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https://www.readbyqxmd.com/read/28895052/the-effects-of-periostin-in-a-rat-model-of-isoproterenol-mediated-cardiotoxicity
#1
Mahmut Sözmen, Alparslan K Devrim, Yonca B Kabak, Tuba Devrim, Mert Sudagidan
Periostin is an extracellular matrix protein from fasciclin family, and it plays an important role in the cell adhesion, migration, and growth of the organism. Periostin prevents apoptosis while stimulating cardiomyocytes. The present study was designed to investigate cardioprotective effects of the recombinant murine periostin peptide administration in a rat model of isoproterenol (ISO)-induced myocardial injury. The experiment was performed on 84 adult male Sprague Dawley rats in 4 groups (n = 21): control group (1), periostin-treated group (2), ISO-treated group (3), and ISO + periostin-treated group (4)...
September 11, 2017: Cardiovascular Toxicology
https://www.readbyqxmd.com/read/28891358/defensive-medicine-among-obstetricians-and-gynaecologists-in-turkey
#2
Mert Küçük
In recent years, there has been a remarkable increase in medical malpractice litigations against OB/GYNs in Turkey and globally. This high litigation atmosphere may have changed attitudes, behaviour and practice of OB/GYNs. In the current study, opinions and attitudes of OB/GYNs regarding defensive medicine and to what extent they practice it were investigated. One hundred and eight OB/GYNs participated in the study. All participants found obstetrics and gynaecology riskier when compared with other medical branches and reported that they were increasingly practising defensive medicine...
September 11, 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28889354/predictive-value-of-syntax-score-ii-for-clinical-outcomes-in-cardiogenic-shock-underwent-primary-percutaneous-coronary-intervention-a-pilot-study
#3
Mert İlker Hayıroğlu, Muhammed Keskin, Ahmet Okan Uzun, Emrah Bozbeyoğlu, Özlem Yıldırımtürk, Ömer Kozan, Seçkin Pehlivanoğlu
SYNTAX Score II (SSII) connects clinical variables with coronary anatomy. We investigated the prognostic value of SSII in patients with ST segment elevated myocardial infarction (STEMI) complicated with cardiogenic shock treated with primary percutaneous coronary intervention (PPCI). In this retrospective analysis, we evaluated the in-hospital prognostic impact of SSII on 492 patients with STEMI complicated with cardiogenic shock treated with PPCI. Patients were stratified by tertiles of SSII, in-hospital clinical outcomes were compared between those groups...
September 9, 2017: International Journal of Cardiovascular Imaging
https://www.readbyqxmd.com/read/28883308/successful-management-of-iatrogenic-retrograde-dissection-into-the-aortic-root
#4
Kadir Uğur Mert, Gurbet Özge Mert, Rafet Dizman
No abstract text is available yet for this article.
September 2017: Anatolian Journal of Cardiology
https://www.readbyqxmd.com/read/28880530/novel-in-situ-techniques-for-studies-of-model-catalysts
#5
Edvin Lundgren, Chu Zhang, Lindsay R Merte, Mikhail Shipilin, Sara Blomberg, Uta Hejral, Jianfeng Zhou, Johan Zetterberg, Johan Gustafson
Motivated mainly by catalysis, gas-surface interaction between single crystal surfaces and molecules has been studied for decades. Most of these studies have been performed in well-controlled environments and have been instrumental for the present day understanding of catalysis, providing information on surface structures, adsorption sites, and adsorption and desorption energies relevant for catalysis. However, the approach has been criticized for being too far from a catalyst operating under industrial conditions at high temperatures and pressures...
September 7, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/28868164/who-needs-high-fio2
#6
Ozan Akca, Lorenzo Ball, F Javier Belda, Peter Biro, Andrea Cortegiani, Arieh Eden, Carlos Ferrando, Luciano Gattinoni, Zeev Goldik, Cesare Gregoretti, Thomas Hachenberg, Göran Hedenstierna, Harriet W Hopf, Thomas K Hunt, Paolo Pelosi, Motaz Qadan, Daniel I Sessler, Marina Soro, Mert Şentürk
World Health Organization and the United States Center for Disease Control have recently recommended the use of 0.8 FIO2 in all adult surgical patients undergoing general anaesthesia, to prevent surgical site infections. This recommendation has arisen several discussions: As a matter of fact, there are numerous studies with different results about the effect of FIO2 on surgical site infection. Moreover, the clinical effects of FIO2 are not limited to infection control. We asked some prominent authors about their comments regarding the recent recommendations...
