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Pelvic inflammatory disease

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https://www.readbyqxmd.com/read/29162405/identification-of-target-risk-groups-for-population-based-clostridium-difficile-infection-prevention-strategies-using-a-population-attributable-risk-approach
#1
Sung-Hee Oh, Hye-Young Kang
OBJECTIVES: We aimed to determine risk factors associated with Clostridium difficile infection (CDI) and assess the contributions of these factors on CDI burden. METHODS: We conducted a 1:4 matched case-control study using a national claims dataset. Cases were incident CDI without a history of CDI in the previous 84 days, and were age- and sex-matched with control patients. We ascertained exposure, defined as a history of morbidities and drug use within 90 days...
November 18, 2017: International Journal of Infectious Diseases: IJID
https://www.readbyqxmd.com/read/29160004/urological-dysfunction-in-young-women-an-inheritance-of-childhood
#2
Elisabetta Costantini, Ester Illiano, Konstantinos Giannitsas, Marco Prestipino, Antonio Luigi Pastore, Antonio Carbone, Giovanni Palleschi, Raffaele Balsamo, Franca Natale, Donata Villari, Vittorio Bini, Serena Maruccia, Maria-Teresa Filocamo, Alessandro Zucchi
OBJECTIVE: To investigate the correlation of a history of lower urinary tract symptomatology during childhood to lower urinary tract dysfunction in young adult women. SUBJECTS/PATIENTS AND METHODS: This was a multicenter, prospective, case-control study conducted from April 2013 to November 2015. The trial was registered in ClinicalTrials. gov (NCT02185287). Three-hundred women, 18 to 40 years old, participated. Cases were women attending urogynecology clinics for various lower urinary tract complaints and controls were recruited from a healthy population...
November 21, 2017: BJU International
https://www.readbyqxmd.com/read/29146678/cross-organ-sensitisation-between-the-colon-and-bladder-to-pee-or-not-to-pee
#3
Luke Grundy, Stuart M Brierley
Chronic abdominal and pelvic pain are common, debilitating clinical conditions experienced by millions of patients around the globe. The origin of such pain commonly arises from the intestine and bladder, which share common primary roles; the collection, storage and expulsion of waste. These visceral organs are located in close proximity to one another, and also share common innervation from spinal afferent pathways. Chronic abdominal pain, constipation or diarrhoea are primary symptoms for patients with Irritable Bowel Syndrome (IBS) or Inflammatory Bowel Disease (IBD)...
November 16, 2017: American Journal of Physiology. Gastrointestinal and Liver Physiology
https://www.readbyqxmd.com/read/29136127/risk-of-pelvic-inflammatory-disease-in-relation-to-chlamydia-and-gonorrhea-testing-repeat-testing-and-positivity-a-population-based-cohort-study
#4
Joanne Reekie, Basil Donovan, Rebecca Guy, Jane S Hocking, John M Kaldor, Donna B Mak, Sallie Pearson, David Preen, Louise Stewart, James Ward, Bette Liu
Background: There is uncertainty around whether the risks of pelvic inflammatory disease (PID) differ following Chlamydia trachomatis (chlamydia) and Neisseria gonorrhoeae (gonorrhea) infection. We quantified the risk of PID associated with chlamydia and gonorrhea infection and subsequent repeat infections in a whole-population cohort. Methods: A cohort of 315123 Western Australian women, born during 1974-1995, was probabilistically linked to chlamydia and gonorrhea testing records and to hospitalizations and emergency department presentations for PID from 2002 to 2013...
November 9, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29135086/can-mr-enterography-screen-for-perianal-disease-in-pediatric-inflammatory-bowel-disease
#5
Zehour AlSabban, Nicholas Carman, Rahim Moineddin, Ryan T Lo, Sebastian K King, Jacob C Langer, Thomas D Walters, Anne M Griffiths, Peter C Church, Mary-Louise C Greer
BACKGROUND: Pediatric Crohn's disease is associated with perianal disease (PAD). Magnetic resonance enterography (MRE) assesses small bowel involvement in pediatric inflammatory bowel disease (PIBD). Pelvic MRI (P-MRI) is the gold standard for assessing PAD. PURPOSE: To determine if MRE can accurately detect PAD in PIBD, distinguishing perianal fistulae (PAF) from perianal abscesses (PAA), referenced against P-MRI. STUDY TYPE: Retrospective...
