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https://www.readbyqxmd.com/read/28643492/human-papillomavirus-genotype-distribution-among-18-815-women-in-13-korean-cities-and-relationship-with-cervical-cytology-findings
#1
Eun Hee Nah, Seon Cho, Suyoung Kim, Han Ik Cho
BACKGROUND: The prevalence and genotype distribution of Human papillomavirus (HPV) infection vary depending on geographical region and the immunity provided by vaccines. This study aimed to clarify the recent prevalence and genotype distribution of HPV according to age and cervical cytology findings in Korea. METHODS: This study included 18,815 health examinees that underwent cervical cytology and HPV genotyping tests at 16 centers of Korean Association of Health Promotion in 13 cities in Korea, between January 2014 and October 2015...
September 2017: Annals of Laboratory Medicine
https://www.readbyqxmd.com/read/28619772/cost-effectiveness-of-hpv-based-cervical-cancer-screening-in-the-public-health-system-in-nicaragua
#2
Nicole G Campos, Mercy Mvundura, Jose Jeronimo, Francesca Holme, Elisabeth Vodicka, Jane J Kim
OBJECTIVES: To evaluate the cost-effectiveness of human papillomavirus (HPV) DNA testing (versus Papanicolaou (Pap)-based screening) for cervical cancer screening in Nicaragua. DESIGN: A previously developed Monte Carlo simulation model of the natural history of HPV infection and cervical cancer was calibrated to epidemiological data from Nicaragua. Cost data inputs were derived using a micro-costing approach in Carazo, Chontales and Chinandega departments; test performance data were from a demonstration project in Masaya department...
June 15, 2017: BMJ Open
https://www.readbyqxmd.com/read/28587376/clinical-progress-of-human-papillomavirus-genotypes-and-their-persistent-infection-in-subjects-with-atypical-squamous-cells-of-undetermined-significance-cytology-statistical-and-latent-dirichlet-allocation-analysis
#3
Yee Suk Kim, Sungin Lee, Nansu Zong, Jimin Kahng
The present study aimed to investigate differences in prognosis based on human papillomavirus (HPV) infection, persistent infection and genotype variations for patients exhibiting atypical squamous cells of undetermined significance (ASCUS) in their initial Papanicolaou (PAP) test results. A latent Dirichlet allocation (LDA)-based tool was developed that may offer a facilitated means of communication to be employed during patient-doctor consultations. The present study assessed 491 patients (139 HPV-positive and 352 HPV-negative cases) with a PAP test result of ASCUS with a follow-up period ≥2 years...
June 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28580567/cytohistological-discrepancies-of-cervico-vaginal-smears-and-hpv-status
#4
İbrahim Alanbay, Mustafa Öztürk, Fahri Burçin Fıratlıgil, Kazım Emre Karaşahin, Müfit Cemal Yenen, Serkan Bodur
OBJECTIVES: Discrepancies between abnormal cervical cytology or high-risk human papillomavirus (HR-HPV) status (cytolo-gy negative/HPV positive) and subsequent histological findings are a common occurrence. After using co-testing, the dis-crepancies between the HR-HPV status and cervical cytology have become an issue. In this study, we aimed to determine the characteristics of women with a discrepancy between histology and cytology/HR-HPV status, in terms of diagnosis, review and identification...
2017: Ginekologia Polska
https://www.readbyqxmd.com/read/28535400/comparison-of-the-cervista-hpv-hr-test-and-luminex-xmap-technology-for-the-diagnosis-of-cervical-intraepithelial-neoplasia
#5
Pei-Yu Zhao, Hui-Ci Jiang, Yue Li, Jin-Bo Wang, Ting-Ting Zhang, Cheng-Hua Liu, Li-Wen Song, Jia-Jing Cheng
OBJECTIVES: This study was designed to compare the Cervista high risk (HR) human papillomavirus (HPV) test with Luminex XMAP technology for the detection of the relationship between HPV infection and cervical intraepithelial neoplasia. METHODS: In total, 3280 patients in a cervical specialty clinic were divided into two groups for either Cervista (1855 patients) or Luminex (1425 patients). Subsequent colposcopy examinations were performed in 1270 women with cytologic results showing ASCUS or higher level lesions...
