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https://www.readbyqxmd.com/read/28551933/-recommendations-for-the-diagnosis-and-management-of-pediatric-acute-gastroenteritis-in-israel-update-2017
#1
Firas Rinawi, Shai Ashkenazi, Michael Wilschanski, Eli Somekh, Raanan Shamir
AIMS: The aim of these guidelines is to update and extend evidence-based recommendations for the diagnosis and management of children with acute gastroenteritis (AGE) in Israel, based on new data and the recently published European update. METHODS: The recommendations, which are based on a systematic review of the literature, were graded by the level of evidence. The guidelines were endorsed by the Israeli societies for Pediatric Gastroenterology, Pediatric Infectious Diseases and the Israeli Association of Pediatrics...
March 2017: Harefuah
https://www.readbyqxmd.com/read/28551905/-molecular-markers-for-prostate-cancer
#2
REVIEW
Dov Engelstein
Prostate cancer (PCa) is the most frequent malignancy and the second cause of death from malignancy in men in the Western world. Prostatic Specific Antigen (PSA) has been widely used as a possible marker for PCa for the last three decades, but its significant limitations are known, especially its lack of an exact cutoff level for diagnosis of PCa. Imprudent use of PSA has led to over-diagnosis and over-treatment in men with low risk PCa, not significant for survival. Therefore, researchers are looking for better and more accurate markers for diagnosis, treatment decisions and follow-up...
May 2017: Harefuah
https://www.readbyqxmd.com/read/28551829/meta-analysis-of-the-effects-of-genetic-polymorphisms-on-intervertebral-disc-degeneration
#3
J Rigal, A Léglise, T Barnetche, A Cogniet, S Aunoble, J C Le Huec
INTRODUCTION: Chronic low back pain is a significant public health issue. Both its direct and indirect cost represents tens of billions of US dollars. Although chronic low back pain can be the result of many factors, the predominant cause is disc degeneration. Recent studies have shown genetic involvement in up to 74% of cases. This study aimed to evaluate genetic risk factors of disc degeneration by performing a systematic analysis of association studies. The objective is to provide a guide for practice by assessing the clinical relevance of current information...
May 27, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28551759/seeing-a-brain-through-an-other-the-informant-s-share-in-the-diagnosis-of-dementia
#4
Laurence Anne Tessier
This article takes up the neuroscientific assumption of our brains as "solitary" and contrasts this understanding with the description of actual clinical practices. Drawing on observations of clinical consultations and team meetings in a world famous US center for the diagnosis of dementia, I examine how the "informant", a member of the patient's family, participates in the diagnosis process. Based on specific situations in which the informant is judged to be a "bad" one, I inquire as to how clinicians use what they understand of the affective relationships between the patient and the bad informant in order to make a diagnosis...
May 27, 2017: Culture, Medicine and Psychiatry
https://www.readbyqxmd.com/read/28551477/an-evaluation-of-approaches-used-to-teach-quality-improvement-to-pre-registration-healthcare-professionals-an-integrative-review
#5
REVIEW
Lorraine Armstrong, Ashley Shepherd, Fiona Harris
BACKGROUND: Improving the quality of healthcare remains central to UK and international policy, practice and research. In 2003, The Institute of Medicine's 'Health Professions Education: A Bridge to Quality', advocated quality improvement as a core competency for all healthcare professionals. As a result, developing capacity and capability of those applying improvement methodologies in the pre-registration population has risen, yet, little is known about the teaching approaches employed for this purpose...
May 22, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/28551410/perceptions-and-attitudes-of-community-pharmacists-toward-professional-ethics-and-ethical-dilemmas-in-the-workplace
#6
Jadranka Vuković Rodríguez, Živka Juričić
BACKGROUND: Formal training in pharmacy ethics is relatively new in Croatia, and the professional code of ethics is more than 20 years old. Very little is known about how practicing pharmacists implement ethical considerations and relevant professional guidelines in their work. OBJECTIVES: This study aimed to provide the first description of the perceptions and attitudes of Croatian community pharmacists toward ethics in pharmacy practice, how often they face certain ethical dilemmas and how they resolve them...
