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HPV in men

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https://www.readbyqxmd.com/read/29771378/detection-of-incident-anal-high-risk-hpv-dna-in-msm-incidence-or-reactivation
#1
Denise E Twisk, Marianne A B van der Sande, Arne van Eeden, Daniëlle A M Heideman, Fiona R M van der Klis, Henry J C de Vries, Maarten F Schim van der Loeff
Background: We aimed to assess whether sexual exposure may explain all incident anal HPV detections among men who have sex with men (MSM). Methods: A longitudinal study among MSM was conducted between 2010 and 2013 with six-monthly visits and up to 24 months of follow-up. Risk-factor questionnaires, blood samples, and anal and penile self-swabs were collected at each visit. Self-swabs were used for detection and genotyping of HPV by SPF10-PCR/DEIA/LiPA25 system...
May 16, 2018: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29759898/risk-factors-for-human-papillomavirus-detection-in-urine-samples-of-heterosexual-men-visiting-urological-clinics-in-japan
#2
Kazufumi Nakashima, Kazuyoshi Shigehara, Tadaichi Kitamura, Hiroshi Yaegashi, Masayoshi Shimamura, Shohei Kawaguchi, Kouji Izumi, Yoshifumi Kadono, Atsushi Mizokami
OBJECTIVE: The present study aimed to investigate human papillomavirus (HPV) prevalence and identify risk factors for HPV detection in urine samples among heterosexual men attending urological clinics. MATERIALS AND METHODS: Spot urine samples including initial stream were collected from 845 participants, and the cell pellets were preserved into liquid-based cytological solution. After DNA extraction from each sample, HPV-DNA amplification and genotyping were performed using Luminex multiplex polymerase chain reaction...
May 11, 2018: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/29757775/development-and-calibration-of-a-mathematical-model-of-anal-carcinogenesis-for-high-risk-hiv-infected-men
#3
Emily A Burger, Michael A Dyer, Stephen Sy, Joel M Palefsky, Alexandra De Pokomandy, François Coutlee, Michael J Silverberg, Jane J Kim
OBJECTIVES: Men who have sex with men (MSM) who are living with human immunodeficiency virus (HIV) are at highest risk for anal cancer. Our objective was to use empirical data to develop a comprehensive disease simulation model that reflects the most current understanding of anal carcinogenesis, which is uniquely positioned to evaluate future anal cancer screening strategies as well as provide insight on the unobservable course of the disease. SETTING: North America METHODS...
May 9, 2018: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/29750774/genital-wart-and-human-papillomavirus-prevalence-in-men-in-the-united-states-from-penile-swabs-results-from-national-health-and-nutrition-examination-surveys
#4
Michael Daugherty, Timothy Byler
INTRODUCTION: Human papillomavirus (HPV) is a common sexually transmitted infection in the United States that can lead to both malignant (high-risk) and benign (low-risk) findings. These low-risk findings include both genital condyloma, anal warts, and adult or juvenile papillomatosis, which are directly attributable to subtypes HPV 6 and HPV 11. We aim to estimate the prevalence of genital wart infections in men in the US population using a nationwide sample. METHODS: The NHANES database was queried for all men aged 18 to 59 years during the years 2013 to 2014...
June 2018: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/29749878/audit-of-a-human-papillomavirus-vaccine-programme-for-men-who-have-sex-with-men-delivered-through-an-integrated-sexual-reproductive-health-service
#5
Carys Knapper, Humphrey Birley, Irene Parker
Following the Joint Committee on Vaccination and Immunisation statement in November 2015 advising a human papillomavirus (HPV) vaccination programme targeting men who have sex with men (MSM) up to the age of 45 attending Genitourinary medicine and HIV services, we launched a HPV vaccination programme for MSM to be delivered through our Integrated Sexual Reproductive Health drop-in service across Newport and the South East Wales Valleys from 1 August 2016. Over the first 18 months of the vaccination programme 539 of the 693 (77%) eligible MSM who attended clinics where the vaccine was available commenced vaccination...
