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https://www.readbyqxmd.com/read/27910733/a-comparative-morphologic-and-morphometric-study-about-geniculate-ganglion-development-in-man-and-in-rat
#1
Ana Sánchez-Del-Rey, José Maria Sánchez-Fernández, Arantza Ibargutxi, Agustin Martinez-Ibargüen, Francisco Santaolalla
CONCLUSIONS: Human-rat geniculate ganglion (GG) have multiple origins: (1) An initial proximity (20 μm) to the endocranial foramen of the IAM, suggests neural crest induction; and (2) The influence of epibranchial placodes: the tensor tympani muscle (TTM) and the otic apical coil. OBJECTIVES: This study was undertaken to determine the comparative development of human-rat GG. MATERIALS AND METHODS: A light microscopic study of the GG in human material obtained from spontaneous abortions at 9, 13, 14, 17, 18, and 30 weeks, and one neonate was done...
December 2, 2016: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/27904821/auditory-brainstem-response-and-late-latency-response-in-individuals-with-tinnitus-having-normal-hearing
#2
Sreeraj Konadath, Puttabasappa Manjula
Tinnitus is a commonly encountered complaint in routine audiology practice. The pathophysiology and exact generation site of tinnitus is not precisely established. Auditory brainstem response (ABR) and late latency response (LLR) findings in individuals with tinnitus show mixed results in the literature. Majority of studies have focused on individuals having tinnitus with peripheral hearing loss. The present study explores ABR and LLR characteristics among tinnitus patients with normal audiometric presentation; with no direct indication of any cochlear lesion...
November 2016: Intractable & Rare Diseases Research
https://www.readbyqxmd.com/read/27903183/stereotactic-radiosurgery-for-vestibular-schwannomas-average-10-year-follow-up-results-focusing-on-long-term-hearing-preservation
#3
Shinya Watanabe, Masaaki Yamamoto, Takuya Kawabe, Takao Koiso, Tetsuya Yamamoto, Akira Matsumura, Hidetoshi Kasuya
OBJECTIVE The aim of this study was to reappraise long-term treatment outcomes of stereotactic radiosurgery (SRS) for vestibular schwannomas (VSs). The authors used a database that included patients who underwent SRS with a unique dose-planning technique, i.e., partial tumor coverage designed to avoid excess irradiation of the facial and cochlear nerves, focusing on tumor control and hearing preservation. Clinical factors associated with post-SRS tumor control and long-term hearing preservation were also analyzed...
December 2016: Journal of Neurosurgery
https://www.readbyqxmd.com/read/27900916/electrically-evoked-compound-action-potentials-are-different-depending-on-the-site-of-cochlear-stimulation
#4
Paul van de Heyning, Santiago L Arauz, Marcus Atlas, Wolf-Dieter Baumgartner, Marco Caversaccio, Ronel Chester-Browne, Patricia Estienne, Javier Gavilan, Benoit Godey, Wolfgang Gstöttner, Demin Han, Rudolph Hagen, Martin Kompis, Vlad Kuzovkov, Luis Lassaletta, Franc Lefevre, Yongxin Li, Joachim Müller, Lorne Parnes, Andrea Kleine Punte, Christopher Raine, Gunesh Rajan, Adriana Rivas, José Antonio Rivas, Nicola Royle, Georg Sprinzl, Kurt Stephan, Adam Walkowiak, Yuri Yanov, Kim Zimmermann, Patrick Zorowka, Henryk Skarzynski
One of the many parameters that can affect cochlear implant (CI) users' performance is the site of presentation of electrical stimulation, from the CI, to the auditory nerve. Evoked compound action potential (ECAP) measurements are commonly used to verify nerve function by stimulating one electrode contact in the cochlea and recording the resulting action potentials on the other contacts of the electrode array. The present study aimed to determine if the ECAP amplitude differs between the apical, middle, and basal region of the cochlea, if double peak potentials were more likely in the apex than the basal region of the cochlea, and if there were differences in the ECAP threshold and recovery function across the cochlea...
