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tinea capitis

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https://www.readbyqxmd.com/read/28101694/relationship-between-phenotypic-and-genotypic-characteristics-of-trichophyton-mentagrophytes-strains-isolated-from-patients-with-dermatophytosis
#1
I Dhib, I Khammari, A Yaacoub, F Hadj Slama, M Ben Saïd, R Zemni, A Fathallah
According to epidemiological, clinical and mycological criteria, it has long been admitted that the Trichophyton mentagrophytes species includes two varieties: a zoophilic variety (var. mentagrophytes) and an anthropophilic variety (var. interdigitale) that involve the upper and the lower part of the body, respectively. The further application of molecular techniques to the characterization of dermatophyte strains showed that this classification is unreliable. The aim of our study was to assess the usefulness of PCR-RFLP (restriction fragment length polymorphism) and sequencing in the characterization of T...
January 18, 2017: Mycopathologia
https://www.readbyqxmd.com/read/28099533/tinea-capitis-caused-by-trichophyton-rubrum-mimicking-favus
#2
Alan S Boyd
Favus is an uncommon form of tinea capitis (TC) currently seen in geographic areas with poor sanitation and limited access to health care such as emerging nations. Several variants of this condition have been described including one exhibiting a plaque composed of parchmentlike material. The makeup of this plaque has not been described. Tinea capitis is rare in adults, particularly when the infectious agent is Trichophyton rubrum, and affected patients often exhibit comorbidities associated with diminished immune surveillance...
December 2016: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/28088394/tinea-in-tots-cases-and-literature-review-of-oral-antifungal-treatment-of-tinea-capitis-in-children-under-2-years-of-age
#3
John G Zampella, Shawn G Kwatra, Jaime Blanck, Bernard Cohen
No abstract text is available yet for this article.
January 12, 2017: Journal of Pediatrics
https://www.readbyqxmd.com/read/28087021/ultraviolet-dermoscopy-for-the-diagnosis-of-tinea-capitis
#4
Jiaoqing Tang, Xin Ran, Yuping Ran
No abstract text is available yet for this article.
February 2017: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/28050591/trichophyton-rubrum-tinea-capitis-in-an-hiv-positive-patient-with-generalized-dermatophytosis
#5
Caely A Hambro, Natalie C Yin, Christine Yang, Sameera Husain, David N Silvers, Marc E Grossman
No abstract text is available yet for this article.
January 2017: JAAD Case Reports
https://www.readbyqxmd.com/read/28040418/-trichophyton-tonsurans-associated-with-non-albicans-candida-species-in-hands-onychomycosis-about-a-moroccan-case
#6
S Kouara, B Ait Hlilou, A Abbadi, H Khalki, I Benbella, K Lahmadi, M Er-Rami
INTRODUCTION: Trichophyton tonsurans is an anthropophilic dermatophyte, frequent in the USA and in Asia where it is responsible for causing tinea capitis. At present, we attend an emergence of this species in certain regions where it was not or little met. Here, we report a case of onychomycosis of the hand due to T. tonsurans associated with non-albicans Candida species at an adult woman. OBSERVATION: The patient is a 62-year-old woman, with hypertension and diabetes...
December 28, 2016: Journal de Mycologie Médicale
https://www.readbyqxmd.com/read/27956429/in-vitro-antifungal-susceptibility-profile-of-12-antifungal-drugs-against-55-trichophyton-schoenleinii-isolated-from-tinea-capitis-favosa-in-iran-turkey-and-china
#7
Shuwen Deng, Saham Ansari, Macit Ilkit, Haleh Rafati, Mohammad T Hedayati, Mojtaba Taghizadeh-Armaki, Ayatollah Nasrollahi-Omran, Ali Tolooe, Ping Zhan, Wanqing Liao, Henrich A van der Lee, Paul E Verweij, Seyedmojtaba Seyedmousavi
Trichophyton schoenleinii is an anthropophilic dermatophyte mainly causing tinea favosa of the scalp in certain regions of the world, especially Africa and Asia. We investigated the in vitro susceptibilities of 55 T. schoenleinii collected over the last thirty years from Iran, Turkey and China against 12 antifungals using the CLSI broth-microdilution method. Our results revealed that terbinafine and ketoconazole were the most potent antifungal agents among those tested, independent of the geographical regions isolated...
