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https://www.readbyqxmd.com/read/28544367/the-diverging-trajectories-of-cannabis-and-tobacco-policies-in-the-united-states-reasons-and-possible-implications
#1
Wayne Hall, Lynn T Kozlowski
AIM: To examine briefly the (i) rationales for two policy proposals in the United States to make it mandatory for cigarettes to contain very low levels of nicotine and to legalize cannabis for recreational use by adults; and (ii) possible lessons that participants in each policy debate may learn from each other. METHOD: We briefly describe the diverging policies towards cannabis and tobacco in the United States, explain and critically analyse their rationales and discuss possible policy lessons...
May 22, 2017: Addiction
https://www.readbyqxmd.com/read/28542296/traders-guns-and-money-the-effects-of-mass-shootings-on-stock-prices-of-firearm-manufacturers-in-the-u-s
#2
Anandasivam Gopal, Brad N Greenwood
We investigate how mass shootings influence the stock price of firearms manufacturers. While it is well known that mass shootings lead to increased firearms sales, the response from financial markets is unclear. On one hand, given the observed short-term increase in demand, firearm stock prices may rise due to the unexpected financial windfall for the firm. On the other, mass shootings may result in calls for regulation of the industry, leading to divestment of firearms stocks in spite of short-term demand...
2017: PloS One
https://www.readbyqxmd.com/read/28527520/recent-advances-in-smart-biotechnology-hydrogels-and-nanocarriers-for-tailored-bioactive-molecules-depot
#3
REVIEW
Gesmi Milcovich, Stefania Lettieri, Filipe E Antunes, Bruno Medronho, Ana C Fonseca, Jorge F J Coelho, Paolo Marizza, Francesca Perrone, Rossella Farra, Barbara Dapas, Gabriele Grassi, Mario Grassi, Silvia Giordani
Over the past ten years, the global biopharmaceutical market has remarkably grown, with ten over the top twenty worldwide high performance medical treatment sales being biologics. Thus, biotech R&D (research and development) sector is becoming a key leading branch, with expanding revenues. Biotechnology offers considerable advantages compared to traditional therapeutic approaches, such as reducing side effects, specific treatments, higher patient compliance and therefore more effective treatments leading to lower healthcare costs...
May 9, 2017: Advances in Colloid and Interface Science
https://www.readbyqxmd.com/read/28522642/influence-of-drug-class-and-healthcare-setting-on-systemic-antifungal-expenditures-in-the-united-states-2005-15
#4
Margaret A Fitzpatrick, Katie J Suda, Charlesnika T Evans, Robert J Hunkler, Frances Weaver, Glen T Schumock
PURPOSE: Overall and specific class trends in systemic antifungal expenditures in various U.S. healthcare settings from 2005 through 2015 were evaluated. METHODS: Systemic antifungal expenditures from January 1, 2005, through December 31, 2015, were obtained from the QuintilesIMS National Sales Perspective database, which provides a statistically valid projection of medication purchases from multiple markets throughout the United States. Summary data for total antifungal expenditures over the entire period are reported, as are growth and the percentage change in expenditures from one year to the next...
May 18, 2017: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/28522031/-the-french-medecine-pricing-committee-and-the-medicine-economic-policy-rules-and-competences
#5
D Giorgi
The French medicine pricing committee (CEPS), a governmental and inter-institutional body exercises essential competences for the regulation of the economy of the reimbursable drugs in France. It provides a good example of administered price regulation. It also supervises the proper use of products (control of promotion, conventional control of sales volumes). Finally, it regulates the annual envelope of drug expenditures by means of discounts paid by pharmaceutical companies. The article presents the legal criteria and the doctrine of price setting used in France...
May 15, 2017: Annales Pharmaceutiques Françaises
https://www.readbyqxmd.com/read/28506275/global-survey-of-malaria-rapid-diagnostic-test-rdt-sales-procurement-and-lot-verification-practices-assessing-the-use-of-the-who-find-malaria-rdt-evaluation-programme-2011-2014
#6
Sandra Incardona, Elisa Serra-Casas, Nora Champouillon, Christian Nsanzabana, Jane Cunningham, Iveth J González
BACKGROUND: Malaria rapid diagnostic tests (RDTs) play a critical role in malaria case management, and assurance of quality is a key factor to promote good adherence to test results. Since 2007, the World Health Organization (WHO) and the Foundation for Innovative New Diagnostics (FIND) have coordinated a Malaria RDT Evaluation Programme, comprising a pre-purchase performance evaluation (product testing, PT) and a pre-distribution quality control of lots (lot testing, LT), the former being the basis of WHO recommendations for RDT procurement...