May 22, 2017: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/28551400/correlation-between-screening-mammography-interpretive-performance-on-a-test-set-and-performance-in-clinical-practice
#7
Diana L Miglioretti, Laura Ichikawa, Robert A Smith, Diana S M Buist, Patricia A Carney, Berta Geller, Barbara Monsees, Tracy Onega, Robert Rosenberg, Edward A Sickles, Bonnie C Yankaskas, Karla Kerlikowske
RATIONALE AND OBJECTIVES: Evidence is inconsistent about whether radiologists' interpretive performance on a screening mammography test set reflects their performance in clinical practice. This study aimed to estimate the correlation between test set and clinical performance and determine if the correlation is influenced by cancer prevalence or lesion difficulty in the test set. MATERIALS AND METHODS: This institutional review board-approved study randomized 83 radiologists from six Breast Cancer Surveillance Consortium registries to assess one of four test sets of 109 screening mammograms each; 48 radiologists completed a fifth test set of 110 mammograms 2 years later...
May 24, 2017: Academic Radiology
https://www.readbyqxmd.com/read/28551364/barriers-and-attitudes-to-research-among-residents-in-plastic-and-reconstructive-surgery-a-national-multicenter-cross-sectional-study
#8
The Canadian Plastic Surgery Research, Sarah Al Youha, Becher Alhalabi, Jill Stone, Helene Retrouvey, Osama Samargandi, Johnny Ionut Efanov, Michael Stein, Alexander Morzycki, Haley Augustine, Emilie Bougie, Diana Song, Hollie Power, Julian Diaz-Abele, Caitlin Symonette, Marie Noland, Chris Coroneos, Sophocles Voineskos, Joshua Vorstenbosch, Toni Zhong, Michael Bezuhly, Jason G Williams
OBJECTIVE: Research sets the foundation for developing plastic surgeons who think critically and approach clinical practice with an inquisitive mind. The objective of this study was to characterize current attitudes and perceived barriers towards conducting research during residency. DESIGN: A validated 36-item questionnaire was developed by a national task-force of Canadian plastic surgery trainees. The survey was distributed to all 13 plastic surgery programs in Canada...
May 24, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/28551301/hybrid-imaging-with-pet-mri-ready-for-clinical-routine
#9
EDITORIAL
Jiří Ferda
The introduction of integrated PET/MRI imaging combining full magnetic resonance imaging and positron emission tomography is a new milestone in tissue imaging. As usual innovations in clinical practice generate new dilemmas. The questions it poses are: when to use PET/MRI scanning, what radiopharmaceutical to use and how to optimize examination protocols. A range of new radiopharmaceuticals, in addition to 18F-fluorodeoxyglucose (18F-FDG), are now available for assessing and characterizing tissues.
May 9, 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28551282/bowel-bladder-dysfunction-and-numbness-in-the-sole-of-the-both-feet-in-lumbar-spinal-stenosis-a-multicenter-cross-sectional-study
#10
Kazuyuki Watanabe, Miho Sekiguchi, Koji Yonemoto, Takuya Nikaido, Kinshi Kato, Koji Otani, Shoji Yabuki, Tatsuyuki Kakuma, Shin-Ichi Kikuchi, Shin-Ichi Konno
BACKGROUND: Numbness in the soles of both feet at rest or bowel/bladder dysfunction can occur in patients with lumbar spinal stenosis (LSS), especially in patients with cauda equina lesions. The purpose of this study was to clarify the relationship between cauda equina symptoms at rest and quality of life (QOL) in LSS patients using standardized questionnaires developed for the Japanese population. METHODS: A survey was conducted in 564 hospitals and general practice clinics nationwide from December 1, 2011 to December 31, 2012...
