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Infections desease

B Sushma, Sachin Gugwad, Rajdeep Pavaskar, Shambhvi A Malik
Prion diseases were first discovered by Stanley B. Prusiner who defined prions as infectious, transmissible proteinaceous particles that lack nucleic acid and are composed exclusively of a modified isoform of the noninfectious cellular prion protein (PrPC). These are incurable neurodegenerative conditions affecting both animals and humans. They may be sporadic, infectious or inherited in origin. Human prion diseases include Creutzfeldt-Jakob desease (CJD), Gerstmann- Straussler-Scheinker disease, Kuru and Fatal familial insomnia...
January 2016: Journal of Oral and Maxillofacial Pathology: JOMFP
Daniela Ferreira, Ana M L Seca, Diana C G A, Artur M S Silva
UNLABELLED: Human bacterial infections are still a major public health problem throughout the world. Therefore it is fundamental to understand how pathogenic bacteria interact with their human host and to develop more advanced drugs or vaccines in response to the increasing bacterial resistance. Since iron is essential to bacterial survival and growth inside the host tissues, these microorganisms have developed highly efficient iron-acquisition systems; the most common one involves the secretion of iron chelators into the extracellular environment, known as siderophores, and the corresponding siderophore-membrane receptors or transporters responsible for the iron uptake...
August 11, 2016: Journal of Proteomics
Qing-hua Wang, Wen-jie Shang, Chun-tao Zhao, Shu-wen Zhang, Shou-long Lu, Xiao-dong Liu
OBJECTIVE: To investigate the prevalence of echinococcosis in Gannan Tibetan Autonomous Prefecture of Gansu Province since the implementation of the echinococcosis control project from Sepical Funds for Central Government Subsidies to Local Public Health (2007-2011). METHODS: Eight counties of Hezuo, Lintan, Zhuoni, Luqu, Maqu, Xiahe, Zhouqu, and Diebu were selected as survey sites. The prevalence in the sampled population was investigated by B ultrasound examination...
February 2015: chinese Journal of Parasitology & Parasitic Diseases
Leonardo López, Germán Burguerner, Leonardo Giovanini
BACKGROUND: The spread of an infectious disease is determined by biological and social factors. Models based on cellular automata are adequate to describe such natural systems consisting of a massive collection of simple interacting objects. They characterize the time evolution of the global system as the emergent behaviour resulting from the interaction of the objects, whose behaviour is defined through a set of simple rules that encode the individual behaviour and the transmission dynamic...
2014: BMC Research Notes
Xu Wang, Ross Sager, Weier Cui, Chong Zhang, Hua Lu, Jung-Youn Lee
In plants, mounting an effective innate immune strategy against microbial pathogens involves triggering local cell death within infected cells as well as boosting the immunity of the uninfected neighboring and systemically located cells. Although not much is known about this, it is evident that well-coordinated cell-cell signaling is critical in this process to confine infection to local tissue while allowing for the spread of systemic immune signals throughout the whole plant. In support of this notion, direct cell-to-cell communication was recently found to play a crucial role in plant defense...
June 2013: Plant Cell
V N Buriak, A S Serhyenko
Analysis features of clinical manifestation and pathogenetic mechanisms of development of meningococcal infection is introduced. It is emphasized that in most cases mentioned infection is characterized by mild course as nasopharyngitidis. However relatively seldom developing generalize form put this phatology on third place after intestinal infections and septicemia in structure of child mortality from infection deseases. Occurence of generalize forms of meningococcal infection depend on peculiarity of immune response is followed by release of endotoxin and exotoxin in blood stream...
July 2011: Likars'ka Sprava
E P Kokhan, A S Aleksandrov
Treatment results of 48 patients with mediastinitis after the open cardiac surgery were analyzed. The main mediastinitis risk factors were: the chronic obstructive lung desease, diabetes mekkitus, severe cardiac insufficiency, prolonged operation, the use of artificial blood circulation and sterna instsbility. Major infective agents of mediastinitis were the Gram-positive cocci. The treatment options varied from the prolonged antibiotic therapy to plastic reconstructive surgery, which were determined by the severity of mediastinitis...