November 30, 2016: Cochlear Implants International
https://www.readbyqxmd.com/read/27898605/initial-results-of-a-safety-and-feasibility-study-of-auditory-brainstem-implantation-in-congenitally-deaf-children
#5
Eric P Wilkinson, Laurie S Eisenberg, Mark D Krieger, Marc S Schwartz, Margaret Winter, Jamie L Glater, Amy S Martinez, Laurel M Fisher, Robert V Shannon
OBJECTIVE: To determine the safety and feasibility of the auditory brainstem implant (ABI) in congenitally deaf children with cochlear aplasia and/or cochlear nerve deficiency. STUDY DESIGN: Phase I feasibility clinical trial of surgery in 10 children, ages 2 to 5 years, over a 3-year period. SETTING: Tertiary children's hospital and university-based pediatric speech/language/hearing center. INTERVENTION(S): ABI implantation and postsurgical programming...
November 24, 2016: Otology & Neurotology
https://www.readbyqxmd.com/read/27897128/defining-the-limits-of-endoscopic-access-to-internal-auditory-canal
#6
Adam Master, Mickie Hamiter, Maura Cosetti
OBJECTIVE: To quantify surgical access to the internal auditory canal (IAC) using an exclusively endoscopic transcanal approach (EETA) and investigate surgically relevant relationships with neurovascular and osseous landmarks of the temporal bone. MATERIALS AND METHODS: Anatomical dissection of two paired temporal bones and 15 unpaired temporal bones was performed using an exclusively endoscopic approach to IAC. The dissection proceeded until the cerebellopontine angle (CPA) could be accessed...
November 28, 2016: Journal of International Advanced Otology
https://www.readbyqxmd.com/read/27891421/imaging-modality-of-choice-for-pre-operative-cochlear-imaging-hrct-vs-mri-temporal-bone
#7
Poornima Digge, Rajendra N Solanki, Dipali C Shah, Rajesh Vishwakarma, Sandeep Kumar
INTRODUCTION: Congenital inner ear malformations occur as a result of the arrest or aberrance of inner ear development due to the heredity, gene mutation or other factors. Ever since the availability of cochlear implants, pre-operative evaluation by imaging of temporal bone has gained much attention. Precise selection of the candidate for cochlear implant dependent on preoperative radiological investigations. Only CT (Computed Tomography) and MRI (Magnetic Resonance Imaging) can provide a better picture of anatomy and pathology...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27889918/inner-ear-labyrinth-anatomy-of-monotremes-and-implications-for-mammalian-inner-ear-evolution
#8
Julia A Schultz, Ulrich Zeller, Zhe-Xi Luo
The monophyletic clade Monotremata branches early from the rest of the mammalian crown group in the Jurassic and members of this clade retain many ancestral mammalian traits. Thus, accurate and detailed anatomical descriptions of this group can offer unique insight into the early evolutionary history of Mammalia. In this study, we examine the inner ear anatomy of two extant monotremes, Ornithorhynchus anatinus and Tachyglossus aculeatus, with the primary goals of elucidating the ancestral mammalian ear morphology and resolving inconsistencies found within previous descriptive literature...
November 27, 2016: Journal of Morphology
https://www.readbyqxmd.com/read/27881784/low-somatic-sodium-conductance-enhances-action-potential-precision-in-time-coding-auditory-neurons
#9
Yang Yang, Bina Ramamurthy, Andreas Neef, Matthew A Xu-Friedman
: Auditory nerve fibers encode sounds in the precise timing of action potentials (APs), which is used for such computations as sound localization. Timing information is relayed through several cell types in the auditory brainstem that share an unusual property: their APs are not overshooting, suggesting that the cells have very low somatic sodium conductance (gNa). However, it is not clear how gNa influences temporal precision. We addressed this by comparing bushy cells (BCs) in the mouse cochlear nucleus with T-stellate cells (SCs), which do have normal overshooting APs...
