Read by QxMD icon Read

esc 2015

Eiichiro Yamamoto, Yoshihiro Hirata, Takanori Tokitsu, Hiroaki Kusaka, Noriaki Tabata, Kenichi Tsujita, Megumi Yamamuro, Koichi Kaikita, Hiroshi Watanabe, Seiji Hokimoto, Toru Maruyama, Hisao Ogawa
AIMS: Although inflammation plays an important role in the pathogenesis of heart failure (HF), the precise pathophysiological role of inflammation in HF with preserved left ventricular ejection fraction (HFpEF) still remains unclear. Hence, we examined the clinical significance of plasma neopterin, an inflammatory biomarker, in HFpEF patients. METHODS AND RESULTS: In the present study, we recruited consecutive HFpEF patients hospitalized in Kumamoto University Hospital, and further measured plasma neopterin by high-performance liquid chromatography and serum derivatives of reactive oxidative metabolites (DROM), a new biomarker of reactive oxygen species...
March 2016: ESC Heart Failure
Naoko Irie, M Azim Surani
We recently reported a robust and defined culture system for the specification of human primordial germ cell-like cells (hPGCLCs) from human pluripotent stem cells (hPSCs), both embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) in vitro (Irie et al. Cell 160: 253-268, 2015). Similar attempts previously produced hPGCLCs from hPSCs at a very low efficiency, and the resulting cells were not fully characterized. A key step, which facilitated efficient hPGCLC specification from hPSCs, was the induction of a "competent" state for PGC fate via the medium containing a cocktail of four inhibitors...
2017: Methods in Molecular Biology
Sven Reek, Haran Burri, Paul R Roberts, Christian Perings, Andrew E Epstein, Helmut U Klein
The wearable cardioverter-defibrillator has been available for over a decade and now is frequently prescribed for patients deemed at high arrhythmic risk in whom the underlying pathology is potentially reversible or who are awaiting an implantable cardioverter-defibrillator. The use of the wearable cardioverter-defibrillator is included in the new 2015 ESC guidelines for the management of ventricular arrhythmias and prevention of sudden cardiac death. The present review provides insight into the current technology and an overview of this approach...
October 4, 2016: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
Joachim Seichter, Bernhard Schieffer
In 2015, an updated version of the ESC guidelines on pericardial diseases was published. The new guidelines summarize findings in the area of etiology, diagnosis and therapy of pericardial diseases and introduce an algorithm to diagnose pericarditis. Additionally, criteria for hospital submission were introduced. The use of multimodal imaging procedures was emphasized and medical as well as interventional therapy strategies were adapted to current knowledge.
September 2016: Deutsche Medizinische Wochenschrift
Li Liang, Guofeng Ma, Kai Chen, Yangxiang Liu, Xiaohong Wu, Kejing Ying, Ruifeng Zhang
BACKGROUND: Pulmonary veno-occlusive disease (PVOD) is a rare and devastating cause of pulmonary arterial hypertension with a non-specific clinical presentation and a relatively specific presentation in high-resolution thoracic CT scan images. Definitive diagnosis is made by histological examination in previous. According to the 2015 ESC/ERS Guidelines, detection of a mutation in the eukaryotic translation initiation factor 2 alpha kinase 4 (EIF2AK4) without histological confirmation is recommended to validate the diagnosis of PVOD...
September 2016: Medicine (Baltimore)
Peter Seizer, Michaela Rockenstiehl, Suzanne Fateh-Moghadam, Susanne Haen, Ferruh Artunc, Martin R Müller, Azadeh Ebrahimi, Reimer Riessen, Meinrad Gawaz, Falko Fend, Michael Haap
HISTORY AND ADMISSION FINDINGS: A 55-year old man suffers from progressive, distinctive dyspnoea and physical weakness since 5 days. Due to ST-segment changes in the ECG and a positive troponin-test, the primary care physician initiates an hospitalization. INVESTIGATIONS: After admission, the laboratory tests confirm the elevated troponin-values, and show additionally elevated pro-brain-natriuric-peptide-values. The coronary angiography presents a highly reduced left ventricular function, an aortic insufficiency III° and a coronary heart disease...
