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Pelvic inflammatory disease

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https://www.readbyqxmd.com/read/28928773/mesenchymal-stem-cells-in-restoration-of-fertility-at-experimental-pelvic-inflammatory-disease
#1
Nataliia Volkova, Mariia Yukhta, Anatoliy Goltsev
Inflammatory disorders account for a significant percentage of gynecologic diseases, particularly in women of reproductive age. It is known that stem cells have anti-inflammatory and regenerative properties. Based on this, we investigated the effect of intravenous administration of cryopreserved mesenchymal stem cells (cMSCs) of bone marrow on experimental chronic inflammation of the ovaries. The paper shows that on the 21st day after cMSC therapy, leukocyte infiltration of ovaries was slightly relative to the control group without treatment, and the ratio of developing and atretic follicles in the animals with cMSC injection dramatically increased, while in the control, it still remained on the side of atretic forms...
2017: Stem Cells International
https://www.readbyqxmd.com/read/28928322/assessment-of-urinary-cotinine-levels-in-women-with-gynecological-complaints-at-a-tertiary-care-hospital-a-pilot-study
#2
A G Radhika, Sruthi Bhaskaran, Jagdish Kaur, Anshuja Singla, Tusha Sharma, B D Banerjee
Gynecological effects due to smokeless tobacco exposure are not well studied. This cross-sectional study was undertaken with the objective to evaluate the urinary cotinine levels in women of reproductive age with gynecological complaints. The study was conducted in 2015 at the outpatient clinic of the Department of Obstetrics and Gynecology, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi. A total of 192 consecutive women presenting with gynecological complaints (pelvic inflammatory disease (PID), infertility, and menstrual abnormality) were recruited...
September 2017: Indian Journal of Public Health
https://www.readbyqxmd.com/read/28919861/lactobacillus-rhamnosus-gg-an-overview-to-explore-the-rationale-of-its-use-in-cancer
#3
REVIEW
Giuseppe L Banna, Francesco Torino, Francesco Marletta, Maria Santagati, Rossella Salemi, Elisa Cannarozzo, Luca Falzone, Francesco Ferraù, Massimo Libra
Cancer is the second leading cause of death in the western world. In the era of precision medicine, a significant number of cancer patients can be cured with several anti-cancer therapeutic regimens. However, therapy failure may be caused by treatment side effects, such as diarrhea, especially occurring in patients with gastrointestinal or pelvic malignancies. In particular, diarrhea is one of the most frequent gastrointestinal toxicity during cancer treatment and it can result from nearly bot chemo- and radio-therapeutic strategies currently used...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28915869/frequency-and-genotypes-of-chlamydia-trachomatis-in-patients-attending-the-obstetrics-and-gynecology-clinics-in-jalisco-mexico-and-correlation-with-sociodemographic-behavioral-and-biological-factors
#4
Néstor Casillas-Vega, Rayo Morfín-Otero, Santos García, Jorge Llaca-Díaz, Eduardo Rodríguez-Noriega, Adrián Camacho-Ortiz, Ma de la Merced Ayala-Castellanos, Héctor J Maldonado-Garza, Jesús Ancer-Rodríguez, Guadalupe Gallegos-Ávila, Alberto Niderhauser-García, Elvira Garza-González
BACKGROUND: Chlamydia trachomatis is the causative agent of the most common bacterial sexually transmitted infection worldwide. The aim of this study was to investigate the frequency and genotypes of C. trachomatis in patients attending an obstetrics and gynecology clinic in Jalisco, Mexico and correlates them with sociodemographic, behavioral, and biological factors. METHODS: C. trachomatis detection was performed in endocervical samples from 662 patients by direct fluorescence assay (DFA) and two PCR assays that amplified the phospholipase D endonuclease superfamily protein (PLDESP) and OmpA genes...