May 24, 2017: Journal of Orthopaedic Science: Official Journal of the Japanese Orthopaedic Association
https://www.readbyqxmd.com/read/28551175/long-term-survival-of-subcutaneous-anti-tumor-necrosis-factor-biological-drugs-administered-between-2008-and-2012-in-a-cohort-of-rheumatoid-arthritis-patients
#11
Noelia Alvarez Rivas, Tomas R Vazquez Rodriguez, Jose A Miranda Filloy, Carlos Garcia-Porrua, Amalia Sanchez-Andrade Fernández
OBJECTIVE: To compare the survival of subcutaneous anti-tumor necrosis factor (TNF) drugs used between 2008 and 2012 prescribed in accordance with clinical practice. MATERIAL AND METHODS: Retrospective, observational study of the patients in our center diagnosed with rheumatoid arthritis (RA). We included patients who had received a subcutaneous anti-TNF agent for at least 6 months. The data were analyzed using the SPSS V17.0 statistical package. RESULTS: Forty-nine RA patients started subcutaneous biological treatment with an anti-TNF agent (32 with etanercept and 17 with adalimumab)...
May 25, 2017: Reumatología Clinica
https://www.readbyqxmd.com/read/28551053/socio-environmental-risk-factors-for-medically-attended-agricultural-injuries-in-wisconsin-dairy-farmers
#12
Jeffrey J VanWormer, Kathrine L Barnes, Stephen C Waring, Matthew C Keifer
BACKGROUND: Accidents are common in the agricultural industry, particularly among dairy farmers. How said farmers get hurt is well established, but far less is known about how distal, socio-environmental factors influence injuries. This study examined associations between medically-attended agricultural injuries and: (1) personal sociodemographic characteristics, and (2) farm environment features and general safety practices. METHODS: A cross-sectional survey was implemented with linked data from electronic health records on prior agricultural injuries that occurred between 01/01/2002-12/31/2015...
May 21, 2017: Injury
https://www.readbyqxmd.com/read/28551032/recommendations-for-the-use-of-everolimus-in-de-novo-kidney-transplantation-false-beliefs-myths-and-realities
#13
Julio Pascual, Fritz Diekmann, Constantino Fernández-Rivera, Gonzalo Gómez-Marqués, Alex Gutiérrez-Dalmau, María José Pérez-Sáez, Asunción Sancho-Calabuig, Federico Oppenheimer
The immunosuppressive combination most commonly used in de novo kidney transplantation comprises a calcineurin inhibitor (CI), tacrolimus, a mycophenolic acid derivative and steroids. The evidence which underlies this practice is based in the Symphony trial with controlled follow-up of one year, in which no comparator group included the combination CI-mTOR inhibitor. Different high-quality clinical trials support the use of everolimus as a standard immunosuppressive drug associated with reduced exposure of a CI in kidney transplantation...
May 24, 2017: Nefrología: Publicación Oficial de la Sociedad Española Nefrologia
https://www.readbyqxmd.com/read/28551002/development-of-a-computer-interpretable-clinical-guideline-model-for-decision-support-in-the-differential-diagnosis-of-hyponatremia
#14
Arturo González-Ferrer, M Ángel Valcárcel, Martín Cuesta, Joan Cháfer, Isabelle Runkle
INTRODUCTION: Hyponatremia is the most common type of electrolyte imbalance, occurring when serum sodium is below threshold levels, typically 135mmol/L. Electrolyte balance has been identified as one of the most challenging subjects for medical students, but also as one of the most relevant areas to learn about according to physicians and researchers. We present a computer-interpretable guideline (CIG) model that will be used for medical training to learn how to improve the diagnosis of hyponatremia applying an expert consensus document (ECDs)...
July 2017: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/28550982/early-provision-of-oropharyngeal-colostrum-leads-to-sustained-breast-milk-feedings-in-preterm-infants
#15
Ruth Snyder, Aimee Herdt, Nancy Mejias-Cepeda, John Ladino, Kathryn Crowley, Philip Levy
BACKGROUND: Oropharyngeal colostrum (OC) application strategies have been shown to be feasible and safe for very low birth weight (VLBW) infants. Evidence to support the nutritional and clinical advantages of OC care remains somewhat theoretical. The objectives of this study were to a) confirm the feasibility and safety of OC application in preterm infants and b) determine if OC application is associated with improved nutritional and clinical outcomes from birth to discharge. We hypothesized that OC application in the first few days would promote sustained breast milk feedings through discharge...
