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https://www.readbyqxmd.com/read/28730266/-malignant-melanoma-current-status
#1
REVIEW
J K Winkler, K Buder-Bakhaya, A Dimitrakopoulou-Strauss, A Enk, J C Hassel
CLINICAL ISSUE: The incidence of malignant melanoma is continuously increasing. The prognosis of metastatic disease is still limited. STANDARD TREATMENT: Until a few years ago palliative chemotherapy with a limited response rate was the standard treatment for metastatic melanoma. TREATMENT INNOVATIONS: Immunotherapy and targeted therapy provide new treatment options. Immune checkpoint inhibitors have significantly improved the prognosis. DIAGNOSTIC WORK-UP: Regional lymph node sonography, computed tomography (CT) of the neck, chest and abdomen and brain magnetic resonance imaging (MRI) are routinely used...
July 20, 2017: Der Radiologe
https://www.readbyqxmd.com/read/28728712/diagnostic-imaging-and-newer-modalities-for-thoracic-diseases-pet-computed-tomographic-imaging-and-endobronchial-ultrasound-for-staging-and-its-implication-for-lung-cancer
#2
REVIEW
Sarah J Counts, Anthony W Kim
Modalities to detect and characterize lung cancer are generally divided into those that are invasive [endobronchial ultrasound (EBUS), esophageal ultrasound (EUS), and electromagnetic navigational bronchoscopy (ENMB)] versus noninvasive [chest radiography (CXR), computed tomography (CT), positron emission tomography (PET), and magnetic resonance imaging (MRI)]. This chapter describes these modalities, the literature supporting their use, and delineates what tests to use to best evaluate the patient with lung cancer...
August 2017: Surgical Clinics of North America
https://www.readbyqxmd.com/read/28725645/imaging-bronchopulmonary-dysplasia-a-multimodality-update
#3
REVIEW
Thomas Semple, Mohammed R Akhtar, Catherine M Owens
Bronchopulmonary dysplasia is the most common form of infantile chronic lung disease and results in significant health-care expenditure. The roles of chest radiography and computed tomography (CT) are well documented but numerous recent advances in imaging technology have paved the way for newer imaging techniques including structural pulmonary assessment via lung magnetic resonance imaging (MRI), functional assessment via ventilation, and perfusion MRI and quantitative imaging techniques using both CT and MRI...
2017: Frontiers in Medicine
https://www.readbyqxmd.com/read/28720694/myocardial-infarction-masquerading-as-myocarditis-in-a-patient-with-factor-v-leiden-unmasked-with-mr
#4
Jason Leo Walsh, Benjamin Howell Lole Harris, Walid Gharzuddine, Hussain Isma'eel
We present a case of a 21-year-old man presenting with sharp left-sided chest pain. A CT pulmonary angiogram was negative, ECG was unremarkable and a mild troponin rise was observed. Myocarditis was suspected as the most likely diagnosis, particularly in view of the patient's previous diagnosis of myocarditis 3 years prior. A cardiac MRI was indicative of an acute mid-anterior myocardial infarction (MI) and an old inferior MI with an associated aneurysm. A subsequent angiogram revealed a subtotal occlusion in the second diagonal artery, likely precipitated by homozygous factor V Leiden...
July 18, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28702770/oncologic-outcomes-after-treatment-for-mri-occult-breast-cancer-pt0n
#5
Damian P McCartan, Emily C Zabor, Monica Morrow, Kimberly J Van Zee, Mahmoud B El-Tamer
BACKGROUND: Studies assessing outcomes in occult breast cancer have often included women treated before the routine use of magnetic resonance imaging (MRI). This study examined outcomes for patients presenting with axillary adenopathy and no primary breast tumor detectable by MRI or other imaging methods. METHODS: All patients with axillary nodal metastases consistent with breast carcinoma and no breast primary tumor detectable by physical exam, mammography, or MRI treated between 1 January 1996 and 30 June 2011 were identified from an institutional database...
