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Uric acid AND pulse wave velocity

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https://www.readbyqxmd.com/read/28904249/relationship-between-serum-uric-acid-and-vascular-function-and-structure-markers-and-gender-difference-in-a-real-world-population-of-china-from-beijing-vascular-disease-patients-evaluation-study-best-study
#1
Huan Liu, Jinbo Liu, Hongwei Zhao, Yingyan Zhou, Lihong Li, Hongyu Wang
AIM: The study was done to establish the relationship between serum uric acid (UA) and vascular function and structure parameters including carotid femoral pulse wave velocity (CF-PWV), carotid radial pulse wave velocity (CR-PWV), cardio ankle vascular index (CAVI), ankle brachial index (ABI), and carotid intima-media thickness (CIMT), and the gender difference in a real-world population from China. METHODS: A total of 979 subjects were enrolled (aged 60.86±11...
September 12, 2017: Journal of Atherosclerosis and Thrombosis
https://www.readbyqxmd.com/read/28706180/serum-uric-acid-and-arterial-function-after-renal-transplantation
#2
Frederic Bauer, Nikolaos Pagonas, Felix S Seibert, Walter Zidek, Richard Viebahn, Nina Babel, Timm H Westhoff
BACKGROUND Hyperuricemia is associated with an increased risk of cardiovascular disease and chronic allograft nephropathy after renal transplantation. It has recently been demonstrated that treatment of asymptomatic hyperuricemia is associated with improved patient and graft survival; although, the underlying mechanisms remain elusive. The present study investigated the association of serum uric acid (SUA) and systemic arterial function after renal transplantation. MATERIAL AND METHODS In a cross-sectional study, arterial function was analyzed in 54 renal transplant recipients by means of pulse wave analysis...
July 14, 2017: Annals of Transplantation: Quarterly of the Polish Transplantation Society
https://www.readbyqxmd.com/read/28666027/hyperuricemia-and-risk-of-increased-arterial-stiffness-in-healthy-women-based-on-health-screening-in-korean-population
#3
Hoon Young Choi, Seok-Hyung Kim, Ah Ran Choi, Seung Gyu Kim, Hyunwook Kim, Jung Eun Lee, Hyung Jong Kim, Hyeong Cheon Park
Hyperuricemia is a risk factor for cardiovascular disease and is associated with increased arterial stiffness in high-risk populations. However, given the possible sex-related differences in the prevalence of hyperuricemia, the association between elevated serum uric acid (SUA) level and increased arterial stiffness has yielded conflicting results. We investigated the relationship between SUA and arterial stiffness in asymptomatic healthy subjects who underwent a health examination. Subjects who underwent a comprehensive health examination were enrolled...
2017: PloS One
https://www.readbyqxmd.com/read/28468788/circulating-levels-of-proprotein-convertase-subtilisin-kexin-type-9-and-arterial-stiffness-in-a-large-population-sample-data-from-the-brisighella-heart-study
#4
Massimiliano Ruscica, Nicola Ferri, Federica Fogacci, Martina Rosticci, Margherita Botta, Silvia Marchiano, Paolo Magni, Sergio D'Addato, Marina Giovannini, Claudio Borghi, Arrigo F G Cicero
BACKGROUND: Proprotein convertase subtilisin/kexin type 9 (PCSK9) circulating levels are significantly associated with an increased risk of cardiovascular events. This study aimed to evaluate the relationship between circulating levels of PCSK9 and arterial stiffness, an early instrumental biomarker of cardiovascular disease risk, in a large sample of overall healthy participants. METHODS AND RESULTS: From the historical cohort of the Brisighella Heart Study, after exclusion of active smokers, participants in secondary prevention for cardiovascular disease, and patients in treatment with statins or vasodilating agents, we selected 227 premenopausal women and 193 age-matched men and 460 postmenopausal women and 416 age-matched men...
May 3, 2017: Journal of the American Heart Association
https://www.readbyqxmd.com/read/28437814/assessment-of-early-cardiovascular-risk-in-children-and-adolescents-with-essential-hypertension
#5
Andreja Stelcar, Evgenija Homsak, Natasa Marcun Varda
The aim of our study was to investigate some early markers of hypertensive target organ damage in hypertensive children and adolescents, and to detect those showing most prominent clinical significance. We included 100 children with essential hypertension (EH) and 50 age-matched healthy control children, and evaluated left ventricular mass (LVM), intima-media thickness in the carotid arteries (IMT), pulse wave velocity (PWV), microalbuminuria, biochemical parameters and some adipokines. Statistically significant differences between the 2 groups were observed for HDL-cholesterol, LDL-cholesterol, triglycerides, insulin, uric acid, glucose, apolipoprotein A1, and total adiponectin...
