: Psychopharmacology
https://www.readbyqxmd.com/read/28732332/heavy-metal-partitioning-of-suspended-particulate-matter-water-and-sediment-water-in-the-yangtze-estuary
#3
Chenghong Feng, Xiaoyu Guo, Su Yin, Chenhao Tian, Yangyang Li, Zhenyao Shen
The partitioning of ten heavy metals (As, Cd, Co, Cr, Cu, Hg, Ni, Pb, Sb, and Zn) between the water, suspended particulate matter (SPM), and sediments in seven channel sections during three hydrologic seasons in the Yangtze Estuary was comprehensively investigated. Special attention was paid to the role of tides, influential factors (concentrations of SPM and dissolved organic carbon, and particle size), and heavy metal speciation. The SPM-water and sediment-water partition coefficients (Kp) of the heavy metals exhibited similar changes along the channel sections, though the former were larger throughout the estuary...
July 17, 2017: Chemosphere
https://www.readbyqxmd.com/read/28731110/a-redox-controlled-electrolyte-for-plasmonic-enhanced-dye-sensitized-solar-cells
#4
Yuqiao Fu, Siu-Pang Ng, Guangyu Qiu, Tak-Fu Hung, Chi-Man Lawrence Wu, Chun-Sing Lee
Plasmonic enhanced dye-sensitized solar cells (DSSCs) with metallic nanostructures suffer from corrosion problems, especially with the presence of the iodine/triiodide redox couple in the electrolyte. Herein, we introduce an alternative approach by compensating the corrosion with a modified liquid electrolyte. In contrast to the existing method of surface preservation for plasmonic nanostructures, the redox-controlled electrolyte (RCE) contains iodoaurate intermediates, i.e. gold(i) diiodide (AuI2(-)) and gold(iii) tetraiodide (AuI4(-)) with optimal concentrations, such that these intermediates are readily reduced to gold nanoparticles during the operation of DSSCs...
July 21, 2017: Nanoscale
https://www.readbyqxmd.com/read/28730623/effects-of-fluoride-modified-titanium-surfaces-with-the-similar-roughness-on-runx2-gene-expression-of-osteoblast-like-mg63-cells
#5
Ji-Hyoun Lee, Jai-Young Koak, Young-Jun Lim, Ho-Beom Kwon, Hyunjoon Kong, Myung-Joo Kim
Chemical modification of titanium surfaces by hydrofluoric acid (HF) is an effective method to improve bone responses on titanium implant surfaces. In the present study, titanium disks were sandblasted with titanium oxide grits and modified with 0.2% and 0.4% of diluted HF under different exposure times of 40 and 60 s. Surface characteristics, such as surface chemical composition, surface topography, and surface wettability, were investigated. To examine MG63 osteoblast-like cell responses to fluoride-modified titanium surfaces with roughness similar to that of nonmodified surfaces, a cell proliferation assay was performed and gene expression levels of Runx2 were evaluated using real-time PCR...
July 21, 2017: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/28728994/a-comprehensive-analysis-of-cribriform-morphology-on-mr-us-fusion-biopsy-correlated-with-radical-prostatectomy-specimens
#6
Matthew Truong, Changyong Feng, Gary Hollenberg, Eric Weinberg, Edward M Messing, Hiroshi Miyamoto, Thomas P Frye
PURPOSE: Recently, a large body of evidence has emerged recognizing that cribriform morphology is an aggressive prostate cancer morphological pattern associated with higher cancer-specific mortality. In a comprehensive analysis, we compared traditional and contemporary prostate biopsy techniques for detection of prostate cancer with cribriform morphology and used radical prostatectomy as a reference standard. MATERIALS AND METHODS: A retrospectively maintained single institution multiparametric MRI (mpMRI) database (n = 1,001) was queried to identify 240 patients who underwent MR/US fusion targeted biopsy (TB) and concurrent systematic biopsy (SB) from December 2014 to December 2016...
