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https://www.readbyqxmd.com/read/29225712/a-look-ahead-strategy-for-non-directed-donors-in-kidney-paired-donation
#1
Wen Wang, Mathieu Bray, Peter X-K Song, John D Kalbfleisch
While there is a growing need for kidney transplants to treat end stage kidney disease, the supply of transplantable kidneys is in serious shortage. Kidney paired donation (KPD) programs serve as platforms for candidates with willing but incompatible donors to assess the possibility of exchanging donors, thus opening up new transplant opportunities for these candidates. In recent years, non-directed (or altruistic) donors (NDDs) have been incorporated into KPD programs beginning chains of transplants that benefit many candidates...
December 2017: Statistics in Biosciences
https://www.readbyqxmd.com/read/29225472/18f-fluorodeoxyglucose-uptake-predicts-met-expression-in-lung-adenocarcinoma
#2
Shuxian An, Xiang Zhou, Jianjun Liu, Gang Huang
Objective: MET is a member of the receptor tyrosine kinases. Several MET-targeting inhibitors and antagonistic antibodies have shown promising data in clinical trials of lung adenocarcinoma. Finding noninvasive diagnostic tools to estimate the status of MET is helpful in clinical practice. 18F-fluorodeoxyglucose positron emission tomography/computerized tomography (18F-FDG PET/CT) has been used routinely for the diagnosis and staging of tumors. However, the relationship between MET expression and 18F-FDG uptake has not been investigated yet...
2017: OncoTargets and Therapy
https://www.readbyqxmd.com/read/29224980/factors-responsible-for-the-post-slaughter-loss-of-carcass-and-offal-s-in-abattoirs-in-south-africa
#3
Ishmael Festus Jaja, Borden Mushonga, Ezekiel Green, Voster Muchenje
Global demand for food is surging upward due to the expansion of human population. Hence food production and supply need to double with little or no waste to meet this demand. Food loss at any point in the farm to fork chain inhibits the stability of food security at household and national level. A retrospective (AR) and a post mortem meat inspection (PMMI) study to identify major causes of offal and carcass condemnation was conducted in three abattoirs namely, Adeliade, Queenstown and East London abattoirs represented as AD, QT, and EL respectively...
December 7, 2017: Acta Tropica
https://www.readbyqxmd.com/read/29223964/assessing-stakeholder-perceptions-of-the-acceptability-and-feasibility-of-national-scale-up-for-a-dual-hiv-syphilis-rapid-diagnostic-test-in-malawi
#4
Brandy L Peterson Maddox, Shauntā S Wright, Hazel Namadingo, Virginia B Bowen, Geoffrey A Chipungu, Mary L Kamb
OBJECTIVES: The WHO recommends pregnant women receive both HIV and syphilis testing at their first antenatal care visit, as untreated maternal infections can lead to severe, adverse pregnancy outcomes. One strategy for increasing testing for both HIV and syphilis is the use of point-of-care (rapid) diagnostic tests that are simple, proven effective and inexpensive. In Malawi, pregnant women routinely receive HIV testing, but only 10% are tested for syphilis at their first antenatal care visit...
December 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/29222503/co2-mineralization-and-utilization-using-steel-slag-for-establishing-a-waste-to-resource-supply-chain
#5
Shu-Yuan Pan, Tai-Chun Chung, Chang-Ching Ho, Chin-Jen Hou, Yi-Hung Chen, Pen-Chi Chiang
Both steelmaking via an electric arc furnace and manufacturing of portland cement are energy-intensive and resource-exploiting processes, with great amounts of carbon dioxide (CO2) emission and alkaline solid waste generation. In fact, most CO2 capture and storage technologies are currently too expensive to be widely applied in industries. Moreover, proper stabilization prior to utilization of electric arc furnace slag are still challenging due to its high alkalinity, heavy metal leaching potentials and volume instability...