12, 2016: Antimicrobial Agents and Chemotherapy
https://www.readbyqxmd.com/read/27915299/cathelicidin-ll-37-level-in-the-scalp-hair-of-patients-with-tinea-capitis
#8
Nagwa H Abdelaal, Laila A Rashed, Sahar Y Ibrahim, Mona H Abd El Halim, Noha Ghoneim, Noha A Saleh, Marwah A Saleh
Antimicrobial peptides (AMPs) are considered an important first line of defense against pathogens. Cathelicidin LL-37 was upregulated in response to fungal infection. In this work we aimed to evaluate cathelicidin LL-37 in the hair of tinea capitis and compare it to normal controls. Hair samples were collected from 30 children and 30 controls aged from 2 to10 years old, and the level of cathelicidin LL-37 in the hair was detected by quantitative real-time PCR. The 30 patients were further subdivided into three subgroups according to their clinical type...
December 2, 2016: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/27904054/epidemiology-of-dermatophytoses-in-crete-greece
#9
Sofia Maraki, Viktoria Eirini Mavromanolaki
Dermatophytoses are among the most frequently diagnosed skin infections worldwide. However, the distribution of pathogenic species and the predominating anatomical sites of infection vary with geographical location and change over time. The aim of this study was to determine the epidemiological and aetiological factors of dermatophytoses in Crete, Greece over the last 5-year period (2011-2015) and their incidence in relation to the gender and the age of the patients. We compared our findings with those previously reported from the same area and from other parts of the world...
2016: Medical Mycology Journal
https://www.readbyqxmd.com/read/27892847/international-adoption-from-ethiopia-an-overview-of-the-health-status-at-arrival-in-belgium
#10
Lydia Van Kesteren, Marek Wojciechowski
BACKGROUND: Ethiopia is a densely populated country with a fast growing economy. Still socioeconomic and health issues render many children parentless. One thousand and twenty eight Ethiopian children have been adopted in Belgium from September 2005 to September 2015. Little has been published about their health status at arrival. METHODS: Three hundred and fifteen children adopted from Ethiopia were clinically evaluated at the Institute of Tropical Medicine in Antwerp from 1 January 2008 until 31 December 2014...
November 28, 2016: Acta Clinica Belgica
https://www.readbyqxmd.com/read/27887809/an-estimation-of-burden-of-serious-fungal-infections-in-france
#11
J-P Gangneux, M-E Bougnoux, C Hennequin, C Godet, J Chandenier, D W Denning, B Dupont
OBJECTIVE OF THE STUDY: An estimation of burden of serious fungal diseases in France is essential data to inform public health priorities on the importance of resources and research needed on these infections. In France, precise data are available for invasive fungal diseases but estimates for several other diseases such as chronic and immunoallergic diseases are by contrast less known. MATERIALS AND METHODS: A systematic literature search was conducted using the Web of Science Platform...
December 2016: Journal de Mycologie Médicale
https://www.readbyqxmd.com/read/27881134/low-dose-radiation-risks-for-women-surviving-the-a-bombs-in-japan-generalized-additive-model
#12
Greg Dropkin
BACKGROUND: Analyses of cancer mortality and incidence in Japanese A-bomb survivors have been used to estimate radiation risks, which are generally higher for women. Relative Risk (RR) is usually modelled as a linear function of dose. Extrapolation from data including high doses predicts small risks at low doses. Generalized Additive Models (GAMs) are flexible methods for modelling non-linear behaviour. METHODS: GAMs are applied to cancer incidence in female low dose subcohorts, using anonymous public data for the 1958 - 1998 Life Span Study, to test for linearity, explore interactions, adjust for the skewed dose distribution, examine significance below 100 mGy, and estimate risks at 10 mGy...
