keyword
https://read.qxmd.com/read/37530362/anaplastic-undifferentiated-carcinoma-of-pancreas-an-uncommon-variant-diagnosed-on-endoscopic-guided-fine-needle-aspiration
#21
Md Ali Osama, Pooja Bakshi, Kusum Verma
Anaplastic carcinoma of pancreas (ACP) are rare pancreatic neoplasms. They are well known to be associated with more aggressive tumor behavior and less favorable prognosis than usual pancreatic ductal adenocarcinoma. Endoscopic-guided fine needle aspiration (EUS-FNA) is now a widely accepted modality in diagnosis of pancreatic lesions. However, only a few reports are available describing cytological features of anaplastic carcinoma. Here, we report two cases of ACP diagnosed on EUS-FNA.
2023: Indian Journal of Pathology & Microbiology
https://read.qxmd.com/read/37522250/simultaneous-establishment-of-pancreatic-cancer-organoid-and-cancer-associated-fibroblast-using-a-single-pass-endoscopic-ultrasound-guided-fine-needle-biopsy-specimen
#22
JOURNAL ARTICLE
Seokhwi Kim, Kyoung Jin Woo, Chan Mo Yang, So Hyun Park, Jae Chul Hwang, Byung Moo Yoo, Jin Hong Kim, Dakeun Lee, Min Jae Yang
Considering the critical roles of cancer-associated fibroblasts (CAFs) in pancreatic cancer, recent studies have attempted to incorporate stromal elements into organoid models to recapitulate the tumor microenvironment. This study aimed to evaluate the feasibility of patient-derived organoid (PDO) and CAF cultures by using single-pass endoscopic ultrasound-guided fine-needle biopsy (EUS-FNB) samples from prospectively enrolled pancreatic cancer patients. The obtained samples were split into two portions for PDO and CAF cultures...
July 31, 2023: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://read.qxmd.com/read/37455599/a-deep-learning-model-using-hyperspectral-image-for-eus-fna-cytology-diagnosis-in-pancreatic-ductal-adenocarcinoma
#23
JOURNAL ARTICLE
Xianzheng Qin, Minmin Zhang, Chunhua Zhou, Taojing Ran, Yundi Pan, Yingjiao Deng, Xingran Xie, Yao Zhang, Tingting Gong, Benyan Zhang, Ling Zhang, Yan Wang, Qingli Li, Dong Wang, Lili Gao, Duowu Zou
BACKGROUND AND AIMS: Endoscopic ultrasonography-guided fine-needle aspiration/biopsy (EUS-FNA/B) is considered to be a first-line procedure for the pathological diagnosis of pancreatic cancer owing to its high accuracy and low complication rate. The number of new cases of pancreatic ductal adenocarcinoma (PDAC) is increasing, and its accurate pathological diagnosis poses a challenge for cytopathologists. Our aim was to develop a hyperspectral imaging (HSI)-based convolution neural network (CNN) algorithm to aid in the diagnosis of pancreatic EUS-FNA cytology specimens...
July 17, 2023: Cancer Medicine
https://read.qxmd.com/read/37373713/real-life-management-of-pancreatic-cysts-simplified-review-of-current-guidelines
#24
REVIEW
Cătălina Vlăduţ, Dana Bilous, Mihai Ciocîrlan
Pancreatic cysts are becoming a popular diagnostic tool due to the increased availability of high-quality cross-sectional imaging. Pancreatic cystic lesions constitute closed, liquid-containing cavities, which are either neoplastic or non-neoplastic. While serous lesions often follow a benign course, mucinous lesions can hide carcinoma and, therefore, require different management. Moreover, all cysts should be considered mucinous until proven otherwise, thus limiting the errors in managing these entities. Due to the need for high contrast soft tissue imaging, magnetic resonance imaging represents an elective, non-invasive diagnostic tool...