May 10, 2017: Pediatrics and Neonatology
https://www.readbyqxmd.com/read/28550968/clinical-audits-to-improve-critical-care-part-1-prepare-and-collect-data
#16
Amanda J Ullman, Gillian Ray-Barruel, Claire M Rickard, Marie Cooke
Clinical audits are used to examine current practice, compare this with established best practice and implementing change, to ensure patients receive the most effective treatment. They are successful in improving the quality and safety of care provided, and thereby clinical outcomes. Clinical audits are ubiquitous throughout critical care practice, but without the necessary focus, engagement, preparation, method, evaluation and communication, they may be a waste of resources. This article is the first of a two-paper series regarding audits in critical care...
May 24, 2017: Australian Critical Care: Official Journal of the Confederation of Australian Critical Care Nurses
https://www.readbyqxmd.com/read/28550925/use-of-a-pedicled-omental-flap-to-reduce-inflammation-and-vascularize-an-abdominal-wall-patch
#17
Takafumi Uchibori, Keisuke Takanari, Ryotaro Hashizume, Nicholas J Amoroso, Yuzuru Kamei, William R Wagner
BACKGROUND: Although a variety of synthetic materials have been used to reconstruct tissue defects, these materials are associated with complications such as seromas, fistulas, chronic patient discomfort, and surgical site infection. While alternative, degradable materials that facilitate tissue growth have been examined. These materials can still trigger a foreign body inflammatory response that can lead to complications and discomfort. MATERIALS AND METHODS: In this report, our objective was to determine the effect of placing a pedicled omental flap under a biodegradable, microfibrous polyurethane scaffold serving as a full-wall thickness replacement of the rat abdominal wall...
May 15, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28550915/evaluation-of-four-mesh-fixation-methods-in-an-experimental-model-of-ventral-hernia-repair
#18
Grigoris Chatzimavroudis, Stylianos Kalaitzis, Nikolaos Voloudakis, Stefanos Atmatzidis, Spyridon Kapoulas, Ioannis Koutelidakis, Basilis Papaziogas, Emmanouil C Christoforidis
BACKGROUND: The present animal study was conducted to comparably investigate the performance of four different fixation techniques of intraperitoneally implanted meshes. MATERIALS AND METHODS: Fifteen New Zealand white rabbits were used. In each animal, four abdominal wall defects were created and repaired with four pieces of intraperitoneal mesh (Parietex Composite), fixed with nonabsorbable (titanium) spiral tacks (group A), absorbable (lactic and glycolic acid co-polymer) screw-type tacks (group B), transfascial polypropylene sutures (group C), or fibrin glue (group D)...
May 15, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28550855/summary-of-evidence-about-complications-of-computer-engineered-complete-dentures-is-not-useful-for-informing-clinical-practice
#19
Romina Brignardello-Petersen
No abstract text is available yet for this article.
June 2017: Journal of the American Dental Association
https://www.readbyqxmd.com/read/28550759/venous-thromboembolism-in-the-elderly-a-narrative-review
#20
REVIEW
T Tritschler, D Aujesky
Persons aged ≥65years not only account for over 60% of venous thromboembolism (VTE) events, they have also a higher mortality and VTE-related morbidity than younger patients, including anticoagulation-related bleeding and the postthrombotic syndrome. However, only few studies have focused specifically on VTE in older persons and practice guidelines commonly extrapolate study results from younger healthier patients to the multimorbid elderly. Evidence suggests that the clinical presentation is more subtle in the elderly with VTE and that commonly used diagnostic modalities, including clinical prediction rules, D-dimer tests, and planar ventilation-perfusion scans are less specific and efficient in older persons...
May 17, 2017: Thrombosis Research
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