September 2017: Klinische Pädiatrie
https://www.readbyqxmd.com/read/28386182/peripheral-arterial-stiffness-is-associated-with-higher-baseline-plasma-uric-acid-a-prospective-cohort-study
#6
Xiaohan Ding, Ping Ye, Xiaona Wang, Ruihua Cao, Xu Yang, Wenkai Xiao, Yun Zhang, Yongyi Bai, Hongmei Wu
This prospective cohort study aimed at identifying association between uric acid (UA) and peripheral arterial stiffness. A prospective cohort longitudinal study was performed according to an average of 4.8 years' follow-up. The demographic data, anthropometric parameters, peripheral arterial stiffness (carotid-radial pulse-wave velocity, cr-PWV) and biomarker variables including UA were examined at both baseline and follow-up. Pearson's correlations were used to identify the associations between UA and peripheral arterial stiffness...
March 2017: Saudi Journal of Biological Sciences
https://www.readbyqxmd.com/read/28373588/vascular-stiffness-in-children-with-chronic-kidney-disease
#7
Jonathan D Savant, Aisha Betoko, Kevin E C Meyers, Mark Mitsnefes, Joseph T Flynn, Raymond R Townsend, Larry A Greenbaum, Allison Dart, Bradley Warady, Susan L Furth
Carotid-femoral pulse wave velocity (cfPWV) is a measure of arterial stiffness associated with cardiovascular events in the general population and in adults with chronic kidney disease. However, few data exist regarding cfPWV in children with chronic kidney disease. We compared observed cfPWV assessed via applanation tonometry in children enrolled in the CKiD cohort study (Chronic Kidney Disease in Children) to normative data in healthy children and examined risk factors associated with elevated cfPWV. cfPWV Z score for height/gender and age/gender was calculated from and compared with published pediatric norms...
May 2017: Hypertension
https://www.readbyqxmd.com/read/28287880/does-the-serum-uric-acid-level-have-any-relation-to-arterial-stiffness-or-blood-pressure-in-adults-with-congenital-renal-agenesis-and-or-hypoplasia
#8
Raziye Yazici, İbrahim Guney, Lutfullah Altintepe, Mehmet Yazici
BACKGROUND: The relationship between serum uric acid and arterial stiffness or blood pressure is not clear. The serum uric acid level and its association with cardiovascular risk is not well known in patients with reduced renal mass. We aimed to investigate the relation between serum uric acid levels and arterial stiffness and also blood pressure in patients with congenital renal agenesis and/or hypoplasia. MATERIAL AND METHODS: In this single center, cross-sectional study, a total of 55 patients (39 (% 70...
2017: Clinical and Experimental Hypertension: CHE
https://www.readbyqxmd.com/read/28273173/relationships-between-lifestyle-patterns-and-cardio-renal-metabolic-parameters-in-patients-with-type-2-diabetes-mellitus-a-cross-sectional-study
#9
Takeshi Ogihara, Tomoya Mita, Yusuke Osonoi, Takeshi Osonoi, Miyoko Saito, Atsuko Tamasawa, Shiho Nakayama, Yuki Someya, Hidenori Ishida, Masahiko Gosho, Akio Kanazawa, Hirotaka Watada
INTRODUCTION: While individuals tend to show accumulation of certain lifestyle patterns, the effect of such patterns in real daily life on cardio-renal-metabolic parameters remains largely unknown. This study aimed to assess clustering of lifestyle patterns and investigate the relationships between such patterns and cardio-renal-metabolic parameters. PARTICIPANTS AND METHODS: The study participants were 726 Japanese type 2 diabetes mellitus (T2DM) outpatients free of history of cardiovascular diseases...
2017: PloS One
https://www.readbyqxmd.com/read/28270889/relationships-among-conventional-cardiovascular-risk-factors-and-lifestyle-habits-with-arterial-stiffness-in-type-2-diabetic-patients
#10
Misako Hamamura, Tomoya Mita, Yusuke Osonoi, Takeshi Osonoi, Miyoko Saito, Atsuko Tamasawa, Shiho Nakayama, Yuki Someya, Hidenori Ishida, Masahiko Gosho, Akio Kanazawa, Hirotaka Watada
BACKGROUND: While conventional cardiovascular risk factors and certain lifestyle habits are associated with arterial stiffness in patients with type 2 diabetes mellitus (T2DM), it is still unknown whether they are actually associated with arterial stiffness even after adjustment for conventional cardiovascular risk factors and lifestyle habits. The aim of this study was to identify variables that are associated with brachial-ankle pulse wave velocity (baPWV). METHODS: The study participants comprised 724 Japanese T2DM outpatients free of history of cardiovascular diseases...
