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https://www.readbyqxmd.com/read/28710581/validation-of-a-model-for-predicting-smear-positive-active-pulmonary-tuberculosis-in-patients-with-initial-acid-fast-bacilli-smear-negative-sputum
#1
Jun -Jun Yeh
OBJECTIVES: The objective of this study was to develop a predictive model for final smear-positive (SP) active pulmonary tuberculosis (aPTB) in patients with initial negative acid fast bacilli (AFB) sputum smears (iSN-SP-aPTB) based on high-resolution computed tomography (HRCT). METHOD AND MATERIALS: Eighty (126, 21) patients of iSN-SP-aPTB and 402 (459, 876) patients of non-initial positive acid fast bacilli (non-iSP) pulmonary disease without iSN-SP-aPTB were included in a derivation (validation, prospective) cohort...
July 14, 2017: European Radiology
https://www.readbyqxmd.com/read/28708797/role-of-multislice-ct-imaging-in-predicting-the-visibility-of-the-round-window-in-pediatric-cochlear-implantation
#2
Yasser A Fouad, Ahmad Shaker Elaassar, Mohammad Waheed El-Anwar, Ebrahim Sabir, Ahmad Abdelhamid, Mai Ghonimy
BACKGROUND: High-resolution computed tomography (HRCT) magnifies the role of preoperative imaging for detailed inner and middle ear anatomical information and enhances more efforts for better dependent correlation and measurements of round window (RW). OBJECTIVE: To find an applicable way by HRCT imaging for the prediction of the visibility of the RW during cochlear implantation (CI) surgery. METHODS: Five radiologic measurements were performed on the axial HRCT and these measurements were correlated with the degree of RW visibility after performing posterior tympanotomy during CI surgery...
July 13, 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/28707988/first-clinical-report-of-helical-tomotherapy-with-simultaneous-integrated-boost-for-synchronous-bilateral-breast-cancer
#3
Tabassum Wadasadawala, Shanu Jain, Siji Paul, Reena Phurailatpam, Kishore Joshi, Palak Popat, Sandip Tandon, Aruna Alahari, Rajiv Sarin
OBJECTIVE: Radiotherapy for synchronous bilateral breast cancer (SBBC) is technically very challenging. This study reports the clinical feasibility, dosimetry and safety of helical tomotherapy (HT) with simultaneous integrated boost (SIB) in patients treated with adjuvant radiotherapy for SBBC. MATERIAL AND METHODS: Twenty one women with SBBC treated with HT from January 2013 to June 2016 were retrospectively evaluated. Radiation lung toxicity was assessed using pulmonary function test (PFT) and high resolution computerized tomography scan (HRCT) scan at baseline and 1 year post RT in 18 patients...
July 14, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28705995/reproducibility-of-airway-luminal-size-in-asthma-measured-by-hrct
#4
Robert H Brown, Robert J Henderson, Elizabeth A Sugar, Janet T Holbrook, Robert A Wise
High resolution computed tomography (HRCT) is a well-established imaging technology to measure lung and airway morphology in vivo. However, there is a surprising lack of studies examining HRCT reproducibility. The CPAP trial was a multicenter, randomized, 3-parallel arm, sham-controlled 12 week clinical trial to assess the use of a nocturnal CPAP device on airways reactivity to methacholine. The lack of a treatment effect of CPAP on clinical or HRCT measures provided an opportunity for the current analysis...
July 13, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28697481/childhood-exposure-to-libby-amphibole-asbestos-and-respiratory-health-in-young-adults
#5
Patrick H Ryan, Carol H Rice, James E Lockey, Brad Black, Jeff Burkle, Timothy J Hilbert, Linda Levin, Cole Brokamp, Roy McKay, Christopher Wolfe, Grace K LeMasters
OBJECTIVES: Vermiculite ore containing Libby amphibole asbestos (LAA) was mined in Libby, MT, from the 1920s-1990. Recreational and residential areas in Libby were contaminated with LAA. This objective of this study was to characterize childhood exposure to LAA and investigate its association with respiratory health during young adulthood. METHODS: Young adults who resided in Libby prior to age 18 completed a health and activity questionnaire, pulmonary function testing, chest x-ray and HRCT scan...