December 8, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29222365/implementation-of-an-integrated-pharmacy-supply-management-strategy
#6
Lindsey B Amerine, Daniel R Calvert, Ashley L Pappas, Sarah M Lee, John M Valgus, Scott W Savage
PURPOSE: Implementation of an integrated pharmacy supply management strategy is described. SUMMARY: In 2011, the formulary approval process and supply management for oncology medications were independent of each other at an oncology infusion center. Numerous nonformulary medications were kept on hand and reordered based on inventory levels that were established with inadequate usage information, while some formulary agents did not have on-hand inventory levels and had to be reordered on a patient-specific basis, which required paperwork and then a review by drug information staff per institutional policy...
December 15, 2017: American Journal of Health-system Pharmacy: AJHP
https://www.readbyqxmd.com/read/29218304/from-invention-to-innovation-risk-analysis-to-integrate-one-health-technology-in-the-dairy-farm
#7
Andrea Lombardo, Carlo Boselli, Simonetta Amatiste, Simone Ninci, Chiara Frazzoli, Roberto Dragone, Alberto De Rossi, Gerardo Grasso, Alberto Mantovani, Giovanni Brajon
Current Hazard Analysis Critical Control Points (HACCP) approaches mainly fit for food industry, while their application in primary food production is still rudimentary. The European food safety framework calls for science-based support to the primary producers' mandate for legal, scientific, and ethical responsibility in food supply. The multidisciplinary and interdisciplinary project ALERT pivots on the development of the technological invention (BEST platform) and application of its measurable (bio)markers-as well as scientific advances in risk analysis-at strategic points of the milk chain for time and cost-effective early identification of unwanted and/or unexpected events of both microbiological and toxicological nature...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/29215968/food-flows-in-the-uk-the-potential-of-surplus-food-redistribution-to-reduce-waste
#8
Elisa Facchini, Eleni Iacovidou, Jan Gronow, Nikolaos Voulvoulis
The increasing amount of food waste generated as a direct consequence of its excessive production, mismanagement and wasteful behaviours, represents a real challenge in promoting resource efficiency. In the UK, the lack of robust mass flow data hinders both the ability to understand and address food waste challenges, and to devise long-term sustainable prevention strategies. In recognition of these challenges, this paper seeks to: i) provide insights into the UK's annual estimates of food mass flows, including imports, exports, distribution, consumption, surplus food production, and final disposal, and ii) scrutinise the uptake and surplus food redistribution as a potential food waste prevention strategy...
December 7, 2017: Journal of the Air & Waste Management Association
https://www.readbyqxmd.com/read/29212305/cancer-energy-metabolism-shutting-power-off-cancer-factory
#9
REVIEW
Soo-Youl Kim
In 1923, Dr. Warburg had observed that tumors acidified the Ringer solution when 13 mM glucose was added, which was identified as being due to lactate. When glucose is the only source of nutrient, it can serve for both biosynthesis and energy production. However, a series of studies revealed that the cancer cell consumes glucose for biosynthesis through fermentation, not for energy supply, under physiological conditions. Recently, a new observation was made that there is a metabolic symbiosis in which glycolytic and oxidative tumor cells mutually regulate their energy metabolism...
December 7, 2017: Biomolecules & Therapeutics
https://www.readbyqxmd.com/read/29203077/waste-wood-as-bioenergy-feedstock-climate-change-impacts-and-related-emission-uncertainties-from-waste-wood-based-energy-systems-in-the-uk
#10
Mirjam Röder, Patricia Thornley
Considering the urgent need to shift to low carbon energy carriers, waste wood resources could provide an alternative energy feedstock and at the same time reduce emissions from landfill. This research examines the climate change impacts and related emission uncertainties of waste wood based energy. For this, different grades of waste wood and energy application have been investigated using lifecycle assessment. Sensitivity analysis has then been applied for supply chain processes and feedstock properties for the main emission contributing categories: transport, processing, pelletizing, urea resin fraction and related N2O formation...