November 14, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/29132441/early-screening-for-chlamydia-trachomatis-in-young-women-for-primary-prevention-of-pelvic-inflammatory-disease-i-predict-study-protocol-for-a-randomised-controlled-trial
#6
Jeanne Tamarelle, Anne C M Thiébaut, Bénédicte Sabin, Cécile Bébéar, Philippe Judlin, Arnaud Fauconnier, Delphine Rahib, Layidé Méaude-Roufai, Jacques Ravel, Servaas A Morré, Bertille de Barbeyrac, Elisabeth Delarocque-Astagneau
BACKGROUND: Genital infection with Chlamydia trachomatis (Ct) is the most common bacterial sexually transmitted infection, especially among young women. Mostly asymptomatic, it can lead, if untreated, to pelvic inflammatory disease (PID), tubal factor infertility and ectopic pregnancy. Recent data suggest that Ct infections are not controlled in France and in Europe. The effectiveness of a systematic strategy for Ct screening in under-25 women remains controversial. The main objective of the i-Predict trial (Prevention of Diseases Induced by Chlamydia trachomatis) is to determine whether early screening and treatment of 18- to-24-year-old women for genital Ct infection reduces the incidence of PID over 24 months...
November 13, 2017: Trials
https://www.readbyqxmd.com/read/29110805/a-population-based-epidemiologic-study-of-female-sexual-dysfunction-risk-in-mainland-china-prevalence-and-predictors
#7
Chunni Zhang, Jiali Tong, Lan Zhu, Lei Zhang, Tao Xu, Jinghe Lang, Yu Xie
BACKGROUND: Epidemiologic data on female sexual dysfunction in China are sparse. AIM: To assess the prevalence of risk of female sexual dysfunction in mainland China and its regional and sociodemographic variations and physiologic, pathologic, and behavioral risk factors. METHODS: A survey of the general female population was conducted in mainland China from February 2014 through January 2016. Women were randomly selected using multistage, stratified, cluster sampling...
November 2017: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29105625/curative-effect-of-jin-gangteng-capsule-combined-with-kangfuxiaoyan-suppository-in-the-treatment-of-chronic-pelvic-inflammatory-disease
#8
Shanshan Gao, Qing Zhang
This paper aims to analyze the curative effect of Jin'gangteng capsule combined with Kangfuxiaoyan suppository in the treatment of chronic pelvic inflammatory disease. 97 patients with chronic pelvic inflammatory disease admitted to our hospital from June 2015 to June 2016 were selected and randomly divided into observation group and control group. Patients in control group were treated with Kangfuxiaoyan suppository and patients in the observation group were treated with Jin'gangteng capsule combined with kangfuxiaoyan suppository treatment...
September 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29100864/sustained-simultaneous-delivery-of-metronidazole-and-doxycycline-from-polycaprolactone-matrices-designed-for-intravaginal-treatment-of-pelvic-inflammatory-disease
#9
Meenakshi Pathak, Allan G A Coombes, BoMi Ryu, Peter J Cabot, Mark S Turner, Cheryn Palmer, Dongjie Wang, Kathryn J Steadman
Poly(ɛ-caprolactone) (PCL) intra-vaginal matrices were produced for local delivery of a combination of antibacterials, by rapidly cooling a mixture of drug powders dispersed in PCL solution. Matrices loaded with different combinations of metronidazole (10, 15 and 20% w/w) and doxycycline (10% w/w), were evaluated in vitro for release behavior and antibacterial activity. Rapid 'burst release' of 8-15% of the doxycycline content and 31-37% of the metronidazole content occurred within 24 h when matrices were immersed in simulated vaginal fluid (SVF) at 37°C...
October 31, 2017: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29097007/national-institute-of-allergy-and-infectious-diseases-workshop-report-chlamydia-vaccines-the-way-forward
#10
Guangming Zhong, Robert C Brunham, Luis M de la Maza, Toni Darville, Carolyn Deal
Chlamydia trachomatis (Ct), an intracellular pathogen, is the most common bacterial sexually transmitted infection. In addition to acute cervicitis and urethritis, Ct can lead to serious sequelae of significant public health burden including pelvic inflammatory disease (PID) and infertility. Ct control efforts have not resulted in desired outcomes such as reduced incidence and reinfection, and this highlights the need for the development of an effective Ct vaccine. To this end, NIAID organized a workshop to consider the current status of Ct vaccine research and address critical questions in Ct vaccine design and clinical testing...
