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https://www.readbyqxmd.com/read/28549147/prevalence-and-concordance-of-cutaneous-beta-human-papillomavirus-infection-at-mucosal-and-cutaneous-sites
#1
Shalaka S Hampras, Dana E Rollison, Anna R Giuliano, Sandrine McKay-Chopin, Lucia Minoni, Karen Sereday, Tarik Gheit, Massimo Tommasino
Background: Cutaneous beta human papillomavirus (HPV) infection across cutaneous and mucosal tissues within individuals has not been examined. Methods: A sub-cohort of men (n=87) participating in the 'HPV infection in men' (HIM) study provided eyebrow hairs, forearm skin swabs, genital skin swabs, oral rinse samples and anal swabs. Beta HPV DNA in the five tissues was detected using a multiplex assay and site-specific beta HPV prevalence was examined. Results: Any beta HPV was most prevalent in genital skin (81...
May 26, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28530494/review-anal-intraepithelial-neoplasia-in-hiv-infected-men-who-have-sex-with-men-is-screening-and-treatment-justified
#2
Peter Wasserman, David S Rubin, Glenn Turett
Anal squamous cell carcinoma (SCC) is the fourth most prevalent cancer in human immunodeficiency virus (HIV)-infected men who have sex with men (MSM). Human papillomavirus (HPV) has been detected in over 90% of anal carcinoma biopsy specimens from MSM, and is considered a necessary, but alone, insufficient factor for carcinogenesis. Anal intraepithelial neoplasia (AIN) may be precursive for SCC, and screening cytology with referral of persons with abnormality for high-resolution anoscopy-guided biopsy, and AIN treatment, has been recommended for prevention...
May 22, 2017: AIDS Patient Care and STDs
https://www.readbyqxmd.com/read/28525447/mothers-fathers-sons-and-human-papillomavirus-immunization-practices
#3
Tami Lynn Thomas, Ora L Strickland, Melinda Higgins
Despite the fact that human papillomavirus (HPV) infection and HPV-related cancers are on the rise in men, male HPV vaccine series completion is less than 10% in many areas. This study examined parental knowledge of the HPV vaccine and intent to vaccinate their sons. A cross-sectional study of 341 parents of boys was conducted in school settings in rural southeastern Georgia. Mothers were 2.07 times more likely than fathers to vaccinate their sons. Future research directions should include strategies to increase HPV vaccination in both genders and focus on parents' perceived severity and vulnerability of their sons to HPV infection...
July 2017: Family & Community Health
https://www.readbyqxmd.com/read/28515256/opportunities-and-challenges-human-papillomavirus-and-cancer
#4
Christina S Chu, David G Pfister
Mucosal exposure to human papillomavirus (HPV) can lead to anogenital and head and neck (H&N) cancer. Vaccination at a young age can be almost 100% effective in preventing HPV infection with the viral subtypes in both men and women, at least for disease in the anogenital tract. Therapeutic strategies targeting HPV in cervical dysplasia and cancer are showing promise as well in regressing dysplasia and controlling disease. That HPV-positive H&N cancer is a different disease from HPV-negative disease, with different molecular and clinical features and prognosis, is becoming better appreciated...
May 2017: Journal of the National Comprehensive Cancer Network: JNCCN
https://www.readbyqxmd.com/read/28514278/impact-of-screening-and-art-on-anal-cancer-incidence-in-hiv-positive-men-who-have-sex-with-men-mathematical-modeling-study
#5
Nello Blaser, Barbara Bertisch, Roger D Kouyos, Alexandra Calmy, Heiner C Bucher, Matthias Cavassini, Janne Estill, Olivia Keiser, Matthias Egger
BACKGROUND: The incidence of anal cancer is high in HIV-positive men who have sex with men (MSM). We modeled the impact of screening strategies and combination antiretroviral therapy (cART) coverage on anal cancer incidence in Switzerland. METHODS: Individual-based, dynamic simulation model parameterized with Swiss HIV Cohort Study (SHCS) and literature data. We assumed all men to be HPV infected. CD4 cell count trajectories were the main predictors of anal cancer...