July 12, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28698444/-a-case-of-central-diabetes-insipidus-that-was-caused-by-pituitary-metastasis-of-lung-adenocarcinoma-and-was-controlled-by-radiation-therapy
#6
Yusuke Izumi, Takeshi Masuda, Shinji Nabeshima, Yasushi Horimasu, Taku Nakashima, Shintaro Miyamoto, Hiroshi Iwamoto, Kazunori Fujitaka, Yuji Murakami, Hironobu Hamada, Yasushi Nagata, Noboru Hattori
BACKGROUND: Pituitary metastasis of lung cancer is rare; however, it often causes diabetes insipidus. Although the majority of such patients are treated with radiation therapy, it remains unclear whether diabetes insipidus can be controlled by radiation therapy. CASE: A 72-year-old man was admitted to our hospital for hemosputum, headache, and polyuria. A chest CT scan showed a 3.0 cm mass in the left upper lobe of his lung. Bronchofiberscopy results confirmed the pathological diagnosis of lung adenocarcinoma...
June 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/28693983/a-prospective-randomized-study-comparing-centrifugation-and-sedimentation-for-fat-grafting-in-breast-reconstruction
#7
I Sarfati, R F D van la Parra, C A Terem-Rapoport, D Benyahi, C Nos, K B Clough
BACKGROUND: Fat grafting is an efficient method to correct large volumetric defects after mastectomy. There is an ongoing debate regarding the best method of processing the harvested fat before fat grafting. This study aimed to introduce a new MRI model and to compare two fat processing techniques measuring the gain in soft tissue thickness after fat grafting to the chest wall. METHODS: Fifty-one mastectomy patients (one double sided), who required delayed implant reconstruction, with poor skin conditions were proposed fat grafting prior to implant reconstruction...
June 17, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28693276/examination-of-the-predictive-factors-of-the-response-to-whole-brain-radiotherapy-for-brain-metastases-from-lung-cancer-using-mri
#8
Shuri Aoki, Tomonori Kanda, Noriyuki Matsutani, Nobuhiko Seki, Masafumi Kawamura, Shigeru Furui, Hideomi Yamashita
Previous studies have been conducted on the prognostic factors for overall survival in patients with brain metastases (BMs) following whole brain radiotherapy (WBRT). However, there have been a small number of studies regarding the prognostic factors for the response of tumor to WBRT. The aim of the present study was to identify the predictive factors for the response to WBRT from the point of view of reduction of tumor using magnetic resonance imaging. A retrospective analysis of 62 patients with BMs from primary lung cancer treated with WBRT was undertaken...
July 2017: Oncology Letters
https://www.readbyqxmd.com/read/28690355/evaluation-of-lung-tumor-motion-management-in-radiation-therapy-with-dynamic-mri
#9
Seyoun Park, Rana Farah, Steven M Shea, Erik Tryggestad, Russell Hales, Junghoon Lee
Surrogate-based tumor motion estimation and tracing methods are commonly used in radiotherapy despite the lack of continuous real time 3D tumor and surrogate data. In this study, we propose a method to simultaneously track the tumor and external surrogates with dynamic MRI, which allows us to evaluate their reproducible correlation. Four MRI-compatible fiducials are placed on the patient's chest and upper abdomen, and multi-slice 2D cine MRIs are acquired to capture the lung and whole tumor, followed by two-slice 2D cine MRIs to simultaneously track the tumor and fiducials, all in sagittal orientation...
February 11, 2017: Proceedings of SPIE
https://www.readbyqxmd.com/read/28686656/avoiding-fears-and-promoting-shared-decision-making-how-should-physicians-inform-patients-about-radiation-exposure-from-imaging-tests
#10
Blanca Lumbreras, José Vilar, Isabel González-Álvarez, Mercedes Guilabert, María Pastor-Valero, Lucy Anne Parker, Jorge Vilar-Palop, Ildefonso Hernández-Aguado
OBJECTIVE: We aimed to evaluate the population's awareness about the radiation exposure associated with five specific imaging tests, and their preference regarding three different formats for receiving the information before undergoing an imaging test. METHODS: A quantitative and qualitative evaluation through a survey and focal groups including general population from two health departments in Spain. The sampling was carried out in stages (according to health department size) and stratified by age and sex, to get a representative sample...
