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https://www.readbyqxmd.com/read/28808491/distribution-patterns-of-the-metastases-of-the-lung-carcinoma-in-relation-to-histological-type-of-the-primary-tumor-an-autopsy-study
#1
Ivana Savic Milovanovic, Mihailo Stjepanovic, Dragan Mitrovic
INTRODUCTION: Lung cancer is among leading causes of death worldwide. Different histological types of the lung carcinoma show significant differences in behavior. OBJECTIVES: The aim of this study is to determine the distribution patterns of metastases of different lung cancer histological types in autopsied individuals. METHODS: Protocols from all autopsies performed at the Institute of Pathology from 2008 till 2014 were reviewed retrospectively, and information on individuals' age, sex, histological type of primary lung cancer, presence and location of metastases, and causes of death were recorded...
July 2017: Annals of Thoracic Medicine
https://www.readbyqxmd.com/read/28804590/feminizing-adrenocortical-carcinoma-without-gynecomastia
#2
Farida Chentli, Fadila Chabour, Djafer Bouchibane, Nouria Nouar
Malignant feminizing adrenocortical tumors are exceedingly rare. Their main presentation is gynecomastia. In these estrogen secreting tumors (with or without other adrenocortical hormones) lack of gynecomastia is exceptional as in our case. A 44-year-old man presented with abdominal pain. Radiological assessment revealed a tumor measuring 120 × 95 mm in the retroperitoneal area with numerous metastases. Pathological examination pleaded for an adrenal origin with a Weiss's score of 5. Six months later, the tumor relapsed, and he had a second surgery and was sent for hormone assessment...
July 2017: Oman Medical Journal
https://www.readbyqxmd.com/read/28801285/-clinical-analysis-of-939-patients-with-adrenal-lesions-detected-by-abdominal-computed-tomography
#3
Cun-Xia Fan, Jia-Jun Zhang, Ying-Ying Cai, Chun-Yan Wu, Shao-Zhou Zou, Yi-Kai Xu, Yao-Ming Xue, Mei-Ping Guan
OBJECTIVE: To investigate the prevalence, etiology and clinical characteristics of adrenal lesions detected by abdominal computed tomography (CT). METHODS: This retrospective study was conducted in patients with adrenal lesions detected by abdominal CT examinations in Nanfang Hospital between July, 2014 and June, 2015. The clinical data of the patients were collected for analysis of the demographics, comorbidities, imaging characteristics, biochemical profiles, clinical diagnosis and intervention...
August 20, 2017: Nan Fang Yi Ke da Xue Xue Bao, Journal of Southern Medical University
https://www.readbyqxmd.com/read/28797997/hepatocellular-carcinoma-peritoneal-metastasis-role-of-cytoreductive-surgery-and-hyperthermic-intraperitoneal-chemotherapy-hipec
#4
John Spiliotis, Georgios Nikolaou, Nikolaos Kopanakis, Dimitra Vassiliadou, Alexios Terra, Elias Efstathiou
INTRODUCTION: Peritoneal dissemination of hepatocellular carcinoma (HCC) is a rare presentation with an incidence of 2-6%. The most common cause of peritoneal deposits is a ruptured HCC that results in tumor spillage into the peritoneal cavity. The overall incidence of spontaneous ruptures of HCC ranges from 5 to 15% and carries a high mortality rate of up to 50%. Other factors influencing peritoneal dissemination are the lymph node metastasis and the direct diaphragmatic invasion and there is no significant association with past history of FNAB, or percutaneous RFA or ethanol injection and lung or adrenal metastasis...
May 2017: Gulf Journal of Oncology
https://www.readbyqxmd.com/read/28767733/lactate-dehydrogenase-and-creatine-kinase-as-poor-prognostic-factors-in-lung-cancer-a-retrospective-observational-study
#5
Lei Liu, Ying He, Ge Ge, Lei Li, Ping Zhou, Yihan Zhu, Huairong Tang, Yan Huang, Weimin Li, Li Zhang
PURPOSE: Circulating molecules play important roles in lung cancer diagnosis. In addition, plasma lactate dehydrogenase (LDH) and creatine kinase (CK) have been shown to be closely related to tumor progression in breast cancer, prostate cancer, and colonel cancer. However, the relationships between LDH and CK levels with metastasis occurrence and the survival status of lung cancer patients remain unclear. EXPERIMENTAL DESIGN: A total of 1142 lung cancer patients were enrolled in this study and were separated into negative or positive groups, according to the plasma levels of CK or LDH...