June 13, 2023: Journal of Clinical Medicine
https://read.qxmd.com/read/37371782/advances-in-the-early-diagnosis-of-pancreatic-ductal-adenocarcinoma-and-premalignant-pancreatic-lesions
#25
REVIEW
Reiko Yamada, Junya Tsuboi, Yumi Murashima, Takamitsu Tanaka, Kenji Nose, Hayato Nakagawa
Pancreatic cancer is one of the most lethal human malignancies, in part because it is often diagnosed at late stages when surgery and systemic therapies are either unfeasible or ineffective. Therefore, diagnosing pancreatic cancer in earlier stages is important for effective treatment. However, because the signs and symptoms may be nonspecific and not apparent until the disease is at a late stage, the timely diagnoses of pancreatic cancer can be difficult to achieve. Recent studies have shown that selective screening and increased usage of biomarkers could improve the early diagnosis of pancreatic cancer...
June 11, 2023: Biomedicines
https://read.qxmd.com/read/37370909/intraductal-papillary-mucinous-neoplasm-of-the-pancreas-a-challenging-diagnosis
#26
REVIEW
Charikleia Triantopoulou, Sofia Gourtsoyianni, Dimitriοs Karakaxas, Spiros Delis
Intraductal papillary mucinous neoplasm of the pancreas (IPMN) was classified as a distinct entity from mucinous cystic neoplasm by the WHO in 1995. It represents a mucin-producing tumor that originates from the ductal epithelium and can evolve from slight dysplasia to invasive carcinoma. In addition, different aspects of tumor progression may be seen in the same lesion. Three types are recognized, the branch duct variant, the main duct variant, which shows a much higher prevalence for malignancy, and the mixed-type variant, which combines branch and main duct characteristics...
June 9, 2023: Diagnostics
https://read.qxmd.com/read/37270454/clinicopathological-study-of-surgically-treated-non-neoplastic-diseases-of-the-pancreas-with-special-reference-to-autoimmune-pancreatitis
#27
JOURNAL ARTICLE
Makoto Seki, Eiji Ninomiya, Akio Saiura, Yu Takahashi, Yosuke Inoue, Masamichi Katori, Noriko Yamamoto, Manabu Takamatsu, Yo Kato, Keiko Yamada, Kiyoshi Matsueda, Yasuo Ohkura
PURPOSE: After the popularization of serum immunoglobulin G4 (IgG4) measurement and endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) in our institute, surgical resection for non-neoplastic diseases of the pancreas became less common. Although the incidence of such false-positive cases was clarified in the 10-year period after the introduction of these measures (2009-2018), these data were not compared with the 30 years before 2009 (1979-2008). This study was performed to determine the percentage of autoimmune pancreatitis (AIP) that was included during the latter period and how the numbers of false-positive cases differed between the two periods...
June 4, 2023: Langenbeck's Archives of Surgery
https://read.qxmd.com/read/37261505/an-unusual-cytological-presentation-of-solid-pseudopapillary-neoplasm-of-the-pancreas-mimicking-adenoid-cystic-carcinoma-a-case-report-and-literature-review
#28
JOURNAL ARTICLE
Yumiko Higuchi, Eishin Kurihara, Toshihiko Kato, Mei Oshima, Fuki Endo, Fuminori Sato, Tsutomu Kobatake, Masashi Ijima, Shiro Sugihara, Noriyuki Tani, Yosuke Otake, Yasuo Imai
Endoscopic ultrasound-guided fine-needle aspiration has become the common procedure for the diagnosis of pancreatic mass, and cytological examination is usually the first approach. Solid pseudopapillary neoplasm (SPN) cytologically represents papillary structures of branching capillaries surrounded by discohesive neoplastic cells. However, it may present various degrees of tissue degeneration, causing diagnostic challenges. Here, we report a 21-year-old female who had a 2-cm-sized mass in the pancreas head...
June 1, 2023: Virchows Archiv: An International Journal of Pathology
https://read.qxmd.com/read/37189469/metastatic-renal-cell-carcinoma-to-pancreas-case-series-and-review-of-the-literature
#29
Daniel Vasile Balaban, Laura Coman, Flavius Stefan Marin, Marina Balaban, Daniela Tabacelia, Florina Vasilescu, Raluca Simona Costache, Mariana Jinga
Metastasis to the pancreas represents a small proportion of all pancreatic malignancies. Among primary tumors that metastasize to the pancreas, renal cell carcinoma (RCC) is one of the most common causes of metastatic pancreatic lesions. We herein report a case series of three patients with pancreatic metastasis from RCC. The first is a 54-year-old male with a history of left nephrectomy for RCC, in whom an isthmic pancreatic mass suggestive of a neuroendocrine lesion was found during oncological follow-up...
