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Paul Sorajja

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https://www.readbyqxmd.com/read/29699609/1-year-outcomes-of-transcatheter-mitral-valve-replacement-in-patients-with-severe-mitral-annular-calcification
#1
Mayra Guerrero, Marina Urena, Dominique Himbert, Dee Dee Wang, Mackram Eleid, Susheel Kodali, Isaac George, Tarun Chakravarty, Moses Mathur, David Holzhey, Ashish Pershad, H Kenith Fang, Daniel O'Hair, Noah Jones, Vaikom S Mahadevan, Nicolas Dumonteil, Josep Rodés-Cabau, Nicolo Piazza, Enrico Ferrari, Daniel Ciaburri, Mohammed Nejjari, Augustin DeLago, Paul Sorajja, Firas Zahr, Vivek Rajagopal, Brian Whisenant, Pinak Bipin Shah, Jan-Malte Sinning, Adam Witkowski, Helene Eltchaninoff, Danny Dvir, Bena Martin, Guilherme F Attizzani, Diego Gaia, Nagela S V Nunes, Amir-Ali Fassa, Faraz Kerendi, Gregory Pavlides, Vijay Iyer, Georges Kaddissi, Christian Witzke, James Wudel, Gregory Mishkel, Bryan Raybuck, Chi Wang, Ron Waksman, Igor Palacios, Alain Cribier, John Webb, Vinnie Bapat, Mark Reisman, Raj Makkar, Martin Leon, Charanjit Rihal, Alec Vahanian, William O'Neill, Ted Feldman
BACKGROUND: The risk of surgical mitral valve replacement in patients with severe mitral annular calcification (MAC) is high. Several patients worldwide with severe MAC have been treated successfully with transcatheter mitral valve replacement (TMVR) using balloon-expandable aortic transcatheter valves. The TMVR in MAC Global Registry is a multicenter registry that collects data on outcomes of these procedures. OBJECTIVES: The goal of this study was to evaluate 1-year outcomes in this registry...
May 1, 2018: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29551454/diverse-perspectives-and-training-paths-in-cardiology-an-analysis-of-authorship-in-the-journal-of-the-american-college-of-cardiology
#2
Barbara A Danek, Aris Karatasakis, Judit Karacsonyi, Bavana V Rangan, Shuaib Abdullah, Paul Sorajja, Subhash Banerjee, Emmanouil S Brilakis
The role of women and foreign medical graduates in cardiology research published in the United States has received limited study. We examined the characteristics of the first and last authors of all original contributions and review articles published in the Journal of the American College of Cardiology from October 1, 2015 to October 1, 2016. A total of 345 articles were identified, with 687 first and last authors originating from ≥50 different countries. Overall 17% of authors were women (20% of first and 14% of last authors)...
March 15, 2018: Hellenic Journal of Cardiology: HJC, Hellēnikē Kardiologikē Epitheōrēsē
https://www.readbyqxmd.com/read/29501456/contemporary-management-of-ischemic-mitral-regurgitation-a-review
#3
REVIEW
Yader Sandoval, Paul Sorajja, Kevin M Harris
Ischemic mitral regurgitation occurs relatively frequently in patients with coronary artery disease and is associated with an increased long-term risk. The pathophysiology of ischemic mitral regurgitation is vexing and poses both diagnostic and therapeutic challenges, leading to the need for a comprehensive, multidisciplinary approach. The management is largely focused on medical therapy, and for those eligible, coronary revascularization or cardiac resynchronization therapy may be considered. In select patients, mitral valve surgery or catheter-based therapy may be undertaken with careful consideration of the underlying pathophysiology, surgical risk, and expected long-term outcomes...
