keyword
MENU ▼
Read by QxMD icon Read
search

Rotman

keyword
https://www.readbyqxmd.com/read/28579125/prognostic-implications-of-left-ventricular-global-longitudinal-strain-in-predialysis-and-dialysis-patients
#1
Liselotte C R Hensen, Kathleen Goossens, Victoria Delgado, Joris I Rotmans, J Wouter Jukema, Jeroen J Bax
Chronic kidney disease (CKD) is a worldwide growing epidemic associated with an increased risk of cardiovascular morbidity and mortality. Left ventricular (LV) global longitudinal strain (GLS) is a measure of LV systolic function associated with prognosis in the general population. However, little is known about the association between LV GLS and survival in patients with CKD. The aim of the present study was to investigate the prognostic implications of LV GLS in predialysis and dialysis patients specifically...
May 11, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28541443/the-impact-of-multidisciplinary-care-on-early-morbidity-and-mortality-after-heart-transplantation
#2
Marie Schmidhauser, Julien Regamey, Nathalie Pilon, Manuel Pascual, Sam Rotman, Carlo Banfi, René Prêtre, Philippe Meyer, Jean-Philippe Antonietti, Roger Hullin
OBJECTIVES: The impact of multidisciplinary care on outcome after heart transplantation (HTx) remains unclear. METHODS: This retrospective study investigates the impact of multidisciplinary care on the primary end point 1-year all-cause mortality (ACM) and the secondary end point mean acute cellular rejection (ACR) grade within the first postoperative year. RESULTS: This study includes a total 140 HTx recipients (median age: 53.5 years; males: 80%; donor/recipient gender mismatch: 38...
May 24, 2017: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/28530076/-osteoporosis-and-diabetes-in-which-way-are-they-related
#3
REVIEW
Osnat Tell-Lebanon, Pnina Rotman-Pikielny
Diabetes and osteoporosis are common diseases with growing prevalence in the aging population. Many recent studies have reported an association between diabetes mellitus and an increased osteoporotic fracture rate. Compared to control subjects, decreased bone mineral density has been observed in patients with type 1 diabetes mellitus, while those with type 2 diabetes display a unique skeletal phenotype of increased bone mineral density, but impaired architectural structure and mineral properties. Accumulation of advanced glycation end products changes collagen structure and suppression of bone turnover causes impairment of repair and adaptation mechanisms...
November 2016: Harefuah
https://www.readbyqxmd.com/read/28470683/how-healthy-are-the-healthy-volunteers-penetrance-of-nafld-in-the-biomedical-research-volunteer-pool
#4
Varun Takyar, Anand Nath, Andrea Beri, Ahmed M Gharib, Yaron Rotman
INTRODUCTION: Healthy volunteers are crucial for biomedical research. Inadvertent inclusion of subjects with non-alcoholic fatty liver disease (NAFLD) as controls can compromise study validity and subject safety. Given the rising prevalence of NAFLD in the general population, we sought to identify its prevalence and potential impact in volunteers for clinical trials. METHODS: Cross-sectional study of subjects with "Healthy Volunteer" diagnosis between 2011-2015 and no known liver disease...
May 3, 2017: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/28466261/endoscopic-localization-of-colon-cancer-is-frequently-inaccurate
#5
Jennifer Nayor, Stephen R Rotman, Walter W Chan, Joel E Goldberg, John R Saltzman
BACKGROUND: Colonoscopic location of a tumor can influence both the surgical procedure choice and overall treatment strategy. AIMS: To determine the accuracy of colonoscopy in determining the location of colon cancer compared to surgical localization and to elucidate factors that predict discordant colon cancer localization. METHODS: We conducted a retrospective cross-sectional study of colon cancers diagnosed on colonoscopy at two academic tertiary-care hospitals and two affiliated community hospitals from 2012 to 2014...