November 24, 2016: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/27843914/trichoscopy-of-focal-alopecia-in-children-new-trichoscopic-findings-hair-bulbs-arranged-radially-along-hair-bearing-margins-in-aplasia-cutis-congenita
#13
Adriana Rakowska, Małgorzata Maj, Małgorzata Zadurska, Joanna Czuwara, Olga Warszawik-Henzel, Małgorzata Olszewska, Lidia Rudnicka
PURPOSE: To establish whether trichoscopy can be useful in the differential diagnosis of patchy alopecia in children. PROCEDURES: The study was a retrospective analysis (2012-2015) and included 68 patients under 6 years of age. The inclusion criteria were age and the presence of 1-3 alopecia patches. A total of 124 alopecia patches were examined with the use of a videodermoscope: 102 alopecia areata, 8 tinea capitis, 6 trichotillomania, 3 temporal triangular alopecia and 5 aplasia cutis congenita...
September 2016: Skin Appendage Disorders
https://www.readbyqxmd.com/read/27816294/systemic-antifungal-therapy-for-tinea-capitis-in-children-an-abridged-cochrane-review
#14
Xiaomei Chen, Xia Jiang, Ming Yang, Cathy Bennett, Urbà González, Xiufang Lin, Xia Hua, Siliang Xue, Min Zhang
BACKGROUND: The comparative efficacy and safety profiles of systemic antifungal drugs for tinea capitis in children remain unclear. OBJECTIVE: We sought to assess the effects of systemic antifungal drugs for tinea capitis in children. METHODS: We used standard Cochrane methodological procedures. RESULTS: We included 25 randomized controlled trials with 4449 participants. Terbinafine and griseofulvin had similar effects for children with mixed Trichophyton and Microsporum infections (risk ratio 1...
November 2, 2016: Journal of the American Academy of Dermatology
https://www.readbyqxmd.com/read/27783316/the-changing-face-of-dermatophytic-infections-worldwide
#15
REVIEW
Ping Zhan, Weida Liu
Dermatophytes evolve along with the geography and socioeconomic conditions. Epidermophyton floccosum, Microsporum audouinii and Trichophyton schoenleinii acted as the major pathogens of superficial fungal diseases 100 years ago, but their frequency decreased dramatically since the middle of the twentieth century and they are limited to some less-developed countries nowadays; meanwhile, frequency of Trichophyton rubrum, Trichophyton interdigitale, Trichophyton tonsurans and Microsporum canis increased gradually, and these fungi have become the major species globally...
October 25, 2016: Mycopathologia
https://www.readbyqxmd.com/read/27760831/identification-of-the-causative-dermatophyte-of-tinea-capitis-in-children-attending-mbarara-regional-referral-hospital-in-uganda-by-pcr-elisa-and-comparison-with-conventional-mycological-diagnostic-methods
#16
Cornelia Wiegand, Peter Mugisha, Grace K Mulyowa, Peter Elsner, Uta-Christina Hipler, Yvonne Gräser, Silke Uhrlaß, Pietro Nenoff
Tinea capitis is a dermatophyte infection common among prepubertal children in sub-Saharan Africa and mainly caused by Trichophyton and Microsporum species. Accurate identification is challenging as conventional methods like culture and microscopy are slow and mostly based on morphological characteristics, which make them less sensitive and specific. Modern molecular methods, like polymerase chain reaction (PCR) assays, are gaining acceptance and are quick as well as accurate. The aim of this study was to investigate the clinical patterns of tinea capitis and to accurately identify the most common causative dermatophytes affecting the scalps of children aged 1 to 16 years attending the Skin Clinic at Mbarara University of Science and Technology (MUST), Mbarara, Uganda, East Africa, using both conventional mycological methods and PCR-ELISA for detection of dermatophyte DNA...
