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Uric acid AND pulse wave velocity

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https://www.readbyqxmd.com/read/29696164/the-design-and-rationale-of-the-beijing-vascular-disease-patients-evaluation-study-best-study
#1
Huan Liu, Jinbo Liu, Hongwei Zhao, Lihong Li, Guangyun Shang, Yingyan Zhou, Hongyu Wang
Aims: Arteriosclerosis and arterial stiffness increasing are the basic pathophysiological changes of vascular-related diseases, and also the predictor factors of future cardiovascular events. Plasma biomarkers such as glucose, lipids, Homocysteine (Hcy), N-terminal pro-brain natriuretic peptide (NT-proBNP) have been shown to be involved the development of arteriosclerosis. The present study is a prospective observational and follow-up study of the characteristics of subclinical vascular disease detected by non-invasive methods that can predict progression of clinical overt vascular events in a Chinese population...
September 2017: Contemporary Clinical Trials Communications
https://www.readbyqxmd.com/read/29660007/uric-acid-is-not-associated-with-diabetic-nephropathy-and-other-complications-in-type-1-diabetes
#2
Sascha Pilemann-Lyberg, Tine Willum Hansen, Frederik Persson, Simone Theilade, Tarunveer Singh Ahluwalia, Jan Frystyk, Peter Rossing
Background: To examine the association between plasma uric acid (UA) and the presence of diabetic complications including diabetic nephropathy and cardiovascular risk factors in patients with type 1 diabetes. Methods: This study, which is cross-sectional in design, included 676 Caucasian type 1 diabetes patients from the Steno Diabetes Center Copenhagen. Participants with UA within the three lowest sex-specific quartiles were compared with participants with levels in the highest quartile...
April 11, 2018: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/29651957/serum-uric-acid-elevation-is-associated-to-arterial-stiffness-in-hypertensive-patients-with-metabolic-disturbances
#3
Agustin J Ramirez, Alejandra Ines Christen, Ramiro A Sanchez
INTRODUCTION: Chronic serum uric acid elevation (SUA) is known to be induced by dyslipidemia, hypertension, inflammation, and insulin resistance. Therefore, it has been associated with higher risk for coronary artery disease and cardiovascular mortality. Also, increased levels of SUA have been associated with regional arterial stiffness, assessed by pulse wave velocity (PWV). AIMS: To evaluate the relationships of PWV, SUA and different metabolic parameters in essential hypertensive patients...
April 13, 2018: Current Hypertension Reviews
https://www.readbyqxmd.com/read/29587296/the-relationships-of-the-fractional-excretion-of-uric-acid-with-brachial-ankle-pulse-wave-velocity-and-ankle-brachial-index-in-chinese-young-adults
#4
Jia-Wen Hu, Yang Wang, Chao Chu, Yu Yan, Keke Wang, Wenling Zheng, Qiong Ma, Yong-Bo Lv, Yin Deng, Bo Yan, Jian-Jun Mu
BACKGROUND/AIMS: Elevated serum uric acid (UA) was intimately correlated with vascular stiffness and abnormal ankle brachial index (ABI) in various populations. These correlations lost significance after adjustment for estimated glomerular filtration rate (eGFR), indicating that the association of UA and brachial-ankle pulse wave velocity (baPWV) or ABI might be driven by kidney function. UA is predominantly eliminated through the kidneys, and metabolic disorders can influence the clearance of UA...
2018: Kidney & Blood Pressure Research
https://www.readbyqxmd.com/read/29580767/fatty-liver-index-is-associated-to-pulse-wave-velocity-in-healthy-subjects-data-from-the-brisighella-heart-study
#5
Arrigo F G Cicero, Stefano Gitto, Federica Fogacci, Martina Rosticci, Marina Giovannini, Sergio D'Addato, Pietro Andreone, Claudio Borghi
BACKGROUND: Non-Alcoholic Fatty Liver Disease (NAFLD) is associated to increased risk of cardiovascular disease. Our aim was to evaluate association of indexes of fatty liver with arterial stiffness (AS). METHODS: We analyzed data of adult volunteers visited during the last Brisighella survey. We evaluated the Pulse Wave Velocity (PWV) and the following non-invasive indexes of liver steatosis: Fatty Liver Index (FLI), Lipid Accumulation Product (LAP), Hepatic Steatosis Index (HSI)...
