keyword
MENU ▼
Read by QxMD icon Read
search

velocity

keyword
https://www.readbyqxmd.com/read/28342974/after-total-knee-replacement-younger-patients-demonstrate-superior-balance-control-compared-to-older-patients-when-recovering-from-a-forward-fall
#1
Brian D Street, William Gage
BACKGROUND: National joint replacement registries have reported a substantial growth in younger knee osteoarthritic patients (<55years old) undergoing total knee replacement, however this younger population is generally understudied. Importantly, studies examining experimentally controlled perturbation have shown age-related differences between younger and older healthy adults, whether similar age-related differences exist among total knee replacement patients is unknown. METHODS: A total of 59 participants, including 29 unilateral total knee replacement patients (six-months post-surgery) made up the four experimental groups: 1) younger patient (54...
March 16, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/28342788/analytical-ultracentrifugation-for-analysis-of-doxorubicin-loaded-liposomes
#2
Dora Mehn, Patrizia Iavicoli, Noelia Cabaleiro, Sven Even Borgos, Fanny Caputo, Otmar Geiss, Luigi Calzolai, François Rossi, Douglas Gilliland
Analytical ultracentrifugation (AUC) is a powerful tool for the study of particle size distributions and interactions with high accuracy and resolution. In this work, we show how the analysis of sedimentation velocity data from the AUC can be used to characterize nanocarrier drug delivery systems used in nanomedicine. Nanocarrier size distribution and the ratio of free versus nanoparticle-encapsulated drug in a commercially available liposomal doxorubicin formulation are determined using interference and absorbance based AUC measurements and compared with results generated with conventional techniques...
March 22, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28342735/inhibition-of-effector-antigen-specific-t-cells-by-intradermal-administration-of-heme-oxygenase-1-inducers
#3
Thomas Simon, Julien Pogu, Séverine Rémy, Frédéric Brau, Sylvie Pogu, Maud Maquigneau, Jean-François Fonteneau, Nicolas Poirier, Bernard Vanhove, Gilles Blancho, Eliane Piaggio, Ignacio Anegon, Philippe Blancou
Developing protocols aimed at inhibiting effector T cells would be key for the treatment of T cell-dependent autoimmune diseases including type 1 autoimmune diabetes (T1D) and multiple sclerosis (MS). While heme oxygenase-1 (HO-1) inducers are clinically approved drugs for non-immune-related diseases, they do have immunosuppressive properties when administered systemically in rodents. Here we show that HO-1 inducers inhibit antigen-specific effector T cells when injected intradermally together with the T cell cognate antigens in mice...
March 22, 2017: Journal of Autoimmunity
https://www.readbyqxmd.com/read/28342532/shear-scaling-based-approach-for-irreversible-energy-loss-estimation-in-stenotic-aortic-flow-an-in-vitro-study
#4
Utku Gülan, Christian Binter, Sebastian Kozerke, Markus Holzner
Today, the functional and risk assessment of stenosed arteries is mostly based on ultrasound Doppler blood flow velocity measurements or catheter pressure measurements, which rely on several assumptions. Alternatively, blood velocity including turbulent kinetic energy (TKE) may be measured using MRI. The aim of the present study is to validate a TKE-based approach that relies on the fact that turbulence production is dominated by the flow's shear to determine the total irreversible energy loss from MRI scans...
March 12, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28342520/duplex-velocity-criteria-for-carotid-endarterectomy
#5
EDITORIAL
Thomas G Brott, James F Meschia, Brajesh K Lal
No abstract text is available yet for this article.
April 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/28342360/ensemble-based-release-estimation-for-accidental-river-pollution-with-known-source-position
#6
Xiaole Zhang, Meng Huang
Dispersion model is an important tool for decision makers to accurately assess risks and effectively plan countermeasures during river pollution accidents, but their applications suffer from significant modeling uncertainties, primarily due to the scarce information of the source. A fully sequential inverse estimation method is proposed to reconstruct the temporal release for accidental river pollution. The method is based on a one-dimensional advection-dispersion model in conjunction with the augmented ensemble Kalman filter method...
