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https://www.readbyqxmd.com/read/28721358/utah-optrode-array-customization-using-stereotactic-brain-atlases-and-3-d-cad-modeling-for-optogenetic-neocortical-interrogation-in-small-rodents-and-nonhuman-primates
#1
Ronald W Boutte, Sam Merlin, Guy Yona, Brandon Griffiths, Alessandra Angelucci, Itamar Kahn, Shy Shoham, Steve Blair
As the optogenetic field expands, the need for precise targeting of neocortical circuits only grows more crucial. This work demonstrates a technique for using Solidworks(®) computer-aided design (CAD) and readily available stereotactic brain atlases to create a three-dimensional (3-D) model of the dorsal region of area visual cortex 4 (V4D) of the macaque monkey (Macaca fascicularis) visual cortex. The 3-D CAD model of the brain was used to customize an [Formula: see text] Utah optrode array (UOA) after it was determined that a high-density ([Formula: see text]) UOA caused extensive damage to marmoset (Callithrix jacchus) primary visual cortex as assessed by electrophysiological recording of spiking activity through a 1...
October 2017: Neurophotonics
https://www.readbyqxmd.com/read/28715165/relaxing-school-suncreen-restrictions
#2
Joellen Kralik
(1) Utah, Delaware, Vermont, Minnesota and Idaho have the highest skin cancer rates of all U.S. states, according to the Centers for Disease Control and Prevention. (2) Sunscreen is regulated by the U.S. Food and Drug Administration because it makes a "drug claim"--that it helps prevent sunburn and decreases the risks of skin cancer and early skin aging caused by the sun. (3) In Europe and some other countries, sunscreens are regulated as cosmetics, not as drugs.
July 2017: NCSL Legisbrief
https://www.readbyqxmd.com/read/28695908/long-term-colorectal-cancer-incidence-after-negative-colonoscopy-in-the-state-of-utah-the-effect-of-family-history
#3
N Jewel Samadder, Lisa Pappas, Kenneth M Boucherr, Ken R Smith, Heidi Hanson, Alison Fraser, Yuan Wan, Randall W Burt, Karen Curtin
OBJECTIVES: Colonoscopy is widely recommended for colorectal cancer (CRC) screening, but evidence to guide the optimal frequency of repeat screening examination is limited. We examined the duration and magnitude of the risk of developing CRC, following a negative colonoscopy in those at average risk and those with a first-degree family history of CRC. METHODS: A cohort of Utah residents aged 50-80 years who had a negative colonoscopy between 1 January 2001 and 31 December 2011 was identified using the Utah Population Database...
July 11, 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28693347/improving-physician-communication-with-patients-as-measured-by-hcahps-using-a-standardized-communication-model
#4
Devin J Horton, Peter M Yarbrough, Nathan Wanner, Ryan D Murphy, Polina V Kukhareva, Kensaku Kawamoto
Physicians often fail to communicate well with patients. The objective of this retrospective controlled interrupted time series study was to evaluate the impact of a standardized communication intervention to improve physician communication. All patients ages 18 years or older (N = 7739 visits) admitted to University of Utah Health Care in Salt Lake City, Utah, from July 1, 2012, to June 31, 2014, were included. Obstetrics, rehabilitation, and psychiatric patients were excluded. The primary outcome was the percentage of patients who answered "Always" to all HCAHPS questions regarding physician-patient communication...
February 1, 2017: American Journal of Medical Quality: the Official Journal of the American College of Medical Quality
https://www.readbyqxmd.com/read/28688070/long-term-performance-of-porous-platinum-coated-neural-electrodes
#5
M Leber, R Bhandari, J Mize, D J Warren, M M H Shandhi, F Solzbacher, S Negi
Over the last several years, there has been a growing interest in neural implants for the study and diagnostics of neurological disorders as well as for the symptomatic treatment of central nervous system related diseases. One of the major challenges is the trade-off between small electrode sizes for high selectivity between single neurons and large electrode-tissue interface areas for excellent stimulation and recording properties. This paper presents an approach of increasing the real surface area of the electrodes by creating a surface microstructure...