July 17, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28726966/ab-initio-performance-predictions-of-single-layer-in-v-tunnel-field-effect-transistors
#7
Juan Lu, Zhi-Qiang Fan, Jian Gong, Xiang-Wei Jiang
The device performances of both n-type and p-type tunnel field-effect transistors (TFETs) made of single-layer InX (X = N, P, As, Sb) are theoretically evaluated through density functional theory (DFT) and ab initio simulations in this paper. It is found that a promising steep subthreshold swing (SS) of [less-than-or-eq] 60 mV dec(-1) can be obtained with gate length LG = 15.2 nm for all two-dimensional (2D) InX TFETs. In particular, an outstanding on-current of ∼1058 μA μm(-1) (or 880 μA μm(-1)) is estimated in a 2D p-type (or n-type) InSb device, which could barely satisfy the ITRS requirements for future high-performance (HP) applications...
July 20, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28725584/magnetic-resonance-imaging-detection-of-prostate-cancer-in-men-with-previous-negative-prostate-biopsy
#8
REVIEW
Matthew Truong, Thomas P Frye
Use of transrectal ultrasound guided systematic prostate biopsy has poor diagnostic accuracy for prostate cancer (PCa) detection. Recently multiparametric MRI (mpMRI) of the prostate and MR/US fusion biopsy has been gaining popularity for men who have previously undergone a negative biopsy. We performed PubMed(®) and Web of Science(®) searches to identify studies on this subject, particularly focusing on studies consisting of patients who have had at least one previously negative biopsy. Across the literature, when a suspicious lesion is found on mpMRI, MR/US fusion biopsy has consistently demonstrated higher detection rate for any PCa and clinically significant PCa (csPCa) compared to the traditional repeat systematic biopsy (SB) approach...
June 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28725580/pre-biopsy-mri-as-an-adjunct-for-cancer-detection-in-men-with-elevated-psa-and-no-previous-biopsy
#9
REVIEW
Facundo Uriburu-Pizarro, Veeru Kasivisvanathan, Philippe Puech, Arnauld Villers
The role of magnetic resonance imaging (MRI) prior to biopsy in the diagnosis of prostate cancer in biopsy-naïve patients has been strengthened by recent developments such as the PIRADS V2 criteria, which cover acquisition, interpretation, and reporting for clinical practice and data collection for research. Important questions on the role of prostate MRI remain: can MRI be used as a triage test before first biopsy series? Can it be used to avoid the use of systematic biopsies (SB) and instead use only targeted biopsies (TB) to MRI-suspicious lesions? Studies to evaluate image guided TB compared to SB have started to accumulate...
June 2017: Translational Andrology and Urology
https://www.readbyqxmd.com/read/28724549/identification-of-new-tumor-suppressor-genes-in-triple-negative-breast-cancer
#10
Roberto Rangel, Liliana Guzman-Rojas, Takahiro Kodama, Michiko Kodama, Justin Y Newberg, Neal G Copeland, Nancy A Jenkins
Although genomic sequencing has provided a better understating of the genetic landmarks in triple-negative breast cancer (TNBC), functional validation of candidate cancer genes (CCG) remains unsolved. In this study, we used a transposon mutagenesis strategy based on a two-step Sleeping Beauty (SB) forward genetic screen to identify and validate new tumor suppressors (TS) in this disease. We generated 120 siRNAs targeting 40 SB-identified candidate breast cancer TS genes and used them to downregulate expression of these genes in four human TNBC cell lines...
July 19, 2017: Cancer Research
https://www.readbyqxmd.com/read/28724266/preparation-and-enhanced-catalytic-hydrogenation-activity-of-sb-palygorskite-pal-nanoparticles
#11
Lin Tan, Muen He, Aidong Tang, Jing Chen
A Sb/palygorskite (PAL) composite was synthesized by a facile solvothermal process and applied in catalytic hydrogenation of p-nitrophenol for the first time. It was found that the Sb nanoparticles with the sizes of 2-5 nm were well dispersed on the fiber of PAL, while partial aggregated Sb nanoparticles with sizes smaller than 200 nm were also loaded on the PAL. The Sb/PAL composite with 9.7% Sb mass amounts showed outstanding catalytic performance by raising the p-nitrophenol conversion rate to 88.3% within 5 min, which was attributed to the synergistical effect of Sb and PAL nanoparticles facilitating the adsorption and catalytic hydrogenation of p-nitrophenol...