April 7, 2023: Diagnostics
https://read.qxmd.com/read/37174015/comments-on-and-illustrations-of-the-efsumb-ceus-guidelines-transabdominal-and-endoscopic-ultrasound-features-of-intrapancreatic-metastases-and-the-role-of-multiparametric-imaging-and-eus-guided-sampling-in-rare-pancreatic-tumors
#30
REVIEW
Kathleen Möller, Christian Jenssen, Barbara Braden, Michael Hocke, Yasunobu Yamashita, Paolo Giorgio Arcidiacono, André Ignee, Mirko D'Onofrio, Pietro Fusaroli, Manoop S Bhutani, Yi Dong, Siyu Sun, Siegbert Faiss, Christoph F Dietrich
A definite pathologic diagnosis of intrapancreatic metastasis is crucial for the management decision, i.e., curative or palliative surgery versus chemotherapy or conservative/palliative therapy. This review focuses on the appearance of intrapancreatic metastases on native and contrast-enhanced transabdominal ultrasound and endoscopic ultrasound. Differences and similarities in relation to the primary tumor, and the differential diagnosis from pancreatic carcinoma and neuroendocrine neoplasms are described. The frequency of intrapancreatic metastases in autopsy studies and surgical resection studies will be discussed...
April 29, 2023: Cancers
https://read.qxmd.com/read/37171715/challenges-in-managing-upper-gastrointestinal-bleeding-secondary-to-primary-squamous-cell-carcinoma-of-the-pancreas-a-case-report-and-literature-review
#31
JOURNAL ARTICLE
Colin Chan-Min Choi, Yasser Arafat, Maryam Shamassi, Julian Choi
BACKGROUND: Primary pancreatic squamous cell carcinoma (SCC) is a rare type of pancreatic cancer, with an incidence of 5% of all pancreatic cancers. This condition is associated with a poor prognosis, and no optimal treatment has been established (Zhang et al. in Medicine (Baltim). 97:e12253, 2018). CASE PRESENTATION: A 56-year-old man presented to our hospital with upper gastrointestinal bleeding and new-onset diabetes mellitus. He had no other medical comorbidities, episodes of pancreatitis and symptoms secondary to pancreatic insufficiency...
May 12, 2023: Surgical Case Reports
https://read.qxmd.com/read/37164668/pancreatic-metastases-from-renal-cell-carcinoma-showing-atypical-imaging-findings
#32
JOURNAL ARTICLE
Yosuke Ohashi, Keisuke Iwata, Tsuyoshi Mukai, Yuhei Iwasa, Mitsuru Okuno, Akihiko Sugiyama, Youichi Nishigaki, Takuji Tanaka, Eiichi Tomita, Takuji Iwashita, Masahito Shimizu
A 59-year-old man receiving sunitinib chemotherapy for postoperative recurrence of renal cell carcinoma (RCC) metastases was found to have multiple metastases on contrast-enhanced computed tomography (CECT). CECT revealed a typical hyperdense enhanced nodule in the arterial phase of the stomach and head and tail of the pancreas. However, in the uncinate process of the pancreas, CECT revealed an atypical image and a hypodense enhanced nodule in each phase. Both lesions were finally pathologically diagnosed as clear cell carcinoma...
January 1, 2024: Internal Medicine
https://read.qxmd.com/read/37148142/a-rare-case-of-pancreatic-acinar-cell-carcinoma-presenting-a-submucosal-tumor
#33
JOURNAL ARTICLE
Ryo Sugiura, Hidetoshi Kagaya, Hideaki Nakamura, Shoichi Horita, Takashi Meguro, Kiyotaka Sasaki, Tatsuya Yoshida, Hironori Aoki, Masaki Kuwatani, Masayuki Fukushima, Takayuki Morita, Miyoshi Fujita, Keisuke Okamura, Eiji Tamoto, Takashi Ueno, Akio Tsutaho, Ayano Inoue, Toshiyuki Takahashi
No abstract text is available yet for this article.
