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Uric acid AND pulse wave velocity

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https://www.readbyqxmd.com/read/28287880/does-the-serum-uric-acid-level-have-any-relation-to-arterial-stiffness-or-blood-pressure-in-adults-with-congenital-renal-agenesis-and-or-hypoplasia
#1
Raziye Yazici, İbrahim Guney, Lutfullah Altintepe, Mehmet Yazici
BACKGROUND: The relationship between serum uric acid and arterial stiffness or blood pressure is not clear. The serum uric acid level and its association with cardiovascular risk is not well known in patients with reduced renal mass. We aimed to investigate the relation between serum uric acid levels and arterial stiffness and also blood pressure in patients with congenital renal agenesis and/or hypoplasia. MATERIAL AND METHODS: In this single center, cross-sectional study, a total of 55 patients (39 (% 70...
2017: Clinical and Experimental Hypertension: CHE
https://www.readbyqxmd.com/read/28273173/relationships-between-lifestyle-patterns-and-cardio-renal-metabolic-parameters-in-patients-with-type-2-diabetes-mellitus-a-cross-sectional-study
#2
Takeshi Ogihara, Tomoya Mita, Yusuke Osonoi, Takeshi Osonoi, Miyoko Saito, Atsuko Tamasawa, Shiho Nakayama, Yuki Someya, Hidenori Ishida, Masahiko Gosho, Akio Kanazawa, Hirotaka Watada
INTRODUCTION: While individuals tend to show accumulation of certain lifestyle patterns, the effect of such patterns in real daily life on cardio-renal-metabolic parameters remains largely unknown. This study aimed to assess clustering of lifestyle patterns and investigate the relationships between such patterns and cardio-renal-metabolic parameters. PARTICIPANTS AND METHODS: The study participants were 726 Japanese type 2 diabetes mellitus (T2DM) outpatients free of history of cardiovascular diseases...
2017: PloS One
https://www.readbyqxmd.com/read/28270889/relationships-among-conventional-cardiovascular-risk-factors-and-lifestyle-habits-with-arterial-stiffness-in-type-2-diabetic-patients
#3
Misako Hamamura, Tomoya Mita, Yusuke Osonoi, Takeshi Osonoi, Miyoko Saito, Atsuko Tamasawa, Shiho Nakayama, Yuki Someya, Hidenori Ishida, Masahiko Gosho, Akio Kanazawa, Hirotaka Watada
BACKGROUND: While conventional cardiovascular risk factors and certain lifestyle habits are associated with arterial stiffness in patients with type 2 diabetes mellitus (T2DM), it is still unknown whether they are actually associated with arterial stiffness even after adjustment for conventional cardiovascular risk factors and lifestyle habits. The aim of this study was to identify variables that are associated with brachial-ankle pulse wave velocity (baPWV). METHODS: The study participants comprised 724 Japanese T2DM outpatients free of history of cardiovascular diseases...
April 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28202946/association-of-serum-uric-acid-with-subsequent-arterial-stiffness-and-renal-function-in-normotensive-subjects
#4
Shiori Nagano, Maasa Takahashi, Nobuyuki Miyai, Mayumi Oka, Miyoko Utsumi, Mitsuru Shiba, Kanae Mure, Tatsuya Takeshita, Mikio Arita
Serum uric acid (SUA) is correlated with an increased risk of not only gout but also cardiovascular diseases. The present study aimed to longitudinally evaluate the effects of SUA level on renal function and arterial stiffness in a population-based sample of normotensive subjects. The subjects completed a health checkup in 2002 at baseline and in 2011 or 2012 at the end of the follow-up period. A total of 407 normotensive subjects (171 men and 236 women) aged 26-66 years were enrolled in this study. We measured blood pressure (BP), brachial-ankle pulse wave velocity (baPWV), central BP, intima-media thickness, SUA level and estimated glomerular filtration rate (eGFR)...
February 16, 2017: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/28178136/a-higher-baseline-plasma-uric-acid-level-is-an-independent-predictor-of-arterial-stiffness-a-community-based-prospective-study
#5
Xiao-Han Ding, Xiaona Wang, Ruihua Cao, Xu Yang, Wenkai Xiao, Yun Zhang, Yongyi Bai, Hongmei Wu, Ping Ye
Hyperuricemia has been demonstrated to be a risk factor for cardiovascular diseases. Though the association between uric acid (UA) and arterial stiffness has been investigated previously in patients with basic diseases, the predictive value of baseline UA level for arterial stiffness has not been conducted. We aimed at identifying the predictive role of UA for arterial stiffness prospectively.A longitudinal follow-up study in a routine health check-up population was performed with an average follow-up of 4...