May 15, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28505629/impacts-and-mitigation-of-excess-diesel-related-nox-emissions-in-11-major-vehicle-markets
#7
Susan C Anenberg, Joshua Miller, Ray Minjares, Li Du, Daven K Henze, Forrest Lacey, Christopher S Malley, Lisa Emberson, Vicente Franco, Zbigniew Klimont, Chris Heyes
Vehicle emissions contribute to fine particulate matter (PM2.5) and tropospheric ozone air pollution, affecting human health, crop yields and climate worldwide. On-road diesel vehicles produce approximately 20 per cent of global anthropogenic emissions of nitrogen oxides (NOx), which are key PM2.5 and ozone precursors. Regulated NOx emission limits in leading markets have been progressively tightened, but current diesel vehicles emit far more NOx under real-world operating conditions than during laboratory certification testing...
May 15, 2017: Nature
https://www.readbyqxmd.com/read/28496471/ionic-liquid-assisted-synthesis-of-celexocib-using-tris-2-hydroxyethyl-ammonium-acetate-as-an-efficient-and-reusable-catalyst
#8
Hamid Reza Ahfad-Hosseini, Hasan Bagheri, Salimeh Amidi
Celecoxib is classified as none traditional nonsteroidal anti-inflammatory drugs (NSAIDs). This compound has conventional properties of NSAIDs such as anti-inflammatory, analgesic, and antipyretic activities beside reduced risk of gastrointestinal side effect of traditional NSAIDs such as ibuprofen. This compound gets a second sale rank of NSAIDs market at 2016 in the world and sales more than 17000 Kg in Iran during the past 6 month. So, a simple, rapid and green method for synthesis of this compound is important...
2017: Iranian Journal of Pharmaceutical Research: IJPR
https://www.readbyqxmd.com/read/28488037/point-of-sale-e-cigarette-advertising-among-tobacco-stores
#9
Neng Wan, Mohammad Siahpush, Raees A Shaikh, Molly McCarthy, Athena Ramos, Antonia Correa
The marketing expenditure and sale of e-cigarettes increased sharply in the United States in recent years. However, little is known about neighborhood characteristics of point-of-sale (POS) e-cigarette advertising among tobacco stores. The purpose of this study was to examine socio-demographic characteristics of POS e-cigarette advertising among tobacco stores in the Omaha metropolitan area of Nebraska, USA. Between April and June 2014, trained fieldworkers completed marketing audits of all stores that sell tobacco (n = 463) in the Omaha metropolitan area and collected comprehensive e-cigarette advertising data of these stores...
May 9, 2017: Journal of Community Health
https://www.readbyqxmd.com/read/28483810/evidentiary-support-in-public-comments-to-the-fda-s-center-for-tobacco-products
#10
Natalie Hemmerich, Elizabeth G Klein, Micah Berman
Electronic Nicotine Delivery Systems (ENDS) were introduced into the US market in 2007, and until recently these devices were unregulated at the federal level. In 2014, the US Food and Drug Administration (FDA) published a Notice of Proposed Rulemaking asserting its intention to regulate ENDS and requesting public comments on numerous related issues, including potential limits on the sale of flavored ENDS. This article analyzes key comments submitted to the FDA on the issue of flavor regulation in ENDS and examines the weight and credibility of the evidence presented by both supporters and opponents of regulation...
May 8, 2017: Journal of Health Politics, Policy and Law
https://www.readbyqxmd.com/read/28479174/identification-of-a-defined-linear-epitope-in-the-ospa-protein-of-the-lyme-disease-spirochetes-that-elicits-bactericidal-antibody-responses-implications-for-vaccine-development
#11
Jerilyn R Izac, Lee D Oliver, Christopher G Earnhart, Richard T Marconi
The lipoprotein OspA is produced by the Lyme disease spirochetes primarily in unfed ticks. OspA production is down-regulated by the blood meal and it is not produced in mammals except for possible transient production during late stage infection in patients with Lyme arthritis. Vaccination with OspA elicits antibody (Ab) that can target spirochetes in the tick midgut during feeding and inhibit transmission to mammals. OspA was the primary component of the human LYMErix™ vaccine. LYMErix™ was available from 1998 to 2002 but then pulled from the market due to declining sales as a result of unsubstantiated concerns about vaccination induced adverse events and poor efficacy...
May 31, 2017: Vaccine
https://www.readbyqxmd.com/read/28464141/association-between-academic-medical-center-pharmaceutical-detailing-policies-and-physician-prescribing
#12
Ian Larkin, Desmond Ang, Jonathan Steinhart, Matthew Chao, Mark Patterson, Sunita Sah, Tina Wu, Michael Schoenbaum, David Hutchins, Troyen Brennan, George Loewenstein
Importance: In an effort to regulate physician conflicts of interest, some US academic medical centers (AMCs) enacted policies restricting pharmaceutical representative sales visits to physicians (known as detailing) between 2006 and 2012. Little is known about the effect of these policies on physician prescribing. Objective: To analyze the association between detailing policies enacted at AMCs and physician prescribing of actively detailed and not detailed drugs...