March 23, 2018: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/29572081/ldl-oxidation-serum-uric-acid-kidney-function-and-pulse-wave-velocity-data-from-the-brisighella-heart-study-cohort
#6
Arrigo F G Cicero, Masanari Kuwabara, Richard Johnson, Marilisa Bove, Federica Fogacci, Martina Rosticci, Marina Giovannini, Sergio D'Addato, Claudio Borghi
BACKGROUND: Serum uric acid (SUA) and oxidized LDL (oxLDL) may be associated with arterial aging. The aim of our study was to evaluate the relationship between SUA, oxLDL and arterial stiffness in subjects with normal renal function and in patients with mild or moderate renal impairment. METHODS: From the database of the 2012 Brisighella Heart Study, we compared age-matched adult, non-smoker subjects without cardiovascular disease and with normal renal function (n = 205), subjects with stage II chronic kidney disease (CKD) (n = 118) and subjects with stage III CKD (n = 94)...
June 15, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29561733/cardiovascular-risk-factors-in-a-roma-sample-population-from-romania
#7
Emma Weiss, Cristina Japie, Ana Maria Balahura, Daniela Bartos, Elisabeta Badila
BACKGROUND: The Roma population has a high prevalence of cardiovascular risk factors, higher mortality, and shorter life expectancy. It is found in largest numbers in Romania, but published data are still scarce here. We studied cardiovascular risk factors and disease along with target organ damage on a population of Roma inhabitants from Bucharest, Romania. METHODS: This cross-sectional study enrolled, in a community-based participatory research manner, 806 Roma subjects (18-83 years)...
March 19, 2018: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/29386306/brachial-ankle-pulse-wave-velocity-could-be-a-predictor-of-mortality-in-patients-on-peritoneal-dialysis
#8
Lailiang Wang, Qun Luo, Beixia Zhu, Fangfang Zhou
BACKGROUND AND OBJECTIVE: Elevated pulse wave velocity (PWV) has been associated with higher mortality in the general population, chronic kidney disease (CKD) patients, and hemodialysis patients. However, in peritoneal dialysis (PD) patients, this association has received little attention. The aim of this study was to evaluate the association between baseline brachial-ankle PWV (baPWV) levels and total mortality in PD patients. METHODS: In this single-center retrospective cohort study, 254 incident PD patients with baseline baPWV were followed up from 1 January 2013 to 31 July 2016...
January 31, 2018: Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis
https://www.readbyqxmd.com/read/29366042/ldl-oxidation-serum-uric-acid-and-pulse-wave-velocity-relationship-in-chronic-kidney-disease-data-from-the-brisighella-heart-study-cohort
#9
Arrigo Cicero, Marilisa Bove, Martina Rosticci, Federica Fogacci, Marina Giovannini, Sergio D'addato, Claudio Borghi
No abstract text is available yet for this article.
August 2017: Atherosclerosis
https://www.readbyqxmd.com/read/29209472/uric-acid-level-has-a-j-shaped-association-with-arterial-stiffness-in-korean-postmenopausal-women
#10
Hyungbin Lee, Young-Hyo Jung, Yu-Jin Kwon, Byoungjin Park
Background: Uric acid has been reported to function both as an oxidant or antioxidant depending on the context. A previous study in the Korean population reported a positive linear association between serum uric acid level and arterial stiffness in men, but little is known about how serum uric acid level is related to the risk of increased arterial stiffness in Korean postmenopausal women. Methods: We performed a cross-sectional study of 293 subjects who participated in a health examination program run by the health promotion center of Gangnam Severance Hospital between October 2007 and July 2010...
November 2017: Korean Journal of Family Medicine
https://www.readbyqxmd.com/read/29171717/sex-related-relationships-between-uric-acid-and-target-organ-damage-in-hypertension
#11
Alessandro Maloberti, Simone Maggioni, Lucia Occhi, Nicola Triglione, Francesco Panzeri, Stefano Nava, Stefano Signorini, Rosanna Falbo, Marco Casati, Guido Grassi, Cristina Giannattasio
Heterogeneous results have been obtained in the relationship between serum uric acid (SUA) and target organ damage (TOD) in patients with hypertension. Clinic blood pressure, SUA, and cardiac, arterial (carotid and aortic), and renal TOD were assessed in 762 consecutive patients with hypertension. Hyperuricemia was defined as an SUA >7.0 in men and >6.0 mg/dL in women. Men with hyperuricemia compared with those with normal SUA showed lower estimated glomerular filtration rates and E/A ratios and a higher prevalence of carotid plaques...