2011: Khirurgiia
C Wachters, M Hildebrand
A 29-year old man is admitted in our hospital for a dry cough which appeared a few weeks earlier and is now associated with a breath depending thoracic pain. As an engineer, he is realizing a thesis about the sound waves produced by coughing and is therefore frequently exposed to patients with various pulmonary infections. The chest X-ray, presents predominant pulmonary infiltrates on the periphery of the upper fields of the lungs. Blood analysis revealed a hypereosinophilia of 4.650/microl. The various bacteriological, parasitic and viral investigation tests are negative...
November 2011: Revue Médicale de Bruxelles
Y Traore, N Mounkoro, I Teguete, M Y Djire, A Diallo, M Bagayogo, A Sissoko, T Dolo, A Dolo
AIM: The sexual aggressions pose an important medico - legal problem. The implication of several services is often indispensable to determine the future of this aggression. Our survey objectives were to determine epidemiological and clinical characteristics of sexual aggressions and to specify the judicial continuations. MATERIAL AND METHODS: We did historical cohort survey while recruiting all cases of consultation in the service for sexual aggressions. This survey spreads on a period of 60 months going from January 2004 to December 2008...
2010: Le Mali Médical
E Choppin, S De Wit, M Sosnowski
We report a case of a young HIV-infected woman treated for more than ten years by highly active antiretroviral therapy, presenting a peroperative acute coronary syndrome caused by a hypertensive episode after systemic resorption of locally applied epinephrine during a functional endoscopic sinus surgery. Since patients with multiple risk factors for coronary artery desease seems to be more susceptible to complications of epinephrine injection, this reminds us of the higher cardiovascular risk for HIV patients with long term treatment...
2010: Acta Anaesthesiologica Belgica
V I Iliukhin, T V Senina, M N Trushkina, E V Shubnikova, Iu V Antonov, N V Andropova
Among the known species of Burkholderia only two are obligate pathogens, i.e., B. mallei and B. pseudomallei, causative agents of glanders and melioidosis respectively. The other species are saprophytes as natural inhabitants of water reservoirs and soil, still capable of causing opportunistic infections in humans and animals under definite conditions. All the species of Burkholderia are characterized by high resistance to antibacterials, including antibiotics. By the MICs, the most efficient chemotherapeutics against pathogenic burkholderias are tetracyclines, fluoroquinolones, penems and combined sulfanilamides...
2009: Antibiotiki i Khimioterapii︠a︡, Antibiotics and Chemoterapy [sic]
M V Iverieli, N O Abashidze, Kh B Gogishvili
The aim of the research was to study sensitivity of specific microorganisms from the periodontal pockets of patients with rapidly progressive periodontal disease to Taromentine. 95 patients aged 21 to 35 years (50 women (52,6+/-33,62) and 45 men (47,36+/-3,62)) with rapidly progressive form of periodontal desease were observed. Porphiromonas gingivalis was identifide in 83 out of 95 patients (87,36+/-2,06). Prevotella intermedia - in 31 patients (32,6+/-2,750); Actinobacillus actinomycetemcomitans - in 23 patients (24,2+/-2,050); Bacteroides forsythus - in 19 patients (20,0+/-2,360); Treponema denticola - in 16 patients (16,84+/-2,190); Candida - in 11 patients (11,57+/-1,80)...
April 2009: Georgian Medical News
Grozdana Canak, Jovan Vukadinov, Snezana Brkić, Daniela Svarc, Maja Ruzić, Nadica Kovacević, Milotka Fabri, Jovana Jovanović, Biljana Klasnja, Dejan Cvjetković, Radoslava Doder, Sinisa Sević, Vesna Turkulov, Sandra Stefan-Mikić, Koviljka Knezević, Mirjana Aleksić-Dordević, Tomislav Preveden
INTRODUCTION: Infectious diseases are a part of the history of this region. Devastating epidemics of plague, smallpox, and cholera were frequent during the 18th and the 19th centuries. Other infectious diseases were a serious problem as well: alimentary tract infections, scarlet fever, diphtheria, whooping cough. Geographic position, climate, migrations, as well as the tradition and lack of medical staff and medications, affected the frequency and outcome of infections. THE HISTORY OF THE TREATMENT OF INFECTIOUS DISEASES: Patients with infectious diseases were first treated at home...