January 1, 2018: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/29747340/-the-impact-of-male-circumcision-on-the-natural-history-of-genital-hpv-infection-a-prospective-cohort-study
#6
F X Wei, M Guo, X J Ma, Y Huang, Y Zheng, L Wang, Y Sun, S J Zhuang, K Yin, Y Y Su, S J Huang, M Q Li, T Wu, J Zhang
Objective: To analyze the correlation between circumcision and incidence and clearance of male genital HPV infection. Methods: From May to July 2014, 18-55 year old men who had sexual behavior history were recruited from the general population in Liuzhou, Guangxi to set up a cohort. Totally, 113 circumcised and 560 uncircumcised men were enrolled and interviewed using a questionnaire (including information on demographic characteristics and sexual behaviors), then they were followed-up with 6-month interval for 2 times...
May 6, 2018: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/29743937/epidemiologic-and-economic-burden-of-hpv-diseases-in-spain-implication-of-additional-5-types-from-the-9-valent-vaccine
#7
Noelia López, Aureli Torné, Agustín Franco, María San-Martin, Elisabet Viayna, Carmen Barrull, Nuria Perulero
Background: A new nonavalent human papillomavirus (HPV) vaccine that includes genotypes 6/11/16/18/31/33/45/52/58 has been recently approved in Spain. A previous study has shown that attributable fraction of HPV related diseases in Spain is consistent with that reported in European and global studies. The aim of the present study was to estimate the annual direct costs associated to the following HPV-related diseases: genital warts, high grade precancerous lesions and cancer of cervix, vulva, vagina, anus and penis and head and neck cancer, caused by genotypes included in the nonavalent (9vHPV) and quadrivalent vaccines (4vHPV), in Spanish men and women...
2018: Infectious Agents and Cancer
https://www.readbyqxmd.com/read/29717924/prevalence-and-burden-related-to-genital-warts-in-india
#8
Uday S Khopkar, Murlidhar Rajagopalan, Anahita R Chauhan, Smita Kothari-Talwar, Puneet K Singhal, Karen Yee, Amit Kulkarni, Nuria Lara, Montserrat Roset, Anna R Giuliano, Suzanne M Garland
The prevalence of genital warts (GW) and self-reported human papillomavirus (HPV) as well as disease-related psychosocial impact among male and female patients aged 18-60 years in India were assessed. GW prevalence was estimated using a 2-week daily log of patients examined from June 7-September 22, 2011 by 200 participating physicians in 6 regions of India. Psychosocial impact was estimated using one-time, self-administered surveys, including HPV Impact Profile (HIP), Cuestionario Específico para Condiloma Acuminado ([Spanish] CECA; "Specific questionnaire for Condylomata Acuminata") and EuroQol-5 Dimension survey...
May 2, 2018: Viral Immunology
https://www.readbyqxmd.com/read/29715059/human-papillomavirus-vaccination-and-the-role-of-herd-effects-in-future-cancer-control-planning-a-review
#9
Talía Malagón, Cassandra Laurie, Eduardo L Franco
Vaccine herd effects are the indirect protection that vaccinated persons provide to those who remain susceptible to infection, due to the reduced transmission of infections. Herd effects have been an important part of the discourse on how to best implement human papillomavirus (HPV) vaccines and prevent HPV-related diseases. Areas covered: In this paper, we review the theory of HPV vaccine herd effects derived from mathematical models, give an account of observed HPV vaccine herd effects worldwide, and examine the implications of vaccine herd effects for future cervical cancer screening efforts...
May 1, 2018: Expert Review of Vaccines
https://www.readbyqxmd.com/read/29710215/rna-oncoimmune-phenotyping-of-hpv-positive-p16-positive-oropharyngeal-squamous-cell-carcinomas-by-nodal-status
#10
Wesley H Stepp, Douglas Farquhar, Siddharth Sheth, Angela Mazul, Mohammed Mamdani, Trevor G Hackman, D Neil Hayes, Jose P Zevallos
Importance: Clinical trials that deintensify treatment for patients with suspected human papillomavirus (HPV)-positive oropharyngeal squamous cell carcinoma (OPSCC) use p16 expression to identify HPV-mediated tumors and guide treatment. While p16 staining has a strong correlation with good outcomes, approximately 12% of p16-positive patients have recurrent disease. Biomarkers that reveal tumor-specific characteristics, such as nodal involvement, may change therapy decisions. Objective: To assess whether if a tumor-specific genetic signature exists for node-negative vs node-positive HPV 16-positive/p16-positive OPSCCs...
