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https://www.readbyqxmd.com/read/28443588/solitary-fibrous-tumors-of-chest-another-look-with-the-oncologic-perspective
#1
Mert Saynak, Nirmal K Veeramachaneni, Jessica L Hubbs, Dilruba Okumuş, Lawrence B Marks
B Solitary fibrous tumors (SFT) are mesenchymal lesions that arise at a variety of sites, most commonly the pleura. Most patients are asymptomatic at diagnosis, with lesions being detected incidentally. Nevertheless, some patients present due to symptoms from local tumor compression (eg. of the airways and pulmonary parenchyma). Furthermore, radiological methods are not always conclusive in making a diagnosis, and thus, pathological analysis is often required. In the past three decades, immunohistochemical techniques have provided a gold standard in SFT diagnosis...
April 6, 2017: Balkan Medical Journal
https://www.readbyqxmd.com/read/28442552/the-role-of-anticipated-decision-regret-and-the-patient-s-best-interest-in-sterilisation-and-medically-assisted-reproduction
#2
Heidi Mertes
There is a clear discrepancy in the way those who request medical assistance in pursuit of their reproductive choices are treated. On the one hand, women who request a sterilisation are urged to consider possible future regrets and are sometimes refused treatment in anticipation of such regrets. This is despite the fact that for all age ranges, the majority of women undergoing a sterilisation do not regret the decision. Moreover, women who are voluntarily childless are likely to have a happier and more gratifying life than parents...
May 2017: Journal of Medical Ethics
https://www.readbyqxmd.com/read/28436092/effects-of-creatine-supplementation-on-cardiac-autonomic-functions-in-bodybuilders
#3
Kadir Uğur Mert, Serdar Ilgüy, Muhammet Dural, Gurbet Özge Mert, Engin Özakin
Bodybuilder-type workouts may affect heart rate variability (HRV), which has considerable potential to assess the role of autonomic nervous system (ANS). A scientifically designed approach is necessary for bodybuilders to achieve better results while protecting their health. In this study, we aimed to investigate HRV parameters in bodybuilders compared to healthy control subjects and effects of creatine supplementation. Total 48 male participants (16 controls, 16 supplement(-), 16 supplement(+) were evaluated in our study...
April 24, 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/28430676/a-biomimetic-alternative-to-synthetic-hydroxyapatite-boron-containing-bone-like-hydroxyapatite-precipitated-from-simulated-body-fluid
#4
Mert Calis, Tugrul Tolga Demirtas, Alper Vatansever, Gulseren Irmak, Ahmet Hamdi Sakarya, Pergin Atilla, Figen Ozgur, Menemse Gumusderelioglu
BACKGROUND: Biological hydroxyapatite (HA), has several mechanical and physical advantages over the commercially available synthetic apatite (CAP-HA). The aim of this in vivo study was to investigate the effect of osteoinductive "bone-like hydroxyapatite" obtained from simulated body fluid (SBF) combined with osteoinductive "boron" (B) on bone healing. MATERIALS: Bone like nanohydroxyapatite (SBF-HA) was precipitated from 10× simulated body fluid (10×SBF). Thirty Sprague-Dawley rats were randomly divided into 5 experimental groups (n = 6 each)...
April 20, 2017: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/28425458/anatomy-of-terminal-moraine-segments-and-implied-lake-stability-on-ngozumpa-glacier-nepal-from-electrical-resistivity-tomography-ert
#5
Sarah S Thompson, Bernd Kulessa, Douglas I Benn, Jordan R Mertes
Moraine-dammed lakes at debris-covered glaciers are becoming increasingly common and pose significant outburst flood hazards if the dam is breached. While moraine subsurface structure and internal processes are likely to influence dam stability, only few sites have so far been investigated. We conducted electrical resistivity tomography (ERT) surveys at two sites on the terminal moraine complex of the Ngozumpa Glacier, Nepal, to aid assessment of future terminus stability. The resistivity signature of glacier ice at the site (100-15 kΩ m) is more consistent with values measured from cold glacier ice and while this may be feasible, uncertainties in the data inversion introduce ambiguity to this thermal interpretation...
April 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28424447/case-images-detection-and-management-of-icd-lead-implanted-in-middle-cardiac-vein
#6
Ahmet Taha Alper, Ahmet İlker Tekkeşin, Mert İlker Hayıroğlu, Yasin Çakıllı, Göksel Çinier
No abstract text is available yet for this article.