November 23, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/27879487/electrocochleography-in-cochlear-implant-recipients-with-residual-hearing-comparison-with-audiometric-thresholds
#10
Kanthaiah Koka, Aniket A Saoji, Leonid M Litvak
OBJECTIVES: To determine whether electrocochleography (ECoG) thresholds, especially cochlear microphonic and auditory nerve neurophonic thresholds, measured using an intracochlear electrode, can be used to predict pure-tone audiometric thresholds following cochlear implantation in ears with residual hearing. DESIGN: Pure-tone audiometric thresholds and ECoG waveforms were measured at test frequencies from 125 to 4000 Hz in 21 Advanced Bionics cochlear implant recipients with residual hearing in the implanted ear...
November 22, 2016: Ear and Hearing
https://www.readbyqxmd.com/read/27866146/hearing-preservation-after-penetrating-cochlear-injury
#11
George S Tarasidis, Richard H Wiggins, Richard K Gurgel
OBJECTIVES: To share results and recommendations for management of penetrating cochlear injury. METHODS: A patient underwent repair of a penetrating cochlear injury after a projectile led to a traumatic cochleostomy with a narrow miss of the facial nerve and intracranial carotid artery. RESULTS: Postoperatively, the patient's audiogram demonstrated a pure tone average of 47.5 dB for air conduction and 35 dB for bone conduction, worse in the high frequencies, with a Word Recognition Score of 76%...
November 19, 2016: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/27863625/facial-nerve-stimulation-following-cochlear-implantation-for-x-linked-stapes-gusher-syndrome-leading-to-identification-of-a-novel-pou3f4-mutation
#12
Jacob L Wester, Catherine Merna, Kevin A Peng, Rebecca Lewis, Ali R Sepahdari, Gail Ishiyama, Kumiko Hosokawa, Kozo Kumakawa, Akira Ishiyama
We report a case of a nine-year-old male who presented with facial nerve stimulation four years after cochlear implantation. Computed tomography was performed revealing a dilated internal auditory meatus and the cochlear implant electrode was found to be protruding into the fallopian canal at the level of the geniculate ganglion. Subsequent genetic analysis demonstrated X-linked deafness type 2 (DFNX2) caused by a novel c.769C > T nucleotide change in the POU domain, class 3, transcription factor 4 gene (POU3F4)...
December 2016: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/27861251/fast-click-rate-electrocochleography-and-auditory-brainstem-response-in-normal-hearing-adults-using-continuous-loop-averaging-deconvolution
#13
Wafaa A Kaf, Kelly M Lewis, Erdem Yavuz, Samantha M Dixon, Mark Van Ess, Abdullah M Jamos, Rafael E Delgado
OBJECTIVES: Using the continuous loop averaging deconvolution (CLAD) technique for conventional electrocochleography (ECochG) and auditory brainstem response (ABR) recordings, the effects of testing at high stimulus rates may have the potential to diagnose disorders of the inner ear and auditory nerve. First, a body of normative data using the CLAD technique must be established. DESIGN: Extratympanic click ECochG and ABR to seven stimulus rates using CLAD were measured simultaneously from a tympanic membrane electrode and surface electrodes on the forehead and mastoid of 42 healthy individuals...
November 16, 2016: Ear and Hearing
https://www.readbyqxmd.com/read/27860516/assessment-of-the-brainstem-mediated-stapedius-muscle-reflex-in-andean-children-living-at-high-altitudes
#14
S Allen Counter, Leo H Buchanan, Fernando Ortega, Anthony B Jacobs, Göran Laurell
Counter, S. Allen, Leo H. Buchanan, Fernando Ortega, Anthony B. Jacobs, and Göran Laurell. Assessment of the brainstem-mediated stapedius muscle reflex in Andean children living at high altitudes. High Alt Med Biol. 16:000-000, 2016.-This study examined the physiological thresholds, amplitude growth, and contraction duration of the acoustic stapedius reflex (ASR) in Andean children aged 2-17 years living at altitudes of 2850 m (Altitude I Group) and 3973 m (Altitude II Group) as part of a general medical assessment of the health status of the children...