September 15, 2017: BMC Women's Health
https://www.readbyqxmd.com/read/28894927/how-to-differentiate-acute-pelvic-inflammatory-disease-from-acute-appendicitis-a-decision-tree-based-on-ct-findings
#5
Kim El Hentour, Ingrid Millet, Emmanuelle Pages-Bouic, Fernanda Curros-Doyon, Nicolas Molinari, Patrice Taourel
PURPOSE: To construct a decision tree based on CT findings to differentiate acute pelvic inflammatory disease (PID) from acute appendicitis (AA) in women with lower abdominal pain and inflammatory syndrome. MATERIALS AND METHODS: This retrospective study was approved by our institutional review board and informed consent was waived. Contrast-enhanced CT studies of 109 women with acute PID and 218 age-matched women with AA were retrospectively and independently reviewed by two radiologists to identify CT findings predictive of PID or AA...
September 11, 2017: European Radiology
https://www.readbyqxmd.com/read/28882163/prevalence-and-significance-of-mycoplasma-genitalium-in-women-living-with-hiv-in-denmark
#6
Anne Marie Rosendahl Madsen, Kristina Thorsteinsson, Anne-Mette Lebech, Merete Storgaard, Terese L Katzenstein, Frederikke F Rönsholt, Isik Somuncu Johansen, Gitte Pedersen, Lars Noerregaard Nielsen, Aase Bengaard Andersen, Jørgen Skov Jensen
OBJECTIVE: Mycoplasma genitalium (M. genitalium) is a sexually transmitted pathogen associated with urethritis, cervicitis, and pelvic inflammatory disease. Previous studies have shown a strong association between M. genitalium and HIV infection, therefore screening and treatment for M. genitalium has been suggested as part of HIV prevention strategies. The objective of this study was to determine the prevalence of M. genitalium in women living with HIV (WLWH) in Denmark, and to compare the result with data on symptoms from the lower abdomen, sexual habits and immune status...
September 7, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28881394/the-effect-of-vaccination-against-human-papillomavirus-on-fecundability
#7
Kathryn A McInerney, Elizabeth E Hatch, Amelia K Wesselink, Ellen M Mikkelsen, Kenneth J Rothman, Rebecca B Perkins, Lauren A Wise
BACKGROUND: The human papillomavirus (HPV) vaccine was developed to prevent infection with strains of HPV that cause cervical cancer. While HPV infection has been associated with reduced semen quality and lower pregnancy rates in some studies, no studies have examined the relationship between HPV vaccination and fecundability. We hypothesize that HPV prevention via vaccination will protect fecundity. METHODS: We analysed data from Pregnancy Study Online (PRESTO), a preconception cohort of North American pregnancy planners...
September 7, 2017: Paediatric and Perinatal Epidemiology
https://www.readbyqxmd.com/read/28864051/-bowel-endometriosis-and-infertility-do-we-need-to-operate
#8
M Bourdon, P Santulli, L Marcellin, M C Lamau, C Maignien, C Chapron
Endometriosis is a benign chronic inflammatory disease, whose pathogenesis is still unclear. Endometriosis is responsible for infertility and/or pelvic pain. One of the most important features of the disease is the heterogeneity (clinical and anatomical: superficial peritoneal, ovarian and/or deep infiltrating lesions). Bowel involvement constitutes one particularly severe form of the disease, affecting 8-12% of women with deep endometriosis. In case of associated infertility, bowel endometriosis constitutes a real therapeutic challenge for gynecologists...
August 29, 2017: Gynecologie, Obstetrique, Fertilite & Senologie
https://www.readbyqxmd.com/read/28838079/developing-a-public-health-response-to-mycoplasma-genitalium
#9
REVIEW
Matthew R Golden, Kimberly A Workowski, Gail Bolan
Although Mycoplasma genitalium is increasingly recognized as a sexually transmitted pathogen, at present there is no defined public health response to this relatively newly identified sexually transmitted infection. Currently available data are insufficient to justify routinely screening any defined population for M. genitalium infection. More effective therapies, data on acceptability of screening and its impact on clinical outcomes, and better information on the natural history of infection will likely be required before the value of potential screening programs can be adequately assessed...