August 2017: Turkish Journal of Anaesthesiology and Reanimation
https://www.readbyqxmd.com/read/28867124/effect-of-nonalcoholic-fatty-liver-disease-on-in-hospital-and-long-term-outcomes-in-patients-with-st-segment-elevation-myocardial-infarction
#7
Muhammed Keskin, Mert İlker Hayıroğlu, Ahmet Okan Uzun, Tolga Sinan Güvenç, Sinan Şahin, Ömer Kozan
Nonalcoholic fatty liver disease (NAFLD) is a risk factor for coronary artery disease. We investigated the effect of NAFLD grade on in-hospital and long-term outcomes in patients with ST-segment elevation myocardial infarction (STEMI). The study group consisted of 360 patients with STEMI. The patients were classified according to the grade of the NAFLD using ultrasonography. Based on this classification, all patients were divided into 4 subgroups as grade 0 (no fatty liver disease), grade 1, grade 2, and grade 3...
August 8, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28866335/predictors-of-outcomes-and-refractoriness-in-status-epilepticus-a-prospective-study
#8
Murat Mert Atmaca, Nerses Bebek, Betül Baykan, Ayşen Gökyiğit, Candan Gürses
OBJECTIVE: The objective of this study was to determine the predictors of outcomes and refractoriness in status epilepticus (SE). METHODS: This is a prospective study of 59 adult patients with SE who were admitted to the Emergency Department between February 2012 and December 2013. The effects of clinical, demographic, and electrophysiologic features of patients with SE were evaluated. To evaluate outcome in SE, STESS, mSTESS, and EMSE scales were used. RESULTS: Logistic regression analysis showed that being aged ≥65years (p=0...
August 31, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28864336/analysis-of-transfusion-related-acute-lung-injury-and-possible-transfusion-related-acute-lung-injury-reported-to-the-french-hemovigilance-network-from-2007-to-2013
#9
REVIEW
Georges Andreu, Karim Boudjedir, Jean-Yves Muller, Elodie Pouchol, Yves Ozier, Guillaume Fevre, Chantal Gautreau, Jean-François Quaranta, Christian Drouet, Claire Rieux, Paul-Michel Mertes, Benoit Clavier, Monique Carlier, Imad Sandid
Using the French Hemovigilance Network database from 2007 to 2013, we provide information on demographics, incidence, and risk factors of reported transfusion-related acute lung injury (TRALI) and possible TRALI, analyze TRALI mitigation efforts for fresh frozen plasma and platelet concentrates, and consider the impact of platelet additive solutions on TRALI incidence. We applied the Toronto consensus conference definitions for TRALI and possible TRALI. Two TRALI subgroups were considered: "antibody positive" when a donor has human leukocyte antigen (class I or II) and/or human neutrophil antigen antibodies and the recipient has cognate antigen, and "antibody negative" when immunological investigation is negative or not done...
July 15, 2017: Transfusion Medicine Reviews
https://www.readbyqxmd.com/read/28864320/effect-of-adjunctive-thrombus-aspiration-on-in-hospital-and-3-year-outcomes-in-patients-with-st-segment-elevation-myocardial-infarction-and-large-native-coronary-artery-thrombus-burden
#10
Muhammed Keskin, Adnan Kaya, Mustafa Adem Tatlısu, Osman Uzman, Edibe Betül Börklü, Göksel Çinier, Ahmet İlker Tekkeşin, Ceyhan Türkkan, Mert İlker Hayıroğlu, Ömer Kozan
Although the long-term clinical benefit of adjunctive thrombus aspiration (TA) during primary percutaneous coronary intervention (PPCI) remains controversial, the impact of TA in patients with large thrombus has not been evaluated. The aim of the present study was to investigate the effect of adjunctive TA during PPCI on clinical outcomes in patients with ST-segment elevation myocardial infarction (STEMI) and a large thrombus. We assessed the effect of adjunctive TA on in-hospital and 3-year clinical outcomes in 627 patients with STEMI and a large thrombus in the native coronary artery...