April 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28202946/association-of-serum-uric-acid-with-subsequent-arterial-stiffness-and-renal-function-in-normotensive-subjects
#11
Shiori Nagano, Maasa Takahashi, Nobuyuki Miyai, Mayumi Oka, Miyoko Utsumi, Mitsuru Shiba, Kanae Mure, Tatsuya Takeshita, Mikio Arita
Serum uric acid (SUA) is correlated with an increased risk of not only gout but also cardiovascular diseases. The present study aimed to longitudinally evaluate the effects of SUA level on renal function and arterial stiffness in a population-based sample of normotensive subjects. The subjects completed a health checkup in 2002 at baseline and in 2011 or 2012 at the end of the follow-up period. A total of 407 normotensive subjects (171 men and 236 women) aged 26-66 years were enrolled in this study. We measured blood pressure (BP), brachial-ankle pulse wave velocity (baPWV), central BP, intima-media thickness, SUA level and estimated glomerular filtration rate (eGFR)...
June 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28178136/a-higher-baseline-plasma-uric-acid-level-is-an-independent-predictor-of-arterial-stiffness-a-community-based-prospective-study
#12
Xiao-Han Ding, Xiaona Wang, Ruihua Cao, Xu Yang, Wenkai Xiao, Yun Zhang, Yongyi Bai, Hongmei Wu, Ping Ye
Hyperuricemia has been demonstrated to be a risk factor for cardiovascular diseases. Though the association between uric acid (UA) and arterial stiffness has been investigated previously in patients with basic diseases, the predictive value of baseline UA level for arterial stiffness has not been conducted. We aimed at identifying the predictive role of UA for arterial stiffness prospectively.A longitudinal follow-up study in a routine health check-up population was performed with an average follow-up of 4...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28098104/evaluation-of-arterial-stiffness-in-nondiabetic-chronic-kidney-disease-patients
#13
Bodanapu Mastanvalli, Kolla Praveen Kumar, Desai Madhav, P L Venkata Pakki Reddy, Shaik Mahaboob Vali
Chronic kidney disease (CKD) is a growing problem worldwide. Clinical and epidemiologic studies have shown that structural and functional changes that occur in major arteries are a major contributing factor to the high mortality in uremic patients. Recent studies have shown a stepwise increase of the carotid-femoral pulse wave velocity (cfPWV) from CKD Stage 1 to Stage 5. We evaluated the cfPWV and augmentation index (AIx), as indirect markers of arterial stiffness in patients with nondiabetic CKD and compared the values with normal population; we also evaluated the relationship between various stages of CKD and arterial stiffness markers...
January 2017: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/28060189/associations-of-risk-factors-in-childhood-with-arterial-stiffness-26-years-later-the-hanzhong-adolescent-hypertension-cohort
#14
Chao Chu, Yi Dai, Jianjun Mu, Ruihai Yang, Man Wang, Jun Yang, Yong Ren, Bingqing Xie, Zhenzhen Dong, Fan Yang, Dan Wang, Dingyi Yan, Tong-Shuai Guo, Yang Wang
OBJECTIVE: The relationship between childhood risk factors and long-term arterial stiffness was explored. METHODS: A baseline survey was conducted in 4623 school children aged 6-15 years in rural areas of Hanzhong city, Shaanxi, in 1987. According to three independent measurements of SBP in 1987, 1989, and 1992, cases of the same age and sex with continuous SBP at least 75 percentile were classified as the high-blood pressure (BP) group, whereas those with SBP less than 50 percentile were classified as the normal-BP group...
May 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28008293/hormonal-and-echocardiographic-abnormalities-in-adult-patients-with-sickle-cell-anemia-in-bahrain
#15
Taysir S Garadah, Ahmed A Jaradat, Mohammed E Alalawi, Adla B Hassan
BACKGROUND: Adrenal, thyroid, and parathyroid gland hormonal changes are recognized in children with homozygous (HbSS) sickle-cell anemia (SCA), but are not clear in adult patients with SCA. AIM: To assess the metabolic and endocrine abnormalities in adult patients with SCA and evaluate left ventricular (LV) systolic and diastolic functions compared with patients with no SCA and further study the relationship between serum levels of cortisol, free thyroxine (T4), and testosterone with serum ferritin...