2017: PloS One
https://www.readbyqxmd.com/read/28764229/upper-gastrointestinal-bleed-as-a-manifestation-of-poorly-differentiated-metastatic-squamous-cell-carcinoma-of-the-lung
#6
Richa Bhardwaj, Gaurav Bhardwaj, Arun Gautam, Raffi Karagozian
Gastrointestinal (GI) metastasis from primary lung cancer is a rare clinical finding. Lung cancer most often metastasizes to the brain, bone, liver, and adrenal glands; with gastrointestinal involvement being very rare. We report a case of a 39-year-old female with a diagnosis of poorly differentiated Squamous Cell Carcinoma (SCC) of the lung presenting with dizziness and melena. Esophagogastroduodenoscopy (EGD) showed a bleeding mass in the stomach. Final biopsy report and Immunohistochemistry (IHC) of the specimen were consistent with SCC lung metastasis...
June 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28763336/metastatic-cutaneous-paraganglioma-a-case-report-and-review-of-the-literature
#7
Dianne de Leon, Kara Walton, Olayemi Sokumbi
Paragangliomas are rare neoplasms that arise from chromaffin cells of the sympathetic and parasympathetic nervous system. These tumors are often cured by surgical resection but the risk for metastatic disease exists, particularly for extra-adrenal paragangliomas. The behavior of these tumors is unpredictable, and clinical and histopathological features associated with malignancy have not been determined. The most common sites of metastases include local and distant lymph nodes, bone, liver, and lung. Cutaneous metastases are exceedingly rare with only 2 reported cases, both of which presented on the scalp...
July 24, 2017: American Journal of Dermatopathology
https://www.readbyqxmd.com/read/28754418/surgical-treatment-of-adrenal-carcinoma
#8
S Gaujoux, M Weinandt, S Bonnet, V Reslinger, J Bertherat, B Dousset
Adrenocortical carcinoma (ACC) is a rare disease with a poor prognosis. The presence of a mass syndrome or signs of hormonal hypersecretion often lead to its discovery, but more and more frequently, adrenocortical malignancy is fortuitously discovered as an incidentaloma. Cross-sectional imaging (CT and MRI) often points to the malignant character of the adrenal mass. Needle biopsy is contraindicated. Laboratory testing showing combined hypersecretion of cortisol, androgens or inactive corticosteroid precursors is highly suggestive of ACC...
July 25, 2017: Journal of Visceral Surgery
https://www.readbyqxmd.com/read/28749001/-carney-triad-report-of-one-case
#9
Jorge Vega, Jorge Navarro Subiabre, Cristian Lovera Riquelme, Héctor Opazo, Mario Santamarina
Carney described a disorder characterized by the presence of several uncommon tumors which were pulmonary chondromas, gastric sarcomas and extra-adrenal paragangliomas. We report a 14 year-old girl in whom multiple gastric tumors were discovered during a study of an iron deficiency anemia and was subjected to a partial gastrectomy. At 25 years of age, she developed several pulmonary chondromas and at 33 years, a mediastinal tumor with features of an extra-adrenal paraganglioma was found. At 35 years of age, a total gastrectomy was performed to remove a gastrointestinal stromal tumor with excision of peritoneal and lymph node metastasis...
April 2017: Revista Médica de Chile
https://www.readbyqxmd.com/read/28747211/fluorodeoxyglucose-positron-emission-tomography-computed-tomography-imaging-features-of-colloid-adenocarcinoma-of-the-lung-a-case-report
#10
ZhenGuang Wang, MingMing Yu, YueHua Chen, Yan Kong
BACKGROUND: Colloid adenocarcinoma of the lung is a rare subtype of variants of invasive adenocarcinomas. We report the appearance of this unusual entity on (18)F-fluorodeoxyglucose positron emission tomography/computed tomography. CASE PRESENTATION: A 60-year-old man of Chinese Han nationality coughed with a little white sputum for 1 month. Chest computed tomography showed multiple bilateral subpleural nodules and plaques accompanied by air bronchograms, which were most concentrated in the lower lobe of his right lung...