July 15, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28838078/mycoplasma-genitalium-in-women-current-knowledge-and-research-priorities-for-this-recently-emerged-pathogen
#10
REVIEW
Harold C Wiesenfeld, Lisa E Manhart
Health consequences of sexually transmitted diseases disproportionately affect women, making it important to determine whether newly emerged pathogens cause sequelae. Although the pathogenic role of Mycoplasma genitalium in male urethritis is clear, fewer studies have been conducted among women to determine its pathogenic role in the female reproductive tract. Pelvic inflammatory disease (PID) is an important cause of infertility and ectopic pregnancy, and Chlamydia trachomatis and Neisseria gonorrhoeae are recognized microbial causes...
July 15, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28838077/the-unique-microbiology-and-molecular-pathogenesis-of-mycoplasma-genitalium
#11
REVIEW
Chris L McGowin, Patricia A Totten
Mycoplasma genitalium is increasingly appreciated as a common cause of sexually transmitted disease syndromes, including urethritis in men and cervicitis, endometritis, pelvic inflammatory disease, and possibly preterm birth, tubal factor infertility, and ectopic pregnancy in women. Despite these disease associations, which parallel those of Chlamydia trachomatis and Neisseria gonorrhoeae, the mechanisms by which this pathogen elicits inflammation, causes cellular damage, and persists in its only natural host (humans) are unique and are not fully understood...
July 15, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28838072/mycoplasma-genitalium-accurate-diagnosis-is-necessary-for-adequate-treatment
#12
REVIEW
Charlotte A Gaydos
Background: Mycoplasma genitalium is very difficult to grow in culture but has been more able to be studied for disease associations since the advent of research molecular amplification assays. Polymerase chain reaction (PCR) and other molecular assays have demonstrated an association with adverse disease outcomes, such as urethritis or nongonococcal urethritis in men and adverse reproductive sequelae in women-for example, cervicitis, endometritis, and pelvic inflammatory disease (PID), including an association with risk for human immunodeficiency virus...
July 15, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28835360/chlamydia-trachomatis-the-persistent-pathogen
#13
Steven S Witkin, Evelyn Minis, Aikaterini Athanasiou, Julie Leizer, Iara M Linhares
Chlamydia trachomatis is an obligate intracellular bacterium whose only natural host is man. Although asymptomatic in most women, genital tract chlamydial infections are a leading cause of pelvic inflammatory disease, tubal factor infertility and ectopic pregnancy. C. trachomatis has evolved successful mechanisms to avoid destruction by autophagy and the host immune system and persist within host epithelial cells. The intracellular form of this organism, the reticulate body, can enter into a persistent non-replicative but viable state under unfavorable conditions...
August 23, 2017: Clinical and Vaccine Immunology: CVI
https://www.readbyqxmd.com/read/28831136/multi-factors-including-inflammatory-immune-hormones-tumor-related-proteins-and-nutrition-associated-with-chronic-prostatitis-nih-iiia-b-and-iv-based-on-famhes-project
#14
Yang Chen, Jie Li, Yanling Hu, Haiying Zhang, Xiaobo Yang, Yonghua Jiang, Ziting Yao, Yinchun Chen, Yong Gao, Aihua Tan, Ming Liao, Zhen Lu, Chunlei Wu, Xiaoyin Xian, Suchun Wei, Zhifu Zhang, Wei Chen, Gong-Hong Wei, Qiuyan Wang, Zengnan Mo
Chronic prostatitis (CP) is a complex disease. Fragmentary evidence suggests that factors such as infection and autoimmunity might be associated with CP. To further elucidate potential risk factors, the current study utilized the Fangchenggang Area Male Health and Examination Survey (FAMHES) project; where 22 inflammatory/immune markers, hormone markers, tumor-related proteins, and nutrition-related variables were investigated. We also performed baseline, regression, discriminant, and receiver operating characteristic (ROC) analyses...
August 22, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28822590/what-antibiotic-regimen-is-most-efficacious-in-treating-pelvic-inflammatory-disease
#15
EDITORIAL
Brit Long, Michael D April
No abstract text is available yet for this article.