December 2017: Nanoscale Research Letters
https://www.readbyqxmd.com/read/28723066/antimony-anchored-with-nitrogen-doping-porous-carbon-as-high-performance-anode-materials-for-na-ion-batteries
#12
Tianjing Wu, Hongshuai Hou, Chenyang Zhang, Peng Ge, Zhaodong Huang, Mingjun Jing, Xiaoqing Qiu, Xiaobo Ji
Antimony represents a class of unique functional materials in sodium-ion batteries with high theoretical capacity (660 mAh g-1). The utilization of carbonaceous materials as buffer layer has been considered as an effective approach to alleviate rapid capacity fading. Herein, the antimony/nitrogen-doping porous carbon (Sb/NPC) composite with polyaniline nanosheets as carbon source has been successfully achieved. And, our strategy involves three processes-tunable organic polyreaction, thermal annealing process and cost-effective reduction reaction...
July 19, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28722450/two-new-sandwich-type-manganese-mn5-substituted-polyoxotungstates-syntheses-crystal-structures-electrochemistry-and-magnetic-properties
#13
Rakesh Gupta, Imran Khan, Firasat Hussain, A Martin Bossoh, Israël M Mbomekallé, Pedro de Oliveira, Masahiro Sadakane, Chisato Kato, Katsuya Ichihashi, Katsuya Inoue, Sadafumi Nishihara
Herein we report two pentanuclear Mn(II)-substituted sandwich-type polyoxotungstate complexes, [{Mn(bpy)}2Na(H2O)2(MnCl)2{Mn(H2O)}(AsW9O33)2](9-) and [{Mn(bpy)}2Na(H2O)2(MnCl){Mn(H2O)}2(SbW9O33)2](8-) (bpy = 2,2'-bipyridine), whose structures have been obtained by single-crystal X-ray diffraction (SCXRD), complemented by results obtained from elemental analysis, electrospray ionization mass spectrometry, Fourier transform infrared spectroscopy, and thermogravimetric analysis. They consist of two [B-α-XW9O33](9-) subunits sandwiching a cyclic assembly of the hexagonal [{Mn(bpy)}2Na(H2O)2(MnCl)2{Mn(H2O)}](9+) and [{Mn(bpy)}2Na(H2O)2(MnCl){Mn(H2O)}2](10+) moieties, respectively, and represent the first pentanuclear Mn(II)-substituted sandwich-type polyoxometalates (POMs)...
July 19, 2017: Inorganic Chemistry
https://www.readbyqxmd.com/read/28722223/the-role-of-%C3%AE-adrenergic-receptors-and-p38mapk-signaling-pathways-in-physiological-processes-of-cardiosphere-derived-cells
#14
Wen-Bo Zhang, Yun-Qi Liu, Xi Zhang, Lin Lin, Sheng-Li Yin
The effects of β adrenergic receptors (β-ARs) and p38 mitogen-activated protein kinases (MAPK) pathways on cardiosphere-derived cells (CDCs) are largely unknown. This study aimed to investigate the roles of β-ARs and p38MAPK pathways on the proliferation, apoptosis and differentiation capacity of CDCs. The CDCs were treated with β1-AR blocker (Met group), β2-AR antagonist (ICI group) and p38MAPK inhibitor (SB group), nonselective β-AR blocker (PRO group), and β-AR agonist (ISO group). The viability, apoptotic rate and differentiation status of CDCs were determined by MST-1 assay, flow cytometery, and Western blot, respectively...
July 19, 2017: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/28719857/in-situ-adjuvant-therapy-using-a-responsive-doxorubicin-loaded-fibrous-scaffold-after-tumor-resection
#15
Ziming Yuan, Wei Wu, Zhongwei Zhang, Zhiyong Sun, Ruoyu Cheng, Guoqin Pan, Xuemin Wang, Wenguo Cui
As tumor microenvironment becoming more and more important in tumor study, the acid pH around or in solid tumors drew lots of attentions. And the progress of drug delivery systems made the responsive-release possible. This time, we fabricated a new-type composite electrospun poly (L-lactide) (PLLA) fibrous scaffolds, that blent with the mesoporous silica particles (MSNs). Further more, we used sodium bicarbonate (SB) as acid sensitive agent which was wrapped inside the MSNs. And doxorubicin (DOX) was also wrapped into MSNs in order to achieve a sustained release to inhibit tumors in mice, which mimicked the remnant breast cancer with surgery...