December 1, 2017: Waste Management
https://www.readbyqxmd.com/read/29202906/managing-food-allergens-in-the-u-k-retail-supply-chain
#11
Michael J Walker, M Hazel Gowland, John Points
The U.K. food and grocery market is highly significant financially and dominated by 10 retailers within a regulated and extremely economically competitive environment. We summarize the approach of U.K. retailers to allergen risk assessment (RA) and risk management (RM) within the U.K. legal framework and explore public visibility of retailers' allergen policies. RA and RM of allergens appear effective in curtailing retail-triggered severe food allergy reactions. However, allergen recalls remain high, precautionary allergen labeling (PAL) remains an area of confusion, and there is no consistent Web-based provision of information for consumers who have allergies...
December 5, 2017: Journal of AOAC International
https://www.readbyqxmd.com/read/29202905/undeclared-food-allergens-and-gluten-in-commercial-food-products-analyzed-by-elisa
#12
Andrew B Do, Sefat E Khuda, Girdhari M Sharma
Undeclared allergen(s) in commercial food products are responsible for many food recalls, as reported by regulatory agencies in various countries, including the United States. Correct allergen labeling practices are essential for the safety of food-allergic consumers. However, this practice may be hindered by the introduction of allergens all along the food supply chain, including unintentionally through cross-contact. To understand the pervasiveness of undeclared allergen(s) in commercial food products, the objective of this review is to summarize the prevalence of undeclared milk, egg, hazelnut, peanut, soy, and gluten as detected by ELISA from previously published surveys...
December 5, 2017: Journal of AOAC International
https://www.readbyqxmd.com/read/29201141/valorization-of-pyrolysis-water-a-biorefinery-side-stream-for-1-2-propanediol-production-with-engineered-corynebacterium-glutamicum
#13
Julian Lange, Felix Müller, Kerstin Bernecker, Nicolaus Dahmen, Ralf Takors, Bastian Blombach
Background: A future bioeconomy relies on the efficient use of renewable resources for energy and material product supply. In this context, biorefineries have been developed and play a key role in converting lignocellulosic residues. Although a holistic use of the biomass feed is desired, side streams evoke in current biorefinery approaches. To ensure profitability, efficiency, and sustainability of the overall conversion process, a meaningful valorization of these materials is needed...
2017: Biotechnology for Biofuels
https://www.readbyqxmd.com/read/29196295/quasi-metagenomics-and-realtime-sequencing-aided-detection-and-subtyping-of-salmonella-enterica-from-food-samples
#14
Ji-Yeon Hyeon, Shaoting Li, David A Mann, Shaokang Zhang, Zhen Li, Yi Chen, Xiangyu Deng
Metagenomics analysis of food samples promises isolation-independent detection and subtyping of foodborne bacterial pathogens in a single workflow. Selective concentration of Salmonella genomic DNA through immunomagnetic separation (IMS) and multiple displacement amplification (MDA) were shown to shorten culture enrichment of Salmonella-spiked raw chicken breast samples by over 12 hours while permitting serotyping and high-fidelity single nucleotide polymorphisms (SNP) typing of the pathogen using short shotgun sequencing reads...
December 1, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/29186934/joint-decision-making-and-the-coordination-of-a-sustainable-supply-chain-in-the-context-of-carbon-tax-regulation-and-fairness-concerns
#15
Zhi Liu, Xiao-Xue Zheng, Ben-Gang Gong, Yun-Miao Gui
Carbon tax regulation and consumers' low-carbon preference act as incentives for firms to abate emissions. Manufacturers can improve product sustainability and retailers can strengthen the promotion of low-carbon products as part of such abatement. Current incomplete rationality also affects product sustainability and low-carbon promotion level. In this context, we consider a supply chain with a manufacturer and a retailer and investigate the impacts of the manufacturer's and the retailer's fairness concerns on their production sustainability level, low-carbon promotion level and profitability...