July 8, 2017: Environmental Research
https://www.readbyqxmd.com/read/28695785/ct-study-of-the-arytenoid-cartilage-in-patients-with-laryngeal-contact-granuloma
#6
Jinrang Li, Shiyu Tian, Shizhen Zou, Qingjun Wang, Xuhui Tai, Xuesong Chen
Objective To explore high-resolution computed tomography (HRCT) characteristics of arytenoid cartilage in patients with laryngeal contact granuloma (LCG). Setting Tertiary hospitals. Study Design Individual case-control study. Methods HRCT scans were obtained before treatment from 42 patients with LCG. Similar scans were obtained from 50 patients with glottic laryngeal cancer or vocal cord leukoplakia without vocal process involvement. Results Forty-two male patients with LCG were enrolled in the study. There were 41 patients with unilateral vocal cord lesions, and 1 patient had bilateral lesions...
July 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28694803/comparative-genomics-identifies-a-novel-conserved-protein-hpat-in-proteobacterial-type-iii-secretion-systems-that-do-not-possess-the-putative-translocon-protein-hrpf
#7
Céline Pesce, Jonathan M Jacobs, Edwige Berthelot, Marion Perret, Taca Vancheva, Claude Bragard, Ralf Koebnik
Xanthomonas translucens is the causal agent of bacterial leaf streak, the most common bacterial disease of wheat and barley. To cause disease, most xanthomonads depend on a highly conserved type III secretion system, which translocates type III effectors into host plant cells. Mutagenesis of the conserved type III secretion gene hrcT confirmed that the X. translucens type III secretion system is required to cause disease on the host plant barley and to trigger a non-host hypersensitive response (HR) in pepper leaves...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28688028/novel-assessment-of-interstitial-lung-disease-using-the-computer-aided-lung-informatics-for-pathology-evaluation-and-rating-caliper-software-system-in-idiopathic-inflammatory-myopathies
#8
Patompong Ungprasert, Katelynn M Wilton, Floranne C Ernste, Sanjay Kalra, Cynthia S Crowson, Srinivasan Rajagopalan, Brian J Bartholmai
PURPOSE: To evaluate the correlation between measurements from quantitative thoracic high-resolution CT (HRCT) analysis with "Computer-Aided Lung Informatics for Pathology Evaluation and Rating" (CALIPER) software and measurements from pulmonary function tests (PFTs) in patients with idiopathic inflammatory myopathies (IIM)-associated interstitial lung disease (ILD). METHODS: A cohort of patients with IIM-associated ILD seen at Mayo Clinic was identified from medical record review...
July 7, 2017: Lung
https://www.readbyqxmd.com/read/28683126/can-we-differentiate-minimally-invasive-adenocarcinoma-and-non-invasive-neoplasms-based-on-high-resolution-computed-tomography-features-of-pure-ground-glass-nodules
#9
Xiaoye Wang, Lihua Wang, Weisheng Zhang, Hong Zhao, Feng Li
OBJECTIVE: The purpose of our study was to assess the differentially diagnostic value of radiographic characteristics of pure ground glass nodules (GGNs) between minimally invasive adenocarcinoma and non-invasive neoplasm. METHODS: Sixty-seven pure GGNs (28 minimally invasive adenocarcinomas (MIA) and 39 pre-invasive lesions) were analyzed from June 2012 to June 2015. Pre-invasive lesions consisted of 15 atypical adenomatous hyperplasia (AAH) and 24 adenocarcinomas in situ (AIS)...
2017: PloS One
https://www.readbyqxmd.com/read/28673104/biopsy-in-idiopathic-pulmonary-fibrosis-back-to-the-future
#10
Giulio Rossi, Paolo Spagnolo
Idiopathic Pulmonary Fibrosis (IPF) is a relentlessly progressive, fibrosing interstitial pneumonia characterized by a radiologic and/or histologic pattern of usual interstitial pneumonia (UIP). The availability of two effective anti-fibrotic drugs in IPF has encouraged the identification and treatment of patients in early stages in order to maximize clinical benefit. The ability of high-resolution computed tomography (HRCT) to identify a 'definite' UIP pattern is suboptimal, particularly in the absence of honeycombing...
July 10, 2017: Expert Review of Respiratory Medicine
https://www.readbyqxmd.com/read/28673006/comparison-of-the-gas-liquid-dual-support-fixation-and-heitzman-fixation-techniques-for-preparing-lung-specimens
#11
Dongsheng Yu, Weili Qu, Haipeng Xia, Xiaofeng Li, Zhenfeng Luan, Renjie Yan, Xiaodong Lu, Peng Zhao
The aim of the present study was to compare the gas-liquid dual support fixation and Heitzman fixation techniques for the preparation of lung specimens. A total of 40 fresh lung samples were surgically collected from 40 male patients with lung cancer by biopsy. Patients were recruited from the Affiliated Hospital of Qingdao University Medical College (Qingdao, China) between July 2007 and June 2014. Samples were prepared using either the gas-liquid dual support fixation method (group A; n=26) or the Heitzman fixation method (group B; n=14)...