August 16, 2017: Annals of Emergency Medicine
https://www.readbyqxmd.com/read/28794464/expression-changes-in-pelvic-organ-prolapse-a-systematic-review-and-in-silico-study
#16
Maryam B Khadzhieva, Dmitry S Kolobkov, Svetlana V Kamoeva, Lyubov E Salnikova
Pelvic organ prolapse (POP) is a highly disabling condition common for a vast number of women worldwide. To contribute to existing knowledge in POP pathogenesis, we performed a systematic review of expression studies on both specific gene and whole-genome/proteome levels and an in silico analysis of publicly available datasets related to POP development. The most extensively investigated genes in individual studies were related to extracellular matrix (ECM) organization. Three premenopausal and two postmenopausal sets from two Gene Expression Omnibus (GEO) studies (GSE53868 and GSE12852) were analyzed; Gene Ontology (GO) terms related to tissue repair (locomotion, biological adhesion, immune processes and other) were enriched in all five datasets...
August 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28774422/polymyalgia-rheumatica
#17
REVIEW
Miguel A González-Gay, Eric L Matteson, Santos Castañeda
Polymyalgia rheumatica is an inflammatory disease that affects the shoulder, the pelvic girdles, and the neck, usually in individuals older than 50 years. Increases in acute phase reactants are typical of polymyalgia rheumatica. The disorder might present as an isolated condition or in association with giant cell arteritis. Several diseases, including inflammatory rheumatic and autoimmune diseases, infections, and malignancies can mimic polymyalgia rheumatica. Imaging techniques have identified the presence of bursitis in more than half of patients with active disease...
July 31, 2017: Lancet
https://www.readbyqxmd.com/read/28770172/diversity-of-cervical-microbiota-in-asymptomatic-chlamydia-trachomatis-genital-infection-a-pilot-study
#18
Simone Filardo, Marisa Di Pietro, Maria G Porpora, Nadia Recine, Alessio Farcomeni, Maria A Latino, Rosa Sessa
Chlamydia trachomatis genital infection continues to be an important public health problem worldwide due to its increasing incidence. C. trachomatis infection can lead to severe sequelae, such as pelvic inflammatory disease, obstructive infertility, and preterm birth. Recently, it has been suggested that the cervico-vaginal microbiota may be an important defense factor toward C. trachomatis infection as well as the development of chronic sequelae. Therefore, the investigation of microbial profiles associated to chlamydial infection is of the utmost importance...
2017: Frontiers in Cellular and Infection Microbiology
https://www.readbyqxmd.com/read/28765802/clinical-gait-analysis-on-a-patient-undergoing-surgical-correction-of-kyphosis-from-severe-ankylosing-spondylitis
#19
Ram Haddas, Theodore Belanger
BACKGROUND: Ankylosing spondylitis (AS) is a chronic inflammatory disease primarily affecting the axial skeleton, including the sacroiliac joints, costovertebral joints, and the spine. Patients with AS found to have an alter gait pattern. The purpose of this study was to investigate biomechanical alterations in gait after surgical correction in a patient with severe kyphosis from AS. METHODS: A case report in controlled laboratory study, a pretest-posttest design...
2017: International Journal of Spine Surgery
https://www.readbyqxmd.com/read/28762367/socioeconomic-status-of-parents-and-the-occurrence-of-pelvic-inflammatory-disease-among-undergraduates-attending-irrua-specialist-teaching-hospital-irrua-edo-state-nigeria
#20
Tijani Idris Ahmad Oseni, Michael Adeoye Odewale
BACKGROUND: Pelvic inflammatory disease (PID) is a major cause of gynaecological morbidity globally. Complications from PID include infertility, ectopic pregnancy and chronic pelvic pain. Low socioeconomic status (SES) is a risk factor for the occurrence of PID. OBJECTIVE: The aim of this study was to determine the association between SES of parents and the occurrence of PID among undergraduates attending Irrua Specialist Teaching Hospital, Irrua. METHODOLOGY: The study was a hospital-based, descriptive cross-sectional study...
April 2017: Nigerian Postgraduate Medical Journal
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