February 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28098104/evaluation-of-arterial-stiffness-in-nondiabetic-chronic-kidney-disease-patients
#6
Bodanapu Mastanvalli, Kolla Praveen Kumar, Desai Madhav, P L Venkata Pakki Reddy, Shaik Mahaboob Vali
Chronic kidney disease (CKD) is a growing problem worldwide. Clinical and epidemiologic studies have shown that structural and functional changes that occur in major arteries are a major contributing factor to the high mortality in uremic patients. Recent studies have shown a stepwise increase of the carotid-femoral pulse wave velocity (cfPWV) from CKD Stage 1 to Stage 5. We evaluated the cfPWV and augmentation index (AIx), as indirect markers of arterial stiffness in patients with nondiabetic CKD and compared the values with normal population; we also evaluated the relationship between various stages of CKD and arterial stiffness markers...
January 2017: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/28060189/associations-of-risk-factors-in-childhood-with-arterial-stiffness-26-years-later-the-hanzhong-adolescent-hypertension-cohort
#7
Chao Chu, Yi Dai, Jianjun Mu, Ruihai Yang, Man Wang, Jun Yang, Yong Ren, Bingqing Xie, Zhenzhen Dong, Fan Yang, Dan Wang, Dingyi Yan, Tong-Shuai Guo, Yang Wang
OBJECTIVE: The relationship between childhood risk factors and long-term arterial stiffness was explored. METHODS: A baseline survey was conducted in 4623 school children aged 6-15 years in rural areas of Hanzhong city, Shaanxi, in 1987. According to three independent measurements of SBP in 1987, 1989, and 1992, cases of the same age and sex with continuous SBP at least 75 percentile were classified as the high-blood pressure (BP) group, whereas those with SBP less than 50 percentile were classified as the normal-BP group...
January 5, 2017: Journal of Hypertension
https://www.readbyqxmd.com/read/28008293/hormonal-and-echocardiographic-abnormalities-in-adult-patients-with-sickle-cell-anemia-in-bahrain
#8
Taysir S Garadah, Ahmed A Jaradat, Mohammed E Alalawi, Adla B Hassan
BACKGROUND: Adrenal, thyroid, and parathyroid gland hormonal changes are recognized in children with homozygous (HbSS) sickle-cell anemia (SCA), but are not clear in adult patients with SCA. AIM: To assess the metabolic and endocrine abnormalities in adult patients with SCA and evaluate left ventricular (LV) systolic and diastolic functions compared with patients with no SCA and further study the relationship between serum levels of cortisol, free thyroxine (T4), and testosterone with serum ferritin...
2016: Journal of Blood Medicine
https://www.readbyqxmd.com/read/27956574/longitudinal-association-between-serum-uric-acid-and-arterial-stiffness-results-from-the-baltimore-longitudinal-study-of-aging
#9
Marco Canepa, Francesca Viazzi, James B Strait, Pietro Ameri, Roberto Pontremoli, Claudio Brunelli, Stephanie Studenski, Luigi Ferrucci, Edward G Lakatta, Majd AlGhatrif
Serum uric acid (SUA) has long been associated with increased cardiovascular risk, with arterial stiffness proposed as a mediator. However, evidence on the association between SUA and arterial stiffness is limited to contradicting cross-sectional studies. In this analysis, we examined the longitudinal relationship between SUA and pulse wave velocity, a measure of arterial stiffness, in a community-dwelling population. We studied 446 women and 427 men participating in the BLSA (Baltimore Longitudinal Study of Aging), with 1409 and 1434 observations, respectively, over an average period of 6 years...