July 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28672974/efficacies-of-rosiglitazone-and-retinoin-on-bleomycin-induced-pulmonary-fibrosis-in-rats
#12
Wencheng Yu, Liyun Mi, Teng Long
The present study investigated the intervention efficacies of rosiglitazone (ROS) and retinoin (RET) on bleomycin-induced pulmonary fibrosis in rats. A total of 48 rats were randomly divided into the control group (group C), the model group (group M), the dexamethasone group (group D), the ROS group (group R), the RET group (group W) and the ROS + RET group (group L). Group M and the treatment groups were intratracheally injected with 5 mg/kg bleomycin, while group C was injected with saline. The lungs of rats in each group were inspected using high resolution computed tomography (HRCT), lung tissue hematoxylin and eosin staining and Masson staining; furthermore, lung L-hydroxyproline (Hyp) content and the concentration of transforming growth factor β1 (TGF-β1) serum of each group were also determined...
July 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28670025/high-resolution-computed-tomography-findings-in-eight-patients-with-hantavirus-pulmonary-syndrome
#13
Diego de Lacerda Barbosa, Bruno Hochhegger, Arthur Soares Souza, Gláucia Zanetti, Dante Luiz Escuissato, Gustavo de Souza Portes Meirelles, Marcelo Buarque de Gusmão Funari, Edson Marchiori
OBJECTIVE: The purpose of this study was to describe the high-resolution computed tomography (HRCT) findings in patients with hantavirus pulmonary syndrome (HPS). MATERIALS AND METHODS: We retrospectively reviewed HRCT findings from eight cases of HPS. All patients were men, aged 19-70 (mean, 41.7) years. Diagnoses were established by serological test (enzyme-linked immunosorbent assay) in all patients. Two chest radiologists analyzed the images and reached decisions by consensus...
May 2017: Radiologia Brasileira
https://www.readbyqxmd.com/read/28668422/effects-of-pure-and-hybrid-iterative-reconstruction-algorithms-on-high-resolution-computed-tomography-in-the-evaluation-of-interstitial-lung-disease
#14
Masaki Katsura, Jiro Sato, Masaaki Akahane, Yoko Mise, Kaoru Sumida, Osamu Abe
OBJECTIVES: To compare image quality characteristics of high-resolution computed tomography (HRCT) in the evaluation of interstitial lung disease using three different reconstruction methods: model-based iterative reconstruction (MBIR), adaptive statistical iterative reconstruction (ASIR), and filtered back projection (FBP). METHODS: Eighty-nine consecutive patients with interstitial lung disease underwent standard-of-care chest CT with 64-row multi-detector CT...
August 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28667653/occurrence-of-bronchial-anthracofibrosis-in-respiratory-symptomatics-with-exposure-to-biomass-fuel-smoke
#15
Vikas Pilaniya, Shekhar Kunal, Ashok Shah
INTRODUCTION: Bronchial anthracofibrosis (BAF), confirmed bronchoscopically, is characterised by bluish-black mucosal pigmentation and distortion/narrowing of the bronchus. We investigated the occurrence of BAF in respiratory symptomatics with biomass fuel smoke exposure and evaluated its clinico-radiological attributes and impact on functional status. MATERIAL AND METHODS: Of the eighty subjects evaluated, 60 consented for fiberoptic bronchoscopy (FOB). All 60 subjects also underwent chest radiography, high resolution computed tomography (HRCT) of the thorax, complete pulmonary function testing including diffusion capacity and six-minute-walk test...
2017: Advances in Respiratory Medicine
https://www.readbyqxmd.com/read/28649310/lung-ultrasound-has-limited-diagnostic-value-in-rare-cystic-lung-diseases-a-cross-sectional-study
#16
Jesper Rømhild Davidsen, Elisabeth Bendstrup, Daniel P Henriksen, Ole Graumann, Christian B Laursen
Background: Lung ultrasound (LUS) used to identify interstitial syndrome (IS) and pleural thickening related to diffuse parenchymal lung disease (DPLD) has shown significant correlations with ground glass opacity (GGO) on high-resolution computed tomography (HRCT). However, the applicability of LUS in patients with DPLD subtypes as rare cystic lung diseases has not previously been investigated. This study aimed to observe if distinctive LUS findings could be found in patients with lymphangioleiomyomatosis (LAM), pulmonary Langerhans cell histiocytosis (PLCH), and Birt-Hogg-Dubé syndrome (BHDS)...