February 28, 2018: American Journal of Medicine
https://www.readbyqxmd.com/read/29314592/impact-of-sleep-deprivation-on-the-outcomes-of-percutaneous-coronary-intervention
#4
Ann Iverson, Larissa Stanberry, Ross Garberich, Amber Antos, Yader Sandoval, M Nicholas Burke, Ivan Chavez, Mario Gössl, Timothy D Henry, Daniel Lips, Michael Mooney, Anil Poulose, Paul Sorajja, Jay Traverse, Yale Wang, Steven Bradley, Emmanouil S Brilakis
OBJECTIVES: This study sought to compare the clinical outcomes of percutaneous coronary interventions (PCIs) performed by sleep deprived and non-sleep deprived operators. BACKGROUND: Interventional cardiologists are at risk for sleep deprivation as they often have to perform emergent procedures at night, but the effects of sleep deprivation on clinical outcomes have received limited study. METHODS: We examined the frequency, clinical characteristics, and outcomes of daytime PCIs performed by sleep deprived and non-sleep deprived operators at a tertiary medical center...
January 3, 2018: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/29224709/prevalence-and-prognostic-significance-of-nonsustained-ventricular-tachycardia-in-patients-with-a-left-ventricular-ejection-fraction-from-35-to-50
#5
Sorcha M Allen, Victor A Abrich, Paul S Bibby, Daniel Fishman, Win-Kuang Shen, Dan Sorajja
The risk of life-threatening ventricular arrhythmias in patients with mild-to-moderately reduced left ventricular ejection fraction (LVEF) is unknown. This retrospective case-control study aims to identify the prevalence, risk factors, and outcomes associated with the development of nonsustained ventricular tachycardia (NSVT) as documented on permanent pacemakers or implantable loop recorders in tertiary care center patients with an LVEF of 35% to 50%. Data pertaining to patient demographics, previous medical history, heart failure functional class, echocardiographic parameters, and survival were compared between the groups...
February 1, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29207363/improvement-in-aortic-valve-area-in-patients-with-aortic-stenosis-through-use-of-a-new-hourglass-shaped-valvuloplasty-balloon
#6
Elizabeth Goldenberg, Wesley Pedersen, Emmanouil S Brilakis, Michael Mooney, Mario Gössl, Anil Poulose, Bilal Murad, James Kolbeck, Paul Sorajja
OBJECTIVES: The study aim was to assess the effect of hourglass-shaped V8 and TAV8 balloons (InterValve, Inc) on aortic valve area (AVA) and other outcomes in patients with severe aortic stenosis undergoing balloon aortic valvuloplasty (BAV). BAV has re-emerged with transcatheter therapy. Cylindrical balloons have been the device of choice despite limitations. The hourglass-shaped balloons, with shorter, broader segments separated by a narrowed waist, permit enhanced fixation and better leaflet opening without annular or sinotubular compromise...
December 2017: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/29169493/contemporary-arterial-access-in-the-cardiac-catheterization-laboratory
#7
REVIEW
Yader Sandoval, M Nicholas Burke, Angie S Lobo, Daniel L Lips, Arnold H Seto, Ivan Chavez, Paul Sorajja, Mazen S Abu-Fadel, Yale Wang, Anil Poulouse, Mario Gössl, Michael Mooney, Jay Traverse, David Tierney, Emmanouil S Brilakis
Obtaining femoral and radial arterial access in the cardiac catheterization laboratory using state-of-the-art techniques is essential to optimize outcomes, patient satisfaction, and procedural efficiency. Although transradial access is increasingly used for coronary angiography and percutaneous coronary intervention, femoral access remains necessary for numerous procedures, many requiring large-bore access, including complex high-risk coronary interventions, structural procedures, and procedures involving mechanical circulatory support...
November 27, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/29133070/percutaneous-treatment-for-native-mitral-regurgitation
#8
REVIEW
Paul Sorajja, Francesco Maisano
Severe mitral regurgitation (MR) confers an adverse prognosis, frequently with debilitating symptoms of heart failure. While open surgical correction has been the standard of care for decades, novel catheter-based technologies have emerged that are highly effective in the treatment of MR. These percutaneous technologies, which include methods for both repair as well as valve replacement, have the potential to address unmet clinical needs in patients with MR, and serve as a viable alternative to surgery.