May 16, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28529583/evaluation-of-microrna-205-expression-as-a-potential-triage-marker-for-patients-with-low-grade-squamous-intraepithelial-lesions
#6
Hong Xie, Ingrid Norman, Anders Hjerpe, Tomislav Vladic, Catharina Larsson, Weng-Onn Lui, Ellinor Östensson, Sonia Andersson
High-risk human papillomavirus (HPV) testing is a recommended triage approach for females with atypical squamous cells of undetermined significance (ASCUS), but due to its poor specificity this approach is not recommended for patients with low-grade squamous intraepithelial lesions (LSIL). The objective of the current study was to determine microRNA (miR)-205 expression levels in liquid-based cytology (LBC) samples, and evaluate their ability to predict cervical intraepithelial neoplasia grade 2/3 or worse (CIN2/3+) in females with minor cytological abnormalities...
May 2017: Oncology Letters
https://www.readbyqxmd.com/read/28521328/assessment-of-100-rapid-review-as-an-effective-tool-for-internal-quality-control-in-cytopathological-services
#7
José Queiroz Filho, Janaina Cristiana de Oliveira Crispim Freitas, Daliana Caldas Pessoa, José Eleutério Júnior, Paulo César Giraldo, Ana Katherine Gonçalves
OBJECTIVE: The aim of this study was to evaluate the 100% rapid review (100%-RR) as an effective tool for internal quality control (IQC) in gynecological cytopathology services. STUDY DESIGN: A total of 8,677 swabs were analyzed; the negative results were submitted to 100%-RR. Divergent cases were discussed in a consensus meeting to reach a conclusion on the final diagnosis. The data were entered into SAS statistical software, and the agreement of the 100%-RR results with the final diagnosis was tested with the weighted kappa statistic...
2017: Acta Cytologica
https://www.readbyqxmd.com/read/28511636/hpv-prevalence-and-type-distribution-in-cypriot-women-with-cervical-cytological-abnormalities
#8
George Krashias, Dana Koptides, Christina Christodoulou
BACKGROUND: Human papillomavirus (HPV) is the most common sexually transmitted agent, and it can cause cervical lesions and cancer in females. Currently, information regarding the prevalence of HPV in Cyprus is lacking. The aim of this study was to evaluate the HPV type-specific prevalence in 596 women, aged 19-65 years, with cytological abnormalities. Additionally, in a subset of 348 women for whom cytology results of the Pap test were available, the association between HPV infection and cervical disease was investigated...
May 16, 2017: BMC Infectious Diseases
https://www.readbyqxmd.com/read/28468038/-sorting-role-of-p16-ink4a-ki-67-double-immunostaining-in-the-cervical-cytology-specimens-of-ascus-and-lsil-cases
#9
J Yu, H T Zhu, J J Zhao, J Z Su, Y D Xia
Objective: To investigate the sorting effect of p16(INK4a)/Ki-67 double immunostaining method in patients with atypical squamous cells of undetermined significance (ASCUS) or low-grade squamous intraepithelial lesion (LSIL) cytology results. Methods: Four-hundred and twenty cases collected during April 2014 to February 2015 of cervical cytology of ASCUS (n=318) and LSIL (n=102) were selected, and residual liquid-based cytology specimens were used for p16(INK4a)/Ki-67 double immunostaining. The sensitivity and specificity of the detection of cervical precancerous lesions and cervical cancer were calculated, and the results were compared with high risk HPV...
May 8, 2017: Zhonghua Bing Li Xue za Zhi Chinese Journal of Pathology
https://www.readbyqxmd.com/read/28445270/pooled-analysis-on-the-necessity-of-random-4-quadrant-cervical-biopsies-and-endocervical-curettage-in-women-with-positive-screening-but-negative-colposcopy
#10
Shang-Ying Hu, Wen-Hua Zhang, Shu-Min Li, Nan Li, Man-Ni Huang, Qin-Jing Pan, Xun Zhang, Ying Han, Fang-Hui Zhao, Wen Chen, You-Lin Qiao
Controversy remains over whether random cervical biopsies and endocervical curettage (ECC) should be used in women with positive screening but negative colposcopy. Our paper aims to determine the indications for random biopsies and ECC among these screened positive women.Three thousand two hundred thirteen women with any positive screening test result but negative colposcopy, who received random 4-quadrant biopsies, were pooled from 17 population-based cervical cancer screening studies done in China from 1999 to 2008...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28436211/primary-hpv-testing-verification-a-retrospective-ad-hoc-analysis-of-screening-algorithms-on-women-doubly-tested-for-cytology-and-hpv
#11
Jessica Tracht, Allison Wrenn, Isam-Eldin Eltoum
BACKGROUND: To evaluate human papillomavirus (HPV) testing as a primary screening tool, we retrospectively analyzed data comparing (1) HPV testing to the algorithms of the ATHENA Study: (2) cytology alone, (3) cytology with ASCUS triage in women 25-29 and (4) cotesting ≥ 30 or (5) cotesting ≥ 25. METHODS: We retrospectively analyzed data from women tested with both cytology and HPV testing from 2010 to 2013. Cumulative risk (CR) for CIN3+ was calculated...