2023: Endoscopic Ultrasound
https://read.qxmd.com/read/37148140/assessment-of-biological-effect-of-nab-paclitaxel-combined-with-gemcitabine-using-contrast-enhanced-ultrasonography-and-elastography-in-advanced-pancreatic-ductal-carcinoma-a-single-center-pilot-study
#34
JOURNAL ARTICLE
Yanis Dahel, Brice Chanez, Christophe Zemmour, Gilles Piana, Emmanuel Mitry, Marc Giovannini
EUS associated with contrast-enhanced harmonic EUS (CH-EUS) and EUS elastography (EUS-E) are used in clinical practice to assess pancreatic tumor at the diagnosis. In case of pancreatic ductal adenocarcinoma (PDAC) with liver metastasis, nab-paclitaxel combined with gemcitabine is a first-line treatment option. We aimed to assess the modification of PDAC microenvironment induced by the combination of nab-paclitaxel with gemcitabine, by endoscopic ultrasonography techinics. This single center phase III study conducted between February 2015 and June 2016 included patients with pancreatic adenocarcinoma with mesurable liver metastasis and no prior cancer treatment fit for two cycles of nab-paclitaxel combined with gemcitabine...
2023: Endoscopic Ultrasound
https://read.qxmd.com/read/37078931/diagnostic-categories-and-key-features-for-pathological-diagnosis-of-endoscopic-ultrasound-guided-fine-needle-aspiration-biopsy-samples-of-pancreatic-lesions-a-consensus-study
#35
JOURNAL ARTICLE
Yoshiki Naito, Kenji Notohara, Yuko Omori, Shinichi Aishima, Takao Itoi, Nobuyuki Ohike, Yoshinobu Okabe, Motohiro Kojima, Takuma Tajiri, Mariko Tanaka, Masayuki Tsuneki, Toshio Nakagohri, Tomoko Norose, Kenichi Hirabayashi, Yuki Fukumura, Tomoko Mitsuhashi, Hiroshi Yamaguchi, Noriyoshi Fukushima, Toru Furukawa
OBJECTIVES: This study aimed to establish a reliable and reproducible categorized diagnostic classification system with identification of key features to achieve accurate pathological diagnosis of endoscopic ultrasound-guided fine needle aspiration biopsy (EUS-FNAB) samples of pancreatic lesions. METHODS: Twelve pathologists examined virtual whole-slide images of EUS-FNAB samples obtained from 80 patients according to proposed diagnostic categories and key features for diagnosis...
October 1, 2022: Pancreas
https://read.qxmd.com/read/36884386/eus-guided-fine-needle-biopsy-is-able-to-provide-diagnosis-in-rare-osteoclast-like-giant-cells-undifferentiated-carcinoma-of-the-pancreas-report-of-two-cases
#36
JOURNAL ARTICLE
Ruxandra Mihaela Pop, Claudia Irina Diaconu, Mihai Rimbaş, Radu Bogdan Mateescu, Farid Rouhani, Cristiana Popp, Erminia Manfrin, Stefano Francesco Crinò, Victor Cauni
Undifferentiated carcinoma of the pancreas with osteoclast-like giant cells (UC-OGC) is a rare subtype of pancreatic cancer, accounting for less than 1% of all pancreatic tumors. Preoperative diagnosis is cumbersome as cross-sectional imaging is often not capable to distinguish between UCOGC and other pancreatic tumors such as pancreatic adenocarcinoma, mucinous carcinoma or neuroendocrine tumors and specific tumor markers seem to be lacking. Endoscopic ultrasound r `m(EUS) with tissue acquisition via fine-needle aspiration (FNA) or biopsy (FNB) with microscopic HE staining and immunohistochemistry allows for an accurate diagnosis, thus influencing further treatment...