2017: PloS One
https://www.readbyqxmd.com/read/28684728/a-rare-case-of-sarcomatoid-carcinoma-of-the-lung-with-spine-metastasis-including-a-literature-review
#11
Hafiza Sobia Arshad, Rizwan Ahmed Dudekula, Masooma Niazi, Sandeep Malik, Misbahuddin Khaja
BACKGROUND Sarcomatoid carcinoma is a rare, aggressive, malignant cancer composed of sarcoma and sarcoma-like components, and can occur in different organs such as the thyroid gland, bone, skin, breast, pancreas, liver, urinary tract, and lung. Pulmonary sarcomatoid carcinoma accounts for only a small percentage of lung cancers and has histological variants that include pleomorphic carcinoma, giant cell carcinoma, spindle cell carcinoma, carcinosarcoma, and pulmonary blastoma. CASE REPORT Here, we present a case of sarcomatoid carcinoma in a 63-year-old HIV-positive Hispanic male who presented with back pain, dry cough, and weight loss...
July 7, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28674910/diagnostic-imaging-in-pediatric-thoracic-trauma
#12
Claudia Lucia Piccolo, Stefania Ianniello, Margherita Trinci, Michele Galluzzo, Michele Tonerini, Massimo Zeccolini, Giuseppe Guglielmi, Vittorio Miele
Thoracic trauma accounts for approximately 14% of blunt force traumatic deaths, second only to head injuries. Chest trauma can be blunt (90% of cases) or penetrating. In young patients, between 60 and 80% of chest injuries result from blunt trauma, with over half as a consequence of impact with motor vehicles, whereas in adolescents and adults, penetrating trauma has a statistically more prominent role. Pulmonary contusions and rib fractures are the most frequent injuries occurring. Chest X-ray is the first imaging modality of choice to identify patients presenting with life-threatening conditions (i...
July 4, 2017: La Radiologia Medica
https://www.readbyqxmd.com/read/28668148/large-left-ventricular-aneurysm-and-multifocal-myocardial-involvement-in-a-patient-with-systemic-sclerosis
#13
Luca Olivotti, Deborah Cosmi, Annamaria Nicolino, Luigi Martinelli, Shahram Moshiri, Gian Battista Danzi
A 43-year-old man with systemic sclerosis and chest pain had negative T waves in precordial electrocardiographic leads. The echocardiogram showed a large left ventricular apical accessory chamber. The coronary arteries were normal. Cardiac magnetic resonance imaging (MRI) showed a large fibrotic aneurysm and a small patch of midwall late enhancement in the septum. The aneurysm was surgically removed. At the 8-month follow-up, cardiac MRI showed the appearance of a new nodular lesion in the anterior wall, causing a localized wall motion abnormality...
July 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28664012/cerebral-infarction-arising-from-takotsubo-cardiomyopathy-case-report-and-literature-review
#14
Yoshihiro Otani, Koji Tokunaga, Satoshi Kawauchi, Satoshi Inoue, Kyoichi Watanabe, Hideki Kiriyama, Kosuke Sakane, Kiyoaki Maekawa, Isao Date, Kengo Matsumoto
Although most patients with takotsubo cardiomyopathy have a favorable outcome, complications are not uncommon. Recent studies have reported an increase in incidence of cardioembolic complications; however, the association between takotsubo cardiomyopathy and stroke, in particular thromboembolic cerebral infarction, remains unclear. We reported a 44-year-old woman who had a cerebral infarction resulting from takotsubo cardiomyopathy. She had felt chest discomfort a few days prior to infarction, and later developed left hemiparesis...
October 2016: NMC Case Rep J
https://www.readbyqxmd.com/read/28663358/necrotising-coronaritis-with-fatal-outcome
#15
Lisa Schweizer, Nadja Fischer, Thomas Fehr, Stephan Schneiter
A 56-year-old woman presented with acute onset of typical chest pain. She was diagnosed with acute coronary syndrome with ST-segment elevation myocardial infarction. Although significant obstructive coronary artery disease was ruled out by coronary angiography, cardiac MRI showed transmural necrosis of the lateral free wall with extensive microvascular obstruction consistent with ischaemic heart disease. Within 48 hours after initial presentation, the patient suddenly arrested due to pulseless electrical activity with futile resuscitation efforts...