July 1, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28718018/the-environmental-legacy-of-historic-pb-zn-ag-au-mining-in-river-basins-of-the-southern-edge-of-the-massif-central-france
#16
Françoise Elbaz-Poulichet, Eléonore Resongles, Chrystelle Bancon-Montigny, Sophie Delpoux, Rémi Freydier, Corinne Casiot
The main rivers (Aude, Orb, Herault) that discharge into the Gulf of Lions and the west bank tributaries of the Rhone River including the Gardon have former non-ferrous metal mines in their upper drainage basin. Using unpublished data and data from the literature, this study provides an integrated overview of the contamination of water and sediment along the continent-sea continuum and of its impacts on the biota and on human health. In the upper part of these basins, water and stream sediments are enriched in metal(-loids) compared to median European concentrations...
July 17, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28717653/individual-social-and-environmental-correlates-of-active-transportation-patterns-in-french-women
#17
Camille Perchoux, Christophe Enaux, Jean-Michel Oppert, Mehdi Menai, Hélène Charreire, Paul Salze, Christiane Weber, Serge Hercberg, Thierry Feuillet, Franck Hess, Célina Roda, Chantal Simon, Julie-Anne Nazare
The objectives were (1) to define physical activity (PA) and sedentary behaviors (SB) patterns in daily life contexts (work, leisure, and transportation) in French working women from NutriNet-Santé web-cohort and (2) to identify pattern(s) of active transportation and their individual, social, and environmental correlates. 23,432 participants completed two questionnaires to evaluate PA and SB in daily life contexts and individual representations of residential neighborhood and transportation modes. Hierarchical cluster analysis was performed which identified 6 distinct movement behavior patterns: (i) active occupation, high sedentary leisure, (ii) sedentary occupation, low leisure, (iii) sedentary transportation, (iv) sedentary occupation and leisure, (v) active transportation, and (vi) active leisure...
2017: BioMed Research International
https://www.readbyqxmd.com/read/28717240/elemental-compositions-of-lichens-from-duolun-county-inner-mongolia-china-origin-road-effect-and-species-difference
#18
Hua-Jie Liu, Jing-Gong Wang, Yu Xia, Meng-Jie Yang, Si-Wa Liu, Liang-Cheng Zhao, Xiu-Ping Guo, Yun-Jun Jiang, Xin Li, Qing-Feng Wu, Shi-Bo Fang
To assess the response of lichen elemental compositions to road traffic and species difference in the context of high dust input and anthropogenic emissions, two foliose epiphytic lichens (Phaeophyscia hirtuosa, PHh; Candelaria fibrosa, CAf) were sampled near a road adjacent to Dolon Nor Town (Duolun County, Inner Mongolia, China). Twenty elements (Ba, Ca, Cd, Co, Cr, Cu, Fe, K, Mg, Mn, Mo, Na, Ni, P, Pb, Sb, Sr, Ti, V and Zn) in lichen and surface soil samples were analysed using inductively coupled plasma mass spectrometer (ICP-MS)...
July 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28715171/limitations-of-structural-superlubricity-chemical-bonds-versus-contact-size
#19
Dirk Dietzel, Ján Brndiar, Ivan Štich, André Schirmeisen
Structural superlubricity describes the state of virtually frictionless sliding if two atomically flat interfaces are incommensurate, that is, they share no common periodicity. Despite the exciting prospects of this low friction phenomenon, there are physical limitations to the existence of this state. Theory predicts that the contact size is one fundamental limit, where the critical size threshold mainly depends on the interplay between lateral contact compliance and interface interaction energies. Here we provide experimental evidence for this size threshold by measuring the sliding friction force of differently sized antimony particles on MoS2...
July 17, 2017: ACS Nano
https://www.readbyqxmd.com/read/28714853/unveiling-the-development-of-intracranial-injury-using-dynamic-brain-eit-an-evaluation-of-current-reconstruction-algorithms
#20
Haoting Li, Rongqing Chen, Canhua Xu, Benyuan Liu, Mengxing Tang, Lin Yang, Xiuzhen Dong, Feng Fu
Dynamic brain EIT is a promising technique for continuous monitoring the development of cerebral injury. While there are many reconstruction algorithms available to brain EIT, there is still a lack of study to compare their performance in the context of dynamic brain monitoring. To address the problem, we develop a framework for evaluating different current algorithms with their ability to correctly identify small intracranial conductivity changes. Firstly, a simulation 3D head phantom with realistic layered structure and impedance distribution were developed...
July 17, 2017: Physiological Measurement
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