July 27, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28742373/utility-of-mri-to-differentiate-clear-cell-renal-cell-carcinoma-adrenal-metastases-from-adrenal-adenomas
#11
Nicola Schieda, Satheesh Krishna, Matthew D F McInnes, Bardia Moosavi, Abdulmohsen Alrashed, Robert Moreland, Evan S Siegelman
OBJECTIVE: The purpose of this study is to compare MRI features of clear cell renal cell carcinoma (RCC) adrenal metastases and adenomas. MATERIALS AND METHODS: Fifteen clear cell RCC adrenal metastases imaged with MRI were compared to 29 consecutive adenomas between 2006 and 2015. Two blinded radiologists assessed homogeneity (homogeneous vs heterogeneous), signal intensity (SI) decrease on chemical-shift MRI, and T2-weighted SI (isointense, mildly hyperintense, or markedly hyperintense) relative to muscle...
July 25, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28695321/angiogenesis-and-lymphangiogenesis-in-the-adrenocortical-tumors
#12
Sofia S Pereira, Madalena M Costa, Susana G Guerreiro, Mariana P Monteiro, Duarte Pignatelli
Adrenocortical tumors (ACT) are common adrenal tumors. The majority of ACTs are non-functioning and benign, while adrenocortical carcinomas (ACC) are rare, usually very aggressive and often metastasized when first diagnosed. Our aim was to assess whether blood and lymph vessel density within ACTs correlate with the malignancy character or tumor functionality. For that, the microvascular distribution was evaluated by immunohistochemistry staining with D2-40 antibody, for lymph vessels and CD-31 antibody, for blood vessels, in ACCs (n = 15), adenomas with Cushing syndrome (n = 9) and non-functioning adenomas (n = 10)...
July 10, 2017: Pathology Oncology Research: POR
https://www.readbyqxmd.com/read/28684242/-hypofractionated-stereotactic-body-radiation-therapy-for-adrenal-metastases
#13
G Dupic, J Biau, A Bellière-Calandry, M Lapeyre
Adrenal glands are a common site for metastatic spread since they represent the fourth metastatic site of solid tumors. Interest in local ablative treatments of oligometastases is growing since literature suggests better progression-free survival, quality of life and potentially overall survival in selected patients. Surgery remains the first treatment of adrenal oligometastases because results are good, with a long enough follow-up. However, stereotactic radiotherapy appears to be comparable to surgery and could be proposed to elderly, unfit, inoperable patients, or even to patients whose systemic treatment should not be suspended for too long...
August 2017: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
https://www.readbyqxmd.com/read/28670184/unusual-asymptomatic-fluorodeoxyglucose-avid-pheochromocytoma-in-a-case-of-myxoid-liposarcoma-of-the-extremity-on-18-f-fluorodeoxyglucose-positron-emission-tomography-computed-tomography
#14
Divya Shivdasani, Natasha Singh, Melvika Pereira, Anand Zade
Sarcomas are a heterogeneous group of rare tumors and arise either from soft tissue or from bone. Soft-tissue sarcomas (STSs) initially metastasize to the lungs. Metastases to extrapulmonary sites such as liver, brain, and soft tissue distant from primary tumor usually develop later. However, cases with isolated adrenal metastasis without disseminated disease have been reported in literature. We present a case of primary myxoid liposarcoma of the lower limb, in which staging (18)-F fluorodeoxyglucose positron emission tomography-computed tomography (FDG PET-CT) scan detected a suspicious FDG avid adrenal lesion which eventually on resection was diagnosed as asymptomatic pheochromocytoma...
July 2017: World Journal of Nuclear Medicine
https://www.readbyqxmd.com/read/28659974/esophageal-cancer-metastases-to-unexpected-sites-a-systematic-review
#15
REVIEW
Osama Shaheen, Abdulaziz Ghibour, Bayan Alsaid
The most common pattern of esophageal cancer metastases (ECM) is to the lymph nodes, lung, liver, bones, adrenal glands, and brain. On the other hand, unexpected metastasis (UM) spread to uncommon sites has increasingly reported and consequently affected the pathway of diagnosis, staging, and management. Using the PubMed database, a systematic search of the following headings "Esophageal" and "Metastasis" or "Metastases" was performed, 10049 articles were identified, and the articles were included if they demonstrated unexpected ECM...