October 30, 2017: Vaccine
https://www.readbyqxmd.com/read/29081463/the-expression-of-cyclophilin-a-in-ovarian-endometrioma-its-correlation-with-recurrence-and-vascularity
#11
Akin Usta, Gulay Turan, Ertan Adali
Endometriosis is defined as the presence of functional endometrial tissues outside of the uterine cavity. Ovarian endometrioma is the most common type of endometriosis. It is an estrogen-dependent inflammatory disease that frequently causes infertility and chronic pelvic pain. Cyclophilin A (CyPA) is secreted from various types of cells in response to inflammatory stimuli. Many previous studies have shown that the increased expression and/or heightened plasma levels of CyPA exacerbates inflammation. The aim of this study is to evaluate CyPA immunoreactivity in ovarian endometrioma cyst wall...
October 2017: Tohoku Journal of Experimental Medicine
https://www.readbyqxmd.com/read/29078736/leptrotrichia-amnionii-an-emerging-pathogen-of-postpartum-endometritis
#12
Tine Masschaele, Sophia Steyaert, Ronny Goethals
Leptotrichia amnionii, a recently described fastidious gram-negative anaerobic bacterium, is an opportunistic pathogen of the female urogenital tract. We report a rare case of L. amnionii bacteremia in a patient with postpartum endometritis which was successfully treated by amoxicilline-clavunalate. There is more and more evidence that L. amnonii has its role in Pelvic Inflammatory Disease and postpartum endometritis.
October 27, 2017: Acta Clinica Belgica
https://www.readbyqxmd.com/read/29071853/-guizhi-fuling-capsule-pill-treatment-for-chronic-pelvic-inflammatory-disease%C3%AF-a-systematic-review-of-randomized-clinical-trials
#13
Li-Shuang Zhang, Feng-Wen Yang, Jun-Hua Zhang, Wen-Ke Zheng, Ming-Yan Zhang, Yue Li, Hong-Jie Zhao
This systematic review aims to systematically evaluate the efficacy and safety of Guizhi Fuling Capsule/Pill on the treatment of chronic pelvic inflammatory disease. We searched CNKI datebases,WanFang,SinoMed,PubMed,Embase,The Cochrane Library from the inception to February 2017,to collect randomized controlled trials(RCTs)of Guizhi Fuling Capsule/Pill in treating chronic pelvic inflammation disease.Two reviewers independently screened literature,extracted date and assessed the risk of bias of included studies...
April 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29071846/-advantages-and-evidences-research-on-chinese-medicine-for-treatment-of-pelvic-inflammatory-disease
#14
Kun Ma, Song-Ping Luo, Min Li, Hui-Xian Zhang, Li-Mian Xu, Rui-Hua Zhao, Shao-Bin Wei
Pelvic inflammatory disease is an infectious disease. At present, Western medicine is mainly treated with antibiotics. However, the situation of antibiotics abuse is so grim that the potential risks such as the imbalance of bacteria, the resistance of bacteria, the production of super bacteria and the increase of adverse reactions are becoming more and more serious. Therefore, it is urgent to find a way to supplement or substitute antibiotics for the treatment of this disease. Traditional Chinese medicine treatment of the disease is effective and has its unique advantages...
April 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29063998/diabetes-mellitus-and-the-colon
#15
REVIEW
Marc S Piper, Richard J Saad
Diabetes mellitus (DM) can affect the structure and function of the colon promoting commonly encountered lower gastrointestinal symptoms such as constipation, diarrhea, abdominal distention, bloating, and abdominal pain. Specific colonic disorders for which adults with DM are at greater risk include chronic constipation, enteropathic diarrhea, colorectal cancer (CRC), inflammatory bowel disease, microscopic colitis, and Clostridium difficile colitis. Smooth muscle structure and function, density of the interstitial cells of Cajal, and the health and function of the autonomic and enteric nerves of the colon are all potential affected by DM...