March 8, 2023: Romanian Journal of Internal Medicine
https://read.qxmd.com/read/36861510/role-of-eus-combined-with-a-newly-modified-scoring-system-to-detect-pancreatic-high-grade-precancerous-lesions
#37
JOURNAL ARTICLE
Ryota Sagami, Kenji Hayasaka, Tetsuro Ujihara, Tomoyuki Iwaki, Yasushi Katsuyama, Hideaki Harada, Yusuke Ome, Goro Honda, Shin-Ichiro Horiguchi, Kazunari Murakami, Yuji Amano
BACKGROUNDS AND OBJECTIVES: Although pancreatic cancer (PC) has an extremely poor prognosis, the 5-year survival rate of patients with pancreatic high-grade precancerous lesion without invasive carcinoma (PHP) is favorable. PHP diagnosis and identification of patients requiring intervention are needed. We aimed to validate a modified PC detection scoring system regarding its detection ability for PHP and PC in the general population. SUBJECTS AND METHODS: We modified an existing PC detection scoring system that incorporates low-grade risk (LGR) factors (family history, presence of diabetes mellitus [DM] or worsening DM, heavy drinking, smoking, stomach symptoms, weight loss, and pancreatic enzyme) and high-grade risk (HGR) factors (new-onset DM, familial PC, jaundice, tumor biomarkers, chronic pancreatitis, intraductal papillary mucinous neoplasm, cysts, hereditary PC syndrome, and hereditary pancreatitis)...
2023: Endoscopic Ultrasound
https://read.qxmd.com/read/36694023/granular-cell-tumour-of-the-pancreas-a-case-report-and-systematic-review
#38
JOURNAL ARTICLE
Kevin Tree, Krishna Kotecha, Shreya Mehta, Talia L Fuchs, Christopher W Toon, Anthony J Gill, Jaswinder S Samra, Anubhav Mittal
PURPOSE: Granular cell tumours (GCTs) of the pancreas are mostly benign and exceptionally rare, with no unique identifying radiological features. Following a case discussion of a patient with GCT, a comprehensive review of available literature was conducted to identify the common diagnostic features associated with GCT. METHODS: Following a case report identified in our institution, a systematic review was conducted by two authors in accordance with Preferred Reporting Items for Systematic review and Meta-Analysis protocols (PRISMA) guidelines...
January 25, 2023: Langenbeck's Archives of Surgery
https://read.qxmd.com/read/36631120/-a-case-of-pancreatic-adenosquamous-carcinoma-successfully-treated-by-chemoradiotherapy
#39
JOURNAL ARTICLE
Shigenori Takayanagi, Hajime Hanno, Osami Takeda, Kei Yamamoto, Yoshihiro Nakamura, Tomohiro Minami, Miuki Hisamatsu, Nobuyasu Hirai, Yuu Masuoka, Toshio Dozaiku
Pancreatic adenosquamous carcinoma is a rare primary pancreas malignant tumor with very poor prognosis, for which there is no standard treatment. The case was of a 71-year-old woman who was admitted to the hospital with jaundice. A pancreatic head tumor was found, and pancreatic adenosquamous carcinoma was diagnosed in EUS-FNA. Despite confirmed distant metastasis, a multidisciplinary treatment centered on chemoradiotherapy gave her a 28-month prognosis.
2023: Nihon Shokakibyo Gakkai Zasshi, the Japanese Journal of Gastro-enterology
https://read.qxmd.com/read/36534319/retroperitoneal-liposarcoma-with-pancreatic-metastasis-and-gastric-cancer-a-case-report
#40
JOURNAL ARTICLE
Naoto Abe, Takuto Hikichi, Yuichi Waragai, Yuta Takahashi, Ryoichiro Kobashi, Takumi Yanagita, Hiromi Kumakawa, Kazuo Watanabe, Masao Kobayakawa, Hiromasa Ohira
On computed tomography scanning, a 63-year-old man with vomiting and anorexia was discovered to have a mass in the pancreatic body and a retroperitoneal mass extending to the right lobe of the liver. An esophagogastroduodenoscopy revealed an advanced gastric carcinoma in the middle gastric body, and a biopsy specimen revealed a poorly differentiated adenocarcinoma. The pancreatic and retroperitoneal masses were considered metastatic lesions of gastric cancer, and a biopsy was taken from the pancreatic lesion using endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA)...
December 19, 2022: Clinical Journal of Gastroenterology
keyword
keyword
76168
2
3
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.