June 28, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28659571/chest-pain-and-sudden-onset-paraplegia-at-the-emergency-department-an-uncommon-presentation
#16
Feng Han Chiu, Shih Hung Tsai, Cheng Hsuan Ho
BACKGROUND Coarctation of the aorta is characterized by narrowing of the descending aorta. The narrowing typically is at the isthmus, the segment just distal to the left subclavian artery. Adults with undiagnosed aortic coarctation are asymptomatic or may present with nonspecific hypertension. We present a case that highlights the uncommon complication of aortic coarctation with spinal compression syndrome. CASE REPORT A 45-year-old male presented to the emergency department (ED) with acute-onset chest pain; he experienced urinary incontinence and bilateral lower limb weakness during his ED visit...
June 29, 2017: American Journal of Case Reports
https://www.readbyqxmd.com/read/28659368/giant-lipoma-of-the-hand-causing-median-nerve-compression
#17
Kevin Clesham, John Gerard Galbraith, Ashok Ramasamy, Ahmed Karkuri
Lipomas are benign neoplasms derived from adipose tissue composed of mature adipocytes. They account for almost 50% of all soft-tissue neoplasms and occur in up to 2% of the population. They usually present asymptomatically as solitary discrete mobile lumps found most commonly on the neck, upper back, proximal limbs and chest. In less than 1% of cases, they can be found in the distal extremities.We discuss the case of a 65-year-old man who presented with a 2-year history of a slowly enlarging left palm swelling, with recent-onset numbness and loss of power in the distribution of the median nerve...
June 28, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28658104/thrombotic-complications-and-tip-position-of-transjugular-chronic-dialysis-catheter-scheduled-into-superior-vena-cava-findings-on-hr-mrcp-and-hr-t2wi
#18
Whenzheng Li, Fang Li, He Wang, Xueying Long, Obin Ghimire, Yigang Pei, Xiangcheng Xiao, Jianping Ning
BACKGROUND: Catheter-related thrombotic complications(TCs) can occur during the long term use of a chronic dialysis catheter (CDC), including fibrin sheath (FS), mural thrombosis (MT), venous thrombosis (VT), and intraluminal clots (IC), which has not been reported with MRI. The aim of our study was to evaluate the determination of catheter tip position (TP) and resolution of TCs in patients with transjugular CDC scheduled into the superior vena cava using high resolution magnetic resonance cholangiopancreatography (HR-MRCP) and T2-weighted imaging (HR-T2WI)...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28648525/-18-f-fdg-pet-ct-in-a-cardiac-metastasis-in-a-patient-with-history-of-malignant-neuroectodermal-tumour-of-the-chest-wall-case-report-and-review-of-the-literature
#19
J A Marroquín, A C Hernández, J P Pilkington, A Saviatto, M J Tabuenca, J M Estenoz
The case presented is a 25-year-old male with a malignant neuroectodermal tumour on the left chest wall (Askin tumour), treated with surgery after neoadyuvant chemotherapy and followed by consolidation chemotherapy. After 9 years of disease free survival, the patient developed an acute pulmonary embolism. The echocardiogram, thoracic CT, and cardiac MRI scans revealed a mass in the right atrium. Recurrence of an Askin tumour versus an atrium myxoma was suspected. (18)F-FDG PET/CT showed an intense hypermetabolic right atrium mass with extension to the right ventricle highly suggestive of malignancy...
June 22, 2017: Revista Española de Medicina Nuclear e Imagen Molecular
https://www.readbyqxmd.com/read/28648435/current-concepts-of-diagnosis-and-management-of-pericardial-cysts
#20
REVIEW
Sandeep Kumar Kar, Tanmoy Ganguly
Pericardial cysts are rare with an incidence of about 1 in every 100,000 persons and one in 10 pericardial cysts may actually be a pericardial diverticulum. Pericardial cysts and diverticula share similar developmental origin and may appear as an incidental finding in chest roentgenogram in an asymptomatic patient. CT scan is considered as best modality for diagnosis and delineation of the surrounding anatomy. Cardiac MRI is recommended in the evaluation of the compressive effects caused by the pericardial cysts...
May 2017: Indian Heart Journal
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