March 2017: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/28416978/atrial-electromechanical-delay-in-patients-undergoing-heart-transplantation
#7
Mustafa Bulut, Mert Evlice, Mehmet Celik, Hayati Eren, Ömer F Savluk, Rezzan D Acar, Mustafa Tabakci, Mehmet Y Emiroglu, Ozlem Otcu Nurse, Ramazan Kargin, Mehmet Balkanay, Mustafa Akcakoyun
BACKGROUND: We aimed to assess atrial electromechanical delay (AEMD) in patients who had undergone heart transplantation. METHODS: A total of 32 patients who underwent biatrial anastomosis heart transplantation (24 men, 8 women; mean age: 42±11 years) and 30 healthy volunteers (20 men, 10 women; mean age: 36±13 years) were included in the study. Atrial electromechanical coupling (PA), intra-AEMD, and inter-AEMD were measured. RESULTS: PA lateral (68±7 vs...
April 2017: Journal of Arrhythmia
https://www.readbyqxmd.com/read/28416930/what-are-the-prevalence-of-abdominal-aortic-aneurysm-in-patients-with-chronic-obstructive-pulmonary-diseases-and-the-characteristics-of-these-patients
#8
Ulku Aka Akturk, Nagihan Durmus Kocak, Suleyman Akturk, Mert Dumantepe, Aysun Sengul, Mehmet Arif Akcay, Makbule Ozlem Akbay, Feyyaz Kabadayi, Dilek Ernam
OBJECTIVE: To determine the prevalence of abdominal aortic aneurysm (AAA) in patients with chronic obstructive pulmonary disease (COPD) and to assess the characteristics of these patients. MATERIALS AND METHODS: Stable COPD patients (age, >40 years) were included in the study between January 2014 and June 2014. Patients with acute exacerbations and a previous lung resection were excluded. Data regarding demographic characteristics were recorded. The modified Medical Research Council (mMRC) dyspnea scale was used to assess the severity of breathlessness...
February 2017: Eurasian Journal of Medicine
https://www.readbyqxmd.com/read/28416924/comparison-of-second-and-third-generation-nails-in-the-treatment-of-intertrochanteric-fracture-screws-versus-helical-blades
#9
Mert Kumbaraci, Levent Karapinar, Ali Turgut
OBJECTIVE: The aim of this study was to compare the radiological and functional outcomes of anti-rotation trochanteric nails (ATNs) with proximal femoral nail anti-rotation (PFNA) in the treatment of intertrochanteric femur fractures in elderly patients. MATERIALS AND METHODS: In total, 165 intertrochanteric fractures were treated between January 2007 and January 2010. One hundred forty patients were included. The operation time, amount of blood loss, fluoroscopy screening time, and length of hospitalization were recorded...
February 2017: Eurasian Journal of Medicine
https://www.readbyqxmd.com/read/28416451/diffeomorphic-functional-brain-surface-alignment-functional-demons
#10
Karl-Heinz Nenning, Hesheng Liu, Satrajit Ghosh, Mert Sabuncu, Ernst Schwartz, Georg Langs
Aligning brain structures across individuals is a central prerequisite for comparative neuroimaging studies. Typically, registration approaches assume a strong association between the features used for alignment, such as macro-anatomy, and the variable observed, such as functional activation or connectivity. Here, we propose to use the structure of intrinsic resting state fMRI signal correlation patterns as a basis for alignment of the cortex in functional studies. Rather than assuming the spatial correspondence of functional structures between subjects, we have identified locations with similar connectivity profiles across subjects...
April 14, 2017: NeuroImage
https://www.readbyqxmd.com/read/28415643/new-transcriptional-based-insights-into-the-pathogenesis-of-desmoplastic-small-round-cell-tumors-dsrcts
#11
Tiziana Negri, Silvia Brich, Fabio Bozzi, Chiara V Volpi, Ambra V Gualeni, Silvia Stacchiotti, Loris De Cecco, Silvana Canevari, Annunziata Gloghini, Silvana Pilotti
To gain new insights into desmoplastic small round cell tumors (DSRCTs) by means of gene expression profiling (GEP). Formalin-fixed, paraffin-embedded surgical specimens obtained from seven pretreated DSRCT patients were interrogated using GEP complemented by immunohistochemistry, a cancer stem cell array, and miRNA in situ hybridisation, including the combined chimera modules miRNA-200/ZEB1 and miRNA-34/SLUG. The chimera modules divided the cases into three classes that respectively recapitulated the traits of mesenchymal epithelial reverse transition (MErT), epithelial mesenchymal transition (EMT), and hybrid/partial EMT...