May 16, 2017: AIDS
https://www.readbyqxmd.com/read/28505338/concordance-between-anal-and-oral-human-papillomavirus-hpv-infections-among-young-men-who-have-sex-with-men
#6
Martin Steinau, Pamina Gorbach, Beau Gratzer, Jim Braxton, Peter R Kerndt, Richard A Crosby, Elizabeth R Unger, Lauri E Markowitz, Elissa Meites
Prevalence of human papillomavirus (HPV) infections was assessed among 1033 young men who have sex with men (MSM) aged 18-26 years. HPV (any type) was detected in 742 (71.8%) anal specimens and 101 (9.8%) oral specimens. Although HPV was detected in specimens from both anatomical sites in 83 (8.0%) participants, type-specific concordance for at least one HPV type was found in only 35 (3.4%) participants. HIV and smoking were associated with higher prevalence at both sites and frequency of concordant types. Coinfections of identical HPV types were rare, suggesting independent infection events and/or different modes of clearance...
May 15, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28494533/awareness-of-and-attitudes-toward-human-papillomavirus-vaccination-among-adults-in-korea-9-year-changes-in-nationwide-surveys
#7
Jin-Kyoung Oh, Bo Yoon Jeong, E Hwa Yun, Min Kyung Lim
Purpose: Human papillomavirus (HPV) vaccination has been included in the National Immunization Program in Korea since 2016. We aimed to evaluate changes in the awareness of and attitudes toward HPV vaccination, among adults in Korea since the first introduction of the vaccines in 2007. Materials and Methods: A nationwide population-based survey was conducted in 2016 for 1200 nationally representative Korean men and women; the data obtained were compared with the data from the nationwide survey conducted in 2007...
May 10, 2017: Cancer Research and Treatment: Official Journal of Korean Cancer Association
https://www.readbyqxmd.com/read/28490581/patterns-of-prevalent-hpv-and-sti-co-infections-and-associated-factors-among-hiv-negative-young-western-cape-south-african-women-the-evri-trial
#8
Lynette J Menezes, Ubin Pokharel, Staci L Sudenga, Matthys H Botha, Michele Zeier, Martha E Abrahamsen, Richard H Glashoff, Susan Engelbrecht, Maarten F Schim van der Loeff, Louvina E van der Laan, Siegfried Kipping, Douglas Taylor, Anna R Giuliano
OBJECTIVE: To estimate the prevalence and describe the patterns of concurrent human papillomavirus (HPV) and STIs and associated factors among HIV-negative young Western Cape, South African women participating in the Efficacy of HPV Vaccine to Reduce HIV Infection (EVRI) trial. METHODS: HIV-negative women aged 16-24 years old were enrolled in the EVRI trial (NCT01489527) and randomised to receive the licensed four-valent HPV vaccine or placebo. At study entry, participants were clinically evaluated for five STIs: herpes simplex virus type 2 (HSV-2), chlamydia, gonorrhoea, syphilis and disease-causing HPV genotypes (6/11/16/18/31/33/35/39/45/51/52/56/58/59/68)...
May 10, 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28486774/dietary-intake-of-selected-nutrients-and-persistence-of-hpv-infection-in-men
#9
Raíssa do Vale C Lopes, Juliana A Teixeira, Dirce Marchioni, Luisa L Villa, Anna R Giuliano, Maria Luiza Baggio, Regina M Fisberg
Human papillomavirus (HPV) infection is a common sexually transmitted disease. Although often transitory, persistent oncogenic HPV infection may progress to a precursor lesion and, if not treated, can further increase the risk of cancer. The purpose of this study was to investigate the relation between dietary intake and HPV persistent infection in men of a Brazilian cohort. The study population consisted of 1,248 men from the Brazilian cohort of the HIM (HPV in Men) Study, ages 18 to 70 years, who completed a quantitative food frequency questionnaire...
May 9, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28485812/epidemiology-of-human-papillomavirus-on-anogenital-warts-in-portugal-the-hercoles-study
#10
J Azevedo, A Pista, C Lisboa, I Santo, L Azevedo, M J Cunhax
BACKGROUND: Anogenital warts (AGW) are one of the most prevalent sexually transmitted disease worldwide. Approximately 90% of AGWs are related to infection by HPV 6 and 11. However, AGW have been associated with infection by multiple genotypes, including HR-HPV, which may be associated with a long-term increased risk of anogenital cancer. OBJECTIVE: This observational prospective epidemiological study aims to estimate the type-specific HPV distribution on incident AGWs in both genders, and additionally to assess the frequency of anal and oral HPV infection in patients with AGWs...