December 2017: Current Treatment Options in Gastroenterology
https://www.readbyqxmd.com/read/29057034/oxidative-stress-and-endometriosis-a-systematic-review-of-the-literature
#16
REVIEW
Gennaro Scutiero, Piergiorgio Iannone, Giulia Bernardi, Gloria Bonaccorsi, Savino Spadaro, Carlo Alberto Volta, Pantaleo Greco, Luigi Nappi
Endometriosis is one of the most common gynaecologic diseases in women of reproductive age. It is characterized by the presence of endometrial tissue outside the uterine cavity. The women affected suffer from pelvic pain and infertility. The complex etiology is still unclear and it is based on three main theories: retrograde menstruation, coelomic metaplasia, and induction theory. Genetics and epigenetics also play a role in the development of endometriosis. Recent studies have put the attention on the role of oxidative stress, defined as an imbalance between reactive oxygen species (ROS) and antioxidants, which may be implicated in the pathophysiology of endometriosis causing a general inflammatory response in the peritoneal cavity...
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/29054721/characterizing-the-association-between-toll-like-receptor-subtypes-and-nephrolithiasis-with-renal-inflammation-in-an-animal-model
#17
Mahmut Taha Olcucu, Kerem Teke, Serdar Yalcin, Erkan Olcucuoglu, Vildan Caner, Nilay Sen Turk, Omer Levent Tuncay
OBJECTIVES: To show experimentally induced renal stone disease and evaluate secondary inflammatory responses in vivo, and to characterize changes in expression of Toll-like receptor (TLR) subtypes in this model. To evaluate the associations of hyperoxaluria-induced renal stone formation and Toll-like receptors (TLRs) expression in a rat inflammation model. METHODS: Twenty 5-6-week-old male Wistar rats were divided into control and hyperoxaluria groups (n=10/group) and supplied with normal water or 1% ethylene glycol, respectively, for 16 weeks...
October 17, 2017: Urology
https://www.readbyqxmd.com/read/29045851/trends-in-pelvic-inflammatory-disease-emergency-department-visits-united-states-2006-2013
#18
Kristen Kreisel, Elaine W Flagg, Elizabeth Torrone
BACKGROUND: Pelvic inflammatory disease is a female genital tract disorder with severe reproductive sequelae. Because of the difficulties in diagnosing pelvic inflammatory disease, it is not a reportable condition in many states. Females seeking care in emergency departments are a sentinel population for pelvic inflammatory disease surveillance. OBJECTIVE: The objective of the study was to determine trends in diagnoses of acute pelvic inflammatory disease in a nationally representative sample of emergency departments...
October 16, 2017: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/29042497/a-single-dual-function-enzyme-controls-the-production-of-inflammatory-nod-agonist-peptidoglycan-fragments-by-neisseria-gonorrhoeae
#19
Jonathan D Lenz, Kathleen T Hackett, Joseph P Dillard
Neisseria gonorrhoeae gonococcus (GC) is a Gram-negative betaproteobacterium and causative agent of the sexually transmitted infection gonorrhea. During growth, GC releases lipooligosaccharide (LOS) and peptidoglycan (PG) fragments, which contribute significantly to the inflammatory damage observed during human infection. In ascending infection of human Fallopian tubes, inflammation leads to increased risk of ectopic pregnancy, pelvic inflammatory disease, and sterility. Of the PG fragments released by GC, most are disaccharide peptide monomers, and of those, 80% have tripeptide stems despite the observation that tetrapeptide stems make up 80% of the assembled cell wall...
October 17, 2017: MBio
https://www.readbyqxmd.com/read/29037929/severe-sepsis-and-acute-myocardial-dysfunction-in-an-adolescent-with-chlamydia-trachomatis-pelvic-inflammatory-disease-a-case-report
#20
Ashley M Morgan, R Claire Roden, Steven C Matson, Grant M Wallace, Hannah L H Lange, Andrea E Bonny
BACKGROUND: Although generally asymptomatic, severe Chlamydia trachomatis (C. trachomatis) infections have been documented. C. trachomatis has been associated with both myocarditis and sepsis. CASE: A 19-year-old female with type 1 diabetes mellitus developed sudden-onset mental status change and shock after resolution of diabetic ketoacidosis. Abdominal and pelvic imaging demonstrated uterine and adnexal inflammation, and pelvic exam confirmed a diagnosis of pelvic inflammatory disease...
October 13, 2017: Journal of Pediatric and Adolescent Gynecology
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