2016: Journal of Blood Medicine
https://www.readbyqxmd.com/read/27956574/longitudinal-association-between-serum-uric-acid-and-arterial-stiffness-results-from-the-baltimore-longitudinal-study-of-aging
#16
Marco Canepa, Francesca Viazzi, James B Strait, Pietro Ameri, Roberto Pontremoli, Claudio Brunelli, Stephanie Studenski, Luigi Ferrucci, Edward G Lakatta, Majd AlGhatrif
Serum uric acid (SUA) has long been associated with increased cardiovascular risk, with arterial stiffness proposed as a mediator. However, evidence on the association between SUA and arterial stiffness is limited to contradicting cross-sectional studies. In this analysis, we examined the longitudinal relationship between SUA and pulse wave velocity, a measure of arterial stiffness, in a community-dwelling population. We studied 446 women and 427 men participating in the BLSA (Baltimore Longitudinal Study of Aging), with 1409 and 1434 observations, respectively, over an average period of 6 years...
February 2017: Hypertension
https://www.readbyqxmd.com/read/27754036/os-13-02-association-between-uric-acid-metabolic-variables-and-arterial-stiffness-in-the-early-phase-of-hypertension
#17
Francesca Saladini, Elisabetta Benetti, Claudio Fania, Lucio Mos, Raffaella Garbelotto, Andrea Mazzer, Edoardo Casiglia, Paolo Palatini
OBJECTIVE: High serum uric acid (SUA) is often associated with the metabolic syndrome and is a risk factor for cardiovascular disease. Whether high SUA is associated with arterial stiffness in the early stage of hypertension is not well known. DESIGN AND METHOD: We addressed this issue in 340 non-diabetic subjects from the HARVEST study (73% males) with a mean age of 31 ± 8 years and a mean blood pressure (BP) of 145 ± 11/92 ± 6 mmHg. Patients were divided into SUA tertiles (T1: 1...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27753924/os-04-08-the-relationship-between-childhood-risk-factors-and-long-term-arterial-stiffness-a-26-year-follow-up-study
#18
Jianjun Mu, Chao Chu, Dan Wang, Tongshuai Guo, Yang Wang, Fan Yang
OBJECTIVE: To explore the relationship between childhood risk factors and long-term arterial stiffness. DESIGN AND METHOD: A baseline survey was carried out in 4623 school children aged 6-15 years in rural areas of Hanzhong city, Shaanxi in 1987. According to three measurements of systolic blood pressure (SBP) in 1987,1989 and 1992, high blood pressure group (HBP group) was defined as SBP ≥ 75 percentile at same age and gender, with SBP < 50 percentile as normal blood pressure group (NBP group)...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27676633/relationship-between-equol-producer-status-and-metabolic-parameters-in-743-japanese-women-equol-producer-status-is-associated-with-antiatherosclerotic-conditions-in-women-around-menopause-and-early-postmenopause
#19
Remi Yoshikata, Khin Z Myint, Hiroaki Ohta
OBJECTIVE: Equol, an active metabolite possessing estrogen-like activity, is produced by the action of intestinal flora on soy isoflavones. There is an increasing evidence regarding its efficacy in the relief of menopausal symptoms, suppression of decreased bone mineral density, and lipid profile improvement. Only those with equol-producing capacity, however, seem to benefit. Thus, we examined the relationship between equol producer status and parameters associated with lifestyle-related diseases in women from their 20s to 80s...
February 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/27643317/os-04-08-the-relationship-between-childhood-risk-factors-and-long-term-arterial-stiffness-a-26-year-follow-up-study
#20
Jianjun Mu, Chao Chu, Dan Wang, Tongshuai Guo, Yang Wang, Fan Yang
OBJECTIVE: To explore the relationship between childhood risk factors and long-term arterial stiffness. DESIGN AND METHOD: A baseline survey was carried out in 4623 school children aged 6-15 years in rural areas of Hanzhong city, Shaanxi in 1987. According to three measurements of systolic blood pressure (SBP) in 1987,1989 and 1992, high blood pressure group (HBP group) was defined as SBP ≥ 75 percentile at same age and gender, with SBP < 50 percentile as normal blood pressure group (NBP group)...
September 2016: Journal of Hypertension
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