May 9, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28483969/association-of-metabolic-syndrome-and-human-papillomavirus-virus-infection-in-men-and-women-residing-in-the-unites-states
#11
Jennifer C Molokwu, Eribeth Penaranda, David S Lopez, Alok Dwivedi, Christopher Dodoo, Navkiran Shokar
BACKGROUND: An estimated 33 percent of adults in the US have metabolic syndrome which has been associated with an increased risk for various cancer types. Theories of synergism among components of MetS that increase cancer risk via chronic inflammation and oxidative stress have been proposed. We hypothesize that men and women with MetS may have compromised immunological response resulting in increased risk for persistent HPV infection. The goal of this study is to determine the association of MetS with HPV types 6, 11, 16 and 18 and to explore variation of these associations by gender using data from a national survey...
May 8, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28480229/prevalence-and-transmission-of-beta-and-gamma-human-papillomavirus-in-heterosexual-couples
#12
Anna-Barbara Moscicki, Yifei Ma, Tarik Gheit, Sandrine McKay-Chopin, Sepideh Farhat, Lea E Widdice, Massimo Tommasino
BACKGROUND: Beta (β) and gamma (γ) human papillomavirus (HPV) are commonly found on the skin. Few of the β types are associated with nonmelanoma skin cancer. Little is known about transmission patterns of these HPV, specifically in the anogenital (AG) areas. The primary objective of this study was to examine the AG concordance and transmission of β and γHPV types between heterosexual couples. METHODS: Archival samples from a previously published study examining concordance of alpha HPV types between couples were tested for β and γHPV...
2017: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/28479047/the-analysis-of-expression-of-p16-protein-in-group-of-53-patients-treated-for-sinonasal-inverted-papilloma
#13
Roland Zydroń, Andrzej Marszałek, Magdalena Bodnar, Paweł Kosikowski, Grażyna Greczka, Małgorzata Wierzbicka
INTRODUCTION: Sinonasal Inverted Papilloma (IP) constitute relevant therapeutic problem due to destructive character of growth, tendency to recur and the possibility of malignant transformation. Therefore, many attempts to identify risk factors for IP occurrence have been undertaken, as well as research to find markers that would allow for the earlier detection of tumors and the application of adequate therapy. A widely known risk factor of IP is HPV infection. One of the markers of HPV infection and the ongoing effect of this change (although arousing some controversy) is the expression of the p16 protein...
April 19, 2017: Brazilian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/28467238/sexual-orientation-disparities-in-human-papillomavirus-vaccination-in-a-longitudinal-cohort-of-u-s-males-and-females
#14
Brittany M Charlton, Sari L Reisner, Madina Agénor, Allegra R Gordon, Vishnudas Sarda, S Bryn Austin
PURPOSE: This study sought to examine how human papillomavirus (HPV) vaccination may differ across sexual orientation groups (e.g., bisexuals compared to heterosexuals)-particularly in boys and men, about whom little is known. METHODS: Data were from a prospective cohort of 10,663 U.S. females and males enrolled in the Growing Up Today Study followed from 1996 to 2014. Participants were aged 11-24 years when the vaccine was approved for females in 2006 and 14-27 years when approved for males in 2009...
June 2017: LGBT Health
https://www.readbyqxmd.com/read/28463105/prevalence-of-hpv-in-adults-aged-18-69-united-states-2011-2014
#15
Geraldine McQuillan, Deanna Kruszon-Moran, Lauri E Markowitz, Elizabeth R Unger, Ryne Paulose-Ram
Data from the National Health and Nutrition Examination Survey Human papillomavirus (HPV) is the most common sexually transmitted infection in the United States (1). Some HPV types can cause genital warts and are considered low risk, with a small chance for causing cancer. Other types are considered high risk, causing cancer in different areas of the body including the cervix and vagina in women, penis in men, and anus and oropharynx in both men and women (2). This report provides the most recent national estimates of oral HPV prevalence among adults aged 18-69 from the National Health and Nutrition Examination Survey (NHANES) 2011-2014, as well as prevalence of genital HPV among adults aged 18-59 from NHANES 2013-2014...