January 2018: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/28904249/relationship-between-serum-uric-acid-and-vascular-function-and-structure-markers-and-gender-difference-in-a-real-world-population-of-china-from-beijing-vascular-disease-patients-evaluation-study-best-study
#12
Huan Liu, Jinbo Liu, Hongwei Zhao, Yingyan Zhou, Lihong Li, Hongyu Wang
AIM: The study was done to establish the relationship between serum uric acid (UA) and vascular function and structure parameters including carotid femoral pulse wave velocity (CF-PWV), carotid radial pulse wave velocity (CR-PWV), cardio ankle vascular index (CAVI), ankle brachial index (ABI), and carotid intima-media thickness (CIMT), and the gender difference in a real-world population from China. METHODS: A total of 979 subjects were enrolled (aged 60.86±11...
March 1, 2018: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/28706180/serum-uric-acid-and-arterial-function-after-renal-transplantation
#13
Frederic Bauer, Nikolaos Pagonas, Felix S Seibert, Walter Zidek, Richard Viebahn, Nina Babel, Timm H Westhoff
BACKGROUND Hyperuricemia is associated with an increased risk of cardiovascular disease and chronic allograft nephropathy after renal transplantation. It has recently been demonstrated that treatment of asymptomatic hyperuricemia is associated with improved patient and graft survival; although, the underlying mechanisms remain elusive. The present study investigated the association of serum uric acid (SUA) and systemic arterial function after renal transplantation. MATERIAL AND METHODS In a cross-sectional study, arterial function was analyzed in 54 renal transplant recipients by means of pulse wave analysis...
July 14, 2017: Annals of Transplantation: Quarterly of the Polish Transplantation Society
https://www.readbyqxmd.com/read/28666027/hyperuricemia-and-risk-of-increased-arterial-stiffness-in-healthy-women-based-on-health-screening-in-korean-population
#14
Hoon Young Choi, Seok-Hyung Kim, Ah Ran Choi, Seung Gyu Kim, Hyunwook Kim, Jung Eun Lee, Hyung Jong Kim, Hyeong Cheon Park
Hyperuricemia is a risk factor for cardiovascular disease and is associated with increased arterial stiffness in high-risk populations. However, given the possible sex-related differences in the prevalence of hyperuricemia, the association between elevated serum uric acid (SUA) level and increased arterial stiffness has yielded conflicting results. We investigated the relationship between SUA and arterial stiffness in asymptomatic healthy subjects who underwent a health examination. Subjects who underwent a comprehensive health examination were enrolled...
2017: PloS One
https://www.readbyqxmd.com/read/28468788/circulating-levels-of-proprotein-convertase-subtilisin-kexin-type-9-and-arterial-stiffness-in-a-large-population-sample-data-from-the-brisighella-heart-study
#15
COMPARATIVE STUDY
Massimiliano Ruscica, Nicola Ferri, Federica Fogacci, Martina Rosticci, Margherita Botta, Silvia Marchiano, Paolo Magni, Sergio D'Addato, Marina Giovannini, Claudio Borghi, Arrigo F G Cicero
BACKGROUND: Proprotein convertase subtilisin/kexin type 9 (PCSK9) circulating levels are significantly associated with an increased risk of cardiovascular events. This study aimed to evaluate the relationship between circulating levels of PCSK9 and arterial stiffness, an early instrumental biomarker of cardiovascular disease risk, in a large sample of overall healthy participants. METHODS AND RESULTS: From the historical cohort of the Brisighella Heart Study, after exclusion of active smokers, participants in secondary prevention for cardiovascular disease, and patients in treatment with statins or vasodilating agents, we selected 227 premenopausal women and 193 age-matched men and 460 postmenopausal women and 416 age-matched men...