November 27, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29186883/consumers-in-a-sustainable-food-supply-chain-cosus-understanding-consumer-behavior-to-encourage-food-waste-reduction
#16
Harald Rohm, Marije Oostindjer, Jessica Aschemann-Witzel, Claudia Symmank, Valérie L Almli, Ilona E de Hooge, Anne Normann, Kostas Karantininis
Consumers are directly and indirectly responsible for a significant fraction of food waste which, for a large part, could be avoided if they were willing to accept food that is suboptimal, i.e., food that deviates in sensory characteristics (odd shape, discoloration), or that has a best-before date which is approaching or has passed, but that is still perfectly fine to eat. The choice to accept or discard suboptimal food is taken either before or after purchase (hence, in the retail store or in the household)...
November 27, 2017: Foods (Basel, Switzerland)
https://www.readbyqxmd.com/read/29186857/techno-economic-analysis-of-biofuel-production-from-macroalgae-seaweed
#17
Mohsen Soleymani, Kurt A Rosentrater
A techno-economic evaluation of bioenergy production from macroalgae was carried out in this study. Six different scenarios were examined for the production of different energy products and by-products. Seaweed was produced either via the longline method or the grid method. Final products of these scenarios were either ethanol from fermentation, or electricity from anaerobic digestion (AD). By-products were digestate for AD, and animal feed, or electricity and digestate, for the fermentation pathway. Bioenergy breakeven selling prices were investigated according to the cost components and the feedstock supply chain, while suggestions for potential optimization of costs were provided...
November 26, 2017: Bioengineering
https://www.readbyqxmd.com/read/29186013/improving-the-accessibility-and-efficiency-of-point-of-care-diagnostics-services-in-low-and-middle-income-countries-lean-and-agile-supply-chain-management
#18
REVIEW
Desmond Kuupiel, Vitalis Bawontuo, Tivani P Mashamba-Thompson
Access to point-of-care (POC) diagnostics services is essential for ensuring rapid disease diagnosis, management, control, and surveillance. POC testing services can improve access to healthcare especially where healthcare infrastructure is weak and access to quality and timely medical care is a challenge. Improving the accessibility and efficiency of POC diagnostics services, particularly in resource-limited settings, may be a promising route to improving healthcare outcomes. In this review, the accessibility of POC testing is defined as the distance/proximity to the nearest healthcare facility for POC diagnostics service...
November 29, 2017: Diagnostics
https://www.readbyqxmd.com/read/29185230/molecular-epidemiology-of-rotavirus-strains-in-under-five-children
#19
Yunus Bulut, Gülgün Yenişehirli, Rıza Durmaz
OBJECTIVES: To determine the prevalence and genotype distribution of rotaviruses in children presenting to authors' hospital in Middle Black Sea region of Turkey. The results may supply important information about vaccine studies in Turkey. METHODS: Rotavirus antigen was detected by latex agglutination test and rotavirus RNA was detected by RT-PCR test. On the other hand, rotavirus positive samples were genotyped by semi-nested multiplex polymerase chain reaction...
November 29, 2017: Indian Journal of Pediatrics
https://www.readbyqxmd.com/read/29182545/detection-of-abrin-holotoxin-using-novel-monoclonal-antibodies
#20
Xiaohua He, Stephanie Patfield, Luisa W Cheng, Larry H Stanker, Reuven Rasooly, Thomas A McKeon, Yuzhu Zhang, David L Brandon
Abrin, a member of the ribosome-inactivating protein family, is produced by the Abrus precatorius plant. Having the potential to pose a severe threat to both human and animal health, abrin is classified as a Select Agent by the U.S. Department of Health and Human Services. However, an immunoassay that is specific for intact abrin holotoxin has not yet been reported. In this study, seven new monoclonal antibodies (mAbs), designated as Abrin-1 through Abrin-7 have been developed. Isotyping analyses indicate these mAbs have IgG1, IgG2a, or IgG2b heavy-chains and kappa light-chains...
November 28, 2017: Toxins
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