September 2017: Biomedical Microdevices
https://www.readbyqxmd.com/read/28686718/morphological-variation-phylogenetic-relationships-and-geographic-distribution-of-the-baenidae-testudines-based-on-new-specimens-from-the-uinta-formation-uinta-basin-utah-usa
#6
Heather F Smith, J Howard Hutchison, K E Beth Townsend, Brent Adrian, Daniel Jager
We described newly discovered baenid specimens from the Uintan North American Land Mammal Age (NALMA), in the Uinta Formation, Uinta Basin, Utah. These specimens include a partial skull and several previously undescribed postcranial elements of Baena arenosa, and numerous well-preserved shells of B. arenosa and Chisternon undatum. Baenids from the Uintan NALMA (46.5-40 Ma) are critical in that they provide valuable insight into the morphology and evolution of the diverse and speciose baenid family near the end of its extensive radiation, just prior to the disappearance of this clade from the fossil record...
2017: PloS One
https://www.readbyqxmd.com/read/28673982/starch-granule-evidence-for-the-earliest-potato-use-in-north-america
#7
Lisbeth A Louderback, Bruce M Pavlik
The prehistory of wild potato use, leading to its domestication and diversification, has been well-documented in, and confined to, South America. At least 20 tuber-bearing, wild species of Solanum are known from North and Central America, yet their importance in ancient diets has never been assessed from the archaeological record. Here, we report the earliest evidence of wild potato use in North America at 10,900-10,100 calendar years (cal) B.P. in the form of well-preserved starch granules extracted from ground stone tools at North Creek Shelter, southern Utah...
July 3, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28672864/vicarious-calibration-of-suas-microbolometer-temperature-imagery-for-estimation-of-radiometric-land-surface-temperature
#8
Alfonso Torres-Rua
In recent years, the availability of lightweight microbolometer thermal cameras compatible with small unmanned aerial systems (sUAS) has allowed their use in diverse scientific and management activities that require sub-meter pixel resolution. Nevertheless, as with sensors already used in temperature remote sensing (e.g., Landsat satellites), a radiance atmospheric correction is necessary to estimate land surface temperature. This is because atmospheric conditions at any sUAS flight elevation will have an adverse impact on the image accuracy, derived calculations, and study replicability using the microbolometer technology...
June 26, 2017: Sensors
https://www.readbyqxmd.com/read/28671894/midrange-braden-subscale-scores-are-associated-with-increased-risk-for-pressure-injury-development-among-critical-care-patients
#9
Jenny Alderden, Mollie Rebecca Cummins, Ginette Alyce Pepper, JoAnne D Whitney, Yingying Zhang, Ryan Butcher, Donna Thomas
PURPOSE: The purpose of the current study was to examine the relationship between pressure injury development and the Braden Scale for Pressure Sore Risk subscale scores in a surgical intensive care unit (ICU) population and to ascertain whether the risk represented by the subscale scores is different between older and younger patients. DESIGN: Retrospective review of electronic medical records. SUBJECTS AND SETTING: The sample comprised patients admitted to the ICU at an academic medical center in the Western United States (Utah) and Level 1 trauma center between January 1, 2008 and May 1, 2013...
May 30, 2017: Journal of Wound, Ostomy, and Continence Nursing
https://www.readbyqxmd.com/read/28669242/understanding-the-experiences-of-low-income-individuals-receiving-farmers-market-incentives-in-the-united-states-a-qualitative-study
#10
Mateja R Savoie Roskos, Heidi Wengreen, Julie Gast, Heidi LeBlanc, Carrie Durward
OBJECTIVE: The objective of this study was to identify benefits and barriers to using a farmers' market (FM) incentive program among program participants. DESIGN: In qualitative semistructured interviews, participants were asked about their experiences with shopping at FM, using FM incentives, barriers to fruit and vegetable (F&V) intake, and changes in dietary intake. Interviews were recorded and transcribed. Inductive content analysis was used to code, categorize, and develop themes based on the transcriptions...