May 2, 2017: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/28459872/forecasting-electric-vehicles-sales-with-univariate-and-multivariate-time-series-models-the-case-of-china
#13
Yong Zhang, Miner Zhong, Nana Geng, Yunjian Jiang
The market demand for electric vehicles (EVs) has increased in recent years. Suitable models are necessary to understand and forecast EV sales. This study presents a singular spectrum analysis (SSA) as a univariate time-series model and vector autoregressive model (VAR) as a multivariate model. Empirical results suggest that SSA satisfactorily indicates the evolving trend and provides reasonable results. The VAR model, which comprised exogenous parameters related to the market on a monthly basis, can significantly improve the prediction accuracy...
2017: PloS One
https://www.readbyqxmd.com/read/28447766/supervised-dosing-with-a-long-acting-opioid-medication-in-the-management-of-opioid-dependence
#14
REVIEW
Rosella Saulle, Simona Vecchi, Linda Gowing
BACKGROUND: Opioid dependence (OD) is an increasing clinical and public health problem worldwide. International guidelines recommend opioid substitution treatment (OST), such as methadone and buprenorphine, as first-line medication treatment for OD. A negative aspect of OST is that the medication used can be diverted both through sale on the black market, and the unsanctioned use of medications. Daily supervised administration of medications used in OST has the advantage of reducing the risk of diversion, and may promote therapeutic engagement, potentially enhancing the psychosocial aspect of OST, but costs more and is more restrictive on the client than dispensing for off-site consumption...
April 27, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28444233/neighborhood-variation-in-the-price-of-cheap-tobacco-products-in-california-results-from-healthy-stores-for-a-healthy-community
#15
Lisa Henriksen, Elizabeth Andersen-Rodgers, Xueying Zhang, April Roeseler, Dennis L Sun, Trent O Johnson, Nina C Schleicher
Background.: Retail marketing surveillance research highlights concerns about lower-priced cigarettes in neighborhoods with a higher proportion of racial/ethnic minorities, but focuses almost exclusively on premium brands. To remedy this gap in the literature, the current study examines neighborhood variation in prices for the cheapest cigarettes and a popular brand of cigarillos in a large statewide sample of licensed tobacco retailers in a low-tax state. Methods.: All 61 local health departments in California trained data collectors to conduct observations in a census of eligible licensed tobacco retailers in randomly selected zip codes (n=7,393 stores, completion rate=91%)...
April 22, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/28438819/essentials-of-essential-oils
#16
Chelsea R Manion, Rebecca M Widder
PURPOSE: Information to guide clinicians in educating and advising patients using or intending to use essential oils for self-administered aromatherapy or other medicinal purposes is presented. SUMMARY: The term essential oils refers to highly concentrated, aromatic oils extracted from plants by steam distillation, hydrodiffusion, or pressure. Market reports indicate strong growth in the use of essential oils in the United States in recent decades. Therapeutic claims made in the marketing of essential oils have led the Food and Drug Administration to caution a number of suppliers...
May 1, 2017: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/28438145/insights-into-the-availability-and-distribution-of-oral-artemisinin-monotherapy-in-myanmar-evidence-from-a-nationally-representative-outlet-survey
#17
Si Thu Thein, Hnin Su Su Khin, Aung Thi
BACKGROUND: The containment of artemisinin resistance in Myanmar, historically an important probable origin and route of anti-malarial resistance to the India sub-continent and beyond, is crucial to global malaria control and elimination. This paper describes what is currently known about the sale and distribution of oral artemisinin monotherapy (AMT) across Myanmar, where this medicine is commonly found. METHODS: A nationally representative 2015 outlet survey was conducted in the private sector, and among community health workers across four geographical domains...
April 25, 2017: Malaria Journal
https://www.readbyqxmd.com/read/28434919/a-review-of-dtca-techniques-appraising-their-success-and-potential-impact-on-medication-users
#18
REVIEW
Zaheer-Ud-Din Babar, Ashna Medina Siraj, Louise Curley
BACKGROUND: Direct-to-consumer advertising (DTCA) has been present in some countries for nearly two decades. Its success and ramifications have been examined but not yet cataloged recently in a comprehensive manner. OBJECTIVE: To review existing literature studies on the topic of DTCA techniques to provide an analysis of the current methods considered by drug marketers to enhance the effect of pharmaceutical product promotion and its success, as well as examine ramifications on the drug use process...
April 12, 2017: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/28420773/are-direct-to-consumer-marketing-and-over-the-counter-sale-of-hearing-aids-beneficial-to-patients-with-hearing-loss-a-provider-s-perspective
#19
Kenneth P Thomas
No abstract text is available yet for this article.
March 2017: North Carolina Medical Journal
https://www.readbyqxmd.com/read/28419459/how-can-we-restrict-the-sale-of-sports-and-energy-drinks-to-children
#20
REVIEW
Gillian Jean
High sugar drinks (HSD) including fruit drinks, soft drinks, sports drinks, and energy drinks, are of no nutritional value and contribute to the burden of dental disease in all age groups. The manufacturers of sports and energy drinks have elected to target children in their marketing campaigns and promote a misleading association between their products, healthy lifestyles and sporting prowess. The WHO has acknowledged that strategies aimed at prevention of dental disease are the only economically viable options for managing the oral health of children in low and middle income countries...
April 17, 2017: Australian Dental Journal
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