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https://www.readbyqxmd.com/read/28642183/giant-bi-compartmental-cystic-tentorial-schwannoma-mimicking-a-meningioma
#1
Amandeep Kumar, Manmohan Singh, M C Sharma, P S Chandra, Bhawani S Sharma, Ashok K Mahapatra
BACKGROUND: Intracranial schwannomas most commonly arise from vestibulo-cochlear nerve and less frequently from trigeminal, facial and hypoglossal nerves. However, intracranial schwannomas unrelated to cranial nerves (ISUNs) are very rare and only ∼ 50 such cases have been reported in literature. Amongst these, tentorial schwannomas are even rarer and only 13 cases have been reported till date. We present one such rare case of giant tentorial schwannoma (TS). CASE DESCRIPTION: A 21 year old male patient presented to us with complaints of generalised headache and dizziness for past 6 months and worsening of symptoms for past 2 months...
June 19, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28633960/effect-of-stimulus-level-on-the-temporal-response-properties-of-the-auditory-nerve-in-cochlear-implants
#2
Michelle L Hughes, Sarah A Laurello
Electrically evoked compound action potentials (ECAPs) have been used to examine temporal response patterns of the auditory nerve in cochlear implant (CI) recipients. ECAP responses to individual pulses in a pulse train vary across stimulation rates for individual CI users. For very slow rates, auditory neurons have ample time to discharge, recover, and respond to each pulse in the train. As the pulse rate increases, an alternating ECAP-amplitude pattern occurs. As the stimulation rate increases further, the alternating pattern eventually ceases and the overall ECAP amplitudes are diminished, yielding a relatively stochastic state that presumably reflects a combination of adaptation, desynchronization, and facilitation across fibers...
June 13, 2017: Hearing Research
https://www.readbyqxmd.com/read/28631161/the-role-of-eabr-with-intracochlear-test-electrode-in-decision-making-between-cochlear-and-brainstem-implants-preliminary-results
#3
Betul Cicek Cinar, Mehmet Yarali, Gamze Atay, Munir Demir Bajin, Gonca Sennaroglu, Levent Sennaroglu
The objective of the study was to discuss the findings of intraoperative electrically evoked auditory brainstem response (eABR) test results with a recently designed intracochlear test electrode (ITE) in terms of their relation to decisions of cochlear or auditory brainstem implantation. This clinical study was conducted in Hacettepe University, Department of Otolaryngology, Head and Neck Surgery and Department of Audiology. Subjects were selected from inner ear malformation (IEM) database. Eleven subjects with profound sensorineural hearing loss were included in the current study with age range from 1 year 3 months to 4 years 3 months for children with prelingual hearing loss...
June 19, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28628917/anatomical-characteristics-of-facial-nerve-and-cochlea-interaction
#4
Nadine Schart-Morén, Sune Larsson, Helge Rask-Andersen, Hao Li
OBJECTIVE: The aim was to study the relationship between the labyrinthine portion (LP) of the facial canal and the cochlea in human inner ear molds and temporal bones using micro-CT and 3D rendering. A reduced cochlea-facial distance may spread electric currents from the cochlear implant to the LP and cause facial nerve stimulation. Influencing factors may be the topographic anatomy and otic capsule properties. METHODS: An archival collection of human temporal bones underwent micro-CT and 3D reconstruction...
June 20, 2017: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/28625417/modeled-auditory-nerve-responses-to-amplitude-modulated-cochlear-implant-stimulation
#5
M J van Gendt, J J Briaire, R K Kalkman, J H M Frijns
Cochlear implants encode speech information by stimulating the auditory nerve with amplitude-modulated pulse trains. A computer model of the auditory nerve's response to electrical stimulation can be used to evaluate different approaches to improving CI patients' perception. In this paper a computationally efficient stochastic and adaptive auditory nerve model was used to investigate full nerve responses to amplitude-modulated electrical pulse trains. The model was validated for nerve responses to AM pulse trains via comparison with animal data...