March 15, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28340403/micro-and-macrovascular-function-in-children-with-sickle-cell-anaemia-and-sickle-cell-haemoglobin-c-disease
#7
Berenike Möckesch, Keyne Charlot, Stéphane Jumet, Marc Romana, Lydia Divialle-Doumdo, Marie-Dominique Hardy-Dessources, Marie Petras, Benoît Tressieres, Vanessa Tarer, Olivier Hue, Maryse Etienne-Julan, Philippe Connes, Sophie Antoine-Jonville
It is unclear whether vascular function is affected similarly in children with sickle cell anaemia (SS) and children with sickle haemoglobin C (SC) disease. Therefore, we compared micro and macrovascular functions in healthy (AA) children, children with SS and SC disease, and assessed their association with physical activity. Participants (24 SS, 22 SC and 16 AA), were compared in terms of 1) thermal hyperaemic response (finger pad warming to 42°C) measured by Laser Doppler techniques, 2) arterial stiffness determined by pulse wave velocity, 3) daily energy expenditure related to moderate and intense physical activities estimated by questionnaire and 4) fitness level, evaluated by the six-minute walk test...
February 4, 2017: Blood Cells, Molecules & Diseases
https://www.readbyqxmd.com/read/28340296/ultra-low-surface-recombination-velocity-in-passivated-ingaas-inp-nanopillars
#8
Aura Higuera-Rodriguez, Bruno Romeira, Simone Birindelli, Lachlan E Black, Barry Smalbrugge, Peter J van Veldhoven, Wilhelmus Erwin M M Kessels, Meint K Smit, Andrea Fiore
The III-V semiconductor InGaAs is a key material for photonics since it provides optical emission and absorption in the 1.55 μm telecommunication wavelength window. However, InGaAs suffers from pronounced non-radiative effects associated with its surface states, which affect the performance of nanophotonic devices for optical interconnects, namely nanolasers and nanodetectors. This work reports the strong suppression of surface recombination of undoped InGaAs/InP nanostructured semiconductor pillars using a combination of ammonium sulfide, (NH4)2S, passivation and silicon oxide, SiOx, coating...
March 24, 2017: Nano Letters
https://www.readbyqxmd.com/read/28340177/the-significance-of-internode-length-for-saltatory-conduction-looking-back-at-the-age-of-90
#9
Reinhard L Friede
The development of peripheral nerve fibers involves interdependence between the timing of Schwann cell recruitment during myelination and elongation of the nerve. This adjusts the number and the length of internodes to the length of the fiber. Saltatory conduction in longer nerves involves longer saltations; this makes internode length the factor that determines conduction velocity, thereby adjusting impulse transmission in circuits of different lengths. Myelination increases conduction velocity by means of saltatory conduction but what determines the saltatory conduction is not so much the indispensable insulating adjunct of myelin as the length of the internodes that separate the excitable membrane segments...
March 14, 2017: Journal of Neuropathology and Experimental Neurology
https://www.readbyqxmd.com/read/28339733/a-two-phase-mixture-model-of-platelet-aggregation
#10
Jian Du, Aaron L Fogelson
We present a two-phase model of platelet aggregation in coronary-artery-sized blood vessels. The model tracks the number densities of three platelet populations as well as the concentration of a platelet activating chemical. Through the formation of elastic bonds, activated platelets can cohere with one another to form a platelet thrombus. Bound platelets in a thrombus move in a velocity field different from that of the bulk fluid. Stresses produced by the elastic bonds act on the bound platelet material. Movement of the bound platelet material and that of the background fluid are coupled through an interphase drag and an incompressibility constraint...
February 20, 2017: Mathematical Medicine and Biology: a Journal of the IMA
https://www.readbyqxmd.com/read/28339694/regional-acidosis-locally-inhibits-but-remotely-stimulates-ca2-waves-in-ventricular-myocytes
#11
Kerrie L Ford, Emma L Moorhouse, Mario Bortolozzi, Mark Richards, Pawel Swietach, Richard D Vaughan-Jones
AIMS: Spontaneous Ca2+ waves in cardiomyocytes are potentially arrhythmogenic. A powerful controller of Ca2+ waves is the cytoplasmic H+ concentration ([H+]i), which fluctuates spatially and temporally in conditions such as myocardial ischaemia/reperfusion. H+-control of Ca2+ waves is poorly understood. We have therefore investigated how [H+]i co-ordinates their initiation and frequency. METHODS AND RESULTS: Spontaneous Ca2+ waves were imaged (fluo-3) in rat isolated ventricular myocytes, subjected to modest Ca2+-overload...