April 2017: NCHS Data Brief
https://www.readbyqxmd.com/read/28456947/physician-communication-practices-as-a-barrier-to-risk-based-hpv-vaccine-uptake-among-men-who-have-sex-with-men
#16
Christopher W Wheldon, Steven K Sutton, Holly B Fontenot, Gwendolyn P Quinn, Anna R Giuliano, Susan T Vadaparampil
The Advisory Committee on Immunization Practices recommends that men who have sex with men (MSM) 26 years of age or younger be routinely vaccinated against HPV. For men outside of this risk-based population, the recommendation is routine vaccination until age 21. Thus, in order for this risk-based recommendation for MSM to be implemented, two distinct actions need to be completed during the clinical visit: (1) discuss recommendations for HPV vaccination with men and (2) assess sexual orientation to determine if a risk-based recommendation should be made...
April 29, 2017: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
https://www.readbyqxmd.com/read/28455577/-one-decade-of-hpv-vaccination-in-germany
#17
REVIEW
P Schneede
As a worldwide very common sexually transmitted infection (STI), HPV causes millions of genital warts every year and is responsible for 5% of all cancers in men and women. With strong empirical evidence for both vaccine safety and efficacy, the HPV vaccines proved to protect against these HPV-related conditions over the last decade. But current HPV vaccination coverage is suboptimal in many countries. Even in Germany the absence of a school-based immunization program and the recommendation of a publicly funded girls-only HPV vaccination strategy are the main reasons for a female coverage rate under 40%, which does not achieve herd immunity for the boys...
April 28, 2017: Der Urologe. Ausg. A
https://www.readbyqxmd.com/read/28446543/comparison-of-the-natural-history-of-genital-hpv-infection-among-men-by-country-brazil-mexico-and-the-united-states
#18
Staci L Sudenga, B Nelson Torres, Roberto Silva, Luisa L Villa, Eduardo Lazcano-Ponce, Martha Abrahamsen, Maria Luiza Baggio, Jorge Salmeron, Manuel Quiterio, Anna R Giuliano
BACKGROUND: Male genital HPV prevalence and incidence has been reported to vary by geographical location. Our objective was to assess the natural history of genital HPV by country among men with a median of 48 months of follow-up. METHODS: Men aged 18-70 years were recruited from US (n=1326), Mexico (n=1349), and Brazil (n=1410). Genital specimens were collected every six months and HPV genotyping identified 37 HPV genotypes. Prevalence of HPV was compared between the three countries using the Fisher's exact test...
April 26, 2017: Cancer Epidemiology, Biomarkers & Prevention
https://www.readbyqxmd.com/read/28437239/tprevalence-of-hpv-in-adults-aged-18-69-united-states-2011-2014
#19
Geraldine McQuillan, Deanna Kruszon-Moran, Lauri E Markowitz, Elizabeth R Unger, Ryne Paulose-Ram
Data from the National Health and Nutrition Examination Survey ● During 2011-2014, prevalence of any oral human papillomavirus (HPV) for adults aged 18-69 was 7.3%; high-risk HPV was 4.0%. ● Overall, prevalence of any and high-risk oral HPV was lowest among non-Hispanic Asian adults; any oral HPV was highest among non-Hispanic black adults. ● Prevalence of any and high-risk oral HPV was higher in men than women except for high-risk HPV among Asian adults. ● During 2013-2014, prevalence of any and high-risk genital HPV for adults aged 18-59 was 45...
April 2017: NCHS Data Brief
https://www.readbyqxmd.com/read/28432549/factors-associated-with-hpv-vaccination-in-young-males
#20
Kelli M Fuller, Leslie Hinyard
Human papilloma virus (HPV) affects both men and women; however, recommendations for HPV vaccination among men were not issued in the United States until 2011. The purpose of this study was to describe and compare characteristics of men who did and did not report receiving at least one dose of the HPV vaccine. Data from the ten states that completed the HPV vaccination module in the 2013 Behavioral Risk Factor Surveillance System (BRFSS) were included in the study. Young men ages 18-26 were included (N = 1624)...
April 21, 2017: Journal of Community Health
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