March 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/28414063/hypersensitivity-transfusion-reactions-due-to-iga-deficiency-are-rare-according-to-french-hemovigilance-data
#12
Charles Tacquard, Karim Boudjedir, Monique Carlier, Jean-Yves Muller, Philippe Gomis, Paul Michel Mertes
In an analysis of a large French hemovigilance database (2004-2014), hypersensitivity transfusion reactions (HTRs) due to IgA deficiency were extremely rare with an frequency far lower than reported so far. In depth investigation of HTRs for IgA deficiency should be limited to moderate to severe recurrent reactions.
April 13, 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28407216/real-world-stroke-prevention-strategies-in-nonvalvular-atrial-fibrillation-in-patients-with-renal-impairment
#13
Kadir Uğur Mert, Gurbet Özge Mert, Özcan Başaran, Osman Beton, Volkan Dogan, Mehmet Tekinalp, Ahmet Çağrı Aykan, Ezgi Kalaycıoğlu, Ismail Bolat, Onur Taşar, Özgen Şafak, Macit Kalçık, Mehmet Yaman, Cevat Kırma, Murat Biteker
BACKGROUND: The data regarding stroke prevention strategies in non-valvular atrial fibrillation (NVAF) is limited especially in patients with renal impairment (RI). We sought to evaluate management dilemmas in patients with concurrent NVAF and RI in RAMSES (ReAl-life Multicenter Survey Evaluating Stroke Prevention Strategies inTurkey) study. METHODS: We conducted a prospective, multicenter, nation-wide registry in NVAF patients in outpatient cardiology clinics. All consecutive patients with nonvalvular atrial fibrillation were enrolled in RAMSES Study (ClinicalTrials...
April 13, 2017: European Journal of Clinical Investigation
https://www.readbyqxmd.com/read/28405925/a-survey-of-metal-concentrations-in-marine-sediment-cores-in-the-vicinity-of-an-old-mercury-mining-area-in-karaburun-aegean-sea
#14
Ebru Yesim Ozkan, Hasan Baha Buyukisik, Aynur Kontas, Mert Turkdogan
The aim of this study was to assess the historical trends of metal concentrations in coastal sediments in the vicinity of an inactive mining area, find background values and contamination levels of metals around the Karaburun peninsula, and then search for other sources of mercury in marine sediment cores using multivariate statistical analysis and report the potential ecological risks from that metal contamination. Surface sediment samples were taken from seven stations. Water depths were less than 20 m (coastal area) at stations KB07 and KB08...
April 12, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28401800/a-novel-independent-survival-predictor-in-pulmonary-embolism-prognostic-nutritional-index
#15
Mert İlker Hayıroğlu, Muhammed Keskin, Taha Keskin, Ahmet Okan Uzun, Servet Altay, Adnan Kaya, Ahmet Öz, Göksel Çinier, Tolga Sinan Güvenç, Ömer Kozan
The prognostic impact of nutritional status in patients with pulmonary embolism (PE) is poorly understood. A well-accepted nutritional status parameter, prognostic nutritional index (PNI), which was first demonstrated to be valuable in patients with cancer and gastrointestinal surgery, was introduced to patients with PE. Our aim was to evaluate the predictive value of PNI in outcomes of patients with PE. We evaluated the in-hospital and long-term (53.8 ± 5.4 months) prognostic impact of PNI on 251 patients with PE...
January 1, 2017: Clinical and Applied Thrombosis/hemostasis
https://www.readbyqxmd.com/read/28390224/maternal-anxiety-related-to-prenatal-diagnoses-of-fetal-anomalies-that-require-surgery
#16
Abigail B Wilpers, Holly Powell Kennedy, Diane Wall, Marjorie Funk, Mert Ozan Bahtiyar
OBJECTIVES: To investigate maternal anxiety in women with pregnancies complicated by fetal anomalies that require surgery. DESIGN: Prospective comparison pilot study. SETTING: A fetal care center in a Northeastern U.S. academic medical center. PARTICIPANTS: Women in their second or early third trimesters of pregnancy; 19 with pregnancies complicated by fetal anomalies and 25 without. METHODS: After ultrasonography, all participants completed the Spielberger State-Trait Anxiety Inventory and a sociodemographic questionnaire...