May 2, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28405605/three-dimensional-self-navigated-t2-mapping-for-the-detection-of-acute-cellular-rejection-after-orthotopic-heart-transplantation
#6
Ruud B van Heeswijk, Davide Piccini, Piergiorgio Tozzi, Samuel Rotman, Philippe Meyer, Juerg Schwitter, Matthias Stuber, Roger Hullin
BACKGROUND: T2 mapping is a magnetic resonance imaging technique measuring T2 relaxation time, which increases with the myocardial tissue water content. Myocardial edema is a component of acute cellular rejection (ACR) after heart transplantation. This pilot study compares in heart transplantation recipients a novel high resolution 3-dimensional (3D) T2-mapping technique with standard 2-dimensional (2D) T2-mapping for ACR detection. METHODS: Consecutive asymptomatic patients (n = 26) underwent both 3D T2 mapping and reference 2D T2 mapping magnetic resonance imaging on the day of endomyocardial biopsy (EMB)...
April 2017: Transplantation Direct
https://www.readbyqxmd.com/read/28375518/generation-and-validation-of-the-ikp1289-metabolic-model-for-klebsiella-pneumoniae-kppr1
#7
Christopher S Henry, Ella Rotman, Wyndham W Lathem, Keith E J Tyo, Alan R Hauser, Mark J Mandel
Klebsiella pneumoniae has a reputation for causing a wide range of infectious conditions, with numerous highly virulent and antibiotic-resistant strains. Metabolic models have the potential to provide insights into the growth behavior, nutrient requirements, essential genes, and candidate drug targets in these strains. Here we develop a metabolic model for KPPR1, a highly virulent strain of K. pneumoniae. We apply a combination of Biolog phenotype data and fitness data to validate and refine our KPPR1 model...
February 15, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28370243/sonographic-evaluation-of-renovascular-hypertension-in-the-pediatric-population-state-of-the-art
#8
REVIEW
Anat Ilivitzki, Luda Glozman, Rebeca Lopez Alfonso, Amos Ofer, Nira Beck Razi, Mika Rotman Shapira
Hypertension in children affects 2-5% of the pediatric population. Identifying secondary causes of hypertension is crucial, as some of these entities may be treatable. Renovascular hypertension accounts for 5-10% of the secondary causes of hypertension in children and is mainly related to fibromuscular dysplasia and neurofibromatosis type 1. Ultrasonographic evaluation of the kidneys, including Doppler interrogation, is the recommended primary screening tool. A comprehensive study of the upper abdomen and retroperitoneum allows for identification of additional underlying etiologies...
March 28, 2017: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/28367219/alpha-1-antitrypsin-deficiency-presenting-with-mpo-anca-associated-vasculitis-and-aortic-dissection
#9
Bram M Voorzaat, Jan van Schaik, Stijn L P Crobach, Catharina S P van Rijswijk, Joris I Rotmans
The combination of alpha-1 antitrypsin (AAT) deficiency, ANCA-vasculitis, and aortic aneurysm has been rarely described in literature. We report an eventually fatal case in a 70-year-old patient who initially presented with giant cell arteritis and ANCA associated glomerulonephritis. Several years later, he presented with aortic dissection due to large vessel vasculitis, raising the suspicion of AAT deficiency, as two first-line relatives had chronic obstructive pulmonary disease, while they never smoked. This diagnosis was confirmed by AAT electrophoresis and immunohistochemistry on a temporal artery biopsy...
2017: Case Reports in Medicine
https://www.readbyqxmd.com/read/28355579/stability-of-bk-polyomavirus-igg-seroreactivity-and-its-correlation-with-preceding-viremia
#10
Herman F Wunderink, Els van der Meijden, Caroline S van der Blij-de Brouwer, Hans L Zaaijer, Aloys C M Kroes, Erik W van Zwet, Joris I Rotmans, Mariet C W Feltkamp
BACKGROUND: Recently we showed that the level of BK polyomavirus (BKPyV) IgG seroreactivity in kidney donors predicted viremia and BKPyV-associated nephropathy in kidney transplant recipients (KTRs). This observation could be explained by assuming a direct association between BKPyV seroreactivity and the amount of persistent infectious virus in the renal allograft. OBJECTIVES: Since the renal BKPyV reservoir is probably sowed by viremia during primary BKPyV infection, we systematically analysed the dynamics of BKPyV IgG seroreactivity in relation to preceding BKPyV viremia in KTRs and healthy individuals...