May 19, 2017: Hearing Research
https://www.readbyqxmd.com/read/28620284/electrophysiological-measurements-of-peripheral-vestibular-function-a-review-of-electrovestibulography
#6
REVIEW
Daniel J Brown, Christopher J Pastras, Ian S Curthoys
Electrocochleography (EcochG), incorporating the Cochlear Microphonic (CM), the Summating Potential (SP), and the cochlear Compound Action Potential (CAP), has been used to study cochlear function in humans and experimental animals since the 1930s, providing a simple objective tool to assess both hair cell (HC) and nerve sensitivity. The vestibular equivalent of ECochG, termed here Electrovestibulography (EVestG), incorporates responses of the vestibular HCs and nerve. Few research groups have utilized EVestG to study vestibular function...
2017: Frontiers in Systems Neuroscience
https://www.readbyqxmd.com/read/28618834/psychophysical-and-modeling-approaches-towards-determining-the-cochlear-phase-response-based-on-interaural-time-differences
#7
Hisaaki Tabuchi, Bernhard Laback
The cochlear phase response is often estimated by measuring masking of a tonal target by harmonic complexes with various phase curvatures. Maskers yielding most modulated internal envelope representations after passing the cochlear filter are thought to produce minimum masking, with fast-acting cochlear compression as the main contributor to that effect. Thus, in hearing-impaired (HI) listeners, reduced cochlear compression hampers estimation of the phase response using the masking method. This study proposes an alternative approach, based on the effect of the envelope modulation strength on the sensitivity to interaural time differences (ITDs)...
June 2017: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/28602150/translabyrinthine-vestibular-schwannoma-resection-with-simultaneous-cochlear-implantation
#8
Austin N DeHart, William C Broaddus, Daniel H Coelho
OBJECTIVES: (1) Report a rare case of translabyrinthine resection of a sporadic vestibular schwannoma (VS) and concurrent cochlear implantation (CI). (2) Discuss pre-, intra-, and post-operative considerations in this unique patient population. (3) Describe surgical and audiologic outcomes reported in this population. METHODS: Case report and review of the literature. PubMed search 'Cochlear Implantation'[Mesh] AND ('Neuroma, Acoustic'[Mesh] OR 'VESTIBULAR SCHWANNOMA'[All Fields] OR 'SCHWANNOMA'[All Fields]) limited to humans and English language...
June 12, 2017: Cochlear Implants International
https://www.readbyqxmd.com/read/28600233/effect-of-tissue-heterogeneity-on-the-transmembrane-potential-of-type-1-spiral-ganglion-neurons-a-simulation-study
#9
Kiran Sriperumbudur, Hans Wilhelm Pau, Ursula van Rienen
Electric stimulation of the auditory nerve by cochlear implants has been a successful clinical intervention to treat the sensory neural deafness. In this pathological condition of the cochlea, type-1 spiral ganglion neurons in Rosenthal's canal play a vital role in the action potential initiation. Various morphological studies of the human temporal bones suggest that the spiral ganglion neurons are surrounded by heterogeneous structures formed by a variety of cells and tissues. However, the existing simulation models have not considered the tissue heterogeneity in the Rosenthal's canal while studying the electric field interaction with spiral ganglion neurons...
June 5, 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28597033/topography-of-neurovascular-structures-in-relation-to-round-window-and-how-it-relates-to-cochlear-implantation
#10
Anjali Singla, Tulika Gupta, Daisy Sahni, Ashok Kumar Gupta, Anjali Aggarwal
PURPOSE: The purpose of this investigation was to evaluate the distances and angles on basal turn of cochlea in relation to round window at which the jugular bulb, internal carotid artery and facial nerve are at maximal risk and their implications in cochlear implantation (CI). METHODS: Fifty-four cadaveric temporal bones were microdissected to expose the basal turn of cochlea, the carotid canal, the facial canal and the jugular fossa. The points were marked on the basal turn of cochlea, where there was minimum distance of basal turn of cochlea from the roof of the jugular fossa (point a), carotid canal (point b) and facial canal (point c)...