February 2017: Hypertension
https://www.readbyqxmd.com/read/27754036/os-13-02-association-between-uric-acid-metabolic-variables-and-arterial-stiffness-in-the-early-phase-of-hypertension
#10
Francesca Saladini, Elisabetta Benetti, Claudio Fania, Lucio Mos, Raffaella Garbelotto, Andrea Mazzer, Edoardo Casiglia, Paolo Palatini
OBJECTIVE: High serum uric acid (SUA) is often associated with the metabolic syndrome and is a risk factor for cardiovascular disease. Whether high SUA is associated with arterial stiffness in the early stage of hypertension is not well known. DESIGN AND METHOD: We addressed this issue in 340 non-diabetic subjects from the HARVEST study (73% males) with a mean age of 31 ± 8 years and a mean blood pressure (BP) of 145 ± 11/92 ± 6 mmHg. Patients were divided into SUA tertiles (T1: 1...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27753924/os-04-08-the-relationship-between-childhood-risk-factors-and-long-term-arterial-stiffness-a-26-year-follow-up-study
#11
Jianjun Mu, Chao Chu, Dan Wang, Tongshuai Guo, Yang Wang, Fan Yang
OBJECTIVE: To explore the relationship between childhood risk factors and long-term arterial stiffness. DESIGN AND METHOD: A baseline survey was carried out in 4623 school children aged 6-15 years in rural areas of Hanzhong city, Shaanxi in 1987. According to three measurements of systolic blood pressure (SBP) in 1987,1989 and 1992, high blood pressure group (HBP group) was defined as SBP ≥ 75 percentile at same age and gender, with SBP < 50 percentile as normal blood pressure group (NBP group)...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27676633/relationship-between-equol-producer-status-and-metabolic-parameters-in-743-japanese-women-equol-producer-status-is-associated-with-antiatherosclerotic-conditions-in-women-around-menopause-and-early-postmenopause
#12
Remi Yoshikata, Khin Z Myint, Hiroaki Ohta
OBJECTIVE: Equol, an active metabolite possessing estrogen-like activity, is produced by the action of intestinal flora on soy isoflavones. There is an increasing evidence regarding its efficacy in the relief of menopausal symptoms, suppression of decreased bone mineral density, and lipid profile improvement. Only those with equol-producing capacity, however, seem to benefit. Thus, we examined the relationship between equol producer status and parameters associated with lifestyle-related diseases in women from their 20s to 80s...
February 2017: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/27643317/os-04-08-the-relationship-between-childhood-risk-factors-and-long-term-arterial-stiffness-a-26-year-follow-up-study
#13
Jianjun Mu, Chao Chu, Dan Wang, Tongshuai Guo, Yang Wang, Fan Yang
OBJECTIVE: To explore the relationship between childhood risk factors and long-term arterial stiffness. DESIGN AND METHOD: A baseline survey was carried out in 4623 school children aged 6-15 years in rural areas of Hanzhong city, Shaanxi in 1987. According to three measurements of systolic blood pressure (SBP) in 1987,1989 and 1992, high blood pressure group (HBP group) was defined as SBP ≥ 75 percentile at same age and gender, with SBP < 50 percentile as normal blood pressure group (NBP group)...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27642954/os-13-02-association-between-uric-acid-metabolic-variables-and-arterial-stiffness-in-the-early-phase-of-hypertension
#14
Francesca Saladini, Elisabetta Benetti, Claudio Fania, Lucio Mos, Raffaella Garbelotto, Andrea Mazzer, Edoardo Casiglia, Paolo Palatini
OBJECTIVE: High serum uric acid (SUA) is often associated with the metabolic syndrome and is a risk factor for cardiovascular disease. Whether high SUA is associated with arterial stiffness in the early stage of hypertension is not well known. DESIGN AND METHOD: We addressed this issue in 340 non-diabetic subjects from the HARVEST study (73% males) with a mean age of 31 ± 8 years and a mean blood pressure (BP) of 145 ± 11/92 ± 6 mmHg. Patients were divided into SUA tertiles (T1: 1...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27508719/-op-1b-03-identification-of-a-cut-off-level-of-uric-acid-associated-with-vascular-stiffness-in-a-general-population
#15
A Di Leva, M Koretzky, S Obregon, P Pardini, G Maccallini, M Haehnel, E Huguet, F Botto, A Scuteri, P M Nilsson, C Kotliar
OBJECTIVE: The role of uric acid (UA) in the development of hypertension and atherosclerosis has been extensively studied. In regard to vascular stiffness, UA has demonstrated an independent association with age, gender, obesity, blood pressure and renal function. However, research has focused on the relationship between UA elevation and high blood pressure or atherosclerosis in hypertensive and renal failure patients. Recent data from the Framingham cohort, showed that this association persists in the general population...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27498274/high-serum-uric-acid-is-associated-to-poorly-controlled-blood-pressure-and-higher-arterial-stiffness-in-hypertensive-subjects
#16
Arrigo F G Cicero, Martina Rosticci, Federica Fogacci, Elisa Grandi, Sergio D'Addato, Claudio Borghi
INTRODUCTION: Serum uric acid (SUA) has been associated to incident hypertension and increased risk of cardiovascular diseases. MATERIALS AND METHODS: Among the 2191 subjects enrolled during the last population survey of the Brisighella Heart Study, we identified 146 new cases of arterial hypertension and 394 treated but uncontrolled hypertensive patients with different levels of SUA. Their hemodynamic characteristics have been compared with those of age- and sex-matched normotensive (N...