July 1, 2017: Health Promotion Practice
https://www.readbyqxmd.com/read/28663036/population-based-semen-analysis-results-and-fertility-among-patients-with-inflammatory-bowel-disease-results-from-subfertility-health-assisted-reproduction-and-the-environment-share-study
#11
Luke Martin, Sheala Mullaney, William Peche, Kathryn Peterson, Stephanie Chan, Ryan Morton, Yuan Wan, Chong Zhang, Angela P Presson, Benjamin Emery, Kenneth Aston, Timothy Jenkins, Douglas Carrell, James Hotaling
OBJECTIVE: To evaluate male fertility in Crohn's Disease (CD) and Ulcerative Colitis (UC) by examining semen analysis results and paternity from the SHARE study (subfertility health assisted reproduction and the environment), a population-based cohort of semen analysis results from Utah men. METHODS: A population-based cohort of men with CD or UC was identified using the Utah Population Database (contains person level linked demographic, genealogical, and medical record information for 85% of Utahans) from 1996-2014, and validated by clinical chart review...
June 26, 2017: Urology
https://www.readbyqxmd.com/read/28661788/abstracts-from-the-35-th-annual-national-neurotrauma-symposium-july-7-12-2017-snowbird-utah
#12
(no author information available yet)
No abstract text is available yet for this article.
July 1, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28657555/-it-feels-like-a-lot-of-extra-work-resident-attitudes-about-quality-improvement-and-implications-for-an-effective-learning-health-care-system
#13
Jorie M Butler, Katherine A Anderson, Mark A Supiano, Charlene R Weir
PURPOSE: The learning health care system promotes development and application of evidence generated within the health care system to enhance the quality of patient care. The purpose of this study was to understand resident attitudes about quality improvement (QI) in Accreditation Council for Graduate Medical Education-approved programs. METHOD: Four focus groups were conducted with 45 residents at the University of Utah School of Medicine during September and October 2014...
July 2017: Academic Medicine: Journal of the Association of American Medical Colleges
https://www.readbyqxmd.com/read/28652697/efficacy-and-safety-of-a-3-month-loteprednol-etabonate-0-5-gel-taper-for-routine-prophylaxis-after-photorefractive-keratectomy-compared-to-a-3-month-prednisolone-acetate-1-and-fluorometholone-0-1-taper
#14
Mark D Mifflin, Brent S Betts, P Adam Frederick, Jason M Feuerman, Carlton R Fenzl, Majid Moshirfar, Brian Zaugg
PURPOSE: To compare the outcome of photorefractive keratectomy (PRK) and complications in patients treated with either loteprednol etabonate 0.5% gel or prednisolone acetate 1% suspension and fluorometholone (fml) 0.1% suspension. SETTING: John A Moran Eye Center, University of Utah, Salt Lake City, UT, USA. DESIGN: Prospective, randomized, partially masked trial. METHODS: PRK was performed on 261 eyes of 132 participants...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/28650250/a-retrospective-longitudinal-claims-based-comparison-of-concomitant-diagnoses-between-individuals-with-and-without-down-syndrome
#15
Amanda M Kong, Dana Hurley, Kristin A Evans, Diana Brixner, Csilla Csoboth, Jeannie Visootsak
BACKGROUND: Individuals with Down syndrome (DS) experience various comorbidities in excess of the prevalence seen among the non-DS population. However, the extent of the excess burden of comorbidities specifically within commercially and publicly insured DS populations aged < 21 years is not currently known. OBJECTIVES: To (a) describe the most common diagnoses among individuals with DS who have either commercial or Medicaid insurance and (b) compare the prevalence of those diagnoses between DS cases and non-DS controls...
July 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28647794/an-update-on-the-risk-of-lymph-node-metastasis-for-the-follicular-variant-of-papillary-thyroid-carcinoma-with-the-new-diagnostic-paradigm
#16
Aleksandra M Sowder, Benjamin L Witt, Jason P Hunt
Previous data has shown that the risk of nodal metastases is significantly greater for classical papillary thyroid carcinoma (PTC) as compared to the follicular variant (FVPTC). Given a recent change in diagnostic paradigm and definition of the noninvasive follicular thyroid neoplasm with papillary-like nuclear features (NIFTP) we intended to investigate if there remains a significant difference in nodal involvement between classical PTC and FVPTC. A 6-year retrospective review of all cases with FVPTC in the diagnostic line from the University of Utah/ARUP Laboratories was conducted...