August 4, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28863515/novel-tilt-curvature-coupling-in-lipid-membranes
#11
M Mert Terzi, Markus Deserno
On mesoscopic scales, lipid membranes are well described by continuum theories whose main ingredients are the curvature of a membrane's reference surface and the tilt of its lipid constituents. In particular, Hamm and Kozlov [Eur. Phys. J. E 3, 323 (2000)] have shown how to systematically derive such a tilt-curvature Hamiltonian based on the elementary assumption of a thin fluid elastic sheet experiencing internal lateral pre-stress. Performing a dimensional reduction, they not only derive the basic form of the effective surface Hamiltonian but also express its emergent elastic couplings as trans-membrane moments of lower-level material parameters...
August 28, 2017: Journal of Chemical Physics
https://www.readbyqxmd.com/read/28844168/effects-of-heart-rate-reduction-with-ivabradine-on-the-international-%C3%A4-ndex-of-erectile-function-iief-5-in-patients-with-heart-failure
#12
Kadir Uğur Mert, Muhammet Dural, Gurbet Özge Mert, Kemal Iskenderov, Ata Özen
INTRODUCTION: The presence of concomitant erectile dysfunction (ED) with heart failure (HF) is not surprising, because endothelial dysfunction is pathophysiologic signature of both ED and HF. ED significantly and adversely affects quality of life in patients with HF. It was demonstrated that ivabradine treatment can improve endothelial function and ED in experimental models. In this study, we aimed to determine the effect of ivabradine treatment on ED in patients with HF via International Index of Erectile Function (IIEF-5) questionaire...
August 26, 2017: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/28842967/zeolite-loaded-alginate-chitosan-hydrogel-beads-as-a-topical-hemostat
#13
Parinaz Fathi, Michael Sikorski, Katerina Christodoulides, Kristen Langan, Yoon Sun Choi, Michael Titcomb, Anjali Ghodasara, Omasiri Wonodi, Hemi Thaker, Mert Vural, Adam Behrens, Peter Kofinas
Hemorrhage is the leading cause of preventable death after a traumatic injury, and the largest contributor to loss of productive years of life. Hemostatic agents accelerate hemostasis and help control hemorrhage by concentrating coagulation factors, acting as procoagulants and/or interacting with erythrocytes and platelets. Hydrogel composites offer a platform for targeting both mechanical and biological hemostatic mechanisms. The goal of this work was to develop hydrogel particles composed of chitosan, alginate, and zeolite, and to assess their potential to promote blood coagulation via multiple mechanisms: erythrocyte adhesion, factor concentration, and the ability to serve as a mechanical barrier to blood loss...
August 26, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28842084/endoscopic-plantar-fasciotomy-deep-fascial-versus-superficial-fascial-approach-a-prospective-randomized-study
#14
Bilgehan Çatal, Mert Keskinbora, Mehmet Ali Uysal, Mustafa Şahin, Deniz Gulabi, Bahtiyar Demiralp
In the present randomized prospective study, 2 different surgical techniques of endoscopic plantar fascia release were compared. Of 547 patients with a diagnosis of plantar fasciitis, 46 with no response to conservative treatment for ≥6 months were included. Of the 46 patients, 5 were lost to follow-up. In group 1 (n = 21), plantar fascia release was performed using a deep fascial approach (DFA), and in group 2 (n = 20), the superficial fascial approach (SFA) with a slotted cannula technique was used...
September 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28821788/bioenergetic-adaptations-in-chemoresistant-ovarian-cancer-cells
#15
Sajad Dar, Jasdeep Chhina, Ismail Mert, Dhananjay Chitale, Thomas Buekers, Hareena Kaur, Shailendra Giri, Adnan Munkarah, Ramandeep Rattan
Earlier investigations have revealed that tumor cells undergo metabolic reprogramming and mainly derive their cellular energy from aerobic glycolysis rather than oxidative phosphorylation even in the presence of oxygen. However, recent studies have shown that certain cancer cells display increased oxidative phosphorylation or high metabolically active phenotype. Cellular bioenergetic profiling of 13 established and 12 patient derived ovarian cancer cell lines revealed significant bioenergetics diversity. The bioenergetics phenotype of ovarian cancer cell lines correlated with functional phenotypes of doubling time and oxidative stress...