June 8, 2017: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/28584970/morphometric-evaluation-of-facial-and-vestibulocochlear-nerves-using-magnetic-resonance-imaging-comparison-of-meni%C3%A3-re-s-disease-ears-with-normal-hearing-ears
#11
Annika Henneberger, Birgit Ertl-Wagner, Maximilian Reiser, Robert Gürkov, Wilhelm Flatz
Loss of neural structures (such as hair cells or neurones within the spiral ganglion) has been proposed to be involved in Menière's disease (MD) (Spoendlin et al. Acta oto-laryngologica Supplementum 499:1-21, 1; Merchant et al. Eur Arch Oto-Rhino-Laryngol Off J Eur Feder Oto-Rhino-Laryngol Soc (EUFOS) Affil German Soc Oto-Rhino-Laryngol Head Neck Surg 252(2):63-75, 2; Tsuji et al. Ann Otol Rhinol Laryngol Suppl 81:26-31, 3; Kariya, Otol Neurotol Off Publ Am Otol Soc Am Neurotol Soc Eur Acad Otol Neurotol 28(8):1063-1068, 4; Megerian Laryngoscope 115(9):1525-1535, 5) but this has yet to be confirmed...
June 5, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28576729/afferent-synaptogenesis-between-ectopic-hair-cell-like-cells-and-neurites-of-spiral-ganglion-induced-by-atoh1-in-mammals-in-vitro
#12
Wen-Wei Luo, Rui Ma, Xiang Cheng, Xiao-Yu Yang, Zhao Han, Dong-Dong Ren, Ping Chen, Fang-Lu Chi, Juan-Mei Yang
Newly formed ectopic hair-cell-like cells (EHCLCs) induced by overexpression of atonal homolog 1 (Atoh1) in vitro were found to possess features of endogenous hair cells (HCs) in previous reports and in the present study. However, limited information is available regarding whether EHCLCs and native spiral ganglion neurons (SGNs) form afferent synapses, which are important for the restoration of hearing. In the current study, we focused on the afferent synaptogenesis between EHCLCs and SGN-derived dendrites...
May 31, 2017: Neuroscience
https://www.readbyqxmd.com/read/28566097/bony-cochlear-nerve-canal-and-internal-auditory-canal-measures-predict-cochlear-nerve-status
#13
E Tahir, M D Bajin, G Atay, B Ö Mocan, L Sennaroğlu
OBJECTIVES: The bony cochlear nerve canal is the space between the fundus of the internal auditory canal and the base of the cochlear modiolus that carries cochlear nerve fibres. This study aimed to determine the distribution of bony labyrinth anomalies and cochlear nerve anomalies in patients with bony cochlear nerve canal and internal auditory canal atresia and stenosis, and then to compare the diameter of the bony cochlear nerve canal and internal auditory canal with cochlear nerve status...
June 1, 2017: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/28553221/tumors-presenting-as-multiple-cranial-nerve-palsies
#14
Kishore Kumar, Rafeeq Ahmed, Bharat Bajantri, Amandeep Singh, Hafsa Abbas, Eddy Dejesus, Rana Raheel Khan, Masooma Niazi, Sridhar Chilimuri
Cranial nerve palsy could be one of the presenting features of underlying benign or malignant tumors of the head and neck. The tumor can involve the cranial nerves by local compression, direct infiltration or by paraneoplastic process. Cranial nerve involvement depends on the anatomical course of the cranial nerve and the site of the tumor. Patients may present with single or multiple cranial nerve palsies. Multiple cranial nerve involvement could be sequential or discrete, unilateral or bilateral, painless or painful...
January 2017: Case Reports in Neurology
https://www.readbyqxmd.com/read/28538522/frequency-specificity-and-left-ear-advantage-of-medial-olivocochlear-efferent-modulation-a-study-based-on-stimulus-frequency-otoacoustic-emission
#15
Dongjia Xing, Qin Gong
The medial olivocochlear (MOC) bundle is an auditory nucleus that projects efferent nerve fibers to the outer hair cells (OHCs) for synaptic innervation. The aim of the present study was to investigate the possible existence of frequency and ear specificity in MOC efferent modulation, as well as how MOC activation influences cochlear tuning. Stimulus frequency otoacoustic emissions (SFOAEs) were used to study MOC efferent modulation. Therefore, the current experiment was designed to compare the degree of SFOAE suppression in the both ears of 20 individuals at 1, 2, 4, and 8 kHz...