September 2016: Deutsche Medizinische Wochenschrift
Tamás Forster
The new 2015 ESC/ERS Guideline refined the diagnostic criteria of pulmonary hypertension. A new diagnostic algorithm is suggested. The therapeutic algorithm is renewed on the basis of newly registered drugs. Besides the usual sequential combination, the immediate (initial) combination is proposed as an alternative way. Pulmonary hypertension should be treated in expert referral centers. Orv. Hetil., 2016, 157(38), 1522-1525.
September 2016: Orvosi Hetilap
L Eckardt, T Deneke
The 2015 European Society of Cardiology Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death is an update of the former 2006 European/American guidelines. This new consensus document gives a detailed overview on prevention and therapy of ventricular arrhythmias and sudden cardiac death. This includes detailed discussion of channelopathies and various cardiomyopathies. Gaps in evidence are identified and also discussed. DNA analysis and postmortem assessment in sudden cardiac death victims is for the first time part of these new recommendations...
September 2016: Herzschrittmachertherapie & Elektrophysiologie
M J Pekka Raatikainen, David O Arnar, Bela Merkely, A John Camm, Gerhardt Hindricks
AIMS: The aim of this analysis was to provide comprehensive information on the access to and use of cardiac implantable electronic device (CIED) and catheter ablation therapy in the European Society of Cardiology (ESC) area. METHODS AND RESULTS: The European Heart Rhythm Association (EHRA) has been collecting descriptive and quantitative data on invasive arrhythmia therapies since 2008. This year 50 of the 56 ESC member countries provided data for the EHRA White Book...
August 2016: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
A Tofield
No abstract text is available yet for this article.
December 21, 2015: European Heart Journal
Jelena Pavlovic, Philip Greenland, Jaap W Deckers, Jasper J Brugts, Maryam Kavousi, Klodian Dhana, M Arfan Ikram, Albert Hofman, Bruno H Stricker, Oscar H Franco, Maarten J G Leening
IMPORTANCE: The American College of Cardiology/American Heart Association (ACC/AHA) and the European Society of Cardiology (ESC) guidelines both recommend lipid-lowering treatment for primary prevention based on global risk for cardiovascular disease (CVD). However, randomized clinical trials (RCTs) for statin use have included participants with specific risk-factor profiles. OBJECTIVE: To evaluate the overlap between the ACC/AHA and ESC guideline recommendations and available evidence from RCTs for statin use in primary prevention of CVD...
September 1, 2016: JAMA Cardiology
Jerry C Lee, Tomasz Zdrojewski, Michael J Pencina, Adam Wyszomirski, Mateusz Lachacz, Grzegorz Opolski, Piotr Bandosz, Marcin Rutkowski, Zbigniew Gaciong, Bogdan Wyrzykowski, Ann M Navar
IMPORTANCE: The American College of Cardiology/American Heart Association (ACC/AHA) guidelines for the management of blood cholesterol and the current European Society of Cardiology/European Atherosclerosis Society (ESC/EAS) guidelines differ in how they identify adults in need of statin therapy; furthermore, it is unclear how this difference translates into numbers and characteristics of patients recommended for treatment. OBJECTIVE: To determine the effect of the ACC/AHA and ESC/EAS cholesterol guidelines when applied to a population-based sample...
September 1, 2016: JAMA Cardiology
Marco Roffi, Christian Müller, Marco Valgimigli, Stephan Windecker, Baris Gencer
The 2015 non-ST-segment elevation acute coronary syndromes guidelines of the European Society of Cardiology have been published 4 years after the previous edition. A new algorithm was presented for the diagnosis of acute myocardial infarction based on the measurement of high-sensitivity cardiac troponin levels at presentation and at 1 hour, including a guidance on the duration of cardiac rhythm monitoring. New recommendations address the management of antiplatelet therapy regarding duration of dual antiplatelet therapy, in patients requiring long-term anticoagulation or undergoing urgent coronary artery bypass surgery as well as of acute bleeding events related to antithrombotics...
May 25, 2016: Revue Médicale Suisse
Fatima Rodriguez, Kenneth W Mahaffey
Non-ST-segment elevation acute coronary syndromes (NSTE-ACS) are the leading cause of morbidity and mortality from cardiovascular disease worldwide. The American Heart Association/American College of Cardiology and the European Society of Cardiology periodically release practice guidelines to guide clinicians in the management of NSTE-ACS, most recently in in 2014 and 2015, respectively. The present review compares and contrasts the 2 guidelines, with a focus on the strength of recommendation and level of evidence in the approach to initial presentation and diagnosis of NSTE-ACS, risk assessment, treatments, and systems of care...