May 3, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28437814/assessment-of-early-cardiovascular-risk-in-children-and-adolescents-with-essential-hypertension
#16
Andreja Stelcar, Evgenija Homsak, Natasa Marcun Varda
The aim of our study was to investigate some early markers of hypertensive target organ damage in hypertensive children and adolescents, and to detect those showing most prominent clinical significance. We included 100 children with essential hypertension (EH) and 50 age-matched healthy control children, and evaluated left ventricular mass (LVM), intima-media thickness in the carotid arteries (IMT), pulse wave velocity (PWV), microalbuminuria, biochemical parameters and some adipokines. Statistically significant differences between the 2 groups were observed for HDL-cholesterol, LDL-cholesterol, triglycerides, insulin, uric acid, glucose, apolipoprotein A1, and total adiponectin...
September 2017: Klinische Pädiatrie
https://www.readbyqxmd.com/read/28386182/peripheral-arterial-stiffness-is-associated-with-higher-baseline-plasma-uric-acid-a-prospective-cohort-study
#17
Xiaohan Ding, Ping Ye, Xiaona Wang, Ruihua Cao, Xu Yang, Wenkai Xiao, Yun Zhang, Yongyi Bai, Hongmei Wu
This prospective cohort study aimed at identifying association between uric acid (UA) and peripheral arterial stiffness. A prospective cohort longitudinal study was performed according to an average of 4.8 years' follow-up. The demographic data, anthropometric parameters, peripheral arterial stiffness (carotid-radial pulse-wave velocity, cr-PWV) and biomarker variables including UA were examined at both baseline and follow-up. Pearson's correlations were used to identify the associations between UA and peripheral arterial stiffness...
March 2017: Saudi Journal of Biological Sciences
https://www.readbyqxmd.com/read/28373588/vascular-stiffness-in-children-with-chronic-kidney-disease
#18
Jonathan D Savant, Aisha Betoko, Kevin E C Meyers, Mark Mitsnefes, Joseph T Flynn, Raymond R Townsend, Larry A Greenbaum, Allison Dart, Bradley Warady, Susan L Furth
Carotid-femoral pulse wave velocity (cfPWV) is a measure of arterial stiffness associated with cardiovascular events in the general population and in adults with chronic kidney disease. However, few data exist regarding cfPWV in children with chronic kidney disease. We compared observed cfPWV assessed via applanation tonometry in children enrolled in the CKiD cohort study (Chronic Kidney Disease in Children) to normative data in healthy children and examined risk factors associated with elevated cfPWV. cfPWV Z score for height/gender and age/gender was calculated from and compared with published pediatric norms...
May 2017: Hypertension
https://www.readbyqxmd.com/read/28287880/does-the-serum-uric-acid-level-have-any-relation-to-arterial-stiffness-or-blood-pressure-in-adults-with-congenital-renal-agenesis-and-or-hypoplasia
#19
Raziye Yazici, İbrahim Guney, Lutfullah Altintepe, Mehmet Yazici
BACKGROUND: The relationship between serum uric acid and arterial stiffness or blood pressure is not clear. The serum uric acid level and its association with cardiovascular risk is not well known in patients with reduced renal mass. We aimed to investigate the relation between serum uric acid levels and arterial stiffness and also blood pressure in patients with congenital renal agenesis and/or hypoplasia. MATERIAL AND METHODS: In this single center, cross-sectional study, a total of 55 patients (39 (% 70...
2017: Clinical and Experimental Hypertension: CHE
https://www.readbyqxmd.com/read/28273173/relationships-between-lifestyle-patterns-and-cardio-renal-metabolic-parameters-in-patients-with-type-2-diabetes-mellitus-a-cross-sectional-study
#20
Takeshi Ogihara, Tomoya Mita, Yusuke Osonoi, Takeshi Osonoi, Miyoko Saito, Atsuko Tamasawa, Shiho Nakayama, Yuki Someya, Hidenori Ishida, Masahiko Gosho, Akio Kanazawa, Hirotaka Watada
INTRODUCTION: While individuals tend to show accumulation of certain lifestyle patterns, the effect of such patterns in real daily life on cardio-renal-metabolic parameters remains largely unknown. This study aimed to assess clustering of lifestyle patterns and investigate the relationships between such patterns and cardio-renal-metabolic parameters. PARTICIPANTS AND METHODS: The study participants were 726 Japanese type 2 diabetes mellitus (T2DM) outpatients free of history of cardiovascular diseases...
2017: PloS One
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