March 19, 2017: Journal of Clinical Virology: the Official Publication of the Pan American Society for Clinical Virology
https://www.readbyqxmd.com/read/28324856/quantification-of-groundwater-recharge-in-urban-environments
#11
Isabel Tubau, Enric Vázquez-Suñé, Jesús Carrera, Cristina Valhondo, Rotman Criollo
Groundwater management in urban areas requires a detailed knowledge of the hydrogeological system as well as the adequate tools for predicting the amount of groundwater and water quality evolution. In that context, a key difference between urban and natural areas lies in recharge evaluation. A large number of studies have been published since the 1990s that evaluate recharge in urban areas, with no specific methodology. Most of these methods show that there are generally higher rates of recharge in urban settings than in natural settings...
March 18, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28297049/improvement-of-radiocephalic-fistula-maturation-rationale-and-design-of-the-liposomal-prednisolone-to-improve-hemodialysis-fistula-maturation-lipmat-study-a-randomized-controlled-trial
#12
Bram M Voorzaat, Jan van Schaik, Koen E A van der Bogt, Liffert Vogt, Laurens Huisman, Bas A Th F Gabreëls, Irene M van der Meer, Randolph G S van Eps, Daniël Eefting, Marcel C Weijmer, Han O Groeneveld, Roos C van Nieuwenhuizen, Henk Boom, Cornelis A Verburgh, Karien van der Putten, Joris I Rotmans
BACKGROUND: Non-maturation is a frequent complication of radiocephalic arteriovenous fistulas (RCAVF). In an animal model, liposomal prednisolone improved maturation of experimental fistulas. The Liposomal Prednisolone to Improve Hemodialysis Fistula Maturation (LIPMAT) study investigates if liposomal prednisolone improves RCAVF maturation. METHODS AND RESULTS: The LIPMAT study is an investigator-initiated, multicenter, double-blinded, placebo-controlled randomized controlled trial with 1:1 randomization to liposomal prednisolone or placebo...
March 6, 2017: Journal of Vascular Access
https://www.readbyqxmd.com/read/28277277/immunoregulation-of-dendritic-cell-subsets-by-inhibitory-receptors-in-urothelial-cancer
#13
Mathieu F Chevalier, Perrine Bohner, Claire Pieraerts, Benoit Lhermitte, Jolanta Gourmaud, Antoine Nobile, Samuel Rotman, Valerie Cesson, Virginie Martin, Anne-Sophie Legris, Florence Dartiguenave, Dalila Gharbi, Laurence De Leval, Daniel E Speiser, Denise Nardelli-Haefliger, Patrice Jichlinski, Laurent Derré
Blockade of inhibitory receptors (IRs) overexpressed by T cells can activate antitumor immune responses, resulting in the most promising therapeutic approaches, particularly in bladder cancer, currently able to extend patient survival. Thanks to their ability to cross-present antigens to T cells, dendritic cells (DCs) are an immune cell population that plays a central role in the generation of effective antitumor T-cell responses. While IR function and expression have been investigated in T cells, very few data are available for DCs...
June 2017: European Urology
https://www.readbyqxmd.com/read/28274997/what-if-prometheus-had-steatosis-potential-use-of-fgf19-to-promote-regeneration-of-the-fatty-liver
#14
Philip M Brown, Yaron Rotman
No abstract text is available yet for this article.