November 2017: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/29102689/early-experience-with-new-transcatheter-mitral-valve-replacement
#9
Vinayak Bapat, Vivek Rajagopal, Christopher Meduri, R Saeid Farivar, Antony Walton, Stephen J Duffy, Robert Gooley, Aubrey Almeida, Michael J Reardon, Neal S Kleiman, Konstantinos Spargias, Stratis Pattakos, Martin K Ng, Michael Wilson, David H Adams, Martin Leon, Michael J Mack, Sharla Chenoweth, Paul Sorajja
BACKGROUND: Transcatheter mitral valve replacement (TMVR) is a potential therapy for patients with symptomatic, severe mitral regurgitation (MR). The feasibility of this therapy remains to be defined. OBJECTIVES: The authors report their early experience with TMVR using a new valve system. METHODS: The valve is a self-expanding, nitinol valve with bovine pericardial leaflets that is placed using a transapical delivery system. Patients with symptomatic MR who were deemed high or extreme risk by the local heart teams were enrolled in a global pilot study at 14 sites (United States, Australia, and Europe)...
January 2, 2018: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29096801/outcomes-with-transcatheter-mitral-valve-repair-in-the-united-states-an-sts-acc-tvt-registry-report
#10
Paul Sorajja, Sreekanth Vemulapalli, Ted Feldman, Michael Mack, David R Holmes, Amanda Stebbins, Saibal Kar, Vinod Thourani, Gorav Ailawadi
BACKGROUND: Post-market surveillance is needed to evaluate the real-world clinical effectiveness and safety of U.S. Food and Drug Administration-approved devices. OBJECTIVES: The authors examined the commercial experience with transcatheter mitral valve repair for the treatment of mitral regurgitation. METHODS: Data from the Society of Thoracic Surgery/American College of Cardiology Transcatheter Valve Therapy Registry on patients commercially treated with transcatheter mitral valve repair were analyzed...
November 7, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/29050627/outcomes-for-the-commercial-use-of%C3%A2-self-expanding-prostheses-in-transcatheter-aortic-valve-replacement-a-report-from-the-sts-acc-tvt-registry
#11
Paul Sorajja, Susheel Kodali, Michael J Reardon, Wilson Y Szeto, Stanley J Chetcuti, James Hermiller, Sharla Chenoweth, David H Adams, Jeffrey J Popma
OBJECTIVES: The authors sought to compare the outcomes of commercial transcatheter aortic valve replacement (TAVR) with the repositionable Evolut R platform to those observed with the CoreValve device in the Society of Thoracic Surgeons (STS)/American College of Cardiology (ACC) Transcatheter Valve Therapy (TVT) Registry. BACKGROUND: TAVR continues to evolve, with rapid adoption of iterative changes for commercial practice. Insight into the outcomes of this adoption is needed...
October 23, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28877303/association-of-guideline-adherence-for-serial-evaluations-with-survival-and-adverse-clinical-events-in-patients-with-asymptomatic-severe-aortic-stenosis
#12
Aisha Ahmed, Paul Sorajja, Ross F Garberich, R Saeid Farivar, Kevin M Harris, Mario Gössl
Importance: For patients with asymptomatic severe aortic stenosis and normal left ventricular function, current practice guidelines empirically recommend serial evaluations every 6 to 12 months. The benefit of this clinical monitoring is unknown. Objective: To determine the association of guideline adherence with clinical outcomes in patients with asymptomatic severe aortic stenosis. Design, Setting, and Participants: This retrospective cohort study involved 300 patients with asymptomatic severe aortic stenosis who were seen in the ambulatory Minneapolis Heart Institute at Abbott Northwestern Hospital...
October 1, 2017: JAMA Cardiology
https://www.readbyqxmd.com/read/28739812/transcatheter-therapy-for-mitral-regurgitation-clinical-challenges-and-potential-solutions
#13
REVIEW
Paul Sorajja, Martin B Leon, David H Adams, John G Webb, R Saeid Farivar
Severe mitral regurgitation is a common and complex disease that is associated with an adverse prognosis. For decades, surgical treatment has been the standard of care. Recently, multiple technologies for transcatheter mitral therapy have emerged, with the potential for both repair and replacement in patients with native mitral regurgitation. Transcatheter mitral technologies have potential as solutions for unmet clinical needs. Further rigorous clinical studies are needed to determine their efficacy and safety, as well as the appropriate patient candidates...
