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Mizuka Kamoi, Yukihiko Mashima, Motoko Kawashima, Kazuo Tsubota
PURPOSE: To report the efficacy of electrolysis as a treatment of corneal opacities in a young patient with the superficial variant of granular corneal dystrophy. DESIGN: Interventional case report. METHODS: An 11-year-old boy presented with subepithelial opacities in both eyes. His visual acuity was 0.2 in the left eye; he received corneal electrolysis under topical anesthesia. RESULTS: The electrolysis, which required only 5 minutes, resulted in the disappearance of the subepithelial opacities...
June 2005: American Journal of Ophthalmology
M Konishi, M Yamada, Y Nakamura, Y Mashima
PURPOSE: To investigate corneal deposits associated with kerato-epithelin (KE) in three corneal dystrophies harboring mutations at Arg-124 in the BIGH3 gene. METHODS: Six patients with Avellino corneal dystrophy (ACD) associated with R124H, one patient with superficial granular corneal dystrophy (SGCD) associated with R124L, and seven patients with lattice corneal dystrophy type 1 (CDL1) associated with R124C were examined. Corneal buttons obtained during keratoplasties were stained with Masson's trichrome and with Congo red, and immunostained with antibodies specific for N-terminal and C-terminal portions of KE (KE-15 and KE-2, respectively)...
November 2000: Current Eye Research
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