October 19, 2016: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/27760791/tert-promoter-mutations-a-genetic-signature-of-benign-and-malignant-thyroid-tumours-occurring-in-the-context-of-tinea-capitis-irradiation
#17
Paula Boaventura, Rui Batista, Ana Pestana, Marta Reis, Adélia Mendes, Catarina Eloy, Manuel Sobrinho-Simões, Paula Soares
OBJECTIVE: The aim of this study is to evaluate the frequency and molecular characteristics of TERTp mutations in thyroid adenomas and carcinomas occurring in the low-dose radiation exposure tinea capitis setting. DESIGN AND METHODS: Twenty-seven patients with 34 well-differentiated thyroid carcinomas and 28 patients with 29 follicular adenomas diagnosed in a Portuguese tinea capitis cohort were studied. Blood samples were obtained from all the patients. Screening for TERTp mutations was performed by PCR amplification followed by Sanger sequencing...
January 2017: European Journal of Endocrinology
https://www.readbyqxmd.com/read/27744309/continuous-increase-of-trichophyton-tonsurans-as-a-cause-of-tinea-capitis-in-the-urban-area-of-paris-france-a-5-year-long-study
#18
Maud Gits-Muselli, Mazouz Benderdouche, Samia Hamane, Anselme Mingui, Martine Feuilhade de Chauvin, Nicolas Guigue, Marie-Quitterie Picat, Emmanuelle Bourrat, Antoine Petit, Martine Bagot, Alexandre Alanio, Stéphane Bretagne
Tinea capitis (TC) is a highly contagious fungal infection of the scalp due to dermatophytes in children. To obtain information on the epidemiology of TC in the urban area of Paris, we analysed the microbiological results of 3090 patients seen with suspected TC from October 2010 to September 2015 at Saint Louis hospital, Paris, France. A peak of TC was observed in 3-6 year-old children, followed by a progressive decrease until 16 years of age. Of the 1311 positive cultures, 95% (1246) yielded one of the three anthropophilic species [Trichophyton tonsurans (33...
October 14, 2016: Medical Mycology: Official Publication of the International Society for Human and Animal Mycology
https://www.readbyqxmd.com/read/27696388/the-kerion-an-angry-tinea-capitis
#19
Ann M John, Robert A Schwartz, Camila K Janniger
Tinea capitis has a high incidence with a global changing pathogen distribution, making this condition a public health concern around the world. As the infection is initially asymptomatic, it is easily spread. Moreover, it is present in many fomites, including hairbrushes, pillows, and bedding. Prompt recognition and treatment is necessary for kerion, an inflammatory subtype characterized by tender boggy plaques with purulent drainage. Kerion is usually associated with infection by zoophilic dermatophytes, although other sources have been described...
October 1, 2016: International Journal of Dermatology
https://www.readbyqxmd.com/read/27662210/il6-174-g-c-polymorphism-rs1800795-association-with-late-effects-of-low-dose-radiation-exposure-in-the-portuguese-tinea-capitis-cohort
#20
Paula Boaventura, Cecília Durães, Adélia Mendes, Natália Rios Costa, Inês Chora, Sara Ferreira, Emanuel Araújo, Pedro Lopes, Gilberto Rosa, Pedro Marques, Paulo Bettencourt, Inês Oliveira, Francisco Costa, Isabel Ramos, Maria José Teles, João Tiago Guimarães, Manuel Sobrinho-Simões, Paula Soares
Head and neck cancers, and cardiovascular disease have been described as late effects of low dose radiation (LDR) exposure, namely in tinea capitis cohorts. In addition to radiation dose, gender and younger age at exposure, the genetic background might be involved in the susceptibility to LDR late effects. The -174 G>C (rs1800795) SNP in IL6 has been associated with cancer and cardiovascular disease, nevertheless this association is still controversial. We assessed the association of the IL6-174 G>C SNP with LDR effects such as thyroid carcinoma, basal cell carcinoma and carotid atherosclerosis in the Portuguese tinea capitis cohort...
2016: PloS One
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