July 25, 2017: Circulation
https://www.readbyqxmd.com/read/28728695/alcohol-septal-ablation-for-obstructive-hypertrophic-cardiomyopathy-a-word-of-balance
#14
REVIEW
Paul Sorajja
The management of drug-refractory symptoms of obstructive hypertrophic cardiomyopathy has long been debated and is primarily centered on the choice between surgical myectomy and alcohol septal ablation. Decision making in these patients requires consideration of procedural risk, expertise and efficacy, and the long-term impact on patients' survival. Although there have been numerous reports on these procedures that may help guide decision making, these data continue to be self-reported and voluntary. Greater insight into the real-world experience for these therapies and how they should be applied in practice would be gained from mandatory reporting, akin to other multidisciplinary, transcatheter-based therapies...
July 25, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28707310/sleep-deprivation-in-interventional-cardiology-implications-for-patient-care-and-physician-health
#15
Yader Sandoval, Angie S Lobo, Virend K Somers, Kenneth Rosenfield, Steven M Bradley, Paul Sorajja, Peter Tajti, Emmanouil S Brilakis
The burden and impact of sleep deprivation on both patient care and on the health of interventional cardiologists is not well understood. Due to the nature of emergent procedures occurring in the cardiac catheterization laboratory, interventionalists are prone to suffer from acute and/or chronic sleep deprivation. Sleep deprivation has been associated with numerous adverse effects, such as impaired performance, cognitive deficits, reduced psychomotor vigilance, and workplace errors and injuries, among many others...
July 14, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28600086/invasive-hemodynamics-of-pericardial-disease
#16
REVIEW
Ganesh Athappan, Paul Sorajja
Pericardial diseases can be classified broadly as 3 entities: acute pericarditis, cardiac tamponade, and constrictive pericarditis. These disorders can be diagnosed and managed with noninvasive studies following a comprehensive history and physical examination, without the need for cardiac catheterization in most patients. Despite the advances in noninvasive cardiac imaging, there are limitations to their diagnostic accuracy. The invasive hemodynamic study offers the advantage of simultaneous, direct pressure measurement across multiple chambers, with direct examination of blood flow...
July 2017: Interventional Cardiology Clinics
https://www.readbyqxmd.com/read/28527769/severe-mitral-annular-calcification-first-experience-with-transcatheter-therapy-using-a-dedicated-mitral-prosthesis
#17
Paul Sorajja, Mario Gössl, Richard Bae, Lisa Tindell, John R Lesser, Judah Askew, R Saeid Farivar
No abstract text is available yet for this article.
May 11, 2017: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/28489331/scai-hfsa-clinical-expert-consensus-document-on-the-use-of-invasive-hemodynamics-for-the-diagnosis-and-management-of-cardiovascular-disease
#18
EDITORIAL
Paul Sorajja, Barry A Borlaug, Vasiliki V Dimas, James C Fang, Paul R Forfia, Michael M Givertz, Navin K Kapur, Morton J Kern, Srihari S Naidu
No abstract text is available yet for this article.
June 1, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28489324/executive-summary-of-the-scai-hfsa-clinical-expert-consensus-document-on-the-use-of-invasive-hemodynamics-for-the-diagnosis-and-management-of-cardiovascular-disease
#19
Paul Sorajja, Barry A Borlaug, Vivian Dimas, James C Fang, Paul R Forfia, Michael M Givertz, Navin K Kapur, Morton J Kern, Srihari S Naidu
No abstract text is available yet for this article.
June 1, 2017: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/28454731/executive-summary-of-the-scai-hfsa-clinical-expert-consensus-document-on-the-use-of-invasive-hemodynamics-for-the-diagnosis-and-management-of-cardiovascular-disease
#20
Michael M Givertz, James C Fang, Paul Sorajja, Vivian Dimas, Paul R Forfia, Navin K Kapur, Morton J Kern, Srihari S Naidu, Barry A Borlaug
No abstract text is available yet for this article.
June 2017: Journal of Cardiac Failure
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