February 21, 2017: Cardiovascular Research
https://www.readbyqxmd.com/read/28339490/create-your-own-stimulus-manipulating-movements-according-to-social-categories
#12
Markus Koppensteiner, Georg Primes, Pia Stephan
People ascribe purposeful behaviour to the movements of artificial objects and social qualities to human body motion. We investigated how people associate simple motion cues with social categories. For a first rating-experiment we converted the body movements of speakers into stick-figure animations; for a second rating-experiment we used animations of one single dot. Rating-experiments were "reversed" because we asked participants to alter the movements (i.e., vertical amplitude, horizontal amplitude, and velocity) of the stimuli according to different instructions (e...
2017: PloS One
https://www.readbyqxmd.com/read/28339483/temporal-evolution-of-vasospasm-and-clinical-outcome-after-intra-arterial-vasodilator-therapy-in-patients-with-aneurysmal-subarachnoid-hemorrhage
#13
Laleh Daftari Besheli, Can Ozan Tan, Donnie L Bell, Joshua A Hirsch, Rajiv Gupta
Intra-arterial (IA) vasodilator therapy is one of the recommended treatments to minimize the impact of aneurysmal subarachnoid hemorrhage-induced cerebral vasospasm refractory to standard management. However, its usefulness and efficacy is not well established. We evaluated the effect IA vasodilator therapy on middle cerebral artery blood flow and on discharge outcome. We reviewed records for 115 adults admitted to Neurointensive Care Unit to test whether there was a difference in clinical outcome (discharge mRS) in those who received IA infusions...
2017: PloS One
https://www.readbyqxmd.com/read/28339350/the-effect-of-initial-knee-angle-on-concentric-only-squat-jump-performance
#14
Lachlan J Mitchell, Christos K Argus, Kristie-Lee Taylor, Jeremy M Sheppard, Dale W Chapman
PURPOSE: There is uncertainty as to which knee angle during a squat jump (SJ) produces maximal jump performance. Importantly, understanding this information will aid in determining appropriate ratios for assessment and monitoring of the explosive characteristics of athletes. METHOD: This study compared SJ performance across different knee angles-90º, 100º, 110º, 120º, 130º, and a self-selected depth-for jump height and other kinetic characteristics. For comparison between SJ and an unconstrained dynamic movement, participants also performed a countermovement jump from a self-selected depth...
March 24, 2017: Research Quarterly for Exercise and Sport
https://www.readbyqxmd.com/read/28339088/sclerostin-is-a-possible-candidate-marker-of-arterial-stiffness-results-from-a-cohort-study-in-catania
#15
Agostino Gaudio, Valerio Fiore, Rosario Rapisarda, Maria Helga Sidoti, Anastasia Xourafa, Antonino Catalano, Giovanni Tringali, Luca Zanoli, Salvatore Santo Signorelli, Carmelo Erio Fiore
Osteoporosis and cardiovascular disease are worldwide public health issues. Recent evidence indicates a possible role of the canonical Wnt/β-catenin signalling pathway as a common mediator between these two diseases. The aim of the present study was to investigate the relationship between serum concentrations of sclerostin and Dkk1, two extracellular inhibitors of Wnt/β-catenin signalling, with carotid intima-media thickness (CIMT) and with arterial stiffness, evaluated by measuring the pulse wave velocity (PWV) in an ambulatory population of adults...