May 19, 2017: Neuroreport
https://www.readbyqxmd.com/read/28538470/progression-of-unilateral-hearing-loss-in-children-with-and-without-ipsilateral-cochlear-nerve-canal-stenosis-a-hazard-analysis
#16
Patricia L Purcell, Justin R Shinn, Scott S Coggeshall, Grace Phillips, Angelisa Paladin, Kathleen C Y Sie, David L Horn
OBJECTIVE: To investigate the risk of hearing loss progression in each ear among children with unilateral hearing loss associated with ipsilateral bony cochlear nerve canal (BCNC) stenosis. SETTING: Tertiary pediatric referral center. PATIENTS: Children diagnosed with unilateral hearing loss who had undergone temporal bone computed tomography imaging and had at least 6 months of follow-up audiometric testing were identified from a prospective audiological database...
July 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28534045/compound-heterozygous-mutations-in-masp1-in-a-deaf-child-with-absent-cochlear-nerves
#17
Elina Kari, Isabelle Schrauwen, Lorida Llaci, Laurel M Fisher, John L Go, Marcus Naymik, James A Knowles, Matthew J Huentelman, Rick A Friedman
No abstract text is available yet for this article.
June 2017: Neurology. Genetics
https://www.readbyqxmd.com/read/28530663/a-cerebellum-like-circuit-in-the-auditory-system-cancels-responses-to-self-generated-sounds
#18
Shobhit Singla, Conor Dempsey, Richard Warren, Armen G Enikolopov, Nathaniel B Sawtell
The dorsal cochlear nucleus (DCN) integrates auditory nerve input with a diverse array of sensory and motor signals processed in circuitry similar to that of the cerebellum. Yet how the DCN contributes to early auditory processing has been a longstanding puzzle. Using electrophysiological recordings in mice during licking behavior, we show that DCN neurons are largely unaffected by self-generated sounds while remaining sensitive to external acoustic stimuli. Recordings in deafened mice, together with neural activity manipulations, indicate that self-generated sounds are cancelled by non-auditory signals conveyed by mossy fibers...
May 22, 2017: Nature Neuroscience
https://www.readbyqxmd.com/read/28523516/pre-operative-screening-and-manual-drilling-strategies-to-reduce-the-risk-of-thermal-injury-during-minimally-invasive-cochlear-implantation-surgery
#19
Neal P Dillon, Loris Fichera, Kyle Kesler, M Geraldine Zuniga, Jason E Mitchell, Robert J Webster, Robert F Labadie
This article presents the development and experimental validation of a methodology to reduce the risk of thermal injury to the facial nerve during minimally invasive cochlear implantation surgery. The first step in this methodology is a pre-operative screening process, in which medical imaging is used to identify those patients that present a significant risk of developing high temperatures at the facial nerve during the drilling phase of the procedure. Such a risk is calculated based on the density of the bone along the drilling path and the thermal conductance between the drilling path and the nerve, and provides a criterion to exclude high-risk patients from receiving the minimally invasive procedure...
May 18, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28516364/preserving-normal-facial-nerve-function-and-improving-hearing-outcome-in-large-vestibular-schwannomas-with-a-combined-approach-planned-subtotal-resection-followed-by-gamma-knife-radiosurgery
#20
Roy Thomas Daniel, Constantin Tuleasca, Mercy George, Etienne Pralong, Luis Schiappacasse, Michele Zeverino, Raphael Maire, Marc Levivier
OBJECTIVE: To perform planned subtotal resection followed by gamma knife surgery (GKRS) in a series of patients with large vestibular schwannoma (VS), aiming at an optimal functional outcome for facial and cochlear nerves. METHODS: Patient characteristics, surgical and dosimetric features, and outcome were collected prospectively at the time of treatment and during the follow-up. RESULTS: A consecutive series of 32 patients was treated between July 2010 and June 2016...
July 2017: Acta Neurochirurgica
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