January 2017: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/27371101/correlations-of-nonalcoholic-fatty-liver-disease-and-serum-uric-acid-with-subclinical-atherosclerosis-in-obese-chinese-adults
#17
Yongwen Liu, Changqin Liu, Xiulin Shi, Mingzhu Lin, Bing Yan, Xin Zeng, Ningning Chen, Shuhua Lu, Suhuan Liu, Shuyu Yang, Xuejun Li, Zhibin Li
BACKGROUND: Existing evidence about the associations of nonalcoholic fatty liver disease (NAFLD) and serum uric acid (SUA) with subclinical atherosclerosis is controversial. The present study aimed to examine the associations of NAFLD and SUA with subclinical atherosclerosis. METHODS: A cross-sectional study of 1,354 obese adults underwent hepatic ultrasonography scanning and arteriosclerosis detection was conducted in Xiamen, China. Subclinical atherosclerosis indices were brachial-ankle pulse wave velocity (ba-PWV) and ankle-brachial index (ABI)...
July 1, 2016: Journal of Diabetes
https://www.readbyqxmd.com/read/27295214/potential-role-of-vegetarianism-on-nutritional-and-cardiovascular-status-in-taiwanese-dialysis-patients-a-case-control-study
#18
Shih-Hsiang Ou, Mei-Yin Chen, Chien-Wei Huang, Nai-Ching Chen, Chien-Hsing Wu, Chih-Yang Hsu, Kang-Ju Chou, Po-Tsang Lee, Hua-Chang Fang, Chien-Liang Chen
BACKGROUND & OBJECTIVES: Cardiovascular disease remains the most common cause of death for patients on chronic dialysis. End stage renal disease patients undergoing dialysis imposed to reduce phosphorus intake, which likely contributes to development of vegetarian diet behaviors. Vegetarian diets are often lower in protein content, in contradiction to the recommendation that a high protein diet is followed by patients undergoing dialysis. The purpose of the study was to investigate the effects of a vegetarian diet on the nutritional and cardiovascular status of dialysis patients...
2016: PloS One
https://www.readbyqxmd.com/read/27247108/association-between-uric-acid-and-renal-function-in-hypertensive-patients-which-role-for-systemic-vascular-involvement
#19
Giulio Geraci, Giuseppe Mulè, Massimiliano Morreale, Claudia Cusumano, Antonella Castiglia, Francesca Gervasi, Francesco D'Ignoto, Manuela Mogavero, Calogero Geraci, Santina Cottone
The role of systemic vascular involvement in mediating the association between serum uric acid (SUA) and renal function in hypertension has not been explored. Main purpose of our study was to investigate whether morphofunctional vascular changes, assessed as carotid intima-media thickness (cIMT) and aortic pulse wave velocity (aPWV), might mediate the association between SUA and renal damage. We enrolled 523 hypertensive subjects with or without chronic kidney disease and divided population into tertiles of SUA based on sex-specific cutoff values...
July 2016: Journal of the American Society of Hypertension: JASH
https://www.readbyqxmd.com/read/27239926/-peripheral-vessel-wall-changes-in-hypertensive-patients-with-gout
#20
B A Shelest
AIM: To investigate the specific features of arterial wall endothelial dysfunction and stiffness in patients with hypertension concurrent with gout. SUBJECTS AND METHODS: A total of 54 patients were examined and divided into 2 groups. A study group consisted of 33 hypertensive patients with gout and a comparison group included 21 hypertensive patients without hyperuricemia. The patients did not differ in blood pressure (BP) readings. Uric acid was determined by the reaction with tungstophosphoric solution AT (Reagent, Dnepropetrovsk, Ukraine)...
2016: Terapevticheskiĭ Arkhiv
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