April 5, 2017: Journal of Obstetric, Gynecologic, and Neonatal Nursing: JOGNN
https://www.readbyqxmd.com/read/28388634/phenome-wide-heritability-analysis-of-the-uk-biobank
#17
Tian Ge, Chia-Yen Chen, Benjamin M Neale, Mert R Sabuncu, Jordan W Smoller
Heritability estimation provides important information about the relative contribution of genetic and environmental factors to phenotypic variation, and provides an upper bound for the utility of genetic risk prediction models. Recent technological and statistical advances have enabled the estimation of additive heritability attributable to common genetic variants (SNP heritability) across a broad phenotypic spectrum. Here, we present a computationally and memory efficient heritability estimation method that can handle large sample sizes, and report the SNP heritability for 551 complex traits derived from the interim data release (152,736 subjects) of the large-scale, population-based UK Biobank, comprising both quantitative phenotypes and disease codes...
April 2017: PLoS Genetics
https://www.readbyqxmd.com/read/28387945/obstetrician-perceptions-of-the-causes-of-high-cesarean-delivery-rates-in-turkey
#18
Mert Küçük
OBJECTIVE: To assess obstetricians' perceptions surrounding cesarean delivery rates in Turkey. METHODS: The present cross-sectional descriptive study was performed between May 1 and June 30, 2016. Practicing obstetricians with contact details known by the researchers and those attending a conference in Turkey were asked to complete a self-administered questionnaire that collected demographic data and information on participants' opinions, beliefs, knowledge, attitudes, and practices related to cesarean delivery...
April 7, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28381372/investigation-of-the-speech-results-of-posterior-pharyngeal-wall-augmentation-with-fat-grafting-for-treatment-of-velopharyngeal-insufficiency
#19
Çağla Dinsever Eliküçük, Maviş Emel Kulak Kayıkcı, Fatma Esen Aydınlı, Mert Çalış, Fatma Figen Özgür, Mehtap Öztürk, Rıza Önder Günaydın
PURPOSE: The purpose of this study was to evaluate the speech results of posterior pharyngeal wall augmentation (PPWA) with fat grafting both in the early and late postoperative period, and to clarify the impact of the procedure concomitant with speech therapy. MATERIALS AND METHODS: This is a prospective case-control study. The study involved 87 cleft palate ± cleft lip patients with velopharyngeal insufficiency (VPI) who has been treated with PPWA. Patients were separated into two groups according to age; the first group consisted of 49 pediatric participants between 6 and 12 years of age and the second group consisted of 38 adolescent participants between 13 and 18 years of age...
March 6, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28369036/chromatin-remodeling-factor-smarcd2-regulates-transcriptional-networks-controlling-differentiation-of-neutrophil-granulocytes
#20
Maximilian Witzel, Daniel Petersheim, Yanxin Fan, Ehsan Bahrami, Tomas Racek, Meino Rohlfs, Jacek Puchałka, Christian Mertes, Julien Gagneur, Christoph Ziegenhain, Wolfgang Enard, Asbjørg Stray-Pedersen, Peter D Arkwright, Miguel R Abboud, Vahid Pazhakh, Graham J Lieschke, Peter M Krawitz, Maik Dahlhoff, Marlon R Schneider, Eckhard Wolf, Hans-Peter Horny, Heinrich Schmidt, Alejandro A Schäffer, Christoph Klein
We identify SMARCD2 (SWI/SNF-related, matrix-associated, actin-dependent regulator of chromatin, subfamily D, member 2), also known as BAF60b (BRG1/Brahma-associated factor 60b), as a critical regulator of myeloid differentiation in humans, mice, and zebrafish. Studying patients from three unrelated pedigrees characterized by neutropenia, specific granule deficiency, myelodysplasia with excess of blast cells, and various developmental aberrations, we identified three homozygous loss-of-function mutations in SMARCD2...
April 3, 2017: Nature Genetics
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