April 23, 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28431558/epidemiology-and-genotype-distribution-of-human-papillomavirus-hpv-in-southwest-china-a-cross-sectional-five-years-study-in-non-vaccinated-women
#12
Yishu Tang, Lan Zheng, Shuangshuang Yang, Bing Li, Huiting Su, Li-Ping Zhang
BACKGROUND: Large-size data on type-specific HPV prevalence in Southwest China are required to estimate the cervical cancer burden in the country and to prepare for HPV-based cervical screening program and further HPV vaccination of China. This HPV study is a pooled analysis of data from five years in Chongqing of China, which is cross-sectional in design using data collecting. RESULTS: The positivity of HPV was 26.2% (10542/40311), single type was 25.7% (10360/40311), multiple type was 8...
April 21, 2017: Virology Journal
https://www.readbyqxmd.com/read/28409592/repeat-cytology-within-six-months-equals-colposcopy-for-younger-women-with-ascus-or-lsil
#13
Linda M Speer
No abstract text is available yet for this article.
April 1, 2017: American Family Physician
https://www.readbyqxmd.com/read/28365936/new-software-for-collecting-data-from-the-organized-cervical-cancer-screening-program-in-serbia-are-we-on-the-threshold-of-a-new-screening-registry-a-multicentric-study
#14
Tamara Naumovic, Vesna Lakic, Ana Jovicevic, Dragan Ilic, Predrag Milosevic, Vesna Stevic-Gajic, Ana Antonijevic, Nada Milovanovic, Ivica Magdic, Rajko Koricanac, Sasa Malkov, Igor Grkavac, Milos Mihajlovic, Slavisa Djuricic, Branislava Zivkovic, Uros Stegic, Zorka Milovanovic, Dejan Opric, Marija Knezevic, Verica Jovanovic, Zoran Todorovic, Dusan Todorovic
PURPOSE: The purpose of this study was to present the Screening Registry and the results of organized cervical cancer screening program (OCCSP) in the Republic of Serbia using a database made as an output model, linked with the Screening Registry. METHODS: Data were respectively collected over a onemonth period from 3 state primary health care centers (and related hospitals/clinical center) in central Serbia in which OCCSP was conducted. The sample consisted of women of the target population (25 to 64 years old) who responded the call for Pap test...
January 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/28364788/the-clinical-research-of-thinprep-cytology-test-tct-combined-with-hpv-dna-detection-in-screening-cervical-cancer
#15
Y Liu, L Zhang, G Zhao, L Che, H Zhang, J Fang
Our objective is to explore the clinical value of thinprep cytologic test (TCT) combined with HPV-DNA detection in screening cervical cancer. 420 cervical cancer patients admitted in our hospital between April, 2011-April, 2014 were selected. All patients received TCT and HPV-DNA detection, and cervical tissue biopsy was used to confirm the diagnosis. TCT screening results showed that there were 175 patients were >ASCUS and the positive rate was 41.7%, histopathological screening showed that there were 199 patients were ≥cervical intraepithelial neoplasia (CIN) I and the positive rate was 47...