June 24, 2017: Head and Neck Pathology
https://www.readbyqxmd.com/read/28646404/latinas-colorectal-cancer-screening-knowledge-barriers-to-receipt-and-feasibility-of-home-based-fecal-immunochemical-testing
#17
Echo L Warner, Julia Bodson, Ryan Mooney, Djin Lai, N Jewel Samadder, Deanna Kepka
Latinas' high colorectal cancer (CRC) mortality makes them a priority population for CRC screening. CRC screening knowledge, perceived barriers, and feasibility of using the Fecal Immunochemical Test (FIT) was assessed among Latinas in Utah. Participants aged ≥50 (n = 95) were surveyed about knowledge and barriers to CRC screening. 27 participants completed a FIT and evaluation survey. Fisher's exact tests assessed sociodemographic correlates of CRC screening outcomes. Most participants were overdue for CRC screening (n = 81, 85%)...
June 23, 2017: Journal of Immigrant and Minority Health
https://www.readbyqxmd.com/read/28645235/external-validity-of-the-new-york-university-caregiver-intervention-key-caregiver-outcomes-across-multiple-demonstration-projects
#18
Elizabeth B Fauth, Mark A Jackson, Donna K Walberg, Nancy E Lee, Leisa R Easom, Gayle Alston, Angel Ramos, Kristen Felten, Asenath LaRue, Mary Mittelman
PURPOSE OF THE STUDY: The Administration on Aging funded six New York University Caregiver Intervention (NYUCI) demonstration projects, a counseling/support intervention targeting dementia caregivers and families. Three sites (Georgia, Utah, Wisconsin) pooled data to inform external validity in nonresearch settings. This study (a) assesses collective changes over time, and (b) compares outcomes across sites on caregiver burden, depressive symptoms, satisfaction with social support, family conflict, and quality of life...
June 1, 2017: Journal of Applied Gerontology: the Official Journal of the Southern Gerontological Society
https://www.readbyqxmd.com/read/28642336/the-evolving-genetic-risk-for-sporadic-als
#19
Summer B Gibson, Jonathan M Downie, Spyridoula Tsetsou, Julie E Feusier, Karla P Figueroa, Mark B Bromberg, Lynn B Jorde, Stefan M Pulst
OBJECTIVE: To estimate the genetic risk conferred by known amyotrophic lateral sclerosis (ALS)-associated genes to the pathogenesis of sporadic ALS (SALS) using variant allele frequencies combined with predicted variant pathogenicity. METHODS: Whole exome sequencing and repeat expansion PCR of C9orf72 and ATXN2 were performed on 87 patients of European ancestry with SALS seen at the University of Utah. DNA variants that change the protein coding sequence of 31 ALS-associated genes were annotated to determine which were rare and deleterious as predicted by MetaSVM...
June 22, 2017: Neurology
https://www.readbyqxmd.com/read/28640778/a-cohort-study-of-blunt-cerebrovascular-injury-screening-in-children-are-they-just-little-adults
#20
Mackenzie R Cook, Cordelie E Witt, Robert H Bonow, Eileen M Bulger, Ken F Linnau, Saman Arbabi, Bryce R H Robinson, Joseph Cuschieri
BACKGROUND: Blunt cerebrovascular injuries (BCVI) are rare with nonspecific predictors, making optimal screening critical. Radiation concerns magnify these issues in children. The Eastern Association for the Surgery of Trauma (EAST) criteria, the Utah score (US) and the Denver criteria (DC) have been advocated for pediatric BCVI screening, though direct comparison is lacking. We hypothesized that current screening guidelines inaccurately identify pediatric BCVI. METHODS: This was a retrospective cohort study of pediatric trauma patients treated from 2005-2015 with radiographically confirmed BCVI...
June 20, 2017: Journal of Trauma and Acute Care Surgery
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