2017: European Clinical Respiratory Journal
https://www.readbyqxmd.com/read/28641716/the-effects-of-pleural-plaques-on-longitudinal-lung-function-in-vermiculite-miners-of-libby-montana
#17
Kathleen A Clark, J Jay Flynn, Wilfried J J Karmaus, Lawrence C Mohr
BACKGROUND: This study was conducted to assess associations of pleural plaques (PP) and longitudinal lung function in vermiculite miners of Libby, Montana who are occupationally exposed to asbestos. High-resolution computed tomography (HRCT) was used to identify asbestos-related findings in former Libby vermiculite miners. We investigated annual lung function decline in miners with PP only and compared them to miners with normal HRCT findings. MATERIALS AND METHODS: HRCTs from 128 miners were categorized into the following 4 diagnostic groups: (1) normal computed tomography scan (n = 9); (2) PP only (n = 72); (3) PP and interstitial fibrosis (n = 26) and (4) additional HRCT abnormalities (n = 21) such as rounded atelectasis, diffuse pleural thickening, pleural effusions or pulmonary nodules or tumor >1cm in diameter...
June 2017: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/28641325/superior-canal-dehiscence-syndrome-associated-with-scuba-diving
#18
Naoharu Kitajima, Akemi Sugita-Kitajima, Seiji Kitajima
A 28-year-old female diver presented with dizziness and difficulty clearing her left ear whilst scuba diving. Her pure-tone audiometry and tympanometry were normal. Testing of Eustachian tube function revealed tubal stenosis. Video-oculography revealed a predominantly torsional nystagmus while the patient was in the lordotic position. Fistula signs were positive. High-resolution computed tomography (HRCT) of the temporal bone revealed a diagnosis of bilateral superior semicircular canal dehiscence (SCDS). Cervical vestibular-evoked myogenic potential (cVEMP) testing showed that the amplitude of the cVEMP measured from her left ear was larger than that from the right...
June 2017: Diving and Hyperbaric Medicine: the Journal of the South Pacific Underwater Medicine Society
https://www.readbyqxmd.com/read/28640655/usual-interstitial-pneumonia-can-be-detected-in-transbronchial-biopsies-using-machine-learning
#19
Daniel G Pankratz, Yoonha Choi, Urooj Imtiaz, Grażyna M Fedorowicz, Jessica D Anderson, Thomas V Colby, Jeffrey L Myers, David A Lynch, Kevin K Brown, Kevin R Flaherty, Mark P Steele, Steve D Groshong, Ganesh Raghu, Neil M Barth, P Sean Walsh, Jing Huang, Giulia C Kennedy, Fernando J Martinez
RATIONALE: Usual interstitial pneumonia (UIP) is the histopathologic hallmark of idiopathic pulmonary fibrosis. While UIP can be detected by high-resolution computed tomography (HRCT) of the chest, HRCT results are frequently inconclusive, and pathology from transbronchial biopsy (TBB) has poor sensitivity. Surgical lung biopsy (SLB) may be necessary for a definitive diagnosis. OBJECTIVES: To develop a genomic classifier in tissue obtained by TBB that distinguishes UIP from non-UIP, trained against central pathology as the reference standard...
June 22, 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/28637047/pleural-adhesion-assessment-as-a-predictor-for-pneumothorax-after-endobronchial-valve-treatment
#20
Wouter H van Geffen, Karin Klooster, Jorine E Hartman, Nick H T Ten Hacken, Huib A M Kerstjens, Rienhart F E Wolf, Dirk-Jan Slebos
BACKGROUND: Pneumothorax after bronchoscopic lung volume reduction using one-way endobronchial valves (EBVs) in patients with advanced emphysema occurs in approximately 20% of patients. It is not well known which factors predict the development of pneumothorax. OBJECTIVE: To assess whether pleural adhesions on pretreatment high-resolution computed tomography (HRCT) scans are associated with pneumothorax occurrence after EBV treatment. METHODS: HRCT scan analyses were performed on all patients who received EBV treatment in a randomized controlled trial...
2017: Respiration; International Review of Thoracic Diseases
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