February 28, 2017: Cellular and Molecular Biology
https://www.readbyqxmd.com/read/28342244/the-utility-of-pap-cell-block-preparations-with-liqui-prep%C3%A2-cell-pellets-to-clarify-the-cytological-diagnosis-of-atypical-squamous-cells-of-undetermined-significance-and-atypical-glandular-cells
#16
Nicholas B George, Jashua Haddad Baldassari, Digno A Pérez Taveras, María José Fernández, María Concepción Robledo
OBJECTIVE: Atypical squamous cells of undetermined significance (ASCUS) and atypical glandular cells (AGC) reflect cellular abnormalities insufficient for clear diagnosis. We used cell pellets obtained from liquid-based cytology (LBC) to prepare cell blocks (CB) and clarify the initial diagnosis of ASCUS and AGC. STUDY DESIGN: A total of 393 CBs with initial diagnosis of ASCUS or AGC were processed. Of those, 305 of the ASCUS and 20 of the AGC had adequate specimens...
June 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28337594/diagnostic-accuracy-of-high-risk-hpv-dna-genotyping-for-primary-cervical-cancer-screening-and-triage-of-hpv-positive-women-compared-to-cytology-preliminary-results-of-the-pipavir-study
#17
Kimon Chatzistamatiou, Theodoros Moysiadis, Eleftherios Angelis, Andreas Kaufmann, Alkmini Skenderi, Pidder Jansen-Duerr, Irini Lekka, Vasilis Kilintzis, Stamatia Angelidou, Evangelia Katsiki, Ingke Hagemann, Athena Tsertanidou, Isabel Koch, Oliver Boecher, Erwin Soutschek, Nikolaos Maglaveras, Theodoros Agorastos
PURPOSE: The purpose of the presented PIPAVIR (persistent infections with human papillomaviruses; http://www.pipavir.com ) subanalysis is to assess the performance of high-risk (hr) HPV-DNA genotyping as a method of primary cervical cancer screening and triage of HPV positive women to colposcopy compared to liquid-based cytology (LBC) in an urban female population. METHODS: Women, aged 30-60, provided cervicovaginal samples at the Family-Planning Centre, Hippokratio Hospital of Thessaloniki, Greece, and the Department of Gynecology and Obstetrics in Mare Klinikum, Kiel, Germany...
May 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28255767/follow-up-in-women-with-biopsy-diagnosis-of-cervical-low-grade-squamous-intraepithelial-lesion-lsil-how-long-should-it-be
#18
Andrea Ciavattini, Nicolò Clemente, Dimitrios Tsiroglou, Francesco Sopracordevole, Matteo Serri, Giovanni Delli Carpini, Maria Papiccio, Paolo Cattani
AIM: To analyse the regression rate and the risk of persistence or progression of the lesions in women with a histopathological diagnosis of cervical low-grade squamous intraepithelial lesion (LSIL). MATERIALS AND METHODS: Retrospective cohort study of women with biopsy diagnosis of cervical LSIL, from January 2010 to December 2013. After the initial diagnosis of LSIL, all the women underwent scheduled follow-up examinations with cytology every 6 months for 2 years and an HPV test after 1 year...
March 3, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28247516/introduction-of-liquid-based-cytology-and-human-papillomavirus-testing-in-cervical-cancer-screening-in-luxembourg
#19
Ardashel Latsuzbaia, Gaëtan Hebette, Marc Fischer, Marc Arbyn, Steven Weyers, Philippe Vielh, Fernando Schmitt, Joël Mossong
BACKGROUND: In 2014, liquid-based cytology with HPV triage replaced conventional cytology. The aim of our study was to compare conventional and liquid-based cytology (LBC), estimate the prevalence of abnormal cervical cytology and high risk HPV (hrHPV) infection and their correlation, among screened women in Luxembourg. METHODS: Between the first January 2013 and 31st December 2015, 315,868 cervical samples from 150,815 women (mean age 42.2 years) were investigated by the national cytology laboratory...
May 2017: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/28229961/neurospora-tetrasperma-crosses-heterozygous-for-hybrid-translocation-strains-produce-rare-eight-spored-asci-bearing-heterokaryotic-ascospores
#20
Durgadas P Kasbekar, Selvam Rekha
During ascogenesis in Neurospora, the ascospores are partitioned at the eight-nucleus stage that follows meiosis and a post-meiotic mitosis, and the ascospores that form in eight-spored asci are usually homokaryotic. We had previously created novel TNt strains by introgressing four Neurospora crassa insertional translocations (EB4, IBj5, UK14-1, and B362i) into N. tetrasperma. We now show that crosses of all the TNt strains with single-mating-type derivatives of the standard N. tetrasperma pseudohomothallic strain 85 (viz...
March 2017: Journal of Biosciences
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