March 8, 2017: Gut
https://www.readbyqxmd.com/read/28253835/abdominal-aortic-calcification-on-a-plain-x-ray-and-the-relation-with-significant-coronary-artery-disease-in-asymptomatic-chronic-dialysis-patients
#15
M K de Bie, M S Buiten, J I Rotmans, M Hogenbirk, M J Schalij, T J Rabelink, J W Jukema
BACKGROUND: Coronary artery disease (CAD) is common in asymptomatic chronic dialysis patients and plays an important role in their poor survival. Early identification of these high-risk patients could improve treatment and reduce mortality. Abdominal aortic calcification (AAC) has previously been associated with CAD in autopsy studies. Since the AAC can be quantified easily using a lateral lumbar X-ray we hypothesized that the extent of AAC as assessed on a lateral lumbar X-ray might be predictive of the presence of significant CAD in dialysis patients...
March 2, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28231284/correction-tracking-career-outcomes-for-postdoctoral-scholars-a-call-to-action
#16
Elizabeth A Silva, Christine Des Jarlais, Bill Lindstaedt, Erik Rotman, Elizabeth S Watkins
[This corrects the article DOI: 10.1371/journal.pbio.1002458.].
February 2017: PLoS Biology
https://www.readbyqxmd.com/read/28205013/utilizing-the-foreign-body-response-to-grow-tissue-engineered-blood-vessels-in-vivo
#17
Wouter J Geelhoed, Lorenzo Moroni, Joris I Rotmans
It is well known that the number of patients requiring a vascular grafts for use as vessel replacement in cardiovascular diseases, or as vascular access site for hemodialysis is ever increasing. The development of tissue engineered blood vessels (TEBV's) is a promising method to meet this increasing demand vascular grafts, without having to rely on poorly performing synthetic options such as polytetrafluoroethylene (PTFE) or Dacron. The generation of in vivo TEBV's involves utilizing the host reaction to an implanted biomaterial for the generation of completely autologous tissues...
April 2017: Journal of Cardiovascular Translational Research
https://www.readbyqxmd.com/read/28152575/liver-fat-accumulation-as-a-barometer-of-insulin-responsiveness-again-points-to-adipose-tissue-as-the-culprit
#18
EDITORIAL
Yaron Rotman, Brent A Neuschwander-Tetri
No abstract text is available yet for this article.
April 2017: Hepatology: Official Journal of the American Association for the Study of Liver Diseases
https://www.readbyqxmd.com/read/28131618/taliglucerase-alfa-in-gaucher-disease-description-of-a-brazilian-experience
#19
R Cravo, V Rotman, P M N Oliveira, H G T Defendi, D A Conceição, J R Xavier, R Chertkoff, T G Noronha, M L S Maia
We evaluated retrospectively, efficacy and safety of taliglucerase alfa for Gaucher disease in a Brazilian population. Thirteen patients were included for efficacy analysis only one of them naïve to enzyme replacement therapy. All the parameters evaluated remained stable throughout treatment (mean duration 3,5years). Only three patients (out of 35) had to discontinue treatment due to a serious adverse event. In conclusion, treatment with taliglucerase alfa was found to be safe and efficient.
January 16, 2017: Blood Cells, Molecules & Diseases
https://www.readbyqxmd.com/read/28116653/classical-and-additional-antiphospholipid-antibodies-in-blood-samples-of-ischemic-stroke-patients-and-healthy-controls
#20
Narin-Nard Carmel-Neiderman, David Tanne, Idan Goren, Pnina Rotman-Pikielny, Yair Levy
Classical antiphospholipid antibodies (aPLa) are found in 6-25% of blood samples from stroke patients. The frequency of novel aPLa antibodies in blood samples of CVA patients is not known. Enzyme-linked immunosorbent assays (ELISA) were performed on blood samples from 209 CVA patients (170 samples were obtained during the acute phase and 39 samples were from patients with complete carotid stenosis) and compared to 54 healthy controls. Subjects were tested for the presence of the classical aPL antibodies anticardiolipin (aCL) and anti-beta2-glycoprotein (aβ2gI), in addition to antiphosphatidylethanolamine (aPE), anti-phosphatidylserine (aPS), and Annexin V...
January 23, 2017: Immunologic Research
keyword
keyword
76097
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"