August 18, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28815340/intradural-lumbosacral-malignant-extrarenal-rhabdoid-tumor-a-case-report
#16
Richard Justin Garling, Rasanjeet Singh, Carolyn Harris, Abilash Haridas
BACKGROUND: Rhabdoid tumors are highly malignant tumors predominantly affecting the pediatric population. When these tumors occur outside of the kidneys, they are referred to as malignant extrarenal rhabdoid tumors (MERT), a rare highly aggressive subtype. Less commonly, these tumors involve the neuro-axis. OBJECTIVE: Here we present a case of a 15-year-old girl with intradural MERT of the lumbosacral spine who presented with back pain, sudden worsening of lower extremity strength, and complete loss of bowel and bladder control...
August 16, 2017: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
https://www.readbyqxmd.com/read/28807756/first-time-identification-of-acanthamoeba-genotypes-in-the-cornea-samples-of-wild-birds-is-acanthamoeba-keratitis-making-the-predatory-birds-a-target
#17
Muhammet Karakavuk, Mehmet Aykur, Esra Atalay Şahar, Mehmet Karakuş, Duygu Aldemir, Ömer Döndüren, Hüseyin Gökhan Özdemir, Hüseyin Can, Adnan Yüksel Gürüz, Hande Dağcı, Mert Döşkaya
Acanthamoeba is a free-living amoeba which can be isolated from environment and among others well known as an opportunist protozoan parasite causing infections in humans and animals. Eyes are extremely important for the wild birds and losing sight ability due to Acanthamoeba can be dangerous. The studies on Acanthamoeba infection in wild birds is very few in world and Turkey therefore we aimed to screen deceased wild birds found in İzmir and Manisa provinces located in western Turkey using PCR and non-nutrition agar (NNA) plate method...
August 12, 2017: Experimental Parasitology
https://www.readbyqxmd.com/read/28768230/thermal-stress-analysis-of-ceramic-laminate-veneer-restorations-with-different-incisal-preparations-using-micro-computed-tomography-based-3d-finite-element-models
#18
Alper Tunga Celebi, Esra Icer, Meltem Mert Eren, Cengiz Baykasoglu, Ata Mugan, Esra Yildiz
Main objective of this study is to investigate the thermal behavior of ceramic laminate veneer restorations of the maxillary central incisor with different incisal preparations such as butt joint and palatinal chamfer using finite element method. In addition, it is also aimed to understand the effect of different thermal loads which simulates hot and cold liquid imbibing in the mouth. Three-dimensional solid models of the sound tooth and prepared veneer restorations were obtained using micro-computed tomography images...
July 27, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28766365/concomitant-use-of-transvaginal-sonography-and-doppler-indices-improve-diagnosis-of-adenomyosis
#19
Duygu Kara Bozkurt, Murat Bozkurt, Ahmet Said Cil, Mert Ulaş Barut, Aynur Adeviye Ersahin, Eray Çalıskan
This study was planned to investigate whether measuring of Doppler indices with TV-DUS improved the diagnosis of adenomyosis. Preoperative Doppler indices of subjects with a preliminary diagnosis of adenomyosis were compared with the histopathological results of excised specimens. Sensitivity, specificity and positive/negative predictive values (PPV, NPV) of the measured indices were also calculated. Sensitivity, specificity, PPV and NPV and positive and negative likelihood ratios (LR+) and (LR-) of TV-US in the diagnosis of adenomyosis were found to be 70...
October 2017: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/28765767/simple-and-effective-solution-for-diaphragm-pacing-by-that-uses-the-transvenous-femoral-approach-in-a-patient-treated-with-cardiac-resynchronization-defibrillator-therapy-the-wrapping-method
#20
Ahmet Taha Alper, Mert İlker Hayıroğlu, Ahmet İlker Tekkeşin, Ceyhan Türkkan
The use of cardiac resynchronization therapy (CRT) has become widespread in patients with heart failure who meet the criteria for implantation. Coronary sinus lead positioning is important to provide the intended biventricular stimulation. Diaphragm pacing is a lead-related complication which occurs secondary to phrenic nerve stimulation. We present the case of a 58-year-old male patient who had diaphragm pacing after CRT with defibrillator implantation. The complication was resolved by using the transvenous femoral approach with the wrapping method...
August 2017: Journal of Arrhythmia
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