April 18, 2018: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/29708826/correlates-of-human-papillomavirus-hpv-vaccination-initiation-and-completion-among-18-26-year-olds-in-the-united-states
#11
Eric Adjei Boakye, Daphne Lew, Meera Muthukrishnan, Betelihem B Tobo, Rebecca L Rohde, Mark A Varvares, Nosayaba Osazuwa-Peters
PURPOSE: To examine correlates of HPV vaccination uptake in a nationally representative sample of 18-26-year-old adults. METHODS: Young adults aged 18-26 years were identified from the 2014 and 2015 National Health Interview Survey (n = 7588). Survey-weighted multivariable logistic regression models estimated sociodemographic factors associated with HPV vaccine initiation (≥1 dose) and completion (≥3 doses). RESULTS: Approximately 27% of study participants had initiated the HPV vaccine and 16% had completed the HPV vaccine...
April 30, 2018: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/29700009/human-papillomavirus-seroprevalence-and-association-with-anal-hpv-infection-and-squamous-intra-epithelial-lesions-in-australian-gay-and-bisexual-men
#12
Isobel M Poynten, Tim Waterboer, Fengyi Jin, David J Templeton, Richard J Hillman, Carmella Law, Alyssa Cornall, Sepehr Tabrizi, Jennifer M Roberts, Suzanne M Garland, Christopher K Fairley, Andrew E Grulich
BACKGROUND: Gay and bisexual men (GBM) are at disproportionately high risk of anal cancer. The precursor lesions, high grade squamous intra-epithelial lesions (HSIL) are very common and it is evident that not all HSIL progresses to cancer. The serological response to anal HPV in GBM has not been well characterised Methods:The Study of the Prevention of Anal Cancer is an ongoing cohort study of GBM aged 35 years and older. At six visits over three years, anal samples are collected for cytology, HPV DNA testing and histology...
April 26, 2018: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/29694716/anal-cytological-lesions-and-hpv-infection-in-individuals-at-increased-risk-for-anal-cancer
#13
Maria Gabriella Donà, Maria Benevolo, Alessandra Latini, Francesca Rollo, Manuela Colafigli, Mirko Frasca, Mauro Zaccarelli, Amalia Giglio, Domenico Moretto, Edoardo Pescarmona, Antonio Cristaudo, Massimo Giuliani
BACKGROUND: Anal cytology may be useful for evaluating lesions associated with human papillomavirus (HPV) in individuals at increased risk for anal cancer. METHODS: Liquid-based cytology was used to assess anal cytological lesions among human immunodeficiency virus (HIV)-infected and HIV-uninfected men who have sex with men (MSM). The Linear Array HPV genotyping test was used for HPV detection. RESULTS: This cross-sectional study included 1021 MSM, of whom 388 were HIV-infected (38...
April 25, 2018: Cancer Cytopathology
https://www.readbyqxmd.com/read/29673737/epidemiological-features-of-cancers-of-the-oral-cavity-oropharynx-hypopharynx-and-larynx-cancer-in-r%C3%A3-union-island
#14
A Delagranda, G Leterme, E Chirpaz, C Ferdynus, C Fernandez, F Rubin
INTRODUCTION: This study had two objectives: firstly, to identify and compare characteristics of cancer of the oral cavity, oropharynx, hypopharynx and larynx in Réunion Island, a tropical French overseas territory in the southern hemisphere; and secondly, to discuss how incidence of these cancers is presented in the international literature. MATERIAL AND METHOD: A retrospective study included 599 patients diagnosed with cancer of the oral cavity, oropharynx, hypopharynx or larynx between 2009 and 2013 in Réunion Island...
April 16, 2018: European Annals of Otorhinolaryngology, Head and Neck Diseases
https://www.readbyqxmd.com/read/29625768/human-papillomavirus-vaccine-acceptability-and-decision-making-among-adolescent-boys-and-parents-a-meta-ethnography-of-qualitative-studies
#15
REVIEW
Ashley Lacombe-Duncan, Peter A Newman, Philip Baiden
OBJECTIVE: Genital warts and human papillomavirus (HPV)-associated cancers in men can be substantially reduced through HPV vaccination; yet, globally, HPV vaccine uptake among boys remains low. This meta-ethnography synthesizes qualitative studies to understand, in-depth, HPV vaccine acceptability and decision-making among adolescent boys and/or their parents. METHODS: A systematic search identified qualitative studies examining HPV vaccines from the perspectives of boys and/or boys' parents...