2017: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/28632691/18f-fdg-uptake-in-benign-fibrous-histiocytoma-of-adrenal-gland-a-potential-pitfall
#16
Teik Hin Tan, Christina Nye Bing Lai
A 47-year-old man with newly diagnosed nasopharyngeal carcinoma underwent staging F-FDG PET/CT. Apart from showing increased FDG uptake in the primary site and locoregional nodal and liver metastases, an unusual site of intense FDG focus was demonstrated in the left adrenal gland. He underwent CT-guided biopsy, and the histopathologic diagnosis was benign fibrous histiocytoma.
August 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/28625645/eus-b-fna-vs-conventional-eus-fna-for-left-adrenal-gland-analysis-in-lung-cancer-patients
#17
Laurence M M J Crombag, Artur Szlubowski, Jos A Stigt, Olga Schuurbiers, Daniël A Korevaar, Peter I Bonta, Jouke T Annema
INTRODUCTION: In patients with lung cancer, left adrenal glands (LAG) suspected for distant metastases (M1b) based on imaging require further evaluation for a definitive diagnosis. Tissue acquisition is regularly performed using conventional EUS-FNA. The aim of this study was to investigate the success rate of endoscopic ultrasound guided fine-needle aspiration using the EBUS scope (EUS-B-FNA) for LAG analysis. METHODS: This is a prospective multicenter study in consecutive patients with (suspected) lung cancer and suspected mediastinal and LAG metastases...
June 2017: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
https://www.readbyqxmd.com/read/28625628/which-patients-with-es-sclc-are-most-likely-to-benefit-from-more-aggressive-radiotherapy-a-secondary-analysis-of-the-phase-iii-crest-trial
#18
Ben J Slotman, Corinne Faivre-Finn, Harm van Tinteren, Astrid Keijser, John Praag, Joost Knegjens, Matthew Hatton, Iris van Dam, Annija van der Leest, Bart Reymen, Jos Stigt, Kate Haslett, Devashish Tripathi, Egbert F Smit, Suresh Senan
INTRODUCTION: In ES-SCLC patients with residual intrathoracic disease after first-line chemotherapy, the addition of thoracic radiotherapy reduces the risk of intrathoracic recurrence, and improves 2-year survival. To identify patient subgroups for future trials investigating higher dose (extra)thoracic radiotherapy, we investigated the prognostic importance of number and sites of metastases in patients included in the CREST trial. MATERIALS/ METHODS: Additional data on sites and numbers of metastases were collected from individual records of 260 patients from the top 9 recruiting centers in the randomized CREST trial (53% of 495 study patients), which compared thoracic radiotherapy (TRT) to no TRT in ES-SCLC patients after any response to chemotherapy...
June 2017: Lung Cancer: Journal of the International Association for the Study of Lung Cancer
https://www.readbyqxmd.com/read/28616158/synchronous-contralateral-adrenal-metastasis-of-colorectal-cancer-case-report
#19
Micaela Raices, Luis Boccalatte, Gustavo Rossi, Fernando Wright
The most frequent sites of distant metastasis of colorectal cancer (CRC) are primarily liver and lung, followed by brain and bone metastases. Infrequently, metastases are found in the adrenal glands. They usually have a metachronous and homolateral character. We present a case of contralateral synchronic adrenal metastasis of CRC and its surgical resolution.
June 2017: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/28610697/respiratory-motion-of-adrenal-gland-metastases-analyses-using-four-dimensional-computed-tomography-images
#20
Bing Chen, Yong Hu, Jin Liu, An-Ning Cao, Lu-Xi Ye, Zhao-Chong Zeng
PURPOSE: To evaluate the respiratory motion of adrenal gland metastases in three-dimensional directions using four-dimensional computed tomography (4DCT) images. METHODS: From January 2013 to May 2016, 12 patients with adrenal gland metastases were included in this study. They all underwent 4DCT scans to assess respiratory motion of adrenal gland metastases in free breathing state. The 4DCT images were sorted into 10 image series according to the respiratory phase from the end inspiration to the end expiration, and then transferred to FocalSim workstation...
June 2017: Physica Medica: PM
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