March 24, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28339044/suppression-of-nuclear-factor-erythroid%C3%A2-2%C3%A2-related-factor-2%C3%A2-mediated-antioxidative-defense-in-the-lung-injury-induced-by-chronic-exposure-to-methamphetamine-in-rats
#16
Yang Bai, Yun Wang, Ming Liu, Yu-Han Gu, Bin Jiang, Xu Wu, Huai-Liang Wang
The imbalance between oxidative stress and antioxidant defense is important in the pathogenesis of lung diseases. Nuclear factor erythroid‑2‑related factor 2 (Nrf2) is a key transcriptional factor that regulates the antioxidant response. The purpose of the present study was to investigate whether Nrf2‑mediated antioxidative defense is involved in methamphetamine (MA)‑induced lung injury in rats. Following establishment of chronic MA toxicity in rats, Doppler ultrasonic detection was used to measure the changes of physiological indexes, followed by hematoxylin and eosin staining, ELISA and western blot analysis...
March 22, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28338799/novel-form-of-the-michaelis-menten-equation-that-enables-accurate-estimation-of-kcat-km-ki-with-just-two-rate-measurements-utility-in-directed-evolution
#17
Jian Lu, Yuxia Dong, Emily C Ng, Daniel L Siehl
One of applications of directed evolution is to desensitize an enzyme to an inhibitor. kcat,1/KM and KI are three dimensions that when multiplied measure an enzyme's intrinsic capacity for catalysis in the presence of an inhibitor. The ideal values for the individual dimensions depend on substrate and inhibitor concentrations under the conditions of the application. When attempting to optimize those values by directed evolution, (kcat/KM)*KI can be an informative parameter for evaluating libraries of variants, but throughput is limited...
February 22, 2017: Protein Engineering, Design & Selection: PEDS
https://www.readbyqxmd.com/read/28338761/influence-of-polynucleosome-preparation-methods-on-sedimentation-velocity-analysis-of-chromatin
#18
Tomoya Kujirai, Shinichi Machida, Akihisa Osakabe, Hitoshi Kurumizaka
Chromatin dynamics and higher order structures play essential roles in genomic DNA functions. Histone variants and histone post-translational modifications are involved in the regulation of chromatin structure and dynamics, cooperatively with DNA methylation and chromatin binding proteins. Therefore, studies of higher-order chromatin conformations have become important to reveal how genomic DNA is regulated during DNA transcription, replication, recombination and repair. The sedimentation velocity analysis by analytical ultracentrifugation has been commonly used to evaluate the higher-order conformation of in vitro reconstituted polynucleosomes, as model chromatin...
December 22, 2016: Journal of Biochemistry
https://www.readbyqxmd.com/read/28338528/perceptual-mechanical-and-electromyographic-responses-to-different-relative-loads-in-the-parallel-squat
#19
Mark Chapman, Eneko Larumbe-Zabala, Mark Gosss-Sampson, Mark Colpus, N Travis Triplett, Fernando Naclerio
The effectiveness of the OMNI-RES (0-10) and the electromyographic signal for monitoring changes in the movement velocity was examined during a set to muscular failure using different percentages of one repetition maximum (1RM) in the parallel squat exercise (PSQ). Twelve males (26.3 ± 5.8 years) were evaluated on eight separate days with 48 hours of rest between sessions. After determining the 1RM value, participants underwent seven tests until achieving muscular failure with the following percentage ranges: 30 to <40%; 40 to <50%, 50 to <60%, 60% to <70%, 70 to <80%, 80 to <90% and >90%...
March 23, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28338423/assessment-of-leg-muscles-mechanical-capacities-which-jump-loading-and-variable-type-provide-the-most-reliable-outcomes
#20
Amador García-Ramos, Belén Feriche, Alejandro Pérez-Castilla, Paulino Padial, Slobodan Jaric
This study aimed to explore the strength of the force-velocity (F-V) relationship of lower limb muscles and the reliability of its parameters (maximum force [F0], slope [a], maximum velocity [V0], and maximum power [P0]). Twenty-three men were tested in two different jump types (squat and countermovement jump: SJ and CMJ), performed under two different loading conditions (free weight and Smith machine: Free and Smith) with 0, 17, 30, 45, 60, and 75 kg loads. The maximum and averaged values of F and V were obtained for the F-V relationship modelling...
March 24, 2017: European Journal of Sport Science
keyword
keyword
76067
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"