November 18, 2016: High Altitude Medicine & Biology
https://www.readbyqxmd.com/read/27858100/-early-acoustic-evoked-potentials-in-patients-with-small-vestibular-schwannomas
#15
I Baljić, E Börner-Lünser, D Eßer, O Guntinas-Lichius
BACKGROUND: The prognostic potential of click-evoked early acoustic evoked potentials (EAEP) for vestibular schwannoma (VS) diagnostics is considered insufficient for tumors small than approximately <1.5 cm in diameter. However, up until now, the derivations at higher sound pressure levels have mainly been used for EAEP evaluation. The aim of this study was to examine whether registered EAEP are more sensitive to pathological changes at low sound pressure levels and with smaller tumors...
November 17, 2016: HNO
https://www.readbyqxmd.com/read/27837216/-the-heidelberg-ci-database-module-quality-control-in-hearing-restoration-with-cochlear-implants
#16
I T Herisanu, S Hoth, M Praetorius
BACKGROUND: Cochlear implants (CI) have been established as the therapy of choice for functional deafness. The number of CI-rehabilitated patients is continuously growing. The resulting data can provide important information for physicians, health insurance companies, and scientists. Assessment and structuring of data becomes more feasible with the application of modern database systems. MATERIALS AND METHODS: In collaboration with Innoforce Est., Liechtenstein, the authors developed a database module for the specific needs of CI patients...
December 2016: HNO
https://www.readbyqxmd.com/read/27837052/individual-differences-in-auditory-brainstem-response-wave-characteristics-relations-to-different-aspects-of-peripheral-hearing-loss
#17
Sarah Verhulst, Anoop Jagadeesh, Manfred Mauermann, Frauke Ernst
Little is known about how outer hair cell loss interacts with noise-induced and age-related auditory nerve degradation (i.e., cochlear synaptopathy) to affect auditory brainstem response (ABR) wave characteristics. Given that listeners with impaired audiograms likely suffer from mixtures of these hearing deficits and that ABR amplitudes have successfully been used to isolate synaptopathy in listeners with normal audiograms, an improved understanding of how different hearing pathologies affect the ABR source generators will improve their sensitivity in hearing diagnostics...
November 11, 2016: Trends in Hearing
https://www.readbyqxmd.com/read/27826999/the-new-classification-system-for-inner-ear-malformations-the-incav-system
#18
Zehra Hilal Adibelli, Leyla Isayeva, Ali Murat Koc, Tolgahan Catli, Hamit Adibelli, Levent Olgun
CONCLUSIONS: The proposed INCAV system standardizes reporting of inner ear malformations; gives adequate information about the structures of inner ear; defines the ears which could not be classified before; and helps in the selection of the ear as the cochlear implant candidate. Also it is easy-to-use for radiologists, and useful to the referring otolaryngologists. OBJECTIVE: This study was conducted to explore a more specific, definitive classification system which was based on radiological criteria for inner ear malformations...
November 9, 2016: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/27816972/vestibular-schwannoma-resection-with-ipsilateral-simultaneous-cochlear-implantation-in-patients-with-normal-contralateral-hearing
#19
Mario Sanna, María Del Mar Medina, Aldin Macak, Gianluca Rossi, Valerio Sozzi, Sampath Chandra Prasad
OBJECTIVE: To report the hearing results of cochlear implantation simultaneous to vestibular schwannoma (VS) resection by means of a translabyrinthine approach in patients with normal contralateral hearing. METHODS: This was a prospective study including adults with sporadic VS. Tumors were resected by means of a modified translabyrinthine approach with preservation of the cochlear nerve. RESULTS: A total of 13 patients underwent cochlear implantation...
November 5, 2016: Audiology & Neuro-otology
https://www.readbyqxmd.com/read/27815592/-intraoperative-monitoring-of-cochlear-nerve-function-during-cerebello-pontine-angle-surgery
#20
S Rampp, T Rahne, S K Plontke, C Strauss, J Prell
BACKGROUND: Surgical procedures in the cerebello-pontine angle (CPA), e. g. for vestibular schwannoma, have an increased risk for damage to the cochlear nerve. Consequently, hearing deterioration up to complete deafness may result with severe impact on quality of life. Methods for intraoperative monitoring of function may minimize such risks. OBJECTIVE: Review of current methods for intraoperative monitoring of the cochelar nerve and summary of new developments...
November 4, 2016: HNO
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