November 2007: Medicinski Pregled
C M Surawicz
In summary, altered intestinal ecology is very important in the pathogenesis of antibiotic-associated diarrhea and pseudomembranous colitis. Prevention of AAD has been demostrated with LactobacillusGG, Enterococcus SF68, and S. boulardii. While therapy with antibitics such as vancomycin or metranidazole is effective for PMC, relapse can occur and is difficult to treat. Antibiotics can be given, but another approach of restoring the normal colonic ecology may be more effective. Such therapy has included use of the nontoxigenic strains of C...
1993: International Journal of Antimicrobial Agents
Rosa Divella, Rosanna Lacalamita, Stefania Tommasi, Maria Coviello, Antonella Daniele, Vito Michele Garrisi, Ines Abbate, Giovanni Simone, Cosimo Gadaleta, Angelo Paradiso, Michele Quaranta
BACKGROUND: Liver carcinogenesis seems to be heavely influenced by hepatitis B and C viral (HBV, HCV) infection. The aim of our study was to improve the detection of hepatocellular carcinoma (HCC) by measuring alfa-fetoprotein (AFP) in addition to other molecular markers by estimating the plasma levels of human catalytic fraction of reverse telomerase (hTERT) DNA, plasminogen activator inhibitor-1 (PAI-1) and tissue plasminogen activator (t-PA) in 75 patients with liver desease. PATIENTS AND METHODS: A control group was enrolled (N=30)...
January 2008: Anticancer Research
F Renou, A Gerber, M-P Moiton, D Ferrandiz, J-L Yvin
INTRODUCTION: The most common presenting features of multiple myeloma are bone pain, anemia, renal failure or hypercalcemia. Bacterial infection as the initial presentation of this desease is rare. CLINICAL CASE: We report the case of a 62-year-old man with pneumococcal septic arthritis of the knee revealing a multiple myeloma. DISCUSSION: Pneumococcal infection should lead to a suspicion of underlying illness and especially the multiple myeloma...
March 2007: La Revue de Médecine Interne
J S Lacroix, A Ricchetti Coignard
The nasal mucosa is one of the anatomical region which have the highest density of sensory innervation. The function of this sensory innervation is probably linked to the protection of the lower airways against inhalation of airborne particles and potentially harmful substances. Chronic rhinosinusitis (CRS) is associated with nasal obstruction, rhinorrhea, loss of sense of smell and facial pain or headaches. When allergy or specific hyperreactivity, infection, systemic or genetic deseases have been excluded, the diagnosis of non specific hyperreactivity or neurogenic inflammation is proposed...
October 19, 2005: Revue Médicale Suisse
Ke Lan, Daniel A Kuppers, Subhash C Verma, Nikhil Sharma, Masanao Murakami, Erle S Robertson
Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiological agent contributing to development of Kaposi's sarcoma, primary effusion lymphoma, and multicentric Castleman desease. Following primary infection, latency is typically established. However, the mechanism by which KSHV establishes latency is not understood. We have reported that the latency-associated nuclear antigen (LANA) can repress RTA (for replication and transcription activator) expression by down-regulating its promoter. In this study, we show that RTA is associated with the virion particle...
June 2005: Journal of Virology
F Sene-Diouf, M Ndiaye, A G Diop, A Thiam, A K Ndao, M Diagne, M M Ndiaye, I P Ndiaye
Through a cohort of 93 neuroaids which has been diagnosed at Dakar in our Neurology Department, the authors evaluated the hospital prevalence of retrovirus, detected socio-demographic factors, related AIDS outline the mean neurological picture and try to correlate survival and neurological involvement of these patients. Among 1151 patients who got retroviral blood test, 93 were seropositive (8.1%). On these repartitions 36 were females (38.7%) and 57 males (61.3%). The age goes from 19 to 76 years old. 45 patients (48...
2000: Dakar Médical
I Diagne, N R Diagne-Gueye, K Gaye-Ly, D Sow, B Camara, A Diack-Mbaye, H Signate-Sy, M Ba, M Sarr, C Moreira, N Kuakuvi
Malignant hemopathies are not considered as public health priority in Senegal because of their infrequency in comparison with infections and malnutrition. However they remain usually lethal instead of a great improvement of their prognosis in suitable therapeutic conditions. The objective of this study was to determine the epidemiologic and evolutionnal profile of these pathologies, and identify practical management problems in a reference public pediatric service in Senegal. We retrospectively analysed hospitals registers and records of all patients followed up in Albert Royer Children Hospital of Dakar from january 1989 to december 1998...
2002: Dakar Médical
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