July 19, 2016: Journal of the American College of Cardiology
Atsushi Sugiura, Nobusada Funabashi, Koya Ozawa, Yoshio Kobayashi
PURPOSE: We investigated the relationship of left ventricular (LV) diastolic dysfunction and LV mass index (LVMI) against pulmonary hypertension (PH) in systemic autoimmune disease (SAD). METHODS: A total of 84 SAD patients (68 females; 53±17years; systemic lupus erythematosus, 27%; scleroderma, 17%; vasculitis, 16%; mixed connective tissue disease, 13% and polymyositis/dermatomyositis complex, 10%) without significant pericardial effusion (PE) on TTE (Vivid E9, GE) were analyzed...
October 1, 2016: International Journal of Cardiology
Sandrine Charpentier, Camille Chenevier-Gobeaux
High sensitivity cardiac troponins must be used in first intention. H0/H3 algorithm is recommended in the diagnostic strategy. In total, 75% of emergency patients can be early discharged with the H0/H1 algorithm. Interpretation of troponin values requires taking into account the clinical context and electrocardiogram. The algorithm H0/H1 cannot be used for early presenters in ED after onset of chest pain. Further validation studies are needed before widespread application of H0/H1 algorithm.
June 30, 2016: La Presse Médicale
B Plicht, A Lind, R Erbel
Infective endocarditis is an endovascular infection usually caused by bacteria. Mortality rate is still approximately 20 %. To improve patients' prognosis by implementation of current diagnostic and therapeutic evidence, the European Society of Cardiology published an updated version of the guidelines for management of infective endocarditis in 2015. It strengthens the role of imaging modalities like PET/CT for detection of infectious foci when echocardiography remains negative and highlights the use of modern tests for identification of possible pathogens...
July 2016: Der Internist
Hein Heidbuchel, Peter Verhamme, Marco Alings, Matthias Antz, Hans-Christoph Diener, Werner Hacke, Jonas Oldgren, Peter Sinnaeve, A John Camm, Paulus Kirchhof
In 2013, the European Heart Rhythm Association (EHRA) published a Practical Guide on the use of non-VKA oral anticoagulants (NOACs) in patients with atrial fibrillation (AF) (Heidbuchel H, Verhamme P, Alings M, Antz M, Hacke W, Oldgren J, Sinnaeve P, Camm AJ, Kirchhof P, European Heart Rhythm A. European Heart Rhythm Association Practical Guide on the use of new oral anticoagulants in patients with non-valvular atrial fibrillation. Europace 2013;15:625-651; Heidbuchel H, Verhamme P, Alings M, Antz M, Hacke W, Oldgren J, Sinnaeve P, Camm AJ, Kirchhof P...
June 9, 2016: European Heart Journal
Willibald Hochholzer, Franz-Josef Neumann
In 2015 the European Society of Cardiology published a new version of the guidelines for the management of acute coronary syndromes without persistent ST-segment elevation. The current communication addresses some of the most important updates: introduction of the 1-hour diagnostic algorithm with high-sensitivity troponin assays, specified time lines for the invasive strategy, new recommendations for catheter intervention and peri-interventional antithrombotic therapy as well as new aspects of secondary prevention...
June 2016: Deutsche Medizinische Wochenschrift
Camille Chenevier-Gobeaux, Christophe Meune, Guillaume Lefevre, Benoit Doumenc, Emmanuel Sorbets, Nicolas Peschanski, Patrick Ray
BACKGROUND: Recent 2015 ESC recommendations for the management of patients with suspected acute myocardial infarction (AMI) support that a single value of high-sensitivity cardiac troponin (HS-cTn) measured at presentation could rule out AMI if below the limit of blank (LoB) or detection (LoD). OBJECTIVES: We aimed to evaluate whether an undetectable HS-cTnT at presentation safely rules out NSTEMI in unselected patients with chest pain. PATIENTS AND METHODS: This is a post hoc analysis of two prospective cohorts with similar design that included patients suspected of AMI at three French university hospitals...
May 24, 2016: Clinical Biochemistry
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"