April 3, 2018: Vaccine
https://www.readbyqxmd.com/read/29624559/risk-factors-for-oral-hpv-infection-among-young-men-who-have-sex-with-men-2-cities-united-states-2012-2014
#16
Sara E Oliver, Pamina Gorbach, Beau Gratzer, Martin Steinau, Tom Collins, Adam Parrish, Peter R Kerndt, Richard Crosby, Elizabeth R Unger, Lauri E Markowitz, Elissa Meites
BACKGROUND: Men who have sex with men (MSM) are at risk for cancers attributable to human papillomavirus (HPV), including oropharyngeal cancer. HPV vaccination is recommended for U.S. MSM through age 26 years. Oral HPV infection is associated with oropharyngeal cancer. We determined oral HPV prevalence and risk factors among young MSM. METHODS: The Young Men's HPV study enrolled MSM aged 18-26 years from clinics in Chicago and Los Angeles during 2012-2014. Participants self-reported demographics, sexual behaviors, vaccination and HIV status...
April 5, 2018: Sexually Transmitted Diseases
https://www.readbyqxmd.com/read/29589641/cutaneous-squamous-cell-carcinoma-complicating-hidradenitis-suppurativa-a-review-of-the-prevalence-pathogenesis-and-treatment-of-this-dreaded-complication
#17
Stephanie Chapman, Daniel Delgadillo III, Cara Barber, Amor Khachemoune
Hidradenitis suppurativa (HS) is a chronic and debilitating skin disorder characterized by the formation of painful abscesses, draining sinus tracts, and scarring, predominantly in skin folds such as the axillae and the perineum. The exact prevalence of HS is unknown because the disease is often underreported, but it has been estimated to be as high as 4.1%. HS is three times more prevalent in women than in men. Various comorbidities have been associated with HS, including inflammatory bowel disease and squamous cell carcinoma (SCC)...
March 2018: Acta Dermatovenerologica Alpina, Panonica, et Adriatica
https://www.readbyqxmd.com/read/29571270/human-papillomavirus-and-risk-of-prostate-cancer-a-systematic-review-and-meta-analysis
#18
Giorgio I Russo, Aldo E Calogero, Rosita A Condorelli, Guido Scalia, Giuseppe Morgia, Sandro La Vignera
BACKGROUND: There is growing evidence showing a putative association between high-risk human papillomavirus (HR-HPV) infection and an increased risk of PCa. OBJECTIVE: The aim of the current meta-analysis was to evaluate the association between HPV infection and PCa risk. METHODS: This analysis was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-analysis guidelines. We included all studies on HPV DNA or antibodies detected in biopsy tissues or sera...
March 23, 2018: Aging Male: the Official Journal of the International Society for the Study of the Aging Male
https://www.readbyqxmd.com/read/29558864/factors-protecting-male-and-female-adolescents-in-mexico-from-human-papillomavirus-infection
#19
Claudia Orozco Gómez, Jane Dimmitt Champion, María Guadalupe Moreno Monsiváis
INTRODUCTION: Adolescents may be infected with human papillomavirus (HPV) during their first sexual relationship. Persistent infections in adulthood may result in associated cancers among both women and men. This study explored condom use action plans, its influence on sexual activity in adolescents, and associated HPV protective behavior. METHODS: A descriptive correlational design was used. A convenience sample including adolescents ( N =313; male n = 171, female n = 142), aged 15 to 17 years, attending one of three public high schools in Mexico was recruited...
January 1, 2018: Hispanic Health Care International: the Official Journal of the National Association of Hispanic Nurses
https://www.readbyqxmd.com/read/29554238/prevalence-and-correlates-of-trichomonas-vaginalis-infection-among-men-and-women-in-the-united-states
#20
Eshan U Patel, Charlotte A Gaydos, Zoe R Packman, Thomas C Quinn, Aaron A R Tobian
Background: The epidemiology of Trichomonas vaginalis (TV) infection in the United States is poorly defined. Methods: Males and females aged 18-59 years who participated in the 2013-2014 National Health and Nutrition Examination Survey and provided a urine specimen were tested for TV infection (n = 4057). Participants were also examined for Chlamydia trachomatis (CT) infection, genital human papillomavirus (HPV) infection, and herpes simplex virus type 2 serostatus...
March 15, 2018: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
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